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Circulatory System 1H08.01 Explain the structure of the heart. A. Size, shape and location 1. Size of closed fist 2. In thoracic cavity 3. Apex 4. Four chambers B. Layers 1. Pericardium 2. Myocardium 3. Endocardium 4. Septum C. Structures to and from heart 1. Superior and inferior vena cava 2. Pulmonary artery and vein 3. Aorta D. Chambers and valves 1. Atria (atrium) 2. Ventricles (ventricle) 3. Tricuspid valve 4. Mitral (bicuspid) valve 5. Pulmonary semilunar valve 6. Aortic semilunar valve 1H08.02 Analyze the function of the heart. A. Four main functions of circulatory system a. Pump b. Blood transport system around body c. Carries oxygen and nutrients to cells, carries away waste products d. Lymph system – returns excess tissue fluid to general circulation B. Heart a. Ave. 72 beats per minute, 100,000 beats per day b. Superior and inferior vena cava bring deoxygenated blood to right atrium c. Cardiopulmonary circulation – circulation from the heart to the lungs d. Pulmonary artery takes blood from right ventricle to lungs e. Pulmonary veins bring oxygenated blood from lungs to left atrium f. Aorta takes blood from left ventricle to rest of body g. Four heart valves permit flow of blood in one direction C. Pump a. Heart is a double pump b. Right heart = right atrium tricuspid valve right ventricle pulmonary semilunar valve pulmonary artery lungs (for oxygen) c. Left heart = Lungs pulmonary veins left atrium mitral valve left ventricle aortic semilunar valve aorta general circulation D. Heart sounds (lubb dupp) E. Electrical activity a. SA (sinoatrial) node = pacemaker, sends out electrical impulses, spreads impulse over atria and makes them contract b. AV (atrioventricular) node = carries impulse to bundle of His Summer 2005 H.1 c. Bundle of His = conducting fibers in septum, divides into right and left branches in ventricles to Purkinje fibers d. Purkinje fibers = cause ventricles to contract 1H08.03 Analyze circulation and the blood vessels A. Cardiopulmonary circulation – carries blood from heart to lungs 1. Oxygenated and deoxygenated blood 2. Oxygen/carbon dioxide exchange B. General circulation 1. Coronary arteries 2. Aorta 3. Systemic circulation C. Blood vessels 1. Arteries a. Carry oxygenated blood away from the heart to the capillaries b. Elastic, muscular and thick-walled c. Transport blood under very high pressure 2. Arterioles 3. Veins a. Carry deoxygenated blood away from capillaries to heart b. Less elastic and muscular than arteries c. Thin walled, collapse easily when not filled with blood d. Superior and inferior vena cava carry blood to heart 4. Venules 5. Capillaries a. Smallest blood vessels b. Only seen with microscope c. Connect arterioles and venules e. Walls are one-cell thick, allow for selective permeability 6. Valves – permit flow of blood only in direction of heart 7. Capillaries 8. Jugular vein – located in neck 9. Carotid artery – carries blood to brain D. Blood pressure 1. Systolic – ave = 120 (Systole is contraction phase) 2. Diastolic – ave = 80 (Diastole is relaxation phase) E. Pulse – alternating expansion and contraction of an artery as blood flows through it 1. Brachial 2. Carotid 3. Femoral 4. Pedal 5. Popliteal 6. Radial Summer 2005 H.2 1H08.04 Discuss characteristics and treatment of common cardiac and circulatory disorders. A. Heart diseases 1. Symptoms a. Arrythmia (dysrrhythmia) – any change from normal heart rate or rhythm b. Bradycardia – slow heart rate (<60) c. Tachycardia – rapid heart rate (>100) 2. Coronary artery disease a. Angina pectoris – chest pain, lack of O2 to heart muscle, treat with nitroglycerine b. Edema – fluid in tissues, often caused by poor circulation 3. Myocardial infarction (MI, heart attack) a. Lack of blood supply to myocardium b. Symps – severe chest pain radiating to left shoulder, arm, neck and jaw, nausea, diaphoresis, dyspnea c. Rx – bedrest, oxygen, medication d. Morphine for pain e. Anticoagulant therapy to prevent further clots from forming f. Surgery may be necessary B. Vascular diseases 1. Aneurysm – ballooning of an artery, thinning and weakening 2. Arteriosclerosis – arterial walls thicken and lose elasticity 3. Atherosclerosis – fatty deposits form on walls of arteries and block circulation 4. Hypertension a. High blood pressure b. Silent killer – usually no symptoms c. Leads to strokes, heart attacks, kidney failure d. Higher in African-Americans and post-menopausal women e. Risk factors – smoking, overweight, stress, high fat diets, family history f. Treatment – relaxation, low fat diet, exercise, weight loss, medication 5. Hypotension – low blood pressure, systolic <100 6. Embolism – traveling blood clot 7. Varicose veins a. Swollen, distended veins b. Heredity or due to poor posture, prolonged periods of standing, physical exertion, age and pregnancy C. Diagnosis and treatment 1. Electrocardiogram – electrical tracing of the heart 2. Coronary bypass – healthy vein from leg removed and attached before and after the coronary obstruction, creating an alternate route for blood supply to the myocardium 3. AED – automated external defibrillator 4. Defibrillation – electrical shock to bring the heart back to a normal rhythm 5. CPR – cardiopulmonary resuscitation, used in presence of cardiac arrest 6. Artificial pacemaker – when heart has conduction (electrical impulse) defect, demand pacemaker fires when heart rate drops below minimum, causes heart to contract 7. Angiogram – x-ray of blood vessel using dye Summer 2005 H.3 Unit H: Circulatory System Terminology List 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. aorta aortic semilunar valve apex arterioles artery atrium Atrioventricular (AV) node bicuspid/mitral brachial Bundle of His capillaries carotid cardiopulmonary circulation coronary arteries deoxygenated diastolic endocardium femoral inferior vena cava jugular lubb dupp myocardium 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. Disorders and Related Terminology 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. AED/defibrillation aneurysm angina pectoris angiogram arrhythmias arteriosclerosis artificial pacemaker atherosclerosis bradycardia coronary bypass coronary artery disease CPR edema electrocardiogram (EKG and ECG) embolus (embolism) hypertension hypotension myocardial infarction tachycardia varicose veins Summer 2005 H.4 oxygen/carbon dioxide exchange oxygenated pacemaker pedal pericardium popliteal pulmonary artery pulmonary semilunar valve pulmonary vein pulse sites purkinje fibers radial Sinoatrial (SA) node septum superior vena cava systemic circulation systolic tricuspid valves veins ventricle venules Functions 1. Pump 2. Blood transport system around body 3. Carries O2 and nutrients to cells, carries away waste products 4. Lymph system – returns excess tissue fluid to general circulation Structure – Circulatory system involves: Heart Arteries Veins Capillaries Blood and lymph are part of circulatory system Major Blood Circuits General (Systemic) circulation Cardiopulmonary circulation Summer 2005 H.5 Summer 2005 H.6 The Heart Muscular organ Size of a closed fist Weighs 12-13 oz Location – thoracic cavity APEX – conical tip, lies on diaphragm, points left Stethoscope – instrument used to hear the heartbeat Structure Hollow, muscular, double pump that circulates blood At rest = 2 oz blood with each beat, 5 qts./min., 75 gallons per hour Ave = 72 beats per minute 100,000 beats per day PERICARDIUM – double layer of fibrous tissue that surrounds the heart MYOCARDIUM – cardiac muscle tissue ENDOCARDIUM – smooth inner lining of heart Summer 2005 H.7 SEPTUM – partition (wall) that separates right half from left half Superior vena cava and inferior vena cava – bring deoxygenated blood to right atrium Pulmonary artery – takes blood away from right ventricle to the lungs for O2 Pulmonary veins – bring oxygenated blood from lungs to left atrium Aorta – takes blood away from left ventricle to rest of the body Chambers and Valves SEPTUM divides into R and L halves Upper chambers – RIGHT ATRIUM and LEFT ATRIUM Lower chambers – RIGHT VENTRICLE and LEFT VENTRICLE Four heart valves permit flow of blood in one direction Summer 2005 H.8 TRICUSPID VALVE – between right atrium and right ventricle BICUSPID (MITRAL) VALVE – between left atrium and left ventricle Semilunar valves are located where blood leaves the heart - PULMONARY SEMILUNAR VALVE and AORTIC SEMILUNAR VALVE Summer 2005 H.9 PHYSIOLOGY OF THE HEART The heart is a double pump. When the heart beats… Right Heart Deoxygenated blood flows into heart from vena cava right atrium tricuspid valve right ventricle pulmonary semilunar valve pulmonary artery lungs (for oxygen) Left Heart Oxygenated blood flows from lungs via pulmonary veins left atrium mitral valve left ventricle aortic semilunar valve aorta general circulation (to deliver oxygen) Summer 2005 H.10 Blood Supply to the Heart – from CORONARY ARTERIES Heart Sounds = lubb dupp Summer 2005 H.11 Control of Heart Contractions SA (sinoatrial) NODE = PACEMAKER Located in right atrium SA node sends out electrical impulse Impulse spreads over atria, making them contract Travels to AV Node AV (atrioventricular) NODE Conducting cell group between atria and ventricle Carries impulse to bundle of His BUNDLE OF HIS Conducting fibers in septum Divides into R and L branches to network of branches in ventricles (Purkinje fibers) PURKINJE FIBERS Impulse shoots along Purkinje fibers causing ventricles to contract Summer 2005 H.12 ELECTROCARDIOGRAM (EKG or ECG) Device used to record the electrical activity of the heart. SYSTOLE = contraction phase DIASTOLE = relaxation phase Baseline of EKG is flat line P = atrial contration QRS = ventricular contract T = ventricular relaxation Summer 2005 H.13 CARDIOPULMONARY CIRCULATION – heart and lungs SYSTEMIC CIRCULATION – from the heart to the tissues and cells, then back to the heart Cardiopulmonary Circulation “As the Blood Flows” Appendix MD08.03A ARTERIOLES – small arteries VENULES – small veins Systemic Circulation AORTA – largest artery in the body First branch is coronary artery Aortic arch Many arteries branch off the descending aorta Summer 2005 H.14 Blood Vessels Summer 2005 H.15 ARTERIES Carry oxygenated blood away from the heart to the capillaries Elastic, muscular and thick-walled Transport blood under very high pressure CAPILLARIES Smallest blood vessels, can only be seen with a microscope Connect arterioles with venules Walls are one-cell thick and extremely thin – allow for selective permeability of nutrients, oxygen, CO2 and metabolic wastes VEINS Carry deoxygenated blood away from capillaries to the heart Veins contain a muscular layer, but less elastic and muscular than arteries Thin walled veins collapse easily when not filled with blood VALVES – permit flow of blood only in direction of the heart JUGULAR vein – located in the neck Summer 2005 H.16 Blood Pressure Surge of blood when heart pumps creates pressure against the walls of the arteries SYSTOLIC PRESSURE – measured during the contraction phase DIASTOLIC PRESSURE – measured when the ventricles are relaxed Average systolic = 120 Average diastolic = 80 PULSE – alternating expansion and contraction of an artery as blood flows through it. Pulse sites: BRACHIAL CAROTID RADIAL POPLITEAL PEDAL Summer 2005 H.17 Diseases of the Heart ARRHYTHMIA (or dysrrhythmia) – any change from normal heart rate or rhythm BRADYCARDIA – slow heart rate (<60 bpm) TACHYCARDIA – rapid heart rate (>100 bpm) Coronary Artery Disease ANGINA PECTORIS – chest pain, caused by lack of oxygen to heart muscle, treat with nitroglycerin to dilate coronary arteries MYOCARDIAL INFARCTION MI or heart attack Lack of blood supply to myocardium causes damage Due to blockage of coronary artery or blood clot atherosclerosis – plaque build-up on arterial walls, or arteriosclerosis – loss of elasticity and thickening of wall. Amount of damage depends on size of area deprived of oxygen Summer 2005 H.18 Symptoms – severe chest pain radiating to left shoulder, arm, neck and jaw. Also nausea, diaphoresis, dyspnea. Immediate medical care is critical Rx – bedrest, oxygen, medication Morphine for pain, tPA to dissolve clot Anticoagulant therapy to prevent further clots from forming Angioplasy and by-pass surgery may be necessary Heart Surgery CORONARY BY-PASS – usually, a healthy vein from the leg removed and attached before and after the coronary obstruction, creating an alternate route for blood supply to the myocardium. PACEMAKERS Demand pacemaker – fires only when heart rate drops below programmed minimum CPR – cardiopulmonary resuscitation, used in the presence of cardiac arrest Summer 2005 H.19 DEFIBRILLATION – electrical shock to bring the heart back to a normal rhythm. AED – automated external defibrillator Disorders of the Blood Vessels ANEURYSM – ballooning of an artery, thinning and weakening ARTERIOSCLEROSIS – arterial walls thicken, lose elasticity ATHEROSCLEROSIS – fatty deposits form on walls of arteries EMBOLISM – traveling blood clot VARICOSE VEINS – swollen, distended veins – heredity or due to posture, prolonged periods of standing, physical exertion, age and pregnancy Summer 2005 H.20 HYPERTENSION High blood pressure “silent killer” – usually no symptoms Condition leads to strokes, heart attacks, and kidney failure 140/90 or higher Higher in African-Americans and postmenopausal women Risk factors = smoking, overweight, stress, high fat diets, family history Treatment = relaxation, low fat diet, exercise, weight loss, medication HYPOTENSION – low blood pressure, systolic <100 Diagnostic Tests CARDIAC CATHETERIZATION – catheter fed into heart, dye injected, x-rays taken as dye moves through coronary arteries STRESS TESTS – determine how exercise affects the heart, pt. on treadmill or exercise bike while electrocardiogram recorded ANGIOGRAM – x-ray of a blood vessel using dye Summer 2005 H.21