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Transcript 
ASPIRIN
MELISSA GERSON
GENERAL USES OF ASPIRIN
• Pain Reliever
• Fever Reducer
• Anti- Inflammatory
• Known as: nonsteroidal anti-inflammatory
drug (NSAID)
HISTORY OF ASPIRIN
• 3000 B.C.- 1500 B.C. – Willow is
used by ancient civilizations
• 5th Century B.C. – Hippocrates uses
Willow
HISTORY OF ASPIRIN CONTINUED…
• 1700s- Reverend Edmund Stone wrote
about a similar success
• 1829- Henri Leroux found that Salicin
is the active ingredient found in the
Willow Bark
CREATION OF ASPIRIN
• 1897- Dr. Felix Hoffman discovered the
chemical compound the created Aspirin
• 1899- A chemist working with Hoffman
at Bayer assisted with the research and
promoted the usefulness of the drugnamed it Aspirin
HISTORY CONTINUED
• 1982- John Vane wins Nobel Prize
THE INVENTOR
• Dr. Felix Hoffmann
HOW DOES PAIN WORK?
• Cyclooxygenase-2 creates
prostaglandin (enzyme)
• Prostaglandin tells the brain that an
area is in pain
HOW DOES ASPIRIN RELIEVE PAIN?
• Aspirin – known as a
COX-2 inhibitor works by
latching on to the
enzyme which stops it
from working
HOW IT IMPACTED US
• Uses for a variety of
different health
conditions
• Improves quality of life
INTERESTING FACTS
Taking a low dose of Aspirin may
reduce the risk of heart attacks.
In 1950, Aspirin was
acknowledged as the world’s
highest selling drug by the
Guinness Book of World Records
SOURCES
Aspirin: MedlinePlus Drug Information. (2016, May 24). Retrieved June 02, 2016, from
https://www.nlm.nih.gov/medlineplus/druginfo/meds/a682878.html
Connelly, D. (2014). A history of aspirin. The Pharmaceutical Journal.
Goldberg, D. R. (n.d.). Aspirin: Turn of the Century Miracle Drug | Chemical Heritage Foundation. Retrieved June 02,
2016, from http://www.chemheritage.org/discover/media/magazine/articles/27-2-aspirin.aspx
Ling, G., Ross-Flanigan, N. U., Ross-Flanigan, N., & JENNETT, C. B. (1994, January 01). Aspirin. Retrieved June 02,
2016, from http://www.encyclopedia.com/topic/aspirin.aspx
Park, K., & Bavry, A. A. (2013). Aspirin: Its risks, benefits, and optimal use in preventing cardiovascular events. Cleveland
Clinic Journal of Medicine, 80(5), 318-326.
PICTURES
• http://www.dailymail.co.uk/health/article-3155608/Aspirin-harm-good-heart-patients-Doctors-toldnot-prescribe-drug-life-threatening-condition-causes-heart-beat-fast.html
•
• https://upload.wikimedia.org/wikipedia/commons/6/67/Felix_Hoffman.jpg
•
• https://upload.wikimedia.org/wikipedia/commons/7/7c/Hippocrates.jpg
•
• https://upload.wikimedia.org/wikipedia/commons/a/ab/Salicin-2D-skeletal.png
• https://en.wikipedia.org/wiki/Nobel_Prize
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