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BANK OF TEST TASK to the test control for the year Stomatological faculty CYTOLOGY During embryogenesis the epithelial band also known as vestibular plate gives rise to development of vestibule of mouth. What biological mechanism of the programmed death of cells provides growth of buccolabial sulcus from epithelial plate? A *Apoptosis B Necrosis C Meiosis D Paranecrosis E Amitosis A patient was prescribed a drug with apparent lipophilic properties. What is the main mechanism of its absorption? A *Passive diffusion B Filtration C Active transport D Pinocytosis E Binding with transport proteins Examination of a patient with hepatolenticular degeneration revealed that synthesis of ceruloplasmin protein has a defect. What organelles is this defect connected with? A *Granular endoplasmic reticulum B Agranular endoplasmic reticulum C Mitochondrions D Golgi complex E Lysosomes Microscopic analysis of human heart cells revealed some oval oganellas, their tunic being formed by two membranes: the external one is smooth, and the internal one forms crista. Biochemical analysis determined the presence of ATP-synthetase enzyme. What organellas were analysed? A *Mitochondrions B Lysosomes C Ribosomes D Endoplasmic reticulum E Centrosomes In process of the secretory cycle secretion granules come and go in the apical part of cytoplasm of pancreas cells. These granules relate to the following structure elements: A*Inclusions B Microfilaments C Lysosomes D Exocytic vacuoles E Granular endoplasmic reticulum An animal had been intensively fed with carbohydrates. Histologic examination of its liver revealed a significant number of glycogen granules. Glycogen relates to the following group of cell structures: A *Trophic granules B Secretory granules C Excretory granules D Pigment granules E Special organelles Electron microscopic study of a cell revealed roundish bubbles confined by a membrane and containing a lot of various hydrolytic enzymes. It is known that these organelles provide intracellular digestion and protective functions. These elements are: A *Lysosomes B Centrosomes C Endoplasmic reticulum D Ribosomes E Mitochondria Formation of ribosome subunits in a cell was disturbed in course of an experiment (by means of activated mutagenic factors). This will have an effect on the following metabolic process: A *Protein biosynthesis B Carbohydrate biosynthesis C ATP synthesis D Photosynthesis E Biological oxidation A 50 year old woman had her tooth extracted. The tissue regenerated. Which of the following organelle are the most active during tissue regeneration? A *Ribosomes B Centrioles C Polysomes D Smooth endoplasmic reticulum E Lysosomes In histological preparation of nervous tissue you can see, that neurons unite are connected together by means of contacts that are specialized for the one-sided transmission of nervous impulse. Specify, what type of intercellular connection is educed on preparation? A *Synapse. B Desmosome C Simple D Tight junctions E Gap junction Harmful ecological factors resulted in the sharp falling of endocytosis and exocytosis in the cells of liver and blood. What layer of cytolemma was suffered first of all? A *Cortical B Lipoprotein C Supra membrane D Integral E Glycocalyx Existence of life at all his levels is determined by the structure of lower level. What level of organization is preceded and provided the existence of life at cellular level: A *Molecular B Tissue C Organism D Population E Biocoenosis Support of life at any level is related to the phenomenon of reproduction. In what level of organization is reproduction done on the basis of matrix synthesis? A * Molecular B Subcellular C Cellular D Tissue E Levels of organism During the histological research was found a great number of granules of glycogen in the cells of liver according to the excessive feeding of animals by carbohydrates. What activity of these organelles indicates this fact? A *Trophic inclusion B Secretory inclusion C Excretory inclusion D Pigment inclusion E Non membrane organelles Two different organelles that destroy the proteins are visible on the electronic photomicrograph of the cell? What kind of organelles are they? A *Lysosome and proteasome B Endoplasmic reticulum and microfilaments C Peroxisome and ribosome D Ribosome E Golgi apparatus and microtubules During the cytochemical research a light content of hydrolytic enzymes was found in the cytoplasm of cell. What activity of organelles indicates this fact? A *Lysosomes B Endoplasmic reticulum C Mitochondrion D Polysome E Centosome During the electronic microscopy in the cytoplasm of cell, near the cell nucleus, was found a membranous organelle that consists of 5-10 flat cisterns, with the extended peripheral areas from which little blisters – (lysosomes) are disconnected. Name this organelle: A * Golgi apparatus B Ribosome C Mitochondrion D Cytoskeleton E Centrosome On the electronic photo organelle is presented which is a large polyproteasome complex that consists of tube like and two regulator parts, was located on both ends of organelle. The last performs the function of proteolysis. Name this organelle. A *Proteasome B Centriole C of Inclusions D Ribosome E Golgi apparatus During the studies of epithelial cells of oral cavity on the surface of cell’s nucleus appear the rounded little bodies that indicated that cells are taken from the oral cavity of woman. How is such a formation of chromatin called? A *Barr corpuscles B Herring corpuscles C Euchromatin D Pacinian corpuscles During the forensic research of blood sample in neutrophils on the surface of one of segments of cell’s nucleus the chromatin appears as a drumstick. How is such structural formation called? A *Barr corpuscles B Layon corpuscles C Chromatin D Euchromatin E Pacinian corpuscles In the certain cells of adults during their lifelong there is no mitosis and quantitative content of DNA remains constant. These cells are: A * Neurons B Endothelia cells C Muscle (smooth) D Epidermis E Blood forming Analysis of an electron diffraction pattern of a cell revealed mitochondrion destruction. This might result in abnormal course of the following cell process: A *Oxidation of organic substances B Nuclear division C Crossingover D Cleavage E It is known that information about sequence of amino acids in a protein molecule is encoded as a sequence of four types of nucleotides in a DNA molecule, and different amino acids are encoded by different number of triplets - from one to six. Such peculiarity of the genetic code is called: A *Degeneracy B Universality C Nonoverlapping D Triplety E Specificity A chemical factor had an effect on the cell membrane. As a result a cell has changed its shape. What layer of cell membrane was participated in it? A * Cortical B Glycocalyx C Two lipids layer D Hydrophilic E Hydrophobic Sometimes it is necessary to do research of somatic cells for determination of sex of human. What their structures can provide the information about sex of human? A *Peripheral chromatin B Euchromatin C Decondensation chromatin D Barr corpuscles E Optional chromatin In a muscular tissue there is an intensive aerobic process of accumulation of energy as macro energetic connections ATP. This process takes place due to the participation of such organelles as: A *Mitochondrion B Smooth endoplasmic reticulum C Lysosomes D Rough Endoplasmic Reticulum E Centrosome Submicroscopic not membranous organelles of general-purpose – microtubules are built from the following protein like: A *Tubulin B Desmine C Keratin D Vimentine E Actinin Centrioles in their basis contained microtubules which are oriented parallel and have such a formula as: A * (9 х 3) + 0 B (9 х 2) + 2 C (9 х 3) + 2 D (9 х 2) + 0 E (9 х 3) + 3 On preparation appears a histological structure that is limited by the membrane which has a volume cytoplasm and plenty of nucleuses. What name this structure has? A *Symplast B Syncytium C Ground substance D Cell E Vacuoles In the post-synthetic period of mitosis cycle was broken synthesis of proteins - tubulins that take part in formation of spindle of division. It can result in violation: A *Of divergence of chromosomes B Of duration of mitosis C Of spiralisation chromosomes D Of cytokinesis E Of antispiralisation chromosomes On histological preparation painted by dye ferrous hematoxylin a dumbtellshaped cell is presented, in the poles of that visible spiralisation of chromosomes. In what phase of cellular cycle is the cell? A *In telophase B In anaphase C In metaphase D In prophase E In interphase Scraping is done from the mucous membrane of cheek by means of spatula, a smear is made and painted by methylene blue. Under a microscope near the internal membrane of nucleus of epithelial cells are visible the semispherical lumps of heterochromatin. What is the structure? A *Barr corpuscles B Fordyce spots C Buccal fat pad D У-chromosome E Ribosome On an electronic photomicrograph is visible the fibroblast that products the components of intercellular substance. Define organelles that take part in this process? A * Rough Endoplasmic Reticulum and Golgi complex B Smooth endoplasmic reticulum and Golgi complex C Golgi complex and mitochondrion D Golgi complex and lysosomes E the Granular and smooth endoplasmic reticulum Ultramicroscopic examination of “dark” hepatocytes population in the cell cytoplasm detected a developed granular endoplasmic reticulum. What function has this organelle in these cells? A *Synthesis of protein of blood plasma B Synthesis of carbohydrates C Detoxification D Products of bile E Depositing ions of calcium From the cell was excluded Golgi complex by means of micromanipulator. How it will affect in later existence of cell? A *Will be broken formation of lysosomes, maturation of secretory products of cell B Will be broken by the process of mitosis C Will be broken by the formation of ribosomes and synthesis of proteins D Will develop autolysis, can lead cell to death E Will be broken by processes of power exchange EMBRYOLOGY During gastrulation the Hensen's node remained underdeveloped in the embryo. Which axial organ will slow down its development? A *Chord B Neural crests C Neural groove D Neural tube E Mantle layer of the neural tube Microspecimen analysis of child's finger skin revealed that epidermis has signs of inadequate development. What embryonal leaf was damaged in the process of development? A *Ectoderm B Mesoderm C Endoderm D Mesenchyme E Ectomezenchyme During the experimental analysis of chondrohistogenesis a sclerotome was damaged. What cells will it make impossible to differentiate? A *Chondroblasts B Smooth myocytes C Myoblasts D Fibroblasts E Epidermocytes Microspecimen of a child's finger skin reveals subnormal development of epidermis. What embryonic leaf was damaged in course of development? A *Ectoderm B Mesoderm C Endoderm D Mesenchyme E Ectomesenchyma At a certain stage of development of a human embryo one can observe formation of a cavity in its structure, small light blastomeres on the periphery and large dark blastomeres at one of the poles. The embryo at this stage of development is called: A *Blastocyst B Morula C Zygote D Gastrula E Blastodisk For an unknown reason the fertilization membrane of an embryo dissolved in the fallopian tube in the first critical period. What complication of pregnancy is possible in this case? A *Embryo implantation into the Fallopian tube B Embryonic death C Invagination of the blastocyst wall D Return of blastocyst back to the ampullary portion of the tube E Formation of two blastocysts By producing a number of hormones placenta plays a part of temporary endocrine gland. What hormone may be detected in woman's blood on the third or the forth day after begin of implantation, that is used in medicine for early pregnancy detection? A *Chorionic gonadotropin B Somatostatin C Progesterone D Vasopressin E Oxytocin Implantation process has two stages: adhesion and invasion. Morphological manifestation of blastocyte adhesion is: A *Attachment of blastocyte to the endometrium B Destruction of endometrium epithelium C Destruction of connective tissue of endometrium D Destruction of endometrium vessels E Formation of lacunes A newborn child has microcephalia. Doctors consider that this is the result of mother's taking actinomycin D during the pregnancy. What embryonal leaf was influenced by this teratogen? A *Ectoderma B All leaves C Entoderma D Mesoderma E Entoderma and mesoderma Examination of uterine cavity revealed an embryonated ovum that wasn't attached to the endometrium. The embryo is in the following stage of development: A *Blastocyst B Zygote C Morula D Gastrula E Neurula Examination of a pregnant woman who has been taking alcohol revealed diturbed anlage of ectoderma during the fetal life. What derivatives of this leaf have defects? A *Neural tube B Kidneys C Bowels epithelium D Liver E Sexual glands Microscopic examination of oval shaped cell, with the size of 150 mkm, reveals cytoplasm with yolk, but doesn’t reveal centrioles. What kind of cell is it? A *Oocyte B Leucocyte C Myocyte D Fibroblast E Macrophage In the cavity of uterus there was revealed the embryo which isn’t attached to endometrium. What stage of development is it? A *Blastocysts B Zygote C Morula D Neurula E Gastrula In the process of embryonic ectoderm differentiation a neural tubule, nervous combs, neurogenic placodes, skin ectoderm and lamina prechordalis are developed. How is the process of forming a neural tubule defined? A *Neurulation B Gastrulation C Somytogenesis D Histogenesis E Organogenesis In preparation is visible an oocyte in the moment of impregnation it by spermatozoid. What is the main result of impregnation? A *Formation zygote B Determination sex of child C Completion of meiosis an oocyte D Penetration by spermatozoon an ovolema E Cortical reaction Implantation of embryo into the mucous membrane of uterus consists of two phases - adhesion and invasion. First phase accompanied by: A * Attaching blastocyst to the surface of endometrium B Destruction of connecting tissue of endometrium C Destruction of epitheliocytus of endometrium of uterus D Activation of secretion of uterus glands E Oppression of secretion of uterus glands In a blastocyst which is, covered by tunicate impregnation, genetically inhibited the synthesis of lytic hormones in the cells of the trophoblast. What process of embryogenesis can be done or can be delayed? A * Implantation B Delamination C Immigration D Gastrulation E Epibolation In preparation of main end of embryo, with the length of 6 mm, on the front surface of neck are visible piatenlike increases that appeared due to proliferation of mesenchyme. How these formations of branchial apparatus are defined? A *Branchial arches B Branchial fissures C Branchial pockets D Branchial membranes E Pharyngeal pockets On the certain stage of ontogenesis of human is established during the certain stage of human ontogenesis. This function is performed by the provisionally organ: A *Placenta B Yolk sac C Amnion D Umbilical cord E Allantois In preparation of main end of embryo of 5-th week formation are developments of branchial arcs. What form of first pair of these formations? A *Mandibularies and Maxillaries B Mandibularies processus C Maxillaries processus D External acoustic duct E Thyroid cartilage In the first critical period in the fallopian tube without reason in an embryo was dissolution of fertilization membrane. What complication of pregnancy is possible in this case? A *Implantation of embryo in the wall of the uterus tube B Death of embryo C Invagination wall of blastocyst D Return blastocyst back into the ampulla parts of uterus tube E Formation of two blastocysts One of critical periods of embryogenesis of human is implantation of embryo into wall of uterus during 7th days. What process of gastrulation take place in the embryoplast in this period? A *Delamination B Migration C Epibolation D Invagination E Neurulation At microscopic research of internal genital woman organs that were remote during operation was found embryo built from two blastomeres. Name the place of it localization on condition of normal development. A * Fallopian tube (uterus tube) close to ampulla parts B Fallopian tube, close to uterus part C Cavity of uterus D Abdominal region E Ovary During the gastrulation embryo goes through the hystotroph to the haematotroph methods of feeding. What pharmacist organ does provide it first? A *Chorion B Trophoblast C Yolk sack D Amnion E Allantois The antigen of tissue compatibility of child inherits from a father and mother. It is known that expression of paternal antigens in embryogenesis begins before time. But the immune system of mother doesn't tear away an embryo. What organ first of all is prevent rejection an embryo of mother organism? A *Chorion B Amnion C Allantois D Yolk sack E Umbilical Cord On the micro preparation of human embryo, taken from involuntary abortion, is educed an embryonic corymb, in what recognized two layers of the cell: ento- and ectoblast. In what stage of embryonic development was an embryo? A *Gastrulation B Progenesis C Neurulation D Histogenesis E Organogenesis During forensic examination of woman, which perished in an accident, an embryo was found on the stage of early gastrula. Name the place of it localization on condition of it normal development. A *Wall of uterus B Ampulla part of tubes uterus C Fallopian part of tubes uterus D Ovary E Abdominal region Ecto- and entoderm are formed in the period of early gastrulation. In what mechanism these sheets appeared? A *Delamination B Invagination C Epibolation D Immigration E Invagination, Epibolation Spermatozoids move on woman genital tracts to side of ovule against liquid (distant stage of impregnation). What name has this directed movement? A *Rheotaxis B Thermotaxis C Chemotaxis D Capacitaion E Acrosome reaction In embryogenesis of human in a 20-th day there is dissociating of embryo's body from pharmacist organs. In what way this process is provided? A *Truncal fold B Amnion fold C Celom D Yolk sack E Somits In preparation of 10-daily embryo of human 2 bladders can be seen, that contact together (amniotic and vitelline). What is the structure that lies in the place of their contact? A *Embryonic corymb B Bottom of amnion C Roof of yolk sack D Amniotic leg E Fetal of mesoderm It is known that some microorganisms that cause infectious diseases can pass through a placenta barrier. What structures are included in its composition? A *All structural components of third villi B Chorion and amnion C All structural components of secondary villi D Allantois, yolk sack E Basal lamina of endometrium with decidual cells During histological preparation is determined a great number of mucous connective tissue (Wharton's jelly), vessel, and also bits and pieces of vitelline stem, and allantois. What is the organ? A *Umbilical cord B Esophagus C Ureter D Urinary canal E Vermicular appendix Microscopic research of embryonic material in preparation is determined a yolk sack. What is the function of this organ for human? A *Hematopoesis B Trophic C Products of amniotic fluid. D Excretory E Protective During formation of human embryo it is possible to see in his composition a cavity, light shallow blastomeres on periphery and dark large blastomeres on one of poles. How is an embryo defined on this stage of development? A *Blastocysts B Morula C Zygote D Gastrula E Embryo of disk Microscopic research of embryo membranes is determined a chorion. What basic function is provided by this organ? A *Metabolism between the organism of mother and fetus B Hematopoesis C Products of amniotic fluid D Formation of primary gametes E Formation of lymphocytes In an embryo wasn’t formed primary Hensen’s node during gastrulation. The development of what axial organ will be inhibiting? A *Chorda B Neural crest C Neural groove D Neural tube E Mantle layer of the neural tube The process of splitting of the zygote ends with the blastula formation. What type of blastula is typical for a human? A *Blastocysts B Coeloblastula C Discoblastula D Amphiblastula E Morula The gametes precursors (gonoblasts) were revealed in the embryo at 2nd-3rd weeks of embryogenesis. Where are these cells differentiated? A *In the yolk sac B In the mesenchyme C In the embryonic ectoderm D In dermatomes E In the embryonic endoderm The myotome was destroyed in the rabbit embryo during the experiment. Disorder of what structure can be caused by this manipulation? A *Skeletal muscle B Axial skeleton C Skin connective tissue D Smooth muscle E Serous membrane In the early stage of development (4 -10 week) in the main section of human embryo are found the bulges, covered by the thin layer of epidermis, basis of which is formed by a mesenchyme. What the formation is it? A The branchial arches B The branchial fissures C The branchial pockets D The pallatin processus E The frontal processus As a result of the expression of individual components of genome, cells of embryo acquired characteristic morphological, biochemical and functional features. What name this process has? A *Differentiation B Capacitation C Reception D Determination E Induction Endoscopic research in the cavity of uterus was found the human embryo, which was attached not fastened to endometrium. What stage of embryogenesis is it? A *"Free" blastocyst B Zygote C Morula D Gastrula E Neurula Due to microscopic research of internal genital woman organs, that were remoted during surgery, there was found an embryo that consists of 16 blastomeres covered by a specific membrane. How is this membrane named? A *Membrane of fertilization B Corona radiata C Corona pollucida D the Cellular membrane E Oolemma The 25-years-old woman visited a doctor – gynecologist abortion that happened on the 24th week of pregnancy. During the detailed examination doctor set pathology in development of Chorion (child's part of placenta). What rudiment did undergone changes? A *Trophoblast B Endoderm C Ectoblast D Epiblast E Mesenchyme What biological value has the process of impregnation that takes place during conferencing of male and female gametes? A *The zygoid set of chromosomes recommences, determination of genetic embryo sex comes true, cleavage is initiated B Formation of blastocysts C Formation of Blastomeres D Implantation is initiated E Formation of Morula The compression of umbilical cord of embryo is happened, but circulation of blood between an embryo and mother wasn't disturbed. Presence of what structures contributed it first of all: A *Mucous connective tissue B Remain of allantois C Layer of arteries D Layer of vein E Remain of vitelline stem At an impregnation due to insufficiency of acrosome reaction dissolution of contacts wasn’t done between the follicle cells of grainy zone of oocyte. What process was detected? A *Denudation B Capacitaion C Cortical reaction D Elimination E Modification A woman had infected by flu and it was appeared that it happened on 7-14 days of pregnancy. What consequences can appear? A *Detection of formation of ecto- and endoderm B Detection of formation of mesoderm C Detection of formation of mesenchyme D Detection of process of Epibolation E Detection of process of invagination A bounded vesicle with intestinal tube which is one of main organs is visible on micro section of human embryo. Primary gametes and primary red corpuscles (megaloblasts) are located in his wall. Define, what is the main organ? A. *Yolk sack B. Allantois C. Placenta D. Umbilical cord E. Amnion The cut of organ is presented on histological preparation. Its basis is formed by a mucous connective tissue, two arteries and vein. What organ is it? A. *Umbilical cord B. Allantois C. Yolk sack D. Amnion E. Placenta Outgrowth of ventral wall of primary bowel, which is growing in amniotic leg, is developed in the early stages of development of human embryo. What is the name of this organ? A. *Allantois B. Yolk sack C. Amnion D. Placenta E. Umbilical cord In the conventional experiment fully inhibited the development of cells of mesenchyme. The disturbance development of what muscular tissue will be observed? A *Of the smooth muscular tissue of visceral type B Of the muscular tissue of neural type C Of the muscular tissue of epidermal type D Of the cardiac muscular tissue E Of the skeletal muscular tissue Gastrulation is a period of embryogenesis, in what formed embryonic sheets, as a result of what an embryo acquires the threestratified structure. What mechanism of gastrulation is characteristic for the human embryo? A *Delamination and immigration B Invagination C Epibolation D Immigration and invagination E Delamination and Epibolation In normal condition circulation mothers blood and fetus doesn't have direct connections. Blood of fetus flows on the vessels of Chorion villi, and mothers - circulates in between villi space endometrium of uterus. What shares mother blood from fetus blood? A *Haemochorion barrier B Connective tissue partitions C Fibrinoid of Langance D the Amorphous fibrinoid of Рора E the Locking plate of basic meatus of uterus In slide is visible an oocyte in the moment of fertilization it by spermatozoid. Where does this process occur in normal condition? A *In ampulla part of fallopian tube B In an abdominal cavity C On the surface of ovary D In the uterus E In the isthmus of fallopian tube A fetus membrane organ on the early stages of embryogenesis has a monolayer flat epithelium, which is from the third month acquires a prismatic and cube form, participates in making of amniotic fluid. Name this organ: A. *Amnion B. Yolk sack C. Allantois D. Umbilical cord E. Placenta For diagnostics few micro slides are presented that are made of embryos age of two-eight weeks of embryo its development. By what sign (beginning of period) is it possible to recognize this stage of embryo development on a micro slide? A. *Formation of primary stripe B. Cleavage C. Gastrulation D. Placentation E. Neurulation For diagnostics few micro slides are presented that represent the primary development period of human that lasts the first seven days to embryogenesis. By what sign (beginning period) is it possible to recognize this stage of embryo development on a micro slide A. *Fertilization B. Cleavage C. Gastrulation D. Placentation E. Neurulation Epithelial tissue Study of a tubular organ revealed that its median membrane consists of solid hyaline rings. What epithelium lines mucous membrane of this organ? A *Multinuclear prismatic ciliated B Monostratal prismatic glandular C Monostratal prismatic with a border D Multistratal squamous nonkeratinizing E Monostratal cubical Histological examination of a tissue sample revealed that the tissue had no blood vessels, and the cells were packed tightly together making layers. Specify this tissue: A *Epithelial B Cartilaginous C Osseous D Nervous E Muscular In the experiment tight connections between the epitheliocytes were damaged. What function of the epithelium will be disordered? A. *Mechanical B. Absorption C. Vitamin D production D. Secretory E. Excretory Histological investigation of the tissue revealed absence of blood vessels in it and tight connections between the cells with formation of layers. What tissue is it? A. *Epithelial B. Cartilage C. Bone D. Nervous E. Muscle On the electron microphotograph of epithelial tissue under epitheliocytes damaging of the basal membrane were revealed. What main function of the epithelium is disordered? A. *Barrier B. Absorption C. Regeneration D. Secretory E. Exocytose In a histological specimen the gland adenomeres should be determined. They are formed by the cells with central round nucleus and basophilic cytoplasma. Determine the type of adenomeres: A *Serous B Mucous C Combined D Sebaceous E Seromucous Tunica intima of the vessel is lined with epithelium. Name it. A. *Endothelium B. Mesothelium C. Epidermis D. Transitional epithelium E. Pseudostratified epithelium In a histological specimen of the small intestine villi were determined. They covered with tissue which has only cells that rest on the basal membrane. There are no blood vessels. What tissue covers villi? A. *Epithelial tissue B. Dense irregular connective tissue C. Loose connective tissue D. Smooth muscle E. Reticular tissue In the study of the epithelium revealed that it is composed of several layers of cells. Epithelial cells of the outer layer have no nuclei. What is the kind of the epithelium? A * Keratinizing stratified squamous epithelium B Non-keratinizing stratified squamous epithelium C Transitional D Stratified columnar ciliated epithelium E Stratified cuboidal epithelium The rounded bodies that indicate that the cells were taken from the female mouth were revealed during the studies of the oral cavity epithelial cells. What is the formation of a chromatin? A *Barr bodies B Lyon bodies C Decondensed chromatin D Euchromatin E Pacinian corpuscles Blood Rejection of transplant developed in the patient after transplantation of heterogenous kidney. Call main effector cells, which take place in this immune reaction? A. *T killer B. B lymphocytes C. T suppressor D. T helper E. Plasma cells Plasma cell produces specific antibody for specific antigen. During injection of antigen quantity of plasma cell increased. At the expense of what blood cells occurred increasing of plasma cells quantity? A. *B lymphocytes B. Eosinophils C. Basophils D. T lymphocytes E. Monocytes During heterotransplantation of the organ was revealed rejection of transplant. What blood cells will ensure this process? A. *T killer B. T helper C. T suppressor D. T 0 lymphocytes E. T memory cells After investigation laboratory doctor has made an additional conclusion that blood belongs to a woman. Peculiarities of which formed elements helped him to make this suggestion? A. *Neutrophils B. Erythrocytes C. Lymphocytes D. Monocytes E. Basophils Burn wound was closed by pig skin (heterotransplantation). Call effector cells which will reject transplant. A. *T killer B. T helper C. T suppressor D. B lymphocytes E. Natural killer In the blood of a patient with infection small amount of specific antibodies were revealed. Function of which cells of connective tissue is depressed? A. *Plasma cells B. Lymphocytes C. Macrophages D. Neutrophils E. Mast cells The helminthiasis was detected at the child (10 years). What changes in the leukogram can be expected? A *Number of eosinophils will increase B Number of platelets will increase C Number of red blood cells will increase D Number of segmented neutrophils will increase E Number of basophils will increase The cells with the histamine and heparin granules in the cytoplasm were defined in the blood smear. What is the kind of the cell? A *Basophils B Neutrophils C Eosinophils D Monocytes E Erythrocytes During investigation of the patient blood smear in the neutrophils were revealed bacteria. How did they appear their? A. *Phagocytosis B. Passive transport C. Active transport D. Excretion E. Pinocytosis During tooth extraction patient has longer bleeding from the wound compared with normal. Insufficient amount of what formed elements of the blood caused increasing time of bleeding? A. *Platelets B. Erythrocytes C. Monocytes D. Lymphocytes E. Neutrophils 6 years old child has hospital treatment with diagnosis allergic rhinitis. Changes in the leukocytic formula have been found. Amount of what cells among leucocytes can be enlarged? A. *Eosinophils B. T lymphocytes C. B lymphocytes D. Basophils E. Neutrophils 5 years old child has helminthes invasion, which caused organism sensibilization. What changes in the leukocytic formula can be expected? A *Increasing of the eosinophils number B Increasing of the neutrophils number C Reducing the eosinophils number D Increasing of the monocytes number E Increasing of the lymphocytes number Inflammatory process in the tissues and organs is accompanied with hyperemia and edema. What connective tissue leucocytes are causing these changes? A *Basophils B Eosinophils C Neutrophils D Lymphocytes E Monocytes During postembryonal haemopoiesis in the red bone marrow the cells of one of the cellular differons demonstrate a gradual decrease in cytoplasm basophilia as well as an increase in oxyphilia, the nucleus is being forced out. Such morphological changes are typical for the following haemopoiesis type: A *Erythropoiesis B Lymphopoiesis C Neutrophil cytopoiesis D Eosinophil cytopoiesis E Basophil cytopoiesis Filopodia of megakaryocytes enter lumen of the vessels through sinusoidal capillaries fenestrae of red bone marrow and become fragmented in smaller parts. What formed elements of the blood will be formed in this way? A. *Platelets B. Erythrocytes C. Lymphocytes D. Reticulocytes E. Monocytes Blood analysis of a 16-year-old girl suffering from the autoimmune inflammation of thyroid gland revealed multiple plasmatic cells. Such increase in plasmocyte number is caused by proliferation and differentiation of the following blood cells: A *B-lymphocytes B T-helpers C Tissue basophils D T-killers E T-supressors In the experiment ribosomes of the poly chromatophil erythroblasts were destroyed in the human red bone marrow. Synthesis of what specific protein will be disordered? A. *Globin B. Fibrinogen C. Collagen D. Elastin E. Laminine The rounded cells with the segmented nuclei are predominating from the leukocytes in the smear of peripheral blood. The granules of their cytoplasm stained both acidic and basic dyes. What are these cells? A *Segmented neutrophils B Basophils C Eosinophils D Young neutrophils E Monocytes The large cells with low-basophilic cytoplasm and bean-shaped nucleus were founded in a blood smear. The cell is the largest from visible in the visual field. What are the cells? A *Monocytes B Macrophages C Plasmocytes D Middle lymphocytes E Small lymphocytes The cells of granulocytic series were revealed at the biopsy material of red bone marrow. Specify what changes occur in the nucleus during the differentiation of these cells? A *Segmentation B Polyploidisation C Pyknosis D Enucleation E Increasing the size The cells, which accounts for 0,5% of the total leukocytes number with the S-shaped curved nucleus and metachromatic colored granules in the cytoplasm, were founded in the patient's blood smear. What are these cells? A *Basophils B Neutrophils C Eosinophils D Monocytes E Lymphocytes In the red bone marrow specimen conglomerates of giant cells in tight connections with sinusoidal capillaries are revealed. Call formed elements of the blood which will be formed from these cells. A. *Platelets B. Erythrocytes C. Leucocytes D. Monocytes E. Lymphocytes Connective tissue A specimen of connective tissue of derma was stained with Sudan III and hematoxylin. There are clusters of big polygonal cells that turned orange. Their nuclei are flattened and located on periphery. What tissue is it? A *White adipose B Brown adipose C Reticular connective D Hyaline cartilaginous E Lamellar osseous When a wound heals, a scar takes its place. What substance is the main component of its connective tissue? A *Collagen B Elastin C Keratan sulfate D Chondroitin sulfate E Hyaluronic acid A chemical burn of esophagus caused it's local constriction as a result of scar formation. What cells of loose connective tissue take part in scar formation? A *Mature specialized fibroblasts B Immature nonspecialized fibroblasts C Fibrocytes D Miofibroblasts E Fibroclasts In loose connective tissue of the salivary glands revealed oval shape middle size cells which synthesized antibodies. Spherical eccentrically positioned nucleus with chromatin clumps of which resemble cartwheel or clock face. Call these cells. A. *Plasma cells B. Adipose cells C. Neutrophils D. Fibroblasts E. Macrophages Chronicle inflammation of the gingiva is finished with excessive excrescence of connective tissue fibers. What cells took active place in this process? A. *Fibroblasts B. Osteoblasts C. Fibrocytes D. Macrophages E. Osteoclasts A foreign body entered into the skin and leads to inflammation development. What connective tissue cells take place against the foreign body in the skin reaction? A *Neutrophils, macrophages, fibroblasts B Macrophages C Melanocytes D Adipocytes E Adventitial cells During investigation of connective tissue slides neutrophils are revealed. What function do these cells have when they leave blood and enter tissue? A. *Microorganisms phagocytosis B. Trophic C. Support D. Regulation of smooth muscle cells contraction E. Expand blood vessels Decreased blood supply of the organs causes hypoxia that activates fibroblasts function. Volume of what elements does increase in this case? A *Intercellular substance B Vessels of microvascular bed C Nerve elements D Parenchymatous elements of the organ E Lymphatic vessels The damaged Achilles tendon function was renewed after the treating. What is the mechanism of tendon regeneration? A *Synthesis of the collagen fibers B Synthesis of the hyaline cartilage C Formation of the adipose tissue D Synthesis of the fibrous cartilage E Replacements of the place of injury by the muscle tissue A patient underwent Caesarean section. During the operation a long incision was made in the uterus wall and the fetus was extracted from uterus. Healing of the sutured myometrium will proceed in the following way: A *Formation of a fibrous cicatrix B Formation of smooth muscular tissue C Formation of cross-striated muscle fibers D Proliferation of myosatellitocytes E Hypertrophy of smooth myocytes The lower limb was injured during the athlete training. Traumatologist made the diagnosis: the tendon rupture. What type of connective tissue the tendon belongs to? A *Dense regular fibrous tissue B Dense irregular fibrous tissue C Loose connective tissue D Reticular tissue E Cartilage tissue In loose connective tissue histological specimen revealed relatively big cells with basophilic metachromatic granularity. These granules include histamine and heparin. Call these cells. A. *Mast cells B. Fibroblasts C. Macrophages D. Plasma cells E. Adipose cells Connective tissue consists of parallel collagen fibers separated by fibroblasts. What is the name of this type of connective tissue? A. *Dense regular connective tissue B. Loose connective tissue C. Reticular connective tissue D. Dense irregular connective tissue E. Mucous connective tissue Cartilage As a result of a chest trauma the costal cartilage was damaged. The cartilage regenerates due to the following layer of perichondrium: A *Chondrogenic B Fibrous C Elastic D Collagen E Sharpey's fibers Regeneration of articular cartilage of the mandible after damage is a great problem for traumotologists and dentists. What is the reason of limited hyaline cartilage regeneration of the bone articular surface? A. *Absence of the perichondrium B. Absence of isogenic groups C. Presence of the vessels D. Huge mechanic loading E. Large content of nonorganic compounds In the histological connective tissue specimen that stained with hematoxylin eosin revealed isogenic groups of cells surrounded by ground substance. Fibrous structures are not visible. What tissue is represented in the slide? A *Hyaline cartilage B Elastic cartilage C Dense regular connective tissue D Fibrous cartilage E Bone tissue In the result of chondrodisplasia (anomaly of cartilage development) fiber cartilage was damaged. Where pathological changes can be seen? A. *In the intervertebral discs B. In the auricle C. In the trachea D. In the pharynx E. In the bronchi The two slides were proposed to the student. At the 1 st one there is the elastic cartilage (stained by the orcein), at the 2 nd one – the hyaline cartilage (stained by the hematoxylin-eosin). According to what features can we tell one from the other? A *Presence of the elastic fibers B Presence of the cells isogenic groups C Presence of young cartilage zone D Presence of the perichondrium E Presence of amorphous substance The articular cartilage, as it is known, doesn’t have the perichondrium. What kind of growth is possible at this cartilage during the regeneration process? A *Interstitial B Appositional C By application D Appositional and interstitial E It is not growing During the experimental analysis of chondrohistogenesis a sclerotome was damaged. What cells will it make impossible to differentiate? A *Chondroblasts B Smooth myocytes C Myoblasts D Fibroblasts E Epidermocytes The isogenic cell groups were revealed at the histological slide of the cartilage. What cells are the primary in the formation of these groups? A *Chondrocytes I type. B Chondroblasts C Prechondroblasts D Chondrocytes II type E Chondrocytes III type Bone tissue The symptoms of regeneration process (callus) on the place of fracture were revealed in the histologic specimen of tubular bone. What tissue forms this structure? A *Fibrous bone tissue B Loose connective tissue C Reticular tissue D Epithelial tissue E Lamellar bone tissue Examination of a histological specimen of tubular bone revealed signs of regeneration process (callus). What tissue is this structured formed of? A *Rough fibrous osseous B Loose connective C Reticular D Epithelial E Lamellar osseous A histological specimen presents the tissue that contains cells having no processes and a few tens of nuclei each. One of cell surfaces has a corrugated zone that provides secretion of hydrolytic elements. What tissue is it? A *Osseous tissue B Cartilaginous tissue C Epithelial tissue D Nerve tissue E Muscular tissue Calcification of the intercellular substance of bone tissue is accompanied by the deposition of hydroxyapatite crystals along the collagen fibers. This process requires the presence of alkaline phosphatase in the intercellular substance. What cell produces this enzyme? A *Osteoblast B Osteocyte C Osteoclast D Chondroblast E Chondrocyte Calcification of the intercellular substance of bone tissue is accompanied by the deposition of hydroxyapatite crystals along the collagen fibers. This process requires the presence of alkaline phosphatase in the intercellular substance. What cell produces this enzyme? A *Osteoblasts B Osteocytes C Osteoclasts D Chondroblasts E Chondrocytes There are histogenetic cells row among bone tissue cells. What cells don’t constitute differon? A. *Osteoclasts B. Stem cells C. Osteocytes D. Osteoblasts E. Osseus stem cells There are two ways of bone development during histogenesis. What period doesn’t typical for direct osteogenesis? A. *Formation of epiphyseal center of ossification B. Formation in the mesenchyme precursor of the bone C. Osteoid period D. Formation of spongy bone tissue E. Replacement of spongy bone tissue by compact bone tissue In course of indirect histogenesis of tubular bone tissue a plate is formed between epiphyseal and diaphyseal ossification a center that provides further lengthwise growth of bones. What structure is it? A *Metaphyseal plate B Osseous cuff C Osseous plate D Osteon E Layer of interior general plates In the bone tissue multinucleated large cells with numerous lysosomes and ruffled border were revealed. Call these cells. A. *Osteoclasts B. Mesenchymal cells C. Stem cells D. Osteoblasts E. Osteocytes The excessive loss of bone tissue mass (it reflects the development of osteoporosis) is observed at the elderly people. Activation of whst bone cells can cause the development of this disease? A *Osteoclast B Osteoblasts C Macrophages D Tissue basophils E Osteocytes A histological specimen presents the tissue that contains cells having no processes and a few tens of nuclei each. One of cell surfaces has a corrugated zone that provides secretion of hydrolytic elements. What tissue is it? A *Osseous tissue B Cartilaginous tissue C Epithelial tissue D Nerve tissue E Muscular tissue Muscle tissue The regeneration process of damaged skeletal muscles іs very slow. What elements of musculoskeletal fiber take part in the process of regeneration? A *Myosatellitocytes B Myoblasts C Smooth myocytes D Myofibroblasts E Myoepithelial cells Striated skeletal muscle tissue has all characteristics which were listed further except: A. *Cells structure B. Contractive ability C. Presence of satellite cells D. Presence of motor plaque E. Presence of connective tissue layer Long time mice were swimming in the pool. During morphological investigation of their skeletal muscles were revealed increasing quantity of the mitochondria with cristae and light matrix. What cell function will be found in the stressful condition? A. *Energetic B. Secretory C. Synthetic D. Protective E. Transport During histological investigation of the cheek biopsy was found that it formed by skeletal muscle tissue. Call structural and functional unit of this tissue. A. *Muscle fiber B. Cardiac muscle cell C. Smooth muscle cell D. Myosatellite cells E. Myofibril In the histological specimen are revealed sheaths of the loose connective tissue that immediately surrounds individual muscle fibers and intertwined with muscle fibers sarcolemma. What histological structure has been revealed? A. *Endomysium B. Capillaries C. Nervous ending D. Actin fiber E. Myosin fiber Base of the cheek constitutes by cheek muscle which is derivative of second visceral arch. What type of muscle tissue is it? A. *Somatic B. Coelomic C. Visceral D. Neural E. Epidermal In one of the layers of the hollow organ anastomosing fibers with nucleus are revealed. Fibers consist of cells which in the connection regions forms intercalated disks. Which tissue constitutes this layer? A. *Cardiac muscle tissue B. Skeletal muscle tissue C. Smooth muscle tissue D. Dense regular connective tissue E. Dense irregular connective tissue The destruction of the thick myofilaments is observed after mechanical injury of striated muscle fibers. Where is the localization of the pathological changes? A *In the disk A B In the disk I C In the disk A half D In the A and I disks E In the disk I half Destruction of thin microfilaments is observed during the research of a striated muscle fiber after the action of hydrolytic ferments. Which structures have been damaged? A. *Actin myofilaments B. Myosin myofilaments C. Tonofibrils D. Tropocollagen complex E. Sarcoplasmic reticulum Myotom was destroyed in the rabbit embryo during experiment. Which structure development disorder has been caused by this manipulation? A. *Skeletal muscle B. Skeleton C. Skin connective tissue D. Smooth muscle E. Serous layers Fibers were presented in the histological specimen of the stomach pyloric region. They include spindle shape cells with rod like nucleus located in the center. What tissue do these cells form? A. *Smooth muscle B. Loose connective tissue C. Skeletal muscle D. Epithelial E. Reticular It is known, that calcium ions along with other factors provide muscle tissue contraction. With what structures does calcium interact during contraction? A. *Troponin protein of thin fibrils B. Myosin protein of thick fibrils C. Actin protein of thin fibrils D. Actomyosin sarcolemma complex E. Calsequestrin A microspecimen of the submandibular salivary gland shows some basket-shaped cells concentrated around the acines and excretory ducts. These cells surround bases of the serous cells and are called myoepitheliocytes. These cells relate to the following tissue: A *Muscular tissue B Epithelial tissue C Neural tissue D Special connective tissue E Loose fibrous connective tissue The regeneration process of damaged skeletal muscles іs very slow. What elements of musculoskeletal fiber take part in the process of regeneration? A *Myosatellitocytes B Myoblasts C Smooth myocytes D Myofibroblasts E Myoepithelial cells Nervous tissue A sensory nerve ganglion consists of roundish neurocytes with one process that divides into axon and dendrite at a certain distance from perikaryon. What are such cells called? A *Pseudounipolar B Unipolar C Bipolar D Multipolar E Apolar Damaged nervous fibers capable regenerate their integrity. What neuroglia cells take active place in it? A. *Olygodendrocytes B. Microglia C. Ependymal cells D. Fibrous astrocytes E. Protoplasmic astrocytes In the histological specimen of the cerebellum transverse section in its gray matter observed large amount of multipolar neurons. Due to which morphological peculiarity these cells can be classified as multipolar? A. *Amount of processes B. Length]of processes C. Shape of terminal dilation of axon D. Perikaryon shape E. Cells shape Choose one incorrect answer. Myelinated fibers have all character signs except: A. *Several axons B. One axon C. Node of Ranvier D. Neurofilaments E. Neurolemmacytes During a conditional experiment the action of toxic substance enhances the mechanism of nerve impulse transfer. What structure provides this function? A. *Synapse B. Neurolemma C. Neurofibril D. Mitochondrion E. Nissl’s body Central nervous system A ventral root of spinal cord was damaged as a result of a trauma. The following processes of the following neurons were damaged: A *Axons of motor neurons B Dendrites of motor neurons C Axons of sensory neurons D Dendrites of sensory neurons E Dendrites of internuncial neurons One of sections of central nervous system has layerwise arrangement of neurocytes. Among them there are cells of the following forms: stellate, fusiform, horizontal, pyramidal. What section of central nervous system is this structure typical for? A *Cortex of cerebrum B Spinal cord C Cerebellum D Medulla oblongata E Hypothalamus As result of a trauma, a patient has damaged frontal spinal roots. What structures are likely to be affected? A *Axons of the motoneurons and axons of the lateral horn neurons B Central processes of the sensory neurons of the spinal ganglions C Peripheral processes of the sensory neurons of the spinal ganglions D Axons of the lateral horn neurons E Dendrites of the spinal ganglion neurons A patient had a trauma that led to the injury of front spinal roots. Denote the damaged structures: A *Axons of motoneurons and lateral horn neurons B Central processes of spinal ganglion neurons C Peripheral processes of spinal ganglion neurons D Axons of lateral horn neurons E Axons of motoneurons In a specimen that was coloured by method of silver impregnation some piriform cells with 2-3 evident dendrites were found. What structure is being analysed? A *Cerebellar cortex B Spiral organ of middle ear C Retina D Cerebral cortex E Spinal ganglion In the newborn child tumor of the spinal cord gray matter was found. What embryonal germ is connected with this? A. *Mantle zone B. Ependymal zone C. Nervous cord D. Ganglionar plate E. Mesoderm As result of a trauma, a patient has damaged posterior roots of the spinal cord. What structures have been affected? A. *Sensory neurons B. Motor neurons C. Interneurons D. Dendrites of neurons of spinal ganglions E. Central processes of sensitive neurons of spinal ganglions In the microspecimen of the cerebral cortex large pyramidal cells are reveled. These cells are most significant sign of the cerebral cortex. Discover of these cells is associated with next name: A. *Betz B. Goldgi C. Lenoshek D. Nissl E. Kakhal In the histological specimen was represented precentral gyrus of the cerebral cortex. Indicate which layers development best in this layer? A. *Pyramidal, ganglionar and polymorphic cells layer (external and internal pyramidal and polymorphic cells layer) B. Molecular C. External and internal granular D. Molecular and polymorphic cells layer E. Molecular, pyramidal and ganglionar (external and internal pyramidal, molecular) Peripheral nervous system During surgical operation nerve was cut. After some period of time it regenerated. Call cell which provide its regeneration. A. *Neurolemmocytes B. Astrocytes C. Ependymal cells D. Microglia cells E. Mantle glyocytes Microscopic analysis of a specimen revealed an organ of nervous system that consists of pseudounipolar neurons covered with glial and connective tissue membranes. Determine this organ: A *Spinal ganglion B Vegetative ganglion C Spinal cord D Cerebellum E Cortex of cerebrum Sensory organs. Eye As result of punctate retinal hemorrhage a patient lost ability to see objects in the centre of visual field. In what part of retina did the hemorrhage take place? A *Yellow spot B Ciliary part of retina C Iris D Blind spot E Vascular membrane The deficit of vitamin A causes the disorder of twilight vision. What cells is the photoreceptor function typical for? A *Rod neurosensory cells B Horizontal neurocytes C Conic neurosensory cells D Bipolar neurons E Ganglionic nerve cells A histological specimen of an eyeball shows a structure in form of a convexoconvex formation connected with the ciliary body by the fibers of ciliary zonule and covered with a transparent capsule. Specify this structure: A *Crystalline lens B Vitreous body C Ciliary body D Cornea E Sclera An infectious disease caused contractive activity of muscles that contract and dilate eye pupil (paralytic state). What functional eye system was damaged? A *Accomodative B Dioptric C Ancillary D Photosensory E Lacrimal apparatus The ciliary body of a patient is damaged. Function of what eye apparatus suffers> A. *Accommodation B. Light- conductive C. Photosensory D. Protective E. Trophic A lot of people with age have clouding of the lens (phacoscotasmus or cataract) that leading to the partial or total blindness. What optical and chemical properties of the lens fibers protein will be disordered? A. *Crystallin B. Viterin C. Dinein D. Rhodopsin E. Iodopsin In a histological specimen a structure of eyeball wall is detected; blood vessels are absent in this structure. What structure is characterized by this morphologic sign? A. *Cornea B. Ciliary body C. Choroid D. Iris E. Retina In the microspecimen of the posterior eye wall was revealed undeveloped retinal pigment layer. What layer of the eye ball was injured during development process? A. *External B. Medial C. Internal D. Ganglion cells E. Mesenchyme During investigation of the ocular fundus ophthalmologist drew attention at the fovea centralis of the retina. What fovea is this? A. *Area of greatest visual acuity B. Blind spot C. Place of optic nerve exit D. Place where retina’s veins exit eye E. Place without photoreceptors cells Patient has clouding of the lens or cataract. What structure of the lens will be primary disordered in this situation? A. *Lens fibers B. Lens epithelium C. Lens core D. Lens capsule E. Ciliary fibers In a histological specimen of an eyeball a biconvex structure is connected with the ciliary body by means of the ciliary zonulae fibers and is covered with a transparent capsule from above. Name this structure: A *Crystalline lens B Vitreous body C Ciliary body D Cornea E Sclera Teenager consulted a doctor with disorder of visual acuity. Doctor explained that this problem connected with accommodation spasm. Which of mentioned components of the eye ball constitute eye accommodation apparatus? A. *Ciliary muscle B. Retina C. Vitreous humor D. Sclera E. Cornea Condition of the macula lutea was studied during ophthalmological investigation of the ocular fundus. What retina cells elements are most found in the macula lutea? A. *Cones B. Horizontal neurons C. Pigment cells D. Rods E. Ganglion cells In the electron microphotograph of the sense organ revealed cells peripheral part of which constitutes from two segments. The outer segment has membrane half discs and the inner one has ellipsoid. In what organ does this structure locate? A. *In the organ of vision B. In the organ of taste C. In the organ of smell D. In the vestibular organ E. In the auditory organ The increased intraocular tension is observed in the patient with glaucoma. Secretion of aqueous humor by the ciliary body is normal. Injury of what structure of the eyeball wall caused the disorder of flow-out from the anterior chamber? A *Venous sinus B Ciliary body C Choroid D Ciliary muscle E Back epithelium of cornea In the electron microphotograph revealed cell of neural origin. Terminal part of the cell dendrite has cylindrical shape and consists from 1000 enclosed membrane discs. What cell is this? A. *Cone cell B. Ventral horn of the spinal cord C. Sensory ganglia neuron D. Cerebral cortex neuron E. Rod cell Sensory organs. Ear As result of head trauma, a 32 year old man has damaged ampullas of semicircular ducts. be disturbed? A *Angular acceleration B Vibration C Gravitation D Linear acceleration E Vibration and gravitation What stimuli perception will A histological specimen presents a receptor zone of a sensoepithelial sense organ. Cells of this zone are placed upon the basal membrane and include the following types: external and internal receptor cells, external and internal phalangeal cell, stem cells, external limiting cells and external supporting cell. The described receptor zone belongs to the following sense organ: A *Acoustic organ B Visual organ C Gustatory organ D Equilibrium organ E Olfactory organ After having a virus disease patient has lost ability to hear. What cells of the Corti organ (spiral organ) had been damaged? A. *Receptor hair cells B. Phalangeal cells C. Outer supporting cells D. Inner supporting cells E. Pillar cells During an experiment the median part of an animal's cochlea was damaged. This resulted in impaired perception of acoustic vibrations of the following frequency: A *Medium B Low C High D High and medium E Low and medium Skin. Histological study of a microslide of human skin found only dense irregular connective tissue. Which layer of this organ was analysed? A *Reticular dermis B Papillary dermis C Subcutaneous adipose tissue D Epidermis E Basal layer of epidermis An embryon has signs of disturbed process of dorsal mesoderm segmentation and somite generation. What part of skin is most likely to have developmental abnormalities? A *Derma B Hair C Sebaceous glands D Epidermis E Sudoriferous glands What cells in the skin epidermis together with afferent fibers terminals form tactile receptors? A. *Merkel cells B. Melanocytes C. Epidermal cells of stratum basale D. Stratum spinosum cells E. Langerhans cell Human skin is very strong for the rupture. It is known that skin consists of epithelial tissue and two types of the connective tissue. Which from mentioned below tissues provide tensile strength of the skin? A. *Dense irregular connective tissue B. Stratified squamous epithelium C. Loose connective tissue D. Simple epithelium E. Transitional epithelium After the skin burn stratum basale cells were suffered. What function of the epidermis will be weakening or depressed first of all? A. *Regenerative B. Protective C. Absorptive D. Barrier E. Dielectric After ultraviolet radiation over time skin darkens. Synthesis of what substance will be activated in the melanocytes after ultraviolet radiation. A. *Melanin B. Lipids C. Eleidin D. Keratin E. Kertogyalin Under the radiation influence epidermal cells of the stratum basale were damaged. What function of the epidermis will be weakening or depressed first of all? A. *Regenerative B. Protective C. Absorptive D. Barrier E. Dielectric The reticular layer of the skin is damaged after trauma. This layer will recover with the help of a cell population. Name this cell population. A. *Fibroblast B. Macrophages C. Lymphoblastic D. Mast cells E. Plasma cells Cells with processes and dark brown granules in the cytoplasm were revealed in the skin epidermis of the biopsy material. What cell are these? A. *Melanocytes B. Intraepidermal macrophages C. Keratinocytes D. Merkel cells E. Lymphocytes With age wrinkles and plications are appeared in the human skin. Changes in which skin structures mainly caused this condition. A. *In the elastic fibers B. In the collagen fibers C. In the epidermis D. In the ground substance E. In the subcutaneous adipose tissue Histological study of a microspecimen of human skin found only dense irregular connective tissue. Which layer of this organ was analyzed? A *Reticular dermis B Papillary dermis C Subcutaneous adipose tissue D Epidermis E Basal layer of epidermis There is histological specimen of the skin epidermis bioptic sample taken from the healthy adult. Cells division can be seen in the stratum basale. What process provide these cells. A. *Physiologic regeneration B. Differentiation C. Adaptation D. Reparation E. Apoptosis On the body human surface distinguishes areas of thick and thin skin. What skin layer has different structure in these areas? A. *Epidermis B. Papillary layer C. Reticular layer D. Derma E. Hypodermis There are cells in the epidermis which have protective function and have mononuclear genesis. What cells are these? A. *Langerhans cells B. Melanocytes C. Keratinocytes of stratum basale D. Keratinocytes of stratum spinosum E. Keratinocytes of stratum granulosum Cardiovascular system. Arteries. Microcirculatory vessels. A histological specimen shows a blood vessel. Its inner coat is composed by endothelium, subendothelium and internal elastic membrane. The middle coat is enriched with smooth myocytes. Such morphological characteristics are typical for the following vessel: A *Muscular-type artery B Elastic-type artery C Capillary D Non-muscular vein E Muscular-type vein On the electron micrograph of capillary are revealed fenestrae between endothelial cells and partial or total absence of basal lamina underlying the endothelium. What type of capillary is it? A. *Sinusoidal B. Somatic C. Visceral D. Atypical E. Shunt Arterioles play an important role in the blood supply of the organs functional units. Which of these structures perform this function? A *Myocytes B External elastic membrane C Internal elastic membrane D Special connective tissue cells E Endothelial From 40 to 60 fenestrated elastic membranes were founded at the histological preparations stained by the orcein. Name this vessel. A *Artery of elastic type B Artery of muscular type C Artery of mixed type D Vein of muscular type E Vein of unmuscular type The contraction of the smooth muscle cells of arterioles occurs after the adrenalin releasing from the adrenal medulla into the blood. What are the features of these vessels structure? A * Availability of perforations in the endothelium basement membrane and the internal elastic membrane B Single position of the smooth muscle cells C Presence of the effector endings on the pericytes D Presence of the contacts between the pericytes E Availability of precapillary sphincters On a electron micrograph of a tunica intima fragment revealed cells which rests on the basal membrane and connected with each other by means of desmosomes and zonulae occludentes. Name these cells. A. *Endothelium B. Mesothelium C. Epidermis D. Epithelioreticular cells E. Macrophages In the slide of the microvascular bed vessel tunica media consists of 1-2 layers of smooth muscle cells which have spiral orientation. Tunica adventitia is a thin, sheath of loose connective tissue. What vessel is it? A. *Arteriole B. Venule C. Capillary D. Postcapillary E. Arterio-venous shunt Obliterating atherosclerosis causes changes in the vessels of the lower extremities. A histological specimen of such a vessel evidently presents both internal and external elastic membranes; middle membrane contains a lot of smooth muscle cells. What vessel is affected in case of this disease? A B C D E *Artery of muscular type Artery of elastic type Artery of mixed type Vein with strongly developed muscles Lymph node A histological specimen presents an artery. One of the membranes of its wall has flat cells lying on the basal membrane. What type of cells is it? A *Endotheliocytes B Mesotheliocytes C Smooth muscle cells D Fibroblasts E Macrophages Wall of the vessels often have huge morphological difference in the structure of the tunica media. What is the reason of appearance such specific peculiarities in the structure of this tunica in different vessels? A. *Hemodynamic condition B. Influence of endocrine system organs C. Regulation from central nervous system D. Inductive influence of vegetative ganglion neurons E. Large content of catecholamines in the blood Large arteries during systole stretch out and return in previous condition during diastole providing stability of bloodstream. What elements of vessel wall will explain this? A. *Elastic fibers B. Muscle fibers C. Reticular fibers D. Collagen fibers E. Large amount of fibroblasts In the vessel slide one found prominent internal and external elastic membranes and a lot of smooth muscle cells in the tunica media. What type of vessel is it? A. *Muscular artery B. Small artery (mixed) C. Large vein (muscular) D. Elastic artery E. Extraorganic lymphatic system Intralobular capillaries of a liver specimen have wide irregular lumen. Basal membrane is absent in the major part of the capillary. What type of capillaries is it? A *Sinusoid B Visceral C Somatic D Precapillaries E Postcapillaries Tunica intima of a vessel is lined with epithelium from within. What epithelium is this? A. *Endothelium B. Mesothelium C. Epidermis D. Transitional epithelium E. Pseudostratified epithelium Obliterating atherosclerosis causes changes in the vessels of the lower extermities. A histological specimen of such a vessel evidently presents both internal and external elastic membranes, middle membrane contains a lot of myocytes. What vessel is affected in case of this disease? A *Artery of muscular type B Artery of elastic type C Artery of mixed type D Vein with strongly developed muscles E Lymph node A histological specimen shows a blood vessel. Its inner coat is composed by endothelium, subendothelium and internal elastic membrane. The middle coat is enriched with smooth myocytes. Such morphological characteristics are typical for the following vessel: A *Muscular-type artery B Elastic-type artery C Capillary D Non-muscular vein E Muscular-type vein During investigation of skin bioptat in the derma revealed vessels which have thick layer of smooth muscle cells in the tunica media. What is the name of these vessels? A. *Muscular artery B. Capillaries C. Arterioles D. Venules E. Arterio-venous shunts In a histological specimen of tubular organ dyed with orcein have been detected about 50 thick membranes which have wiggly appearance and formed tunica media of this organ. Name this organ. A. *Aorta B. Muscular artery C. Esophagus D. Trachea E. Heart wall In a histological specimen one can see an artery. There are flat cells on the basal membrane in one of the tunics of its wall. Name these cells. A. *Endothelium B. Mesothelium C. Smooth muscle cells D. Fibroblasts E. Macrophages In the microspecimen of red bone marrow there were revealed multiple capillaries through the walls of which mature blood cells penetrated. What type of capillaries is it? A *Sinusoidal B Fenestrated C Somatic D Visceral E Lymphatic Cardiovascular system. Veins. Lymphatic vessels. Morphological examination revealed in histological specimen of biopsy material an irregular-shaped vessel. Its middle membrane is formed by bundles of smooth myocytes and layers of connective tissue. What type of vessel is it? A *Vein of muscular type B Artery uf muscular type C Lymphatic vessel D Venule E Arteriole A specimen of the pia mater shows a vessel with no middle membrane in its wall, its outer membrane adheres to the surrounding tissues, the inner membrane is made up of the basal membrane and endothelium. Specify this vessel: A *Fibrous vein B Muscular vein with weakly developed muscular elements C Muscular artery D Arteriola E Mixed artery Histological specimen presents a vessel the wall of which consists of endothelium, basal membrane and loose connective tissue. What type of vessel is it? A *Vein of non-muscular type B Artery C Vein of muscular type D Blood capillary E Lymphatic capillary A histological specimen of spleen shows a vessel with a wall consisting of endothelium and subendothelial layer, median membrane is absent, exterior membrane inosculates with the layers of spleen connective tissue. What vessel is it? A *Vein of non-muscular type B Vein of muscular type C Artery of muscular type D Arteriole E Capillary A specimen of pia mater includes a vessel whose wall doesn't have the tunica media, the tunica externa is adherent to the surrounding tissues, the intima is composed of a basement membrane and endothelium. What vessel is it? A *Nonmuscular vein B Muscular vein with underdeveloped muscular elements C Muscular artery D Arteriole E Artery of mixed type During morphological investigation in a histological specimen one can see irregularly shaped vessel tunica media of which formed by bundles of smooth muscle cells and layer of connective tissue. What type of vessel is it? A *Large vein (muscular type) B Muscular artery C Lymphatic vessel D Venule E Arteriole A specimen of the pia mater shows a vessel with no middle membrane in its wall, its outer membrane adheres to the surrounding tissues, the inner membrane is made up of the basal membrane and endothelium. Specify this vessel: A *Fibrous vein B Muscular vein with weakly developed muscular elements C Muscular artery D Arteriole E Mixed artery In histological slide are present blind ended vessels which have shape of oblate tubes. They don’t have basal membrane and pericytes. The outer surface of the endothelium is attached to the surrounding connective tissue by anchoring fibers. What type of vessel is it? A. *Lymph capillary B. Blood capillary C. Arterioles D. Venules E. Arterio-venous shunts A histological specimen shows a blood vessel. Its inner coat is composed by endothelium and subendothelial layer. The middle coat consists of smooth muscle cells bundles. Tunica adventitia well developed and consists of loose connective tissue and some smooth muscle cells. Such morphological characteristics are typical for which vessel? A *Muscular vein (large vein) B Muscular artery C Non-muscular vein D Mixed artery (small artery) E Elastic artery Cardiovascular system. Heart. During myocardium contraction in sarcoplasma of cardiac muscle cells concentration of calcium are increased. Which structure participate in calcium storage A. *L systems B. Lysosomes C. Ribosomes D. T-systems E. Nucleolus Patient A. 40 years old had myocardial infarction of left ventricle. What morphological components of the heart wall will replace this damage? A. *Proliferation of connective tissue cells B. Intracellular regeneration of contractive cardiac muscle cells C. Proliferation of contractive cardiac muscle cells D. Proliferation of conducting cells E. Proliferation of contractive cardiac muscle cells and conducting cells As a result of thrombosis of left coronary artery the group of contractive cardiac muscle cells have been destroyed. At the expense of which cells reparation in the area of damage will occur? A. *Fibroblasts B. Cardiac muscle cells C. Myosymplast D. Myosatelitocytes E. Smooth muscle cells In a slide revealed organ of cardio-vascular system. One of it coats is build by fibers which formed anastomosis between each other. They formed by cells which connected with the help of intercalated disks. Name this organ of cardio-vascular system. A. *Heart B. Large vein (muscle type) C. Muscle artery D. Elastic artery E. Arteriole In a histological specimen is represented heart wall. In one of its layers are found contractive, conducting and secretory muscle cells, endomisium and blood vessels. Which layer of the heart is it? A. *Myocardium of the atrium B. Endocardium of the ventricles C. Epicardium D. Adventitia E. Pericardium Patient A. 40 years old had myocardial infarction of left ventricle. What morphological components of the heart wall will replace this damage? A. *Proliferation of connective tissue cells B. Intracellular regeneration of contractive cardiac muscle cells C. Proliferation of contractive cardiac muscle cells D. Proliferation of conducting cells E. Proliferation of contractive cardiac muscle cells and conducting cells After myocardial infarction morphological structure of the heart wall was restored. At the expense of which tissue did regeneration occur? A. *Connective B. Smooth muscle C. Striated muscle D. Epithelial E. Nervous Large cells with light cytoplasm and eccentrically located nucleus are revealed in the histological specimen of the heart wall between endocardium and myocardium. What kind of heart cells have following morphologic signs? A. *Purkinje cells B. Pacemaker cells C. Cardiac muscle cells D. Endocrine cells E. Adipose cells In a heart specimen there are detected cells of squared shape, 80-120 micrometers in size, with a centrically positioned nucleus and well-developed myofibrils connected with the help of intercalated disks. What function is connected with these cells? A. *Heart contraction B. Nerve impulses conduction C. Endocrine D. Protective E. Regenerative Hematopoietic and immune defense organs Central lymphatic organs. During postembryonal hematopoiesis in the red bone marrow the cells of one of the cellular differons demonstrate a gradual decrease in cytoplasm basophilia as well as an increase in oxyphilia, the nucleus is being forced out. Such morphological changes are typical for the following haemopoiesis type: A *Erythropoiesis B Lymphopoiesis C Neutrophil cytopoiesis D Eosinophil cytopoiesis E Basophil cytopoiesis An electronic microphotograph shows a macrophagic cell with erythrocytes at different stages of differentiation located along its processes. This is the cell of the following organ: A *Red bone marrow B Thymus C Spleen D Tonsil E Lymph node A 46 year old patient was admitted to the hematological department. It was found that he had disorder of granulocytopoesis and thrombocytogenesis processes. In what organ does this pathological process take pace? A *Red bone marrow B Thymus C Spleen D Lymphatic ganglion E Palatine tonsil Medullary substance of a hemopoietic organ's lobule in a histological specimen is lighter coloured and contains epithelial bodies. What organ are these morphological preperties typical for? A *Thymus B Lymph node C Spleen D Liver E Kidney Patient has disordered processes of erythropoiesis, granulocytopoiesis, monocytopoiesis and thrombocytopoiesis. Which hematopoietic organ had been affected? A. *Red bone marrow B. Thymus C. Spleen D. Lymph node E. Tonsil During histological investigation of 40 years old man thymus was revealed decreasing of the thymus parenchyma, increasing of adipose and loose connective tissue, enriching of Hassall’s corpuscles while weight of the organ stay the same. What is the name of this phenomenon? A. *Age involution of the thymus B. Accidental involution of the thymus C. Thymus hypotrophy D. Thymus dystrophy E. Thymus atrophy In the slide of the human red bone marrow smear between myeloid row of cells and adipose cells one can find star shaped cells with oxyphilic cytoplasm which contacts with each other by means of their processes. Call these cells. A. *Reticular B. Fibroblasts C. Macrophages D. Dendrite cells E. Osteocytes The child was born with immunodeficiency. Cell mediated immunity has been affected that has caused often viral infections. Which organ has been damaged? A. *Thymus B. C. D. E. Red bone marrow Lymph node Spleen Tonsil A specimen of the human red bone marrow smear revealed accumulation of giant cells located near sinusoidal capillaries. Call formed elements of blood which formed from these cells. A. *Platelets B. Red blood cells C. White blood cells D. Lymphocytes E. Monocytes Under condition of experiment in the body of investigated animal was injected antibody against thymus hormones. Which cells differentiation will be affected first of all? A. *T lymphocytes B. Monocytes C. Plasma cells D. Macrophages E. B lymphocytes During infections and intoxication in the lobules of thymus amount of epithelioreticular cells and Hassall’s corpuscles are increased and area of medulla became larger. Give name of these changes in the thymus. A. *Accidental involution B. B immunodeficiency C. Thymico-lymphatic condition D. Age involution E. T immundeficiency In the experiment in the human red bone marrow ribosomes in the polychromatophilic erythroblasts were destroyed. Which specific protein synthesis will be disordered? A. *Globin B. Fibrinogen C. Collagen D. Elastan E. Laminine Slide of hematopoietic organ is under investigation. This organ consists of differently shaped lobules. In each of the lobule presents cortex and medulla. Which organ posses these morphological characteristics? A. *Thymus B. Lymph node C. Spleen D. Tonsils E. Appendix In the electron microphotograph one can see macrophage along processes of which situated erythrocytes at different stages of differentiation. What organ is it? A. *Red bone marrow B. Thymus C. Spleen D. Tonsil E. Lymph node In the slide one can see the organ stroma of which consists of reticular tissue, adipose cells, macrophages and osteogenic cells. What organ is represented in the slide? A. *Red bone marrow B. Spleen C. Thymus D. Lymph node E. Tonsil In the specimen one can see an organ which consists from lobules and stroma includes epitheliocytes with processes. What organ is represented in the slide? A. B. C. D. E. *Thymus Red bone marrow Spleen Tonsil Lymph node A 46 year old patient was admitted to the hematological department. It was found that he had disorder of granulocytopoiesis and thrombocytogenesis processes. In what organ does this pathological process take pace? A *Red bone marrow B Thymus C Spleen D Lymphatic ganglion E Palatine tonsil Medullary substance of a hemopoietic organ's lobule in a histological specimen is lighter colored and contains epithelial bodies. What organ are these morphological properties typical for? A *Thymus B Lymph node C Spleen D Liver E Kidney Hematopoietic and immune defense organs Secondary (peripheral) lymphatic organs In a histological specimen parenchyma of an organ is represented by lymphoid tissue that forms lymph nodes; the latter are arranged in a diffuse manner and enclose a central artery. What anatomic formation has such morphological structure? A *Spleen B Tonsil C Lymph node D Thymus E Red bone marrow Examination of a patient who was exposed to the ionizing radiation revealed damage of white pulp. What cells of white pulp undergo pathological changes? A *Lymphocytes B Neutrophilic leukocytes C Basophilic leukocytes D Monocytes E Tissue basophils A histological specimen presents an organ that has both cortical and medullary substance. Cortical substance consists of an external zone that contains lymph nodules as well as of a paracortical zone. Medullary substance contains medullary cords, sinuses and trabeculae. What organ possesses these morphological signs? A *Lymph node B Spleen C Kidney D Thymus E Adrenal glands In the slide which was made from the spleen one can see white and red pulp in the base of which is rest special tissue which formed their stroma. What tissue is it? A. *Reticular connective tissue B. Dense connective tissue C. Adipose tissue D. Muscle tissue E. Nervous tissue In the histological cross section of the lymph node in the experimental animal after antigen stimulation in the medullary cords one can find huge amount of cells with intensively basophilic cytoplasm, eccentrically positioned nucleus with chromatin giving the illusion of the spokes of the wheel and light area of cytoplasm near it. Call these cells. A. *Plasma cells B. Macrophages C. Fibroblasts D. Adipose cells E. Mast cells In the biopsy sample of the lymph node were revealed focuses of increased formation of plasma cells. Antigen depended stimulation of which immune cells have caused their formation? A. *B lymphocytes B. T lymphocytes C. Macrophages D. Dendrite cells E. Interdigital cells 15 years old patient during tonsillitis has enlarged his tonsils. Which histological structures of these organs take place in immune protection of the body as a response of streptococcus invasion? A. *Lymphatic nodules B. Stratified squamous keratinized epithelium C. Stratified squamous non keratinized epithelium D. Loose connective tissue E. Crypt In the specimen was revealed an organ in the reticular stroma of which situated blood formed elements and seen lymphoid formation. What organ is this? A. *Spleen B. C. D. E. Lymph node Tonsil Thymus Red bone marrow Student got 2 histological specimens. They both have lymphatic nodules. First slide has only follicles but second one has follicles with eccentrically positioned vessel. Determine these slides. A. *First-lymph node, second-spleen B. First-red bone marrow, second -spleen C. First thymus, second- spleen D. First liver, second -lymph node E. First-liver, second -spleen In a specimen was revealed roundish formation of the lymphocytes with a central artery in the center. What organ is it? A *Spleen B kidney C Lymph node D Thymus E Red bone marrow One has done histological section through lymph node. In the slide one can see enlargement of it paracortex. Proliferation of what cells of lymph node have caused this process? A. *T lymphocytes B. Dendritic cells C. Plasma cells D. Macrophages E. Reticular cells In a microscopic specimen is a bean-shaped organ which has cortical and medullar substance. Cortical substance is represented by separate spherical nodules 0,5-1 mm in diameter, medullar substance – by medullary cords. What organ is this? A. *Lymph node B. Kidney C. Thymus D. Adrenal gland E. Spleen In the specimen one can see an organ where lymphocytes formed 3 types of lymphoid structures such as lymphatic nodules, medullary cords and sinuses. What organ is it? A. *Lymph node B. Spleen C. Thymus D. Tonsil E. Red bone marrow Morphological investigation of the spleen revealed activation of immune reactions in the organism. In which structures of this organ do antigen depended proliferation of T lymphocytes begin? A. *Periarterial sheath of white pulp B. Central zone of white pulp C. Germinal center D. Marginal zone of white pulp E. Red pulp Hematopoietic and immune defense organs Intercellular communication in immune reactions To prevent epidemic of California virus vaccine (heterogenous protein) was injected in the organism of human. What cells will take place in specific immunity? A. *Lymphocytes B. Adipose cells C. Pigmentocytes D. Fibroblasts E. Adventitial cells A patient with clinical presentations of primary immunodeficiency displays disturbance of antigen-presenting function by immunocompetent cells. What cells may have structure defect? A *Macrophages, monocytes B T-lymphocytes C B-lymphocytes D Fibroblasts E 0-lymphocytes Burn wound was covered with pig skin (heterotransplantation). Call effector cells, which will rejected transplant (pig skin). A. *T killer B. T helper C. T suppressor D. B lymphocytes E. Natural killer 296. Plasma cell produces specific antibody for specific antigen. During injection of antigen quantity of plasma cell increased. At the expense of what blood cells occurred increasing of plasma cells quantity? A. *B lymphocytes B. Eosinophils C. Basophils D. T lymphocytes E. Monocytes Rejection of transplant developed in the patient after transplantation of heterogenous kidney. Call main effector cells, which take place in this immune reaction? A. *T killer B. B lymphocytes C. T suppressor D. T helper E. Plasma cells During heterotransplantation of the organ was revealed rejection of transplant. What blood cells will ensure this process? A. *T killer B. T helper C. T suppressor D. T 0 lymphocytes E. T memory cells Endocrine system. Hypothalamus and hypophysis The aim of the morphological study was to investigate an endocrine gland with parenchyma consisting of epithelium and neural tissue. In the epithelial trabeculae the study revealed two types of cells: chromophile and chromophobe. Identify this organ: A *Pituitary gland B Adrenal gland C Hypothalamus D Thyroid gland E Parathyroid gland A 32-year-old patient consulted a doctor about the absence of lactation after parturition. Such disorder might be explained by the deficit of the following hormone: A *Prolactin B Somatotropin C Vasopressin D Thyrocalcitonin E Glucagon Examination of a 32 year old patient revealed disproportional skeleton size, enlargement of superciliary arches, nose, lips, tongue, jaw bones, feet. What gland's function was disturbed? A *Hypophysis B Epiphysis C Pancreas D Thyroid E Suprarenal Patient K., 35 years old complains about permanent thirst, bad appetite. He drinks every day 9 L of fluid. Daily diuresis increased, urine discolored. Most probable reason of such pathology development in this patient is: A. *Hypothalamic nucleuses B. Epithelia of nephron tubules C. Adenohypophysis D. Pineal gland E. Basal membrane of glomerulus capillaries After sepsis 27 years old patient has bronze color of the skin which typical for Addison disease. Mechanism of hyper pigmentation based in increasing of hormone secretion. A. *Melanostimulating B. Somatotropic C. Gonadotropic D. B lipotropic E. thyreotropic Patient has suffered from hypothyroidism for 7 years. Deficiency of thyrotropic hormones was revealed. What cells of adenohypophysis will be changed? A. *Thyrotropes B. Gonadotropes C. Corticotropes D. Somatotropes E. Mammotropes On the background of deficiency of sex hormones in 30 years old female was revealed increased amount of follicle stimulating hormone. What cells synthesized this hormone? A. *Gonadotropes B. Thyrotropes C. Corticotropes D. Somatotropes E. Mammotropes In the specimen of adenohypophysis between endocrine cells one can see cells cytoplasm of which is stained oxyphilly. These cells secrete prolactin. Call these cells. A. *Mammotropes B. Thyrotropes C. Adrenocorticotropes D. Gonadotropes E. Pituicytes Cessation of bleeding after parturition connects with action of oxytocin to the uterus wall. Which layer of the organ does react at the action of this hormone? A. *Myometrium B. Endometrium C. Perimetrium D. Parametrium E. Submucous For morphological investigation endocrine gland was represented. Parenchyma of this gland consists of epithelium and nervous tissue. In epithelial trabeculae revealed two types of cells chromophiles and chromophobes. Name this organ. A. *Hypophysis B. Adrenal gland C. Hypothalamus D. Thyroid gland E. Parathyroid gland 40 years old woman has weak labor activity caused by weak contraction of myometrium. What hormone should be injected to help this woman? A. *Oxytocin B. Hydrocortisone C. Dexametasone D. Aldosterone E. Prednisolone Experimental animal produces big amount of urine and have strong thirst. Urine doesn’t have sugar. What cells disordered? A. *Neurosecretory cells of supraoptic nucleus B. Follicular endocrine cells of the thyroid gland C. Principal cells D. Endocrine cells of the zona glomerulosa of adrenal gland E. Endocrine cells of the medullary region of adrenal gland 50 years old patient complains about enlargement of ears, nose and hands size. Hyperfunction of which gland does these symptoms give? A. *Hypophysis B. Thyroid gland C. Sex glands D. Adrenal glands E. Pineal gland During X ray examination of the bones of the base of the cranium were revealed increasing of the cavity of sella turcica and thinning of processus clinoideus anterior and damaging of different areas of sella turcica. Tumor of what endocrine gland can cause such damaging of bones? A. *Hypophysis B. Thymus C. Pineal gland D. Thyroid gland E. Adrenal gland Endocrine system. Pineal gland. Adrenal gland. Microscopic examination of a parenchymatous organ revealed that its epithelial cords formed glomerular, fascicular and reticular zones. The central part of the organ was presented by accumulations of chromaffin cells. Specify this organ: A *Adrenal gland B Thyroid gland C Epiphysis D Liver E Hypophysis In a histological specimen of adrenal cortex there are petite polygonal cells that form roundish clusters and contain some lipid inclusions. What part of adrenal is presented in this histological specimen? A *Glomerulosa zone B Intermedial zone C Fasciculata zone D Reticularis zone E A patient has been given high doses of hydrocortisone for a long time. This caused atrophy of one of the adrenal cortex zones. Which zone is it? A *Fasciculata B Glomerulosa C Reticularis D Glomerulosa and reticularis E In the slide endocrine system organ is represented. It surrounded by connective tissue capsule which extends trabeculae in the center of the organ and formed lobules. Each lobule contains two types of cells Neurosecretory pinealocytes – polygonal cells with processes located in the center and glial cells (astrocytes) located in the periphery. What organ is this? A. *Pineal gland B. Hypophysis C. Hypothalamus D. Thyroid gland E. Medullary region of the adrenal gland Characterizing stress students made an inaccuracy by telling that synthesis of cortical region of adrenal gland glucocorticoids is stimulated by hypophysis hormones. What clarification should he make? A. *Adrenocorticotropic hormone B. Somatotropin C. Gonadotropic hormone D. Mammotropic hormone E. Thyrotropic hormone In the specimen parenchymal organ is represented. External layer of the cortex of it is formed by glomeruli created by endocrine cells. What organ is it? A. *Adrenal gland B. Lymph node C. Spleen D. Thyroid gland E. Ovary It is known that aldosterone regulates amount of sodium in the body. What cells of the adrenal gland do synthesize this hormone? A. *Cells of zona glomerulosa B. Chromaffin cells producing epinephrine C. Cells of zona reticularis D. Cells of zona fasciculata E. Chromaffin cells producing nor epinephrine Endocrine system. Thyroid gland. Parathyroid gland Parodontitis is treated with calcium preparations and a hormone that stimulates tooth mineralization and inhibits tissue resorption. What hormone is it? A *Calcitonin B Parathormone C Adrenalin D Aldosterone E Thyroxine A child has disturbed enamel and dentine formation as a result of decreased content of calcium ions in his blood. What hormone deficiency may cause such changes? A *Thyreocalcitonin B Somatotropin C Thyroxin D Parathormone E Triiodothyronine A patient has the sudden decrease of Са2+ content in blood. What hormone secretion will increase? A *Parathormone B Thyrocalcitonin C Aldosterone D Vasopressin E Somatotropin A child has abnormal formation of tooth enamel and dentin as a result of low concentration of calcium ions in blood. Such abnormalities might be caused by deficiency of the following hormone: A *Parathormone B Thyrocalcitonin C Thyroxin D Somatotropic hormone E Triiodothyronine Microscopic study of an endocrine gland revealed that its parenchyma consisted of follicular structures. Their wall was formed by monolayer cubic epithelium, and their cavity was filled up with oxyphilic substance. What hormone is secreted by this gland? A *Thyroxin B Aldosterone C Cortisol D Parathormone E Oxytocin A 9 y.o. boy was admitted to the endocrinological department. This boy has already had several fractures of wrist extremities due to bone brittleness. The function of the following endocrinal glands (gland) is disturbed: A *Parathyroid B Thyroid C Thymus D Adrenal E Epiphysis Clinical examination of a female patient revealed reduction of basal metabolism by 40%, gain in body mass, drop of body temperature, face puffiness, sexual dysfunctions, inertness and apathy, lowered intelligence. These symptoms are caused by dysfunction of the following endocrine gland: A *Hypofunction of thyroid gland B Hypofunction of parathyroid glands C Hypophysis hyperfunction D Epiphysis hypofunction E Hyperfunction of thyroid gland After a surgical procedure an experimental animal died from intense convulsions. What endocrinal glands were extracted? A *Parathyroid B Thyroid C Adrenal D Ovaries E Testicles Examination of a patient who complains about deglutitive problem revealed a tumor-like eminence 1-2 cm in diameter on the tongue root in the region of the cecal foramen. These are overgrown remnants of the following gland: A *Thyroid B Parathyroid C Adenohypophysis D Thymus E Sublingual Parodontitis is treated with calcium preparations and a hormone that stimulates tooth mineralization and inhibits tissue resorption. What hormone is it? A *Calcitonin B Parathormone C Adrenalin D Aldosterone E Thyroxin In the endocrine gland specimen one can see roundish structures varying sizes wall of which is formed with one layer of epithelial cells lying on the basal membrane. These structures contain homogeneous non cellular mass in the middle of them. What gland is it? A. *Thyroid gland B. Adrenal gland, cortex C. Parathyroid gland D. Anterior part of hypophysis E. Posterior part of hypophysis During inspection of patient oral cavity dentist noticed significant tremor of the tongue. Except it exophthalmos was present. Doctor suggested him to contact endocrinologist. During examination patient was diagnosed with Basedow’s disease. Hyperfunction of what cells caused this problem? A. *Follicular cells B. Parafollicular cells C. Principal cells D. Endocrine cells of adrenal gland zona glomerulosa E. Endocrine cells of adrenal gland zona fasciculata During operation by mistake in the patient endocrine gland was removed. It caused decreasing of the calcium blood level. What gland was removed? A. *Parathyroid B. Hypophysis C. Adrenal D. Thyroid E. Pineal During operation at thyroid gland two from four parathyroid glands were mistakenly removed. It caused decreasing of the calcium blood level. What cells are target for parathyroid gland hormone which increase level of calcium? A. *Osteoclasts B. Osteocytes C. Osteoblasts D. Fibroblasts E. Chondrocytes Two years old child has convulsions as a result of decreasing concentrations of calcium ions in the plasma. This is caused by declining function of: A. *Parathyroid glands B. Hypophysis C. Adrenal cortex D. Pineal gland E. Thymus Young woman comes to an endocrinologist with complains about sleepiness, depression, fatigue, bad appetite and increasing of the body weight. Disorder of what endocrine gland can cause such problems? A. B. C. D. E. *Thyroid Pancreas Adrenal cortex Adrenal medulla Ovary Under action of harmful factors of environment in follicular cells lysosomes formation disordered. What part of hormone production in the thyroid gland will be disordered? A. *Proteolysis of phagocytized colloid from follicles B. Colloid synthesis C. Iodination of colloid D. Resorption of colloid E. Thyroglobulin synthesis 40 years old patient came to a doctor with complains about tachycardia, exophthalmos, fatiguability, reduced weight of the body. Increasing of what cells functions does this condition connect? A. *Follicular cells B. Parafollicular cells C. Parathyroid cells D. Apud cells E. Acidophil endocrine cells 30 years old patient was diagnosed with thyroid gland hyperfunction. What shape do follicular cells have in the follicles? A. *Columnar B. Polygonal C. Squamous D. Spindle E. Cuboidal 42 years old patient after resection of thyroid gland had convulsions. After injection of calcium preparation she got relief. Disorder of what endocrine glands have caused this condition? A. *Parathyroid B. Adrenal C. Ovary D. Hypophysis E. Pineal Digestive system. Mouth. Tongue. Tonsils. There is a specimen of soft palate where both oral and nasal surfaces can be seen. It was revealed that oral cavity had damaged epithelium. What epithelium is damaged? A *Multistratal squamous nonkeratinizing B Multistratal cubical nonkeratinizing C Multistratal prismatic nonkeratinizing D Multistratal squamous keratinizing E Multirowed ciliated epithelium A child damaged the lateral surface of his tongue. What lingual papillas are most likely to be damged? A *Foliate B Conic C Vallate D Filiform E Fungiform A histological specimen of an oral cavity organ demonstrates that the organ's anterior surface is lined with multilayer squamous nonkeratinous epithelium, and its posterior surface - with multiserial ciliated epithelium. What organ is it? A *Soft palate B Gingiva C Hard palate D Lip E Cheek One of the structure of oral cavity has a few folds of mucous membrane in the lamina propria with numerous lymphoid follicles. What kind of organ is it? A *Tonsils B Tongue C parotid gland D Sublingual gland E submandibular gland The patient initiated a sense of taste. The overall sensitivity persists. Which papillae of the tongue are not damaged? A * Filiform B Circumvallate C Fungiform D Foliate E All A 53 years old patient complaining with the deterioration of taste sensitivity. During the examination doctor noticed the phenomenon of mucosal atrophy of certain areas of the mouth. Where are the most likely observed morphological changes? A * On the upper surface of the tongue B On the lower surface of the tongue C At the root of the tongue D On the hard palate E On the gums During an injury one of the areas of the mouth was damaged, it has maxillary, intermediate and mandibular area. Which organ was damaged? A * Cheek B Tongue C Lips D Hard palate E Soft palate In the biopsy of oral mucosa revealed morphological signs of the gums. What are the structural features of the mucous membrane of the gums can be observed in normal? A * Quiescent adherent to the periosteum, lamina propria forming high papillae, absent of muscular plate B Chubby adherent to the periosteum, well defined muscular plate C No muscular plate, submucosa is well-developed D No muscular plate and lamina propria E Contains many small salivary glands In histological slide were identify the part of the oral cavity, which is based on bone tissue. It is covered by mucous membrane, which shows stratified squamous epithelium. In the formation distinguish fat, glandular and marginal zone. In all areas of the lamina propria of mucosa collagen fibers form a powerful beam that intertwines in the periosteum. What kind of structure is represented in the sample? A * Hard palate B Gums C Lips D Cheek E Tongue In newborn baby was found median cleft lip and upper jaw. Abnormalities of which processes is caused this defect? A * Nonunion of the medial nasal processes. B Nonunion of the medial nasal processes of the maxilla. C Nonunion of the lateral nasal processes of the maxilla. D Cleft palatine processes. E Cleft maxillary processes. During the study of histological slides of oral mucosa was found that the stratified squamous epithelium infiltrated by lymphocytes. What is the area of the mouth is most likely represented in the sample? A * Mucous membrane of the tonsils B Mucous membrane of the lips C Mucous membrane of the cheek D Mucous membrane of the hard palate E Mucous membrane of the gums 351. In the study of histological preparations of the mouth shows that it has in its structure three parts: skin, mucous and intermediate parts. Basis of structure forms striated muscle. What is the structure of oral cavity? A * Lips B Hard palate C Soft palate D Tongue E Gums Dentist during examination of the oral cavity of the patient noticed that his tongue is covered with a whitish bloom. What histological structures involved in its formation? A * Epithelium of filiform papillae B Epithelium of foliate papillae C Epithelium of circumvallate papillae D Epithelium of fungiform papillae E Lingual tonsils The baby receives breast milk. What are the histological structure of oral cavity adapted for breast nipple stimulation causing reflex of milk? A * Epithelial villi of the lips B Keratinizing stratified squamous epithelium of the lips C Connective tissue papillae of the lips D Mushroom-shaped papillae of the tongue E Foliate papillae of the tongue In histological slides was defined structure of the oral cavity, represented by mucous membrane, which is free of attached and which is firmly adherent to the periosteum. Epithelium - stratified squamous keratinized. Lamina propria form long papillae deeply resort in the epithelium. What kind of structure is it? A *Gums B Hard palate C Lip D Cheek E Tongue In the newborn were found a defect in the sagittal line of the soft palate. Which process is displayed? A * Swallowing B Chewing C Digestion D Breathing E articulation In histological slide identified crypts of the tonsils, the epithelium is infiltrated by leukocytes. What kind of the epithelium is a part of this structure? A *Stratified squamous nonkeratinized. B Simple columnar. C Stratified cuboidal. D Stratified squamous keratinized. E Ciliated. The patient, 40 years old, suffering from heart attacks. A doctor appointed him receiving nitroglycerine under the tongue. What are the structural features of the mucous membrane of the mouth primarily determine the opportunity of medication? A *Permeability of the stratified squamous nonkeratinized epithelium B Permeability of the stratified squamous keratinized epithelium C Permeability of the stratified squamous epithelium D The presence of papillae of the tongue E The presence of salivary glands The patient, 30 years old, came to the doctor with complaints of fever up to thirty eight degrees, weakness, pain in the throat. The examination revealed that the patient's tongue is covered with white bloom. What are the histological structure of the tongue involved in the formation of plaque? A * Filiform papillae B Foliate papillae C Fungiform papillae D Circumvalate papillae E Connective tissue papillae of the tongue In the histological slide the head end of the embryo 5 weeks of determined gill arch. Indicate what develops from the first pair of data structures? A * Mandibular and maxillary processes. B Mandibular processes. C Maxillary processes. D The external auditory canal. E Thyroid cartilage. Excalation of which parts of the facial skull in the embryonic period leads to malformations such as "cleft palate"? A * Palatine processes B Frontal processes C Frontal and maxillary processes D Mandibular processes E Mandibular and palatine processes Digestive system. Salivary glands. A histological specimen of a mandibular gland shows an exctretory duct. Mucous membrane of the duct is lined with cubic epithelium whose cells have weakly developed organellas. What excretory duct is it? A *Intercalated B Striated C Interlobular D Common excretory E A microspecimen of parotid gland presents secretory acines with serous cells that synthesize mostly enzymes. According to the chemical composition classification, the parotid gland relates to the following glands: A *Serous B Mucous C Seromucous D Enzymatic E Examination of a microspecimen made of an unknown organ revealed some acini that contained 10-15 cone cells with basophilic cytoplasm, round nucleus and well developed granular endoplasmic reticulum. An acinus is surrounded by a basal membrane with myoepithelial cells localized in its splitting. What organ is the slice made of? A *Parotid gland B Pancreas C Lungs D Sublingual gland E Liver A microspecimen of the submandibular salivary gland shows some basket-shaped cells concentrated around the acines and excretory ducts. These cells surround bases of the serous cells and are called myoepitheliocytes. These cells relate to the following tissue: A *Muscular tissue B Epithelial tissue C Neural tissue D Special connective tissue E Loose fibrous connective tissue What substance makes the saliva viscous and mucous and performs protective function, including protection from mechanical injury of mouth mucous membrane? A *Mucin B Glucose C Kallikrein D Amylase E Lysozyme In course of embryogenesis maxillary and mandibular processes grew together with a delay. What development anomalies should be expected in this case? A *Macrostomia B Microstomia C Cleft palate D Gothic palate E Cleft of superior lip It is known that the submandibular salivary gland has a slimy end sections, consisting of mucocytes. What are the signs characteristic of these cells? A * Flattened nucleus and light cytoplasm B Basophilic cytoplasm C Rounded nucleus in the center of the cell D Microvilli E Basal striation Some diseases of the salivary glands caused by disruption of their excretory ducts. Which types are distinguished in the excretory ducts of salivary glands? A * Intra-, interlobular duct and common duct B Intralobular ducts, striated and common duct C Glistering, striated and common duct D Intra-, interlobular ducts E Intralobular ducts and outside the gland ducts In histological slide of the gland determined only serous end sections. In the interlobular connective tissue visible ducts, lined with double-layer or multilayered epithelium. Determine this structure. A * Parotid gland B Submandibular salivary gland C Pancreas D Sublingual salivary gland E Liver Digestive system. Teeth. In histological slide of mandibular tooth germ of embryo turns in which the dental papilla formed by small colored basophilic stellate cells. What tissue forms part of these dental germs? A * Mesenchyme B. Epithelial C Reticular D Cartilage E Bone On electronic microscopy of periodontal tissue fibers were found that one of their ends dipped in cement tooth root, and others - in the periosteum of the alveolar process. What kind of fibers they are? A * Sharpey fibers B Korff fibers C Ebner fibers D Purkinje fibers E Argyrophilic fibers On the histological slide were observed around the tooth periodontal thick bundles of collagen fibers that provide fixing the tooth in the dental alveoli. What are these fibers in the cervical area of the tooth? A * Circular B Oblique C Apical D Elastic E Myelinated On the histological slide of periodont were observed dense connective tissue composed of thick bundles of collagen fibers and provides a fastening tooth in the dental alveoli. This structurec has a special name: A * Dental fiber connections B Breakthrough fiber C Myelinated fibers D Korff fibers E Ebner fibers 42 years old patient, addressed to the dentist complaining of severe toothache. After examining the patient the doctor found inflammation of the dental pulp. What tissue forms the pulp of the tooth? A * Loose connective tissue B Amorphous dense fibrous connective tissue C Dense fibrous connective tissue framed D Reticular connective tissue E Mesenchyme To keep the tooth in the hole in the periodontal alveolar processes are bundles of collagen fibers that are arranged in different directions. How periodontal fibers oriented on the sides of the root? A * Obliquely B Vertical C Horizontal D Perpendicular E Circularly At the main part of the crown, neck and root of the tooth are present a dentin, whose length may increase with age, possibly as part of his recovery from injury. What structures provide these processes? A * Odontoblasts B Dentinal tubules C Perytubular dentin D Ameloblasts E Cementoblasts In the molars is visible a tissue, located at the upper part of the roots and in places of their branching. The tissue contains cells lying in lacunae and numerous collagen fibers with radial or longitudinal direction. Name this tissue. A * Cell cement B Reticular fibrous bone tissue C Dentin D Enamel E Dense connective tissue In the enamel on the edge of the dentin found non calcified areas that are often a place of infection in the tooth. How to call such structures? A * Enamel bundles B Enamel prisms C Enameloblasts D Dentynoblasts E Toms Fibers In histological slide, showing the histogenesis of tooth visible deposition of hydroxyapatite crystals in the form of globules. For what tooth characteristic this type of mineralization? A * Dentin B Enamels C Periodontal D Cement E Pulp The child complains of a toothache. Dentist stated carious enamel damage. Number of minerals which decreases in caries damage: A * Phosphorous, fluorine and calcium; B Sodium, calcium, potassium, C Potassium, phosphorus, fluorine; D Magnesium fluoride, calcium E Phosphorus, magnesium, potassium On histological slide grinding tooth enamel defined light and dark bands width 100 mm, directed radially. Identify the formation of enamel. A *Bands of Gunther Shreher B Lines of Retius C Perykimatiy D Enamel prisms E Enamel tufts In histological slides were found acellular cement. In which part of the tooth localized this tissue? A *On the lateral surface of the tooth root B On the surface of the crown C Forms a layer of coronal pulp D At the top of the tooth root E In the pulp canal During the examination of the patient was found abnormalities of enamel. With damage of what structural components of tooth germ is it occurs? A * Inner epithelium of enamel organ B Intermediate layer of the enamel organ C Pulp of enamel organ D Outer epithelium of enamel organ E Neck of enamel organ During the development of the primary tooth dentin tissue is laid. What is the source of its development? A * Dental papilla B Dental pouch C Tooth plate D Inner cells of the enamel organ E Outer cells of the enamel organ In the study of histological slides dental pulp was observed in the connective tissue dominated by bundles of collagen fibers odontoblasts layer thin intermediate layer is weak. In which area of the tooth pulp has the following features? A * Root pulp B Coronal pulp C Layer Weil D Peripheral layer of pulp E The central layer of pulp In the investigation of the chemical composition of dentin was found that in some areas it contains high content of minerals. Any damage to tooth decay much faster it breaks down, leading to the extension tubes and increasing the permeability of dentin. What type of dentin is it? A * Peritubular dentin B Interglodular dentin C Predentine D Mantle dentin E Circumpulpal dentin On histological slide grinding crown dentine in the intercellular substance is determined by a small number of collagen fibers (fibers of Korf) coming in the radial direction. Name this layer of dentin. A * Mantle dentine B Circumpulpal dentin. C Granular layer. D Interglobular dentin. E Predentine. In histological preparation grinding teeth is determined by cell-free tissue, consisting of intercellular substance pierced tubes, which are located in the cell processes. What structure is represented in the sample? A * Dentine. B Enamel. C Pulp. D Cement. E Dense connective tissue. Electron photomicrographs of transverse thin sections of tooth enamel lesions appear oval, polygonal or arched form, consisting of compacted and organized hydroxyapatite crystals. What is this formation A * Enamel prisms B Lines of Retius C Bands of Gunther - Shreher D Perykimatium. E Collagen fibers. In histological slide of tooth germ enamel organ outer surface is rough, the cells of the inner layer of cells occurred polarity (inversion nuclei). Determine the beginning of the process which preceded these changes. A * Enamelogenesis B Dentinogenesis C Pulpogenesis D Cementogenesis E Periodontal development On histological slide of the tooth in one of the tissues in the intercellular substance visible collagen fibers with radial and tangential direction. Decide for which tissue histogenesis is this a typical picture? A * Dentin B Enamel C Cementum D Pulp. E Dense connective tissue. On histological slide of the tooth is determined enamel organ in the form of "bell", which shows the external cube-shaped enamel cells, high internal prismatic cells and centrally located cells with processes that form a network. What is the period of tooth represented in the sample? A * During the formation and differentiation of dental germs. B Period bookmarks dental germs. C During the formation of the tissues of the tooth crown. D During the formation of the tissues of the tooth root. E Odontiasis period. In longitudinal grinding tooth dentin tubules seen. What is inside the tubules? A * Processes of dentynoblasts. B Processes of enameloblasts. C Body of dentynoblasts. D Fbroblasts. E Elastic fibers Before teeth come out first on their roots appears a solid tissue that looks like membrane reticulated bone. What tissue is it? A *Cement B Dentin C Enamel D Loose fibrous connective tissue E Dense fibrous connective tissue A histological specimen presenting a tooth slice shows that the intercellular dentin substance contains collagen fibers being tangential to the dentinoenamel junction and perpendicular to the dentinal tubules (Ebner's fibers). This dentin layer is called: A *Parapulpar dentin B Mantle dentin C Granular layer D Interglobular dentin E Secondary dentin Histological examination of trasverse enamel slice revealed linear banding in form of concentric circles that is pointing at an angle to the dentinoenamel junction. Name these structures: A *Retsius' lines B Hunter-Schreger's lines C Enamel plates D Enamel fascicles E Enamel spindles During the tooth development the enamel organ has prismatic cells with hexagonal intersection; the nucleus is situated in the central part of the cell. What cells are meant? A *Preenameloblasts B Exterior enameloblasts C Cambial cells D Enamel pulp cells E Preodontoblasts During the embryogenesis of oral cavity the development of dental enamel was disturbed. What source of dental development was damaged? A *Epithelium B Mesenchyma C Mesoderma D Dental saccule E Dental papilla Examination of a tooth slice of a 42 y.o. man revealed on the dentinal-enamel border some solid linear fusiform structures as long as 1/3 of enamel depth. What structures were revealed? A *Enamel spindles B Denticles C Enamel fascicles D "Dead" tracts E Carious damage A histological specimen of mandible of an embryo shows a tooth germ with the dental papilla made up of small stellate basophilic cells. What tissue forms this part of the tooth germ? A *Mesenchyme B Epithelial C Reticular D Cartilaginous E Osseous Examination of a 42-year-old patient suffering from paradontosis revealed some roundish calcified formations 2-3 mm in diameter in the coronal pulp. Name these structures: A *Denticles B Interglobular dentin C Interglobular spaces D Sclerotic dentin E Dead dentin A histological specimen presents a developed tooth that has a coating resistant to acids, but it can be found only on the lateral surfaces of the tooth. What coating is meant? A *Cuticle B Dentine C Enamel pellicle D Enamel E Cement Histological study of an extirpated pulp revealed some cylindrical cells in its peripheral layer. What are these cells called? A *Odontoblasts B Fibroblasts C Monocytes D Ameloblasts E Myofibroblasts In the process of tooth tissue histogenesis dentin wasn't formed in time for some reasons. What process of further histogenesis will be delayed or will not take place at all? A *Enamel formation B Pulp formation C Predentinal space formation D Cellular cement formation E Acellular cement formation In animal experiments the dental germs destroyed the inner layer of the epithelium of the enamel organ. Development of which tooth is broken? A * Enamel B Dentine C Cementum D Pulp E Periodontal ligament Digestive system. Pharynx. Esophagus. A patient underwent gastroscopy that revealed insufficient amount of mucus covering the mucous membrane. This phenomenon is caused by the dysfunction of the following cells of stomach wall: A *Cells of prysmatic glandular epithelium B Parietal cells of gastric glands C Principal exocrinocytes of gastric glands D Cervical cells of gastric glands E Endocrinocytes The 60 years old patient is suffering from chronic gastritis. At the endoscopy of the stomach observed changes in the epithelium of the mucosa. Which type of epithelium covers of the stomach mucosa? A * Simple columnar mucous epithelium B Pseudostratified ciliated columnar epithelium C Smple squamous epithelium D Simple cuboidal epithelium E Simple columnar brush-border epithelium The patients with burnings of the esophagus was examined by the doctor and found that lesions of the mucous membrane are not deep. Due to which layer of cells will take place regeneration of damaged epithelium. A * Basal B Spinous C Grained D Intermediate E Surface On histological slide represented a cross section of a hollow organ wall, which has a mucous membrane consist of nonkeratinized stratified epithelium. What kind of structure is it? A * Esophagus B Duodenum C Colon D Uterus E Appendix On microscopic examination were presented striated muscle tissue of the digestive system. In what kind of organ the biopsy was taken? A * Esophagus B Stomach C Duodenum D Ileum E Appendix Digestive system. Stomach. On the electronic microphotographs of fundic glands were determined a large, pale and round to pyramidal cells. They have one or 2 central nuclei and acidophilic cytoplasm. The many mitochondria indicate that their secretory activity is energydependent. What kind of cell they are? A * Parietal (oxyntic) cells B Mucous neck cells C Undifferentiated cells D Enteroendocrine cells E Chief cells Insulin injection did for assess the completeness of vagotomy accompanied by a significant increase of ph of gastric juice. Which cells of gastric glands controls this process? A * Parietal cells B Enteroendocrine cells C Chief cells D Mucous neck cells E Undifferentiated cells On the histological sections of fundic glands we can see as large cells with acidophilic cytoplasm. What kind of component of gastric juice is produced as a result of the activity of these cells? A * Hydrochloric acid B Pepsinogen C Mucus D Serotonin E Gastrin Under the action of harmful factors occurred local damage of the epithelium of the stomach. What kind of cell can provide regeneration process? A * Mucous neck cells B Parietal cells C Chief cells D Enteroendocrine cells E Mucocytes The 20 years old patient suffers from rheumatism appointed of prolonged use of aspirin. What is the structural component of the mucous membrane of the stomach is best suited to provide her protection from damage? A * Simple columnar mucous epithelium B Connective tissue C Muscle tissue D Multi-ciliated epithelium E Stratified squamous nonkeratinized epithelium The patient biopsy from the stomach shows histologically revealed a significant reduction or complete absence of parietal cells in the glands. Which layer of mucous membrane they studied? A * Pylorus B Fundus of stomach C Cardiac part D Body of stomach E– In 42 years old patient after radiotherapy of cancer of the stomach developed pernicious anemia due to damage cells by producing intrinsic factor. Which cells of fundic glands were damaged? A * Parietal cells B Mucous neck cells C Surface mucous cells D Enteroendocrine cells E Chief cells In the embryonic material was damaged endoderm. What kind of changes of development may arise in this process? A * Stomach B Heart C Kidneys D Aorta E Salivary glands Damaged by exposure to various factors of gastric mucosa can restore its integrity. By which cells of gastric glands can occur their regeneration? A * Mucous neck cells B Parietal cells C Paneth cells D Chief cells E Enteroendocrine cells By ingestion of a foreign body in the stomach was damaged epithelium of the child. How the cell regeneration process possible? A * Mucous neck cells B Chief cells C Parietal cells D Connective tissue cells E Fat cells During the fibrogastroscopy of the patient revealed damage of the mucosa layer. By which cells will occur in the treatment of epithelial regeneration? A * Poorly differentiated mucous neck cells B Chief cells C Parietal cells D Enteroendocrine cells E Paneth cells During inflammatory diseases of the stomach damaged surface epithelium of the gastric mucosa. What kind of epithelium was damaged? A * Simple columnar mucous epithelium B Stratified squamous nonkeratinized epithelium C Stratified squamous keratinized epithelium D Simple cuboidal epithelium E Stratified cuboidal epithelium Analysis of biopsy material of human gastric mucosa, gastritis patient showed a dramatic decrease in the number of parietal cells. How will change the components of gastric juice? A * Reduce acidity B Increased acidity C Increased gastric juice D Reduction of gastric juice E Reducing mucus production Examination of a patient, suffering from atrophic gastritis, revealed megaloblastic anemia. The anemia is likely to be caused by the deficiency of the following substance: A *Gastromucoproteid B Vitamin B6 C Vitamin B1 D Iron E Erythropoietins A patient underwent gastroscopy that revealed insufficient amount of mucus covering the mucous membrane. This phenomenon is caused by the dysfunction of the following cells of stomach wall: A *Cells of prysmatic glandular epithelium B Parietal cells of gastric glands C Principal exocrinocytes of gastric glands D Cervical cells of gastric glands E Endocrinocytes During the examination of the patient's oral cavity dentist noticed that his tongue is rough hypertrophic nipples, deep furrows. The doctor advised the patient to consult a gastroenterologist. The examination revealed that he had considerably increased acidity of gastric juice. Hyperfunction of which cells in the glands of the mucous membrane of the stomach mainly caused this condition? A * Parietal cells of fundic glands B Chief cells C Additional mucocytes D Goblet cells E Exocrine pancreatocytes The 60 years old patient is suffering from chronic gastritis. During an endoscopy of the stomach observed changes in the epithelium of the mucosa. What epithelium has undergone a change? A * Simple columnar mucous epithelium B Connective tissue C Muscle tissue D Multi-ciliated epithelium E Stratified squamous nonkeratinized epithelium Digestive system. Small and large intestine. In some diseases of the colon change correlation of number between epithelial cells of the mucosa. What types of cells predominate in the epithelium of the crypts of the colon normally? A * Goblet cells B Columnar villous epithelial cells C Endocrinocytes D Cells with acidophilic granules E Undifferentiated cells Some diseases of the small intestine associated with dysfunction of exocrynocytes with acidophilic granules (Paneth cells). Where are these cells located? A * At the bottom of intestinal crypts B On the apical side of intestinal villi C On the sides of the intestinal villi D In place of transition in villus crypt E In the upper part of the intestinal crypts During endoscopic examination of the patients with chronic enterocolitis (inflammation of the colon), there is no specific structures reliefs of the small intestine. What components determine the relief features of the mucous membrane of this organ? A * Circular folds, villi and crypts B Felds, folds, holes C Haustry, villi, crypt D Oblique folds E Villi During the examination of the patients with diseases of the small intestine revealed disruption of the wall and membrane digestion. With dysfunction of what kind of cells it is connecting? A * Column with border B Column without border C Goblet D Paneth cells E Endocrinocytes During the diseases of the mucosa layer of the small intestine suffers absorption function. What kind of epithelium is responsible for this function? A * Simple columnar epithelium B Simple cuboidal C Simple columnar D Stratified squamous epithelium E Stratified cuboidal The student had a histological slide of the small intestine submucosa in which the foundation has a large number of glands. Which part of the small intestine is it? A * Duodenum B Jejunum C Ileum D Ascending colon E Descending colon On the electronic microphotogram of crypts of the small intestine can be identified some cells. They lying in the bases of the crypts, have many large acidofilic secretory granules. What is the name of these cells? A * Paneth cells B Enterocytes C Goblet cells D Undifferentiated cells E Enteroendocrine cells On a histological specimen of the small intestine in the lamina propria of mucosa revealed clumps of cells spherical shape with large basophilic nuclei surrounded by a narrow rim of cytoplasm. In most of the central part of the light clusters and contains fewer cells than peripheral. Which is the morphological structure of such clusters? A * Lymphatic nodule B Nerve bundle C Fat cells D Blood vessels E Lymphatic vessels On a histological specimen of submucosa of the small intestine is filled of endings of the protein secretory glands. Where was the section of intestine done which is presented in the sample? A * Duodenum B Jejunum C Cecum D Ileum E Appendix In the cytoplasm of epithelial cells of the colon’s crypts were found dypeptydase and lysozyme. What kind of cells can produce these enzymes? A * Paneth cells B Columnar epithelial cells C Goblet cells D A-cells E S-cells On a histological specimen of a wall of the digestive system in the lamina propria of the mucosa and submucosa were found numerous lymphoid nodules. Name the structure. A *Appendix B Stomach C Duodenum D Ileum E Colon During a biopsy investigation of the wall of the small intestine has been taken out the part of mucosa layer. What epithelium covers the mucosal surface of the organ? A * Simple columnar epithelium with goblet cells B Stratified squamous nonkeratinized epithelium C Stratified squamous keratinized epithelium D Simple cuboidal epithelium E Stratified cuboidal epithelium Digestive system. Liver. An electron micrograph of internally lobed liver sinusoid represented cells, which can be seen in the cytoplasm granules with a seal like fruit pit. We know that this is a natural killer cell. Which cell is represented. A * Pit-cell B Hepatocytes C Endothelial cells of sinusoid D Kupfer cells E Fat-storing cell In the patient from therapeutic department with severe liver pathology revealed violations of coagulation. What is the function of the liver can be affected in this case? A * Protein Synthesis B Detoxication C Endocrine D Protective E Bile formation During proliferation of connective tissue in parenchyma of the liver (fibrosis) due to chronic diseases there is disruption of blood circulation in classic liver lobule. What is the direction of blood flow in these structures? A * From the periphery to the center B From the center to the periphery C Around lobule D From the top to the bottom E From the bottom to the top An examination of the patient revealed abnormalities of the liver. Which embryonic germ layers have been damaged? A * Endoderm middle sections of primary colon B Endoderm posterior wall C Foregut endoderm D Mesonephritic duct E Hindgut endoderm As a result of stab wounds in the liver was damaged the hepatic artery, but the liver lobule blood continued to flow. Which vessel provided blood flow in lobules? A * Interlobular vein B Interlobular artery C Portal vein D Sublobular vein E Hepatic vein In histological slide of parenchyma of the organ slices is presented, the shape is hexagonal prisms and consist of anastomosing plates between which are sinusoidal capillaries that converge radially to the central vein. What is the anatomical organ has given morphological structure? A * Liver B Pancreas C Thymus D Spleen E Lymph node During carbohydrate over-feeding of the animals in the cells of the liver we can find histologically a large amount of glycogen granules. What group of cell structures includes glycogen? A * Trophic inclusion B Secretory inclusion C Excretory inclusion D Pigment inclusion E Organelles with special functions As a result of hepatotrophic poisons in hepatocytes was destroyed granular EPR. Synthesis of which components will be change in the epithelium of the liver? A * Albumin and fibrinogen B Phospholipids C Glycogen D Cholesterol E Vitamins Digestive system. Pancreas. A 50 years old patient complains with increased appetite, thirst, decreased body weight, weakness and fatigue. During laboratory examination revealed increase the amount of sugar in the blood. Which cells dysfunctions are associated with the development of this disease? A * B cells B A -cell C Thyrocytes D Pankreatocytes E Lipotropocytes In histological slide were studied exocrine portion of the pancreas. In the cells of the exocrine parenchyma contained secretory granules with enzymes. How do they come (these enzymes) to the digestive tract? A * Through duct system B Through the bloodstream C Fall into the lymph D Aхonic transport E Dendritic transport During the study of pancreatic cells plasmolemma after exposure to drugs offenses were discovered in the structure of the glycocalyx. What are the chemical components of the glycocalyx is composed of cells of the pancreas? A * Oligosaccharides B Proteins C Lipids D Mineral salts E Water In the histological slide of the pancreas we can find a group of cells. Some of them are centrally located and has basophilic secretory granules. Their secret regulates carbohydrate metabolism. What kind of cells they are? A * B cells B PP cells C A cells D Adipocytes E D cells Respiratory System Premature infants have syndrom of respiratory failure. Failure of what aerohematic barriere component underlies this pathology? A *Surfactant B Capillary endothelium C Basal membrane of endothelium D Basal membrane of alveolocytes E Alveolocytes A patient with an acute rhinitis has hyperemia and excessive mucus formation in nasal cavity. What epithelial cells of mucous membrane have the intensified activity? A *Goblet cells B Ciliated cells C Microvillous cells D Basal cells E Endocrine cells A patient was admitted to the hospital with an asphyxia attack provoked by a spasm of smooth muscles of the respiratory tracts. This attack was mainly caused by alterations in the following parts of the airways: A *Small bronchi B Median bronchi C Large bronchi D Terminal bronchioles E Respiratory part During dissection (autopsy) of the 65 years old man, who suffered from lung disease pathological process was mainly localized in the bronchi, where during the histological examination were clearly visible glands, cartilage islands and pseudostratified epithelium. Which bronchi were changes? A * Secondary bronchi B Primary bronchi C Tertiary bronchi D Bronchioles E Terminal bronchioles In electronic microphotograph were detected cells of the alveoli, which are part of the blood-air-barrier (aero-hematic barrier). What are these cells? A * Respiratory epithelial cells of the alveoli B secretory epithelial cells of the alveoli C Alveolar macrophages D Clara cells E Ciliated epithelial In 66 years old man was diagnosed a malignant epithelial tumor, originating from the medium-sized (secondary) bronchi. What epithelium is the source of this tumor? A *Pseudostratifed B Stratified squamous nonkeratinized C Stratified squamous keratinized D Simple columnar E Transitional In the preterm baby were found sticking walls of the alveoli due to lack of surfactant. Please indicate dysfunction of which cells of the wall of alveoli causes this condition. A * Alveolocytes type II B Fibroblasts C Alveolocytes type I D Alveolar macrophages E Secretory Clara cells In the alveoli of the lungs are present special cells through which gas exchange, they are part of the aero-hematic barrier. What are these cells? A * Alveolocytes I type B Clara cells C Alveolar macrophages D Alveolocytes II type E Epitheliocytes with microvilli As a result of trauma 30 years old man’s nose damaged mucous membrane that covers the upper part of the nasal cavity. What will be the result, what it led to? A * Smperception odorous substances B Violation of humidification C Violation of secretory activity of goblet cells D Violation of warm air E Violation of warming and humidification The patient has an inflammation process in the trachea, which captures the epithelium and lamina propria of the mucosa. What epithelium has undergone a change? A * Single layer ciliated B Stratified squamous nonkeratinized C Stratified cuboidal D Transitional E Simple cuboidal In the biopsy of the mucosa of patients with bronchial asthma revealed a significant number of cells with multiple metachromatic granules. Name this cell? A * Tissue basophils B Macrophages C plasma cells D reticulocytes E fibroblasts Study of a tubular organ revealed that its median membrane consists of solid hyaline rings. What epithelium lines mucous membrane of this organ? A *Multinuclear prismatic ciliated B Monostratal prismatic glandular C Monostratal prismatic with a border D Multistratal squamous nonkeratinizing E Monostratal cubical In the chemical industry workers after inhalation of corrosive vapors death occurred in ciliated epithelial cells of the bronchi. How the cells of the epithelium regeneration take place? A * Basal cell B Goblet cells C Endocrine cells D Ciliated cells E cilia-free cells (Clara cells) In the airway epithelium are present dome-shaped cilia-free cells, which are placed on the surface of microvilli. There cytoplasm contains glycogen granules, lateral and apical Golgi complexes, elongated mitochondria, and a few secretory granules. What is the name of these cells? A * Clara cells B Goblet cells C Endocrine cells D Cells without border E Cambial cells In histological slide of the trachea are muco-ciliary comprising low cells have oval or triangular shape. Their tops they reach epithelial apical surface, in some cells occurs mitosis. What function do these cells? A * Is a source of regeneration. B Part of the muco-ciliary complex. C Secretes mucus. D Secretes surfactant. E Producing biologically active substances. After a prolonged inflammation of the mucous membrane of the nasal cavity of a patient observed changes in the epithelium. What epithelium has undergone a change? A * Simple pseudostratified B Simple squamous C Stratified squamous D Stratified cuboidal E Stratified columnar Urinary system A female patient with pyelonephritis was admitted to the urological department. Examination revealed an associated infection accompanied by pyelovenous reflux. This complication was induced by affection of the following structure: A *Fornical renal apparatus B Excretory renal tracts C Straight tubules D Renal tubules E Renal corpuscle In course of an experiment the blood pressure of an animal had a stable rise by means of renal artery constriction. Hyperfunctioning of what renal cells cause this effect? A *Juxtaglomerular cells B Podocytes C Endotheliocytes D Interstitial cells E Thick spot cells Electron micrograph of a kidney fragment presents an afferent arteriole with big cells under endothelium. These cells contain secretory granules. Name this type of cells: A *Juxtaglomerular B Mesangial C Smooth muscular D Juxtavascular E Interstitial A histological specimen of a kidney shows a part of the distal tubule going between the afferent and efferent arteriole. The cells building the tubule wall have dense nuclei; basal membrane is absent. Such structural formation is called: A *Macula densa B Juxtaglomerular cells C Mesangial cells D Juxtavascular cells E A microphotography represents a fragment of cortical substance of a kidney. This fragment contains thick spot cells and juxtaglomerular cells with big secretory granules. What kidney structure is represented? A *Juxtaglomerular apparatus B Renal corpuscle C Filtering barrier D Prostaglandin apparatus E Choroid glomus Electron-microscope investigation of cortical substance of a kidney reveals some structures lined with prismatic epithelium that normally has brush border and deep plicae of plasmolemma in its basal part. There is a big number of mitochondrions between these plicae. These structures belong to the following part of a nephron: A *Proximal tubule B Distal convoluted tubule C Henle's loop D Renal corpuscle E Distal straight tubule A patient ill with chronic glomerulonephritis has a disturbed incretory function of kidneys. It will result in the deficit of the following blood corpuscles: A *Erythrocytes B Leukocytes C Thrombocytes D Leukocytes and thrombocytes E Erythrocytes and leukocytes In patients with chronic pyelonephritis there is no acidification of urine, so it is no bactericidal. Which structures of the kidney injury occurred? A * Dark cells of the collecting tubules B In the glomeruli C In podocytes capsules D In the proximal convoluted tubules E In the distal tubules Malformations of the urinary system occur, according to statistics, 10-14% of infants. What are the sources of the development of the urinary system? A * Nonsegmental caudal mesoderm B Dorsal mesoderm C Visceral leaf of ventral mesoderm D Parietal leaf of ventral mesoderm E Germ mesenchyme The patient was suffered from edema (swelling). A large amount of protein present in urine. About dysfunction of which part of nephron does it mean? A * Renal corpuscle B Proximal convoluted tubule C Distal convoluted tubule D Downturn of the loop of Henle E Ascending part of the loop of Henle Urine was taken from 17 year old young man from a bladder using the catheter. Which epithelial cells of the urinary bladder can be detected by microscopy? A * Transitional B Stratified nonkeratinized C Simple columnar D Simple cuboidal E Stratified keratinized Microscopic study of kidney biopsies found in its cortex tubules about 60 microns in diameter; their wall is formed by a high cuboidal epithelium with abundant long microvilli. What structure is it? A * Proximal tubules B Distal tubules C Capsule kidney cells D Team rolls E Loop of Henle In histological slide of renal cortex can be seen renal corpuscles and tubules of nephrons. It is known that in the tubules of the nephron reabsorption occurs. Which tissue of the nephron involved in this process ? A * Epithelial B Connective proper C Reticular D Mucous E Cartilaginous An important part of the renal filtration barrier is a three-layer basement membrane, which has a special network structure of the middle layer. Where is this basement membrane? A * In the renal corpuscles B In capillaries of the perytubular capillary network C In the proximal tubules D In the small tubules E In the distal tubules live During the clinical examination in 35 -year-old women with kidney disease identified in urine blood cells, fibrinogen, which is likely due to the renal filter. Which structures are composed this filter? A * Endothelium of the capillaries of the glomerulus, three-layer basement membrane, podocytes B Three basement membrane C Endothelium of the capillaries, the basement membrane D Podocytes, the basement membrane E Endothelium, podocytes In electron microscopy revealed the kidney tubules, which are lined by cuboidal epithelium. In the epithelium distinguish light and dark cells. Light cells had organelles. These cells provide the reabsorption of water from primary urine in the blood. Dark cells in structure and function resemble parietal cells of the stomach. What tubules represented in microscopic slide? A *Collecting ducts B Proximal convoluted tubules C Distal tubules D Ascending part of the loop of Henle E Descending part of the loop of Henle Male reproductive system One of the phases of spermatogenesis observed changes in the nucleus and cytoplasm of spermatids, leading to the formation of mature gametes. What phase of gametogenesis is it? A * Formation. B Maturation. C Growth D Reproduction E Proliferation In testes destructive changes observed in cells of seminiferous epithelium, which are already in the stage of formation spermatids and spermatozoa. By which cells can restore spermatogenesis? A * Spermatogonia B Primary spermatocytes C Secondary spermatocytes D Supporting cells E Leydig cells In histological slide of the testes in layers of connective tissue between the seminiferous tubules occur as vascular nests of pale acidophilic cells with well-developed smooth endoplasmic reticulum, Golgi complex and mitochondria. What kind of cells they are? A * Interstitial cells B Supporting cells C Myoid cells D Fibroblasts E Spermatogonia During puberty, the cells of male gonads begin producing the male sex hormone testosterone, which causes the appearance of secondary sex characteristics. Which cells of male gonads produce this hormone? A * Leydig cells B Sustentocytes C Sertoli cells D Supporting cells E Spermatozoa Female reproductive system. A patient underwent Caesarean section. During the operation a long incision was made in the uterus wall and the fetus was extracted from uterus. Healing of the sutured myometrium will proceed in the following way: A *Formation of a fibrous cicatrix B Formation of smooth muscular tissue C Formation of cross-striated muscle fibers D Proliferation of myosatellitocytes E Hypertrophy of smooth myocytes A 35 y.o. patient diagnosed with sterility came to gynaecological department for diagnostic biopsy of endometrium. Microscopic examination revealed that mucous membrane is edematous, uterine glands are convoluted and filled with thick secreta. Such changes in the endometrium are caused by excess of the following hormon: A *Progesterone B Estrogen C Testosterone D Somatotropin E ACTH In the histological slide of the ovary, stained with hematoxylin-eosin, were identified a follicle in which follicular epithelial cells located in 1-2 layers and have a cuboidal shape, around the oocyte membrane is visible bright red color. What is the name of this follicle? A * Primary B Primordial C Secondary D Mature (Graafian) E Atretic Normal human embryo implantation can occur only with the corresponding changes of endometrium. Which cells of endometrium will increase during this process? A * Decidual cells B Macrophages C Endothelial cells D Fibroblasts E Neurons In the cortex of the ovary histological examination determined mature tertiary follicle. In which period of oogenesis they were formed? A * Stage of great growth B Stage of small growth. C Maturation. D Reproduction. E Formation. For early diagnosis of pregnancy in women using their urine. The presence of which hormones would likely indicate a pregnancy? A * Chorionic gonadotropin B Estriol. C Aldosterone. D Testosterone. E Progesterone. As a result of inflammation in the fallopian tubes the moving of zygote was difficult. What type of epithelium was changed? A * Simple columnar ciliated B Stratified squamous nonkeratinized C Pseudostratified D Simple cuboidal E Stratified squamous keratinized 496. Microscopic examination of the ovary, which was removed during operation were detected primordial and primary follicles and corpus luteum in the stage of prosperity. In what kind of stage of ovarian-menstrual cycle are the female reproductive organs with these structural features of the ovary? A *Premenstrual B Menstrual C Preovulatory D Postmenstrual E Ovulatory The 35 years old patient, diagnosed with infertility in the gynecological department, diagnostic endometrial biopsy was done. Microscopic examination revealed that the mucosa with edema, uterine glands are meandering, filled with thick secret. What hormone causes the following changes in the endometrium? A * Progesterone B Estrogen C Testosterone D Somatotropin E ACTH Stop bleeding after childbirth is associated with the action of hormones on the structures of the uterus. Which component of the uterine wall takes part in this most of all? A * Middle layer of myometrium B Endometrium C The inner layer of the myometrium D The surface layer of the myometrium E Perimetrium Histology of the endometrium is characterized by the following features: thickening, edema, presence of tortuous glands with enlarged lumen that secrete large amounts of mucus, mitosis in cells not observed, in stroma are available decidual cells. What is the stage of the menstrual cycle corresponds to the described picture? A * Secretory (premenstrual or luteal). B Menstrual C Regenerative D Proliferative E Relative calm Microscopic examination of the female internal reproductive organs, which were removed during operation was found an embryo constructed of two blastomeres. Name the place of its location in case of normal development. A *Fallopian tubes, close to the ampulla B Fallopian tubes, close to the uterus C The cavity of the uterus D Abdomen E Ovary By producing a number of hormones placenta plays a part of temporary endocrine gland. What hormone may be detected in woman's blood on the 3rd or the 4th day after begin of implantation, that is used in medicine for early pregnancy detection? A *Chorionic gonadotropin B Somatostatin C Progesterone D Vasopressin E Oxytocin At 40 years old woman weak labor associated with weak contractility of the myometrium. What do you need to inject for the help? A *Oxytocin B Hydrocortisone C Dexamethasone D Aldosterone E Prednisone In ovarian-menstrual cycle changes occur endometrial glands. glands? A *Simple unbranched tubular B Simple branched tubular C Simple unbranched alveolar D Alveolar unbranched E Alveolar-tubular branching Which of the following types are appointed endometrium In histological slide of the ovary presented rounded structure, glandular cells of which contain lipid droplets. Identify this structure. A * Yellow body B Primordial follicles C Primary follicle D Mature follicle E Atretic body Stop bleeding after childbirth is due to the action of oxytocin on the uterus wall. Which layer of the uterus reacts to the action of this drug? A * Myometrium B Endometrium C Perimetrium D Parametrium E Submucosa