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A. Increased cardiac output and venous return in dynamic exercise. The sympathetic nervous system activation increases ventricular contractility,
producing a left shift in the cardiac function curve. Venoconstriction causes a right shift in the vascular function curve, with increased mean circulatory
filling pressure and venous return. Vasodilatation in working muscle causes systemic vascular resistance to decrease, increasing the slope of the venous
return curve. A new operating point at higher venous return and cardiac output is achieved. B. Cardiac output and venous return in compensated heart
failure. Decreased ventricular performance causes a right shift in the cardiac function curve. Mean circulatory filling pressure is increased by fluid retention
but venous return is restricted by increased systemic vascular resistance. Cardiac output and venous return are almost maintained in this patient, but at
Source: Cardiovascular Physiology, Medical Physiology: The Big Picture
the cost of high right atrial pressure.
Citation: Kibble JD, Halsey CR. Medical Physiology: The Big Picture; 2015 Available at: http://mhmedical.com/ Accessed: May 07, 2017
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