Download Years (April 2000-2002)

Curriculum Vitae (CV)
Personal Details
Full name
Address
Frouzandeh Mahjoubi
NIGEB, P.O Box 14155-6343, Tehran, Iran
Tel. (Work)
9821-44580389
Fax. (work)
9821-44580399
Date of Birth
12, March, 1967
Citizenship
Iranian
Undergraduate studies
Name of the university
Years
Chamran University
1985-1989 (Full-time)
Awarded the B.Sc
Postgraduate studies
Name of the university
Years
The University of Wollongong
March 1993 - September 1994 (Full-time)
Attained the M.SC(honours) in Biotechnology.
The Title of the thesis
Optimisation of Degenerate Oligonucleotide Primed
PCR (DOP-PCR) for the amplification of
microdissected chromosome segments
Name of the university
Years
Macquarie University
July 1995-March 2000
Awarded PhD
The Title of the thesis
Chromosome Microsurgery And Its Applications
Name of the institute
Years
CSIRO
April 2000-January 2002
Postdoctoral fellow
Awards
The MCHE Scholarship (Iran),
The Postgraduate Research Fund (Macquarie University)
The Postgraduate Research Fund (CSIRO)
The Postdoctoral Fellowship Award (CSIRO)
Work Experience
Position
Years
Duties
Medical laboratory scientist (Bograt Medical Laboratory, Iran)
(July 1989-November 1992)
Supervision of technicians, routine blood and urine testing,
urine chromatography, and infertility tests
Position
Years
Duties
Research scientist (CSIRO, Division of Molecular Science)
(April 2000-2002)
Preparation of the chromosome specific paint
from patient’s chromosomes to analyze the
origin of their chromosomal abnormalities using
chromosome microsurgery, PCR and FISH.
Transferring the technology of chromosome
microsurgery to a interested hospital laboratory.
Performance of a range of standard Molecular
Biology techniques such as tissue culture,
Southern Transfers etc.
Position
Years
Duties
Research scientist (NIGEB, Medical Genetic Dept.)
(Oct 2002- continue)
Supervision of the MSc and PhD students, Project
leader
(Project
title:
Investigation
of
gene
amplification in Iranian AML patients), Teaching
Position
Years
Duties
Head of the Medical Genetic Dept. IBTO
(May 2003- continue)
Supervision
of
the
research
scientists
and
technicians
Special skill
Chromosome microsurgery, Specific forms of
PCR, FISH, Preparation of specific FISH probe,
Microarry
Publications
51. Frouzandeh
Mahjoubi*, Greg Peters, Ron Hill, Art Daneil. An analphoid marker
chromosome inv dup(15)(q26.1qter), detected during prenatal diagnosis and characterized via
chromosome microdissection. Cytogenetics and Genome Research (2005) ; Vol. 109, No. 4:
485-490
50. F. Mahjoubi*, S. Totian, S. Kareemy, Y. Shafegatee. Trisomy 8p (p11.2—pter)
due to maternal translocation t(8;13)(p11;p12) in a child with dysmorphic features.
Indian Journal of Human Genetics (2005); Vol 11, No. 2: 111-113
49. F. Mahjoubi*, Greg Peters, Ron Hill. Microdissection of amplified drug-resistance genes,
an approach to understand drug resistance in cancer. Chromosome Research (2006);14(3):26376
48. Tootian.S¹, F. Mahjoubi. *Cytogenetic Investigation in Iranian patients suspected
of Fanconi Anemia. Journal of Pediatric Hematology/Oncology (2006);28(12):834-6.
47. M. Golalipour. F. Mahjoubi, * M Sanati, K. Alimogaddam. Gene dosage is not
responsible for the upregulation of MRP1 gene expression in adult leukemia patients.
Arc Med Res (2007). Apr;38(3):297-304
46. M. Golalipour. F. Mahjoubi*, M Sanati. RNAi induced inhibition of MRP1
expression and reversal of drug resistance in human promyelocytic HL60 cell line.
Iranian Journal of Biotechnology (2007). 38(3):297-304
45. Akbari S, Mahjoubi F*, Monatzeri M, Nazari Sh, Elahi, E. Comparison between
the expression of MRP1 in pediatric leukemic patients with different response to
chemotherapy. J of Genetic Novin (2007) , 2; 67-73
44.B. Shams , F. Mahjoubi* , M. Montazeri, A. Salehi. Production of Bovine Y
chromosome specific FISH probe for validation of cattle sperm separation procedures.
Journal of Genetic Novin, (2007), 4 ;49-54
43. Frouzandeh Mahjoubi*, Masoud Golalipour, Kamran Alimoghaddam. Expression
of MRP1 gene in acute leukemias. Sao Paolo Med J (2008) 126 ; 172-179
42.F. Mahjoubi* , MT Akbary , GH Babamohammadi. Clinical features of a case
with trisomy 10q and monosomy 3p resulting from a maternal balanced translocation: A
case report and review of clinical features. Journal of Pediatric Nourology (2008); 6(3):
273-276).
41.N. Vasly, M. Norouzynia, A. Saremy, M. Azmy, F. Mahjoubi. Investigation of
APC mutations in Iranian FAP patients employing Conformation Sensitive Gel
Electrophoresis. Oloom Pezeshky Modaress (2008): 1-8
40. Frouzandeh Mahjoubi*, Soodeh Akbari, Maryam Montazeree,
Farzaneh
Moshyree. MRP1 polymorphisms (T2684C, C2007T, C2012T and C2665T) are not
associated with multidrug resistance in leukemic patients. Journal of Medical Research
(2008);7(4):1369-74
39. Barzehkar Roohallah, Salehi Abdolreza, Mahjoubi Frouzandeh. Polymorphisms
of the ovine leptin gene and its association with growth and carcass traits in three
Iranian sheep breeds. Iranian Journal of Biotechnology. (2009);7 (12): 241-246
38. Hamid, M, Karimpour M, Mahjoubi F*. Molecular analysis of HS-111 and 3`HS1
variations in β-thalassemia intermedia patients with high levels of HbF. Yakhte (2009)
Vol 44; 418-423
37. Hamid M, Mahjoubi F, Akbari MT, Zeinali S, Karimipoor M. The Cretan type of
nondeletional hereditary persistence of fetal hemoglobin in an Iranian family. Ann
Hematol. (2009);88(12):1267-8.
36. Rezvani S, Montazeri M, Mahjoubi F*. Study of the effect the of MRP1 gene
polymorphisms on its mRNA expression in acute leukemic patients. Journal of
Zystshenasy (2001) Vol (24);1-9
35. M Tahery, F. Mahjoubi*, R Omranipour, F Feraidony. Investigation of MDR1
C3435T polymorphism in Patients with breast cancer. Tabeeb Sharg (2009) Vol 11 ;917
34. Hamid M, Mahjoubi F, Arab A Zeinali S, Akbari MT and Karimipoor M .
Molecular analysis of γ-globin promoters, HS-111 and 3`HS1 in beta thalassemia
intermedia patients associated with high levels of HbF. Hemoglobin( 2009) 33(6):42838
33. Nasiri F, Mahjoubi F*, Babamohammadi G. De novo duplication of chromosome
7(q21.1-q32), case report and review from the literature. BJMG (2010)13: 35-37
32. Taheri M, Mahjoubi F*, Omranipour R. The effect of MDR1 polymorphism on its
expression in Breast Cancer Patients. Journal of Medical Research. Genet Mol Res.
(2010 ) 12;9(1):34-40
31. Mahjoubi F*, Zolfagary N. A Partial trisomy 2p(p21 pter) derived from a paternal
t (2;4)(p21;q33) karyotype. BJMG (2010) 13: 41-44
30. Mahjoubi, *Frouzandeh; Soleimani, Saeideh; Mantegy, SanazChromosomal
Abnormalities in Infertile Men Referred to Iran Blood Transfusion Organization
Research Center. Journal of Reproduction and Infertility (2010) 11:775-779
29. Frouzandeh Mahjoubi , Mona Malek Mohammadi, maryam Montazeri, Massod
Amini, and Mahin Hashemipour. Mutations in the gene encoding paired box domain
(Pax8) are not a frequent cause of congenital hypothyroidism (CH) in Iranian patients
with thyroid dysgenesis. Arq Bras Endocrinol Metabol( 2010) 54(6):555-9
28. Hamid M, Mahjoubi F, , Akbari MT, Khan Ahmad H, Jamshidy F, Zeinali S and
Karimipoor M. Transient Expression Assay of g-588 (A/G) mutation in the K562 cell
line. Iranian Biomedical Journal ( 2011);15(1-2):15-21.
27. F.Mahjoubi, F. Nasiri,R.Torabi. Partial trisomy 9p(p22:pter) from a maternal
translocation 4q35 and 9p22. BJMG (2011);14:61-66
26. Zahra Lashgary, Ahmad Khodadadi, Yoginder Singh,Seyed Massoud Houshmand,
Frouzandeh Mahjoubi, Prithviraj Sharma, Shweta Singh, Mahtab Seyedin , Amit
Srivastava, Mirtra Ataee, Zeinab Sadat Mohammadi, Nima Rezaei, Rameshwar N.K.
Bamezai, Mohammad Hossein Sanati. Y chromosome diversity among the Iranian
religious groups: a reservoir of genetic variation. Annals of Human Biology (
(2011);38(3):364-71
25. Mahjoubi F, Akbary MT, Shafegatee Y. XYY Karyotype in a mentally retarded
man with prognathism and malformation of his hands and toe nails. BJMG (2010). 14:
20-24
24. Arash Akbarzadeh, Hamid Farahmand, Frouzandeh Mahjoubi, Mohammad Ali
Nematollahi, Piia Leskinen, Kalle Rytkönen, Mikko Nikinmaa. The transcription of Lgulono-gamma-lactone oxidase, a key enzyme for biosynthesis of ascorbate, during
development
of
Persian
sturgeon
Acipenser
persicus
(2010).
Comparative
Biochemistry and Physiology - Part B. Comp Biochem Physiol B Biochem Mol Biol.
(2011);158(4):282-8.
23. Frouzandeh Mahjoubi, Shahriar Nafissi , Maryam Montazeri, Shohre Zare-karizi.
Employing Real Time PCR for the Diagnosis of Huntington disease. Zahedan Journal
of Medical Research,(2012) 15(7): 26-30
22. F Mahjoubi , F Razazian. Constitutional complex chromosomal rearrangements in
a klinefelter patient: case report and review of literature. Journal of Assisted
Reproduction and Genetics(2012)29:437-441
21. Sara Samanian, Frouzandeh Mahjoubi*, Bahar Mahjoubi, Rezvan Mirzaee,
Rasool Azizi. MDR1 Gene Polymorphisms: Possible Association with its Expression
and Clinicopathology Characteristics in Colorectal Cancer Patients. Asian Pacific J
Cancer Prev,(2012) 12, 3153-3157
20. Sara Samanian, Bahar Mahjoubi, Frouzandeh Mahjoubi*, Rezvan Mirzaee,
Rasool Azizi. Association between MDR1 and MRP1 expression levels and
clinicopathology markers in colorectal patients. Zahedan Journal of Medical
Research,(2012) 15 (7):31-34
19. F. Mahjoubi, F. Nasiri, F, Razazian. Concurrence of inv (7)(q11.2q32), and
del(8)(p23.1) in a girl with congenital microcephaly, hypotonia, developmental delay,
strabismus, hypernatremia, hypermagnesemia and deafness. Journal of Genetic
Counseling. (2012 ) 23(3):397-404
18. S. Samanian, F. Mahjoubi. Genotype and allele frequencies of MDR1 gene
C3435T and C1236T polymorphisms in an Iranian population. Journal of Genetic
Novin (2012) 3:221-226
17. Frouzande Mahjoubi, Mahin Hashemipour, Ramin Iranpour, Massoud Amini,
Silva Hovsepian. TTF2 Gene Mutation in Neonates with Congenital Hypothyroidism
Caused by Thyroid Dysgenesis. Journal of Isfahan Medical School. (2012) 30, 1-11
16. Mahjoubi F, Akbari S. Multidrug resistance-associated protein 1 predicts relapse
in Iranian childhood acute lymphoblastic leukemia.Asian Pac J Cancer Prev.
(2012);13(5):2285-9
15. F. Nasiri , F. Mahjoubi, F. Manouchehry , F.Razazian , F.Mortezapour ,
M.Rahnama . Cytogenetic Findings in Mentally Retarded Iranian Patients. BJMG
(2012); 15(2):29-35
14. F. Izadi, F.Mahjoubi, M. Farhadi,, M. Moein Tavakoli, S. Samanian. A novel
missense mutation in exon 7 of the ECM1 gene in an Iranian lipoid proteinosis patient.
GMR (2012); 4:3955-3960
13. F.Mahjoubi, ,M.Rahnama, R. Torabi, Partial trisomy 13q in a blind and deaf baby
boy. Journal of Genetic Counseling (2013) 24( 1) : 93-94
12. Mahjoubi F, Hashemipour M, Moshiri F, Iranpour R, Amini M, Hovsepian S, et
al. Genetic analysis of TTF2 gene in congenital hypothyroid infants with thyroid
dysgenesis. Pak J Med Sci (2013);29(1)
11. Mohsen Taheri, Frouzandeh Mahjoubi.MRP1 but not MDR1 is associated with
response to neoadjuvant chemotherapy in breast cancer patients. Journal of Disease
Marker (2013) 34 : 387–393
10. M Mirakhorli, Sabariah Abdulrahman * Syahrilnizam Abdullah, Masoud Vakili,
Ahad Khoshzaban, Frouzandeh Mahjoubi. Multidrug resistance protein genetic
polymorphism colorectal cancer recurrence in patients receiving adjuvant FOLFOX-4
chemotherapy. Molecular Medicine Reports (2013) 7: 613-617
9. Ramyar Molania, Frouzandeh Mahjoubi*,Rezvan Mirzaei, Saeed-Reza khatami,
Bahar Mahjoubi. A panel of cancer testis antigens (CTA) and clinical risk factors to
predict metastasis in colorectal cancer. Journal of Biomarkers (2014) 1 : 1-8
8. F Mahjoubi , F Razazian , R Torabi. A case with 46,XX,del(11)(q23.2) karytype
and poor vision with literature review. Journal of Genetic Counseling (2014) 2:277-287
7. MR Nowruzfashkhami, LAzizzadeh pormehr, F Mahjoubi, M Pourkazemi, B
Kazemi, S Hassanzadeh, M Yarmohhamadi. Isolation of HindIII SatDNA in Persian
sturgeon Acipenser persicus (2013) 1 :121-126
6. N Mokhberian N, F Mahjoubi, R Pourahmad . Investigation of G2677T/A
polymorphism in MDR1 gene of childhood acute lymphoblastic leukemia Sci J Iran
Blood Transfus Organ (2014) 11(2): 103-109
5. Samira Shabani, Frouzandeh Mahjoubi, Bahar Mahjoubi, Rezvan Mirzaee.
Investigation of hTERT expression level and its relation with clinicopathological
features and resistance to chemotherapy in colorectal cancer patients. Journal of
Pharmaceutical Sciences (2014)
4. Samira shabani, Sara Samanian, Rezvan Mirzaei, Bahar Mahjoubi, Frouzandeh
Mahjoubi. Correlation among MDR1, MRP and hTERT Genes Expression Level and
Clinical Response in Colorectal Cancer Patients. J Mol Biomark Diagn 2014, 3-:5
3. Ali Akbar Saffar Moghadam, Frouzandeh Mahjoubi, Nahid Reisi, and Parvaneh
Vosough Investigation of FANCA gene in Iranian Fanconi Anemia Patients . Indian
Journal of Medical Research (2014). Accepted
2. Elham Arbabi Aval, Frouzandeh Mahjoubi, Raheleh Torabi. Single Cell PCR
Using Y Chromosome Specific Repeat for Sexing. Journal of Advances in Biology &
Biotechnology (2015), 2(1): 59-64
1.Farzad Izadi, Frouzandeh Mahjoubi, Mohammad Farhadi, Samira Kalayi nia 3, Ali
Bidmeshkipour, Mohammad. Moein Tavakoli, Sara Samanian. Extracellular Matrix
Protein 1 Gene (ECM1) Mutations in 9 Iranian families with Lipoid Proteinosis. Indian
Journal of Medical Research (2015). Accepted
Membership:
Auatralian Society of Human Genetics
Australian Society of Cytogenetics
Asutralian Society of Medical Research
Iranian Society of Human Genetics
Board Memeber:
Member of the Board of the Iranian Society of Genetics
Member of the Board of the Iranian Society of Human Genetics
Member of the Board of the Genetic Foundation of Tehran