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Hyperglycemic Stress and Carbon Stress in Diabetic Glucotoxicity
Xiaoting Luo 1, 2 ;Jinzi Wu 1 ;Siqun Jing 1, 3 ;Liang-Jun Yan 1 ;
1 Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort
Worth, TX 76107, USA ; 2 Department of Biochemistry and Molecular Biology, Gannan Medical University, Ganzhou, Jiangxi province,
China, 341000 ; 3 College of Life Sciences and Technology, Xinjiang University, Urumqi, Xinjiang, China, 830046 ;
Figure 3. Summary of insulin-stimulated biological processes. Hyperglycemia-induced secretion of insulin can mediate numerous biological processes such as glucose
uptake, activation of Na + K + pumps, synthesis of fatty acid from acetyl-CoA and glycogen from glucose, amino acid uptake, gene expression, and protein synthesis. Figure
adapted from reference #cod#x0005B; 58 #cod#x0005D;.
null,null,7(1),90-110. Doi:10.14336/AD.2015.0702