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ECE187 Introduction to Biomedical Imaging and Sensing (4 units)
Imaging and sensing fundamentals: imaging theory, image processing, pattern recognition, digital
radiography, computed tomography, magnetic resonance imaging, ultrasound imaging, optical
microscopy, super resolution imaging, fluorescence imaging, and Raman scattering sensing.
Grading Policy:
30%
40%
40%
Problem sets
Midterm
Final
approximately 3 sets
in class, close book
in class, close book
Suggested References:
1. J. T. Bushbert, J. A. Seilbert, E. M. Leidholdt Jr, and J. M. Boone, The essential physics of
medical imaging (Lippincott Williams & Wilkins, 2011).
2. N. B. Smith and A. Webb, Introduction to medical imaging: physics, engineering and clinical
applications (Cambridge, 2011).
3. J. Mertz, Introduction to optical microscopy (Roberts and Company Publishers, 2010).
Course Outline:
- Introduction – biomedical imaging and sensing at a glance
- General image characteristics, data acquisition and image reconstruction
Spatial resolution, signal-to-noise ratio, contrast, image filtering, data acquisition, artifacts, Fourier
transform, sonograms.
- X-ray planar radiography and computed tomography
Introduction of X-ray, instrumentation for planar radiography, X-ray contrast agents, computed
Tomography (CT), image reconstruction in CT.
- Magnetic resonance imaging (MRI)
Introduction, effects of strong magnetic field on protons in the body, basis of MR signal detection, MRI
imaging and image reconstruction, MRI contrast agents.
- Ultrasound imaging
Acoustic wave fundamentals, instrumentation, ultrasound transducers, clinical diagnostic, image
characteristics, Doppler ultrasound for blood flow measurements.
- Optical imaging and sensing
Optical microscopy, fluorescence imaging, confocal microscopy, super resolution imaging, Raman
scattering and surface enhance Raman scattering for biochemical sensing.