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Pharmaceutical and Pharmacological Sciences 1 Pharmaceutical and Pharmacological Sciences Degree Offered • Doctor of Philosophy Introduction The WVU School of Pharmacy offers graduate programs in the pharmaceutical and pharmacological sciences for the Ph.D. degree. The school is advantageously located in the Health Sciences Center complex which also houses all departments of the Schools of Medicine, Nursing, and Dentistry, as well as a comprehensive medical library, audio-visual and computer-based learning center, research core facilities, and laboratory animal quarters. State-of-the-art research laboratories are located throughout the Health Sciences Center complex to facilitate interactions with the Mary Babb Randolph Cancer Center, Center for Neuroscience, and Center for Cardiovascular and Respiratory Sciences. In addition, the Health Sciences Center has easy access to the Evansdale and Downtown campuses of WVU through a personal rapid transit (PRT) system. The scientific community, which is especially well-developed, draws on area scientists throughout WVU, the Centers of Disease Control/National Institute on Occupational Safety and Health (CDC/NIOSH), Federal Bureau of Investigation (FBI), and a variety of research centers supported by the National Institutes of Health (NIH), National Science Foundation (NSF), and the Department of Energy (DOE). A CDC/NIOSH research facility is two blocks away, and Mylan Pharmaceuticals, a leading generic drug producer in the world, is located across the street from the Health Sciences Center. In addition, the school has long-standing collaborations with several state agencies and multinational pharmaceutical companies. Degree Offered • Doctor of Philosophy Research interests are complementary to the focus of pharmaceutical and pharmacological sciences. Key areas of research interest and expertise in pharmaceutical and pharmacological sciences include: pharmaceutical sciences, pharmacology, cancer, neuroscience, nanoscience, and toxicology. Graduate Program Pharmaceutical and Pharmacological Sciences The School of Pharmacy offers a doctor of philosophy (Ph.D.) degree in pharmaceutical and pharmacological sciences. The graduate program provides interdisciplinary, research-oriented curricula designed to develop the interests, capabilities, and potential of the individual student. Specialty areas of study include: pharmacology, drug metabolism, cancer cell biology, nanotechnology. Upon completion of the second year of study, students must submit a formal plan of study and a research plan that is approved by their Ph.D. committee. Progress is expected to continue with guidance from the student’s research committee. Final admission to candidacy requires satisfactory performance on written and oral qualifying examinations as well as a dissertation proposal defense. Subsequent to admission to candidacy, a substantial part of the program is devoted to an original research project which culminates in a first-authored publication and dissertation. To be recommended for a Ph.D., the dissertation must be satisfactorily completed and defended at an oral examination. Academic Standards No credits are acceptable toward a graduate degree with a grade lower than a C. A graduate student is expected to have a cumulative grade point average of at least 3.0 in all graduate courses to continue in the program and to qualify for a Ph.D. degree. Admission Requirements Applicants for admission into the graduate program must satisfy the WVU and Health Sciences Center general requirements for admission as a graduate student. The applicant must possess a baccalaureate degree, background in a suitable area of study, an overall grade point average of at least 3.0, and the aptitude and interest for graduate work in pharmaceutical and pharmacological sciences or health outcomes research to be admitted. Graduate Record Examination (GRE) scores in the verbal, quantitative, and analytic essay portions are required from all students planning on entering the graduate program. TOEFL scores are required of international students from countries where English is not the primary language. To obtain specific information related to the school’s graduate programs, graduate faculty research interests, and availability of graduate assistantships or fellowships, applicants may contact: Office of Research and Graduate Programs WVU School of Pharmacy 2037 Health Sciences Center North P.O. Box 9530 Morgantown, WV 26506 Telephone: (304) 293-0944 e-mail: [email protected] 2 Pharmaceutical and Pharmacological Sciences Doctor of Philosophy The School of Pharmacy offers a doctor of philosophy (Ph.D.) degree in pharmaceutical and pharmacological sciences with two pathways aimed at training competent researchers and educators: pharmaceutical and pharmacological sciences, and health outcomes research. MAJOR REQUIREMENTS Pharmaceutical & Pharmacological Sciences Pathway 84-120 BMS 700 Scientific Integrity 1 BMS 706 Cellular Methods 1 BMS 715 Molecular Genetics 3 BMS 720 Scientific Writing BMS 797 Research 1-5 BMS Course Fundamentals of Contemporary Biomedical Research 1-8 Graduate Seminar PHAR 796 6 Graduate Seminar Research PHAR 797 PHAR 798 2 40-50 Research Thesis or Dissertation Journal Clubs (Select from the following) PHAR 783 Pharmacy Cell Biology Seminar PHAR 784 Pharmacology Journal Club PHAR 787 Drug Discovery and Development Advanced Courses/Electives 6 6 14-21 BIOC 791 Advanced Topics CHEM 335 Methods of Structure Determination CHEM 346 Physical Chemistry CHEM 514 Mass Spectrometry Principles and Practices CHEM 531 Advanced Organic Chemistry 1 CHEM 531 Advanced Organic Chemistry 1 PCOL 743 Pharmacology 1 PCOL 744 Pharmacology 2 PCOL 745 Advanced Pharmacology 1 PCOL 746 Advanced Pharmacology 2 PHAR 711 Chemical Properties of Drugs PHAR 716 Chemistry of Drug Action 1 PHAR 726 Chemistry of Drug Action 2 PHAR 731 Pharmacogenomics and Pharmacokinetics PHAR 779 Drugs: Bench to Market PHAR 780 Introduction to Molecular Modeling PHAR 781 Drug Metabolism Laboratory Rotations 1 1-3 Laboratory Rotations 2 1 Laboratory Rotations 3 1 Qualifying Exams Dissertation Proposal Defense Dissertation Defense Total Hours for Pharmaceutical & Pharmacological Sciences Pathway Health Outcomes Research Pathway 84-120 73 BIOS 601 Applied Biostatistics 1 3 BIOS 602 Applied Biostatistics Lab 1 BIOS 603 Applied Biostatistics 2 3 BIOS 604 Applied Biostatistics 3 3 Pharmaceutical and Pharmacological Sciences 3 BMS 720 Scientific Writing 2 PHAR 753 Social and Behavioral Theory and Health Outcomes Research 3 PHAR 755 Pharmacoeconomics 3 PHAR 756 Health Survey Research Methods 3 PHAR 757 Patient Reported Outcomes 3 PHAR 758 Ethical and Regulatory Aspects of Clinical Research 1 PHAR 785 Pharmacoepidemiology 3 PHAR 786 Health Services Research and Secondary Database 3 Graduate Seminar (taken each semester) PHAR 788 PHAR 797 12 Graduate Seminar in Health Outcomes Research (Repeated) Research 1-15 Electives 12 Dissertation PHAR 798 8 Thesis or Dissertation Qualifying Exams Dissertation Proposal Defense Dissertation Defense Total Hours for Health Outcomes Research Pathway 76-90 PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES PATHWAY SUGGESTED PLAN OF STUDY First Year Fall Hours Spring Hours Summer Hours BMS 700 1 BMS 715 3 BMS 720 2 BMS 706 1 Laboratory Rotations 2 1 PHAR 797 2 Laboratory Rotations 1 1-3 Laboratory Rotations 3 1 BMS Course Fundamentals of Contemprary Biomedical Research 1-8 Advanced Courses/ Elective Modules (selected from the list) 5-9 BMS 797 1-5 *Students must sign up for a minimum of 9 hours 5-18 10-14 4 Second Year Fall Advanced Courses/ Elective Modules (Select from the list) Hours Spring 3-6 Advanced Courses/ Elective Modules (select from list) Hours Summer 3 PHAR 797 PHAR 796 1 PHAR 796 1 Journal Club (Select from the following) 1 Journal Club (Select from the following) 1 PHAR 783 PHAR 783 PHAR 784 PHAR 784 PHAR 787 PHAR 787 PHAR 797 4-5 PHAR 797 Hours 6 4-7 Take Qualifying Exams 9-13 9-12 6 Third Year Fall Advanced Courses/ Elective Modules (Select from list) Hours Spring 3 PHAR 798 Hours Summer 2-4 PHAR 797 Hours 6 4 Pharmaceutical and Pharmacological Sciences PHAR 796 1 PHAR 796 1 Journal Club (Select from the following) 1 Journal Club (Select from the following) 1 PHAR 783 PHAR 783 PHAR 784 PHAR 784 PHAR 787 PHAR 787 PHAR 797 3-4 PHAR 797 Proposal Defense 3 *Students must sign up for a minimum of 9 hours *Students must sign up for a minimum of 9 hours 8-9 7-9 6 Fourth Year Fall Hours Spring Hours Summer PHAR 797 3-6 PHAR 797 3-5 PHAR 797 PHAR 798 2-4 PHAR 798 2-4 PHAR 796 1 PHAR 796 1 Journal Club (Select from the following) 1 Journal Club (Select from the following) 1 PHAR 783 PHAR 783 PHAR 784 PHAR 784 PHAR 787 Hours 6 PHAR 787 *Students must sign up for a minimum of 9 hours 7-12 7-11 6 Total credit hours: 84-120 HEALTH OUTCOMES RESEARCH PATHWAY SUGGESTED PLAN OF STUDY First Year Fall Hours Spring Hours Summer Hours BIOS 601 3 BIOS 603 3 BMS 720 2 BIOS 602 1 Select one of the following: 3 PHAR 798 3 Select one of the following: 2 PHAR 797 1-15 BMS 700 PHAR 754 PHAR 786 PHAR 758 PHAR 788 PHAR 788 1 Electives Select one of the following: 3 Electives 5 1 6 PHAR 755 Select one of the following: 3 PHAR 753 PHAR 756 13 13 Second Year Fall Hours Spring Select one of the following: 3 Select one of the following: PHAR 755 BIOS 604 Hours 3 11-25 Pharmaceutical and Pharmacological Sciences PHAR 785 Select one of the following: 5 PSYC 612 3 SBHS 701 3 PHAR 753 PHAR 788 1 PHAR 756 PHAR 757 3 PHAR 756 3 Select one of the following: PHAR 769 3 PHAR 754 PHAR 788 1 PHAR 786 Select one of the following: 3 Electives PUBA 670 PHAR 798 3 2 2 PHAR 758 PHAR 756 16 17 Total credit hours: 70-84 DOCTOR OF PHILOSOPHY (PHD) Student Learning Outcomes of the Pharmaceutical & Pharmacological Sciences graduate education program are focused on preparing students to become independent researchers. To be successful in our program pathways, students will need to develop competencies in the scientific research process through didactic studies in an area of emphasis and then conceptualizing, designing, conducting, and reporting original research. Student Learning Outcomes • Learn basic and applied principles in specific disciplines and related fields in order to develop a broad background of knowledge. • Develop research skills including scientific communication and critical thinking/problem solving ability by participating in seminars and designated research skill courses. • Gain hands-on experience in conducting original research, including acquisition of background information (e.g. literature research), experimental design and experimentation. • Develop research communication skills by writing abstracts for research presentations, manuscripts for publication, research grant proposals, and a thesis or dissertation. • Gain additional insight into research and scholarship by participating in scholarly exchanges with faculty and students in the WVU School of Pharmacy, the Health Sciences Center (HSC), and the West Virginia University community. • Be able to pursue independent research in specialized fields in interdisciplinary teams and to function and contribute as members of research teams • Be competent scientists that are able to contribute to health-related research, industrial research and development, pharmaceutical education, and scholarship