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CURRICULUM VITAE Ban Mishu Allos, M.D. Address Division of Infectious Diseases A-2200 Medical Center North Vanderbilt University School of Medicine Nashville, TN 37232 Telephone Fax e-mail (615) 322-2035 (615) 343-6160 [email protected] Education 1977-1981 College: Emory University, Atlanta, GA Degree: B.A. Majors: American History, Chemistry 1981-1985 Medical School: University of Tennessee College of Medicine, Memphis, TN Degree: M.D. 1985-1988 Residency: Internal Medicine Loyola University School of Medicine, Chicago, IL 1988-1990 Epidemic Intelligence Service Officer Division of Field Services, assigned to Tennessee Dept. of Health Centers for Disease Control, Atlanta, GA 1989-1991 Residency: Preventive Medicine Enteric Diseases Branch, Bacterial Diseases Division Centers for Disease Control, Atlanta, GA 1991-1993 Fellowship: Infectious Diseases Vanderbilt University School of Medicine, Nashville, TN Uniformed Services: Commissioned Officer, Lieutenant Commander United States Public Health Service, 1988-1991 Licensure and Board Certifications: American Board of Internal Medicine, Internal Medicine, 1989 American Board of Internal Medicine, Infectious Diseases, 1996. Recertified, 2005 Illinois: 1985-1990 Tennessee: 1990-present Academic appointments: Assistant Professor, Division of Infectious Diseases, Department 1 of Medicine Assistant Professor, Department of Preventive Medicine Vanderbilt University School of Medicine Hospital appointments Divisional Compliance Expert (DCE), member 2001-present Chair, 2010- present Awards and honors: National Public Health Service Commissioned Officer Award, 1988 U.S. Public Health Service Citation, 1989, 1991 President, International Campylobacter Society, 1996-1998 Guest editor, Development of Guillain-Barre syndrome following Campylobacter infection. Journal of Infectious Diseases 1997;176:S91-S200. Guest editor, FoodNet and Surveillance of Foodborne Disease in the United States. Clin Infect Dis 2004;38 Suppl 3:S115-317. Local: John S. Sergent Award for Excellence in Teaching (Small Group Setting) (2007-2008) Member, Academy for Excellence in Teaching – 2008- present Professional organizations: Member, Infectious Diseases Society of Tennessee Member, American Society for Microbiology 1994-2000 Member, Infectious Diseases Society of America (IDSA) Professional activities: Intramural: Division of Infectious Diseases Fellowship, Director: 1998-2004 Institutional Review Board Subcommittee, member: 1999- 2009 Institutional Review Board Subcommittee, vice-chair: 2002-2007 Dept of Medicine, Divisional Compliance Expert (DCE) Member. 2000 –present Chair, 2010-present ID Fellowship Selection Committee, member: 1998-present Medical School Admissions Screener, 2004-2011 Medical School Admissions Committee 2011- present Progress and Promotions Committee, 2005-2009 Medical School Curriculum Committee, 2006- 2008, 2010-present American Medical Women’s Association, mentor, 2005 – present Medical School Student advisor, 1995-2007 Medical School College Mentor, Gabbe College, 2007-present 2 School of Medicine Faculty Advisory Council, 2007-2009 Extramural: International Campylobacter Society, President, 1996-1998 Infectious Diseases Society of America (IDSA) Public Policy committee, member, 2001-2004 CDC’s Advisory Committee for Immunization Practices, member, 2003-2007 CDC’s Advisory Committee for Immunization Practices, Chair of the Influenza Working Group 2003-2007 USMLE part 1, Pathology test item writer 2008- 2010 Editorial responsibilities Journal reviewer: American Journal of Epidemiology American Journal of Medicine American Journal of Public Health Annals of Internal Medicine Annals of Neurology Antimicrobial Agents and Chemotherapy Clinical Infectious Diseases European J of Clinical Microbiology and Infectious Diseases Infection Control and Hospital Epidemiology Infection and Immunity International Journal of Epidemiology Journal of the American Medical Association Journal of Endotoxin Research Journal of Infectious Diseases Journal of Neurology, Neurosurgery, and Psychiatry Western Journal of Medicine Grant Reviewer: U.S. Centers for Disease Control and Prevention Guest Editor: Development of Guillain-Barre Campylobacter infection. Journal 1997;176:S91-S200. syndrome of Infectious following Diseases Studies of Foodborne Infectious Diseases in the United States. Findings from the Foodborne Diseases Active Surveillance Network (FoodNet) of the Emerging Infections Program. Clin Infect Dis 2004;38 Suppl 3:S115-317 Teaching activities Medical school courses: 2001-present Section director, Medical students’, first year microbiology course (bacteriology) 3 1994-2008 Annual lectures on outbreaks of tuberculosis, hepatitis A, in Preventive Medicine course 1995-present Microbial Topic small group leader 2005-present: Course director, Capstone course (required, fourth year medical school course) 2008-2010 Foundations of the Profession small group leader 2009- present: Annual lectures in DD&T course on UTI, acute infectious diarrhea 2010-present Section director, DD&T (Antimicrobial agents) 2010-present Colloquium in Medicine Clinical teaching Regularly supervise residents and fellows on the ID consult service and in the ID clinic Research teaching Regularly participate as a member of fellows’ mentoring committees. Extramural activities Preceptor for AIDS Outreach Program 1998-1999 (organized and trained medical students to teach area middle and high school students about AIDS prevention) Civic and political activities Testified about the association between C. jejuni infection and GBS in front of a U.S. Congressional Subcommittee, Washington D.C., 1996. Invited Lectures Interscience Conference on Antimicrobial Agents and Chemotherapy. 29th meeting, Houston, TX, September 1989. Epidemic Intelligence Service Conference, Centers for Disease Control. 1990. Atlanta, GA, April International AIDS Conference, San Francisco, CA, June 1990. National Institutes of Health Symposium on Guillain-Barre syndrome, Bethesda, MD, June 1991. American Society of Tropical Medicine and Hygiene, Boston, MA, April 1991. American Society of Microbiology, 91st Annual Meeting, Dallas, TX, May 1991. Infectious Diseases Society of America, Annaheim, CA, October 1992. Interscience Conference on Antimicrobial Agents and Chemotherapy, 32nd meeting, Annaheim, CA October 1992. 4 University of Tennessee College of Medicine, Memphis, TN, March 1992, 1993. National Institutes of Health (National Institute of Neurologic Diseases and Stroke) International Symposium on GBS and Guillain-Barre-like syndromes, Wurzburg, Germany, February 1993. American Society for Microbiology. 93rd Annual Meeting, Atlanta, GA, May 1993. International Workshop on Campylobacter, Helicobacter, and Related Organisms, VIIth annual meeting, Brussels, Belgium September 1993. Infectious Diseases Society of America, New Orleans, LA October 1993. Interscience Conference on Antimicrobial Agents and Chemotherapy, 33rd meeting, Orleans, LA, October 1993. New American Gastroenterologic Association, Annual Meeting, Boston, MA, October 1993. Medical Surgical Grand Rounds. Grant Hospital. Cincinnati, Ohio, January 1994. American Society of Microbiology, 94th Annual Meeting, Las Vegas, NV, May 1994. National Institutes of Health, Bethesda, MD, August 1994. Infectious Diseases Society of America, Orlando, FL, September 1994. American Society of Microbiology, 95th Annual Meeting, Washington D.C., May 1995. Campylobacter, Helicobacter, and related organisms, VIIIth International Meeting, Winchester, England, July 1995. National Institutes of Health. Symposium on Campylobacter and the Guillain-Barre syndrome. Bethesda, MD, August 1996. American Society of Microbiology, Philadelphia Chapter, Philadelphia PA, December 1997. American Society of Microbiology, 97th Annual Meeting, Miami, FL, May 1997. Annual Meeting of the Infectious Diseases Society of Tennessee, Nashville, TN, September 1997. Tennessee Public Health Conference III. Gatlinburg, TN. September 1998. Infectious Diseases Society of America. November 1998. Invited Plenary Session Speaker. Denver, CO. Workshop on Campylobacter, Helicobacter, and related organisms. Xth International Workshop, Plenary Session Chair. Baltimore, MD. August 1999. 5 American Society of Microbiology, 100th Annual Meeting, Los Angeles, CA, May 2000. Intl Assn for Food Protection. 94th Annual Meeting, Orlando, FL. July 2007. Invited speaker. American Association of Medical Colleges, Learning Communities Institute Meeting, Innovations and Dilemmas in Medical School Learning Communities, Denver, CO, November 2011 Grant awards Award title: Muscular Dystrophy Association Fellowship Award Funding agency: Muscular Dystrophy Association Project title: Association of Campylobacter infection and GBS Role in project: Principal investigator Dates: 1992-1994 Budget: $53,000 (direct costs) Award title: K08-NS01709 (Clinical Investigator Award) Funding agency: National Institutes of Health Project title: Campylobacter jejuni as a cause GBS Role in project Principal investigator Dates: 1993-1998 Budget: $360,777 (direct costs) Award Title: Emerging Infectious Diseases Program Grant Funding agency: Centers for Disease Control and Prevention Project title: Campylobacter infection and the Guillain-Barre Syndrome Role in project: Principal investigator (of sub-project) Dates: 1999-2004 Budget: $1,024,294 (sub-project direct costs) PUBLICATIONS Reviewed Contributions 1. Mishu B, Hadler SC, Boaz VA, Hutcheson RH, Horan JM, Schaffner W. Foodborne hepatitis A: Evidence that microwaving reduces risk? J Infect Dis 1990;162:655-658. 2. Mishu B, Schaffner W, Horan JM, Wood LH, Hutcheson RH, McNabb PC. A surgeon with AIDS: lack of evidence of transmission to patients. JAMA 1990;264:467-470. 3. Mishu B, Griffin PM, Tauxe RV, Cameron DN, Hutcheson RH, Schaffner W. Salmonella enteritidis gastroenteritis transmitted by intact eggs: the epidemic advances. Ann Intern Med 1991;115:190-194. 4. Weber JT, Hibbs RG, Darwish A, Mishu B, Corwin AL, Rakha M, Hatheway CL, 6 Sharkawy SE, El-Rahim AS, Sheba MF, Sarn JE, Blake PA, Tauxe RV. A massive outbreak of type E botulism in Cairo, Egypt. J Infect Dis 1993;167:451-454. 5. Vugia DJ, Mishu B, Smith M, Tavris DR, Hickman-Brenner FW, Tauxe RV. Salmonella enteritidis outbreak in a restaurant chain: the continuing challenges of prevention. Epidemiol Infect 1993;110:49-61. 6. McKhann GM, Cornblath DR, Griffin JW, Ho TW, Li CY, Jiang Z, Zhaori G, Liu Y, Jou LP, Liu TC, Gao CY, Mao JY, Blaser MJ, Mishu B, Asbury AK. Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China. Ann Neurol 1993;33:333-342. 7. Mishu B, Amjad AA, Koski CL, Vriesendorp F, Cook SA, Mithen F, Blaser MJ. Serologic evidence of previous Campylobacter jejuni infection in patients with the Guillain-Barre Syndrome. Ann Intern Med 1993;118:947-953. 8. Vriesendorp FJ, Mishu B, Blaser MJ, Koski CL. Serum antibodies to GM1, Gd1b, peripheral nerve myelin, and Campylobacter jejuni in patients with Guillain-Barre syndrome and controls: correlation and prognosis. Ann Neurol 1993;34:130-135. 9. Mishu B, Blaser MJ. The role of Campylobacter jejuni infection in the initiation of Guillain-Barre Syndrome. Clin Infect Dis 1993;17:104-108. 10. Mishu B, Koehler J, Lee LA, Rodrigue D, Brenner F, Blake P, Tauxe RV. Outbreaks of Salmonella enteritidis infections in the United States, 1985-1991. J Infect Dis 1994;169:547-52. 11. Marrie TJ, Purdy RA, Johnston BL, McCormick CW, Benstead T, Ansell J, Maloney W, Allos BM, Blaser MJ. Encephalomyeloradiculopathy of infectious or parainfectious etiology - a new entity? J Infect Dis 1995;20:945-953. 12. Griffin JW, Li CY, Ho TW, Xue P, Macko C, Gao CY, Yang C, Tian M, Mishu B, Cornblath DR, McKhann GM, Asbury AK. Guillain-Barre syndrome in Northern China: the spectrum of neuropathologic changes in clinically defined cases. Brain 1995;118:577-595. 13. Ho TW, Mishu B, Li CY, Gao CY, Cornblath DR, Griffin JW, Asbury AK, Blaser MJ, McKhann GM. Guillain-Barre syndrome in northern China: relationship to Campylobacter jejuni infection and anti-glycolipid antibodies. Brain 1995;118:597-605. 14. Griffin JW, Li CY, Ho TW, Tian M, Gao CY, Xue P, Mishu B, Cornblath DR, Macko C, McKhann GM, Asbury AK. Pathology of motor-sensory axonal Guillain-Barre syndrome. Ann Neurol 1996;39:17-28. 15. Hibbs RG, Weber JT, Corwin C, Allos BM, Abd el Rehim MS, Sharkawy S, , Sarn JE, McKee KT. Experience with the use of an investigational F(ab')2 heptavalent botulism immune globulin of equine origin during an outbreak of type E botulism in Egypt. Clin Infect Dis 1996;23:337-40. 7 16. Allos BM, Gensheimer KF, Bloch AB, Horan JM, Schaffner W. Spread of tuberculosis in a small community: public health implications. Ann Intern Med 1996;125:114-117. 17. Fujimoto S, Allos BM, Patton CM, Blaser MJB. Restriction fragment length polymorphism analysis and random amplified polymorphic DNA analysis of Campylobacter jejuni strains isolated from patient with Guillain-Barre syndrome. J Infect Dis 1997;176:1105-1108. 18. Allos BM. Campylobacter jejuni infection and the Guillain-Barre syndrome. Specialist Medicine 1997;19;60-64. 19. Busby TC, Allos BM, Roberts T. Economic costs of C. jejuni -associated Guillain-Barre syndrome. J Infect Dis 1997;(Suppl 2):S192-197. 20. Allos BM. Evidence of an association between Campylobacter jejuni infection and Guillain-Barre syndrome. J Infect Dis 1997;(Suppl 2):S125-128. 21. Misawa N, Allos BM, Blaser MJ. Differentiation of Campylobacter jejuni strains of serotype O:19 from non-O:19 strains by polymerase chain reaction. J Clin Microbiol 1998;36:3567-3573. 22. Allos BM, Lippy FE, Carlsen AR, Blaser MJ. Serotype, serum resistance and 125I-C3 binding among C. jejuni strains from patients with Guillain-Barre syndrome or with uncomplicated enteritis. Emerging Infectious Diseases 1998;4:263-268. 23. Nachamkin I, Allos BM. Ho T. Campylobacter jejuni infection and the Guillain-Barre syndrome. Clinical Microbiology Reviews 1998;11:555-567. 24. Allos BM. Campylobacter jejuni infection as a cause of the Guillain-Barre syndrome. Infect Dis Clinics N America. March 1998;12:173-184. 25. Misawa N, Kawashima K, Kondo F, Allos BM, Blaser MJ. DNA diversity of the wla gene cluster among serotype HS:19 and non-HS:19 Campylobacter jejuni strains. J Endotox Research 2001;7:1-10. 26. Allos BM. Postexposure prophylaxis of healthcare personnel exposed to HIV. Current Treatment Options Infect Dis 2002;4:57-65. Chapters, Reviews, and Invited Contributions 1. Mishu B, Tauxe RV, Patton C. Clinical and epidemiologic features of non-jejuni Campylobacters. In: Nachamkin I, Blaser MJ, Tompkins LS, eds. Campylobacter jejuni -current strategy and future trends. Washington D.C., American Society of Microbiology; 1992:31-41. 2. Mishu B. Rabies: A primer for the practicing physician. Infectious Disease Newsletter 1993;12:1-4. 8 3. Dummer JS, Allos BM. Gastrointestinal infections in transplant recipients. In: Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL, eds. Infections of the Gastrointestinal Tract. New York, Raven Press; 1995:511-526. 4. Allos BM, Lastovica A, Blaser MJ. Atypical Campylobacters and related organisms. In: Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL, eds. Infections of the Gastrointestinal Tract. New York, Raven Press; 1995:849-866. 5. Mishu B, Tauxe RV, Griffin PM, Blaser MJ. Campylobacter jejuni infection and the Guillain Barre Syndrome. In: Gibbs CJ, McKhann GM, eds. New Issues in Neurosciences: Basic and Clinical Approaches. Bethesda, National Institutes of Health, 1992/1993; 268-271. 6. Allos BM, Blaser MJ. Campylobacter jejuni and the expanding spectrum of related infections. Clin Infect Dis 1995;20:1092-1101. 7. Schaffner W, Allos BM. Protecting patients when their surgeon or dentist is infected with a blood-borne virus. J Hosp Infect 1995;30(Suppl):156-162. 8. Allos BM, Blaser MJ. Potential role of lipopolysaccharides of Campylobacter jejuni in the development of Guillain-Barre syndrome. J Endotoxin Res 1995;2:237-238. 9. Busby JC, Roberts T, Allos BM. Estimated Annual Costs of Campylobacter-associated Guillain-Barre syndrome. Economic Research Services Report, United States Department of Agriculture, Washington D.C, 1997. 10. Allos BM. Campylobacter jejuni. In: Gorbach SL, Bartlett JG, Blacklow NR, eds. Infectious Diseases (second edition). Philadelphia, WB Saunders Company; 1998:726732. 11. Allos BM. Campylobacter. In: Gorbach SL, Bartlett JG, Blacklow NR, eds. Infectious Diseases (second edition). Philadelphia, WB Saunders Company; 1998:1810-1815. 12. Allos BM, Taylor DN. Campylobacter infections. In: Evans AS, Brachman PS, eds. Bacterial Infections of Humans: Epidemiology and Control. New York, Plenum Medical Book Company, 1998:169-190. 13. Allos BM, Blaser MJ. Campylobacter species. In: Yu VL, Merigan T, Barriere SL, eds. Antimicrobial Therapy and Vaccines. Baltimore, Williams and Wilkins, 1998:101-109. 14. Allos BM, Blaser MJ. Campylobacter infections in the developing world. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical Infectious Diseases. Philadelphia, Churchill Livingstone, 1999:319-325. 15. Nachamkin I, Allos BM. Ho T. Campylobacter jejuni infection and the association with Guillain-Barre syndrome. In: Nachamkin I, Blaser MJ (eds). Campylobacter (second edition). Washington DC, ASM Press, 2000: 155-175. 9 16. Allos BM. Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 2001;32:1201-1206. 17. Allos BM, Blaser MJ. Campylobacter species. In Yu, Weber, Raoult, eds. Antimicrobial Therapy and Vaccines (second edition). New York, Apple Trees Productions, LLC, 2002: 169-171. 18. Allos BM. Moore MR. Griffin PM. Tauxe RV. Surveillance for sporadic foodborne disease in the 21st century: the FoodNet perspective. Clin Infect Dis 2004;38 Suppl 3:S115-120 19 Lastovica AJ, Allos BM. Clinical significance of Campylobacter and related species other than Campylobacter jejuni and Campylobacter coli. In: Nachamkin I, Szymanski CM, Blaser MJ (eds). Campylobacter (third edition). Washington DC, ASM Press, 2008: 123-150. 20 Allos BM, Blaser MJ. Campylobacter jejuni. In: Cecils Textbook of Medicine; 23rd ed. B Saunders Co., 2008 2231-2233. 21. Allos BM, Blaser MJ. Campylobacter jejuni and related species. In: Mandell (GL), Bennett JE, Dolin R (eds) Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases., 7th ed. Philadelphia: Churchhill Livingstone; 2010; 2793-2802. 22. Allos BM. Campylobacter: clinical characteristics. In: UpToDate®, Inc. founded by Burton D. Rose, MD & Joseph M. Rush, M, 2010. 23. Allos BM. Campylobacter: microbiology and epidemiology. In: UpToDate®, Inc. founded by Burton D. Rose, MD & Joseph M. Rush, M, 2010 Editorials 1. Mishu B, Schaffner W. HIV-infected surgeons and dentists: looking back and looking forward. JAMA 1993;269:1843-1844. 2. Mishu B, Schaffner W. HIV transmission from surgeons to patients: Can models predict magnitude of risk? Infect Control Hosp Epidemiol 1994;15:144-147. 3. Mishu B, Blaser MJ. Do you have a Campylobacter in your future? West J Med 1994;161:186-187. 4. Allos BM, Blaser MJ. Campylobacter jejuni Infection and the Guillain-Barre Syndrome: Mechanisms and Implications. International Journal of Medical Microbiology, Virology, Paristology, and Infectious Diseases 1994;281:544-548. 10 5. Lang DA, Allos BM, Blaser MJ(guest editors). Development of Guillain-Barre Syndrome following Campylobacter Infection. J Infect Dis 1997;176:S91. 6. Allos BM, Schaffner. Patient to patient transmission of hepatitis B: An elephant in the room ….. or a mouse? J Infect Dis 2007;195:1311-1314 Letters and other Contributions 1. False-positive Mono-spot tests in East Tennessee. Tennessee Communicable Diseases Bulletin 1989. 2. Salmonella enteritidis infections and shell eggs - United States, 1990. MMWR 1990;39:909-12 3. Campylobacter enteritis - New Zealand 1990. Editorial Note. MMWR 1991;40:123. 4. Mishu B, Schaffner W. A surgeon with AIDS. (letter) JAMA 1991;264:3147-8. 5. Mishu B, Schaffner W. Foodborne hepatitis A and microwaves.(letter) J Infect Dis 1991;163:918. 6. Mishu B, Griffin PM, Schaffner, W. Eggs and Salmonella enteritidis transmission. (letter) Ann Intern Med 1992;116:93-94. 7. Mishu B, Griffin PM. Correction: Gastroenteritis transmitted by intact chicken eggs.(letter) Ann Intern Med 1992;116:1037. 8. Mishu B, Blaser MJ. Campylobacter jejuni infection, Guillain-Barre Syndrome and Human Immunodeficiency Virus infection. (letter) J Infect Dis 1994;169:1177. 9. Allos BM. Reply. (Letter) Clinical Infect Dis 2002;34:720-721. 11