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Transcript
Program for the Chabner Symposium, Liberty Hotel, November 5-6, 2012
(as of September 11, 2012)
November 5, 2012
(6.75 CME credits – Day 1)
7:45am
Welcome
Daniel Haber, MD, PhD
Massachusetts General Hospital Cancer Center, Harvard Medical School
1st Session:
Modifiers of Gene Expression
Convener – Daniel Haber
8:00-8:45a
Ari Melnick, MD, Center on the Microenvironment and Metastasis, Cornell University
IDH and TET 2 Mutations in Human Leukemia
8:45-9:30a
William Kaelin, MD, Dana-Farber Cancer Institute, Harvard Medical School
IDH 1 as an Oncogene
9:30-10:15a
James Bradner, MD, Dana-Farber Cancer Institute, Harvard Medical School
Bromodomain Inhibitors
10:15-10:30a
Break
2nd Session: Signaling Inhibitors: Insights into Resistance
Convener - Jeff Clark, MD
Massachusetts General Hospital Cancer Center, Harvard Medical School
11:30-11:15a
Matthew Smith, MD, PhD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
Role of VEGFR and MET in Prostate Cancer and Bone Metastases
11:15-12:00p
Jose Baselga, MD, PhD, Memorial Sloan-Kettering Cancer Center
PI3 Kinase Inhibitions in Clinical Development
12:00-1:00p
Lunch
3rd Session:
Tumor Quiescence, Drug Response in Vitro, and Drug Resistance
Convener - Donald Kufe, MD
Dana-Farber Cancer Institute, Harvard Medical School
1:00-1:45p
Sridhar Ramaswamy, MD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
Targeting Quiescent Cancer Cells
1:45-2:30p
Cyril Benes, PhD, Massachusetts General Hospital Cancer Center, Harvard Medical
School
Cell Line Screening
2:30-3:15p
Michael Birrer, MD, PhD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
Prospects for Targeted Therapy in Ovarian Cancer
3:15-3:30p
Break
3:30-4:15p
Ryan Corcoran, MD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
Resistance to RAF Inhibition in BRAF Mutant Colorectal Cancer
DF/HCC Junior Faculty Forum (non-CME)
Page 1 of 3
Program for the Chabner Symposium, Liberty Hotel, November 5-6, 2012
(as of September 11, 2012)
4:15-5:15p
David Sykes – Identifying Small Molecules that Overcome Differentiation Arrest in
Acute Myeloid Leukemia
Andrew Elia – Proteomic Approaches to Study Ubiquitination and Protein Stability
Julie Losman Rizwan Haq -
5:30 – 6:30p
Evening reception
Page 2 of 3
Program for the Chabner Symposium, Liberty Hotel, November 5-6, 2012
(as of September 11, 2012)
November 6, 2012
(3.75 CME credits – Day 2)
4th Session:
Clinical Breakthroughs
Convener: Bruce A. Chabner, MD
Massachusetts General Hospital Cancer Center, Harvard Medical School
8:00-8:45a
Alice Shaw, MD, PhD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
ROS 1 kinase, a Target for Lung Cancer
8:45-9:30a
Frank Haluska, MD, PhD, Ariad Pharmaceuticals
Development of a Novel BCR-ABL Inhibitor for CML
9:30-10:15a
Carl June, MD, University of Pennsylvania
Smart T-Cell Vaccines
10:15-10:30a
Break
10:30-11:15a
Xandra Breakefield, PhD, Massachusetts General Hospital Cancer Center, Harvard
Medical School
Exosomes as Biomarkers of the Genetic Status of Brain Tumors
11:15-12:00p
Suzanne Topalian, MD, Johns Hopkins University
AntiPD1
12:00p
Closing Remarks
Bruce Chabner
Page 3 of 3
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