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Chapter 4 Carbohydrates: Sugars, Starches, and Fiber 4-2 • http://www.youtube.com/watch?v=dBnniua6-oM • www.sugarstacks.com Learning Objectives • Discuss the difference between refined and unrefined carbohydrates. • Compare the structure of simple and complex carbohydrates. • Distinguish between soluble and insoluble fiber and name food sources of each. • Define lactose intolerance and explain its cause. 4-3 Learning Objectives • Discuss the effects of dietary fiber on gastrointestinal function and health. • Describe the steps involved in metabolizing glucose to produce energy. • Explain how the hormones insulin and glucagon are involved in regulating blood glucose levels. 4-4 Learning Objectives • Compare the causes and consequences of type 1 and type 2 diabetes. • Discuss the health risks and benefits associated with carbohydrates. • Discuss artificial sweeteners. 4-5 What do you know already? Macronutrients: Our Main Questions • • • • • • • • • • What are they? What do they do in us? Where do they come from? Structure Digestion Metabolism and Storage Recommended Allowances Consequences of too much Consequences of too little Other Issues (substitutes, etc.) Sugars: What They Are? • White sugar (sucrose) • High-fructose corn syrup or corn syrup • Sorbitol • Brown sugar • Molasses • Honey • Powdered sugar • Raw sugar • Fiber • http://www.sugar.org/consumers/sweet_by _nature.asp?id=275 Sugars: What They Do In Us. • Carbohydrates meet your body’s energy needs – Feed your brain and nervous system – Keep your digestive system fit – Within calorie limits, help keep your body lean – Together with fats and protein, digestible carbohydrates add bulk to foods – Indigestible carbohydrates yield little or no energy but provide other benefits – DNA backbone Carbohydrates: Where do they come from? • Carbohydrate-rich foods come almost exclusively from plants – Milk is the only animalderived food that contains significant amounts of carbohydrate Carbohydrates: Where do they come from? Synthesis of Glucose and Starch 4-16 Carbohydrates (CH2O)n • Simple carbohydrates (sugars) – Monosaccharides – Disaccharides • Complex carbohydrates (polysaccharides) – Glycogen – Starch – Fiber Simple Carbohydrates • Monosaccharides – C6H12O6 • Glucose • Fructose • Galactose Simple Carbohydrates: The Monosaccharides 1. Glucose C6H12O6 • The essential energy source for all body functions. • • • Other names: Dextrose and Blood Sugar. A component of each disaccharide. The body’s main source of energy. Simple Carbohydrates: The Monosaccharides • Fructose: • The sweetest of all sugars – (1.5 X sweeter than sucrose) • Occurs naturally in fruits and honey – “the fruit sugar” Simple Carbohydrates: The Monosaccharides • Galactose – Seldom occurs freely in nature – Binds with glucose to form sugar in milk: lactose. – Once absorbed by the body, galactose is converted to glucose to provide energy. Monosaccharides to Polysaccharides • Monosaccharides can be joined to make disaccharides and polysaccharides. – Via condensation reactions • Polysaccharides can be broken down to monosaccharides. – Via hydrolysis reactions Condensation Think of clay, if you take water out, it becomes hard Hydrolysis If you put water into something, it breaks it apart Disaccharides • Maltose • Sucrose • Lactose Simple Carbohydrates: The Disaccharides Maltose Maltose = Glucose + Glucose • Produced when starch breaks down. • Used naturally in fermentation reactions of alcohol and beer manufacturing. • Aromatic in baking Simple Carbohydrates: The Disaccharides Sucrose Sucrose = Glucose + Fructose *Table sugar *Found naturally in plants: sugar cane, sugar beets, honey, maple syrup *Sucrose may be purified from plant sources into Brown, White and Powdered Sugars. Simple Carbohydrates: The Disaccharides Lactose Lactose = Glucose + Galactose • The primary sugar in milk and milk products. • Many people have problems digesting large amounts of lactose (lactose intolerance) Carbohydrates (CH2O)n • Simple carbohydrates (sugars) – Monosaccharides – Disaccharides • Complex carbohydrates (polysaccharides) – Glycogen – Starch – Fiber The Complex Carbohydrates: • Polysaccharides: containing 2 or more monosaccharides attached together Three types are important in nutrition: 1. Glycogen- digestible 2. Starch- digestible 3. Fiber- indigestible The Complex Carbohydrates: Glycogen • • • • • The storage form of glucose in the body. Stored in the liver and muscles. Found in tiny amounts in meat sources. Not found in plants. Not a significant food source of carbohydrate. The Complex Carbohydrates: Starch • The major digestible polysaccharide in our diet. • Sources: Wheat, rice, corn, rye, barley, potatoes, tubers, yams, etc. • Two types of plant starch: 1. Amylose 2. Amylopectin The Complex Carbohydrates Fiber Indigestible polysaccharides Types of fiber: 1. Soluble (dissolve in water)- gums, pectins, mucilages, some hemicellulose 2. Insoluble (do not dissolve in water)cellulose, lignin, many hemicelluloses Food Sources of Fiber • Soluble fiber 1. 2. 3. 4. Fruits Legumes Oats, barley, and rye Also seeds and vegetables • Insoluble fiber 1. Wheat bran, brown rice, whole grains 2. Vegetables (cabbage, carrots) 3. Fruits 4. Legumes Food Sources of Fiber • Soluble fiber 1. 2. 3. 4. Fruits Legumes Oats, barley, and rye Also seeds and vegetables • Insoluble fiber 1. Wheat bran, brown rice, whole grains 2. Vegetables (cabbage, carrots) 3. Fruits 4. Legumes Health Effects of Fiber • Soluble, viscous fiber – Lowers risk of heart disease & stroke by: • Binding bile – Lowers risk of diabetes and controls diabetes by: • Slowing glucose absorption – Also holds moisture in stools, softening them • Insoluble, nonviscous fiber – Alleviates constipation and lowers risk of hemorrhoids and diverticulosis by: • Increasing fecal weight and speeding fecal passage through the colon – May help with weight management Carbohydrate Digestion in the GI Tract • Simple • Starch • Fiber Simple sugars: Monosaccharides • Simple sugars are simply absorbed without digestion Carbohydrates in the Digestive Tract • Disaccharides and complex carbohydrates must be digested for monosaccharides to be absorbed. • Digestible vs. Indigestible carbohydrates 4-19 Lactose Intolerance • Not enough enzyme lactase in the small intestine to digest the milk sugar lactose • Symptoms: intestinal gas and bloating, diarrhea • More common in Asian, Native American, and Mediterranean populations • What are alternative means to meet calcium needs for lactose-tolerant populations? 4-20 Starch Fiber Indigestible Carbohydrates • Fiber, some oligosaccharides, and resistant starch • Health implications – Stimulate GI motility – Promote a healthy microflora – Slow nutrient absorption – Increase intestinal gas 4-21 Soluble Fiber—Healthy Heart • Dissolves in water or absorbs water • Can be broken down by the intestinal microflora • Includes: pectins, gums, semicelluloses • Food sources: oats, apples, beans, seaweeds • Health benefits: lower blood cholesterol 4-34 Insoluble Fiber—Happy GI Tract • Does not dissolve in water • Cannot be broken down by bacteria in the large intestine • Includes: cellulose, hemicellulose, and lignin • Food sources: wheat bran, rye bran, and vegetables • Health benefits: soften stools and decrease transit time 4-35 Indigestible Carbohydrates and the Risk of Colon Cancer • Epidemiologic studies: the incidence of colon cancer is lower in populations consuming diets high in fiber • Recent intervention studies: not supportive of the epidemiologic observations • The scientific consensus: enough evidence that diets high in fiber protect against colon cancer 4-36 Carbohydrate Metabolism • Storing glucose as glycogen • Using glucose for energy How Glucose is Stored/Used: Getting Glucose Into Cells. Constancy of Blood Glucose • Diabetes – Type 1 diabetes • Failure of insulin production – Type 2 diabetes • Obesity Abnormal Blood Glucose Levels in Diabetes Mellitus 4-28 Diabetes Mellitus: Symptoms • Immediate Symptoms – Excessive thirst, frequent urination, blurred vision, and weight loss • Long-term complications – Damage to the heart, blood vessels, kidneys, eyes, and nerves 4-29 Diabetes Mellitus: Treatment • Diet – Carbohydrate intake should be distributed through the day to control blood glucose levels, – Exchanging lists or other carbohydratecounting tools is useful • Exercise – Increase sensitivities of body cells to insulin • Medication • Insulin injection for Type 1 • Insulin can help for some Type 2 patients 4-30 Carbohydrate Metabolism • Making glucose from protein – Gluconeogenesis – Protein-sparing action of carbohydrates Carbohydrate Metabolism • Making glucose from protein – Gluconeogenesis – Protein-sparing action of carbohydrates Carbohydrate Metabolism Carbohydrate Metabolism • Converting glucose to fat – Energetically expensive • The conversion of excess glucose to fat requires many steps and costs a great deal of energy – When presented with both glucose and fat, the body prefers to store the fat and use the glucose to meet immediate energy needs • This maximizes energy storage Carbohydrate Metabolism • When presented with both glucose and fat, the body prefers to store the fat and use the glucose to meet immediate energy needs Use the glucose and store the fat Gluconeogenesis • Making glucose from protein 4-23 Carbohydrates are Needed to Break Down Fat 4-24 Constancy of Blood Glucose • Hypoglycemia – Rare in healthy people http://en.wikipedia.org/wiki /Hypoglycemia Hypoglycemia: Low Blood Glucose • Can occur in people with diabetes as a result of over-medication or imbalance between insulin level and carbohydrate intake • Can result from abnormalities in the production or response to insulin or other hormones involved in blood sugar regulation – Reactive and fasting 4-31 Constancy of Blood Glucose • Glycemic response – Glycemic index • A measure of how fast sugar is digested https://www.diabetesnet.com/diabetes_food_ diet/glycemic_index.php http://www.mendosa.com/gilists.htm Glycemic Response • The rate, magnitude, and duration of the rise in blood glucose that occurs after a food or meal is consumed. – Glycemic index: a ranking of how a food affects blood glucose compared to the response of a reference food – Glycemic load: an index of glycemic response 4-25 Accusations Against Sugars • Sugar causes obesity • Sugar causes heart disease Accusations Against Sugars • Sugar causes misbehavior in children and criminal behavior in adults Accusations Against Sugars • Sugar causes cravings and addictions – serotonin Carbohydrate Recommendations • The RDA: – Minimum amount required to provide adequate glucose for the brain – Set at 130 g/day (~ 420 kcalories) • The Range of Healthy Intakes: – Set at 45% to 65% of energy – No more than 25% of energy should come from added refined sugars • An AI for Fiber: – Set at 38g/day for young adult men and 25g/day for young adult women 4-37 Carbohydrate Content of Selections from Each Food Group of MyPyramid 4-38 Calculating Percentage Energy from Carbohydrate 4-39 Carbohydrates on Food Labels • Grams of total carbohydrate, fiber, and sugars listed • Amounts of soluble and insoluble fiber not required • Total carbohydrate and fiber also listed as a percent of the Daily Value 4-41 Looking for Sugars and Fibers on the Food Labels 4-42 Looking for Sugars and Fibers on the Food Labels 4-43 Translating Recommendations into Healthy Diets 4-44 Alternatives to Sugar • Artificial sweeteners vs. sugar replacers (nutritive sweeteners) Alternative Sweeteners • Acceptable Daily Intakes (ADIs) set by FDA • Cut down on kcalories in, but do not add whole grains, fruits, and vegetables to the diet • Have been shown to reduce the incidence of dental caries • Usefulness for weight loss controversial 4-45 • Types of Alternative Sweeteners Saccharin – 200–700 times sweeter than sugar – No warning labels required since May 2000 • Aspartame – Made of aspartic acid and phenylalanine – Can be dangerous to people with phenylketonuria (PKU) • Sucralose (Trichlorogalactosucrose) – Sold under the name “Splenda” – Derived from sugar 4-46 • Types of Alternative Acesulfame Sweeteners K – 200 times as sweet as sugar – Heat stable • Neotame – Similar to aspartame, with stronger chemical bond (cannot be broken down easily) – 7000–13,000 times sweeter than sugar! • Sugar alcohols – Chemical derivatives of sugar – Low-calorie: 0.2–3 kcalories/gram – Can be described as “sugar free” on food labels 4-47 Alternatives to Sugar • Saccharine and cancer • Aspartame and PKU Metabolism of Aspartame Sugar Alternatives on Food Labels High Fructose Corn Syrup Unlike carbohydrates made up of glucose, fructose does not stimulate the pancreas into producing insulin. Nor does it promote the production of leptin, a hormone made by fat cells. Under normal conditions, the amount of insulin and leptin in the body signal to the brain that you’ve had enough to eat Simple Carbohydrates: The Disaccharides Sucrose Sucrose = Glucose + Fructose *Table sugar *Found naturally in plants: sugar cane, sugar beets, honey, maple syrup *Sucrose may be purified from plant sources into Brown, White and Powdered Sugars. It could be like paying with pennies vs. paying with nickels. The whole thing could be like a wooden nickel or a trick. High Fructose Corn Syrup Simple Carbohydrates: The Monosaccharides 1. Glucose C6H12O6 • The essential energy source for all body functions. • • • Other names: Dextrose and Blood Sugar. A component of each disaccharide. The body’s main source of energy. Simple Carbohydrates: The Monosaccharides • Fructose: • The sweetest of all sugars – (1.5 X sweeter than sucrose) • Occurs naturally in fruits and honey – “the fruit sugar” Table 4.1 More and Less Refined Choices • Recommendations: – Choose more foods with less refined carbohydrates – Choose fewer foods with refined carbohydrates and added sugars 4-7 The Whole Grain Story • A whole grain is the entire kernel of grain including: – The bran: dietary fiber and vitamins – The germ: vitamin E, protein, fibers, riboflavin, thiamin, and B6 – The endosperm: starch, protein, some vitamins and minerals 4-8 Choosing Whole Grains 4-9 Choosing Whole Grains 4-10 More on Carbohydrates and Health • Diets high in sugars and refined starches increase the demand for insulin and may increase the risk for developing diabetes. • Diets high in whole grains and other unrefined carbohydrates may reduce the risk of heart disease. • Diets high in indigestible carbohydrates can relieve or prevent certain disorders that are caused by pressure in the lumen of the colon. 4-33