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Infectious Diseases At A Glance Last Updated: June 2016 Highlights • • • • • • • • • The rates of all reported infectious diseases combined are highest among youth and young adults aged 15 to 29 years and also among older adults 90 years and older. The rate of enteric illness is higher in the northern municipalities of Durham Region (Brock, Scugog and Uxbridge combined) in most years while all other municipalities have rates similar to Durham Region as a whole. Rates of salmonellosis have been increasing in both Durham Region and Ontario since 2003. The rate of influenza was higher in the northern municipalities of Durham Region (Brock, Scugog and Uxbridge combined) in 2013, 2014 and 2015 compared to Durham Region as a whole. Although chlamydia rates decreased between 2011 and 2013 among both Durham Region and Ontario females and levelled off among Durham Region males, rates increased again between 2014 and 2015 The rate of chlamydia is higher most years in Ajax, Pickering, and Oshawa than Durham Region as a whole, and lower in Whitby, Clarington, and the northern municipalities (Brock, Scugog and Uxbridge combined). Incidence rates of gonorrhea have been increasing since 2009 in both Durham Region and Ontario, especially among males. The rate of hepatitis C infection is consistently higher in Oshawa than in other Durham Region municipalities, and higher than in Durham Region as a whole. Rates for all reportable infectious diseases included in the report are either similar or lower in Durham Region compared to Ontario. Introduction Ontario's Health Protection and Promotion Act requires that a number of infectious diseases be reported to the local Medical Officer of Health by physicians, nurses, other regulated health professionals, hospitals, and laboratories.[1] The Durham Region Health Department investigates and manages identified cases and contacts of infectious diseases and enters them into the integrated Public Health Information System (iPHIS) in accordance with the Ministry of Health and Long-Term Care's Infectious Disease Protocol.[2] The most common source of case identification is through laboratory notification of confirmed test results. There may be considerable under-reporting of cases because an infected person with mild or no clinical symptoms may not seek medical care and/or laboratory testing may not be performed. A list of reportable infectious diseases is available at www.durham.ca/departments/health/disease_prevention/reportableDiseaseList.pdf. Page 1 of 47 This report includes confirmed cases, unless otherwise noted, of reportable infectious diseases according to provincial case definitions provided in the Infectious Disease Protocol.[3] Probable cases are included along with confirmed cases for some diseases (noted in the comments below each graph where relevant) from 2009 onward, to enable comparison to previous years as a result of changes to case definitions in 2009. For all indicators, data are analyzed by the residence of the case at time of diagnosis. This report includes indicators with relevance to public health programming and/or referenced in the Ontario Public Health Standards (OPHS).[4] The current OPHS were published in 2008 by the Ministry of Health and Long-Term Care under the authority of Section 7 of the Health Protection and Promotion Act.[1] Charts and tables are provided for the following indicators for Durham Region: • • • • • • • • • • • • • • • • • • All Reportable Infectious Diseases: Crude Incidence Rate; Age-Specific Incidence Rate. All Enteric Diseases: Incidence Rate; Age-Specific Incidence Rate; Incidence Rate by Municipality Campylobacter Enteritis: Age-Standardized Incidence Rate; Incidence Rate by Municipality Giardiasis: Incidence Rate Salmonellosis: Incidence Rate; Incidence Rate by Municipality All Vaccine Preventable Diseases: Incidence Rate Influenza: Incidence Rate; Age-Specific Incidence Rate; Incidence Rate by Municipality Pertussis: Incidence Rate; Age-Specific Incidence Rate Invasive Pneumococcal Disease (IPD): Incidence Rate All STIs and Bloodborne Infections: Incidence Rate Chlamydia: Incidence Rate; Age-Specific Incidence Rate; Age-Specific Incidence Rate Among Youth 15-19 Years of Age, Adults 20-24 Years of Age, and Adults 25-29 Years of Age; Incidence Rate by Municipality Gonorrhea: Incidence Rate; Age-Specific Incidence Rate; Incidence Rate by Municipality Syphilis: Incidence Rate Hepatitis B, Chronic: Incidence Rate Hepatitis C: Incidence Rate; Incidence Rate by Municipality Latent Tuberculosis Infection (LTBI): Incidence Rate; Incidence Rate by Municipality Age-Standardized Incidence Ratios for Selected Reportable Diseases (Males, Females, & Both Sexes Combined) Number of Confirmed Cases of Selected Reportable Diseases in Durham Among Both Sexes For more detailed, topic specific reports that include infectious disease data please go to the Health Statistics in Durham Region webpage found at durham.ca/healthstats. For more information or if you require this information in an accessible format, please contact the Durham Health Connection Line at 905-666-6241 or 1-800-841-2729. Page 2 of 47 Definitions Definition: Age-Standardized Incidence Ratio (SIR) The ratio of the number of cases observed in the population of interest to the number of cases that would be expected if the population had the same age-specific incidence rates as a standard population. Ontario is used here as the standard population. Since statistical estimates may be unstable when the number of events is small, confidence intervals (CIs) are used to determine whether an SIR is statistically different from 1. 95% CIs are represented in the report by upright bars. If these bars cross 1 this means that the Durham incidence rate is no different from Ontario. An SIR and CIs greater than 1 indicate that the incidence rate is higher in Durham than Ontario, whereas an SIR and CIs less than 1 indicate that incidence is lower in Durham. Definition: Incidence Rate The total number of cases per 100,000 population. This rate depicts the "true" picture of disease in a community. Definition: Age-Specific Incidence Rate The total number of cases in a specified age group per 100,000 population in that age group. The numerator and denominator refer to the same age group. For some indicators, the count of total cases displayed is more than the sum of male and female cases as a result of unspecified or other gender. Page 3 of 47 All Reportable Infectious Diseases All reportable infectious diseases are included in these rates with the exception of adverse vaccine events; chickenpox (varicella); Clostridium difficile infection; gastroenteritis, institutional outbreaks; & respiratory infection outbreaks in institutions. Institutions include: long-term care homes, hospitals, retirement homes, daycares and schools. Page 4 of 47 Figure 1: All Reportable Infectious Diseases Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 251.5 334.3 313.9 412.2 558 746 1,304 1994 250.0 338.3 341.5 421.1 566 773 1,339 1995 249.3 319.8 410.7 447.6 576 746 1,322 1996 233.1 305.1 345.1 363.9 547 725 1,272 1997 182.7 257.7 317.7 333.8 439 627 1,066 1998 246.5 330.7 357.1 375.6 606 823 1,427 1999 178.3 271.5 338.0 357.5 447 690 1,137 2000 176.6 248.2 338.1 363.2 453 646 1,099 2001 191.1 283.9 331.3 345.6 500 755 1,252 2002 225.6 315.5 362.7 392.0 602 856 1,457 2003 290.2 348.3 373.8 397.2 792 967 1,759 2004 264.5 337.4 353.9 374.4 737 958 1,696 2005 303.7 376.8 410.0 430.5 863 1,091 1,955 2006 320.9 379.9 397.3 412.9 928 1,121 2,050 2007 320.1 381.0 405.0 424.0 939 1,145 2,084 2008 334.3 430.6 416.7 470.8 993 1,316 2,312 2009 386.0 481.7 491.6 550.8 1,159 1,492 2,653 2010 340.7 469.0 425.4 495.6 1,037 1,476 2,514 2011 366.8 502.5 452.9 537.1 1,129 1,603 2,736 2012 398.5 511.9 496.8 572.4 1,245 1,657 2,902 2013 409.8 459.1 481.0 512.2 1,298 1,507 2,805 2014 428.5 473.7 535.0 562.1 1,375 1,576 2,951 2015 410.4 484.5 536.0 565.7 1,332 1,630 2,963 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Crude reportable infectious disease incidence rates have been increasing fairly steadily since 2001 in males and females and are higher among females in both Durham Region and Ontario. Patterns in overall infectious disease rates are influenced most strongly by trends in chlamydia, which has accounted for over half of all reported infectious diseases since 2001 and occurs at a rate of close to two to one among females compared to males. Page 5 of 47 Figure 2: All Reportable Infectious Diseases Age-Specific Incidence Rates, Durham Region and Ontario, 2011-2015 Combined Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 0-4 287.7 216.0 413.8 350.9 259 187 446 5-9 124.3 84.2 189.6 157.2 120 78 198 10-14 15-19 20-24 25-29 30-34 68.5 476.9 1274.6 958.7 514.1 96.9 1395.0 2135.9 1006.4 533.8 119.4 536.6 1365.3 1117.6 748.0 118.9 1527.7 2163.4 1121.6 646.1 71 576 1,506 949 492 96 1,598 2,413 992 553 167 2,175 3,920 1,943 1,045 35-39 373.9 350.1 518.9 415.5 381 385 766 40-44 273.1 258.6 421.8 284.6 303 303 607 45-49 278.9 192.0 367.9 220.2 360 258 618 50-54 261.1 158.4 304.4 197.1 357 217 574 55-59 242.4 171.7 284.1 191.7 266 193 459 60-64 252.8 170.3 266.7 182.5 218 154 372 65-69 209.8 163.4 240.4 185.6 140 118 258 70-74 237.6 173.0 250.4 201.4 107 89 196 75-79 337.2 214.9 324.2 268.1 110 87 197 80-84 398.0 252.2 433.3 379.1 90 81 171 85-89 90+ 538.3 661.9 455.0 785.7 652.6 1170.5 593.7 982.5 64 33 100 99 164 132 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department, April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. The rates of all reported infectious diseases are highest among youth and young adults aged 15 to 29 years and also among older adults 90 years and older. As with overall rates, this distribution is influenced most strongly by the age distribution of chlamydia, which accounted for over half of all reported infectious diseases between 2011 and 2015. Page 6 of 47 Enteric Diseases Enteric diseases are diseases that affect the stomach and intestines. Reportable enteric diseases in Ontario include: amebiasis; botulism; brucellosis; Campylobacter enteritis; cholera; cryptosporidiosis; cyclosporiasis; food poisoning, all causes; giardiasis; hepatitis A; listeriosis; paralytic shellfish poisoning; paratyphoid fever; salmonellosis; shigellosis; trichinosis; typhoid fever; verotoxin-producing Escherichia coli (VTEC) infection; and yersiniosis. Probable cases are included along with confirmed cases for all enteric diseases with the exception of listeriosis, paratyphoid fever and typhoid from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Page 7 of 47 Figure 3: All Enteric Diseases Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 128.5 115.6 157.4 138.1 285 258 543 1994 125.0 120.8 154.8 137.4 283 276 559 1995 123.8 117.9 145.6 128.2 286 275 561 1996 104.0 90.0 130.9 110.1 244 214 458 1997 89.5 89.2 125.9 107.5 215 217 432 1998 77.7 87.6 126.3 109.1 191 218 409 1999 51.1 48.0 100.0 85.6 128 122 250 2000 73.3 60.7 117.1 104.3 188 158 346 2001 78.4 70.3 110.6 88.7 201 187 388 2002 89.3 81.1 106.8 90.6 229 220 449 2003 77.6 59.8 91.0 73.6 199 166 365 2004 75.2 62.3 88.7 71.6 193 177 370 2005 71.7 60.4 97.4 78.4 184 175 359 2006 75.6 66.4 90.9 74.7 194 196 390 2007 89.3 61.9 97.2 77.1 229 186 415 2008 78.7 56.0 93.1 75.6 202 171 373 2009 75.2 54.9 83.6 68.8 193 170 363 2010 70.9 60.4 89.9 71.8 182 190 372 2011 78.7 61.8 87.3 70.7 202 197 399 2012 92.8 64.9 93.5 77.7 238 210 448 2013 89.7 68.8 91.4 72.9 230 226 456 2014 96.7 59.5 93.4 72.8 248 198 446 2015 86.1 55.3 89.4 72.3 221 186 407 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Rates of enteric diseases decreased between 1992 and 1999 in both Durham Region and Ontario, remained relatively stable since 2003. Rates are higher in males than females in most years. Page 8 of 47 Figure 4: All Enteric Diseases Age-Specific Incidence Rates, Durham Region and Ontario, 2011-2015 Combined Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 0-4 116.6 97.0 153.8 134.2 105 84 189 5-9 73.5 43.2 95.2 79.9 71 40 111 10-14 46.3 35.3 66.3 43.5 48 35 83 15-19 59.6 51.5 76.6 58.0 72 59 131 20-24 55.0 74.4 92.5 85.2 65 84 149 25-29 82.8 77.1 102.6 88.0 82 76 158 30-34 70.0 64.7 91.6 73.3 67 67 134 35-39 58.9 56.4 82.4 61.2 60 62 122 40-44 64.9 52.1 78.6 54.5 72 61 133 45-49 70.5 71.4 79.9 58.5 91 96 187 50-54 78.3 61.3 75.3 57.1 107 84 191 55-59 63.8 58.7 71.7 59.5 70 66 136 60-64 89.3 77.4 74.6 62.0 77 70 147 65-69 70.4 65.1 74.3 61.6 47 47 94 70-74 93.3 62.2 70.5 59.4 42 32 74 75-79 95.0 56.8 71.8 60.7 31 23 54 80+ 76.0 43.5 62.1 48.8 30 29 59 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department, April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Many enteric illnesses occur more frequently in infants and young children compared to adults. Rates are higher among males than females in most age groups. Page 9 of 47 Figure 5: All Enteric Diseases Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 43.4 42.5 47.0 38.2 34.3 53.8 61.2 2009 60.5 55.0 59.5 50.7 43.0 96.2 58.4 2010 49.7 49.7 61.3 54.4 49.5 105.4 59.4 2011 68.2 37.7 78.7 64.2 42.0 87.8 63.0 2012 66.8 77.1 61.1 61.2 71.6 100.5 70.0 2013 82.9 73.8 65.0 58.4 84.6 68.3 70.6 2014 65.7 61.2 52.4 71.8 78.1 100.7 68.4 2015 71.7 46.1 59.6 51.2 78.0 90.0 62.0 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. The rate of enteric illness is higher in North Durham (Brock, Scugog and Uxbridge combined) in most years while all other municipalities have rates similar to Durham Region as a whole. Page 10 of 47 Figure 6: Campylobacter Enteritis Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 Durham Male Rate 62.7 65.4 Durham Female Rate 58.3 69.6 Ontario Male Rate 65.7 71.8 Ontario Female Rate 61.1 65.6 Durham Male Cases 139 148 Durham Female Cases 130 159 Durham Total Cases 269 307 1995 66.2 67.3 59.5 56.4 153 157 310 1996 44.8 43.8 52.3 44.7 105 104 209 1997 38.3 46.4 48.3 44.3 92 113 205 1998 38.6 42.2 51.1 42.9 95 105 200 1999 26.7 27.1 37.8 33.2 67 69 136 2000 37.4 28.8 45.6 39.2 96 75 171 2001 46.8 37.2 46.7 37.5 120 99 219 2002 37.8 28.4 41.2 34.6 97 77 174 2003 35.5 26.7 37.2 29.3 91 74 165 2004 32.7 29.2 35.8 28.5 84 83 167 2005 30.0 21.8 34.9 26.3 77 63 140 2006 30.8 25.8 34.2 27.9 79 76 155 2007 32.4 24.0 35.2 27.4 83 72 155 2008 35.5 21.3 34.1 26.8 91 65 156 2009 30.0 22.3 28.7 23.7 77 69 146 2010 21.8 22.6 30.5 23.8 56 71 127 2011 29.2 21.3 31.9 24.6 75 68 143 2012 44.0 21.9 34.5 28.1 113 71 184 2013 42.1 26.5 35.7 27.8 108 87 195 2014 40.1 26.8 34.5 26.4 103 89 192 2015 28.5 16.6 29.3 23.5 73 56 129 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Campylobacter enteritis is one of the leading causes of enteric disease in Ontario and occurs primarily in the summer months.[5] Probable cases of Campylobacter enteritis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Rates of Campylobacter enteritis decreased between 1994 and 2005 in both Durham Region and Ontario, then increased between 2009 and 2012 but have been decreasing again in recent years. Page 11 of 47 Figure 7: Campylobacter Enteritis Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 19.6 16.1 19.0 17.1 14.2 19.7 25.5 2009 29.2 18.3 21.7 20.2 18.6 44.5 23.5 2010 17.3 15.4 19.9 20.7 19.6 33.9 20.3 2011 21.7 7.0 29.9 28.2 15.9 34.0 22.6 2012 26.9 32.0 21.7 28.0 28.0 44.8 28.8 2013 34.0 29.7 26.8 25.4 37.4 34.1 30.1 2014 31.8 24.3 20.5 30.9 30.4 52.2 29.5 2015 23.2 16.5 17.4 14.4 22.4 36.0 19.6 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Probable cases of Campylobacter enteritis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Rates of Campylobacter enteritis are higher in the northern Durham Region municipalities (Brock, Scugog and Uxbridge combined) in most years, while all other municipalities have rates similar to Durham Region as a whole. Page 12 of 47 Figure 8: Giardiasis Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 25.4 21.5 15.5 18.8 18.8 11.1 9.7 6.8 6.4 11.2 8.9 10.0 6.8 10.6 7.7 9.6 8.9 6.1 6.2 8.6 7.9 8.4 8.0 Ontario Rate 28.6 25.0 24.7 23.0 21.2 18.6 17.2 17.1 17.2 15.7 13.2 12.6 13.2 12.3 13.0 12.9 12.1 11.3 10.4 10.9 11.1 10.6 11.2 Durham Male Cases 63 57 32 47 52 23 24 15 16 29 31 34 19 29 32 34 29 23 23 31 22 41 36 Durham Female Cases 50 41 40 42 39 32 25 20 18 31 18 22 20 33 14 24 25 15 16 24 29 14 17 Durham Total Cases 113 98 72 89 91 55 49 35 34 60 49 56 39 62 46 58 54 38 39 55 51 55 53 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Giardiasis is common in Ontario, especially in institutions and daycare centers where children are not yet toilet trained.[5] Probable cases of giardiasis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Due to small numbers, male and female cases are combined to create more stable rates. Rates of giardiasis decreased between 1991 and 2011 in Ontario but have remained relatively stable since; in Durham Region rates decreased between 1992 and 2001 but have remained relatively stable since then. Page 13 of 47 Figure 9: Salmonellosis Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 Durham Male Rate 23.0 22.5 Durham Female Rate 22.0 21.4 Ontario Male Rate 29.8 25.9 Ontario Female Rate 29.3 25.9 Durham Male Cases 51 51 Durham Female Cases 49 49 Durham Total Cases 100 100 1995 21.6 18.4 26.4 25.6 50 43 93 1996 22.6 17.3 24.0 23.8 53 41 94 1997 19.6 14.4 23.3 23.2 47 35 82 1998 1999 2000 17.1 8.8 19.5 22.1 6.7 14.6 28.3 19.9 19.7 30.2 20.0 20.5 42 22 50 55 17 38 97 39 88 2001 19.9 19.9 21.8 20.6 51 53 104 2002 21.8 24.3 20.2 20.2 56 66 122 2003 18.3 15.8 16.1 16.3 47 44 91 2004 15.6 16.6 17.1 16.8 40 47 87 2005 22.2 21.1 23.8 23.8 57 61 118 2006 18.7 21.4 19.4 18.5 48 63 111 2007 30.8 24.6 22.9 22.4 79 74 153 2008 18.3 20.9 19.7 18.8 47 64 111 2009 21.0 19.4 18.2 19.5 54 60 114 2010 25.3 23.2 22.3 21.9 65 73 138 2011 25.3 22.6 20.6 21.1 65 72 137 2012 27.7 24.4 24.9 25.3 71 79 150 2013 23.4 23.8 20.0 20.3 60 78 138 2014 26.1 22.2 25.1 24.6 67 74 141 2015 30.0 22.9 22.8 23.8 77 77 154 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Salmonellosis is the second most common enteric infection in Ontario but it is estimated that only 1% of all infections are ever clinically recognized.[5] Probable cases of salmonellosis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Rates of salmonellosis decreased between 1991 and 2003 in both Durham Region and Ontario but have been increasing since then. Page 14 of 47 Figure 10: Salmonellosis Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 11.9 14.2 13.2 10.5 15.4 7.2 18.2 2009 15.1 17.4 21.7 19.5 9.3 26.7 18.3 2010 21.6 19.9 23.9 18.8 19.6 32.1 22.0 2011 20.6 16.7 29.9 21.2 19.3 17.9 21.6 2012 19.4 28.6 20.9 20.4 28.0 25.1 23.5 2013 20.2 23.8 20.7 20.9 22.0 19.8 21.3 2014 12.7 22.6 19.0 27.7 22.8 21.6 21.6 2015 33.7 17.3 21.1 20.0 31.0 21.6 23.4 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Salmonellosis is the second most common enteric infection in Ontario but it is estimated that only 1% of all infections are ever clinically recognized.[5] Probable cases of salmonellosis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. The rate of salmonellosis is similar in the Durham Region municipalities to Durham Region as a whole. Page 15 of 47 Vaccine Preventable Diseases Vaccine Preventable Diseases (VPDs) are infectious diseases that can be prevented by routine vaccinations, mostly given during childhood. Reportable VPDs include: diphtheria; Haemophilus influenzae B disease, invasive; hepatitis A; hepatitis B; measles; meningococcal disease, invasive; mumps; pertussis; poliomyelitis, acute; rabies (human); rubella; rubella, congenital syndrome; Streptococcus pneumoniae, invasive (invasive pneumococcal disease); and tetanus. Probable cases of invasive pneumococcal disease, measles, mumps, pertussis and rubella are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Page 16 of 47 Figure 11: All Vaccine Preventable Diseases Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 16.9 29.7 29.9 27.3 21.9 20.4 12.7 7.2 7.4 4.5 13.6 18.1 15.5 15.2 18.2 13.8 11.3 10.7 11.3 13.7 9.0 11.0 10.0 Ontario Rate 20.7 33.7 51.7 18.2 16.7 21.4 15.2 9.9 7.7 12.6 14.2 17.0 18.1 21.4 18.2 20.8 16.9 13.8 15.4 21.0 12.8 13.1 15.7 Durham Male Cases 43 67 73 63 54 47 25 19 17 10 44 40 40 48 64 44 36 29 38 44 35 42 29 Durham Female Cases 32 68 66 66 52 54 39 18 22 14 31 62 49 41 44 39 33 37 33 43 23 30 37 Durham Total Cases 75 135 139 129 106 101 64 37 39 24 75 102 89 89 108 83 69 66 71 87 58 72 66 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. All Vaccine Preventable Diseases excludes influenza, due to the sporadic nature of cases, and chickenpox (varicella) due to underreporting issues. Due to small numbers, male and female cases are combined to create more stable rates. Probable cases of invasive pneumococcal disease, measles, mumps, pertussis and rubella are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Large measles outbreaks occurred in Ontario in 1991-92 and 199495 which explains the peaks for those years. Page 17 of 47 Figure 12: Influenza Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 5.8 1.8 4.7 11.4 5.0 26.7 24.8 6.6 8.5 17.1 32.5 4.6 30.7 15.6 17.0 24.4 87.9 11.6 14.4 32.1 35.7 68.9 34.0 Ontario Rate 14.4 8.4 16.1 9.9 7.7 21.6 31.2 13.3 6.6 22.4 40.4 9.9 43.8 23.2 24.6 38.2 117.8 15.6 33.9 67.7 57.5 97.1 78.5 Durham Male Cases 14 5 7 21 12 62 63 17 23 46 89 16 88 56 53 73 264 32 47 96 121 201 93 Durham Female Cases 12 3 15 33 12 70 62 17 22 46 90 10 87 35 48 74 270 40 43 108 109 248 249 Durham Total Cases 26 8 22 54 24 132 125 34 45 92 179 26 176 91 101 147 536 72 90 204 230 450 225 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Influenza is an acute respiratory illness. In Canada, the influenza season usually runs from November to April. Due to small numbers, male and female cases are combined to create more stable rates. The large number of cases for Ontario and Durham Region in 2009 is due to the H1N1 Pandemic in addition the past couple of seasons have also had large numbers of influenza cases. Influenza rates fluctuate from year to year but in general follow the same pattern in Durham Region and Ontario. A summary of influenza activity for each influenza season is provided on the Flu Surveillance page at durham.ca. Page 18 of 47 Figure 13: Influenza Age-Specific Incidence Rates, Durham Region and Ontario, 2011-2015 Combined Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 0-4 106.6 85.5 185.3 152.2 96 74 170 5-9 43.5 30.2 69.7 54.0 42 28 70 10-14 12.5 17.2 29.0 23.4 13 17 30 15-19 14.1 9.6 17.7 20.1 17 11 28 20-24 13.5 15.9 14.4 22.3 16 18 34 25-29 16.2 25.4 18.6 31.2 16 25 41 30-34 19.9 19.3 25.0 39.9 19 20 39 35-39 23.6 20.9 26.6 36.5 24 23 47 40-44 21.6 24.7 28.7 32.3 24 29 53 45-49 19.4 20.1 26.3 28.8 25 27 52 50-54 19.0 24.1 29.9 34.0 26 33 59 55-59 31.9 26.7 35.6 41.2 35 30 65 60-64 37.1 29.9 49.1 46.2 32 27 59 65-69 27.0 38.8 56.2 59.3 18 28 46 70-74 53.3 36.9 85.6 79.7 24 19 43 75-79 107.3 86.5 154.0 142.6 35 35 70 80-84 181.3 124.5 259.7 250.4 41 40 81 85-89 277.5 327.6 466.9 465.5 33 72 105 90+ 441.2 674.5 950.4 855.8 22 85 107 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department, April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Influenza is an acute respiratory illness. In Canada, the influenza season usually runs from November to April. In general, young children and the elderly have higher incidence rates of influenza. Page 19 of 47 Figure 14: Influenza Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 15.2 12.3 16.5 9.9 61.5 21.5 24.0 2009 92.9 84.4 89.3 66.4 120.8 64.1 86.2 2010 10.8 9.9 6.4 11.0 16.1 0.0 11.5 2011 7.6 7.9 13.4 12.2 11.4 7.2 14.2 2012 30.1 21.6 20.9 32.5 57.0 39.5 31.9 2013 28.7 31.4 35.2 36.8 34.1 53.9 35.5 2014 46.6 55.3 62.3 73.0 86.8 111.5 69.0 2015 27.4 18.9 16.6 46.2 39.5 77.4 34.2 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Influenza is an acute respiratory illness. In Canada, the influenza season usually runs from November to April. The rate of influenza was higher in Clarington in 2008, 2009 and 2012 and higher in the North Durham (Brock, Scugog and Uxbridge combined) in 2013, 2014 and 2015, while all other municipalities have rates similar to Durham Region as a whole. Page 20 of 47 Figure 15: Pertussis Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 5.6 21.5 19.8 19.7 18.2 16.8 11.1 5.2 5.3 2.0 4.4 8.5 7.1 9.1 8.6 5.5 1.3 0.0 0.6 3.1 1.1 2.0 2.6 Ontario Rate 8.6 21.0 18.8 6.5 9.3 16.4 10.6 6.1 3.9 4.4 2.9 5.1 5.2 10.1 7.4 6.7 3.2 1.0 2.2 8.3 2.2 2.3 5.6 Durham Male Cases 15 47 43 42 44 37 22 12 10 3 15 14 16 27 27 17 3 0 4 5 4 6 5 Durham Female Cases 10 51 49 51 44 46 34 15 18 8 9 34 25 26 24 16 5 0 0 15 3 7 12 Durham Total Cases 25 98 92 93 88 83 56 27 28 11 24 48 41 53 51 33 8 0 4 20 7 13 17 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Pertussis, or whooping cough, is an acute bacterial infection that is characterized by violent coughing which may include a high pitched inspiratory whoop.[5] A booster of Tdap vaccine, which protects individuals against tetanus, diphtheria and pertussis, was added to the Ontario routine immunization schedule for 14-16 year olds in 2003.[6] Probable cases of pertussis are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Due to small numbers, male and female cases are combined to create more stable rates. Rates of pertussis have fluctuated over time with Durham Region and Ontario typically showing a similar pattern. Page 21 of 47 Figure 16: Invasive Pneumococcal Disease Incidence Rates, Durham Region and Ontario, 2003-2015 Rates and Cases Durham Rate Ontario Rate Durham Male Cases Durham Female Cases Durham Total Cases 2003 7.3 8.1 26 14 40 2004 8.4 8.5 23 24 47 2005 7.7 7.4 24 20 44 2006 4.1 7.6 12 12 24 2007 7.7 7.6 30 16 46 2008 7.1 8.5 22 21 43 2009 8.4 10.0 27 24 51 2010 9.0 9.6 25 31 56 2011 8.9 10.1 29 27 56 2012 9.0 10.2 35 22 57 2013 7.0 8.3 26 19 45 2014 7.3 8.7 29 19 48 2015 6.5 8.1 20 23 43 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2003-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2003-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2003-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Invasive pneumococcal disease (IPD) is caused by the bacterium Streptococcus pneumoniae and can cause serious illnesses such as pneumonia, blood infection, and meningitis.[5] The pneumococcal conjugate vaccine was added to the routine immunization schedule in 2005 for children less than 2 years old and high-risk children less than 5 years old.[6] Probable cases of IPD are included along with confirmed cases from 2009 onward to enable comparison to previous years as a result of a change in case definition in 2009. Due to small numbers, male and female cases are combined to create more stable rates. Data prior to 2003 are excluded due to inconsistent reporting. Rates in both Durham Region and Ontario increased slightly between 2005 and 2012 and have decreased since. Page 22 of 47 Sexually Transmitted and Bloodborne Infections Sexually transmitted infections (STIs) and bloodborne infections are transmitted primarily from person-to-person through sexual contact, needle use, blood transfusion, and perinatally from mother to infant.[7] Reportable STIs and bloodborne infections in Ontario include: chlamydial infections; gonorrhea; group B streptococcal disease, neonatal; hepatitis B; hepatitis C; human immunodeficiency virus (HIV) / acquired immunodeficiency syndrome (AIDS); ophthalmia neonatorum; and syphilis. HIV data is not available for Ontario prior to 2005 so only AIDS data is included in all STI and Bloodborne Infection totals for those years. Page 23 of 47 Figure 17: All Sexually Transmitted and Bloodborne Infections Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 90.6 196.7 120.5 240.8 201 439 640 1994 83.5 183.0 139.0 242.9 189 418 607 1995 89.2 166.8 194.3 252.6 206 389 595 1996 87.4 170.0 177.1 227.0 205 404 609 1997 60.3 138.1 155.9 201.2 145 336 481 1998 116.8 188.0 180.5 219.1 287 468 755 1999 84.6 179.4 181.3 223.4 212 456 668 2000 84.6 169.8 185.2 232.7 217 442 659 2001 93.6 188.8 191.8 242.6 240 502 742 2002 119.3 205.3 205.5 261.4 306 557 863 2003 166.1 238.4 215.9 267.5 426 662 1,088 2004 182.8 244.7 227.9 277.1 469 695 1,165 2005 208.5 263.9 240.6 275.1 535 764 1,299 2006 240.9 284.7 252.4 288.2 618 840 1,459 2007 223.7 282.8 257.9 301.2 574 850 1,424 2008 256.1 331.2 263.6 337.0 657 1,012 1,672 2009 254.1 327.0 276.4 359.3 652 1,013 1,665 2010 298.2 378.1 306.3 405.9 765 1,190 1,956 2011 315.7 409.4 322.0 434.2 810 1,306 2,120 2012 321.6 393.2 327.5 428.0 825 1,273 2,098 2013 331.3 341.5 334.2 394.9 850 1,121 1,971 2014 332.9 319.8 363.3 410.1 854 1,064 1,918 2015 370.7 369.4 390.3 434.9 951 1,243 2,195 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. The rates of sexually transmitted and bloodborne infections have been increasing in Durham Region and Ontario since 1997. Although there was a decrease between 2011 and 2013 among Durham Region and Ontario females, rates have begun to increase again since. Page 24 of 47 Figure 18: Chlamydia Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 Durham Male Rate 52.7 50.8 39.0 36.2 33.3 48.8 Durham Female Rate 171.2 152.3 126.5 134.7 118.8 140.6 Ontario Male Rate 67.3 61.7 53.9 47.7 50.3 66.1 Ontario Female Rate 197.4 187.5 164.1 143.2 136.6 150.4 Durham Male Cases 117 115 90 85 80 120 Durham Female Cases 382 348 295 320 289 350 Durham Total Cases 499 463 385 405 369 470 1999 54.7 154.2 74.8 156.6 137 392 529 2000 53.4 143.3 83.4 166.7 137 373 510 2001 62.8 162.8 92.3 179.1 161 433 594 2002 83.0 174.3 104.5 195.9 213 473 686 2003 88.5 190.5 111.9 199.8 227 529 756 2004 100.2 197.6 122.0 210.0 257 561 818 2005 121.2 208.6 129.6 218.4 311 604 915 2006 140.7 224.7 132.8 223.7 361 663 1,024 2007 132.1 226.3 138.1 232.6 339 680 1,019 2008 162.9 261.1 148.4 268.0 418 798 1,218 2009 170.3 271.5 163.2 295.0 437 841 1,278 2010 208.5 324.4 190.9 341.8 535 1,021 1,556 2011 224.1 356.7 207.7 371.1 575 1,138 1,714 2012 235.4 342.3 215.3 366.1 604 1,108 1,712 2013 239.3 293.3 215.7 336.3 614 963 1,577 2014 233.1 266.6 226.9 345.8 598 887 1,485 2015 263.1 313.9 249.5 371.2 675 1,056 1,731 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Chlamydia infection is frequently asymptomatic.[5] In Ontario, chlamydia is the most commonly reported sexually transmitted infection. The rate is higher among females and has been rising. Although the rates decreased between 2011 and 2013 among both Durham Region and Ontario females and a levelled off among Durham Region males, rates increased again between 2014 and 2015. More detailed information on chlamydia in Durham Region is available in the Snapshot on Chlamydia, 2011 available at www.durham.ca/healthstats. Page 25 of 47 Figure 19: Chlamydia Age-Specific Incidence Rates, Durham Region and Ontario, 2011-2015 Combined Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 10-14 15-19 20-24 0.0 353.5 1020.7 20.2 1192.5 1880.9 2.5 368.2 1013.3 25.7 1313.9 1862.9 0 427 1,206 20 1,366 2,125 20 1,793 3,331 25-29 691.0 786.3 709.4 857.6 684 775 1,460 30-39 233.3 276.3 292.3 324.1 461 590 1,051 40-49 82.1 83.5 103.7 95.3 197 210 407 50-59 28.8 20.9 35.5 29.8 71 52 123 60+ 7.0 3.7 7.2 3.7 19 12 31 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department, April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. The rate of chlamydia is higher among females in most age groups. Reported rates are highest among youth and young adults aged 15 to 29 years. Rates among those less than 10 years of age are excluded due to small counts. Page 26 of 47 Figure 20: Chlamydia Incidence Rates in Youth 15-19 Years of Age, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 243.1 1202 183.1 1148 37 172 209 1994 218.3 1116 155.9 1053 34 163 197 1995 132.4 762.5 132.5 931.3 21 114 135 1996 110.3 983.1 109.3 790.6 18 151 169 1997 101.4 794.4 111.2 762.4 17 126 143 1998 103.3 978.4 146.8 864.4 18 162 180 1999 206.1 1106 154.5 849.1 37 192 229 2000 174.3 928.6 184.9 916.1 33 169 202 2001 131.8 957.3 192.3 963.9 26 181 207 2002 201.4 1034 205.4 1023 41 200 241 2003 167.5 1006 219.3 1055 35 199 234 2004 170.7 978.2 234.0 1055 37 200 237 2005 245.4 1152 241.4 1073 55 246 301 2006 309.7 1282 228.5 1036 72 286 358 2007 264.8 1172 245.8 1032 63 268 331 2008 300.2 1323 272.8 1171 73 311 385 2009 357.3 1313 319.2 1259 88 313 401 2010 370.8 1468 352.5 1425 92 350 442 2011 357.0 1516 370.7 1477 89 361 450 2012 359.9 1229 378.6 1372 89 288 377 2013 313.6 1052 345.3 1219 76 241 317 2014 366.9 999 361.9 1223 87 224 311 2015 371.1 1147 384.6 1269 86 252 338 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Chlamydia infection is frequently asymptomatic.[5] In Ontario, chlamydia is the most commonly reported sexually transmitted infection. The rate is higher among females ages 15 to 19 than males and increased between 1995 and 2011 in Durham Region and Ontario. Although rates decreased between 2011 and 2013 among both Durham Region and Ontario females 15 to 19 years of age and levelled off among males, rates have begun to increase again among both Durham Region and Ontario females 15 to 19 years of age since 2014. Page 27 of 47 Figure 21: Chlamydia Incidence Rates in Young Adults 20-24 Years of Age, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 276.0 1055 370.2 1075 40 149 189 1994 290.8 825.4 338.7 1048 42 115 157 1995 304.1 890.9 289.2 930.9 44 124 168 1996 186.9 738.0 258.3 824.2 27 101 128 1997 268.1 797.3 270.3 780.7 40 112 152 1998 420.7 908.7 355.6 851.5 64 129 193 1999 286.4 939.5 388.9 924.8 45 136 181 2000 329.4 860.6 427.4 944.9 53 128 181 2001 366.0 1152 484.7 1047 61 179 240 2002 485.3 1034 554.0 1147 84 168 252 2003 480.7 1169 602.5 1169 87 199 286 2004 610.0 1261 672.0 1232 113 223 336 2005 657.2 1291 671.7 1278 127 235 362 2006 777.7 1396 684.7 1311 155 260 415 2007 669.6 1355 707.2 1326 136 260 396 2008 749.3 1408 753.7 1488 153 274 428 2009 841.1 1513 834.1 1573 175 300 475 2010 1061 1877 965.3 1826 226 384 610 2011 1009 2095 1028 1953 221 442 663 2012 1063 2095 996.1 1927 245 460 705 2013 1016 1761 975.8 1748 244 403 647 2014 970.6 1567 989.4 1750 239 368 607 2015 1047 1919 1077 1942 257 452 709 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Chlamydia infection is frequently asymptomatic.[5] In Ontario, chlamydia is the most commonly reported sexually transmitted infection. The rate is higher among females ages 20 to 24 than males and increased between 1997 and 2011 in Durham Region and Ontario. Although rates decreased between 2011 and 2013 among both Durham Region and Ontario females age 20 to 24 and levelled off among males, rates have begun to increase again among both Durham Region and Ontario males and females 20 to 24 years of age since 2014. Page 28 of 47 Figure 22: Chlamydia Incidence Rates in Young Adults 25-29 Years of Age, Durham Region and Ontario, 1993-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 1993 78.1 199.4 169.4 340.5 14 37 51 1994 125.1 195.3 160.2 341.6 21 34 55 1995 81.6 199.3 150.2 311.0 13 33 46 1996 137.6 279.9 145.4 285.9 21 45 66 1997 73.1 198.9 145.6 286.6 11 31 42 1998 131.4 205.8 205.3 316.8 20 32 52 1999 169.8 219.8 228.8 336.2 26 34 60 2000 185.6 262.9 245.1 370.9 29 41 70 2001 258.6 278.4 293.7 394.2 41 43 84 2002 251.9 338.4 334.2 435.2 40 53 93 2003 346.5 494.5 371.2 442.9 56 79 135 2004 318.4 433.0 384.2 462.5 53 71 124 2005 410.1 388.5 431.9 498.9 69 65 134 2006 334.0 382.1 426.3 507.0 57 65 122 2007 431.4 514.7 462.9 557.5 75 90 165 2008 516.8 560.4 477.4 632.5 91 101 192 2009 440.6 564.1 518.8 705.8 78 104 182 2010 562.9 688.5 601.4 789.2 103 129 232 2011 685.8 824.1 661.6 862.6 128 156 285 2012 671.6 862.5 686.7 855.3 129 166 295 2013 736.5 827.0 693.6 810.8 145 162 307 2014 648.5 712.9 716.0 853.7 133 144 277 2015 712.2 713.6 786.1 904.1 149 147 296 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Chlamydia infection is frequently asymptomatic.[5] In Ontario, chlamydia is the most commonly reported sexually transmitted infection. The rate is higher among females ages 25 to 29 than males and increased between 1997 and 2011 in Durham Region and Ontario. Although rates decreased between 2012 and 2014 in Durham Region females and between 2013 and 2014 in Durham Region males, rates have levelled off among Durham Region females and begun to increase again among Durham Region males 25 to 29 years of age. Page 29 of 47 Figure 23: Chlamydia Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 219.4 252.4 158.2 220.5 152.7 102.2 199.2 2009 208.4 265.1 204.3 242.7 124.3 82.0 205.5 2010 331.7 284.5 203.0 261.1 172.7 160.7 248.5 2011 326.9 337.4 227.5 305.6 180.6 123.6 270.7 2012 277.8 355.0 237.6 320.6 171.1 145.3 267.6 2013 248.6 286.0 212.7 305.1 171.4 158.1 243.7 2014 246.8 275.7 192.2 276.4 160.6 147.5 227.8 2015 294.1 297.9 209.0 314.0 213.7 198.1 263.0 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Chlamydia infection is frequently asymptomatic.[5] In Ontario, chlamydia is the most commonly reported sexually transmitted infection. The rate of chlamydia is higher most years in Pickering, Ajax, and Oshawa than Durham Region as a whole, and lower in Whitby, Clarington, and the northern municipalities (Brock, Scugog and Uxbridge combined). Page 30 of 47 Figure 24: Gonorrhea Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 Durham Male Rate 18.9 19.9 Durham Female Rate 21.5 26.3 Ontario Male Rate 31.9 35.2 Ontario Female Rate 24.6 25.4 Durham Male Cases 42 45 Durham Female Cases 48 60 Durham Total Cases 90 105 1995 16.0 18.9 31.7 22.8 37 44 81 1996 13.2 15.6 23.9 18.0 31 37 68 1997 12.1 12.7 20.5 13.5 29 31 60 1998 14.6 15.7 24.0 15.6 36 39 75 1999 15.6 16.1 23.5 15.9 39 41 80 2000 14.0 16.1 29.4 19.3 36 42 78 2001 15.2 16.9 30.5 19.0 39 45 84 2002 12.9 19.5 31.4 19.4 33 53 86 2003 20.3 17.3 33.7 21.0 52 48 100 2004 18.3 16.2 34.7 21.8 47 46 93 2005 21.8 20.0 33.6 19.6 56 58 114 2006 30.8 23.7 39.2 22.3 79 70 149 2007 39.4 23.6 37.8 25.5 101 71 172 2008 36.3 31.1 36.1 25.7 93 95 189 2009 24.9 27.4 32.0 24.7 64 85 149 2010 29.2 24.8 35.5 27.9 75 78 153 2011 32.7 26.6 38.8 28.4 84 85 170 2012 26.5 27.5 38.6 26.9 68 89 157 2013 32.7 22.2 46.1 26.5 84 73 157 2014 44.0 29.8 61.6 31.9 113 99 212 2015 47.9 34.8 63.7 31.3 123 117 240 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Like chlamydia, gonorrhea infections are frequently asymptomatic.[5] In Ontario, gonorrhea is a commonly reported sexually transmitted infection. In Ontario and Durham Region rates of gonorrhea are higher among males compared to females. Rates of gonorrhea increased in both Durham Region and Ontario from 1997 to 2006, remained relatively stable between 2006 and 2009 and have been increasing again since 2009, especially among males. Page 31 of 47 Figure 25: Gonorrhea Age-Specific Incidence Rates, Durham Region and Ontario, 2011-2015 Combined Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 15-19 31.5 127.5 45.6 106.7 38 146 184 20-24 134.6 131.0 151.5 130.8 159 148 308 25-29 86.9 74.1 150.9 71.5 86 73 159 30-39 48.6 30.0 89.9 29.6 96 64 160 40-49 26.2 8.3 44.7 10.5 63 21 84 50+ 5.6 1.4 10.2 1.9 29 8 37 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department, April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Reported rates of gonorrhea are highest among young adults ages 20 to 24 years and among females ages 15 to 19 years in both Durham Region and Ontario and also among Ontario males ages 25 to 29. Rates are higher in Ontario males than Durham Region males for all age groups. Rates are similar in Ontario and Durham Region females with the exception of Durham Region females ages 15 to 19 who have higher rates than Ontario females 15 to 19. Rates among those ages 14 years and younger are excluded due to small counts. Page 32 of 47 Figure 26: Gonorrhea Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 33.7 34.0 26.4 46.7 11.8 5.4 30.9 2009 23.8 36.7 18.5 31.9 9.3 12.5 24.0 2010 37.8 40.6 16.7 25.3 6.9 5.4 24.4 2011 36.8 27.2 22.0 33.4 13.6 12.5 26.9 2012 30.1 35.5 17.8 33.8 10.1 5.4 24.5 2013 25.5 33.1 19.9 31.7 13.2 9.0 24.3 2014 40.3 33.5 21.3 50.4 21.7 10.8 32.5 2015 40.1 46.1 26.4 48.1 29.9 10.8 36.5 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Like chlamydia, gonorrhea infections are frequently asymptomatic.[5] In Ontario, gonorrhea is a commonly reported sexually transmitted infection. The rate of gonorrhea is higher most years in Pickering, Ajax, and Oshawa than Durham Region as a whole, and lower in Whitby, Clarington and the northern municipalities (Brock, Scugog and Uxbridge combined). Page 33 of 47 Figure 27: Syphilis Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 2.5 1.3 1.7 1.5 1.2 1.2 1.4 1.7 1.9 3.5 1.5 1.2 4.9 12.8 7.6 6.8 9.0 9.2 7.7 7.5 6.2 4.4 6.1 Ontario Rate 5.7 3.9 3.4 2.8 2.3 2.2 2.5 2.6 2.5 4.6 5.4 6.2 9.8 17.7 14.5 12.9 14.1 12.6 12.2 12.5 10.6 11.9 13.2 Durham Male Cases 2 1 1 2 1 1 0 2 3 4 2 3 2 4 4 5 12 21 13 20 14 12 17 Durham Female Cases 9 5 7 5 5 5 7 7 7 15 6 4 26 71 41 36 43 36 35 28 26 17 23 Durham Total Cases 11 6 8 7 6 6 7 9 10 19 8 7 28 75 45 41 55 57 48 48 40 29 40 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Syphilis is a serious sexually transmitted bacterial infection. The early stages of syphilis, primary, secondary, and early latent are considered infectious. [5] The rate of syphilis had been going down in Ontario until 2001 when it began to increase again, especially among the population of men who have sex with men (MSM). Although rates decreased again between 2006 and 2013 in both Durham Region and Ontario, rates have increased since 2013 in Ontario and 2014 in Durham Region. Due to small numbers, male and female cases are combined to create more stable rates. Page 34 of 47 Figure 28: Chronic Hepatitis B Incidence Rates, Durham Region and Ontario, 1993-2015 Rates and Cases 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Durham Rate 16.9 15.8 10.8 12.5 4.1 5.5 1.6 7.2 9.1 10.6 9.6 13.0 11.9 7.4 7.6 8.5 7.4 5.7 5.4 5.3 6.0 5.4 4.5 Ontario Rate 63.3 54.1 51.3 44.0 34.9 33.9 35.6 36.7 39.2 41.5 36.9 40.0 36.1 32.1 30.0 26.2 25.6 23.3 23.2 20.1 19.6 18.7 15.8 Durham Male Cases 41 32 25 28 8 17 6 25 32 35 35 39 39 26 28 31 31 16 27 17 22 23 16 Durham Female Cases 34 40 25 31 12 10 2 12 16 22 18 34 28 17 17 20 14 19 7 17 17 12 13 Durham Total Cases 75 72 50 59 20 27 8 37 48 57 53 73 68 43 45 51 45 35 34 34 39 35 30 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 1993-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (1993-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Hepatitis is a disease of the liver most commonly caused by a virus. The hepatitis B virus can initially cause an acute infection which may not cause symptoms. If the virus remains in the blood for more than six months it is considered a chronic infection.[8] Rates of infection are decreasing over time for both Durham Region and Ontario. Due to small numbers, male and female cases are combined to create more stable rates. Page 35 of 47 Figure 29: Hepatitis C Incidence Rates, Durham Region and Ontario, 2003-2015 Rates and Cases Durham Male Rate Durham Female Rate Ontario Male Rate Ontario Female Rate Durham Male Cases Durham Female Cases Durham Total Cases 2003 50.7 28.5 56.6 31.3 130 79 209 2004 57.3 28.5 56.4 29.4 147 81 229 2005 56.9 28.7 47.7 25.4 146 83 229 2006 48.3 22.0 41.5 23.0 124 65 190 2007 36.6 25.6 45.2 28.8 94 77 171 2008 45.2 28.5 45.5 29.8 116 87 203 2009 42.1 21.3 45.7 28.2 108 66 174 2010 40.5 22.9 45.6 26.7 104 72 177 2011 44.0 19.4 41.1 25.6 113 62 177 2012 40.5 19.5 40.6 26.4 104 63 167 2013 40.5 21.3 42.5 24.7 104 70 174 2014 41.3 19.2 42.6 25.1 106 64 170 2015 40.1 17.8 42.4 25.4 103 60 163 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2003-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2003-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2003-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Hepatitis is a disease of the liver most commonly caused by a virus. Hepatitis C is primarily transmitted by blood-to-blood contact.[5] In Ontario hepatitis C is reported more for prevalence than incidence. Most cases are reported some months/years following infection so higher or lower rates can be misleading. Cases of hepatitis C are seen more often among men compared to women. Data prior to 2003 are excluded due to inconsistent reporting. Rates of hepatitis C have remained relatively stable in both Durham Region and Ontario since 2007 and are higher among males than females. Page 36 of 47 Figure 30: Hepatitis C Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 29.3 13.2 25.5 54.0 10.7 30.5 33.2 2009 14.0 15.6 15.3 52.7 20.9 21.4 28.0 2010 11.9 23.5 19.1 57.0 15.0 23.2 28.3 2011 13.0 17.5 21.3 58.4 22.7 12.5 28.0 2012 17.2 12.1 20.1 52.3 20.1 17.9 26.1 2013 18.1 17.8 13.8 57.7 17.6 19.8 26.9 2014 10.6 14.2 16.7 54.2 23.9 19.8 25.8 2015 14.8 12.3 17.4 52.4 19.2 16.2 24.8 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. Hepatitis is a disease of the liver most commonly caused by a virus. Hepatitis C is primarily transmitted by blood-to-blood contact.[5] In Ontario hepatitis C is reported more for prevalence than incidence. Most cases are reported some months/years following infection so higher or lower rates can be misleading. The rate of hepatitis C infection is consistently higher in Oshawa than in other Durham Region municipalities, and higher than in Durham Region as a whole. Page 37 of 47 Tuberculosis Tuberculosis (TB) presents itself in two different forms: active TB disease and latent tuberculosis infection (LTBI). The majority of individuals infected have LTBI and about 10% will eventually develop active disease.[9] Appropriate completion of treatment for LTBI can considerably reduce the lifetime risk of developing active TB disease. Page 38 of 47 Figure 31: Latent Tuberculosis Infection Incidence Rates, Durham Region and Ontario, 2006-2015 Rates and Cases 2006 2007 2008 2009 2010 2011 2012 2013 Durham Male Rate 23.7 28.3 35.0 28.4 24.8 17.2 26.3 18.9 Durham Female Rate 50.2 44.9 53.3 43.3 48.9 40.4 42.3 41.4 Ontario Male Rate 63.3 71.7 79.2 74.2 75.1 74.9 61.3 55.7 Ontario Female Rate 80.1 86.5 84.3 77.8 75.3 76.7 73.6 71.5 Durham Male Cases 70 85 107 88 78 55 85 62 Durham Female Cases 148 135 163 134 154 129 137 136 Durham Total Cases 218 220 270 222 234 186 222 198 2014 26.2 52.3 48.2 72.9 87 174 263 2015 24.4 59.4 44.1 67.7 82 200 283 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2006-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2006-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2006-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. Latent tuberculosis infection (LTBI) rates have remained fairly stable in both Durham Region and Ontario although rates have decreased among Ontario males since 2011. LTBI rates are consistently higher among Durham Region females than males and have been increasing since 2013 but remain lower than Ontario rates. Page 39 of 47 Figure 32: Latent Tuberculosis Infection Incidence Rates, Durham Region by Municipality, 2008-2015 Rates by Municipality Pickering Ajax Whitby Oshawa Clarington North Durham Durham Region 2008 44.5 61.5 34.6 39.5 22.5 17.9 44.2 2009 37.8 62.4 27.4 33.8 13.9 5.3 35.7 2010 32.4 46.1 44.6 38.2 16.1 16.1 37.4 2011 39.0 34.2 26.0 29.5 14.8 16.1 29.4 2012 31.2 54.5 38.7 33.1 19.0 17.9 34.7 2013 38.2 45.0 32.9 31.1 13.2 7.2 30.6 2014 27.5 75.4 38.0 49.7 11.9 9.0 40.3 2015 47.4 76.5 39.2 46.8 13.9 9.0 43.0 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2008-2015, extracted by Durham Region Health Department April 2016; and Population Estimates, Durham Region Planning & Economic Development Committee, Commissioner’s Report 2013-P-23, February 19, 2013 and Commissioner’s Report 2015-P-55, September 9, 2015. The rate of latent tuberculosis infection is consistently higher in Ajax than in Durham Region as a whole, while rates are lower in Clarington and the northern municipalities (Brock, Scugog and Uxbridge combined). Pickering, Whitby and Oshawa have rates similar to Durham Region as a whole. Page 40 of 47 Age Standardized Incidence Ratios for Selected Reportable Diseases An age standardized incidence ratio (SIR) is the ratio of the number of cases observed in the population of interest to the number of cases that would be expected if the population had the same age-specific incidence rates as a standard population. Ontario is used here as the standard population. Since statistical estimates may be unstable when the number of events is small, confidence intervals (CIs) are used to determine whether an SIR is statistically different from 1. 95% CIs are represented in the following graphs by upright bars. If these bars cross 1 this means that the Durham incidence rate is no different from Ontario. An SIR and CIs greater than 1 indicate that the incidence rate is higher in Durham than Ontario, whereas an SIR and CIs less than 1 indicate that incidence is lower in Durham. Page 41 of 47 Figure 33: Age-Standardized Incidence Ratios for Selected Reportable Diseases, Durham Region Males, 2011-2015 Combined SIR and Confidence Intervals SIR Lower Confidence Interval Upper Confidence Interval Enteric Disease Campylobacter All STIs * & Salmonellosis Giardiasis Enteritis Bloodborne Chlamydia Gonorrhea Chronic Hepatitis B Hepatitis C VDPs * Minus Influenza Influenza Pertussis LTBI * IPD * 0.85 0.97 1.01 0.77 0.84 0.93 0.65 0.40 0.87 0.79 0.64 0.41 0.42 0.99 0.80 0.89 0.90 0.65 0.82 0.90 0.59 0.32 0.80 0.68 0.59 0.24 0.37 0.83 0.90 1.06 1.12 0.90 0.87 0.97 0.71 0.48 0.95 0.90 0.70 0.57 0.46 1.16 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. * STI = Sexually Transmitted Infection; VPD = Vaccine Preventable Disease; LTBI = Latent Tuberculosis Infection; IPD = Invasive Pneumococcal Disease Durham Region males had significantly lower incidence rates for all enteric diseases, giardiasis, all STIs and bloodborne diseases, chlamydia, gonorrhea, hepatitis B carriers, hepatitis C, all VPDs (excluding influenza), influenza, pertussis, and latent tuberculosis infection as compared to Ontario. Incidence rates were similar in Durham Region and Ontario males for Campylobacter enteritis, salmonellosis, and IPD. Page 42 of 47 Figure 34: Age-Standardized Incidence Ratios for Selected Reportable Diseases, Durham Region Females, 2011-2015 Combined SIR and Confidence Intervals SIR Lower Confidence Interval Upper Confidence Interval Enteric Disease Campylobacter All STIs * & Salmonellosis Giardiasis Enteritis Bloodborne Chlamydia Gonorrhea Chronic Hepatitis B Hepatitis C VDPs * Minus Influenza Influenza Pertussis LTBI * IPD * 0.92 0.96 1.09 0.80 0.93 0.94 1.04 0.31 0.84 0.77 0.62 0.53 0.65 0.96 0.87 0.86 0.98 0.64 0.91 0.91 0.94 0.24 0.75 0.65 0.57 0.36 0.61 0.78 0.98 1.05 1.20 0.96 0.96 0.96 1.13 0.39 0.93 0.89 0.67 0.70 0.70 1.13 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. * STI = Sexually Transmitted Infection; VPD = Vaccine Preventable Disease; LTBI = Latent Tuberculosis Infection; IPD = Invasive Pneumococcal Disease Durham Region females had significantly lower incidence rates for all enteric diseases, giardiasis, all STIs and bloodborne diseases, chlamydia, hepatitis B carriers, hepatitis C, all VPDs (excluding influenza), influenza, pertussis, and latent tuberculosis infection as compared to Ontario. Incidence rates were similar in Durham Region and Ontario females for Campylobacter enteritis, salmonellosis, gonorrhea, and IPD. Page 43 of 47 Figure 35: Age-Standardized Incidence Ratios for Selected Reportable Diseases, Durham Region, 2011-2015 Combined SIR and Confidence Intervals SIR Lower Confidence Interval Upper Confidence Interval Infectious Syphilis NonInfectious Syphilis Hepatitis A VTEC * Yersiniosis Amebiasis Shigellosis IMD * Group A Streptococcus, Invasive TB * 0.37 0.85 0.54 0.83 0.69 0.56 1.04 0.48 0.39 1.31 0.68 0.42 0.29 0.70 0.25 0.57 0.45 0.40 0.70 0.38 0.24 0.50 0.55 0.32 0.46 0.99 0.84 1.10 0.93 0.72 1.39 0.58 0.54 2.12 0.81 0.53 Cryptosporidiosis Cyclosporiasis Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 2011-2015, extracted by Durham Region Health Department April 2016; iPHIS, Ontario, 2011-2015, Public Health Ontario, Accessed April 2016; and Ontario Population Estimates/Projections (2011-2015), Ontario Ministry of Health and Long-Term Care, Accessed April 2016. * VTEC = Verotoxin-producing Escherichia coli; IMD = Invasive Meningococcal Disease; TB = Tuberculosis Durham Region residents had significantly lower incidence rates for infectious syphilis, non-infectious syphilis, hepatitis A, yersiniosis, cryptosporidiosis, amebiasis, shigellosis, invasive group A streptococcus and TB as compared to Ontario. Incidence rates were similar in Durham Region and Ontario for verotoxin-producing Escherichia coli, cyclosporiasis and invasive meningococcal disease. Page 44 of 47 Number of Confirmed Cases of Selected Reportable Diseases in Durham Region Reportable Disease 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Acute Flaccid Paralysis ---------------------1 0 Adverse Events Following -------------12 40 27 85 41 54 48 64 77 80 Immunization (AEFIs) Amebiasis * 4 8 8 9 3 7 3 6 1 13 13 20 7 6 10 10 13 21 15 13 19 24 19 Botulism * 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 Brucellosis * 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 1 Campylobacter enteritis * 269 307 310 209 205 200 136 171 219 174 165 167 140 155 155 156 146 127 143 184 195 192 129 Chlamydia trachomatis 499 463 385 405 369 470 529 510 594 686 756 818 915 1,024 1,019 1,218 1,278 1,556 1,714 1,712 1,577 1,485 1,731 infections Cholera 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 Creutzfeldt-Jakob Disease, all 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 2 0 0 types Cryptosporidiosis * 0 0 0 2 5 6 10 5 4 6 12 6 10 15 12 8 4 10 8 9 6 10 14 Cyclosporiasis * 0 0 0 0 0 0 0 0 0 1 0 6 6 2 1 5 3 4 9 5 5 6 10 Encephalitis – Primary, viral * 5 13 4 6 9 8 6 4 7 1 11 7 1 0 0 0 0 0 0 1 2 0 1 Encephalitis – Unspecified * 0 2 1 4 2 4 4 4 2 1 2 1 0 0 1 0 0 0 0 1 0 0 0 Encephalitis/Meningitis * 1 1 1 1 0 5 4 4 11 5 8 8 7 7 12 7 4 11 12 0 0 0 0 Food poisoning, all causes * 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 1 6 18 4 8 0 1 Giardiasis * 113 98 72 89 91 55 49 35 34 60 49 56 39 62 46 58 54 38 39 55 51 55 53 Gonorrhoea 90 105 81 68 60 75 80 78 84 86 100 93 114 149 172 189 149 153 170 157 157 212 240 Group A Streptococcal Disease, 1 0 3 10 10 11 7 9 11 20 27 11 18 11 15 18 10 19 23 15 19 25 18 invasive (iGAS) Group B Streptococcal disease, 0 0 0 4 4 2 2 2 3 4 4 2 1 3 0 2 1 2 4 1 6 1 3 neonatal Haemophilus influenzae type b 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 disease, invasive Hemorrhagic fevers - other viral 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 causes Hepatitis A * 4 3 10 16 7 13 3 6 0 7 9 4 3 5 2 2 3 6 3 4 3 2 1 Hepatitis B - acute cases 8 2 10 6 2 0 0 1 0 2 1 1 0 5 5 1 0 0 0 1 1 6 2 Hepatitis B - carriers 75 72 50 59 20 27 8 37 48 57 53 73 68 43 45 51 45 35 34 34 39 35 30 Hepatitis C ----------- 209 229 229 190 171 203 174 177 177 167 174 170 163 HIV/AIDS 31 29 15 16 9 15 8 10 7 10 10 14 9 13 12 17 8 10 7 12 16 15 16 Influenza 26 8 22 54 24 132 125 34 45 92 179 26 176 91 101 147 536 72 90 204 230 450 225 Legionellosis * 2 2 0 4 3 5 4 0 2 1 7 1 3 5 2 5 3 8 14 12 21 8 12 Leprosy 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 Listeriosis 3 0 3 0 0 1 0 1 0 0 1 2 1 0 1 0 1 0 4 2 2 1 3 Page 45 of 47 Reportable Disease Lyme Disease * Malaria Measles * Meningitis - bacterial Meningitis - other Meningitis - viral Meningococcal disease, invasive * Mumps * Paratyphoid Fever Pertussis (Whooping Cough) * Q Fever Rubella * Salmonellosis * Shigellosis * Streptococcus pneumoniae, invasive * Syphilis, infectious Syphilis, non-infectious Tuberculosis - active cases Tuberculosis - latent TB infection (LTBI) Tuberculosis - medical surveillance cases Tularemia * Typhoid Fever Verotoxin producing E. coli including Haemolytic Uraemic Syndrome (HUS) * West Nile Virus Illness * Yersiniosis * 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 1 2 18 3 0 0 1 1 11 2 0 0 0 5 12 5 0 0 1 2 3 8 0 0 1 0 1 4 0 0 0 2 0 1 0 0 1 0 0 4 0 0 0 3 2 3 0 0 0 1 0 3 0 0 0 2 0 2 0 0 0 0 0 0 0 0 1 2 0 2 0 0 0 4 0 0 0 0 1 3 0 0 0 3 6 1 0 0 0 0 0 3 2 0 0 0 1 0 0 0 0 0 4 6 0 0 0 0 1 4 0 0 0 0 3 8 1 1 0 16 12 12 0 3 0 10 14 8 0 4 0 6 17 6 0 0 1 11 2 6 3 8 2 4 2 0 6 3 1 1 1 2 4 2 5 3 1 3 1 2 3 8 1 25 0 7 100 15 7 0 98 0 7 100 10 9 1 92 1 3 93 13 2 0 93 2 1 94 5 5 0 88 0 1 82 14 1 0 83 0 0 97 9 3 0 56 0 0 39 3 1 0 27 0 0 88 7 3 0 28 0 0 104 4 1 0 11 0 0 122 45 0 1 24 1 0 91 9 1 0 48 0 0 87 6 0 1 41 1 0 118 6 0 0 53 0 0 111 6 0 0 51 1 0 153 12 0 1 33 0 0 111 3 2 0 8 1 0 114 8 1 0 0 0 0 138 6 7 1 4 1 0 137 7 1 1 20 3 0 150 4 0 1 7 1 0 138 6 0 0 13 5 0 141 6 0 2 17 4 0 154 3 -- -- -- -- -- -- -- -- -- -- 40 47 44 24 46 43 51 56 56 57 45 48 43 2 9 3 1 5 8 1 7 12 2 5 10 1 5 8 1 5 15 0 7 14 2 7 9 3 7 18 4 15 9 2 6 11 3 4 11 2 26 6 4 71 7 4 41 14 5 36 15 12 43 12 21 36 9 13 35 15 20 28 7 14 26 9 12 17 12 17 23 17 -- -- -- -- -- -- -- -- -- -- -- 249 246 218 220 270 222 234 186 222 198 263 283 17 24 11 22 42 37 33 40 48 49 62 54 58 59 64 50 50 55 59 49 48 51 59 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 2 1 0 0 0 0 1 0 0 0 2 0 5 0 0 0 0 0 3 0 3 0 3 0 3 0 0 18 14 26 18 14 11 4 19 13 11 7 8 18 12 13 9 8 11 8 8 13 1 8 0 15 0 19 0 25 0 16 0 11 0 9 0 3 0 8 0 8 2 8 0 8 0 8 0 8 0 14 1 7 1 3 0 7 1 5 2 4 8 6 3 6 0 5 2 10 Data Source: Ontario Ministry of Health and Long-Term Care, integrated Public Health Information System (iPHIS) database, 1993-2015, extracted by Durham Region Health Department, April 2016. * Probable cases included along with confirmed cases for these diseases from 2009 onward to enable comparison to previous years as a result of changes to case definitions in 2009. -- indicates data not available Reportable diseases with no cases reported in Durham Region since 1993 include: chancroid; diptheria; Ebola virus disease; hantavirus pulmonary syndrome; Lassa Fever; Marburg virus disease; paralytic shellfish poisoning; plague; poliomyelitis, acute; psittacosis/ornithosis; rabies (human); rubella, congenital syndrome; Severe Acute Respiratory Syndrome (SARS); smallpox; tetanus; trichinosis; and yellow fever. Page 46 of 47 References 1. Health Protection and Promotion Act, RSO 1990, c H7. Available from: http://www.e-laws.gov.on.ca/html/statutes/english/elaws_statutes_90h07_e.htm 2. Ontario Ministry of Health and Long-Term Care. Infectious Diseases Protocol, 2015. Toronto, ON: Queen’s Printer for Ontario, 2015. Retrieved May 10, 2016. Available from: http://www.health.gov.on.ca/en/pro/programs/publichealth/oph_standards/infdispro.aspx 3. Ontario Ministry of Health and Long-Term Care. Infectious Diseases Protocol, 2015. Appendix B: Provincial Case Definitions. Toronto, ON: Queen’s Printer for Ontario, 2015. Retrieved May 10, 2016. Available from: http://www.health.gov.on.ca/en/pro/programs/publichealth/oph_standards/infdispro.aspx 4. Ontario Ministry of Health and Long-Term Care. Ontario Public Health Standards 2008. Toronto, ON: Queen’s Printer for Ontario, 2015. Retrieved May 10, 2016. Available from: http://www.health.gov.on.ca/en/pro/programs/publichealth/oph_standards/default.aspx 5. Ontario Ministry of Health and Long-Term Care. Infectious Diseases Protocol, 2015. Appendix A: Disease-Specific Chapters. Toronto, ON: Queen’s Printer for Ontario, 2015. Retrieved May 10, 2016. Available from: http://www.health.gov.on.ca/en/pro/programs/publichealth/oph_standards/infdispro.aspx 6. Public Health Ontario. Immunization coverage report for school pupils: 2010/11 school year. Toronto, ON: Public Health Ontario, 2012. 7. Toronto Public Health. Communicable Diseases in Toronto 2014. City of Toronto: Toronto, Canada. February 2016. Retrieved May 10, 2016. Available from : http://www1.toronto.ca/wps/portal/contentonly?vgnextoid=1c952d6855e02410VgnVCM10000071d60f89RCRD 8. Shepard, C. W., Simard, E. P., Finelli, L., Fiore, A. E., & Bell, B. P. (2006). Hepatitis B virus infection: Epidemiology and vaccination. Epidemiologic Reviews, 28(1), 112-125. 9. Durham Region Health Department. Snapshot on Tuberculosis. October 2011. Retrieved July 18, 2013. Available from: http://www.durham.ca/departments/health/health_statistics/snapshot/tbOct2011.pdf Page 47 of 47