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Publications, 2006 Department of Oncology, Lund University Hospital, Lund 1. Bjurberg M., Gustavsson A., Ohlsson T. and Brun E. FDG-PET in the detection of residual disease and relapse in patients with Hodgkin's lymphoma. Experience from a Swedish centre. Acta Oncol 2006;45(6):743-9. 2. Bradlow H. L., Jernstrom H., Sepkovic D. W., Klug T. L. and Narod S. A. Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16 alphahydroxyestrogen metabolites. Mol Genet Metab 2006;87(2):135-46. 3. Brans B., Linden O., Giammarile F., Tennvall J. and Punt C. Clinical applications of newer radionuclide therapies. Eur J Cancer 2006;42(8):994-1003. 4. Carlsson C., Bendahl P. O., Nilsson K. and Nilbert M. Benefits from membership in cancer patient associations: Relations to gender and involvement. Acta Oncol 2006;45(5):559-63. 5. Carlsson C., Nilbert M. and Nilsson K. Patients' involvement in improving cancer care: experiences in three years of collaboration between members of patient associations and health care professionals. Patient Educ Couns 2006;61(1):65-71. 6. Chickarmane V., Troein C., Nuber U. A., Sauro H. M. and Peterson C. Transcriptional Dynamics of the Embryonic Stem Cell Switch. PLoS Comput Biol 2006;2(9). 7. Clendenning M., Hampel H., Lajeunesse J., Lindblom A., Lockman J., Nilbert M., Senter L., Sotamaa K. and de la Chapelle A. Long-range PCR facilitates the identification of PMS2-specific mutations. Hum Mutat 2006;27(11):1155. 8. Dahlgren N. Ryggtavlans känsel felbeskriven i dermatomkartor. Läkartidningen 2006;103(47):3702-3703. 9. Davidsson J., Heidenblad M., Borg A. and Johansson B. Array-based comparative genomic hybridization characterization of cytogenetically polyclonal myeloid malignancies. Cancer Genet Cytogenet 2006;169(2):179-80. 10. Domanski H. A., Akerman M., Engellau J., Gustafson P., Mertens F. and Rydholm A. Fine-needle aspiration of neurilemoma (schwannoma). A clinicocytopathologic study of 116 patients. Diagn Cytopathol 2006;34(6):403-12. 11. Engleson J., Soller M., Panagopoulos I., Dahlen A., Dictor M. and Jerkeman M. Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy. BMC Cancer 2006;6:69. 12. Fernebro J., Bladstrom A., Rydholm A., Gustafson P., Olsson H., Engellau J. and Nilbert M. Increased risk of malignancies in a population-based study of 818 softtissue sarcoma patients. Br J Cancer 2006. 13. Fernebro J., Francis P., Eden P., Borg A., Panagopoulos I., Mertens F., VallonChristersson J., Akerman M., Rydholm A., Bauer H. C., Mandahl N. and Nilbert M. Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma. Int J Cancer 2006;118(5):1165-72. 14. Goldstein A. M., Chan M., Harland M., Gillanders E. M., Hayward N. K., Avril M. F., Azizi E., Bianchi-Scarra G., Bishop D. T., Bressac-de Paillerets B., Bruno W., Calista D., Cannon Albright L. A., Demenais F., Elder D. E., Ghiorzo P., Gruis N. A., Hansson J., Hogg D., Holland E. A., Kanetsky P. A., Kefford R. F., Landi M. T., Lang J., Leachman S. A., Mackie R. M., Magnusson V., Mann G. J., Niendorf K., Newton Bishop J., Palmer J. M., Puig S., Puig-Butille J. A., de Snoo F. A., Stark M., Tsao H., Tucker M. A., Whitaker L. and Yakobson E. High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. Cancer Res 2006;66(20):9818-28. 15. Goldstein A. M., Chan M., Harland M., Hayward N. K., Demenais F., Bishop D. T., Azizi E., Bergman W., Bianchi-Scarra G., Bruno W., Calista D., Cannon-Albright L. A., Chaudru V., Chompret A., Cuellar F., Elder D. E., Ghiorzo P., Gillanders E. M., Gruis N., Hansson J., Hogg D., Holland E. A., Kanetsky P. A., Kefford R. F., Landi M. T., Lang J. M., Leachman S., Mackie R. M., Magnusson V., Mann G., NewtonBishop J., Palmer J. M., Puig S., Puig-Butille J. A., Stark M., Tsao H., Tucker M. A., Whitaker L., Yakobson E., Study Group L. M. and Genomel M. G. Features associated with germline CDKN2A mutations: A GenoMEL study of melanoma-prone families from three continents. J Med Genet 2006. 16. Grafstrom G., Jonsson B. A., El Hassan A. M., Tennvall J. and Strand S. E. Rat testis as a radiobiological in vivo model for radionuclides. Radiat Prot Dosimetry 2006;118(1):32-42. 17. Gronwald J., Tung N., Foulkes W. D., Offit K., Gershoni R., Daly M., Kim-Sing C., Olsson H., Ainsworth P., Eisen A., Saal H., Friedman E., Olopade O., Osborne M., Weitzel J., Lynch H., Ghadirian P., Lubinski J., Sun P. and Narod S. A. Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update. Int J Cancer 2006;118(9):2281-4. 18. Gruvberger-Saal S. K., Cunliffe H. E., Carr K. M. and Hedenfalk I. Microarrays in breast cancer research and clinical practice - the future lies ahead. Endocrine-Related Cancer 2006;13:1017-1031. 19. Gruvberger-Saal S. K. and Parsons R. Is the small heat shock protein alphaB-crystallin an oncogene? J Clin Invest 2006;116(1):30-2. 20. Gustavsson P., Schoumans J., Staaf J., Jonsson G., Carlsson F., Kristoffersson U., Borg A., Nordenskjold M. and Dahl N. Hemizygosity for chromosome 2q14.2-q22.1 spanning the GLI2 and PROC genes associated with growth hormone deficiency, polydactyly, deep vein thrombosis and urogenital abnormalities. Clin Genet 2006;69(5):441-3. 21. Halvarsson B., Lindblom A., Rambech E., Lagerstedt K. and Nilbert M. The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer. Fam Cancer 2006. 22. Halvarsson B., Muller W., Planck M., Benoni A. C., Mangell P., Ottosson J., Hallen M., Isinger A. and Nilbert M. Phenotypic heterogeneity in hereditary nonpolyposis colorectal cancer: identical germline mutations associated with variable tumor morphology and immunohistochemical expression. J Clin Pathol 2006. 23. Heidenblad M., Hallor K. H., Staaf J., Jonsson G., Borg A., Hoglund M., Mertens F. and Mandahl N. Genomic profiling of bone and soft tissue tumors with supernumerary ring chromosomes using tiling resolution bacterial artificial chromosome microarrays. Oncogene 2006. 24. Heikkinen K., Rapakko K., Karppinen S. M., Erkko H., Knuutila S., Lundan T., Mannermaa A., Borresen-Dale A. L., Borg A., Barkardottir R. B., Petrini J. and Winqvist R. RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis 2006;27(8):1593-9. 25. Henriksson E., Baldetorp B., Borg A., Kjellen E., Akervall J., Wennerberg J. and Wahlberg P. p53 mutation and cyclin D1 amplification correlate with cisplatin sensitivity in xenografted human squamous cell carcinomas from head and neck. Acta Oncol 2006;45(3):300-5. 26. Hietala M., Sandberg T., Borg A., Olsson H. and Jernstrom H. Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women. Hum Reprod 2006. 27. Holmquist-Mengelbier L., Fredlund E., Lofstedt T., Noguera R., Navarro S., Nilsson H., Pietras A., Vallon-Christersson J., Borg A., Gradin K., Poellinger L. and Pahlman S. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 2006;10(5):413-23. 28. Honeth G., Staflin K., Kalliomaki S., Lindvall M. and Kjellman C. Chemokinedirected migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma. Exp Cell Res 2006;312(8):1265-76. 29. Isinger A., Bhat M., Borg A. and Nilbert M. CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum. BMC Cancer 2006;6:64. 30. Jacobsson M., Ellervik U., Belting M. and Mani K. Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides. J Med Chem 2006;49(6):1932-8. 31. Jernstrom H., Sandberg T., Bageman E., Borg A. and Olsson H. Insulin-like growth factor-1 genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating insulin-like growth factor-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families. Int J Gynecol Cancer 2006;16 Suppl 2:497. 32. Jernstrom H., Sellberg G., Borg A. and Olsson H. Differences in IGFBP-3 regulation between young healthy women from BRCAX families and those belonging to BRCA1/2 families. Eur J Cancer Prev 2006;15(3):233-41. 33. Johannsdottir H. K., Jonsson G., Johannesdottir G., Agnarsson B. A., Eerola H., Arason A., Heikkila P., Egilsson V., Olsson H., Johannsson O. T., Nevanlinna H., Borg A. and Barkardottir R. B. Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors. Int J Cancer 2006;119(5):1052-60. 34. Johansson A., Johansson T., Thompson M. S., Bendsoe N., Svanberg K., Svanberg S. and Andersson-Engels S. In vivo measurement of parameters of dosimetric importance during interstitial photodynamic therapy of thick skin tumors. J Biomed Opt 2006;11(3):34029. 35. Karppinen S. M., Barkardottir R. B., Backenhorn K., Sydenham T., Syrjakoski K., Schleutker J., Ikonen T., Pylkas K., Rapakko K., Erkko H., Johannesdottir G., Gerdes A. M., Thomassen M., Agnarsson B. A., Grip M., Kallioniemi A., Kere J., Aaltonen L. A., Arason A., Moller P., Kruse T. A., Borg A. and Winqvist R. Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 cancer cases: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies. J Med Genet 2006. 36. Kjellen E., Sasaki Y., Kjellstrom J., Zackrisson B. and Wennerberg J. Recombinant erythropoietin beta enhances growth of xenografted human squamous cell carcinoma of the head and neck after surgical trauma. Acta Otolaryngol 2006;126(5):545-7. 37. Klug T. L., Bageman E., Ingvar C., Rose C. and Jernstrom H. Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: A pilot study comparing pre- and post-operative levels. Mol Genet Metab 2006. 38. Kristensen I., Johnsson M., Lind J., Nilsson P. and Karlsson M. [Distance pediatric radiotherapy. Telemedicine a good tool to be used for discussions, exchange of experiences and competence]. Lakartidningen 2006;103(15-16):1188-90. 39. Laakso M., Tanner M., Nilsson J., Wiklund T., Erikstein B., Kellokumpu-Lehtinen P., Malmstrom P., Wilking N., Bergh J. and Isola J. Basoluminal carcinoma: a new biologically and prognostically distinct entity between basal and luminal breast cancer. Clin Cancer Res 2006;12(14 Pt 1):4185-91. 40. Lindgren D., Liedberg F., Andersson A., Chebil G., Gudjonsson S., Borg A., Mansson W., Fioretos T. and Hoglund M. Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q. Oncogene 2006;25(18):2685-96. 41. Link K., Moell C., Osterberg K., Persson R., Orbaek P., Garwicz S., Cavallin-Stahl E. and Erfurth E. M. Adult survivors of childhood acute lymphoblastic leukaemia with GH deficiency have normal self-rated quality of life but impaired neuropsychological performance 20 years after cranial irradiation. Clin Endocrinol (Oxf) 2006;65(5):617-25. 42. Magzoub M., Sandgren S., Lundberg P., Oglecka K., Lilja J., Wittrup A., Goran Eriksson L. E., Langel U., Belting M. and Graslund A. N-terminal peptides from unprocessed prion proteins enter cells by macropinocytosis. Biochem Biophys Res Commun 2006;348(2):379-85. 43. Malander S., Rambech E., Kristoffersson U., Halvarsson B., Ridderheim M., Borg A. and Nilbert M. The contribution of the hereditary nonpolyposis colorectal cancer syndrome to the development of ovarian cancer. Gynecol Oncol 2006;101(2):238-43. 44. Merletti F., Richiardi L., Bertoni F., Ahrens W., Buemi A., Costa-Santos C., Eriksson M., Guenel P., Kaerlev L., Jockel K. H., Llopis-Gonzalez A., Merler E., Miranda A., Morales-Suarez-Varela M. M., Olsson H., Fletcher T. and Olsen J. Occupational factors and risk of adult bone sarcomas: a multicentric case-control study in Europe. Int J Cancer 2006;118(3):721-7. 45. Nimeus E., Malmstrom J., Johnsson A., Marko-Varga G. and Ferno M. Proteomic analysis identifies candidate proteins associated with distant recurrences in breast cancer after adjuvant chemotherapy. J Pharm Biomed Anal 2006. 46. Nimeus-Malmstrom E., Ritz C., Eden P., Johnsson A., Ohlsson M., Strand C., Ostberg G., Ferno M. and Peterson C. Gene expression profilers and conventional clinical markers to predict distant recurrences for premenopausal breast cancer patients after adjuvant chemotherapy. Eur J Cancer 2006. 47. Norrgren K., Sjolin M., Bjorkman S., Areberg J., Johnsson A., Johansson L. and Mattsson S. Comparative renal, hepatic, and bone marrow toxicity of Cisplatin and radioactive Cisplatin (191Pt) in Wistar rats. Cancer Biother Radiopharm 2006;21(5):528-34. 48. Palsson S., Stenram U., Thompson M. S., Vaitkuviene A., Poskiene V., Ziobakiene R., Oyama J., Deweert M. J., Gustafsson U., Bendsoe N., Andersson-Engels S., Svanberg S. and Svanberg K. Methods for detailed histopathological investigation and localization of biopsies from cervix uteri to improve the interpretation of autofluorescence data. J Environ Pathol Toxicol Oncol 2006;25(1-2):321-40. 49. Paulsson K., Heidenblad M., Morse H., Borg A., Fioretos T. and Johansson B. Identification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia. Leukemia 2006. 50. Paulsson K., Heidenblad M., Strombeck B., Staaf J., Jonsson G., Borg A., Fioretos T. and Johansson B. High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration. Leukemia 2006;20(5):840-6. 51. Rennstam K. and Hedenfalk I. High-throughput genomic technology in research and clinical management of breast cancer. Molecular signatures of progression from benign epithelium to metastatic breast cancer. Breast Cancer Res 2006;8(4):213. 52. Ringberg A., Bageman E., Rose C., Ingvar C. and Jernstrom H. Of cup and bra size: reply to a prospective study of breast size and premenopausal breast cancer incidence. Int J Cancer 2006;119(9):2242-3; author reply 2244. 53. Salnikov A. V., Heldin N. E., Stuhr L. B., Wiig H., Gerber H., Reed R. K. and Rubin K. Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. Int J Cancer 2006. 54. Scheele S., Sasaki T., Arnal-Estape A., Durbeej M. and Ekblom P. Monoclonal antimouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain. Matrix Biol 2006. 55. Schoumans J., Johansson B., Corcoran M., Kuchinskaya E., Golovleva I., Grander D., Forestier E., Staaf J., Borg A., Gustafsson B., Blennow E. and Nordgren A. Characterisation of dic(9;20)(p11-13;q11) in childhood B-cell precursor acute lymphoblastic leukaemia by tiling resolution array-based comparative genomic hybridisation reveals clustered breakpoints at 9p13.2 and 20q11.2. Br J Haematol 2006. 56. Schoumans J., Wincent J., Barbaro M., Djureinovic T., Maguire P., Forsberg L., Staaf J., Thuresson A. C., Borg A., Nordgren A., Malm G. and Anderlid B. M. Comprehensive mutational analysis of a cohort of Swedish Cornelia de Lange syndrome patients. Eur J Hum Genet 2006. 57. Stahl O., Eberhard J., Jepson K., Spano M., Cwikiel M., Cavallin-Stahl E. and Giwercman A. Sperm DNA integrity in testicular cancer patients. Hum Reprod 2006. 58. Szymanowska A., Jassem E., Dziadziuszko R., Borg A., Limon J., Kobierska-Gulida G., Rzyman W. and Jassem J. Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism. Lung Cancer 2006;52(1):9-14. 59. Takao K., Rickhag M., Hegardt C., Oredsson S. and Persson L. Induction of apoptotic cell death by putrescine. Int J Biochem Cell Biol 2006;38(4):621-8. 60. Tanner M., Isola J., Wiklund T., Erikstein B., Kellokumpu-Lehtinen P., Malmstrom P., Wilking N., Nilsson J. and Bergh J. Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracyclinebased adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. J Clin Oncol 2006;24(16):2428-36. 61. Thompson M. S., Andersson-Engels S., Svanberg S., Johansson T., Palsson S., Bendsoe N., Derjabo A., Kapostins J., Stenram U., Spigulis J. and Svanberg K. Photodynamic therapy of nodular Basal cell carcinoma with multifiber contact light delivery. J Environ Pathol Toxicol Oncol 2006;25(1-2):411-24. 62. Troein C., Vallon-Christersson J. and Saal L. H. An introduction to BioArray Software Environment. Methods Enzymol 2006;411:99-119. 63. Wagenius M., Borg A., Johansson L., Giwercman A. and Bratt O. CHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden. Scand J Urol Nephrol 2006;40(1):23-5. 64. Villman K., Sjostrom J., Heikkila R., Hultborn R., Malmstrom P., Bengtsson N. O., Soderberg M., Saksela E. and Blomqvist C. TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer. Acta Oncol 2006;45(5):590-6. Book Chapter 1. Brown K. M., Hedenfalk I. and Trent J. cDNA Microarrays in Cancer Research. In: DeVita V. T., Hellman S. and Rosenberg S. A., eds. Cancer: Principles and Practise of Oncology, 7th Edition, 2006: 13-25. 2. Carlsson C. Patientföreningarna som företrädare och röst. In: Svedberg I. L. and Trädgård L., eds. Det civila samhället som forskningsfält. Nya avhandlingar i ett nytt sekel. Stockholm, 2006: 38-49. 3. Hedenfalk I. Gene Expression Profiling Can Distinguish Tumor Subclasses of Breast Carcinomas. In: Hofmann W. K., ed. Gene Expression Profiling by Microarrays Clinical Implications, 2006: 132-161. 4. Tennvall J., Lundell G. and Wallin G. Management of Anaplastic Thyroid Cancer. In: Mazzaferri E. L., Harmer C., Mallick U. and Kendall-Tayler P., eds. Practical Management of Thyroid Cancer. London: Springer-Verlag, 2006: 403-409.