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Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression by Kunju Sridhar, Douglas T. Ross, Robert Tibshirani, Atul J. Butte, and Peter L. Greenberg Blood Volume 114(23):4847-4858 November 26, 2009 ©2009 by American Society of Hematology GEPs of MDS versus normal CD34+ marrow cells. Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology Distinctive classification of MDS from normal using PAM. As indicated (top panel), the classifier distinguishing these groups of persons required a minimum number of 39 genes (the arrow shows the inflection point, below which the misclassification error inc... Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology Multiclass analysis of gene expression in normal persons, sMDS, and tMDS. Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology Freedom from AML evolution for MDS patients classified by clinical and molecular features. Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology Differentially expressed RP expression in MDS subsets. Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology Expression of representative genes assessed by quantitative RT-PCR. Kunju Sridhar et al. Blood 2009;114:4847-4858 ©2009 by American Society of Hematology