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Jeff Holmes
Angelini ED, Homma S, Pearson G, Holmes JW, Laine AF. Segmentation of real-time
three-dimensional ultrasound for quantification of ventricular function: A clinical study on
right and left ventricles. Ultrasound Med Biol. 2005 Sep;31(9):1143-58.
Herz SL, Ingrassia CM, Homma S, Costa KD, Holmes JW. Parameterization of left
ventricular wall motion for detection of regional ischemia. Ann Biomed Eng. 2005
Jul;33(7):912-9.
Holmes JW, Borg TK, Covell JW. Structure and mechanics of healing myocardial
infarcts.
Annu Rev Biomed Eng. 2005;7:223-53. Review.
Derderian CA, Bastidas N, Lerman OZ, Bhatt KA, Lin SE, Voss J, Holmes JW, Levine
JP, Gurtner GC. Mechanical strain alters gene expression in an in vitro model of
hypertrophic scarring. Ann Plast Surg. 2005 Jul;55(1):69-75; discussion 75.
Klotz S, Barbone A, Reiken S, Holmes JW, Naka Y, Oz MC, Marks AR, Burkhoff D. Left
ventricular assist device support normalizes left and right ventricular beta-adrenergic
pathway properties.
J Am Coll Cardiol. 2005 Mar 1;45(5):668-76.
Holmes JW, Borg TK, Covell JW. Structure and Mechanics of Healing Myocardial
Infarcts.
Annu Rev Biomed Eng. 2004 Jul 8;
Quinn TA, Cabreriza SE, Blumenthal BF, Printz BF, Altmann K, Glickstein JS, Snyder
MS, Mosca RS, Quaegebeur JM, Holmes JW, Spotnitz HM. Regional functional
depression immediately after ventricular septal defect closure. J Am Soc Echocardiogr.
2004 Oct;17(10):1066-72.
Holmes JW. Determinants of left ventricular shape change during filling. J Biomech Eng.
2004 Feb;126(1):98-103.
Holmes JW. Candidate mechanical stimuli for hypertrophy during volume overload. J
Appl Physiol. 2004 Oct;97(4):1453-60. Epub 2004 May 28.
Holmes JW, Borg TK, Covell JW. Structure and mechanics of healing myocardial
infarcts. Annu Rev Biomed Eng. 2005;7:223-53. Review.
Costa KD, Lee EJ, Holmes JW. Creating alignment and anisotropy in engineered heart
tissue: the role of boundary conditions in a model three-dimensional culture system.
Tissue Eng. 2003 Aug;9(4):567-77.
Holmes JW, Hünlich M, Hasenfuss G. Energetics of the Frank-Starling effect in rabbit
myocardium: economy and efficiency depend on muscle length. Am J Physiol Heart Circ
Physiol 283:H324-H330, 2002.
Knezevic V, Sim AJ, Borg TK, Holmes JW. Isotonic biaxial loading of fibroblastpopulated collagen gels: a versatile, low-cost system for the study of mechanobiology.
Biomech Model Mechanobiol 1:59-67, 2002.
Angelini A, Laine AF, Takuma S, Holmes JW, Homma S. LV volume quantification via
spatio-temporal analysis of 3D real-time echocardiography. IEEE Trans Med Imaging
20:457-469, 2001.
Costa KD, Holmes JW, McCulloch AD. Modeling cardiac mechanical properties in three
dimensions. Phil Trans Royal Soc London A 359:1233-1250, 2001.
Barbone A, Holmes JW, Heerdt PM, The AHS, Naka Y, Joshi N, Daines M, Marks AR,
Oz MC, Burkhoff D. Comparison of right and left ventricular responses to left ventricular
assist device support in patients with severe heart failure: a primary role of mechanical
unloading underlying reverse remodeling. Circulation 104:670-675, 2001.
Barbone A, Oz MC, Burkhoff D, Holmes JW. Normalized diastolic properties after left
ventricular assist result from reverse remodeling of chamber geometry. Circulation
104(Suppl I): I-229-I-232, 2001.
Zimmerman SD, Karlon WJ, Holmes JW, Omens JH, Covell JW. Structural and
mechanical factors influencing infarct scar collagen organization. Am J Physiol Heart
Circ Physiol 278:H194-H200, 2000.
Burkhoff D, Holmes JW, Madigan JD, Barbone A, Oz MC. Left ventricular assist deviceinduced reverse ventricular remodeling. Prog Cardiovasc Dis 43:19-26, 2000.
Heerdt P, Holmes JW, Cai B, Barbone A, Madigan J, Reiken S, Lee DL, Oz MC, Marks
AR, Burkhoff D. Chronic unloading by left ventricular assist device reverses abnormal
gene expression in end-stage heart failure: reverse molecular remodeling. Circulation,
102:2713-2719, 2000.
Meyer M, Keweloh B, Güth K, Holmes JW, Pieske B, Lehnart S, Just H, Hasenfuss G.
Frequency-dependence of myocardial energetics in failing human myocardium as
quantitated by a new method for the measurement of oxygen consumption in muscle
strip preparations. J Mol Cell Cardiol 30(8):1459-1470, 1998.
Holmes JW, Nunez JA, Covell JW. Functional implications of myocardial scar structure.
Am J Physiol Heart Circ Physiol 272:H2123-H2130, 1997.
Takayama Y, Holmes JW, Legrice IJ, Covell JW. Enhanced regional deformation at the
anterior papillary muscle insertion site after chordal transection. Circulation 93(3):585593, 1996.
Holmes JW, Covell JW. Collagen fiber orientation in myocardial scar tissue. Cardiovasc
Pathobiol 1:15-22, 1996.
Legrice IJ, Takayama Y, Holmes JW, Covell JW. Impaired subendocardial function in
tachycardia induced cardiac failure. Am J Physiol Heart Circ Physiol 268: H1788-H1794,
1995.
Holmes JW, Takayama Y, Legrice IJ, Covell JW. Depressed regional deformation near
anterior papillary muscle. Am J Physiol Heart Circ Physiol 269: H262-H270, 1995.
Holmes JW, Yamashita H, Waldman LK, Covell JW. Scar remodeling and transmural
deformation after infarction in the pig. Circulation 90(1): 411-420, 1994.