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GUIDED NOTES-PROTEIN STRUCTURE Shape of a protein determines what? What happens if proteins shaped is changed? What is denaturation? What can cause denaturation of a protein? What are the four levels of organization of a protein? What is primary structure? What information does primary structure provide? An example of changing one amino acid in chain that causes a disease is? What is secondary structure? What are the two types of secondary structure? What bonds and between what holds secondary structure together? What is tertiary structure? What bonds and between what holds tertiary structure? What is quaternary structure? Do all proteins have quaternary structure?