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10 m
Human height
Length of some
nerve and
muscle cells
0.1 m
Chicken egg
1 cm
Ribosomes
Frog egg
Most plant and
animal cells
Nucleus
Most bacteria
1 µm
100 nm
10 nm
1 nm
0.1 nm
Outside of cell
Mitochondrion
Smallest bacteria
Viruses
Ribosomes
Proteins
Plasma membrane
Cell wall
Bacterial
chromosome
Electron microscope
100 µm
10 µm
Nucleoid
Light microscope
1 mm
Fimbriae
Unaided eye
1m
Capsule
0.5 µm
Flagella
(a)
A typical
rod-shaped
bacterium
(b)
A thin section
through the
bacterium
Bacillus
coagulans (TEM)
Lipids
Small molecules
Atoms
1
2
Surface area increases while
total volume remains constant
(a)
TEM of a plasma
membrane
5
Inside of
cell
1
0.1 µm
1
Carbohydrate side chain
Total surface area
[Sum of the surface areas
(height × width) of all boxes
sides × number of boxes]
Hydrophilic
region
Total volume
[height × width × length ×
number of boxes]
Hydrophobic
region
Hydrophilic
region
Phospholipid
Surface-to-volume
(S-to-V) ratio
[surface area ÷ volume]
Proteins
6
150
750
1
125
125
6
1.2
6
(b) Structure of the plasma membrane
3
ENDOPLASMIC RETICULUM (ER)
Flagellum
Rough ER
Smooth ER
Nuclear envelope
NUCLEUS
Nucleolus
Chromatin
Nuclear
envelope
Nucleolus
4
NUCLEUS
Chromatin
Rough endoplasmic
reticulum
Smooth endoplasmic
reticulum
Ribosomes
Centrosome
Plasma
membrane
Central vacuole
Golgi
apparatus
CYTOSKELETON:
Microfilaments
Microfilaments
Intermediate
filaments
Microtubules
Intermediate
filaments
Microtubules
CYTOSKELETON
Ribosomes
Mitochondrion
Microvilli
Peroxisome
Golgi
apparatus
Peroxisome
Mitochondrion
Chloroplast
Plasma
membrane
Cell wall
Plasmodesmata
Wall of adjacent cell
Lysosome
5
6
Nucleus
Central vacuole
Rough ER
Cytosol
Smooth ER
cis Golgi
Central
vacuole
Nucleus
Cell wall
Chloroplast
Plasma
membrane
trans Golgi
5 µm
7
8
Intermembrane space
Outer
membrane
Ribosomes
Free
ribosomes
in the
mitochondrial
matrix
Stroma
Inner and outer
membranes
Granum
Inner
membrane
Cristae
Thylakoid
1 µm
Matrix
0.1 µm
9
Direction of swimming
(a) Motion of flagella
5 µm
Direction of organism’s movement
Power stroke
Recovery stroke
(b) Motion of cilia
15 µm
11
10
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