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CURRICULUM VITAE
Name:
Richard Tuli, M.D., Ph.D.
Business Data:
Address:
Telephone:
CSMC Department of Radiation Oncology, 8700 Beverly Blvd., AC 1022
Los Angeles, CA 90048
(310) 423-4205
Education and Training:
1993-1998
1999-2006
1999-2006
2001-2003
2006-2007
2007-2010
2010-2011
B.S. with Honors, University of Maryland, College Park, MD
M.D., Jefferson Medical College of Thomas Jefferson University, Philadelphia,
PA
Ph.D., Cell and Molecular Biology, College of Graduate Studies of Thomas
Jefferson University, Philadelphia, PA
Pre-Doctoral Fellow, NIAMS-National Institutes of Health, Bethesda, MD
Internship, Internal Medicine, Abington Memorial Hospital, Abington, PA
Resident, Department of Radiation Oncology & Molecular Radiation Sciences,
Johns Hopkins University School of Medicine, Baltimore, MD
Chief Resident, Department of Radiation Oncology & Molecular Radiation
Sciences, Johns Hopkins University School of Medicine, Baltimore, MD
Licensure:
California, Physician & Surgeons Medical License, Exp. 10/31/2016
Board Certification:
Radiation Oncology, Physics & Radiobiology, 2010
Radiation Oncology, Written Clinical, 2011
Radiation Oncology, Oral Clinical, 2012
Professional Experience:
Current Appointment
Associate Professor, Radiation Oncology
Associate Professor, Biomedical Sciences
Core Member, Samuel Oschin Comprehensive Cancer Institute
Staff Physician II, Cedars-Sinai Medical Center
Co-Director, Pancreas Oncology Program, Samuel Oschin Comprehensive Cancer Institute
Service Responsibilities
2011- Attending Physician, Gastrointestinal Radiation Oncology
Departmental/Administrative Appointments
2011-6 Assistant Professor, Radiation Oncology, CSMC
2011-6 Assistant Professor, Biomedical Sciences, CSMC
2011-4 Staff Physician I, Cedars-Sinai Medical Center
2011- Section lead, Gastrointestinal Malignancies, Dept. of Radiation Oncology, CSMC
2015- Staff Physician II, CSMC
2011- Core Member, Samuel Oschin Comprehensive Cancer Institute, CSMC
2011- Member/Dept. Research Coordinator, Interdepartmental Translational Research
Committee, CSMC
2011- Member, Phase 1 Experimental Therapeutics Research Committee, CSMC
2012- Stereotactic Radiotherapy Clinical Lead, Dept. of Radiation Oncology, CSMC
2013- GI Oncology Disease Research Group, SOCCI, Co-Lead
2014- Radiation and Cancer Biology Course Director
2014- Chair, Clinical Competency Committee, Radiation Oncology Residency Program
2016- Associate Professor, Radiation Oncology, CSMC
2016- Associate Professor, Biomedical Sciences, CSMC
2016- Chair, Residency Program Evaluation Committee, Radiation Oncology, CSMC
Professional Activities:
Editorial Boards
Frontiers in Oncology, Radiation Oncology Editor
Journal of Gastrointestinal Oncology – Guest Editor
JAMA Oncology - Reviewer
International Journal of Radiation, Biology, Physics –Reviewer
Practical Radiation Oncology –Reviewer
Gastroenterology – Reviewer
Translational Oncology – Reviewer
Oncotarget - Reviewer
American Journal of Clinical Oncology – Reviewer
HPB - Ad Hoc Reviewer
Committee Service
2013-2015
New Investigator Representative, Gastrointestinal Cancer Committee, RTOG
2013-2014
Cedars-Sinai Medical Staff Leadership Development Program
2014Clinical Algorithms Development, SOCCI-GI Oncology, co-lead
2014Member, Gastrointestinal Cancer Committee, SWOG
2015Planning Committee, GI Malignancies, Los Angeles Radiological Society
2015Protocol Review and Monitoring Committee (PRMC), Voting member
2016-2019
Member, NRG Oncology, General GI Committee
2016-2019
Member, NRG Oncology, Colorectal Cancer Core Committee
2016-2019
Member, NRG Oncology, Non CRC Core Committee
2016-2018
Member, Cancer Committee, Cedars-Sinai Medical Center
2016Continuing Education Committee, Los Angeles Radiological Society
2016-2018
Task Force Member, Guidelines on Radiotherapy for Pancreatic Cancer, ASTRO
Professional Societies
SWOG
NRG - RTOG
American Association for Cancer Research
American Society of Clinical Oncology
American Society for Radiation Oncology
American Brachytherapy Society
Radiological Society of North America
Honors and Special Awards:
1995
1996-1998
2000
2000-2003
2001
2003
2003
2003
2003
2004
2006
2006
2010
2010
2011
2011
University Honors Citation, University of Maryland College Park
Outstanding Academic Achievement Award, University of Maryland College Park
Translational Medical Student Research Program Fellowship, Jefferson Medical
College
Measey Foundation M.D., Ph.D. Student Fellowship
Award of Recognition, Sigma Xi Scientific Research Society, Thomas Jefferson
University Chapter
Thomas Jefferson University Alumni Travel Fellowship
th
Clinical Science Poster Session Winner, 8 Annual American Medical Student
Association
William Potter Student Research Prize, Thomas Jefferson University
Orthopaedic Research and Education Foundation - Medical Student Orthopaedic
Research Fellowship Funded by Pfizer
th
New Investigator Research Award Finalist, 50 Annual Meeting of the
Orthopaedic Research Society
Clinical Clerkship Honors ten times, Jefferson Medical College
The Hyman Menduke Research Prize, Thomas Jefferson University
AACR Scholar-in-Training Award Finalist, AACR Annual Meeting
AACR/ASCO Methods in Clinical Cancer Research Workshop – Vail, CO
ASCO Cancer Foundation Merit Award
AACR Scholar-in-Training Award Finalist, AACR Annual Meeting
Research Grants and Fellowships Received:
Funded/Supported – Active
Phase One Foundation
June 2014-Dec 2016
$324,000
A Phase I study of veliparib (ABT-888) in combination with gemcitabine and intensity modulated
radiation therapy in patients with locally advanced, unresectable pancreatic cancer
PI: Richard Tuli, MD, PhD; 5%
Halozyme
June 2015-June 2016
$188,905
Hyaluronan as a predictive and prognostic marker for pancreatic ductal adenocarcinoma & lung
cancer
Co-I: Richard Tuli, MD, PhD
Merck
Dec 2014-Nov 2015
$75,000
Quantitating the Expression of PD-L1 in Resected Gastric and Gastroesophageal
Adenocarcinoma
PI: Richard Tuli, MD, PhD
UCLA CTSI
Apr 2015-Dec 2015
$10,000
Multi-parametric MRI guided liver stereotactic body radiotherapy
Co-I: Richard Tuli, MD, PhD
Halozyme
Jan 2016-Dec 2016
$83,459
Quantifying glycosaminoglycan content in metastatic pancreatic cancer to liver
Co-I: Richard Tuli, MD, PhD
PANCAN
Oct 2016-Sep 2019
Precision Promise Clinical Trial Consortium
PI: Richard Tuli, MD, PhD
$115,000
CSMC Precision Health Init.
Dec 2016-Nov2018
$100,000
Application of novel high-throughput microculture technology to identify functional microbiome
predictors of patient response to chemoradiation therapy
PI: Richard Tuli, MD, PhD
Pending
Astra Zeneca
June 2016-Dec 2018
$150,000
Phase 1 expansion study of stereotactic ablative body radiotherapy in combination with
Durvalumab PD-L1 inhibtion in locally advanced pancreatic cancer.
NIH U01 1UO1DK108314
Dec 2015-Nov 2020
$2,214,278
Pathophysiology, epidemiology and prevention of pancreatogenic diabetes
Co-I: Richard Tuli, MD, PhD
Completed
R03 CA173273-02
Jul 2012-Jun 2014
$157,724
Deformable registration and adaptive treatment planning for stereotactic body radiation treatment
of pancreatic cancer
Co-I: Richard Tuli, MD, PhD; 3.3%
Unfunded
Abbott Labs
Jan 2013-Dec 2015
Drug supported study
A Phase I study of veliparib (ABT-888) in combination with gemcitabine and intensity modulated
radiation therapy in patients with locally advanced, unresectable pancreatic cancer
Role: Principal Investigator
Status: Active
Halozyme
June 2014
HALO-109-202: A Phase II, Randomized, Study of PEGPH20 with nab-Paclitaxel plus
Gemcitabine compared with nab-Paclitaxel plus Gemcitabine, Stage IV Previously Untreated
Pancreatic Cancer
Role: Co-Investigator
Status: Active
Clovis
June 2014
CO-338-023: Phase 2, Open-Label, Study of Rucaparib for Patients with Pancreatic Cancer and
BRCA Mutation
Role: Co-Investigator
Status: Pending activation
New Link Genetics
August 2014
NLG0505: New Link Genetics study of chemotherapy for patients with borderline resectable or
locally advanced unresectable pancreatic cancer
Role: Co-Investigator
Status: Active
New Link Genetics
January 2013
NLG0405: New Link Genetics HyperAcute®-Pancreatic Cancer Vaccine in Subjects with
Surgically Resected Pancreatic Cancer
Role: Co-Investigator
Status: Completed
Investigator Iniitated Study
March 2015
IIT_PanCax:Treatment for Pancreatic Cancer Cachexia
Role: Co-Principal Investigator
Status: Pending activation
Investigator Initiated Study
July 2013
IIT_PancreasMRI: Improving Pancreas Radiotherapy Plans using Respiration-driven Anatomic
Deformation: A pilot study
Role: Co-Investigator
Status: Completed
Immunomedics
March 2015
IMMU-107-04: Double-Blind, Randomized, Phase III, 90Y-Clivatuzumab Tetraxetan plus LowDose Gemcitabine vs Placebo plus Low-Dose Gemcitabine in Patients with Metastatic (Stage IV)
Pancreatic Adenocarcinoma, Received at Least Two Prior Treatments
Role: Co-Investigator
Status: Pending activation
SWOG
March 2015
S1310: Trametinib or Combination Chemotherapy in Treating Patients With Refractory or
Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery
Role: Co-Investigator
Status: Active
RTOG
August 2014
RTOG 1010: Phase III trial evaluating addition of trastuzumab to trimodality treatment of HER2overexpressing esophageal adenocarcinoma
Role: Principal Investigator
Status: Active
RTOG
March 2015
RTOG 0848: A Phase II-R and a Phase III Trial Evaluating Both *Erlotinib (PH II-R) and
Chemoradiation (PH III) as Adjuvant Treatment For Patients With Resected Head of Pancreas
Adenocarcinoma
Role: Co-Investigator
Status: Active
RTOG
June 2014
RTOG 0631: Phase II/III study of image-guided radiosurgery for localized spine metastases
Role: Co-Investigator
Status: Active
Pending
Investigator Initiated Study
July 2015
High risk pancreatic cancer screening program
Role: Co-Investigator
Status: Pending IRB submission
Investigator Initiated Study
July 2015
ECOG and activity tracker in cancer patients
Role: Co-Investigator
Status: Pending IRB submission
Investigator Initiated Study
July 2015
Multi-parametric MRI Guided Liver Stereotactic Body Radiation Therapy
Role: Co-Investigator
Status: Pending IRB submission
Submitted
R01
February 2016
$750,000
Phase 1 Image-Guided Dose-Escalation of SBRT for Localized Pancreatic Cancer
Role: Principal Investigator
Status: Scored, pending resubmission
Teaching Activities:
Teaching (Lectures)
2010 Multidisciplinary Management of Onc Patients, Johns Hopkins Medical Students
2010 Introduction to Radiation Oncology, Johns Hopkins Medical Students
2011 Introduction to Stereotactic Radiotherapy, Cedars-Sinai Radiation Therapy
2012 Oncologic Emergencies for the Radiation Onc, Cedars-Sinai Medicine Residents
2012 Pancreatic Cancer – Tumor Board, SOCCI, Cedars-Sinai Medical Center
2013 Medical Oncology Fellow Journal Club, Cedars-Sinai Medical Center
2013 Rectal Cancer – Tumor Board, SOCCI, Cedars-Sinai Medical Center
2014 Radiobiology Basics, CSMC Rad Onc and Physics Residents
2014 Linear Energy Transfer and Oxygen Effect, CSMC Rad Onc and Physics Residents
2015 Oncologic Emergencies for the Radiation Oncologist, CSMC Rad Onc Residents
2015 Radiosensitizers and Radioprotectors, CSMC Rad Onc and Physics Residents
2015 UCLA-ACRO Resident Education Symposium, GI Oncology Case Examiner
2016 Research Interns Knowledge Nosh, Research Interns Program, CSMC
2016 Clinical & Translational Research Workshop: Clinical Protocol Development, Lecturer and
protocol mentor, CSMC
st
2016 Co-Director, 1 Annual Pancreatic Cancer Conference CME, Cedars-Sinai
Research Mentoring (Pre- and Post-Doctoral)
Dates
Name
Present Position
01/10-06/11
Andrew Surmak, M.Sc. Ph.D. Medical Physics Program – UCLA
04/12-present Robert Reznik, M.D.
Internal Medicine Resident, CSMC
10/12-01/14
Orr Shauly
Undergraduate student, UCLA
10/13-06/14
Jason Naziri
Undergraduate student, UCLA
01/14-present Arsen Osipov, MD
Internal Medicine Resident, CSMC
09/14-02/15
Dunya Dost
Undergraduate student, UCLA
12/14-present Tina Abramian
Undergraduate student, UCLA
12/14-present Jasleen Khanuja
Internal Medicine Resident, CSMC
03/15-08/15
Navasard Ovasapians Medical student, UCLA
07/15-present
06/16-08/16
06/16-present
Jeffrey Toll
Shant Thomassian
John David
Internal Medicine Resident, CSMC
Medical Student, Meharry
Resident, Radiation Oncology
Invited Lectures/Presentations:
Trabecular Bone-Derived Human Mesenchymal Stem Cells. Sigma Xi Scientific Research
Society, April 5, 2001. Philadelphia PA.
MAP kinase signaling and N-cadherin are critical for chondrogenesis of human tissue progenitor
cells. First Annual Tissue Engineering Meeting, November 21-24, 2002, Cold Spring Harbor
Laboratory
.
Human Bone Marrow Derived Mesenchymal Progenitor Cells Cultured in Biodegradable
Nanofibrous Scaffolds for Tissue Engineering. First Annual Tissue Engineering Meeting,
November 21-24, 2002, Cold Spring Harbor Laboratory.
TGF-β1 Mediated Chondrogenesis of Human Mesenchymal Stem Cells: The Role of MAP Kinase
rd
and Wnt Signaling Crosstalk. AMSA 53 Annual Convention, March 19-23, 2003, Hyatt Regency
Crystal City, Washington D.C.
A Tissue Engineered Osteochondral Construct Based on Human Mesenchymal Stem Cells:
rd
Potential Application for Articular Cartilage Repair. AMSA 53 Annual Convention, March 19-23,
2003, Hyatt Regency Crystal City, Washington D.C.
A tissue engineered osteochondral construct for articular cartilage repair. Sigma Xi Scientific
Research Society, March 27, 2003. Philadelphia PA.
TGF-β1 Mediated Chondrogenesis of Human Mesenchymal Progenitor Cells Involves MAP
Kinase and Wnt Signaling Regulation of N-Cadherin. Sigma Xi Scientific Research Society,
March 27, 2003. Philadelphia PA.
Method Of Detection Of Ipsilateral Breast Tumor Recurrence Following Breast Conserving
Therapy Is A Predictor Of Distant Metastases. American Society for Radiation Oncology.
September 2008. Boston, MA.
Prognostic Indicators Of Ipsilateral Breast Tumor Recurrence Following Breast
Conserving Therapy 10th Annual Meeting, American Society Breast Surgeons, April 2226, 2009. San Diego, CA.
Poly (ADP Ribose) Polymerase-1/2 Inhibition with Veliparib Enhances Radiosensitization
of Pancreas Cancer In Vivo. American Society for Radiation Oncology. October 2011.
Miami, FL.
th
Brachytherapy for Cholangiocarcinoma. 19 International Symposium on Pancreatic &
Biliary Endoscopy. Cedars-Sinai Medical Center, 2012. Los Angeles, CA.
Liver Cancer and Radiotherapy, Stereotactic Body Radiotherapy and Beyond. Liver
st
Tumors in the 21 Century. Cedars-Sinai Medical Center, 2012. Los Angeles, CA.
Grand Rounds - Pancreatic Cancer: Treatment Challenges and New Paradigms. National
Guard Health Administration, 2012. Riyadh, Saudi Arabia.
Grand Rounds – Advances in the Radiotherapeutic Management of Pancreatic Cancer,
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 2013.
Los Angeles, CA.
Pancreatic Cancer Panel: New Approaches to Treatment, Benjamin Center, Cancer
Support Community, 2013. Los Angeles, CA.
Liver & Radiation: Words that Can Go Together. Liver Tumors: New Technologies and
Managements. Cedars-Sinai Medical Center, 2014. Los Angeles, CA.
st
Radiotherapy for Extrahepatic Cholangiocarcinoma. 21 International Symposium on Pancreatic
& Biliary Endoscopy. Cedars-Sinai Medical Center, 2014. Los Angeles, CA.
Pancreatic Adenocarcinoma and Radiotherapy: Where Have We Been and Where are We Going.
Beijing Cancer Hospital, June 2014, Beijing, China.
Treatment Approaches, Controversies and Advances in Radiotherapy for Pancreatic Cancer.
International Hepatopancreatobiliary Forum, Second Affiliate Hospital of Zhejiang University
School of Medicine, June 2014, Hangzhou, China.
Multidisciplinary Management of Pancreatic Adenocarcinoma. Zhong Shan Hospital Fudan
University, June 2014, Shanghai, China.
th
Radiotherapy for Pancreas Cancer: Where are we and where should we be going? 45
Anniversary Meeting of the American Pancreatic Association and Japanese Pancreas Society,
November 2014, Hawaii.
Gastrointestinal Oncology-Integrated Science and Practice Session, Presiding Officer.
Radiological Society of North America – RSNA, December 2014, Chicago.
Neuroendocrine Tumor Patient & Caregiver Educational Conference, Moderator, Caring for
Carcinoid Foundation and LACNETS, June 2015, Los Angeles.
Role of Stereotactic Radiotherapy in Treatment of Abdominal Tumors. American Hospital in
Dubai, October 2015, Dubai, UAE.
Gastrointestinal Tumors – Radiation Oncology Program, Presiding Officer and Poster Host.
Radiological Society of North America – RSNA, November 2015, Chicago. IL.
Advances in the Treatment of Pancreatic Cancer. Nevada Oncology Society. November 2015,
Reno, Nevada.
rd
What We Need to Know About Radiation for Pancreatic Cancer? 23 International Symposium
on Pancreatic and Biliary Endoscopy, Cedars-Sinai Medical Center, January 2016, Los Angeles,
CA.
Focus Session Gastrointestinal Cancers. Los Angeles Radiological Society. February 2016,
Pasadena, CA.
Palliative Radiotherapy: Indications and Symptom Management. Supportive Care Medicine
Grand Rounds, July 2016. Cedars-Sinai Medical Center, Los Angeles, CA.
Locally Advanced Pancreatic Adenocarcinoma from the Perspective of the Radiation Oncologist.
Cancer Treatment Centers of America, September 2016, Newnan, GA.
Keynote Speaker - Gastrointestinal Tumors. Radiological Society of North America – RSNA,
November 2016, Chicago. IL.
Bibliography/Publications:
Articles Published in Professional Journals
1. Nöth, U., Tuli, R., Osyczka, A.M., Danielson, K.G., and Tuan, R.S. In Vitro Engineered Cell-Polymer Constructs
Coated with Human Mesenchymal Stem Cells for Cartilage Repair. Tissue Engineering 8:131-144, 2002.
PMID: 11886661.
2. Tuli, R., Seghatoleslami, M.R., Tuli, S., Howard, M.S., Danielson, K.G. and Tuan, R.S. p38 MAP Kinase
Regulation of AP-2 Binding in TGF-β1 Stimulated Chondrogenesis of Human Trabecular Bone-Derived Cells.
Annals of New York Academy of Sciences 961:172-177, 2002. PMID: 12081893.
3. Nöth, U., Osyczka, A.M., Tuli, R., Hickok, N.J., Danielson, K.G., and Tuan, R.S. Multilineage Mesenchymal
Differentiation Potential of Human Trabecular Bone-Derived Cells. J Orthopaedic Research 20(5):1060-1069,
2002. PMID: 12382974.
4. Wang, M.L, Nesti, L.J., Tuli, R., Lazatin, J., Danielson, K.G., Sharkey, P.F, and Tuan, R.S. Titanium Particles
Suppress Expression of Osteoblastic Phenotype in Human Mesenchymal Stem Cells Undergoing Osteogenic
Differentiation. J Orthopaedic Research 20(6):1175-1184, 2002. PMID: 12472226.
5. Tuli, R., Tuli, S., Seghatoleslami, M.R., Wang, M.L., Hozack, W.J., Manner, P.A., Danielson, K.G., and Tuan, R.S.
A Simple, High-Yield Method for Obtaining Multipotential Mesenchymal Progenitors from Trabecular Bone.
Molecular Biotechnology 23(1):37-49, 2003. PMID: 12611268.
6. Tuan, R.S., Boland, G., and Tuli, R. Adult Mesenchymal Stem Cells and Cell-Based Tissue Engineering. Arthritis
Research and Therapy 5:32-45, 2003. PMID: 12716446.
7. Wang, M.L., Tuli, R., Manner, P.A., Sharkey, P.F., Hall, D.J., and Tuan, R.S. Direct and Indirect Induction of
Apoptosis in Human Mesenchymal Stem Cells in Response to Titanium Particles. J Orthopaedic Research
21(4):697-707, 2003. PMID: 12798071.
8. Tuli, R., Tuli, S., Nandi, S., Huang, X., Hozack, W.J., Manner, P.A., Danielson, K.G., Hall, D.J., and Tuan, R.S.
TGF-β1-Mediated Chondrogenesis of Human Mesenchymal Progenitor Cells Involves N-cadherin and MAP
Kinase and Wnt Signaling Crosstalk. J Biological Chemistry 278(42):41227-41236, 2003. PMID: 12893825.
9. Tuli, R., Li, W.J., and Tuan, R.S. Current State of Cartilage Tissue Engineering. Arthritis Research and Therapy
5:235-238, 2003. PMID: 12932283.
10. Tuli, R., Tuli, S., Nandi, S., Wang, M.L., Alexander, P.G., Hozack, W.J., Manner, P.A., Danielson, K.G., and Tuan,
R.S. Characterization of Multipotential Mesenchymal Progenitor Cells Derived from Human Trabecular Bone.
Stem Cells 21:681-693, 2003. PMID: 14595128.
11. *Noth, U., *Tuli, R., Seghatoleslami, R., Howard, M., Shah, A., Hickok, N.J., and Tuan, R.S. Activation of p38 and
Smads Mediates BMP-2 Effects on Human Trabecular Bone-Derived Osteoblasts. Experimental Cell Research
291:201-211, 2003. PMID: 14597420. *These authors contributed equally to this work.
12. Tuli, R., Nandi, S., Li, W.J., Tuli, S., Huang, X., Manner, P.A., Laquerriere, P., Noth, U., Hall, D.J., and Tuan, R.S.
Human Mesenchymal Progenitor Cell-Based Tissue Engineering of a Single-Unit Osteochondral Construct.
Tissue Engineering 10(7-8):1169-1179, 2004. PMID: 15363173.
13. Danielson, K.G., Kanthala, S., Tuli, R., Tuan, R.S. Fluorescent Detection of Differentially Expressed cDNA Using
SYBR Gold Nucleic Acid Gel Stain. Molecular Biotechnology 28(1):41-46, 2004. PMID: 15456962.
14. Li, W.J., Tuli, R., Okafor, C., Derfoul, A., Danielson, K.G., Hall, D.J., and Tuan, R.S. A Three-Dimensional
Nanofibrous Scaffold for Cartilage Tissue Engineering Using Human Mesenchymal Stem Cells. Biomaterials
26(6):599-609, 2005. PMID: 15282138.
15. Li, W.J., Tuli, R., Huang, X., Laquerriere, P., and Tuan, R.S. Multilineage differentiation of human mesenchymal
stem cells in a three-dimensional nanofibrous scaffold. Biomaterials 26(25):5158-5166, 2005. PMID: 15792543.
16. Haleem-Smith, H., Derfoul, A., Okafor, C., Tuli, R., Olsen, D., Hall, D.J., and Tuan, R.S. Optimization of High
Efficiency Transfection of Adult Human Mesenchymal Stem Cells. Molecular Biotechnology 30(1):9-20, 2005.
PMID: 15805572.
17. Tuli, R. and Parvizi, J. Alternative Bearing Surfaces in Total Hip Arthroplasty. Expert Review of Medical Devices
2(4):445-452, 2005. PMID: 16293083.
18. El-Amin, SF., Botchwey, E., Tuli, R., Kofron, M.D., Mesfin, A., Sethuraman, S., Tuan, R.S., and Laurencin, C.T.
Human osteoblast cells: Isolation, characterization, and growth on polymers for musculoskeletal tissue
engineering. Journal of Biomedical Materials Research Part A, 76A(3):439-449, 2006. PMID: 16541483.
19. Tuli, R., Flynn, R.A., Brill, K.L., Sabol, J.L., Usuki, K.Y. and Rosenberg, A.L. Diagnosis, Treatment and
Management of Breast Cancer in Previously Augmented Women. The Breast Journal 12(4):343-348, 2006.
PMID: 16848844.
20. Tuli, R., O’Hara, B.J., Hines, J. and Rosenberg, A.L. Idiopathic Granulomatous Mastitis Masquerading as
Carcinoma of the Breast. International Seminars Surgical Oncology 4(21):1-4, 2007. PMID: 17662130.
21. Tuli, R., Christodouleas, J., Roberts, L., Deol, S.J., Usuki, K.Y., Frassica, D. and Rosenberg, A.L. Prognostic
Indicators Following Ipsilateral Tumor Recurrence in Patients Treated with Breast Conservation Therapy.
American Journal Surgery 198(4):557-561, 2009. PMID: 19800468.
22. Tuli, R. and Herman, J.M. Adjuvant Chemotherapy and Radiation Following Pancreaticoduodenectomy For
Pancreatic Adenocarcinoma: Summary of Trials and Future Directions. American Journal Hematology Oncology
8(3):106-111, 2009.
23. Poultsides, G.A., Huang, L C., Cameron, J.L., Tuli, R., Lan, L., Sugar, E.A., Hruban, R.H., Pawlik, T.M., Herman,
J.M., Edil, B.H., Ahuja, N., Choti, M.A., Wolfgang, C.L. and Schulick, R.D. Duodenal Adenocarcinoma:
Clinicopathologic Analysis and Implications for Treatment. Annals of Surgical Oncology 19(6):1928-35, 2012.
PMID: 22167476.
24. Tuli, R., Surmak, A., Reyes, J., Hacker-Prietz, A., Armour, M., Leubner, A., Blackford, A., Tryggestad, E., Jaffee,
E., Wong, J., DeWeese, T. and Herman, J. Development of a Novel Preclinical Pancreatic Cancer Research
Platform: Bioluminescence-Guided Focal Irradiation and Tumor Monitoring of Orthotopic Xenografts.
Translational Oncology 5(2):77-84, 2012. PMID: 22496923.
25. Qiu, H., Wild, A., Wang, Hao., Fishman, E., Hruban, R.H., Laheru, D., Kumar, R., Hacker-Prietz, A., Tuli, R.,
Tryggestad, E., Schulick, R., Cameron, J.L., Edil, B., Pawlik, T., Wolfgang, C., Herman, J.M. Comparison of
conventional and 3-dimensional computed tomography against histopathologic examination in determining
pancreatic adenocarcinoma tumor size: Implications for radiation therapy planning. Radiotherapy and Oncology.
104(2):167-172, 2012. PMID: 22883106.
26. Jabbour, S., Patel, S., Herman, J., Nagda, S., Moore, D., Chen, C., Chandra, R., Haffty, B.G., Tuli, R. IntensityModulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department
Visits. Int J Surg Onc. 2012:891067, 2012. PMID: 22934164.
27. Rudra, S., Narang, A.K., Pawlik, T.M., Wang, H., Jaffee, E.M., Zheng, L., Le, D.T., Cosgrove, D., Hruban, R.H.,
Fishman, E.K., Tuli, R., Laheru, D.A., Wolfgang, C., Diaz, L.A., Herman, J.M. Evaluation of predictive variables
in locally advanced pancreatic adenocarcinoma patients receiving definitive chemoradiation. Practical Radiation
Oncology 2(2):77-85, 2012. PMID: 23585823.
28. Tuli, R., Armour, M., Surmak, A., Reyes, J., and Wong, J. Accuracy of Off-Line Bioluminescence Imaging to
Localize Targets in Pre-Clinical Radiation Research. Radiat Res. 179(4):416-21, 2013. PMID: 23578189. PMCID:
PMC4347528.
29. Menon, V.G., Puri, V.C., Annamalai, A.A., Tuli, R., Nissen, N.N. Outcomes of Vascular Resection in
Pancreaticoduodenectomy: Single-Surgeon Experience. Am Surg. 79(10):1064-1067, 2013. PMID: 24160800.
30. Sharabi, A., Herman, J., Weiss, V., Laheru, D., Tuli, R. Role of Radiotherapy in Improving the Therapeutic
Efficacy of Chemotherapy, Targeted Therapy, and Immunotherapy in the Management of Pancreatic Cancer.
Journal of Radiation Oncology. 2(4), 2013.
31. Yang, W., Fraass, B., Reznik, R., Nissen, N., Lo, S., Gupta, K., Jamil, L., Sandler, H., Tuli, R. Adequacy of
Inhale/Exhale Breathhold CT based ITV Margins and Image-guided Registration for Free-breathing Pancreas and
Liver SBRT. Radiation Oncology. 9(11), 2014. PMID 24401365.
32. Reznik, R., Hendifar, A., Tuli, R. Genetic Determinants and Potential Therapeutic Targets for Pancreatic
Adenocarcinoma. Frontiers in Gastrointestinal Sciences. 5(87), 2014. PMID 24624093.
33. Tan, C., Yaffee, P., Jamil, L., Lo, S., Nissen, N., Pandol, S., Tuli, R., Hendifar, A. Pancreatic Cancer Cachexia: a
Review of Mechanisms and Therapeutics. Frontiers in Gastrointestinal Sciences. 5(88), 2014. PMID 24624094.
34. Mian, O., Ram, A., Tuli, R., Herman, J. Management Options in Locally Advanced Pancreatic Cancer. Current
Oncology Reports. 16(6), 2014. PMID 24740136.
35. Tuli, R., Surmak, A., Reyes, J., Armour, M., Hacker-Prietz, A., Wong, J., DeWeese, T.L., Herman, J.M.
Radiosensitization of pancreatic cancer cells in vitro and in vivo through poly (ADP ribose) polymerase-1/2
inhibition with ABT-888. Trans Onc. S1936(14), 2014. PMID 24836647.
36. Hendifar, A., Tan, C.R., Annamalai, A., Tuli, R. Biomarker-Driven EFGR Therapy Improves Outcomes in Patients
with Metastatic Colorectal Cancer. Expert Review of Anticancer Therapy. 14(9), 2014. PMID 24898788.
37. Yang, W., Reznik, R., Fraass, B., Nissen, N., Hendifar, A., Wachsman, A., Sandler, H., Tuli, R. Dosimetric
Evaluation of Simultaneous Integrated Boost during Stereotactic Body Radiotherapy for Pancreatic Cancer. Med
Dosim. S0958(14), 2014. PMID 25445989.
38. Yang, W., McKenzie, E., Burnison, M., Shiao, S., Mirhadi, A., Hakimian, B, Reznik, R., Tuli, R., Sandler, H.,
Fraas, B. Clinical experience using a video-guided spirometry system for deep inhalation breath-hold radiotherapy
of left-sided breast cancer. Journal of Applied Clinical Medical Physics. 2015, 16(2):5218. PMID: 26103193.
39. Deng, Z., Pang, J., Yang, W., Yue Y., Sharif, B., Tuli, R., Li, D., Fraass, B., Fan, Z. 4D MRI Using 3D radial
sampling with respiratory respiratory self-gating to characterize temporal phase-resolved respiratory motion in the
abdomen. Magn Reson Med. 2016, 75(4):1574. PMID: 25981762.
40. Yang, W., Fan, Z., Tuli, R., Deng, Z., Pang, J., Wachsman, A., Reznik, R., Sandler, H., Li, D., Fraass, B. Four
dimensional magnetic resonance imaging with 3-dimensional radial sampling and self-gating based K-space
sorting: early clinical experience on pancreatic cancer patients. Int J Radiat Oncol Biol Phys. 93(5):1136-43, 2015.
PMCID: PMC4654642.
41. Yue, Y., Fan, Z., Yang, W., Pang, J., Deng, Z., McKenzie, E., Tuli, R., Wallace, R., Li, D., Fraass, B. Geometric
Validation of self-gating k-space sorted 4D-MRI vs. 4D-CT using a respiratory motion phantom. Medical Physics.
2015, 42(10):5787. PMID: 26429253.
42. Wang, J., Narang, A., Sugar, E., Luber, B., Rosati, L., Hsu, C., Fuller, C., Pawlik, T., Miller, R., Czito, B., Tuli, R.,
Crane, C., Ben-Josef, E., Thomas, C., Herman, J. Evaluation of adjuvant radiation therapy for resected
gallbladder carcinoma: a multi-institutional experience. Ann Surg Oncol. 2015, 22(3):1100. PMID 26224402.
43. Osipov, A., Naziri, J., Hendifar, A., Dhall, D., Rutgers, J., Chorpa, S., Li, Q., TIghiouart, M., Nissen, N., Tuli, R.
Impact of margin status and lymphadenectomy on clinical outcomes in resected pancreatic adenocarcinoma:
implications for adjuvant radiotherapy. Journal Gastrointestinal Oncology. 2016, 7(2):239. PMID 27034792.
44. Jin, J., McKenzie, E., Tuli, R., Fan, Z., Deng, Z., Fraass, B., Li, D., Sandler, H., Gou, S., Yang, W. Non-local
means denoising of SG-KS-4D-MRI using block matching 3D: Implications for pancreatic tumor registration and
segmentation. Int J Radiat Oncol Biol Phys. Int J Radiat Oncol Biol Phys. 2016, 95(3):1058. PMID 27302516.
45. Hendifar, A., Osipov, A., Khanuja, J., Nissen, N., Naziri, J., Yang, W., Li, Q., Tuli, R. Influence of Body Mass
Index and Albumin on Perioperative Morbidity and Clinical Outcomes in Resected Pancreatic Adenocarcinoma.
PLOS One. 2016, 11(3). PMID 27015568.
46. Gong, J., Tuli, R., Shinde, A., Hendifar, A. Meta-analysis of treatment standards in pancreatic cancer. Mol Clin
Oncol. 2016, 4(3):315.
47. Iriana, S., Ahmed, S., Gong, J., Annamalai, A., Tuli, R., Hendifar, A. Targeting mTOR in pancreatic ductal
adenocarcinoma. Frontiers in Oncology. 2016, 6(99). PMID 27200288.
48. Yue, Y., Osipov, A., Fraass, B., Sandler, H., Zhang, X., Nissen, N., Hendifar, A., Tuli, R. Identifying Prognostic
Intratumor Heterogeneity using Multiphase 18F-FDG PET Images for Pancreatic Cancer Patients Treated with
Radiotherapy. Journal Gastrointestinal Oncology. In press.
49. Hendifar, A., Davies, L., Rahib, L., Zhang, X., Aizenberg, R., McCurrach, M., Morin, P., Martisian, L.M., Tuli, R.
Private funding for pancreatic cacner research: More than a chipshot. Gastroenterology. In press.
50. Hendifar, A., Marchevsky, A.M., Tuli, R. Neuroendocrine Tumors of the Lung: Current Challenges and Advances
in the Management of Well-Differentiated Disease. J Thoracic Oncology. In press.
Book Chapters
1. Nöth U., Berner A., Tuli, R., Battmann A., Hendrich C., Eulert J., Tuan R.S. Fabrication of cartilage-polymer
constructs for articular cartilage repair. In: Hendrich C, Nöth U, Eulert J (eds). Cartilage surgery and future
perspectives. Springer Verlag, Heidelberg, pp165-170, 2003.
2. Tuli, R.: Management of Bladder Cancer, Metastatic Prostate Cancer and Ovarian Cancer (separate chapters), in
Radiation Oncology: A Question-Based Review, Hristov, B, Lin, S, Christodouleas, J (eds). Lippincott Williams
and Wilkins, Philadelphia, PA. 2011.
3. Tuli, R.: Management of Hepatocellular Cancer, Anal Cancer, Colorectal and Small Bowel Cancer (separate
chapters), in Radiation Oncology (second edition): A Question-Based Review, Hristov, B, Lin, S, Christodouleas, J
(eds). Lippincott Williams and Wilkins, Philadelphia, PA. 2014.