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READERS’ FORUM Letters to the editor* Class II subdivision malocclusion We appreciate the efforts of Dr Janson and his colleagues for their research on Class II subdivision malocclusion; it has enriched the orthodontic literature. We followed with great interest their article, “Cephalometric evaluation of symmetric and asymmetric extraction treatment for patients with Class II subdivision malocclusions” (Janson G, Carvalho PEG, Cançado RH, de Freitas MR, Henriques JFC. Am J Orthod Dentofacial Orthop 2007;132:28-35). The results of the study were commendable with the exception of the upper lip retraction after incisor retraction when the groups were compared. The authors concluded from their results that upper lip retraction was significantly greater in group 2 compared with group 1, even though the maxillary incisor retraction amounts (angulation and linear) were not significantly different. That finding needs to be clarified by the authors, because previous studies have reported direct relationships between incisor retraction and upper lip changes associated with it.1,2 Because the amounts of linear upper lip retraction were similar in the groups (–2.11 mm in group 1 and –2.33 mm in group 2), the upper lip should have shown similar changes in both groups in contrast to the results of their study. Apart from hard-tissue changes, lip response also depends on lip morphology and its tonus. Oliver3 showed a high correlation between incisor retraction and lip movement in subjects with thin lips compared with subjects with thick lips. These factors should have been considered when evaluating upper lip response to incisor retraction in the asymmetric and symmetric extraction groups. Suruchi Jain Ashima Valiathan Manipal, India Am J Orthod Dentofacial Orthop 2008;133:4 0889-5406/$34.00 Copyright © 2008 by the American Association of Orthodontists. doi:10.1016/j.ajodo.2007.11.009 REFERENCES 1. Rudee DA. Proportional profile changes concurrent with orthodontic therapy. Am J Orthod 1964;50:421-33. 2. Roos N. Soft tissue profile changes in Class II treatment. Am J Orthod 1977;72:165-75. 3. Oliver BM. The influence of lip thickness and strain on upper lip response to incisor retraction. Am J Orthod 1982;82:141-9. metric and asymmetric extraction treatment for patients with Class II subdivision malocclusions.” Yes, we agree that a significant maxillary incisor retraction would be expected to be somehow associated with the significant upper lip retraction that we found. However, because it did not occur, we speculated that it could have resulted from the large standard deviations in the amount of maxillary incisor retraction. When extrapolating the correlation found between maxillary incisor retraction and upper lip retraction in the mentioned studies,1,2 one must notice that they were obtained between linear variables and therefore differently from our study. Additionally, the correlation coefficients obtained were 0.72652 and 0.421; these are not considered statistically high,3-7 and there were also large individual variations in the response of the soft tissues to changes in the underlying skeletal structures.1 Lip thickness and strain, as mentioned, also play roles.8 Therefore, under these circumstances, it is likely that the results we obtained are possible. Perhaps this explanation could have been added to the discussion. In the article, we did not further explore this topic because it was not our primary objective. However, it surely is an interesting issue to be investigated and clarified in the future. Guilherme Janson Rodrigo Hermont Cançado Bauru, SP, Brazil Am J Orthod Dentofacial Orthop 2008;133:4 0889-5406/$34.00 Copyright © 2008 by the American Association of Orthodontists. doi:10.1016/j.ajodo.2007.11.010 REFERENCES 1. Roos N. Soft-tissue profile changes in Class II treatment. Am J Orthod 1977;72:165-75. 2. Rudee DA. Proportional profile changes concurrent with orthodontic therapy. Am J Orthod 1964;50:421-33. 3. Le CT. Fundamentals of biostatistical inference. New York: Dekker; 1992. 4. Looney SW. Biostatistical methods. Totowa, NJ: Humana Press; 2002. 5. Selvin S. Practical biostatistical methods. Belmont, Calif: Duxbury Press; 1995. 6. Zar JH. Biostatistical analysis. 4th ed. Upper Saddle River, NJ: Prentice Hall; 1999. 7. Altman DG. Statistics in medical journals. Stat Med 1982;1: 59-71. 8. Oliver BM. The influence of lip thickness and strain on upper lip response to incisor retraction. Am J Orthod 1982;82:141-9. Authors’ response We thank Drs Jain and Valiathan for their constructive comments on our article, “Cephalometric evaluation of sym*The viewpoints expressed are solely those of the author(s) and do not reflect those of the editor(s), publisher(s), or Association. 4 Self-ligating brackets With great curiosity, I began reading the August issue of the AJO-DO. Had the orthodontic community actually taken an interest in research about self-ligation? I could hardly