Download Supplemental digital content 1: Search terms, criteria for study

Supplemental digital content 1: Search terms, criteria for study selection and articles
identified.
PubMed and EMBASE (1947 to present) were searched using the following terms in the format
Disease AND Setting:
Disease: Text Words [Ovary OR Ovari*] AND [tumo(u)r* OR cancer(s) OR malignanc* OR
neoplasm*] MeSH Words: Ovarian Neoplasms (PubMed only), Ovary Tumor (EMBASE only)
Setting: Text Words [Limited OR Low(er)] AND [resource OR income] AND [countr* OR
setting OR environment] OR “third world” OR [developing AND country(ies)] MeSH Words:
Developing Countries. We also included as MeSH Words the names of all lower and lowermiddle income countries as defined by the World Bank1 and all countries in Sub-Saharan Africa.
Criteria for study selection: Studies were included if they were conducted in a developing
country and mentioned each of the following: Ovarian Epithelial Cancer, Survival or Response
Rate, Specific Chemotherapeutics mentioned (dose not required). We included studies in English
or French, regardless of publication date. Studies in which surgery was the primary treatment
were excluded.
Study selection: Two reviewers (LS, LVL) screened titles and abstracts acquired from all
sources listed above for relevance and retrieved full-text of all potentially relevant titles. Two
reviewers (LS, JN) independently determined the eligibility of retrieved articles and extracted the
following information from relevant studies: Author, Year, Journal, Country, Type of Study,
Number of patients, Patient Characteristics, FIGO Stage, Chemotherapy/Dose/Cycle length,
Response Rate, Survival.
Fourteen studies were potentially relevant: 1-14
1.
Attarian H. Carboplatin combined with docetaxel as a first-line chemotherapy in
epithelial ovarian cancer. Archives of Iranian Medicine 2003;6: 176-9.
2.
Basu P, De P, Mandal S et al. Study of 'patterns of care' of ovarian cancer patients in a
specialized cancer institute in Kolkata, eastern India. Indian J Cancer 2009;46: 28-33.
3.
Charak BS, Agarwala S, Gopal R et al. Cisplatin-based chemotherapy in advanced
ovarian cancer: initial experience in an Indian set-up. Indian J Cancer 1989;26: 85-91.
4.
Dunder I, Berker B, Atabekoglu C, Bilgin T. Preliminary experience with salvage weekly
paclitaxel in women with advanced recurrent ovarian carcinoma. Eur J Gynaecol Oncol 2005;26:
79-82.
5.
Ghaemmaghami F, Karimi-Zarchi M, Modares-Gilani M et al. Clinical outcome of
Iranian patients with advanced ovarian cancer with neoadjuvant chemotherapy versus primary
debulking surgery. Asian Pac J Cancer Prev 2008;9: 719-24.
6.
Karabulut B, Sezgin C, Terek MC et al. Topotecan in platinum-resistant epithelial
ovarian cancer. Chemotherapy 2005;51: 347-51.
7.
Malik IA. An open label evaluation of topotecan in patients with relapsed or refractory
epithelial ovarian cancer - single institution experience in a developing country. Int J Gynecol
Cancer 2000;10: 443-8.
8.
Moosavi AS, Gilani MM, Tehranian A, Esfahani JK. Daily low-dose oral etoposide for
recurrent epithelial ovarian cancer after platinum-based therapy. J Obstet Gynaecol 2004;24:
292-3.
9.
Piura B, Meirovitz M. Weekly single-agent carboplatin in heavily pretreated patients with
recurrent ovarian, peritoneal and fallopian tube carcinoma. European Journal of Gynaecological
Oncology 2005;26: 386-90.
10.
Piura B, Rabinovich A. Gemcitabine in heavily pretreated patients with recurrent ovarian,
peritoneal and fallopian tube carcinoma. European Journal of Gynaecological Oncology
2004;25: 449-52.
11.
Senapad S. Chemotherapy for gynecologic malignancies at Siriraj Hospital, Bangkok.
Southeast Asian J Trop Med Public Health 1985;16: 656-9.
12.
Sonnendecker EW. Cancer of the ovary. The Johannesburg Hospital experience. S Afr
Med J 1988;73: 713-5.
13.
Sulkes A, Beller U, Peretz T et al. Taxol: initial Israeli experience with a novel anticancer
agent. Isr J Med Sci 1994;30: 70-8.
14.
Vanderpuye V, Yarney J. Ovarian cancer: an analysis of forty-four patients at the
National Radiotherapy Centre, Accra--Ghana. West Afr J Med 2007;26: 93-6.
REFERENCES
1.
World Bank Country Classification: Country and Lending Groups [database online].
Washington, DC: The World Bank Group. Updated August 2010. Available at:
http://data.worldbank.org/about/country-classifications. Accessed January 2010.