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CHEMICAL BARRIERS:
Transferrin

Transferrin binds iron.

It competitively inhibits the growth of
pathogens.
Microbiology: A Clinical Approach
Approach, ©
byGarland
Tony Srelkauskas
Science © Garland Science
ISBN: 978-0-8153-6514-3
SECOND LINE OF DEFENSE:
Cellular and Chemical Responses

One cellular response:


Phagocytosis
Several chemical responses:

Inflammation

Fever

The complement system

Interferon
Microbiology: A Clinical Approach
Approach, ©
byGarland
Tony Srelkauskas
Science © Garland Science
ISBN: 978-0-8153-6514-3
TOLL-LIKE RECEPTORS

Toll-like receptors (TLRs) are used to
differentiate between self and nonself antigens.

Located on the surface of host defense cells

Bind to antigens found on pathogens
Microbiology: A Clinical Approach
Approach, ©
byGarland
Tony Srelkauskas
Science © Garland Science
ISBN: 978-0-8153-6514-3
Microbiology: A Clinical Approach [9780815365143] © Garland Science