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Transcript 
Membrane Proteins
Page 383
P
Structural formulas of some C18 fatty acids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 383
P
The Common Biological Fatty Acids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 384
P
Scanning electron micrograph of adipocytes.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 394
P
Lipid Compositions of Some Biological Membranesa
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 385
P
Molecular formula of glycerophospholipids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 385
P
The Common Classes of Glycerophospholipids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 386
P
The glycerophospholipid 1‐stearoyl‐2‐oleoyl‐3‐
phosphatidylcholine.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 387
P
Molecular formulas of sphingosine and dihydrosphingosine C18 alchools
dihydrosphingosine, C18 alchools. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 387
P
A sphingomyelin (sphingolipids). A sphingomyelin
(sphingolipids)
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 387
P
A sphingomyelin
A sphingomyelin. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 388
P
Ganglioside GM1. Structural formula with its sphingosine residue in Fischer projection.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 388
P
Ganglioside GM1. Ganglioside G
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 388
P
Cyclopentanoperhydrophenanthre
ne, the parent compound of steroids. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 389
P
Cholesterol. Structural formula with the standard numbering system.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 389
P
Cholesterol. (b) Space‐filling model with H white, C gray, and O red.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 395
P
Compositions of Some Biological Membranes.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 406
P
Asymmetric distribution of phospholipids in the human erythrocyte membrane
the human erythrocyte membrane.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 390
P
An oil monolayer at the air–water interface.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 390
P
Aggregates of single tailed lipids
Aggregates of single‐tailed lipids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 391
P
Bilayer formation by phospholipids
Bilayer formation by phospholipids.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 391
P
Lipid bilayers. An electron micrograph of a multilamellar phospholipid vesicle in which each layer is a lipid bilayer.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 391
P
Lipid bilayers. An electron micrograph of a liposome.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 392
P
Phospholipid diffusion in a lipid bilayer.
diffusion in a lipid bilayer
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 392
P
The fluorescence bleaches the fluorescent markers. (b) The
fluorescence bleaches the fluorescent markers (b)
The fluorescence of the bleached area. photobleaching recovery technique (a) An intense laser light pulse
recovery technique. (a) An intense laser light pulse Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 392
P
The fluorescence photobleaching recovery technique. The fluorescence recovery rate depends on the diffusion rate of y
p
the labeled molecule.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 393
P
Snapshot of a molecular dynamics simulation of a lipid bilayer consisting of dipalmitoyl phosphatidylcholine
bilayer consisting of dipalmitoyl phosphatidylcholine surrounded by water. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 393
P
SStructure of a lipid bilayer composed of f li id bil
d f
phosphatidylcholine and phosphatidylethanolamine as the temperature is lowered below bilayer’s transition h
i l
d b l bil
’
ii
temperature. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 395
P
Model of an integral membrane protein.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 395
P
A selection of the detergents used in biochemical manipulations.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 396
P
Schematic diagram of a plasma membrane.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 397
P
The amino acid sequence and membrane y
y gy p
location of human erythrocyte glycophorin A (polytopic).
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 397
P
A plot, for glycophorin A, of the calculated free energy change in transferring 20‐residue‐long α helical segments. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 398
P
Liver cytochrome b5 in association with a membrane (monotopic).
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 398
P
Molecular formula of retinal
Molecular formula of retinal.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 399
P
Structure of bacteriorhodopsin. The electron crystallography–based structure.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 399
P
Structure of bacteriorhodopsin. The X‐ray structure of a bacteriorhodopsin trimer.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 400
P
X‐Ray structure of the photosynthetic reaction center of Rps viridis
center of Rps. viridis. Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 401
P
X‐Ray crystal structure of the E. coli OmpF porin. A ribbon diagram of the monomer.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 401
P
X‐Ray crystal structure of the E. coli OmpF porin. The Cα backbone of the trimer.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 401
P
X‐Ray crystal structure of the E. coli OmpF porin. A space‐filling model of the trimer.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 401
P
X‐Ray structure of sheep cyclooxygenase‐1 showing its p p
proposed disposition in the endoplasmic reticulum p
p
membrane.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 403
P
Prenylated proteins. (a) A farnesylated protein and (b) a geranylgeranylated protein
and (b) a geranylgeranylated protein.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
Page 404
P
Core structure of the GPI anchors of proteins.
Voet Biochemistry 3e
© 2004 John Wiley & Sons, Inc.
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