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University of Puerto Rico Río Piedras Campus College of Natural Sciences Nutrition and Dietetics Program Program: Bachelor of Science in Nutrition and Dietetics Human Biochemistry, NUTR 4158 First Semester, 2013-2014 Academic Year Sec. 0U1, Monday, 1:00 p.m. – 3:50 p.m. Room NEP 576 Michelle Schelske Santos, Ph.D.; [email protected], [email protected]; ext. 5798, 2792 Date Assignment Topic 12Aug13 Syllabus; Reflection Reserve: Harper’s Illustrated Biochemistry Ch. 1 Sign up for course in Edu 2.0 Quiz – Cells and Organelles Chapters 1, 2; bring calculators Reserve: Harper’s Illustrated Biochemistry Ch. 2 Chapter 2; bring calculators Chapter 8; Web Tutorial – Nucleotides & nucleic acids Assignment - pH problems in Edu 2.0 Chapters 24, 9 (pp. 306-9, 317, 319-25, 333-8); Animations: Ch. 24 Packaging of Nuclear Chromos; Ch. 9 DNA Cloning, PCR Nutrigenomics and Nutrigenetics Chapters 3 (pp. 75-106; no section 3.3 nor 3.5) Due: pH problems Assignment – ELSI of Human Genome Project Academic Recess – Labor Day Quiz – Amino acids Chapter 4 (eliminar pp.126-137); Web Lehninger 3D Tutorial; Protein Architec. Chapter 5, part I; (sections from Chapters 21, 23, 28) Due: ELSI of Human Genome Project & Topic Oral Presentation Assign: Search Strategy, & prelimin. results for Oral Presentation LAB (substitute for Oral Presentations on W, 13Nov13) Introduction to course Biochemistry in Health Sciences The cells and organelles The cells and organelles (cont.); Overview of structure and characteristics of biomolecules; Water pH, acid/base balance, buffer systems Nucleotides & nucleic acids OPPORTUNITY 1: Cells/water – Nutrigenomics (Ch. 1, 2, 8, 24, 9, 3, 4) 19Aug13 26Aug13 W, 28Aug13 rep., 02Sep13 02Sep13 09Sep13 W, 11Sep13 rep. 25Nov13 Fri, 13Sep13 TBA 16Sep13 23Sep13 DNA & RNA structure and metab.; DNA techniques; The Human Genome Project; Ethical implications of availability and use of genetic info. with applications in nutr. Proteins I: amino acids, peptides Proteins I: amino acids, peptides & proteins; 3D structure of proteins Protein Functions I (Intro., Insulin, Leptin, Lipoproteins) Chapter 5, part II Protein Functions II (Hemoglobin, Due: Search Strategy, & prelimin. results for Oral Immunoglobulins, Actin, Myosin); Presentation Chapter 6; Chapter 27; Enzymes; Protein metabolism; Assign: Continue article search for oral pres. Dra. M. Schelske Santos; NUTR 4158 30Sep13 07Oct13 Chapter 18 part I Due: Articles for Oral Presentation Chapter 18 part II; 22 (sec. 2 - 3) Urea cycle, amino acid oxidation Amino acid metabolism, oxidation, degradation; Amino acid synthesis, molecules derived from amino acids Tue, 08Oct13 OPPORTUNITY 2: Protein Structure, Function & Ch. 5, (sections from 21, 23, 28) 6, ? Metabolism 27, 18, 22 14Oct13 Chapters, 13 (sec. 3 - 4), 16, 19 Bioenergetics; Citric Acid Cycle, Assignment Electron Transport Chain 21Oct13 Quiz: ATP & TCA Cycle Carbohydrate Structure, Carbohydrate Chapters 7, 14, 15 Metabolism I (Glycolysis, and Gluconeogenesis), & II (Glycogenolysis and Glycogenesis) 28Oct13 Chapter 15 (cont.), Carbohydrate Metabolism II (cont.) Chapter 23 Hormonal reg. of sugar metabolism; 04Nov13 Chapter 10, 11, 17 Lipid Structure, Membranes; Lipid If offered, Extra Credit Assign? (optional) Metabolism I Fri, 08Nov13 OPPORTUNITY 3: Protein and Amino Acid Meta- Ch. 13, 16, 19, 7, 14 bolism, Bioenergetics, CHO Structure, Glycolysis 11Nov13 Academic Recess – Veteran’s Day Wed, 13Nov13 Oral presentations of biomolecules under investigation (10 min. each); questions and Subs. 11Sep13 Due: Written reports of presentations discussion 18Nov13 Oral presentations of biomolecules under investigation (10 min. each); questions and Due: Written reports of presentations discussion 25Nov13 Academic Recess – Happy Thanksgiving! 02Dec13 Chapters 21 Lipid Metabolism II Chapter 22 (sec. 4); Nucleotide Metabolism Final Reflection; Review for final Due: Extra Credit (optional) Assignment: Electronic Forum – Edu 2.0 (30 pts.) 11-18Dec13; OPPORTUNITY 4: FINAL (150 pts.; 30 pts. from Part new material (Ch. 15, 23, 10, 11, TBA Electronic Forum, 120 pts. in class) 17, 21, 22) ; Part comprehensive (entire semester) This schedule is subject to change based on unforeseen events, natural disasters, and scheduling of student assemblies. In the event of any change, a new schedule will be developed and available in Edu 2.0. sem. 1, 2013-2014 Page 2 of 2