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International Congress on Molecular Targeting Therapy May 2nd - 5th, 2012 Kibbutz Hagoshrim, Israel WEDNESDAY, MAY 2, 2012 14:30 Registration & check in 16:00-17:00 Cocktail Reception & Exhibition 17:00-17:15 Opening Ceremony - Oren hall Dr. O. Embon, Director, Ziv Medical Center, Zefat Prof. J. Zidan , Congress President Dr. W. Mermershtain, Secretary, ISCORT Prof. E. Robinson, Chairman, Israel Cancer Association Prof. R. Tur-Kaspa, Dean, Faculty of Medicine in the Galilee, Bar Ilan University 17:15-18:00 Educational Lecture - Oren hall Chair: Prof. R. Catane, Sheba MC, Tel Hashomer EGRF and HER-2: Open Challenges in Cancer Therapy Prof. Y. Yarden, Biological Regulation Department, Weizmann Institute, Rehovot 18:00-18:30 Educational Lecture - Oren hall Chair: Prof. A. Kuten, Rambam MC, Haifa Immunoconjugates for Targeting Therapy of Solid Tumors Prof. R. Hassan, Laboratory of Molecular Biology, National Cancer Institute, NIH Bethesda, USA 18:30-19:00 Educational Lecture - Oren hall Chair: Prof. M. Inbar, Sourasky MC, Tel-Aviv Micro RNAs in Oncology Dr. N. Shomron, Tel Aviv University, Tel- Aviv 19:00-20:30 Dinner 20:30-23:30 Social Event THURSDAY, MAY 3, 2012 07:00 Breakfast 08:00-18:00 Registration & Exhibition 08:00-08:30 Educational Lecture - Oren hall Chair: Dr. I. Haviv, Faculty of Medicine, Bar Ilan University,Zefat Identifying novel targets for Ovarian cancer, using functional Genomics screens Over Amplified Genomes Regions Prof. I. Campbell, Peter MacCallum Cancer Centre, Melbourne, Australia 08:30-09:00 Invited Lecture - Oren hall (Novartis) Chair: Dr. K. Drumea, Rambam MC, Haifa Endocrine Resistant and Solutions in Breast Cancer Dr. B. Kaufman, Sheba MC, Tel Hashomer 09:00-09:30 Educational Lecture - Oren hall Chair: Dr. A. Agbarya, Rambam MC, Haifa Tumor Initiating Cells from Different Tumor Types Display Diverse Angiogenic Properties: Implications for Antiangionetic Treatment Efficacy Dr. Y. Shaked, Molecular pharmacology, Faculty of Medicine, Technion, Haifa, Israel 09:30-10:10 Invited Lecture - Oren hall (Roche) Chair: Prof. T. Peretz, Hadassah MC, Jerusalem The Quest for a Predictive Biomarker in Cancer Treatment Dr. S. Scherer, Head, Global Biomarker at Hoffmann-La Roche / Genentech, 10:10-10:40 Educational Lecture - Oren hall Chair: Prof. R. Ben-Yosef, Rambam MC, Haifa Biologic Drugs and Imaging: How they Affect Imaging Prof. D. Groshar, Rabin MC, Petah Tikva and Assuta MC, Tel-Aviv 10:45-11:20 Coffee Break & Exhibition ( 10:50-11:20: Meet the Expert - Jasmine hall (Eli-Lilly) NSCLC - Is It a Single Disease? Dr. M. Gips, Shaare-Zedek Medical Center, Jerusalem ) 11:20-11:50 Invited Lecture - Oren hall (Roche) Chair: Prof. B. Klein, Assuta MC, Tel-Aviv& Haifa Treatment of mCRC Patients in the Biologic Therapy Era Dr. E. Shmueili, Sourasky MC, Tel Aviv 11:50-12:30 Educational Lecture - Oren hall (AROME) Chair: E. Fenig, Rabin MC, Petach-Tikva The Treatment of Locally Advanced Head & Neck Cancer: Present Status in Combining Anti-EGFR Treatment and Chemotherapy Prof. E. M. Ozsahin, University of Lausanne Medical Center, Lausanne, Switzerland 12:30-13:00 Invited Lecture - Oren hall (Novartis) Chair: Dr. R. Berger, Sheba MC, Tel Hashom Sequential Therapy (TKI-mTOR-TKI) and Targeted Therapy in Renal Cancer Prof. E. Calvo, Centro Integral Oncologico Clara Campal, Madrid, Spain 13:00-13:30 Educational Lecture - Oren hall Chair: Prof. H. Gutman, Rabin MC, Petach-Tikva The Peri-Operative Phase in the Management of Breast Cancer: A New Window of Opportunity for Molecular Targeting Therapy Prof. M. Baum, University College of London, London, UK 13:30-14:30 Lunch Buffet & Exhibition (14:00-14:30: Meet the Expert - Jasmine hall (Astra Zeneca) Faslodex Dr. B. Kaufman, Sheba Medical Center, Tel Hashomer) 14:30-15:00 Invited Lecture - Oren hall (Sanofi Aventis) Chair: Dr. B. Uzieli, Hadassah MC, Jerusalem Molecular Targeting Therapy in CRC Prof. D. Aderka, Sheba MC, Tel Hashomer 15:00-15:30 Educational Lecture - Oren hall Chair: Dr. H. hayet, Wolfson MC, Holon CD30 a New Target in Hematologic Malignancies Prof. J. Rosenblatt, Sylvester Comprehensive Cancer Center, University of Miami, Miami, USA 15:30-16:00 Invited lecture - Oren hall (Astra Zeneca) Chair: Dr. E. Gez, Sourasky MC, Tel-Aviv Issues Correlated to EGFR in the Treatment of Lung Cancer Prof. H. Nechushtan, Hadassah MC, Jerusalem 16:00-16:30 Coffee Break & Exhibition 16:30-17:00 Educational Lecture - Oren hall Chair: Dr. F. Barak, Barzilai MC, Ashkelon Dermal Side Effects of Molecular Targeting Therapy Dr. S. Merims, Hadassah MC, Jerusalem 17:00-18:00 Abstracts Presentations - Oren hall 17:00-17:15 17:15-17:30 17:30-17:45 Chair: Dr. I. Wolf, Sheba MC, Tel Hashomer The Effect of Radiation on Prostate Cancer Cells is Enhanced by Pretreatment with Vitamin D and Sodium Valporate Prof. S. Shany, Faculty of Health Science, Ben Gurion University and Soroka MC, Beer Sheva Ceacam1-Targeted Therapy with a Monoclonal Anti body as a Novel Therapeutic Approach for Malignanat Melanoma Dr. G. Markel, Sheba MC, Tel Hashomer Chair: Dr. S. Belan, Rambam MC, Haifa& The Use of Anthraquinone Derivatives as a Targeting Radiosensitisers, Preliminary Results in Vitro and Vivo Dr. M. Schaffer, Ziv MC, Zefat 17:45-18:00 Topoisomerase I as a New Target of Erlotinib in Breast and Prostate Cancer Cell Lines Dr. R. Peleg, Faculty of Health Science, Ben Gurion University and Soroka MC, Beer Sheva 18:00-18:30 Open dialogue between experts (lecturers) and audience - Oren hall Chair: Dr. W. Mermershtain, Soroka MC, Beer Sheva 20:00 Gala Dinner & Social Event: Jewish Traditional Music & Folklore Arab Music and Dance (Dabka) FRIDAY, MAY 4, 2012 07:00-08:00 Breakfast 08:00- 14:00 Registration & Exhibition 08:00-08:40 Educational Lecture - Oren hall Chair: Dr. M. Wygoda, Hadassah MC, Jerusalem PARP inhibitors, Antiangiogenesis and Folate Receptors Targeting in Gynecological Cancers Prof. J. Ledermann, UCL Cancer, London, UK 08:40-09:10 Educational Lecture - Oren hall Chair: Dr. S. Nasrallah, Western Galilee MC, Naharia Molecular Targeting Therapy in Melanoma Prof. J. Schachter, Sheba MC, Tel Hashomer 09:10-09:30 Educational Lecture - Oren hall Chair: Prof. A. Kuten, Rambam MC, Haifa Discordance of Molecular Targets in Metastases and Primary Tumors Prof. J. Zidan, Ziv MC , Zefat 09:30-10:00 Invited Lecture - Oren hall (Roche) Chair: Dr. Y. Merrick, Laniado MC, Netania Biosimilars – Simply Not the Same! Dr. N. Asna, Sourasky MC, Tel-Aviv 10:00-10:30 Educational Lecture - Oren hall Chair: Dr. O. Hussein, Ziv MC, Zefat Non Dermal; Systemic Side Effects of Molecular Targeting Therapy Dr. D. Katz, Hadassah MC, Jerusalem 10:30-11:00 Coffee Break & Exhibition 11:00-11:30 Educational Lecture - Oren hall Chair: Prof. E. Robinson, Chairman, Israel Cancer Association The DNA Damage Response: Clues to the Response to DNA-Directed Therapies and Potential Targets Prof. Y. Shiloh, Tel Aviv University, Tel-Aviv 11:30-12:00 Educational Lecture - Oren hall Chair: Prof. H. Nechushtan, Hadassah MC, Jerusalem Inherited Predisposition to Breast Cancer - New Genes Novel Targets Prof. E. Friedman, Sheba MC, Tel Hashomer 12:00-12:30 Educational Lecture - Oren hall Chair: Prof. A. Shani, Sheba MC, Tel Hashomer Targeting Therapy in Sarcoma Prof. O. Merimsky, Sourasky MC , Tel -Aviv 12:30-13:00 Educational Lecture - Oren hall (AROME) Chair: Dr. N. Siegelmann- Danieli , Maccabi Health Care . Breast Cancer Radiotherapy and Targeted Therapy Interactions Prof. N. Bese, Istanbul University, Cerrahpasa Medical School. Istanbul, Turky. 13:00-13:30 Educational Lecture - Oren hall Chair: Dr. A. Hadari, Ziv MC, Zefat Genetic analysis of tumors using novel DNA gene chips for personalize target therapy Prof. D. Bercovich, Tel Hai Academic College, Tel Hai 13:30-13:40 Closings Remarks - Oren hall Prof. J. Zidan, Ziv MC, Zefat 13:40-14:30 Lunch Buffet 14:30-18:30 Galilee Sightseeing Tour 19:00-23:30 Dinner & Entertainment Entrance of Sabbath (Saturday): 18:54 SATURDAY, MAY 5, 2012 07:00-09:00 Breakfast 09:00-10:00 Plenary Lecture - Oren hall Chair: Dr. W. Mermershtain, Soroka MC, Beer Sheva History of Cancer Prof. Y. Cohen, Ben Gurion University, Beer Sheva 10:30-12:30 Walking Tour 13:00-14:30 Lunch 14:30-19:00 Check Out