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Curriculum Vitae Prof. ADA MARIA TATA PhD, Associate Professor, SSD Bio/06 Teaching experience From 1999: (i) Developmental Biology, (ii) Embryology (iii) Developmental Neuroscience. Author of 47 publications ( original articles and reviews). H index =13 (ISI WEB of Knowledge, SCOPUS) Research topic Acetylcholine effects on normal and pathological glial cells and in the central and peripheral inflammation. Publications 2009-2014 M Salani, T. et al, (2009). Acetylcholine-induced neuronal differentiation: muscarinic receptor activation regulates EGR-1 and REST expression in neuroblastoma cells J. Neurochem. 108:821834; ISSN: 0022-3042; doi: 10.1111/j.1471-4159.2008.05829.x. A.M. Tata, et al. (2009). M2 receptor activation affects servival and proliferation of human glioblastoma cells. International Proceedings: IX European Meeting of the Glial Cells in Health and Disease. Medimomd Ed. V. Magnaghi, et al. (2009). Novel pharmacological approaches to Schwann cells as neuroprotective agents for peripheral nerve regeneration. Int. Rev Neurobiol 87: 295-315. ISSN 0074-7742. 10.1016/S0074-7742(09)87015-3 A.M. Tata (2010). Muscarinic acetylcholine receptors as novel therapeutic targets. In Frontiers in CNS Drug Discovery , Ed. Atta-ur-Rahman and Iqbal Choudhary, Bentham Science, chapter 17: 362-377. ISBN: 9781608051595. A.M. Tata and Calogero A. (2010). Muscarinic receptors and cancer: possible implication in tumor of the nervous system. Curr. Trends Neurol.4 :23-31; ISSN: 0972-8252. Catacuzzeno L., et al. (2011). Serum-activated K and Cl currents underlay U87-MG glioblastoma cell migration. J. Cell Physiol.226: 1926-1933; ISSN: 0021-9541; doi: 10.1002/jcp.22523. E Piccinni, A. et al. (2011). Direct interaction of Gas41 and Myc, two amplified genes in nervous system tumours. Acta Biochimica Polonica, vol. 58: 529.534; ISSN: 0001-527X. De Angelis F., et al. (2012). Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation and differentiation. Dev. Neurobiol. 72: 713-728; ISSN 1932-8451; doi: 10.1002/dneu.20976 Ferretti M, et al. (2012). M2 muscarinic receptor inhibits cell proliferation in human glioblastoma cell lines. Life Sciences, 91: 1134-1137. ISSN: 0024-3205; 10.1016/j.lfs.2012.04.033 Corsetti V., et al. (2012). Acetylcholine release: the mechanisms and the site of release during chick dorsal root ganglia ontogenesis. Life Sciences, 91: 783-788; ISSN 0024-3205; doi: .10.1016/j.lfs.2012.08.026. Reale M, et al. (2012). Relation Between Pro-Inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients. Int. J. Mol. Sci. 2012, 13, 12656-12664; ISSN: 1422-0067; doi:10.3390/ijms131012656 Sara Marinelli, et al. (2012). The analgesic effect on neuropathic pain of retrogradelly transported Botulinum neurotoxin A involves Schwann cells and astrocytes. PlosOne 7, e4797. ISSN: 19326203; doi: 10-371/journal.pone.0047977. Ferretti M, et al. (2013). M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells. J Cell Mol Med., 17(4): 552-566; ISSN: 1582-1838; doi: 10.1111/jcmm.12038. Reale M, Tata AM, 2013 Editorial (Modulation of cholinergic system activity in neuronal and non-neuronal tissues: therapeutic implications). Antiinflamm Antiallergy Agents Med Chem. 12(2):107-108. ISSN 18715230. Greig NH, Reale M and Tata AM. (2013). New pharmacological approaches to the cholinergic system: an overview on muscarinic receptor ligands and cholinesterase inhibitors. Rec. Pat. CNS Drug Discov. 8 (2):123-141. ISSN: 1574-8898; doi: 10.2174/1574889811308020003. De Stefano ME, et al. (2013). Therapeutic approaches enhancing peripheral nerve regeneration. Advances Biosci and Biotech. 4: 53-60. ISSN 2156-8456. Doi: 10.4236/abb.2013.46A008 Federica De Angelis, et al. (2014). M2 receptors exert analgesic action on DRG sensory neurons by negatively modulating VR1 activity. J Cell Physiol; vol 229: 783-790; ISSN 0021-9541; doi: 10.1002/jcp.24499. Carolina Uggenti, et al. (2014). M2 muscarinic receptor activation addresses Schwann cell differentiation and myelin organization. Dev. Neurobiol. ISSN: 1932-846X; doi: 10.1002/dneu.22161.