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NHANES: A Potential Database for
Risk Assessment
Clifford Johnson
Centers for Disease Control and Prevention
National Center for Health Statistics
National Health and Nutrition
Examination Survey (NHANES)
Objective
To assess the health and nutritional
status of adults and children in the
United States
OP96S022
National Health and Nutrition
Examination Surveys
Survey
NHES I
NHES II
NHES III
NHANES I
NHANES II
HHANES
NHANES III
NHANES
Dates
1960-62
1963-65
1966-70
1971-75
1976-80
1982-84
1988-94
1999-
Ages
18-79 years
6-11 years
12-17 years
1-74 years
6 mo.-74 years
6 mo.-74 years
2 mo. +
All ages
OP96S025
NHANES sample design
•
Continuous data collection beginning in 1999
•
Multi-stage probability sample
•
Annual national sample of 5,000 persons
•
Detailed estimates of population subgroups
requires two or more years
NHANES process
Identification of sample persons
Interview
Mobile
Examination
Center
Home
Examination
Longitudinal Followup
OP96S028
NHANES household interview
•
Broad range of health conditions
•
Health care coverage and need
•
Environmental and occupational
exposures
•
Health behaviors
•
Nutrition and dietary supplements
OP96S039
NHANES Mobile Exam Center
NHANES topics
•
•
•
•
•
•
•
Cardiovascular disease
Diabetes, lower extremity disease
Bone status, osteoporosis
Oral health
Vision
Hearing and balance
Fitness and strength
OP96S035
NHANES topics
•
•
•
•
•
•
•
Nutrition
Anthropometry
Mental health
Risk behaviors
Reproductive health
Environmental exposures
Infectious diseases
OP96S036
NHANES nutrition assessments
•
Dietary nutrient intake
•
Anthropometric measurements
•
Nutritional biochemistries and
hematologic tests
•
Physical examination
•
Interview
OP96S060
NHANES 1999-2001 Dietary
Assessment
•
•
•
•
•
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24-hour dietary recall (automated )
Second day recall on subset of persons
Food frequency (focused)
General questions
Supplements/medications (detailed)
Food security
NHANES 2002 Dietary Assessment
• 24-hour dietary recall (new USDA
automated system)
• Second day recall on ALL persons
(telephone)
•
•
•
•
Food frequency (focused)
General questions
Supplements/medications (detailed)
Food security
MEC laboratory
• CBC and differential
• Pregnancy test
• Blood, urine and vaginal swab
processing
• 76 different vials of samples
• 26 laboratories
• 300 laboratory assays
Environmental exposure measures
•
•
•
•
•
•
•
•
Lead
Cadmium
Mercury
Pesticides
Selenium
Cotinine
Urinary Iodine
Volatile organic compounds
National Report on Human
Exposure to Environmental
Chemicals
First report - 27 environmental chemicals
including:
• Metals
• Cotinine
• Organophosphate pesticide metabolites
• Phthalate metabolites
Updated annually
Dietary data for future NHANES
•
Continue collection of two recalls on all
sample persons
•
Pilot test in 2002 of a longer food
frequency questionnaire
•
•
Monitor respondent burden
Balance competing needs --- usual
intake, total intake (nutrients vs. foods),
food safety, supplement use, DHKS, food
programs and health components
NHANES web site
http://www.cdc.gov/nchs/nhanes.htm
OP96S058
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