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B – The Cardiovascular System 1. The structure and function of arteries, capillaries and veins 2. The structure and function of the heart 3. Pathology of cardio vascular disease (CVD) 4. Blood glucose levels and obesity KA 6: The structure and function of the heart REVISION: Structure of the heart (A) Cardiac function and cardiac output 2.6 Key Topics (B) Cardiac cycle (D) Blood Pressure (C) The structure and function of cardiac conducting system KA 6a: Learning Outcomes • Define the terms ‘cardiac output’, ‘heart rate’ and ‘stroke volume’ • State the formula for cardiac output • Carry out cardiac output calculations Key Terms Heart Rate (pulse) (HR) • Number of heartbeats that occurs per minute. Stroke Volume (SV) • Volume of blood expelled by each ventricle on contraction. (The stronger the contraction, the greater the stroke volume). Cardiac Output (CO) • The volume of blood pumped through each ventricle per minute. (creates the pulse) • CO = HR x SV The left and right ventricles pump the same volume of blood through the aorta and pulmonary artery. Calculations CO = HR x SV A: 5.8/60 = 0.09 B: 6.1/68 = 0.08 C: 7.2/72 = 0.1 D: 7.6/78 = 0.09 ANSWER: C Calculations CO = HR x SV The graph below shows how pulse rate and stroke volume change with the rate of oxygen uptake 1. What is the cardiac output when the oxygen uptake is 0.6 L/min ? 2. What is the cardiac output when the oxygen uptake is 1.6 L/min? Calculations CO = HR x SV The graph below shows how pulse rate and stroke volume change with the rate of oxygen uptake 1. What is the cardiac output when the oxygen uptake is 0.6 L/min ? When oxygen uptake = 0.6… HR = 80 and SV = 120 • BUT we need to change 120 cm3 into L (/1000) CO = HR x SV CO = 80 x 0.12 CO = 9.6 L/min Calculations CO = HR x SV The graph below shows how pulse rate and stroke volume change with the rate of oxygen uptake 1. What is the cardiac output when the oxygen uptake is 1.6 L/min ? When oxygen uptake = 1.6… HR = 110 and SV = 150 • BUT we need to change 150 cm3 into L (/1000) CO = HR x SV CO = 110 x 0.15 CO = 16.5 L/min KA 6a: Learning Outcomes • Define the terms ‘cardiac output’, ‘heart rate’ and ‘stroke volume’ • State the formula for cardiac output • Carry out cardiac output calculations