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EligibilityCriteria Lastupdated:11/30/2015 Page1 Pleaserevieweacheligibilitycriteriabelow.Pleasechecktheboxifyouareincompliancewitheachcriteria. Ineligibleapplicantswillnotbereviewed. ResponsesSelected: Nomineehasmadesignificantcontributionstothefieldofsolidorgantransplantation. Nomineeisrecognizedasanexpertinhis/herfield. NomineeandnominatorareactivemembersoftheAST.Membershipduesarepaidtodate(by1/1/2015);otherwisethenominationwillbe disqualifiedandnotconsidered. 1of1 PersonalInformationForm Lastupdated:11/30/2015 PersonalInformation NomineeInformation Pleaseenterinallinformationfornominee. FirstName Jon LastName Kobashigawa Degree MD Title AssociateDirectorofClinicalAffairs Institution Cedars-Sinai Department Medicine Address 127S.SanVicenteBlvd. ThirdFloorCardiologyA3107 City LosAngeles State/Province California Zip/PostalCode 90048 Country US Phonenumber (310)248-8300 Email [email protected] NominatorInformation Pleaseenterinallinformationfornominator. FirstName Jeffrey LastName Teuteberg Degree MD Title MedicalDirector,AdvancedHeartFailurer Institution UPMC Department HeartandVascularInstitute Address ScaifeHall,Suite556 200LothropStreet City Pittsburgh State/Province Pennsylvania Zip/PostalCode 15213 Country US Phonenumber 4126477168 1of2 Email [email protected] IsthisnominationmadeonbehalfofanASTadvisorycouncil,committee,orcommunityofpractice? Yes Ifyes,pleaselistadvisorycouncil/committee/communityofpracticename: TCCCOP 2of2 7/ 27/2015 JON KOBASHIGAWA, MD Business Address: Cedars-Sinai Heart Institute 127 S. San Vicente Blvd. Third Floor Cardiology A3107 Los Angeles, CA 90048 Phone: Fax: Email: (310) 248-8300 (310) 248-8333 [email protected] E D U CA T I O N 1972 - 1976 B.S., Stanford University, Stanford, CA 1976 - 1980 M.D., Mount Sinai School of Medicine, New York, NY 1980 - 1981 Internship in Internal Medicine UCLA Medical Center, Los Angeles, CA 1981 - 1983 Residency in Internal Medicine UCLA Medical Center, Los Angeles, CA 1984 - 1986 Fellowship in Cardiology UCLA Medical Center, Los Angeles, CA A P PO I N T M E N T S 1986 - 1988 Clinical Instructor of Medicine The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA 1988 - 1994 Assistant Clinical Professor of Medicine, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA 1994 - 1999 Associate Clinical Professor of Medicine The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA 1994 - 2009 Medical Director, UCLA Heart Transplant Program UCLA Medical Center, Los Angeles, CA 1998 - 2009 Chief, Division of Clinical Faculty Medicine, Department of Medicine, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA CURRICULUM VITAE JON KOB ASHIGAWA, MD 1999 - Present Clinical Professor of Medicine The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA 1999-Present Chief Medical Officer, California Heart Center Foundation Los Angeles, CA 2005-Present Board of Directors, California Heart Center Foundation Los Angeles, CA 2003-Present President, University Cardiovascular Medical Group Los Angeles, CA 2010-Present DSL/Thomas D. Gordon Chair in Heart Transplantation Medicine Cedars-Sinai Medical Center Los Angeles, CA 2010-Present Associate Director for Clinical Affairs Director for Advanced Heart Disease Director, Heart Transplant Program Cedars-Sinai Heart Institute Los Angeles, CA 2015-Present Professor of Medicine Cedars-Sinai Medical Center Los Angeles, CA M E M BE R S H I P S Alpha Omega Alpha American Association for the Advancement of Science American College of Cardiology American College of Physicians American Heart Association American Medical Association American Society of Transplant Physicians California Medical Association Council of Clinical Cardiology (American Heart Association) International Society for Heart and Lung Transplantation Internship Selection Committee of the UCLA School of Medicine Los Angeles Medical Association Medical Staff Credentials Committee of the UCLA Hospital NIH Training Grant Cardiovascular Scientist Training Program Faculty UCLA Clinical Faculty Association UCLA Clinical Faculty Association Board of Directors UCLA Clinical Faculty Association (Vice President 1998-1999) Working Group of Transplant Cardiologists (national organization) Member, Search Committee for UCLA Chief of the Division of Cardiac Surgery 2 CURRICULUM VITAE JON KOB ASHIGAWA, MD A P PO I N T M E N T S I N NA T I O NA L CO M M I T T E E S Clinical Practice Committee, American Society of Transplant Physicians 1996-1998 Transplantation Committee, American College of Cardiology 1997-1999 Training and Manpower Committee, American Society of Transplant Physicians 1998 Practice Guidelines Committee, American Society of Transplant Physicians 1998 Board of Directors, International Society for Heart and Lung Transplantation 1997-2004 Program Chair, International Society for Heart and Lung Transplantation Scientific Sessions, Osaka, Japan 2000 President, International Society for Heart and Lung Transplantation 2003-2004 Board of Directors, American Heart Association Western States Affiliate 1998-1999 Medical Director, Gift of Heart Foundation, Los Angeles, CA 2000 At-Large Member, UNOS National Thoracic Organ Committee 2000 Clinical Cardiology Council, Scientific Council, American Heart Association 2000-2003 Chairman, Heart Failure and Transplant Committee, American College of Cardiology 2000-2004 Heart Transplant Advisory Board for CIGNA Healthcare’s Lifesource Transplant Network 2002-Present Consultant, Foundation for the Accreditation of Cellular Therapy for the Hematopoietic Stem Cell Transplantation Program 2002-Present Advisory Board, Ventura County West Valley Transplant Recipients International Organization (TRIO) April 2005 Advisory Board, MedscapeCME Transplantation 2010-2012 Member, Study Scientific Committee for RAD trial A2310, 2009-Present Invited Participant, NHLBI Workshop, “Cardiac Transplantation Research for the Next Decade: A Goal to Evidence Based Outcomes.” Bethesda, MD, 2010 American Transplant Congress Program Committee 2011-2015 Clinical Trials in Organ Transplant (CTOT) Steering Committee 2012-present Member of Executive Committee, AST Thoracic and Critical Care Community of Practice 2013-2014 Member, International Society for Heart and Lung Transplantation Education Taskforce 2013-2014 Executive Program Committee for the World Transplant Congress 2012-2014 C E RT I F I CA T I O N S / L I CE N S E S California Medical License #G45447 DEA License #AK 1274149 Diplomate American Board of Internal Medicine (September 14, 1983) Diplomate American Board of Cardiovascular Disease (November 11, 1987) Certified for Special Competency - Cardiac Pacing (NASPE) Fellow - American College of Cardiology Fellow – American Heart Association Fellow – American Society of Transplantation AWA R D S / H O N O R S Alpha Omega Alpha Honor Medical Society (September 1979) Upjohn Clinical Scholar Award (June 1980) UCLA Clinical Faculty Teaching Award (June 1987, June 1990, June 1991, June 2004) 3 CURRICULUM VITAE JON KOB ASHIGAWA, MD Member of the American College of Cardiology Task Force on Cardiac Transplantation: The 24th Bethesda Conference. Author on sections on Cardiac Rejection, Osteoporosis, Obesity, Surgical complications, and Psychosocial issues in cardiac Transplantation. Nov 1992, Bethesda, MD. Program Director: An International Symposium on Heart Failure and Heart Transplantation 1995. Lectures given: Diagnosis and treatment of rejection, Steroid-free immunosuppression, Treatment of transplant coronary artery disease. The Disneyland Hotel, Anaheim, CA, November 9-11, 1995. Plenary Session: Invited lecture, International Society for Heart and Lung Transplantation Scientific Sessions. Results of randomized trial of mycophenolate mofetil vs. azathioprine in heart transplantation. London, England, April 3, 1997. FDA Advisory Board Meeting: Use of mycophenolate mofetil for indication in heart transplantation. Washington, DC, January 14, 1998. Program Chair, International Society for Heart and Lung Transplantation Scientific Sessions, Osaka, Japan 2000 Chair, Novartis Lunch Symposium: “TCAD: IVUS, Surrogate Markers & Treatments.” International Society for Heart and Lung Transplantation, 23rd Annual Meeting and Scientific Sessions, Vienna, Austria April 7-13, 2003 President, International Society for Heart and Lung Transplantation 2003-2004 Chairman, Heart Failure and Transplant Committee, American College of Cardiology 2000-2004 At-Large Member, United Network for Organ Sharing National Thoracic Organ Committee 2000 Millennium Edition of Strathmore’s Who’s Who (2000-2001) Los Angeles Times Dr.’s Dr. Recognition in Cardiology (2000 - Present) Marquis Who’s Who in America / Medicine and Healthcare (2000 - Present) Wall Street Journal Businessman of the Year (2001) Best Doctors in America (2001 - Present) Who’s Who in the 21st Century, 1st Edition (2001) Co-Chair, Work Group Sessions: Diagnosis of Humoral Rejection. A Conference to Analyze Humoral Rejection in Solid Organ Transplantation, Bethesda, MD, April 23-24, 2003. Co-Chair: Clinical Science Symposium: Pre-Transplant Risk Factors and Effect on Post-Transplantation Outcomes. American Transplant Congress 2004 Meeting. John B. Haynes Convention Center, Boston, MA. May 17, 2004. United States National Leader, AQUARIUS Trial (2009) Chairman, An International Consensus Conference on the Sensitized Patient Awaiting Heart Transplantation. California Heart Center Foundation and the International Society for Heart and Lung Transplantation. Boston, MA, April 8, 2008 Invited Keynote Speaker, The 6th Biennial Psychiatric, Psychosocial and Ethical Issues in Organ Transplantation Conference. Keynote Address: Cardiac Transplantation: Advances and Ethical Dilemmas. Doubletree Hotel, Santa Monica, CA. February 4-6, 2005. Pfizer Visiting Professorship, Northwestern University Cardiology Grand Rounds: “Advances in Immunossuppression in Heart Transplantation.” Northwestern University Feinberg School of Medicine, Chicago, IL, September 14-15, 2006. Discussant, Late-Breaking Clinical Trials II: CORONA trial. American Heart Association Scientific Sessions 2007, Orlando, FL, November 5, 2007. 4 CURRICULUM VITAE JON KOB ASHIGAWA, MD Cambridge Who’s Who Among Executives and Professionals in Healthcare, Honors Edition (2007-2008) Co-chairman, 72nd Annual Scientific Meeting of the Japanese Circulation Society. Lecture given: “Current Status in Cardiac Transplantation in the United States.” Fukuoka, Japan, March 28, 2008. Distinguished Service Award from the California Heart Center Foundation (2009) International Association of Cardiologists’ Top Cardiologist (2009-2010) Invited Participant, NHLBI Workshop, “Cardiac Transplantation Research for the Next Decade: A Goal to Evidence Based Outcomes.” Bethesda, MD, August 5-6, 2010. Member of the Clinical Trials in Organ Transplantation (CTOT) steering committee (2011-present) Member of the Novartis Data Safety Monitoring Board, CRAD001A2429 Trial (2011-present) Reviewer for the Health Research Council of New Zealand 2011 Annual Contestable Funding Round Reviewer for the Medical Research Council Industrial Collaboration Award (September 2011) Director of RAD-B253 8-Year Follow Up Investigator’s Meeting Prague, Czech Republic. April 17, 2012. Member of Special Review Committee for Program Project Grant Application (NIH/NHLBI): Cardiac allograft tolerance through kidney co-transplantation, P01HL116266-01. May 9, 2012. Reviewer for Heart Research United Kingdom Translational Research Project Grant, UK national charity (2012) Visiting Lecturer for the Servier Canada Endowed Lectureship in Heart Function, University of Ottawa Heart Institute, November 18-19, 2012. Invited Ad Hoc Reviewer for NIH Program Grant: Cardiac allograft tolerance through kidney co-transplantation, 1 P01HL116266-01. February 18, 2013. Course Co-Director of the 24th Annual Meeting of the California ACC: Controversies & Advances in the Treatment of Cardiovascular Disease. November 21 & 22, 2013. Executive Program Committee for the World Transplant Congress 2012-2014 Featured Guest, Heart to Heart Community Conversation with Larry Mantle, SLS Hotel, Los Angeles, California, February 25, 2014 Top Doctors in L.A., The Hollywood Reporter, September 2014. Visiting Professorship, Queens Hospital, Honolulu, Hawaii. October 10, 2014. Member of the Transmedics the PROCEED II Trial Steering Committee (2011-2013). Member of the Organ Care System EXPAND Heart Steering Committee (2014-present) Visiting Professorship, Cleveland Clinic, Philadelphia, Pennsylvania May 7th, 2014. Chairman of the Outcomes AlloMap Registry and Diagnostic and Prognostic Utility of Cell-free DNA in association with Gene-Expression Profiling (AlloMap®) in Heart Transplant Recipients Steering Committee (August 2015). E D I TO R I A L BOA R D S Editorial Board, Cardiology Today (1998 - present) Associate Editor, American Society of Transplantation Primer for Heart Transplantation (1999) Guest Editor, Heart Transplant Section in Graft, AST Winter Symposium (1999) 5 CURRICULUM VITAE JON KOB ASHIGAWA, MD Editorial Board, Journal of Heart and Lung Transplantation (1999-present) Associate Editor, American Journal of Transplantation (2000-2002) Editorial Board, the heart.org for Heart Failure & Cardiac Transplant Medicine (2000-present) Editorial Board, Medscape Transplantation (2000-present) Associate Editor, AST Newsletter (2000) Editorial Board, Journal of Cardiac Failure (2002) Editorial Board, Reviews on Clinical Transplantation (2006-Present) Editorial Board, Trends in Transplantation (2007, 2011) Senior Consultant, Editorial Board, Journal of Heart & Lung Transplantation (2009) International Editorial Board, European Heart Journal (2012) Section Editor, Thoracic Transplantation, Current Transplantation Reports (2013) Guest Editor, Thoracic Transplantation, Current Transplantation Reports (2015) A B S T R A CT G R A D E R Scientific Sessions of the American College of Cardiology 1989, 1990, 2001, 2006, 2007. Scientific Sessions of the American Heart Association 1994. Scientific Sessions of the International Society of Heart and Lung Transplantation 1995-2003, 2005, 2006, 2008, 2009, 2010, 2011 Co-Chairman, Clinical Heart Transplant Section, ISHLT Program Committee 1995. Program Chairman, ISHLT Scientific Sessions in Osaka, Japan 2000. Scientific Sessions of the American Society of Transplant Physicians 1996, 1999, 2001, 2002, 2003, 2006, 2007. Joint American Transplant Meeting 2001. Co-Chairman, Immunosuppression Section, ISHLT Program Committee 2001. Co-Chairman, Thoracic Organ Transplant Section, International Symposium on Immunosuppression, San Diego, CA. 2001 and 2004. Co-Chairman, Clinical Heart Section, American Transplant Congress, Seattle, WA. 2005. World Transplant Congress 2006. American Transplant Congress 2007, 2008, 2009, 2010, 2011 Abstract Panel Review International Congress of the Transplantation Society 2008, 2009, 2010 American College of Cardiology Abstract Reviewer 2015 S TA N D I N G M A N U S CR I P T R E V I E W E R American Journal of Cardiology American Journal of Kidney Diseases American Journal of Transplantation Annals of Transplantation Atherosclerosis Collegium Antropologicum European Heart Journal Expert Opinion On Drug Safety Circulation Circulation: Heart Failure Circulation: Research Clinical Transplantation Future of Medicine 6 CURRICULUM VITAE JON KOB ASHIGAWA, MD Human Immunology International Journal of Cardiology Journal of Heart and Lung Transplantation Journal of the American College of Cardiology Journal of the American College of Cardiology: Heart Failure Nature Reviews Cardiology New England Journal of Medicine Pediatric Transplantation Science Translational Medicine Therapeutic Advances in Cardiovascular Disease Translational Research Transplantation Transplant Immunology Transplant International World Journal of Surgery P R E S E N TA T IO N S / S Y MP O S I U M S American Heart Association, Los Angeles Chapter. Luncheon panel on: Cardiac Transplantation. October 1989. Heart Failure and Transplantation: 1990. (January 19-20, Doubletree Marina Beach Hotel, Marina del Rey, California). Sponsor, UCLA School of Medicine. Lectures given: Selection for heart Transplantation, diagnosis and treatment of rejection, accelerated atherosclerosis and other late complications. Panel discussant on How to manage immunosuppression. Family Practice Refresher Course: Treatment strategies in congestive heart failure. May 28, 1991. Sponsored by the UCLA Extension, Division of Family Medicine UCLA School of Medicine, Family Practice residency program at Santa Monica Hospital Medical Center. Current Concepts in Cardiovascular Disease: Managing the mature and elderly patient. September 21, 1991. Sponsored by UCLA Extension. Lecture given: Diagnosis and management of hypertensive urgencies and emergencies. Family Medicine Grand Rounds: Modem therapy of congestive heart failure. October 18, 1991. Symposium on Transplant Coronary Artery Disease and Steroid Weaning. Guest speaker on: Weaning of steroid maintenance late after cardiac Transplantation, relation to HLA-DR matching. St. Louis, MO, October 25, 1991. Sponsored by International Society for Heart and Lung Transplantation. Symposium: Current Controversies in Cardiac Transplantation - Panel Speaker. International Society for Heart and Lung Transplantation Scientific Sessions. April 1, 1992 in San Diego, CA. Family Medicine Refresher Course. Lectures given: Approach to the patient with syncope; Clinical approach to hypertensive urgency/emergency. May 28, 1992. Medical Grand Rounds: Recent advances in the treatment of congestive heart failure. Hollywood Community Hospital, August 21, 1992. Medicine Staff Rounds: -Congestive heart failure. Monrovia Community Hospital. September 17, 1992. Medicine Grand Rounds: Cardiac Transplantation. Wadsworth VA Medical Center. October 14, 1992. Medicine Staff Rounds: Current evaluation and management of cardiac failure, including cardiac Transplantation. Temple Community Hospital, October 27, 1992. Member of the American College of Cardiology Task Force on Cardiac Transplantation: The 24th Bethesda Conference. Author on sections on Cardiac Rejection, Osteoporosis, Obesity, Surgical complications, and Psychosocial issues in cardiac transplantation. Nov 1992, Bethesda, MD. 7 CURRICULUM VITAE JON KOB ASHIGAWA, MD Heart transplant monitor expert panel, sponsored by Medtronics. Westin La Paloma Resort.Tucson, AZ. Dec l013, 1992 Heart Failure and Heart & Lung Transplantation. 1993. January 7-9, 1993, Ritz Carlton Hotel, Marina Del Rey, CA. Lectures given: Contraindications to cardiac transplantation, Diagnosis and treatment of rejection, New immunosuppressive therapies, Accelerated graft atherosclerosis. Panel discussant on medical management after transplantation. Moderator: Post transplant complications. Transplant Recipients International Organization (TRIO). immunosuppressive therapies. January 11, 1993. Lecture on heart transplant rejection and new Regional Transplant Coordinators Meeting. Lecture on mycophenolate mofetil in cardiac transplantation. Loews Hotel, Santa Monica, CA. February 17, 1993. Sandoz Sponsored Cardiac Transplant Expert Panel on cyclosporine dosing, steroid-free immunosuppression, transplant coronary artery disease and long-term renal function. Boca Raton, FL. March 29,30, 1993. Symposium: Recent Advances in Cardiology. Lecture on frontiers in cardiac transplantation. Sponsored by Western Medical Center. Anaheim Marriott, May 1, 1993. Cardiology Rounds Lecture on: Heart Transplantation. Sierra Vista Regional Medical Center. San Luis Obispo, CA. June 2, 1993 Family Practice Refresher Course: Treatment of congestive heart failure. Approach to the patient with syncope. Miramar Sheraton Hotel. Santa Monica, CA. June 3, 1993. Heart and Lung Transplantation. Delta Medical Center, Visalia, CA. September 7, 1993. The use of pravastatin in heart transplant recipients. Division of Adult Cardiology monthly conference. UCLA Medical Center. October 26, 1993. Selected Topics in Cardiology. Family Medicine Symposium: Approach to the patient with chest pain. Sheraton Miramar Hotel, Santa Monica, CA. October 30, 1993. Heart Transplantation. Henry Mayo Newhall Memorial Hospital. Valencia, CA. November 4, 1993. ROPA Donor Presentation. Holy Cross Medical Center, Mission Hills, CA. November 17, 1993. Pravastatin in Heart Transplantation. Lipid Education Faculty Program, Pazzia Restaurant, Los Angeles, CA. Sponsored by E.R. Squibb. November 18, 1993. Southern California Lipid Conference. Pravastatin in cardiac transplant atherosclerosis. Hyatt Newport, Newport Beach, CA. November 20, 1993. Sponsored by Bristol Myers Squibb. Cardiology Rounds: Advances in Heart Transplantation. Queen of the Valley Medical Center, West Covina, CA. February 8, 1994. Medicine Grand Rounds: Care of the Heart Transplant Recipient. Daniel Freeman Memorial Hospital, Los Angeles, CA. February 10, 1994 Overview of Heart Transplantation. Thousand Oaks Rotary Club, Howard Johnson Hotel, Thousand Oaks, CA. February 17, 1994. Invited speaker: Natural History of Grade 1 B, 2 and 3A Rejection Symposium. Doubletree Hotel Post Oak, Houston, TX. February 26, 1994. Texas Heart Institute. Medicine Grand Rounds: Update in heart transplantation. Kaiser West Los Angeles Medical Center. Los Angeles, CA, March 1, 1994. 8 CURRICULUM VITAE JON KOB ASHIGAWA, MD Moderator, International Society Heart and Lung Transplantation Scientific Sessions, March 26, 1994, Venice, Italy. Cardiothoracic Surgery Grand Rounds: Impact of pravastatin in heart transplant recipients. UCLA Medical Center, March 29, 1994. Invited Speaker: HMG CoA reductase inhibitors and immunosuppressive agents. Issues in lipid education in the 1990s: Therapeutic considerations. April 8 & 9, 1994, Orlando, Florida. UCLA Division of Cardiology Seminar: Advances in cardiac transplantation. UCLA Medical Center, May 13, 1994. Medicine Grand Rounds: Impact of pravastatin in cardiac transplantation. UCLA Medical Center, May 18, 1994. Invited Speaker, Cardiology Rounds: Research in cardiac transplantation. Barnes Hospital, Washington University School of Medicine, St. Louis, Mo., May 27, 1994. Family Practice Refresher Course: Approach to the patient with congestive heart failure. Miramar Sheraton Hotel. Santa Monica, CA. June 2, 1994. Endocrine Grand Rounds: The treatment of hyperlipidemia in solid organ transplantation. Wadsworth VA Medical Center, Los Angeles, CA. June 3, 1994, American College of Physicians, Internal Medicine Board Review Faculty, UCLA School of Medicine. Lecture: Preoperative evaluation, prophylaxis, and imaging. July 10, 1994, Los Angeles, CA. Invited Speaker, Cardiology Grand Rounds: Early hospital discharge, working with managed care. July 25, 1994, Texas Heart Institute, Houston, TX. Medicine Grand Rounds: Heart Transplantation. Torrance, CA. September 7, 1994, Torrance Memorial Medical Center, Invited Speaker for the integrated West Los Angeles VAMC / San Fernando Valley Cardiology Program: Heart Transplantation. September 12, 1994. Invited Speaker, Medicine Grand Rounds: Cardiac Transplantation. Kaiser-Permanente Medical Center, Los Angeles, CA, September 22, 1994. Invited Speaker, Medicine Grand Rounds: Lipid Disorders in Heart Transplantation. Ochsner Clinic, New Orleans, LA, November 2, 1994. Invited Speaker, Lipid Research Faculty Symposium: Treatment of hyperlipidemia in high risk populations, Anthony Gotto, MD, Chairman. Dallas, TX, November 12, 1994. Moderator: Cardiac Transplant Coronary Artery Disease Section. American Heart Association Scientific Sessions, Dallas, TX, November 14, 1994. Chairman, Symposium: Hyperlipidemia and Atherosclerosis in Organ Transplantation: Can We Alter the Natural History? Dallas, TX, December 8, 1994. UCLA Sports Medicine Conference: Management of Syncope in the Athlete. Division of Family Medicine. UCLA Medical Center, Los Angeles, CA. January 18, 1995. Invited Speaker, Medicine Grand Rounds: Immunosuppressive effects of hypolipidemic therapy in Heart Transplantation. St Paul's Medical Center - University of Texas Southwestern, Dallas, TX, January 20, 1995. UCLA Division of Cardiology Seminar: Update in heart transplantation. UCLA Medical Center, Los Angeles, CA, January 27, 1995. 9 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Second Symposium on Cardiac Allograft Vasculopathy. Lectures on "Does rejection correlate with development of ACAD: Results of a multicenter study using ICUS", "Use of bypassed donor hearts", and "Impact of lipid lowering therapy on ACAD". Ritz-Carlton Hotel, St. Louis, MO., January 31 - February 1, 1995. UCLA Cardiothoracic Grand Rounds: Advances in cardiac transplantation. CA, February 14, 1995. UCLA Medical Center, Los Angeles, Symposium - Lung Transplantation: An International Dialogue. Lecture on "Immunosuppression: Current Protocols, What’s Ahead?" Ritz-Carlton Hotel, Laguna Niguel, CA, February 17, 1995. Invited Speaker: Update on heart transplantation- Saint Joseph Medical Center, Burbank, CA, February 23, 1995. Invited Speaker: Optimal immunosuppression in heart transplantation. Texas Heart Institute Symposium, Double Tree Hotel, Houston TX, February 25, 1995. UCLA Medicine Grand Rounds: Advances in Cardiac Transplantation- UCLA Medical Center / School of Medicine, Los Angeles, CA, March 3, 1995. Invited Speaker. Lipid Research Faculty Symposium: Hyperlipidemia in organ transplantation. Anthony Gotto, MD, Chairman. New Orleans, LA, March 18, 1995. Invited Speaker: Management of hyperlipidemia. Stouffer Hotel, Los Angeles, CA, March 26, 1995. Case Presentations: Heart Transplantation. Invited Speaker/Discussant. International Society for Heart and Lung Transplantation Scientific Sessions, San Francisco, CA, April 5, 1995. Moderator: Clinical Heart Transplantation: Outcome and risk factors. International Society for Heart and Lung Transplantation Scientific Sessions, San Francisco, CA, April 5, 1995. Invited Speaker: Modern therapy for congestive heart failure. Little Company of Mary Hospital, Torrance, CA, April 27, 1995. Invited Speaker: Hyperlipidemia in solid organ transplantation. Loma Linda Medical Center, Loma Linda, CA, May 8, 1995. UCLA Family Medicine Refresher Course. Lecture: Medical versus surgical management of coronary artery disease. Miramar Sheraton Hotel, Santa Monica, CA, June 1, 1995. Invited Speaker, Medicine Grand Rounds: Cardiac transplantation. Kaiser Regional Medical Center, Los Angeles, CA, June 23, 1995. Invited Speaker, UCLA Family Medicine Grand Rounds: Medical versus surgical treatment of coronary artery disease. UCLA Medical Center, Los Angeles, CA, June 29, 1995. American College of Physicians, Internal Medicine Board Review Faculty, UCLA School of Medicine. Lecture: Preoperative evaluation, prophylaxis, and imaging. July 16, 1995, Los Angeles, CA. Invited Speaker, Medicine Grand Rounds: Cardiac Transplantation. Kaiser Permanente Regional Medical Center, Los Angeles, CA, August 8, 1995. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. University of Minnesota, Minneapolis, MN, September 19, 1995. Invited Speaker, Transplant Grand Rounds: Hyperlipidemia and atherosclerosis in organ transplantation: Can we alter the natural history? Mayo Clinic, Rochester, MN, September 19, 1995. Invited Speaker, Association of Clinical Scientists: Applied seminar and workshop on immunologic techniques for diagnosis, transplantation and therapy. Effects of pravastatin on rejection, survival, and transplant coronary vasculopathy. Holiday Inn Crown Plaza, Redondo Beach, CA, October 26, 1995. Invited Speaker, American Heart Association Scientific Sessions 1995, Council on Clinical Cardiology: Hyperlipidemia in cardiac transplantation. Anaheim Hilton Hotel, CA, November 13, 1995. 10 CURRICULUM VITAE JON KOB ASHIGAWA, MD Program Director: An International Symposium on Heart Failure and Heart Transplantation 1995. Lectures given: Diagnosis and treatment of rejection, Steroid-free immunosuppression, Treatment of transplant coronary artery disease. CME, UCLA School of Medicine, Los Angeles, CA. The Disneyland Hotel, Anaheim, CA, November 911, 1995. Invited Speaker, Australian Satellite Symposium - Hyperlipidemia in heart transplantation. December 1, 1995 from LA9 Studios, Los Angeles, CA. UCLA General Surgery Conference: The perioperative management of cardiac disease. UCLA Medical Center, Los Angeles, CA, December 9, 1995. Invited Speaker, Medicine Grand Rounds: Hyperlipidemia and atherosclerosis in heart transplantation. Wadsworth VA Regional Medical Center, Los Angeles, CA, December 13, 1995. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia in cardiac transplantation. Medical Center, St. Louis, MO, December 19, 1995. St Louis University Invited Speaker, Medicine Grand Rounds: Hyperlipidemia in the general population and in organ transplantation. Christ Hospital, Oaklawn, IL, January 25, 1996. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia and atherosclerosis in solid organ transplantation. Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, January 25, 1996. UCLA Medical Residents Conference: The diagnosis and treatment of Syncope. UCLA Medical Center, Los Angeles, Ca, January 19, 1996. UCLA Medicine Grand Rounds: Hyperlipidemia in solid organ transplantation, can we alter the natural history? UCLA Medical Center, Los Angeles, Ca, January 31, 1996. Invited Speaker, Scientific Conference on Exercise Testing and Training in Patients With Left Ventricular Dysfunction and After Cardiac Transplantation (American Heart Association): Pathophysiology of the transplanted heart and its influence on exercise tolerance. Belleview Mido Resort Hotel, Clearwater, Florida, February 16, 1996. Invited Speaker. Lipid Research Faculty Symposium: Hyperlipidemia in organ transplantation. Anthony Gotto, MD, Chairman. Scottsdale, Arizona, February 24, 1996. Invited Speaker, Medicine Noon Conference: Hyperlipidemia and atherosclerosis after organ transplantation. Cedars-Sinai Medical Center, Los Angeles, Ca, March 7, 1996. Member on Expert Panel on Recurrent Rejection, Breakfast Symposia at the International Society of Heart and Lung Transplantation Scientific Sessions. New York City, New York, March 17, 1996. Moderator, Clinical Heart Transplantation. International Society of Heart and Lung transplantation Scientific Sessions. New York City, New York, March 18, 1996. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. Mount Sinai School of Medicine, New York City, New York, March 19, 1996. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia in solid organ transplantation. California at San Diego, San Diego, CA, March 20, 1996. University of Invited Speaker, Follow-up care of the heart transplant recipient. Cardiology Directors Annual Meeting at the American College of Cardiology Scientific Sessions, Orlando, Florida, March 24, 1996. Invited Speaker and Moderator, The Pd-Med Conference (Harvard Medical School and UCLA School of Medicine): Cardiology for primary care clinicians - Management of congestive heart failure. Long Beach Convention Center, Long Beach, CA, March 30, 1996. Invited Speaker, Cardiology Rounds: The use of pravastatin in post cardiac transplant patients. St. Michael's Hospital, Toronto, Canada, April 15, 1996. 11 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Cardiology Rounds: Pravastatin benefits in heart transplantation. Toronto General Hospital, Toronto, Canada, April 15, 1996. Invited Speaker, Dinner Symposium (The Granite Club): Cardiac transplantation. West Hill Country Club, Toronto, Canada, April 15, 1996. Invited Speaker, Medicine Grand Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. NotreDame's Hospital, Montreal, Canada, April 16, 1996. Invited Speaker, Cardiology Transplant Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. Ottawa Heart Institute, Ottawa, Canada, April 16, 1996. Invited Speaker, Cardiology Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. The St. Luc's Hospital, Montreal, Canada, April 17, 1996. Invited Speaker, Cardiology Transplant Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. Montreal Heart Institute, Montreal, Canada, April 17, 1996. Invited Speaker, Transplantation Grand Rounds: Hyperlipidemia and atherosclerosis in organ transplantation. Oregon Health Sciences University, Portland, OR, April 25, 1996. Invited Speaker, Medicine CME: Advanced heart failure: Medical therapy, devices, surgery. Holy Cross Medical Center, Mission Hills, CA, April 30, 1996. Invited Speaker, Transplant Forum and Clinical Research Conference: Hyperlipidemia and vasculopathy in solid organ transplantation; HMG's and adjunctive therapy with immunosuppressive drugs. Stanford University, Stanford, CA, May 9, 1996. Invited Speaker, UCLA Family Practice Refresher Course: Current concepts in the management of congestive heart failure. Miramar Sheraton Hotel, Santa Monica, CA, May 30, 1996. Invited Speaker, Specialty Laboratories, Inc: Hyperlipidemia and atherosclerosis in solid organ transplantation. Santa Monica, CA, June 27, 1996. Invited Speaker, American Society of Transplant Physicians - Fellows Symposium: Transplant coronary artery disease. Ritz-Carlton Hotel, St. Louis, MO, July 28, 1996. Invited Speaker, Lipid Conference: Hyperlipidemia in solid organ transplantation. University of Iowa, October 16, 1996. Invited Speaker, Symposium. Individualizing immunosuppression: Strategies for the next decade. Lectures on Treatment of asymptomatic cardiac rejection “and Non-alloimmune factors in the treatment of transplant vasculopathy" Tucson, AZ, October 25-26, 1996. Invited Speaker, Working group of transplant cardiologist. Panel reactive antibodies and cardiac transplantation. Ochsner Medical Center, New Orleans, LA, November 9, 1996. Invited Speaker, American Heart Association Scientific Sessions: transplantation. New Orleans, LA, November 10, 1996. Accelerated atherosclerosis in cardiac Invited Speaker, Cardiology Grand Rounds, Harbor-UCLA Medical Center. Update in cardiac transplantation. Torrance, CA, December 20, 1996. Invited Speaker, American Society of Transplant Physicians' Winter Symposium. Management of post-transplant lipid disorders: Impact on graft outcome. The Pointe Hilton Resort, Phoenix, AZ, February 15, 1997. Invited Speaker, Texas Heart Institute Symposium. Houston, TX, March 1. 1997. Pravastatin and the future in cardiac transplantation. Invited Speaker, American College of Cardiology Scientific Sessions: transplantation. Anaheim, CA, March 18, 1997. 12 New developments in cardiac CURRICULUM VITAE JON KOB ASHIGAWA, MD Plenary Session: Invited lecture, International Society for Heart and Lung Transplantation Scientific Sessions. Results of randomized trial of mycophenolate mofetil vs. azathioprine in heart transplantation. London, England, April 3, 1997. Moderator, Clinical heart transplantation: Allograft vasculopathy - predictors and risk factors. International Society Heart and Lung Transplantation Scientific Sessions, London, England, April 3, 1997. Moderator, Roche Luncheon Symposium on Mycophenolate Mofetil. International Society Heart and Lung Transplantation Scientific Sessions, London, England, April 3, 1997. UCLA Medicine Grand Rounds: The results of the Mycophenolate Mofetil study and other advances in cardiac transplantation. UCLA Medical Center and School of Medicine, Los Angeles, CA, May 7, 1997. Family Practice Refresher Course: Medical versus surgical approach to the patient with coronary artery disease. Miramar Sheraton Hotel, Santa Monica, CA, May 29, 1997. Invited Speaker, Endocrine Grand Rounds: Hyperlipidemia in solid organ transplantation. Cedars-Sinai Medical Center, Los Angeles, CA, June 2, 1997 Invited Speaker, Family Medicine Medical Rounds: Management of congestive heart failure. UCLA Medical Center, Los Angeles, CA, July 2, 1997. Invited Speaker, Medicine Grand Rounds: Current management of congestive heart failure. Sherman Oaks Medical Center, Sherman Oaks, CA, August 14, 1997. Invited Speaker, Surgical Teaching Rounds: Perioperative arrhythmias and heart failure. UCLA Medical Center, Los Angeles, CA, September 13, 1997. Invited Speaker, Hyperlipidemia in organ transplantation. September 24, 1997. Balboa Naval Medical Center, San Diego, CA, Invited Speaker, Family Medicine Grand Rounds: Congestive heart failure. UCLA Medical Center, Los Angeles, CA, October 3, 1997. Invited Speaker, Cardiothoracic Surgery Grand Rounds: Advances in Immunosuppression. UCLA Medical Center, Los Angeles, CA, October 7, 1997. Program Co-Chair, Advanced Heart Failure and Transplantation for the Primary Care Physician. Lecture given: Medical management of the post transplant patient: what the primary care physician needs to know. Miramar Sheraton, Santa Monica, CA, October 18, 1997. Invited Speaker, Transplantation Grand Rounds: Pravastatin in heart transplantation. University of Minnesota Medical Center, Minneapolis, MN, October 24, 1997. Chairperson, Bristol-Myers Squibb Symposium: Advanced Heart Failure and Transplantation. Cardiovascular Medical Group/UCLA Medical Center, Los Angeles, CA, November 6, 1997. University Invited Speaker, Transplant Grand Rounds: Results of MMF in heart transplantation. Stanford University, Palo Alto, CA, December 4, 1997. Invited Speaker, Cardiology Research Rounds: Update on statins in transplant coronary artery disease, Stanford University, Palo Alto, CA December 4, 1997. Invited Speaker, International Congress on Immunosuppression. Tacrolimus versus cyclosporine. The argument in favor of cyclosporine. Renaissance Resort Hotel, Orlando, FL, December 12, 1997. FDA Advisory Board Meeting: Use of mycophenolate mofetil for indication in heart transplantation. Medical Consultant on behalf of Roche Pharmaceuticals. Washington, DC, January 14, 1998. Invited Speaker, Cardiology Grand Rounds: Hyperlipidemia in heart transplantation. University of Washington Medical Center, Seattle, WA, January 23, 1998. 13 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker: Cardiac transplantation and the medical management of the post transplant patient. Holiday Inn, Bakersfield, CA, March 6, 1998. Invited Speaker, National Association of Transplant Coordinators: Use of the alternate waiting list for organ transplantation. Hilton Hotel, La Jolla, CA, March 12, 1998. Invited Speaker, Medicine Grand Rounds: Treatment of hyperlipidemia, St. Bernadine Medical Center, San Bernardino, CA, March 19, 1998. Invited Guest, Radio Talk Show “Partners In Health”: Cardiac transplantation. San Luis Obispo, CA, March 27, 1998. Invited Speaker, American College of Cardiology Symposium: Prevention of nonimmune factors. Georgia World Congress Center, Atlanta, GA, April 1, 1998. Invited Speaker, UCLA Cardiology Update: Treatment of hyperlipidemia and medical versus surgical treatment of coronary artery disease. Flamingo Hilton Hotel, Las Vegas, NV, April 3, 1998. Invited Speaker, Opening Plenary Session: Management of the highly sensitized patient pretransplant. International Society for Heart and Lung Transplantation Scientific Sessions, Sheraton Chicago Hotel, Chicago, IL, April 16, 1998. Chairman, Breakfast Symposium: Difficult heart transplant cases. International Society for Heart and Lung Transplantation Scientific Sessions, Sheraton Chicago Hotel, Chicago, IL, April 17, 1998. Invited Speaker, Luncheon workshop: Use of plasmapheresis for the sensitized VAD patient awaiting heart transplantation. International Society for Heart and Lung Transplantation Scientific Sessions, Sheraton Chicago Hotel, Chicago, IL, April 17, 1998. Invited Speaker, Breakfast symposium: When to substitute mycophenolate. International Society for Heart and Lung Transplantation Scientific Sessions, Sheraton Chicago Hotel, Chicago, IL, April 18, 1998. Moderator: In vitro and in vivo mechanisms of immunosuppression. International Society for Heart and Lung Transplantation Scientific Sessions, Sheraton Chicago Hotel, Chicago, IL, April 18, 1998. Invited Speaker, Cardiology Grand Rounds. Advances in heart transplantation. Harbor General-UCLA Medical Center, Los Angeles, CA, April 28, 1998. Invited Speaker for Family Medicine Refresher Course. Medical versus surgical approach to the patient with coronary artery disease. Miramar Sheraton Hotel, Santa Monica, CA. May 28, 1998. Invited Speaker, Cardiology Grand Rounds: Heart transplantation. UCLA Medical Center, Los Angeles, CA May 29, 1998. Invited Speaker, Division of Family Medicine, Advances in Congestive Heart Failure. UCLA Medical Center, Los Angeles, CA, July 7, 1998. Program Director, Advanced Heart Failure and Heart Transplantation for Roche Representatives. UCLA Medical Center. 100 Medical Plaza Building, Los Angeles, CA, August 6, 1998. Lectures: Overview of heart transplantation; Mycophenolate mofetil in heart transplantation, newer immunosuppressive agents. Invited Speaker, UCLA Department of Medicine Grand Rounds: Heart transplants in the next millennium. UCLA Medical Center, Los Angeles, CA, August 19, 1998. Invited Speaker, Family Medicine Grand Rounds. Medical versus surgical management of patients with coronary artery disease. UCLA Medical Center, Los Angeles, CA, August 28, 1998. Invited Speaker, Department of Surgery House Staff Rounds: Perioperative cardiac complications of arrhythmia, myocardial infarction, and congestive heart failure. UCLA Medical Center, Los Angeles, CA August 29, 1998. 14 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Symposium on transplant vasculopathy in heart transplantation sponsored by the International Society of Heart and Lung Transplantation. Lectures on the use of HMG-CoA reductase inhibitors in transplantation; vascular remodeling of transplant coronary arteries. Sheraton Hotel, Washington DC, September 25, 1998. Invited Speaker for Plenary talk on the postoperative management of transplant recipients. Japan Society for Transplantation. Kokeio Plaza Hotel, Tokyo, Japan. December 1, 1998. Invited Speaker, Luncheon Symposium. Hyperlipidemia in Heart Transplantation. Sponsored by Novartis at the Japan Society for Transplantation. Kokeio Plaza Hotel, Tokyo, Japan. Dec. 1, 1998. Invited Speaker, Cardiac transplantation module. Lecture on cardiac transplantation for second year medical students. UCLA Medical Center, Los Angeles, CA, January 4, 1999. Program Director, UCLA Symposium: Heart Failure and Transplantation: New Concepts and Therapies. Lectures given: Post transplant management, Advances in immunosuppressive therapy. Sheraton Miramar Hotel, Santa Monica, CA, January 16, 1999. Invited speaker, Cardiology Grand Rounds. Advances in Immunosuppression in Cardiac Transplantation. Sharp Memorial Hospital, San Diego, CA, January 22, 1999. Invited Speaker, Medicine Grand Rounds. HMG-CoA Reductase Inhibitors in Transplantation: Clinical to Basic Science Research. Ochsner Medical Center, New Orleans, LA, March 10, 1999. Invited Speaker, Pri-Med Conference. Debate: Statin Treatment for Normal Cholesterol Values – CON. Long Beach, CA, April 9, 1999. Invited Speaker, Sunrise Symposium. Advances in Immunosuppression: Mycophenolate and Beyond. American Society of Transplantation, Hilton Hotel, Chicago, IL, May 16, 1999 Moderator, Luncheon Session. Coronary Artery Disease in the Transplant Population. American Society of Transplantation, Hilton Hotel, Chicago, IL, May 18, 1999 Invited Speaker, Medicine Grand Rounds. The Use of HMG Reductase Inhibitors in Clinical Heart Transplantation. University of Minnesota, Minneapolis, MN, May 20, 1999. Invited Speaker, Family Medicine Refresher Course. Medical Versus Surgical Management of the Patient with Coronary Artery Disease. Sheraton Miramar Hotel, Santa Monica, CA, May 27, 1999. Invited Speaker, Cardiology Grand Rounds. Advances in Heart Transplantation and the Denervated Heart. UCLA Medical Center, Los Angeles, CA, May 28, 1999. Program Director, UCLA Symposium: Heart Failure and Transplantation: New Concepts and Therapies. Lectures given: Post transplant management, Advances in immunosuppressive therapy. Hyatt Newport, Newport Beach, CA, October 16, 1999. Invited Speaker, “Reducing Cardiovascular Risk in the New Millennium: One Heart at a Time” Staples Center, Los Angeles, CA, January 7, 2000. Invited Speaker, Grand Rounds. Novel Risk Markers for Cardiovascular Disease. Huntington Memorial Hospital (Braun Auditorium), Pasadena, CA, Friday, February 25, 2000. Invited Speaker, American College of Cardiology Scientific Sessions. Symposium: Transplant Vasculopathy: Etiologic Factors and Prevention. Anaheim Convention Center, Anaheim, CA, March 13, 2000. Invited Speaker, International Society for Heart and Lung Transplantation. Satellite Symposium 1: Introduction to Clinical Heart Transplantation: Pre-Operative Issues. “Physiology of the Transplanted Heart and Pacing Needs Convention Hall,” Osaka International Convention Center, Osaka, Japan, April 5, 2000. 15 CURRICULUM VITAE JON KOB ASHIGAWA, MD Moderator, International Society for Heart and Lung Transplantation Opening Plenary Session. Convention Hall, Osaka International Convention Cent er, Osaka, Japan, Thursday, April 6, 2000. Invited Speaker, International Society for Heart and Lung Transplantation Plenary Session. Scientific Program Report, Convention Hall, Osaka International Convention Center, Osaka, Japan, Thursday, April 6, 2000. Moderator, International Society for Heart and Lung Transplantation Closing Plenary Session. Convention Hall, Osaka International Convention Center, Osaka, Japan, Saturday, April 8, 2000. Invited Speaker, Nuclear Medicine Journal Club and Lecture Series, Evaluation and Management of Heart Transplant Patients. Nuclear Medicine Clinic Conference Room, CHS-AR-277, Friday, May 5, 2000. Invited Speaker, UCLA Heart Failure and Transplantation: New Concepts and Therapies, Post Transplant Management for the Primary Care Physician. The Embassy Suites at Mandalay Beach Resort, Oxnard, CA, Saturday, May 6, 2000. Invited Speaker, Educational Talk: Heart Transplant Program Update. Board of Advisors Executive Committee Meeting, Administrative Conference Room, 14-214 U, UCLA Medical Center, May 11, 2000. Co-Chair, Session: Clinical Immunosuppression. AST Chicago, Chicago Sheraton Hotel, May 15, 2000. Medicine Grand Rounds. Lecture: Reducing Cardiovascular Risk in the New Millennium: One Heart at a Time. University of California at San Diego Medical Center, San Diego, CA, May 19, 2000. Medicine Grand Rounds. Lecture: Update on Cardiac Transplantation. Harbor-UCLA Medical Center, Torrance, CA, May 23, 2000. Invited Speaker, Mini-Course, Cardiology for the Primary Care Physician: Management of Congestive Heart Failure. 27th Annual UCLA Family Practice Refresher Course. Fairmont Miramar Hotel, Santa Monica, CA, May 30-June 3, 2000. Invited Speaker, “IVUS Assessment of Cyclosporine vs. Tacrolimus. Current Perspectives in Cardiac Transplant Immunosuppression. The New York Palace Hotel, New York, NY, June 23, 2000. Invited Speaker, “Cardiac Transplantation”. Grand Rounds Educational Meeting, Kaiser Hospital Conference Rooms 2A and 2B, Fontana, CA, August 15, 2000. Invited Speaker, “Cardiovascular Disability”. Los Angeles County Bar Association’s Social Security Section, McCormick and Schmick’s Restaurant, Los Angeles, CA, September 5, 2000. Invited Speaker, Grand Rounds “Hyperlipidemia in Solid Organ Transplantation”. Medical Center, Ann Arbor, MI, September 15, 2000. University of Michigan Invited Speaker, Plenary Session: “Current Aspects on Cardiac Allograft Vasculopathy”. The Gifu Renaissance Hotel, Gifu, Japan, October 12, 2000. Invited Speaker, Japan Society for Transplantation. Heart Transplantation in the New Millennium, Main Symposium, “Transplantation: At the Start of a New Century”. The Gifu Renaissance Hotel, Gifu, Japan, October 12, 2000. Invited Speaker, Commentary on “Immunological Monitoring and Pre-term Diagnosis of Rejection Response”. The Gifu Renaissance Hotel, Gifu, Japan, October 13, 2000. 16 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, “Statins as Immunosuppressive Agents”. University of Minnesota CME Symposium: Late Complications after Solid Organ Transplantation. Royal Palms Hotel & Casitas, Phoenix, AZ, November 1-3, 2000. Medicine Grand Rounds. Advances in Heart Transplantation. UCLA Medical Center, 43-105 CHS, Los Angeles, CA November 22, 2000. Doctoring Lecture- Second year UCLA Medical Students, UCLA Medical Center, 73-105 CHS, Los Angeles, CA. January 12, 2001. Invited Speaker, “Cardiovascular Risks.” Fraternity of Friends. UCLA Covel Commons, January 23, 2001. Invited Speaker, “Heart Transplantation.” Pfizer Symposium, UCLA Medical Center, February 12, 2001. Invited Speaker, “Treatment of a Highly Sensitized Patient Prior to Heart Transplant.” Texas Heart Institute, Houston, TX, February 16, 2001. Invited Speaker, National Institute of Health Grand Rounds: “Statins as immunosuppression agents in organ transplantation.” March 14, 2001. Invited Speaker, “Hyperlipidemia Management Update: Diabetes, Low HDL, and More.” 1 st Annual UCLA Department of Medicine Clinical Faculty Association CME Symposium: Cardiovascular Medicine: 2001. The Century Plaza Hotel, Century City, CA Saturday, March 31, 2001. Moderator, “Immunosuppressive Protocols and Drug Monitoring: Defend or Deny.” International Society for Heart and Lung Transplantation Scientific Sessions, Vancouver, BC Canada. April 26, 2001. Moderator, “Immunosuppression 1: Clinical Outcome Measurements and Side Effects.” International Society for Heart and Lung Transplantation Scientific Sessions, Vancouver, BC Canada. April 26, 2001. Moderator, Luncheon Session. “Selected Posters on Heart and Lung.” American Society of Transplantation, Sheraton Hotel, Chicago, IL. May 14, 2001. Invited Speaker, Mini-Course, Cardiology for the Primary Care Physician: Approach to the Patient with Syncope. 28th Annual UCLA Family Practice Refresher Course. Fairmont Miramar Hotel, Santa Monica, CA, May 29-June 2, 2001. Invited Speaker, Cardiopulmonary Exercise Testing: A Case Study Approach Presentation 4: “Post-Transplant Assessment and Follow-Up.” AHA Scientific Sessions 2001, Anaheim Convention Center, Room 303 C-D. November 12, 2001. Moderator, Heart & Lung, “Meet the Experts” The 2 nd International Congress on Immunosuppression. San Diego, CA. December 7, 2001. Invited Speaker, Doctoring Course, Second-Year UCLA Medical Students. "Heart Transplantation". UCLA Medical Center, Los Angeles, CA. January 7, 2002. Invited Speaker, Cardiology Fellows Grand Rounds: “Transplant Coronary Artery Disease.” Presbyterian Hospital/Columbia University, New York, NY January 8-9, 2002 Invited Speaker, Cardiology Grand Rounds: “High Risk Program at UCLA.” Hospital/Columbia University, New York, NY January 8-9, 2002 17 New York New York Presbyterian CURRICULUM VITAE JON KOB ASHIGAWA, MD Moderator and Invited Speaker, Fujisawa Roundtable: Managing Cardiovascular and Immunologic Risk Factors Post-Heart Transplant: “Role of Statins.” Key West, FL February 7-8, 2002 Moderator and Participant, Group Discussion Regarding Retrospective Analysis Project: “Project Objectives” and “Publication Plans.” Key West, FL February 7-8, 2002 Invited Speaker, Transplant Coronary Artery Disease Evening Session. “Impact of Lipid Lowering”. American College of Cardiology Conference 2002. Atlanta, GA. March 17-20, 2002. Invited Speaker and Moderator, Mid-Day Workshop 4: “Cardiovascular Risk Factors Post Heart Transplant: Do They Matter and Can They be Treated?” International Society for Heart and Lung Transplantation, 22 nd Annual Meeting and Scientific Sessions. Washington D.C. April 10-13, 2002. Invited Speaker, Novartis Satellite Symposium: The Immunosuppressive Regimen: Redefining the Path to Improved Patient Outcomes. “Promising Approaches to Chronic Rejection” American Transplant Conference 2002. Washington, D.C. April 27, 2002. Invited Speaker, Mini-Course, Cardiology for the Primary Care Physician: Modern Management of Congestive Heart Failure. 29th Annual UCLA Family Practice Refresher Course. Fairmont Miramar Hotel, Santa Monica, CA, May 28-June 1, 2002. Invited Speaker, Cardiology Grand Rounds. 2002: The New Heart Transplant Odyssey – Advances in the Field. UCLA Medical Center, Los Angeles, CA, June 14, 2002. Invited Speaker, “Advances in Heart Transplantation.” Grand Rounds, Harbor-UCLA Medical Center, Los Angeles, CA. August 27, 2002. Invited Speaker, UCLA Noon Conference. “Cardiac Transplant Basics”. UCLA Medical Center, Los Angeles, CA. August 29, 2002. Invited Speaker, “Advances in Transplantation” Conference. “Cardiac Biopsies: Today’s Uses and Tomorrow’s Methods of Non-Invasive Techniques to Detect Rejection”. La Jolla, CA. October 27-30, 2002. Invited Speaker, “Advances in Transplantation” Conference. Transplant Population”. La Jolla, CA. October 27-30, 2002. “Chronic Disease Management in the Post Moderator, “Management Issues In Cardiac Transplantation”. November 17-19, 2002. AHA Scientific Session 2002. Chicago, IL. Invited Speaker, Immunosuppression in Heart Transplant: State of the Art. “The Effect of Everolimus/Sirolimus on the Development of Allograft Vasculopathy:” AHA Scientific Session 2002. Chicago, IL. November 17-19, 2002. Guest Lecturer, Doctoring II Cardiac Module, “Cardiac Transplantation.” UCLA Medical Center, Los Angeles, CA January 6, 2003. Invited Speaker, Postoperative Management: “Clinical Approach to the Treatment of Coronary Graft Vasculopathy.” 4th Vail Conference: Cardiothoracic Transplantation 2003. Vail, Colorado. February 22-26, 2003. Invited Speaker, Postoperative Management: “Rapamycin in Heart Transplantation.” Cardiothoracic Transplantation 2003. Vail, Colorado. February 22-26, 2003. 18 4 th Vail Conference CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Postoperative Management: “Cardiac Biopsies: Current Uses and Noninvasive Techniques for Rejection Monitoring.” 4th Vail Conference Cardiothoracic Transplantation 2003. Vail, Colorado. February 2226, 2003. Program Chair, Roundtable: “Heart Transplantation and Recent Advances in mTOR Inhibitors.” Boca Raton, Florida. March 17-18, 2003. Moderator, Heart Failure Press Conference. American College of Cardiology, 52 nd Annual Scientific Sessions, Hyatt Regency McCormick Place, Chicago, IL March 30-April 1, 2003 Invited Speaker, Cardiac Transplantation: “Allograft Vasculopathy.” American College of Cardiology, 52 nd Annual Scientific Sessions, Hyatt Regency McCormick Place, Chicago, IL March 30-April 1, 2003 Chair, Novartis Lunch Symposium: “TCAD: IVUS, Surrogate Markers & Treatments.” International Society for Heart and Lung Transplantation, 23rd Annual Meeting and Scientific Sessions, Vienna, Austria April 7-13, 2003 Invited Speaker, “Results of Multi-Center Study of Metabolic and Renal Factors Influencing Survival in Heart Transplantation.” International Society for Heart and Lung Transplantation, 23 rd Annual Meeting and Scientific Sessions, Vienna, Austria April 7-13, 2003 Co-Moderator, Closing Plenary Session. International Society for Heart and Lung Transplantation, 23rd Annual Meeting and Scientific Sessions, Vienna, Austria April 7-13, 2003 Co-Chair, Work Group Sessions: Diagnosis of Humoral Rejection. A Conference to Analyze Humoral Rejection in Solid Organ Transplantation, Bethesda, MD, April 23-24, 2003. Co-Chair, Plenary Session: Work Group 2: Presentation of Consensus Recommendations. A Conference to Analyze Humoral Rejection in Solid Organ Transplantation, Bethesda, MD, April 23-24, 2003. Program Co-Chair, UCLA Symposium: Cutting Edge Therapy in Heart Failure Treatment: New Concepts and Therapies. Lectures given: Advances in Heart Transplantation. Four Seasons Resort Santa Barbara, CA. May 3, 2003. Invited Speaker, “Cardiovascular Risk Factors in Transplant Recipients.” Cardiology Grand Rounds, New York Presbyterian Hospital/Columbia University, New York, NY, May 5-7, 2003. Invited Speaker, “The Immunosuppressive Effects of Statins.” General Transplant Grand Rounds, New York Presbyterian Hospital/Columbia University. May 5-7, 2003. Invited Speaker, “UCLA Heart Transplant Program.” Dinner Meeting with Heart Transplant Medical Staff. New York Presbyterian Hospital/Columbia University. May 5-7, 2003. Invited Speaker, Mini-Course: Cardiology for the Primary Care Physician: “Approach to the Patient with Syncope.” 30th Annual UCLA Family Practice Refresher Course. The Beverly Hilton, CA, May 27-May 31, 2003. Invited Speaker, Clinical Science Symposium: “Who Should Not be Transplanted/Retransplanted.” American Transplant Congress 2003, Washington D.C. May 30-June 4, 2003. Invited Speaker, Thoracic Mini-Oral Session: “Improved Survival of Heart Transplant Patients with Severe TCAD in Era of Percutaneous Coronary Intervention and Statin Therapy.” American Transplant Congress 2003, Washington D.C. May 30-June 4, 2003. Co-Chair, Heart Transplantation: Immunosuppression Protocols. Washington D.C. May 30-June 4, 2003. American Transplant Congress 2003, Invited Speaker, Thoracic: Recipient and Donor Outcomes: “Impact of On-Going Post Cardiac Transplant Risk Factors on Outcomes: A Multi-Center Study.” American Transplant Congress 2003, Washington D.C. May 30June 4, 2003. Co-Moderator, Congestive Heart Failure. American Heart Association 2 nd Asia-Pacific Scientific Forum, June 810, 2003. 19 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, “Heart Failure as it Affects Persons of Asian Descent in North America.” American Heart Association 2nd Asia-Pacific Scientific Forum, June 8-10, 2003. Invited Speaker, “Hyperlipidemia in Solid Organ Transplantation.” Kidney Transplant Grand Rounds, University of Southern California. July 14, 2003. Invited Speaker, “Adult Heart Transplant Rejection and Immunosuppression Therapy.” 4 East ICU Nursing Symposium, UCLA. September, 18, 2003. Invited Speaker, “Post-Transplant Patient Care: New Challenges.” Symposium XV: Surgery and Device Therapy in Heart Failure, 7th Annual Scientific Meeting 2003 Heart Failure Society of America, Las Vegas, NV. September 23, 2003. Invited Speaker, “Current Immunosuppression at UCLA.” Fujisawa Preceptorship, UCLA. October 15, 2003. Invited Speaker, “New Immunosuppression Therapy.” Fujisawa Preceptorship, UCLA. October 16, 2003. Invited Speaker, “Present Status and Future Trends of Immunosuppression in Heart Transplantation.” 39 th Annual Meeting of Japan Society for Transplantation, Osaka, Japan. October 27, 2003. Invited Speaker, “Current Immunosuppression Strategies in Heart Transplantation.” American Heart Association Scientific Sessions 2003, Orlando, FL. November 10, 2003. Invited Speaker, “Advanced Heart Failure, Transplantation and Devices and Heart Immunosuppression.” Cardiothoracic Grand Rounds, University of Arizona. December 4, 2003. Transplant Invited Speaker, “Current Immunosuppression at UCLA’s Heart Transplant Program.” Cardiac Transplant Grand Rounds, University of Arizona. December 5, 2003. Invited Speaker, “Advances in Heart Transplantation.” UCLA Medical School lecture Series to Second Year Medical Students, UCLA. January 20, 2004. Invited Speaker, “Exercise Capacity in Heart Transplant Patients.” Inservice, UCLA. February 18, 2004. UCLA Physical Therapy Department Program Co-Chair, UCLA Symposium: Cutting Edge Therapy in Heart Failure Treatment: New Concepts and Therapies. Lectures given: Advances in Heart Transplantation. Four Seasons Resort, Las Vegas, NV. February 21, 2004. Invited Speaker, “Advances in Heart Transplantation.” Multidisciplinary Cardiovascular Conference, Hoag Hospital Heart and Vascular Institute. Newport Beach, CA. February 25, 2004. Invited Speaker, “Transplantation 2004.” Management of End-Stage Heart Failure Symposium, American College of Cardiology 52nd Annual Scientific Sessions, New Orleans, LA. March 8, 2004. Invited Speaker, “Heart Transplantation; A Life Sustaining Organ Transplant.” Pathology 240, UCLA. April 27, 2004. Invited Speaker, “Diagnostic Approach to the Patient with Syncope.” Harvard/UCLA Pri-Med Conference. Current Clinical Issues in Primary Care. Anaheim Convention Center, Anaheim, CA. May 14, 2004. Co-Chair: Clinical Science Symposium: Pre-Transplant Risk Factors and Effect on Post-Transplantation Outcomes. American Transplant Congress 2004 Meeting. John B. Haynes Convention Center, Boston, MA. May 17, 2004. Co-Chair: Pediatric Cardiac Transplant and Post-Transplant Complications. American Transplant Congress 2004 Meeting. John B. Haynes Convention Center, Boston, MA. May 17, 2004. Invited Speaker, “Modern Management of Congestive Heart Failure.” 31 st Annual UCLA Family Practice Refresher Course. Minicourse: Cardiology for the Primary Care Physician. The Beverly Hilton Hotel. June 3, 2004. 20 CURRICULUM VITAE JON KOB ASHIGAWA, MD Program Co-Chair, UCLA Symposium: Cutting Edge Therapy in Heart Failure Treatment: Newest Concepts and Treatments. Presentations: Welcome and Introductory Remarks and Update on Heart Transplantation Management. Marriott Hotel, Newport Beach, CA. October 9, 2004. Invited Speaker, Heart Failure University: Transplant Evaluation and Post-Transplant Treatment. Los Angeles Airport Marriot, Los Angeles, CA. November 12-14, 2004. Invited Speaker, Individualization of Immunosuppression, Heart and Lung: Short-Term. Manchester Grand Hyatt San Diego, San Diego, CA. December 8-11, 2004. Invited Speaker, Roche National Cardiac Transplant Advisory Board. Presentation: The Cellcept Cardiac Registration Trial and Data Reanalysis. Chicago, IL. December 16-17, 2004. Invited Speaker, Brigham and Women’s Hospital, Transplant Grand Rounds. Presentation: Immunosuppression in Heart Transplantation. Brigham and Women’s Hospital, Boston, MA. January 11, 2005. Invited Speaker, Massachusetts General Hospital, Cardiology Grand Rounds. Presentation: Immunosuppression in Heart Transplantation. Massachusetts General Hospital, Boston, MA. January 12, 2005. Invited Speaker, Tufts-New England Medical Center, Cardiology Grand Rounds. Presentation: Immunosuppression in Heart Transplantation. Tufts-New England Medical Center, Boston, MA. January 13, 2005. Invited Keynote Speaker, The 6th Biennial Psychiatric, Psychosocial and Ethical Issues in Organ Transplantation Conference. Keynote Address: Cardiac Transplantation: Advances and Ethical Dilemmas. Doubletree Hotel, Santa Monica, CA. February 4-6, 2005. Invited Speaker, American College of Cardiology. Meet the Experts Session: Heart Transplant 2005. Orange County Convention Center, Orlando, FL. March 8, 2005. Invited Speaker, Johns Hopkins Comprehensive Transplant Center, Research Lectures: Tough Cases for the Expert. Johns Hopkins - Cardiology Library, Baltimore, MD. March 25, 2005. Invited Speaker, Johns Hopkins Comprehensive Transplant Center, Research Lecture. Transplant Lecture: Advances in Immunosuppression & Cardiac Allograft Vasculopathy After Heart Transplantation. Johns Hopkins - Cader Room, Baltimore, MD. March 25, 2005. Co-Moderator, International Society for Heart and Lung Transplantation Plenary Session. Philadelphia Marriot, Philadelphia, PA. April 9, 2005. Co-Chair: Welcome and Introductory Remarks. New Advances in Heart Failure Treatment: Newest Concepts and Therapies. Hilton Los Angeles North/Glendate & Executive Meeting Center, CA. April 16, 2005. Lecturer, The David Geffen School of Medicine at UCLA - Pathology 240 Course Spring 2005 Immunobiology of Transplantation: From Bench to Bedside, “Heart Transplantation; A Life Sustaining Organ Transplant” UCLA Center for Health Sciences, Los Angeles, CA April 26, 2005. Moderator, American Transplant Congress, Contemporary Outcomes in Immunosuppression Session. Washington State Convention and Trade Center, Seattle, WA, May 20-25, 2005. Invited Speaker, VA Greater Los Angeles Health Care System, Cardiology Grand Rounds Medical Educational Conference – Cardiology Division, James Wadsworth Building, Los Angeles, CA. June 15, 2005. Presenter, Australian Transplant Symposium. Lectures: Coronary Artery Vasculopathy and Humoral Rejection—A Historical Review. Park Hyatt Melbourne, Melbourne, Australia, July 22-23, 2005. Invited Speaker, Department of Medicine Noon Conference. Lecture: Basics in Cardiac Transplantation. UCLA, Los Angeles, CA. July 29, 2005. Invited Speaker, Cellcept Heart STN Investigators Meeting, Hyatt Regency Chicago, Chicago, IL. August 10-12, 2005. 21 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Certican Mock “B” Meeting, Westminster Hotel. Livingston, NJ. September 26-27, 2005. Invited Speaker, Advances in Transplantation--Contemporary Forums Symposium. Lectures: “Revisiting Criteria for Heart Transplantation” and “Advanced Case Studies in Thoracic Transplantation.” Las Vegas Hilton, Las Vegas, NV. September 29-30, 2005. Invited Speaker, Montreal Heart Institute. Lecture: “Advances in Immunosuppression After Heart Transplantation.” Montreal Heart Institute and Hospital Laval, Quebec City, Canada. October 4-7, 2005. Faculty Moderator, Clinical Challenges in Heart Transplantation. Four Seasons Hotel, Los Angeles, CA. October 20, 2005. Invited Speaker, Transplant Summit 2005. Lecture: “Update on the Classification of Heart Transplant Rejection." Roundtable Leader: “Transplant Cardiology and Heart Failure Roundtable.” The Westin St. Francis Hotel, San Francisco, CA October 26-28, 2005. Invited Speaker, Heart Failure University. Lecture: “Heart Transplant Evaluation and Post-Transplant Treatment.” Los Angeles Airport Marriott, Los Angeles, CA December 3-4, 2005. Facilitator, Clinical Challenges in Heart Transplantation. Seattle, WA, March 6, 2006. Invited Speaker, Roche Satellite Symposium: “Looking Beyond Cellular Rejection in Cardiac Transplantation.” International Society for Heart and Lung Transplantation, 26th Annual Meeting and Scientific Sessions, Auditorium Hotel, Madrid, Spain. April 5-8, 2006. Presenter, XDx CARGO Steering Committee breakfast meeting: “Mild Rejection/Steroid Weaning.” International Society for Heart and Lung Transplantation, 26th Annual Meeting and Scientific Sessions, Auditorium Hotel, Madrid, Spain. April 5-8, 2006. Moderator, Concurrent Session 13: CAV: A Never-ending Story. International Society for Heart and Lung Transplantation, 26th Annual Meeting and Scientific Sessions, Auditorium Hotel, Madrid, Spain. April 5-8, 2006. Presenter, Concurrent Session 17: The Cells Versus the Humors: “Flow-cytometry positive, cytotoxicity-negative donor-specific crossmatch: To transplant or not to transplant, that is the question” and “Adequate cyclosporine (CsA) microemulsion (Neoral®) C2-levels critical within the first 30 days to prevent rejection after cardiac transplant.” International Society for Heart and Lung Transplantation, 26th Annual Meeting and Scientific Sessions, Auditorium Hotel, Madrid, Spain. April 5-8, 2006. Invited Speaker, Astellas Heart Transplant Panel. Grand Hyatt Seattle, Seattle, WA. May 18, 2006. UCLA Medicine Grand Rounds: “Advances in Heart Transplantation: Where Will We Be Tomorrow?” UCLA Medical Center and School of Medicine, Los Angeles, CA, May 24, 2006. Invited Speaker, Immunosuppression Minimization in Cardiac Transplantation: “Update on Clinical Trials in Cardiac Transplantation”. World Transplant Congress Meeting 2006, Hynes Convention Center, Boston, MA, July 25, 2006. Chairman, Heart Transplant Roundtable: “Process of Care.” Hilton O’ Hare, Chicago, IL, July 14, 2006. Pfizer Visiting Professorship, Northwestern University Cardiology Grand Rounds: “Advances in Immunosuppression in Heart Transplantation.” Northwestern University Feinberg School of Medicine, Chicago, IL, September 14-15, 2006. Invited Speaker, Cleveland Clinic Grand Rounds: “Advances in Immunosuppression in Heart Transplantation.” The Cleveland Clinic Lerner Research Building, Cleveland, OH, September 24-25, 2006. Co-Chairman, New Advances in Heart Failure Treatment: Newest Concepts and Therapies: “Update on Heart Transplantation Management.” California Heart Center Continuing Medical Education Symposium, Marriott Oxnard, Ventura, CA, October 7, 2006. 22 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Pennsylvania State University Cardiology Grand Rounds: “Advances in Immunosuppression in Heart Transplantation.” Pennsylvania State University Medical Center, Hershey, PA, October 15, 2006. Invited Speaker, Drexel University Cardiology Grand Rounds: “Advances in Immunosuppression in Heart Transplantation.” Drexel University Medical Center, Philadelphia, PA, October 16, 2006. Clinical Advisor for XDx, MediCal Board of California. The Hyatt Sacramento, Sacramento CA, November 16, 2006. Invited Speaker, The Second International Conference on Heart Failure in Children and Young Adults--New Strategies for Diagnosis and Treatment of Heart Failure: “Lessons Learned from Adult Randomized Controlled Trials,” “Challenging Case Session (My Worst Nightmare),” “Roundtable: Is There a Role for Primary Transplantation for Hypopolastic Left Heart Syndrome?” The Ritz-Carlton, Laguna Niguel, CA, November 28December 2, 2006. Invited Speaker, Heart Failure University 2006: “Heart Transplant Evaluation and Post-Transplant Treatment.” Sheraton Gateway Hotel, Los Angeles, CA, December 1-3, 2006. Invited Speaker, XDx AlloMap Clinical Advisory Board Meeting: “Allograft Dysfunction and Survival.” The Oval Room Restaurant, Washington, DC, December 4-5, 2006. Moderator and Invited Speaker, NewEra Cardiac Care 2007 Meeting: “Heart Failure and Biventricular Pacing,” Heart Failure Session. The Hyatt Regency Resort & Spa, Huntington Beach, CA, January 4-7, 2007. Lecturer, The David Geffen School of Medicine at UCLA - Pathology 240 Course Spring 2006 Immunobiology of Transplantation: From Bench to Bedside, “Heart Transplantation; A Life Sustaining Organ Transplant.” UCLA Center for Health Sciences 43-130, Los Angeles, CA, April 23, 2007. Invited Speaker, Satellite Symposium 5—The Evolving Problem of Antibodies in Thoracic Transplantation: “Clinical Therapies Currently in Use: Do Any of Them Work?” International Society for Heart and Lung Transplantation, 27th Annual Meeting and Scientific Sessions, San Francisco, CA, April 24-27, 2007. Invited Speaker, Cylex Symposium: “Immune Monitoring in Heart & Lung Transplant Patients.” International Society for Heart and Lung Transplantation, 27th Annual Meeting and Scientific Sessions, San Francisco, CA, April 24-27, 2007. Invited Speaker, Immunosuppressive strategies for Transplantation in the Next Decade Advisory Board Meeting. San Francisco Marriot, San Francisco, CA, May 4, 2007. Invited Speaker, Pri-Med Conference: “Approach to the Patient with Chest Pain.” Anaheim Convention Center, Anaheim, CA, May 10, 2007. Invited Speaker, 34th Annual UCLA Family Practice Refresher Course: “Current Concepts in Atrial Fibrillation.” Hyatt Regency Centery Plaza, Los Angeles, CA, May 30, 2007. Invited Speaker, Contemporary Forums Advances in Transplantation: “Right Sided Heart Failure” and “Immune Monitoring.” La Jolla, CA, September 9-12, 2007. Invited Speaker, UCLA Heart Failure and Transplantation: New Advances in Heart Failure Treatment. The Doubletree Hotel, Santa Monica, CA, Saturday, October 12, 2007. Invited Speaker/Participant, XDx Clinical Advisory Board Meeting: “Optimizing Clinical Outcomes Study Design.” Sonoma, CA, October 10-11, 2007. Speaker/Participant, United Resource Network Site Visit with UCLA Transplant Services Programs: “Heart Transplant.” UCLA NPI Building, Los Angeles, CA, November 1, 2007. Moderator, Advances in Immunosuppression after Cardiac Transplantation. American Heart Association Scientific Sessions 2007, Orlando, FL, November 4, 2007. Discussant, Late-Breaking Clinical Trials II: CORONA trial. American Heart Association Scientific Sessions 2007, Orlando, FL, November 5, 2007. 23 CURRICULUM VITAE JON KOB ASHIGAWA, MD Quoted source, CORONA: Rosuvastatin can reduce hospitalization, some adverse events. Eric Raible, Cardiology Today, December 2007. Invited Speaker, The David Geffen School of Medicine at UCLA Cardiology Rounds: “Treatment of the sensitized patient before and after heart transplantation.” The David Geffen School of Medicine, CHS, Los Angeles, CA, November 16, 2007. Participant, Novartis EveroCAV Protocol Design Meeting. The Westin New York at Times Square, Nederlander Room, New York, NY, December 5, 2007. Invited Speaker, Heart Transplant Clinical and Scientific Updates: Improving Long Term Outcomes: “Improving Long-Term Graft Survival: Cardiac Allograft Vasculopathy.” John Hopkins University, Baltimore, MD, February 8, 2008. Webcast: http://www.jhasim.com/heart/web/site/index.cfm. Invited Speaker, Cleveland Clinic Transplantation Grand Rounds: “Management of the Highly Sensitized PreTransplant Patient.” Cleveland Clinic, Cleveland, OH, February 11, 2008. Invited Speaker, Comprehensive Transplant Center Presentation: “What all cardiologists should know about heart transplantation now and in the near future.” Ohio State University, Ross Auditorium, Columbus, OH, February 13, 2008. Invited Speaker, Comprehensive Transplant Center Presentation: “Cardiac Transplantation at the leading edge and future.” Ohio State University, Ross Auditorium, Columbus, OH, February 13, 2008. Invited Speaker, Grand Rounds: “Immune Monitoring in Heart Transplantation.” St. Luke’s Mid America Heart Institute, Crockett Center, Kansas City, MO, February 14, 2008. Medscape CME Activity Author: “Immunosuppressive Strategies for Long-term Success in Heart Transplantation.” Medscape, http://cme.medscape.com/viewprogram/8819, February 28, 2008. Invited Guest Participant, Transplant Histocompatibility Conference. Hyatt Regency O’Hare, Chicago, IL, March 2-4, 2008. Co-chairman, 72nd Annual Scientific Meeting of the Japanese Circulation Society. Lecture given: “Current Status in Cardiac Transplantation in the United States.” Fukuoka, Japan, March 28, 2008. Invited Speaker, Pathology 240 Course: “Immunobiology of Transplantation.” David Geffen School of Medicine at UCLA, 16-154 CHS, Los Angeles, CA, April 16, 2008. Invited Speaker, Harvard/UCLA Pri-Med Conference: Current Clinical Issues in Primary Care. “Management of Congestive Heart Failure.” Anaheim Convention Center, Anaheim, CA, May 15, 2008. Invited Speaker, American Transplant Congress Satellite Symposium: Extending Patient and Graft Survival, Current Barriers and Future Solutions. “Insights form Heart Transplantation.” Royal York Fairmont, Toronto, Ontario, Canada, June 2, 2008. Invited Speaker, American Transplant Congress Sunrise Symposium: Randomized Clinical Trials in Heart Transplantation. “What have Randomized Clinical Trials Taught Us So Far?” Metropolitan Toronto Convention Center, Toronto, Ontario, Canada, June 4, 2008. Invited Speaker, 35th Annual UCLA Family Practice Refresher Course: “Current Concepts in Atrial Fibrillation.” David Geffen School of Medicine at UCLA, Los Angeles, CA, May 21, 2008. Invited Speaker, CBS Television Show “The Doctors.” Los Angeles, CA, September 12, 2008. Invited Speaker, Lecture at National Cheng-Kung University Hospital: “What Have RCT’s Taught Us So Far.” Tainan, Taiwan, September 26, 2008. Invited Speaker, Lecture at National Taiwan University Hospital: “Should the Patients with Right Ventricular Failure Undergo Heart Transplantation?- Review of the Indication for Heart Transplantation.” Taipei, Taiwan, September 27, 2008. 24 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Prograf Launching 10th Anniversary Symposium: Sharing organ Transplantation, Lighting New Life. “Current Immunosuppressive Strategies in Heart Transplantation and Future Trend.” The Westin Taipei, Taipei, Taiwan, September 27, 2008. Invited Speaker, Joint Transplant Histocompatibility Conference: A Progress Report. “Report from a Consensus Conference on the Sensitized Patient Awaiting Heart Transplantation.” December 9, 2008. Invited Speaker, Cardiology Interest Group, Second Year UCLA Medical Students: “Heart Transplantation.” David Geffen School of Medicine at UCLA. April 6, 2009. Invited Speaker, Harbor-UCLA Cardiology Grand Rounds: “Advances in Heart Transplantation.” Saint John’s Cardiovascular Research Center, Torrance, CA, May 4, 2009. Invited Speaker, PRI-Med West: Current Clinical Issues in Primary Care, “Management of Atrial Fibrillation.” Anaheim Convention Center, Anaheim, CA, May 7, 2009. Featured Speaker, UCLA Department of Medicine Clinical Faculty Annual General Dinner Meeting: “Advances in Heart Transplantation.” UCLA Faculty Center, Los Angeles, CA, May 27, 2009. Invited Speaker, 36th Annual UCLA Family Practice Refresher Course: Cardiology: “Approach to the Patient with Atrial Fibrillation.” Hyatt Regency Century Plaza, Los Angeles, CA, May 29, 2009. Invited Lecturer, Internal Medicine Resident Lecture: “Basics in Heart Transplantation.” UCLA Medical Center, July 27, 2009. Invited Speaker, UCLA Cardiology Grand Rounds: “Advances in Heart Transplantation/Antibody Mediated Rejection.” UCLA Medical Center, September 4, 2009. Invited Speaker, Surgical Core Curriculum Conference: “Arrhythmia Management for Surgeons.” UCLA Medical Center, September 30, 2009. Invited Speaker, Heart Failure and Transplant Symposium: “Advances in Heart Transplantation.” Pelican Hill Resort, Newport Beach, CA, October 3, 2009. Invited Speaker, Venice Family Clinic: “Cardiac Arrhythmias.” Venice, CA, October 20, 2009. Invited Speaker, American Society of Transplantation Audioconference Series: “Cardiothoracic Transplantation: Diagnosis and Treatment of Antibody Mediated Rejection.” December 9, 2009; January 19, 2010. Invited Speaker, American College of Cardiology Symposium: “Venous Thromboembolism in Patients with Heart Failure – Assessing Risk and Optimizing Prophylaxis of VTE in HF Patients in the Hospital and Out.” Atlanta, GA, March 13, 2010. Invited Speaker, Berdie Justice Memorial Lectureship: “Advances in Heart Failure and Heart Transplantation.” Cedars-Sinai Medical Center, Los Angeles, CA, May 4, 2010. Invited Speaker, Pri-Med West: “Approach to the Patient with Syncope.” Anaheim, CA, May 6, 2010. Invited Speaker, 34th Annual Blood Donor Recognition: “Why One Blood Donation Goes A Long Way.” Cedars-Sinai Medical Center, Los Angeles, CA, June 24, 2010. Lecturer, Cedars-Sinai Department of Anesthesiology Grand Rounds: “Sensitization.” Cedars-Sinai Medical Center, Los Angeles, CA, July 28, 2010. Invited Speaker, American Society for Histocompatibility and Immunogenetics: “ASHI-Antibody Mediated Rejection in Heart Transplantation.” Hollywood, Florida, September 29, 2010. Invited Speaker, Brano Heart Failure Forum: “The future of heart transplantation.” Portoroz, Slovenia, October 2, 2010. Program Chair, Board Review Course: “Management of the Sensitized Patient Awaiting Heart Transplantation.” Los Angeles, CA, October 15, 2010. 25 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Heart Institute Cardiology Grand Rounds Presentation at Cedars-Sinai Medical Center. “State of the Art – Antibody Mediated Rejection in Heart Transplantation.” Los Angeles, CA, Jan 4, 2011. Invited Speaker, Donor/Recipient Issues: “Management of the Donor Specific HLA and non-HLA Antibodies Pre- and Post-Heart Transplantation.” Division of Cardiothoracic Surgery, University of Colorado School of Medicine. 8th Vail Cardiothoracic Transplantation: An International Update. Vail, CO, Jan 22-26, 2011. Invited Speaker, Post Transplant Issues: “Immune Monitoring Post-Heart Transplantation.” Division of Cardiothoracic Surgery, University of Colorado School of Medicine. 8th Vail Cardiothoracic Transplantation: An International Update. Vail, CO, Jan 22-26, 2011. Invited Speaker, Post Transplant Issues: “Prevention and Management of Coronary Graft Vasculopathy.” Division of Cardiothoracic Surgery, University of Colorado School of Medicine. 8th Vail Cardiothoracic Transplantation: An International Update. Vail, CO, Jan 22-26, 2011. Invited Speaker, 2011 Western Regional Meeting of the American Federation for Medical Research. “Mentor Talk: Experiences in Heart Transplant Research.” Carmel, CA, January 28, 2011. Invited Speaker, Methodist Transplant Center Grand Rounds, Methodist Hospital. “State of the Art – Antibody Mediated Rejection in Heart Transplantation.” Houston, TX, Feb 9, 2011. Invited Speaker, Legacy Society Palm Springs hosted by Cedars-Sinai Medical Center. “Advancements in Heart Transplantation.” Palm Springs Air Museum Palm Springs, CA, Mar 15, 2011. Invited Speaker, Division of Cardiology Grand Rounds Presentation at Harbor-UCLA Medical Center. “State of the Art – Antibody Mediated Rejection in Heart Transplantation.” Los Angeles, CA, March 22, 2011. Invited Speaker, American College of Cardiology Symposium: “Lipid Management in the Transplant Population.” New Orleans, LA, April 4, 2011. Invited Speaker, American College of Cardiology Symposium: “Does Gender Mismatch Increase the Risk of AntibodyMediated Rejection?” New Orleans, LA, April 4, 2011. Invited Speaker, Division of Cardiology Grand Rounds Presentation at California Pacific Medical Center. “Advances in Heart Transplantation.” San Francisco, CA, April 6th, 2011. Satellite Session CoChair, International Society of Heart and Lung Transplantation 31st Scientific Annual Meeting and Scientific Sessions. Satellite symposium 07: “Coronary Artery Vasculopathy: Form Consensus to Controversy.” San Diego, CA, April 13th, 2011. Invited speaker, International Society of Heart and Lung Transplantation 31st Scientific Annual Meeting and Scientific Sessions. “Reduction of Cardiac Allograft Vasculopathy with Everolimus over Mycophenolate Mofetil: Intravascular Ultrasound Results of a Randomized Multicenter Trial.” San Diego, CA, April 14 th, 2011. Plenary Session Co Chair, International Society of Heart and Lung Transplantation 31st Scientific Annual Meeting and Scientific Sessions. San Diego, CA, April 16th, 2011. Invited Speaker, Pri-Med Symposium: Current Clinical Issues in Primary Care “Management of Heart Failure.” Anaheim, CA, April 28th, 2011. Invited Presenter, American Transplant Congress. “Male Donor to Female Recipient in Heart Transplantation Increases the Risk of Antibody-Mediated Rejection.” Philadelphia, PA, April 30th, 2011. Invited Presenter, American Transplant Congress. “Primary Graft Dysfunction and Autopsy Findings.” Philadelphia, PA, April 30th, 2011. Invited Presenter, American Transplant Congress. “Virtual Crosshatch and Desensitization Therapy Has Reduced Time to Transplant for Sensitized Patients.” Philadelphia, PA, April 30th, 2011. Invited Presenter, American Transplant Congress. “The Category of Biopsy-Negative Rejection in Heart Transplantation.” Philadelphia, PA, April 30, 2011. 26 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Presenter, American Transplant Congress. “Screening Nuclear Stress Testing as a Prognostic Maker after Heart Transplantation.” Philadelphia, PA, May 1, 2011. Invited Speaker, American Transplant Congress Symposium: Improving Long-Term Survival in Thoracic Transplantation. “How to Stop Chronic Heart and Lung Graft Injury from Antibody Medicated Rejection” Philadelphia, PA, May 2, 2011. Invited Speaker, American Transplant Congress Symposium: Out with the Old? Novel Immunosuppression in Cardiac Transplantation. “CMV Infections Are Less Frequent in De Novo Heart Transplant Recipients Receiving Immunosuppression with Everolimus Plus Reduced CsA Compared to MMF and Standard CsA.” Philadelphia, PA, May 2, 2011. Invited Speaker, 13th Annual Board of Governors Healthcare College at Cedars-Sinai Medical Center. “The Future of Cardiology: From Heart Transplantation to the Total Artificial Heart.” Los Angeles, CA, May 3, 2011. Program Director and Speaker, Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management.” California Heart Center at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Hyatt Regency, Bakersfield, CA, May 21, 2011. Invited Speaker, UCLA Family Practice Refresher Course. “Management of Atrial Fibrillation.” Hyatt Regency Century Plaza, Century City, CA, May 23, 2011. Invited Speaker, The AMIRA Fibrosis Taskforce Meeting: Fibrosis Symposium. “Roadblocks for the Research and Development of New Compounds in Fibrosis.” La Jolla, CA, July 14, 2011. Program Director and Speaker, Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management.” California Heart Center at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Hyatt Regency, Newport Beach, CA, September 17, 2011. Invited Speaker, 15th Annual Scientific Meeting 2011 Heart Failure Society of America: Continuing Medical Education Symposium. Before and After Cardiac Transplantation “Double-Organ Transplantation: Who and Why?” Hynes Convention Center, Boston, MA. September 20, 2011. Invited Panel Member, International Heart Failure Forum: Innovations and New Treatment Strategies in Heart Failure. “Acute Heart Failure Patients.” Portoroz, Slovenia. September 23, 2011. Invited Speaker, International Heart Failure Forum: Innovations and New Treatment Strategies in Heart Failure. Advanced Heart Failure Patient: “Candidate Selection for Heart Transplantation.” Portoroz, Slovenia. September 23, 2011. Invited Chair, Fourth International Branislav “Brano” Randovancevic Heart Failure Forum “End Stage Heart Failure Treatment: Historical and Future Perspective.” Belgrade, Serbia. September 29, 2011. Invited Speaker, Fourth International Branislav “Brano” Randovancevic Heart Failure Forum “Humoral Rejection in Heart Transplantation.” Belgrade, Serbia. October 1, 2011. Invited Speaker, French Heart Transplantation Congress: Coronary Graft Disease: Current Status and Perspectives. Graft Coronary Disease: Different Mechanisms and the Challenge of Early Detection “Methods of Investigation of Coronary Graft Disease” and “Local Practices of Detection in the United States.” Paris, France. October 12, 2011. Invited Speaker, French Heart Transplantation Congress: Coronary Graft Disease: Current Status and Perspectives. Management of Coronary Graft disease: “Therapeutic Approaches of Coronary Graft Disease: News and Perspectives—What Treatments, When to Intervene” and “Local Practices in the United States.” Paris, France. October 12, 2011. Invited Speaker, French Heart Transplantation Congress. Coronary Graft Disease: Current Status and Perspectives. Immunosuppression: “Results of Multicenter Study Certican vs. Cellcept in de Novo Heart Transplantation, IVUS Analysis.” Paris, France. October 13, 2011. Course Chair and Speaker, Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management.” California Heart Center at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Platinum Hotel, Las Vegas, NV, October 22, 2011. 27 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Core Curriculum Lecture for General Cardiology Fellows—Introduction to Transplant Cardiology. Cedars-Sinai Medical Center, Los Angeles, CA, November 22, 2011. Invited Speaker, Cedars-Sinai Emergency Department Symmposium “Caring for the Patient Post-Heart Transplant.” Four Seasons Hotel, Los Angeles, CA, Dec 2, 2011. Keynote Speaker, Cedars-Sinai Board of Directors Annual Meeting “The Total Artificial Heart and Other Innovations in Advanced Heart Disease.” Four Seasons Hotel, Los Angeles, CA, Dec 13, 2011. Invited Speaker, Core Curriculum Lecture for General Cardiology Fellows “Research in Progress Lecture.” Cedars-Sinai Medical Center, Los Angeles, CA, Dec 15, 2011. Invited Speaker, Personalized Medicine World Conference (PMWC) conference. “Genomics and the Detection of Heart Transplant Rejection.” Silicon Valley, CA, Jan 23, 2012. Invited Speaker, Cedars-Sinai Psychiatry Grand Rounds. “Heart Transplantation: Advances and Ethical Dilemmas.” Cedars-Sinai Medical Center, Los Angeles, CA, Feb 9, 2012. Invited Speaker, Medicine in Motion 5th Annual Speaker Series, “Innovations at Work Targeting Advanced Heart Disease.” Santa Barbara, CA, Mar 15, 2012. Session Co-Chair, American College of Cardiology 2012, “Heart Transplantation Challenges in 2012.” McCormick Place, Chicago, IL, Mar 25, 2012. Invited Speaker, Pri-Med Symposium: Current Clinical Issues in Primary Care “Approach to the Patient with Syncope.” UCLA, Anaheim, CA, April 13, 2012. Invited Co-Chair, International Society of Heart and Lung Transplantation 32st Scientific Annual Meeting and Scientific Sessions Pre-meeting Symposium 14: “The DEFs of AMR: Detecting the Antibodies, Evaluating the Biopsy, and Finally the Patient.” Prague, Czech Republic, April 18, 2012. Invited Moderator, One Lambda Symposium. Clinical Relevance of DSA in Thoracic Transplantation. “The Clinical Impact of DSA: Management of Sensitized Heart Transplant Recipient.” Prague, Czech Republic, April 18, 2012. Invited Speaker, International Society of Heart and Lung Transplantation 32st Scientific Annual Meeting and Scientific Sessions Concurrent Abstract Session 26: Heart Transplant Immunosuppression: What Can We Learn from Clinical Trials. “Multi-Center Randomized Trial of Eveorlimus vs. Mycophenolate Mofetil in Heart Transplantation: Final 24-Month Analysis of Efficacy and Safety.” Prague, Czech Republic, April 19, 2012. Invited Co-Chair, International Society of Heart and Lung Transplantation 32st Scientific Annual Meeting and Scientific Sessions Concurrent Abstract Session 42: Featured Abstracts. Prague, Czech Republic, April 20, 2012. Invited Speaker, Cedar-Sinai Medical Grand Rounds, “Advances in Heart Transplantation.” Cedars-Sinai Medical Center, Los Angeles, CA, May 4, 2012. Course Director and Speaker, Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management.” California Heart Center at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Crown Plaza Hotel, Ventura, CA, May 12, 2012. Invited Speaker, American Transplant Congress 2012. Joint Plenary Session II: Heart Transplant Immunosuppression: “Effect of Everolimus Based Immunosuppression on De Novo Heart Transplant Recipient: 24-Months Efficacy and Safety Results from A2310 Study” John B. Hynes Convention Center, Boston, MA, June 4, 2012. Invited Speaker, American Transplant Congress 2012. Luncheon Workshop: Meet the Experts: Practical Approach to Circulating Antibodies for Patients Awaiting Heart Transplantation…or Making Sense of the Sensitized Patient. John B. Hynes Convention Center, Boston, MA, June 5, 2012. Invited Speaker, American Transplant Congress 2012. Concurrent Session 44: Heart: Post-Operative Outcomes and Allosensitization. “Are Sensitized VAD Patients Similar to Sensitized Non-VAD Patients in Terms of Outcomes” John B. Hynes Convention Center, Boston, MA, June 5, 2012. 28 CURRICULUM VITAE JON KOB ASHIGAWA, MD Course Chair and Moderator, Success with Failure: The Nursing Perspective of Heart Failure, Mechanical Circulatory Support and Cardiac Transplantation. Opening Plenary Session. California Heart Center Foundation at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Universal Hilton, Los Angeles, CA, June 7, 2012. Course Chair and Speaker, Success with Failure: The Nursing Perspective of Heart Failure, Mechanical Circulatory Support and Cardiac Transplantation, “Heart Transplantation: Then and Now.” California Heart Center Foundation at the CedarsSinai Heart Institute Continuing Medical Education Symposium, Universal Hilton, Los Angeles, CA, June 7, 2012. Invited Speaker, Current Clinical Issues in Primary Care. Session 7: Common Problems in Ambulatory Care. “Approach to the Patient with Syncope.” Anaheim Convention Center, Anaheim, CA, April 13, 2012. Moderator, Immunosuppression in Heart Transplantation. 24th International Congress of the Transplantation Society. International Congress Center, Berlin, Germany, July 17, 2012. Invited Speaker, Immunotherapy after Heart and Lung Transplantation. “Sensitized Patients, Diagnosis and Therapy of Antibody-Mediated Rejection.” International Congress Center, Berlin, Germany, July 18, 2012 Invited Speaker. Clinical Fundamentals: Options for Advanced Heart Failure and Clinical Pearls. “Cardiac Transplantation: Individualizing Immune Suppression.” Heart Failure Society of America Annual Scientific Meeting, Washington State Convention Center, Seattle, WA, September 12, 2012. Course Director and Speaker. Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management.” California Heart Center at the Cedars-Sinai Heart Institute Continuing Medical Education Symposium, Riverside Marriott, Riverside, CA, September 15, 2012. Invited Speaker. 2012 Louis Eni Visiting Professorship. “Advances in Heart Transplantation: Promises of Tomorrow.” Drexel University, Philadelphia, PA, October 3, 2012. Invited Interviewee. “Selecting Options For The Patient with Advanced Heart Failure: Is Transplant Still An Option?” ACCEL Interview at the American College of Cardiology Conference, Los Angeles, CA, November 6, 2012. Invited Speaker. “Selecting Options For The Patient with Advanced Heart Failure: Is Transplant Still An Option?” American Heart Association Annual Scientific Meeting, Los Angeles Convention Center, Los Angeles, CA, November 6, 2012. Planning Committee Member. American Transplant Congress 2013 Planning Meeting. New Orleans, LA, January 16-18, 2013. Invited Speaker. American Society of Transplantation: Cutting Edge of Transplantation Meeting. Speed Roundtable Discussions and Dinner: “Best Treatments for AMR.” Phoenix, AZ, February 15, 2013. Invited Speaker. American Society of Transplantation: Cutting Edge of Transplantation Meeting. Controversies in Antibodies in Transplantation: “What Is the Importance of Antibodies and AMR in Heart Transplantation?” Phoenix, AZ, February 16, 2013. Presenter. American Society of Transplantation: Cutting Edge of Transplantation Meeting. Controversies in Antibodies in Transplantation: “ATG Induction Improves Outcome for Sensitized Patients Who Have Undergone Heart Transplantation.” Phoenix, AZ, February 16, 2013. Invited Speaker, “Don’t Forget the Science! How to Balance a Career in Investigation and Clinical Heart Failure.” American College of Cardiology 2013 Symposium: Careers in Heart Failure and Transplant, San Francisco, CA, March 9, 2013. Cardiology Grand Rounds: Advances in Heart Transplantation. UT Southwestern Medical Center, March 27, 2013. Chair. International Society for Heart and Lung Transplantation: 33rd Annual Meeting and Scientific Sessions. Primary Graft Dysfunction Consensus Conference. Palais des Congres, Montreal, Canada, April 23, 2013. Presenter. International Society for Heart and Lung Transplantation: 33 rd Annual Meeting and Scientific Sessions. Concurrent Session 8: Heart 3: Coronary Artery Vasculopathy in 2013- Diagnosis, Prognosis and Treatment. “Change in Maximum Intimal Thickness with Everolimus-Based Immunosuppression after Heart Transplantation in Patients at Increased Risk of Cardiac Allograft Vasculopathy.” Palais des Congres, Montreal, Canada, April 25, 2013. 29 CURRICULUM VITAE JON KOB ASHIGAWA, MD Presenter. International Society for Heart and Lung Transplantation: 33 rd Annual Meeting and Scientific Sessions. Poster Session 2: Heart Diagnostics/Therapeutics. “Results of a Randomized Trial of Allomap vs. Heart Biopsy in the 1st Year after Heart Transplant: Early Invasive Monitoring Attenuation through Gene Expression Trial.” Palais des Congres, Montreal, Canada, April 25, 2013. Presenter. International Society for Heart and Lung Transplantation: 33rd Annual Meeting and Scientific Sessions. Concurrent Session 20: Heart 5: Advances in Interpretation of Cardiac Allograft Immune Activation. “Cylex Scores May Predict Risk for Infection in the First Year Following Heart Transplantation.” Palais des Congres, Montreal, Canada, April 26, 2013. Invited Speaker. International Society for Heart and Lung Transplantation: 33 rd Annual Meeting and Scientific Sessions. ISHLT and AST Joint Session II: Antibody-Mediated Rejection: State of the “Current” Art. “Treatment Strategies in AMR in Thoracic Transplantation.” Palais des Congres, Montreal, Canada, April 26, 2013. Invited Speaker. International Society for Heart and Lung Transplantation: 33 rd Annual Meeting and Scientific Sessions. Plenary Session: From Bench to Bedside. “ISHLT Consensus Conference Report: Primary Graft Failure in Heart Transplantation.” Palais des Congres, Montreal, Canada, April 27, 2013. Invited Speaker, Pri-Med West 2013. “A Clinical Approach to Heart Failure Treatments”. Anaheim, CA, May 7, 2013. Invited Speaker, Optimal Care and New Therapies for Advanced Heart Disease. “Heart Transplantation: State of the Art Management”. Hyatt Regency, Long Beach, CA, May 11, 2013 Moderator: Optimal Care and New Therapies for Advanced Heart Disease. “Morning Session”. Hyatt Regency, Long Beach, CA, May 11, 2013. Invited Speaker, 6th Greater Milwaukee Heart Failure Society Lecture Series. “Surveillance and Treatment for Rejection after Heart Transplantation”. Milwaukee, Wisconsin. Moderator. Advances in Cardiac Transplantation. American Transplant Congress. Seattle, Washington, May 19, 2013. Presenter. American Transplant Congress. Concurrent Session 19: Predicting Rejection and Outcomes: Cells and Antibodies. “Poor Outcomes in Non-Sensitized Patients Developing de Novo Circulating Antibodies after Heart Transplantation.” Washington State Convention Center, Seattle, Washington, May 19, 2013. Presenter. American Transplant Congress. Concurrent Session 28: Medications and Outcomes in Heart Transplantation. “North American Results from the Multicenter Randomized Trial of Everolimus vs. Mycopheonlate Mofetil in Heart Transplantation.” Washington State Convention Center, Seattle, Washington, May 20, 2013. Presenter. American Transplant Congress. Concurrent Poster Session D: Late Breaking. “Intravascular Ultrasound (IVUS) Results of a Randomized Trial of Allomap vs. Heart Biopsy in the First Year After Heart Transplant.” Washington State Convention Center, Seattle, Washington, May 21, 2013. Invited Speaker, 40th Annual UCLA Family Practice Refresher Course. “Atrial Fibrillation Update: 2013.” Hyatt Regency, Los Angeles, California, May 24, 2013. Invited Speaker, Medical Grand Rounds. “ Advances in Heart Transplantation”. Cedars-Sinai Medical Center. Los Angeles, CA, June 28, 2013. Invited Speaker, 6th International Symposium for Innovations and New Treatment Strategies in Heart Failure. “Improving Survival During Heart Transplantation: Diagnosis of AMR and Techniques for the Prevention of Graft Injury”. Split, Croatia, September 10 & 11, 2013. Chair, 6th International Symposium for Innovations and New Treatment Strategies in Heart Failure. “Elderly Heart Failure Population”. Krakow, Poland, September 13th, 2013. Chair, 6th International Symposium for Innovations and New Treatment Strategies in Heart Failure. “Acute Rejection”. Krakow, Poland, September 14th, 2013. 30 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, Heart Failure Society of America 17th Annual Scientific Meeting. “Desensitization Strategies for Allosensitized Patients”. Orlando, Florida, September 24, 2013. Course Director, Experts in MCS Therapy: Current State of the Art. Century City, CA, September 2, 2013. Invited Speaker, Experts in MCS Therapy: Current State of the Art. “Management of Sensitized MCS Patients Awaiting Heart Transplantation”. Century City, CA, September 2, 2013. Conference Chair, Forum on U.S. Heart Allocation Policy. Dallas, Texas, November 15, 2013. Invited Speaker, American Heart Association Scientific Sessions 2013. “Don’t Be So Sensitive: Is Desensitization Therapy Necessary”. Dallas Convention Center, Dallas, Texas, November 17, 2013. Moderator, Controversies in Heart Failure Therapy Section. 24th Annual Meeting of the California ACC: Controversies & Advances in the Treatment of Cardiovascular Disease. Beverly Hills Hotel, Beverly Hills, CA, November 21 & 22, 2013. Invited Speaker, Advances in Heart Failure Therapy: Where Are We Now? 24th Annual Meeting of the California ACC: Controversies & Advances in the Treatment of Cardiovascular Disease. Beverly Hills Hotel, Beverly Hills, CA, November 21 & 22, 2013. Speaker, “Current Update in Heart Transplant” Patient Education Series, Los Angeles, California, December 5th, 2013. Invited Speaker, Cardiology Grand Rounds. Advances in Heart Transplant. University of California – Los Angeles Harbor Medical Center, Torrance, CA, February 4, 2014. Invited Speaker, Cedars-Sinai Surgical Grand Rounds. Current State of Heart Transplant. Cedars-Sinai Medical Center, Los Angeles, CA, February 12, 2014. Invited Speaker, Primary Graft Dysfunction. AlloMap® Medical Advisory Board Meeting, Los Angeles Airport Marriot, Los Angeles, CA, February 17, 2014. Invited Speaker, Review of eIMAGE. AlloMap® Medical Advisory Board Meeting, Los Angeles Airport Marriot, Los Angeles, CA, February 17, 2014. Invited Interviewee, Heart to Heart Conversation. SLS Hotel, Beverly Hills, CA, February 25, 2014. Invited Speaker, Pri-Med Symposium: Current Clinical Issues in Primary Care “Approach to the Patient with Syncope.” UCLA, Anaheim, CA, March 28, 2014. Co-Chair, Cardiorenal Syndrome: Tip of an Iceberg? American College of Cardiology 63 rd Annual Scientific Sessions & Expo, Washington, DC, March 29-31, 2014. Participant, When to Consider other Organ Transplantations with Cardiac Transplantations? American College of Cardiology 63rd Annual Scientific Sessions & Expo, Washington, DC, March 29-31, 2014. Invited Speaker, Heart Failure and Transplant: Where will We Be in 2024? International Society of Heart and Lung Transplantation 34th annual Meeting & Scientific Sessions, San Diego, CA, April 10-13, 2014 Invited Speaker, Sensitized VAD Patients Awaiting Heart Transplantation: Are They Different? International Society of Heart and Lung Transplantation 34th annual Meeting & Scientific Sessions, San Diego, CA, April 10-13, 2014 Invited Speaker, Long-term Care of Heart Transplant Recipients. International Society of Heart and Lung Transplantation 34th annual Meeting & Scientific Sessions, San Diego, CA, April 10-13, 2014 Invited Speaker, “Management of Heart Failure”. UCLA Family Practice Refresher Course, Hyatt Hotel, Century City, May 20, 2014. Speaker, “Current Update in Heart Transplant” Patient Education Series, Los Angeles, California, May 29th, 2014. 31 CURRICULUM VITAE JON KOB ASHIGAWA, MD Speaker, Welcome and Introductory Remarks. Bakersfield Heart Hospital – Heart Failure Preceptorship, CedarsSinai Medical Center, Los Angeles, California, May 30, 2014. Course Director, Bakersfield Heart Hospital – Heart Failure Preceptorship, Cedars-Sinai Medical Center, Los Angeles, California, May 30, 2014 Invited Speaker, Advances in Heart Failure Treatment: Looking to the Future. Bakersfield Heart Hospital – Heart Failure Preceptorship, Cedars-Sinai Medical Center, Los Angeles, California, May 30, 2014. Invited Speaker, eIMAGE data; AlloMap/AMR patients. Intermountain Med Center. University of Utah/VA; Primary Children’s Hospital, Salt Lake City, Utah, June 2, 2014. Invited Speaker, “The Future of Organ Transplantation”. 3rd National Congress of Spanish Society of Transplantation, Valencia, Spain, June 8, 2014. Invited Speaker, “Statins in Organ Transplantation”. 3rd National Congress of Spanish Society of Transplantation, Valencia, Spain, June 8, 2014. Invited Speaker, “Hear Transplantation and the Cedars-Sinai Medical Center”. Trade Commissioners Networking Group. Cedars-Sinai Medical Center, Los Angeles, California, July 23, 2014. Invited Speaker, “MCS Total Artificial Support”. 10th Annual Conference of American Association of Heart Failure Nurses, Los Angeles, California, June 27, 2014. Invited Speaker, “Heart Transplantation Multidisciplinary Panel: When to Refer, Patient/Donor Selection, Immunosuppression Overview”. 10th Annual Conference of American Association of Heart Failure Nurses, Los Angeles, California, June 27, 2014. Invited Speaker, “Looking Forward, Understanding, and Limiting the Long-term Consequences of Cardiac Antibody Mediated Rejection”. World Transplant Congress, San Francisco, California, July 27, 2014. Invited Speaker, “State of the Art Symposium - Primary Graft Dysfunction: Definition and Clinical Overview”. World Transplant Congress, San Francisco, California, July 29, 2014. Invited Speaker, “Fellows Conference: Advances in Heart Transplantation”. Grand Rounds, Queens Hospital, Honolulu, Hawaii, October 10, 2014. Invited Speaker, “Advances in Heart Transplantation”. Surgical Alternatives in Advanced Heart Failure. Honolulu, HI. October 11, 2014, Honolulu, Hawaii. Course Chair, Visiting Professorship, Queens Hospital, Honolulu, Hawaii. October 10, 2014 Invited Speaker, “Management of Primary Graft Dysfunction Following Transplant”. 16th Annual Heart Failure Summit. Cleveland Clinic, Cleveland, Ohio, October 17, 2014 Invited Speaker, “Advances in Heart Transplantation”. Grand Rounds, University of Pittsburg Medical Center, Pittsburg, Pennsylvania. November 4, 2014. Moderator, Don’t Go Rejecting My Heart: Management Considerations in Heart Transplantation. American Heart Association Scientific Sessions 2014. November 18, 2014 Invited Speaker, “Immune Monitoring: Thinking Outside the Box”. American Heart Association Scientific Sessions 2014. November 18, 2014. Program Director, Controversies & Advances in the Treatment of Cardiovascular Disease. Montage Beverly Hills, Beverly Hills, California. November, 20-21, 2014. Invited Discussant, “HeartMate II vs. HeartWare: Which is Better?”. Controversies & Advances in the Treatment of Cardiovascular Disease. Montage Beverly Hills, Beverly Hills, California. November, 20, 2014. 32 CURRICULUM VITAE JON KOB ASHIGAWA, MD Invited Speaker, “Recreational Marijuana is Not a Contraindication for Heart Transplantation”. Controversies & Advances in the Treatment of Cardiovascular Disease. Montage Beverly Hills, Beverly Hills, California. November, 20, 2014. Invited Speaker, “Advances in Heart Transplantation”. Surgery Grand Rounds, Cedars-Sinai Medical Center, Los Angeles, California. November 26, 2014. Chairman, Heart Allocation Policies: The Times They Are A-Changin', International Society for Heart and Lung Transplantation. Nice, France, April 15th, 2015. Invited Speaker, “Use of AlloMap in the AMR Era: Application of EIMAGE Results and Cedars-Sinai Experience”. International Society for Heart and Lung Transplantation. Nice, France, April 16th, 2015. Invited Speaker, “Use of Cell-free DNA in the Detection of Heart Transplant Rejection (and New Findings with AlloMap)”. International Society for Heart and Lung Transplantation. Nice, France, April 16 th, 2015. Chairman, Allomap Scientific Symposium, International Society for Heart and Lung Transplantation. Nice, France, April 16th, 2015. Discussant, Heart Transplantation Poster Session, International Society for Heart and Lung Transplantation. Nice, France, April 16th, 2015. Invited Speaker, “The Timecourse Development of Anti-HLA Antibodies Following Heart Transplantation”. International Society for Heart and Lung Transplantation. Nice, France, April 17th, 2015. Chairman, Consensus Conference on Donor Heart Selection and Management, American Transplant Congress, Philadelphia, Pennsylvania, May 1st, 2015. Chairman, Discussion Forum on US Heart Allocation Policy, American Transplant Congress. Philadelphia, Pennsylvania, May 4th, 2015. Invited Speaker, “Current Immune Monitoring in Heart Transplantation: Allomap, ImmuneKnow, Others (BNP, CRP, Troponin) - Advantages and Limitation”. American Transplant Congress. Philadelphia, Pennsylvania, May 2nd, 2015. Invited Speaker, “Plasma Levels of Donor-Derived Cell-Free DNA Increase With Rejection and Often Decrease After Treatment in Organ Transplant Recipients”. American Transplant Congress, Plenary Session II. Philadelphia, Pennsylvania, May 4th, 2015. Invited Speaker, “Natural History of Anti- Human Leukocyte Antigen Antibodies After Hear Transplant”. American Transplant Congress. Philadelphia, Pennsylvania, May 4th, 2015. Moderator, When Transplanting a Heart is Not Enough - The Role of Dual Organ Transplantation American Transplant Congress. Philadelphia, Pennsylvania, May 4th, 2015. Moderator, Antibodies in Thoracic Transplantation - Shedding New Light on the Subject . Philadelphia, Pennsylvania, May 4th, 2015. Invited Speaker, “Leading edge science and technology in advanced heart disease”. 2015 Health Seminar Lecture sponsored by the Joint Chinese University Alumni Association, El Monte, CA, August 18th, 2015. P U B L I CA T I O N S : J O U R NA L S 1. Stevenson LW, Dadourian BJ, Kobashigawa J, Child JS, Clark SH, Laks H. Mitral regurgitation after cardiac transplantation. Am J Cardiol 1987;60:119-22. 33 CURRICULUM VITAE JON KOB ASHIGAWA, MD 2. Kobashigawa J, Stevenson LW, Moriguchi J, Westlake C, Wilmarth J, Kawata N, Chuck C, Lewis W, Drinkwater D, Laks H. Randomized study of high dose oral cyclosporine therapy for mild acute cardiac rejection. J Heart Lung Transplant 1989;8:53-8. 3. Walden JA, Stevenson LW, Dracup K, Wilmarth J, Kobashigawa J, Moriguchi J. Heart transplantation may not improve quality of life for patients with stable heart failure. Heart Lung 1989;18:497-506. 4. Stevenson LW, Sietsema K, Tillisch JH, Lem V, Walden J, Kobashigawa JA, Moriguchi J. Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure. Circulation 1990;81:78-85. 5. Martin SM, Laks H, Drinkwater DC, Warner-Stevenson L, Kawata N, Kobashigawa JA, Moriguchi JD, Hamilton MA. Cardiac transplantation: the UCLA experience 1984 to 1990. Clin Transpl 1990;103-14. 6. Kobashigawa JA, Murphy FL, Stevenson LW, Moriguchi JD, Kawata N, Kamjoo P, Brownfield E, Wilmarth J, Leonard L, Chuck C, Drinkwater DC, Laks H. Low-dose lovastatin safely lowers cholesterol after cardiac transplantation. Circulation 1990;82:281-3. 7. Stevenson LW, Tillisch JH, Hamilton MA, Luu M, Chelimsky-Fallick C, Moriguchi J, Kobashigawa J, Walden J. Importance of hemodynamic response to therapy in predicting survival with ejection fraction less than or equal to 20% secondary to ischemic or nonischemic dilated cardiomyopathy. Am J Cardiol 1990; 66:1348-54. 8. Stevenson LW, Hamilton MA, Tillisch JH, Moriguchi JD, Kobashigawa JA, Creaser JA, Drinkwater DC, Laks H. Decreasing survival benefit from cardiac transplantation for outpatients as the waiting list lengthens. J Am Coll Cardiol 1991;18:919-25. 9. Cates J, Chavez M, Laks H, Drinkwater D, Stevenson L, Kobashigawa J, Saunders K, Abedin M, Roslyn J. Gastrointestinal complications after cardiac transplantation: a spectrum of diseases. Am J Gastroenterol 1991;86:412-16. 10. Krivokapich J, Stevenson LW, Kobashigawa J, Huang SC, Schelbert HR. Quantification of absolute myocardial perfusion at rest and during exercise with positron emission tomography after human cardiac transplantation. J Am Coll Cardiol 1991;18:512-17. 11. Kobashigawa JA, Stevenson LW, Brownfield ED, Moriguchi JD, Kawata N, Fandrich R, Drinkwater DC, Laks H. Initial success of steroid weaning late after heart transplantation. J Heart Lung Transplant 1992;11:428-30. 12. Stevenson LW, Warner SL, Hamilton MA, Moriguchi JD, Chelimsky-Fallick C, Fonarow GC, Kobashigawa J, Drinkwater DC, Laks H. Modeling distribution of donor heart to maximize early candidate survival. Circulation 1992;86:224-30. 13. Stevenson LW, Warner SL, Kobashigawa JA, Drinkwater DC, Laks H. Modeling a solution to the waiting list crisis. J Heart Lung Transplant 1992; in press. 14. Chelimsky-Fallick C, Stevenson LW, Middlekauff HR, Stevenson WG, Kobashigawa J, Saxon LA, Moriguchi J, Brownfield ED, Hamilton MA, Drinkwater D, Laks H, et al. Amiodarone therapy does not compromise subsequent heart transplantation. J Am Coll Cardiol 1992;20:1556-61. 15. Ardehali A, Laks H, Drinkwater DC, Ziv ET, Sorensen TJ, Hamilton MA, Warner-Stevenson L, Moriguchi JD, Kobashigawa JA. Cardiac transplantation at UCLA. Clin Transp 1993:119-27. 16. Kobashigawa JA, Stevenson LW, Brownfield ED, Moriguchi JD, Kawata N, Hamilton M, Minkley R, Drinkwater D, Laks H. Does short-course induction with OKT3 improve outcome after heart transplantation? A randomized trial. J Heart Lung Transplant 1993;12:205-8. 17. Kobashigawa JA, Stevenson LW, Moriguchi JD, Kawata N, Brownfield E, Drinkwater DC, Laks H. Is intravenous glucocorticoid therapy better than an oral regimen for asymptomatic cardiac rejection? A randomized trial. J Am Coll Cardiol 1993;21:1142-4. 34 CURRICULUM VITAE JON KOB ASHIGAWA, MD 18. Kobashigawa JA, Kirklin JK, Naftel DC, Bourge RC, Ventura HO, Mohanty PK, Cintron GB, Bhat G. Pretransplantation risk factors for acute rejection after heart transplantation: a multi-institutional study. The Transplant Cardiologists Research Database Group. J Heart Lung Transplant 1993;12:355-66. 19. Kobashigawa JA, Warner-Stevenson L, Johnson BL, Moriguchi JD, Kawata N, Drinkwater DC, Laks H. Influenza vaccine does not cause rejection after cardiac transplantation. Transplant Proc 1993;25:27389. 20. Kobashigawa JA, Stevenson LW. Postoperative treatment of heart transplant recipients. (Review article). J Crit Illness 1993;8:607-15. 21. Kobashigawa JA, Stevenson LW. Managing complications in heart transplant recipients. Improve techniques and medications increase survival rates. J Crit Illness 1993;8:678-9 (review). 22. Laks H, Gates RN, Ardehali A, Capouya ER, Moriguchi JD, Kobashigawa JA, Stevenson LW. Orthotopic heart transplantation and concurrent coronary bypass. J Heart Lung Transplant 1993;12:81015. 23. Miller LW, Schlant RC, Kobashigawa J, Kubo S, Renlund DG. 24th Bethesda Conference: Cardiac Transplantation. Task Force Complications. J Am Coll Cardiol 1993;22:41-54. 24. Stevenson LW, Warner SL, Steimle AE, Fonarow GC, Hamilton MA, Moriguchi JD, Kobashigawa JA, Tillisch JH, Drinkwater DC, Laks H. The impending crisis awaiting cardiac transplantation. Modeling solution based on selection. Circulation 1994;89:450-7. 25. Chan SY, Kobashigawa J, Stevenson LW, Brownfield E, Brunken RC, Schelbert HR. Myocardial blood flow at rest and during pharmacological vasodilation in cardiac transplants during and after successful treatment of rejection. Circulation 1994;90:204-12. 26. Kobashigawa JA. Can we prevent CMV disease after heart transplantation? J Critical Illness 1994;9:907. 27. Ardehali A, Laks H, Drinkwater DC, Kobashigawa JA, Moriguchi JD, Drake TA. Vascular cell adhesion molecule-1 (VCAM-1) up-regulation precedes and predicts cellular rejection of human cardiac allografts. Am Coll Surgeons 1994;45:312-14. 28. Kobashigawa JA, Stevenson LW, Brownfield ED, Gleeson MP, Moriguchi JD, Kawata N, Minkley R, Drinkwater DC, Laks H. Corticosteroid weaning late after cardiac transplantation: relation to HLA-DR mismatching and long-term metabolic benefits. J Heart Lung Transplant 1995;14:963-7. 29. Kobashigawa JA, Katznelson S, Laks H, Johnson JA, Yeatman L, Wang XM, Chia D, Terasaki PI, Sabad A, Cogert GA, Trosian K, Hamilton MA, Moriguchi JD, Kawata N, Hage A, Drinkwater DC, Stevenson LW. Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med 1995;333:621-7. 30. Katznelson S, Kobashigawa JA. Dual roles of HMG-CoA reductase inhibitors in solid organ transplantation: lipid lowering and immunosuppression. Kidney Int Suppl 1995;52:S112-5 (review). 31. Kobashigawa JA. Invited Commentary: Optimal timing and indications for cholecystectomy in cardiac transplant patients. World J Surg 1995 Jul-Aug;19(4):661-7. 32. Johnson JA, Kobashigawa JA. Quantitative analysis of transplant coronary artery disease with use of intracoronary ultrasound. J Heart Lung Transplant 1995;14:S198-202. 33. Kobashigawa JA, Miller L, Yeung A, Hauptman P, Ventura H, Wilensky R, Valantine H, Weidermann J. Does acute rejection correlate with the development of transplant coronary artery disease? A multicenter study using intravascular ultrasound. Sandoz/CVIS Investigators. J Heart Lung Transplant 1995;14:S221-6. 34. Yeung AC, Davis SF, Hauptman P, Kobashigawa JA, Miller LW, Valantine HA, Ventura HO, Wiedermann J, Wilensky R. Incidence and progression of transplant coronary artery disease over 1 year: results of a multicenter trial with use of intravascular ultrasound. Multicenter Intravascular Ultrasound Transplant Study Group. J Heart Lung Transplant 1995;14:S215-20. 35 CURRICULUM VITAE JON KOB ASHIGAWA, MD 35. Johnson JA, Kobashigawa JA. Methodology of quantitating intracoronary ultrasound. J Am Coll Cardiol 1995;26:303-4. 36. Miller L, Kobashigawa J, Valantine H, Ventura H, Hauptman P, O'Donnell J, Wiedermann J, Yeung A. The impact of cyclosporine dose and level on the development and progression of allograft coronary disease. Sandoz/CVIS Investigators. J Heart Lung Transplant 1995;14:S227-34. 37. Johnson JA, Kobashigawa JA. Quantitating serial intracoronary ultrasound. Circulation 1995;92:3363-4. 38. Drinkwater DC, Rudis E, Laks H, Ziv E, Marino J, Stein D, Ardehali A, Aharon A, Moriguchi J, Kobashigawa J. University of Wisconsin solution versus Stanford cardioplegic solution and the development of cardiac allograft vasculopathy. J Heart Lung Transplant 1995;14:891-6. 39. Kobashigawa JA, Laks H, Drinkwater DC, Hamilton MA, Moriguchi JD, Fonarow G, Blitz A, Hage A, Kawata N. The University of California at Los Angeles experience in heart transplantation. Clin Transpl 1995;129-35. 40. Kobashigawa JA. Letter to the Editor: Drugs in Cardiac Transplantation. N Engl J Med 1996. 41. Kobashigawa JA. Early and late complications in the elderly heart transplant recipient. (Review article). Cardiology in the Elderly 1996;4:15-21. 42. Kobashigawa JA. Coronary artery disease in the transplanted heart: What causes it and what can we do about it? Cardiology in Review 1996;4:216-25. 43. Kobashigawa JA, Sabad A, Drinkwater DC, Cogert GA, Moriguchi JD, Kawata N, Hamilton MA, Hage A, Terasaki P, Laks H. Pretransplant panel reactive-antibody screens: Are they truly a marker for poor outcome after cardiac transplantation? Circulation 1996;94:II294-7. 44. Drinkwater DC, Laks H, Blitz A, Kobashigawa J, Sabad A, Moriguchi J, Hamilton M. Outcomes of patients undergoing transplantation with older donor hearts. J Heart Lung Transplant 1996;15:684-91. 45. Katznelson S, Wilkinson AH, Kobashigawa JA, Wang XM, Chia D, Ozawa M, Zhong HP, Hirata M, Cohen AH, Terasaki PI, Danovitch G. The effect of pravastatin on acute rejection after kidney transplantation--a pilot study. Transplantation 1996;61:1469-74. 46. Johnson C, Takemoto SK, Cecka JM, Kobashigawa JA, Terasaki PI. Detection of cardiac allograft rejection for Flow Cytometry. Hum Immunology 1997;55:suppl 67. 47. Kofoed KF, Czernin J, Johnson J, Kobashigawa J, Phelps ME, Laks H, Schelbert HR. Effects of cardiac allograft vasculopathy on myocardial blood flow, vasodilator capacity, and coronary vasomotion. Circulation 1997;95:600-6. 48. Kobashigawa JA, Kasiske BL. 1997;63:331-8 (review). 49. Leaf DA, Kobashigawa J, Gleeson M, Laks H. Defining obesity in patients undergoing orthotopic heart transplantation: body mass index versus percent body fat. J Heart Lung Transplant 1997; 16:563-5. 50. Kobashigawa JA. Targeting non-alloimmune dependent pathways. Transplant Proc 1997;29(8A):47S-50S (review). 51. Kobashigawa JA. Treatment of non-hemodynamic compromising rejection: conventional approaches vs. individualization/new immunosuppressive drugs. Transplant Proc 1997;29(8A):37S-39S (review). 52. Laks H, Scholl FG, Drinkwater DC, Blitz A, Hamilton M, Moriguchi J, Fonarow GC, Kobashigawa J. The alternate recipient list for heart transplantation: does it work? J Heart Lung Transplant 1997;16:73542. 53. Johnson MR, Naftel DC, Hobbs RE, Kobashigawa JA, Pitts DE, Levine TB, Tolman D, Bhat G, Kirklin JK, Bourge RC. The incremental risk of female sex in heart transplantation: a multi-institutional Hyperlipidemia in solid organ transplantation. 36 Transplantation CURRICULUM VITAE JON KOB ASHIGAWA, MD study of peripartum cardiomyopathy and pregnancy. Cardiac Transplant Research Database Group. J Heart Lung Transplant 1997;16:801-12. 54. Wang XM, Zhong HP, Takemoto SK, Kobashigawa J, Cecka JM, Terasaki PI. A bioassay that measures sensitivity of resistance to immunosuppression. Hum Immunology 1998;59:suppl 113. 55. Kobashigawa JA, Miller L, Renlund DG, Mentzer R, Alderman E, Bourge R, Costanzo M, Eisen H, Dureau G, Ratkovec R, Hummel M, Ipe D, Johnson J, Keogh A, Mamelok R, Mancini D, Smart F, Valantine H. A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients. Mycophenolate Mofetil Investigators. Transplantation 1998;66(4):507-15. 56. Kobashigawa JA, Laks H, Marelli D, Moriguchi JD, Hamilton MA, Fonarow G, Hage A, Kawata N. The University of California at Los Angeles experience in heart transplantation. Clin Transpl 1998;:30310. 57. Katznelson S, Wang XM, Chia D, Ozawa M, Zhong HP, Hirata M, Terasaki PI, Kobashigawa JA. The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vivo. J Heart Lung Transplant 1998;17:335-40. 58. Kobashigawa JA. Mycophenolate mofetil in cardiac transplantation. Curr Opin Cardiol 1998;13:117-21. 59. Navab M, Hama SY, Van Lenten BJ, Hough GP, Hedrick CC, Sorenson R, La Du BN, Kobashigawa JA, Fonarow GC, Berliner JA, Laks H, Fogelman AM. High density associated enzymes: their role in vascular biology. Curr Opin Cardiol 1998;9:449-56. 60. Kobashigawa JA. 1998;10:155-74. 61. Kobashigawa JA. Controversies in heart and lung transplantation immunosuppression: tacrolimus versus cyclosporine. Transplant Proc 1998;30:1095-7. 62. Gebel HM, Takemoto SK, Mancini M, Costanzo MR, Kobashigawa JA, Roggero AL, Ortegal JW, Cecka JM, Tambur AR. Pre and post-transplant detection of class I and class II antibodies to predict cardiac allograft rejection. Hum Immunology 1999;60:s14. 63. Kobashigawa JA, Leaf DA, Lee N, Gleeson M, Liu H, Hamilton MA, Moriguchi JD, Kawata N, Einhorn K, Herlihy E, Laks H. A controlled trial of exercise rehabilitation after heart transplantation. N Engl J Med 1999 Jan;340:272-7. 64. Allen-Auerbach M, Schoder H, Johnson J, Kofoed K, Einhorn K, Phelps ME, Kobashigawa J, Czernin J. Relationship between coronary function by positron emission tomography and temporal changes in morphology by intravascular ultrasound (IVUS) in transplant recipients. J Heart Lung Transplant 1999;18:211-19. 65. Kobashigawa JA. Postoperative management following heart transplantation. Transpl Proc 1999;31:2038-46. 66. Son R, Tobis JM, Yeatman LA, Johnson JA, Wener LS, Kobashigawa JA. Does use of intravascular ultrasound accelerate arteriopathy in heart transplant recipients? Am Heart J 1999;138:358-63. 67. Dulai G, Higa L, Kobashigawa J, Martin P. Successful use of lamivudine for severe acute hepatitis B virus infection in a cardiac transplant recipient. Transplantation 1999;67:1288-9. 68. Skotzko CE, Rudis R, Kobashigawa JA, Laks H. Psychiatric disorders and outcome following cardiac transplantation. J Heart Lung Transplant 1999;18:952-6. 69. Kobashigawa JA. Treatment of Hyperlipidemia for the Primary Care Physician. Family Practice Recertification 2000;23:69-88. 70. Hillel Laks, MD, Daniel Marelli, MD, Daniel Fazio, DS, Jon Kobashigawa, MD. Expanding the heart donor base. Curr Opin Organ Transplant 2000;5:134-38. Advances in immunosuppression for heart transplantation. 37 Adv Card Surg CURRICULUM VITAE JON KOB ASHIGAWA, MD 71. Marelli D, Laks H, Fazio D, Moore S, Moriguchi J, Kobashigawa J. The use of donor hearts with left ventricular hypertrophy. J Heart Lung Transplant 2000;19:496-503. 72. Michaels PJ, Kobashigawa JA, Child JS, Fishbein MC. Chronic right-sided myocarditis mimicking arrhythmogenic right ventricular dysplasia. Hum Pathol 2000;31:618-21. 73. Kobashigawa J, Wener L, Johnson J, Currier JW, Yeatman L, Cassem J, Tobis J. Longitudinal Study of Vascular Remodeling in Coronary Arteries After Heart Transplantation. J Heart Lung Transplant 2000;19:546-50. 74. Cui G, Kobashigawa J, Chung T, Sen L. Atrial conduction disturbance as an indicator of rejection after cardiac transplantation. Transplantation 2000;70:223-7. 75. Tambur R, Bray RA, Takemoto SK, Mancini M, Costanzo MR, Kobashigawa JA, D'Amico CL, Kanter KR, Berg A, Vega, JD, Smith AL, Roggero AL, Ortegel JW, Hosey LW, Cecka JM, Gebel HM. Flow cytometric detection of class I and class II antibodies as a predictor of heart allograft rejection. Transplantation 2000;70:1055-59. 76. Marelli D, Laks H, Bresson J, Houston E, Fazio D, Tsai FC, Hamilton M, Moriguchi J, Fonarow GC, Ardehali A, Camara R, Burch C, Alejos JC, George B, Kawata N, Kobashigawa J. Sixteen-year experience with 1,000 heart transplants at UCLA. Clin Transpl. 2000; 297-310. 77. Kobashigawa J. What is the optimal prophylaxis for treatment of cardiac allograft vasculopathy? Curr Control Trials Cardiovasc Med 2000;1(3):166-171. 78. Ardehali A, Hughes K, Sadeghi A, Esmailian F, Marelli D, Moriguchi J, Hamilton MA, Kobashigawa J, Laks H. Inhaled nitric oxide for pulmonary hypertension after heart transplantation. Transplantation 2001; 4: 638-641. 79. Wong C, Ganz P, Miller L, Kobashigawa J, Schwarzkopf A, Valantine von Kaeper H, Wilensky R, Ventura H, Yeung AC. Role of vascular remodeling in the pathogenesis of early transplant coronary artery disease: A multicenter prospective intravascular ultrasound study. J Heart Lung Transplant. 2001 Apr;20(4):385-92. 80. Michaels PJ, Kobashigawa J, Laks H, Azarbal A, Espejo ML, Chen L, Fishbein MC. Differential expression of RANTES chemokine, TGF- and leukocyte phenotype in acute cellular rejection and Quality B lesions. J Heart Lung Transplant 2001 Apr;20(4):407-16. 81. Kobashigawa J. Research under the United Network for Organ Sharing in the United States. The Circulation Frontier 2001; 5:45. 82. Kobashigawa JA. Statins as Immunosuppressive Agents. Liver Transpl 2001 Jun;7(6):559-61. 83. Cui G, Tung T, Kobashigawa J, Laks J, Sen L. Increased incidence of atrial flutter associated with the rejection of heart transplantation. Am J Cardiol. 2001 Aug 1:88(3):280-4. 84. Rose ML, Smith J, Dureau G, Keogh A, Kobashigawa J. Mycophenolate mofetil decreases antibody production after cardiac transplantation. J Heart Lung Transplant 2002 Feb;21(2):282-5. 85. Marelli D, Bresson J, Laks H, Kubak B, Fonarow G, Tsai FC, Tran J, Weston SR, Kobashigawa J. Hepatitis C-positive donors in heart transplantation. Am J Transplant. 2002 May;2(5):443-7. 86. Fairhurst RM, Kubak BM, Pegues DA, Moriguchi JD, Ha KF, Haley JC, Kobashigawa JA. Mycobacterium haemophilum infections in heart transplant recipients: case report and review of the literature. Am J Transplant. 2002 May;2(5);476-9. 87. Tsai FC, Marelli D, Bresson J, Gjertson D, Kermani R, Patel J, Kobashigawa JA, Laks H. Use of hearts transplanted from donors with atraumatic intracranial bleeds. J Heart Lung Transplant. 2002 Jun; 21(6):623-8. 88. Boston AD, Brown RS Jr., Chavers BM, Coffman TM, Cosio FG, Colver K, Cutis JJ, Danovitch GM, Everson GT, First MR, Garvey C, Grimm R, Hertz MI, Hricik DE, Hunsicker LG, Ibrahim H, Kasiske 38 CURRICULUM VITAE JON KOB ASHIGAWA, MD BL, Kennedy M, Klag M, Knatterrud ME, Kobashigawa J, Lake JR, Light JA, Matas AJ, McDiarmid SV, Miller LW, Payne WD, Rosenson R, Sutherland DE, Tejani A, Textor S, Valantine HA, Wiesner RH. Prevention of post-transplant cardiovascular disease—report and recommendations of an ad hoc group. Am J Transplant. 2002 Jul;2(6):491-500. 89. Tsai FC, Marelli D, Bresson J, Gjertson D, Kermani R, Ardehali A, Esmailiam F, Hamilton M, Fonarow GC, Moriguchi J, Plunkett M, Hage A, Tran J, Kobashigawa JA, Laks H. Recent trends in early outcome of adult patients after heart transplantation: a single-institution review of 251 transplants using standard donor organs. Am J Transplant. 2002 Jul;2(6):539-45. 90. Pinderski LJ, Fonarow GC, Hamilton M, Fishbein MC, Marelli D, Moriguchi J, Cohen B, Kobashigawa JA. Giant cell myocarditis in a young man responsive to T-lymphocyte cytolytic therapy. J Heart Lung Transplant. 2002 Jun;21(6):818-21. 91. Takano Y, Currier J, Yeatman L, Kobashigawa JA, Rogers A, Cianfichi L, Fishbein MC, Tobis JM. Cutting Balloon Angioplasty for Cardiac Transplant Vasculopathy. J Heart Lung Transplant 2002 Aug;21(8) 910-913. 92. Tsai FC, Marelli D, Laks H, Moriguchi J, Sohper M, Bresson J, Moghaddam S, Kubak B, Esmailian F, Ardehali A, Plunkett M, Litwin P, Kobashigawa J. Short-term bridge to heart transplant using the BVS 5000 external ventricular assist device. Am J Transplant. 2002 Aug;2(7):646-51. 93. Marelli D, Laks H, Kobashigawa JA, Bresson J, Ardehali A, Esmailian F, Plunkett MD, Kubak B. Seventeen-Year Experience with 1,083 Heart Transplants at a Single Institution. Society Thorac Surg. 2002;74:1558-67. 94. Michaels PJ, Espejo ML, Kobashigawa J, Alejos JC, Burch C, Takemoto S, Reed EF, Fishbein MC. Humoral Rejection in Cardiac Transplantation: Risk Factors, Hemodynamic Consequences and Relationship to Transplant Coronary Artery Disease. J Heart Lung Transplant. 2003 Jan; 22(1): 58-69. 95. Deng MC, Young JB, Stevenson LW, Oz MC, Rose EA, Hunt SA, Kirklin JK, Kobashigawa J, Miller L, Saltzberg M, Konstam M, Portner PM, Kormos R. Destination mechanical circulatory support: proposal for clinical standards. J Heart Lung Transplant. 2003 Apr; 22(4):365-9. 96. Gajjar N, Kobashigawa JA, Laks H, Espejo-Vassilakis M, Fishbein MC. FK506 versus cyclosporin: Pathologic findings in 1067 endomyocardial biopsies. Cardiovasc Pathol. 2003 Apr; 12:73-76. 97. Marelli D, Kermani R, Bresson, J, Fishbein MC, Hamilton M, Moriguchi J, Fonarow GC, Cohen B, Kobashigawa JA, Laks H. Support with the BVS 5000 Assist Device during Treatment of Acute Giant-Cell Myocarditis. Tex Heart Inst J. 2003;30(1):50-6. 98. Laks H, Marelli D, Fonarow GC, Hamilton MA, Ardehali A, Moriguchi JD, Bresson J, Gjertson D, Kobashigawa JA. Use of two recipient lists for adults requiring heart transplantation. J Thorac Cardiovasc Surg 2003;125(1):49-59. 99. Eisen HJ, Tuzcu EM, Dorent R, Kobashigawa JA, Mancici D, Valentine-von Kaeppler HA, Starling RC, Sorensen K, Hummel M, Lind JM, Abeywickrama KH, Bernhardt, P. Everolimus for the Prevention of Allograft Rejection and Vasculopathy in Cardiac Transplant Recipients. N Engl J Med 2003; 349:847-58. 100. Kao J, Kobashigawa J, Fishbein MC, MacLellan WR, Burdick MD, Belperio JA, Strieter RM. Elevated serum levels of the CXCR3 chemokine ITAC are associated with the development of transplant coronary artery disease. Circulation 2003;107(15):1958-61. Epub 2003 Apr 14. 101. Evangelista LS, Doering LV, Dracup K, Vassilakis ME, Kobashigawa J. Hope, mood states and quality of life in female heart transplant recipients. J Heart Lung Transplant 2003;22(6):681-6. 102. Cui G, Kobashigawa J, Margarian A, Sen L. Cause of atrioventricular block in patients after heart transplantation. Transplantation 2003;76(1):137-42. 103. Kobashigawa JA. First-year intravascular ultrasound results as a surrogate marker for outcomes after heart transplantation. J Heart Lung Transplant 2003;22(7):711-4. Review. 39 CURRICULUM VITAE JON KOB ASHIGAWA, MD 104. Radovancevic B, McGiffin DC, Kobashigawa JA, Cintron GB, Mullen GM, Pitts DE, O'Donnell J, Thomas C, Bourge RC, Naftel DC. Retransplantation in 7,290 primary transplant patients: a 10-year multi-institutional study. J Heart Lung Transplant 2003;22(8):862-8. 105. Grise MA, Reilly JP, Tobis JM, Takano Y, Currier JW, Kobashigawa JA, Weisz G, Moses JW, Leon MB, Yeung A, Teirstein PS. Intracoronary radiation to treat in-stent restenosis in six cardiac transplant patients. Catheter Cardiovasc Interv 2003;60(1):41-4. 106. Marelli D, Laks H, Patel B, Kermani R, Marmureanu A, Patel J, Kobashigawa J; University of California at Los Angeles Heart Transplant Group. Heart transplantation in patients with diabetes mellitus in the current era. J Heart Lung Transplant 2003;22(10):1091-7. 107. Marelli D, Laks H, Bresson S, Ardehali A, Bresson J, Esmailian F, Plunkett M, Moriguchi J, Kobashigawa J. Results after transplantation using donor hearts with preexisting coronary artery disease. J Thorac Cardiovasc Surg 2003;126(3):821-5. 108. Evangelista LS, Moser D, Dracup K, Doering L, Kobashigawa J. Functional status and perceived control influence quality of life in female heart transplant recipients. J Heart Lung Transplant 2004;23(3):360-7. 109. Sung EC, Friedlander AH, Kobashigawa JA. The prevalence of calcified carotid atheromas on the panoramic radiographs of patients with dilated cardiomyopathy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97(3):404-7. 110. Patel JK, Kobashigawa JA. Cardiac transplant experience with cyclosporine. Transplant Proc 2004;36(2 Suppl):323S-330S. 111. Patel JK, Kobashigawa JA. Cardiac transplantation: the alternate list and expansion of the donor pool. Curr Opin Cardiol 2004;19(2):162-5. 112. Fishbein MC, Kobashigawa J. Biopsy-negative cardiac transplant rejection: etiology, diagnosis, and therapy. Curr Opin Cardiol 2004;19(2):166-9. 113. Reyes CJ, Evangelista LS, Doering L, Dracup K, Cesario DA, Kobashigawa J. Physical and psychological attributes of fatigue in female heart transplant recipients. J Heart Lung Transplant 2004;23(5):614-9. 114. Kobashigawa JA. Statins in solid organ transplantation: is there an immunosuppressive effect? Am J Transplant 2004;4(7):1013-8. 115. Takemoto SK, Zeevi A, Feng S, Colvin RB, Jordan S, Kobashigawa J, Kupiec-Weglinski J, Matas A, Montgomery RA, Nickerson P, Platt JL, Rabb H, Thistlethwaite R, Tyan D, Delmonico FL. National conference to assess antibody-mediated rejection in solid organ transplantation. Am J Transplant 2004;4(7):1033-41. 116. Chantranuwat C, Blakey JD, Kobashigawa JA, Moriguchi JD, Laks H, Espejo Vassilakis M, Fishbein MC. Sudden, unexpected death in cardiac transplant recipients: An autopsy study. J Heart Lung Transplant 2004;23:683-9. 117. Phillips M, Boehmer JP, Cataneo RN, Cheema T, Eisen HJ, Fallon JT, Fisher PE, Gass A, Greenberg J, Kobashigawa J, Mancini D, Rayburn B, Zucker MJ. Heart allograft rejection: detection with breath alkanes in low levels (the HARDBALL Study). J Heart Lung Transplant 2004;23:701-8. 118. Mehra MR, Kobashigawa JA. Advances in heart and lung transplantation 2004: report from the 24th International Society for Heart and Lung Transplantation annual meeting, San Francisco, April 21-24, 2004. J Heart Lung Transplant 2004;23(8):925-30. 119. Kobashigawa JA. Presidential Address: “International Camaraderie”—Excerpts from the ISHLT 2004 presidential address. J Heart Lung Transplant 2004;23(8):931-2. 40 CURRICULUM VITAE JON KOB ASHIGAWA, MD 120. Lindenfeld J, Miller GG, Shakar SF, Zoltry R, Lowes BD, Wolfel EE, Mestroni L, Page RL, Kobashigawa, J. Drug therapy in the heart transplant recipient. Part I: cardiac rejection and immunosuppressive drugs. Circulation 2004;110(24):3734-3740. 121. Phillips M, Boehmer JP, Cataneo RN, Cheema T, Eisen HJ, Fallon JT, Fisher PE, Gass AG, Greenberg J, Kobashigawa J, Mancini D, Rayburn B, Zucker MJ. Prediction of heart transplant rejection with a breath test for markers of oxidative stress. Am J Cardiol 2004;1593-4. 122. Kobashigawa JA. Editorial Overview: Is it time for a noninvasive test to detect cardiac allograft rejection? Curr Opin Organ Transplant 2004, 9:441-2. 123. Lindenfeld J, Miller GG, Shakar SF, Zoltry R, Lowes BD, Wolfel EE, Mestroni L, Page RL, Kobashigawa, J. Drug therapy in the heart transplant recipient. Part II: common medical problems and drug-drug interactions. Circulation 2004;111(25):3858-65. 124. Patel J and Kobashigawa JA. Immunosuppression, Diagnosis and Treatment of Cardiac Allograft Rejection. Semin Thorac Cardiovasc Surg 2004;16(4):378-385. 125. Subherwal S, Kobashigawa JA, Cogert G, Patel J, Espejo M, Oeser B. Incidence of acute cellular rejection and non-cellular rejection. Transplant Proc 2004;36(10):3171-2. 126. Kobashigawa JA. Statins and cardiac allograft vasculopathy Semin Vasc Med. 2004 Nov;4(4):401-6. 127. Eisen H, Kobashigawa J, Starling RC, Valantine H, Mancini D. Improving outcomes in heart transplantation – the potential of proliferation signal inhibitors. Transplant Proc 2005;37(Suppl 4S):4S17S. 128. Kobashigawa JA, Tobis JM, Starling RC, Tuzcu EM, Smith AL, Valantine HA, Yeung AC, Mehra MR, Anzai H, Oeser BT, Abeywickrama KH, Murphy J, Cretin N. Multicenter Intravascular Ultrasound (IVUS) Validation Study Among Heart Transplant Recipients: Outcomes After 5 Years. J Am College of Cardiology 2005 May 3;45(9):1532-1537. 129. Kobashigawa J, David K, Morris J, Chu AH, Steffen BJ, Gotz VP, Gordon RD. Daclizumab is associated with decreased rejection and no increased mortality in cardiac transplant patients receiving MMF, cyclosporine and corticosteroids. Transplant Proc 2005;37:1333-39. 130. Evans RW, Willaims GE, Baron HM, Deng MC, Eisen HJ, Hunt SA, Khan MM, Kobashigawa JA, Marton EN, Mehra MR, Mital SR. The economic implication of noninvasive molecular testing for cardiac allograft rejection. Am J Transplant 2005;5:1553-1558. 131. Eisen HJ, Kobashigawa J, Keogh A, Bourge R, Renlund D, Mentzer R, Alderman E, Valantine H, Dureau G, Mancinin D, Mamelok R, Gordon R, Wang W, Mehra M, Constanzo MR, Hummel M, Johnson J, Mycophenolate Mofetil Cardiac Study Investigators. Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients. J Heart Lung Transplant. 2005;24(5):517-25. 132. Patel JK, Kobashigawa JA. Immunosuppressants in cardiac transplantation. Hosp Pharm Europe 2005 May/June. 133. Mitropoulos FA, Odim J, Marelli D, Karandikar K, Gjertson D, Ardehali A, Kobashigawa J, Laks H. Outcome of hearts with cold ischemic time greater than 300 minutes. A case-matched study. Eur J Cardiothorac Surg. 2005 Jul;28(1):143-8. 134. Grady K, Naftel D, White-Williams C, Bellg A, Young J, Pelegrin D, Patton-Schroeder K, Kobashigawa J, Chait J, Kirklin J, Piccione Jr. W, McLeod M, Heroux A. Predictors of Quality of Life at 5 to 6 Years after Heart Transplantation. J Heart Lung Transplant 2005. 2005 Sep;24(9):1431-9. 135. Evangelista LS, Dracup K, Doering L, Moser DK, Kobashigawa J. Physical Activity Patterns in Heart Transplant Women. J Cardiovasc Nurs. 2005 September/October;20(5):334-339. 41 after heart transplantation. CURRICULUM VITAE JON KOB ASHIGAWA, MD 136. Kobashigawa JA, Meiser BM. Review of major clinical trials with mycophenolate mofetil in cardiac transplantation. Transplantation. 2005 Oct 15;80(2 Suppl):S235-43. 137. Kobashigawa JA, Moriguchi JD, Laks H, Wener L, Hage A, Hamilton MA, Cogert G, Marguez A, Vassilakis ME, Patel J, Yeatman L. Ten-Year Follow-up of a Randomized Trial of Pravastatin in Heart Transplant Patients. J Heart Lung Transplant 2005. Nov;24(11):1736-40. 138. Stewart S, Winters GL, Fishbein MC, Tazelaar HD, Kobashigawa J, Abrams J, Andersen CB, Angelini A, Berry GJ, Burke MM, Demetris AJ, Hammond E, Itescu S, Marboe CC, McManus B, Reed EF, Reinsmoen NL, Rodriguez ER, Rose AG, Rose M, Suciu-Focia N, Zeevi A, Billingham ME. Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant. 2005 Nov;24(11):1710-20. 139. Billingham M, Kobashigawa J. Editorial: The revised ISHLT Heart Biopsy Grading Scale. J Heart Lung Transplant 2005. J Heart Lung Transplant. 2005 Nov;24(11):1709. 140. Grady KL, Naftel DC, Kirklin J, White-Williams C, Kobashigawa J, Chait J, Young J, Pelegrd, Rybarczyk B, Heroux A. Predictors of physical functional disability at 5-6 years after heart transplantation. J Heart Lung Transplant 2005 Dec;24(12):2279-85. 141. Deng MC, Eisen HJ, Mehra MR, Billingham M, Marboe CC, Berry G, Kobashigawa J, Johnson FL, Starling RC, Murali S, Pauly DF, Baron H, Wohlgemuth JG, Woodward RN, Klingler TM, Walther D, Lal PG, Rosenberg S, Hunt S; CARGO Investigators. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am J Transplant. 2006 Jan;6(1):150-60. 142. Reed EF, Demetris AJ, Hammond E, Itescu S, Kobashigawa JA, Reinsmoen NL, Rodriguez E R, Rose M, Stewart S, Suciu-Foca N, Zeevi A, Fishbein MC. Acute Antibody-mediated Rejection of Cardiac Transplants. J Heart Lung Transplant. 2006 Feb;25(2):153-159. 143. Odim J, Wheat J, Laks H, Kobashigawa J, Gjertson D, Osugi A, Mukherjee K, Saleh S. Peri-operative Renal Function and Outcome after Orthotopic Heart Transplantation. J Heart Lung Transplant. 2006 Feb;25(2):162-66. 144. Patel JK, Kobashigawa JA. Should we be doing routine biopsy after heart transplantation in a new era of anti-rejection? Curr Opin Cardiol. 2006 Mar;21(2):127-31. 145. Kobashigawa JA, Patel J. Review: Immunosuppression for heart transplantation: where are we now? Nat Clin Pract Cardiovasc Med. 2006;3(4):203-12. 146. Kobashigawa JA, Patel J, Furukawa H, Moriguchi JD, Yeatman L, Takemoto S, Marquez A, Shaw J, Oeser BT, Subherwal S, Wu GW, Kawano J, Laks H. Five-Year Results of a Randomized Single Center Study of Tacrolimus Versus Micoremulsion Cyclosporine in Heart Transplant Patients. J Heart and Lung Transplant 2006;25(4):434-9. 147. Li HY, Tanaka K, Oeser B, Wertman B, Kobashigawa JA, Tobis JM. Compensatory enlargement in transplant coronary artery disease: an intravascular ultrasound study. Chin Med J (Engl). 2006 Apr 5;119(7):564-9. 148. Tanaka K, Li H, Curran PJ, Takano Y, Arbit B, Currier JW, Yeatman LA, Kobashigawa JA, Tobis JM. Usefulness and Safety of Percutaneous Coronary Interventions for Cardiac Transplant Vasculopathy. Am J Cardiol. 2006 Apr 15;97(8):1192-7. 149. Kobashigawa JA, Tobis JM, Mentzer RM, Valantine HA, Bourge RC, Mehra R, Smart FW, Miller LW, Tanaka K, Haiyan L, Gjertson DW, and Gordon RD. Mycophenolate mofetil reduces intimal thickness by intravascular ultrasound after heart transplantation: reanalysis of the multicenter trial. Am J Transplant 2006;6(5 Pt. 1):993-7. 150. Kobashigawa JA, Miller LW, Russell SD, Ewald GA, Zucker M, Goldberg LR, Eisen HJ, Salm K, Tolzman D, Gao J, Fitzsimmons WE, First R.. Tacrolimus with Mycophenolate Mofetil (MMF) or Sirolimus vs. Cyclosporine with MMF in Cardiac Transplant Patients: 1-Year Report. Am J Transplant 2006;6(6):1377-86. 42 CURRICULUM VITAE JON KOB ASHIGAWA, MD 151. Li H, Tanaka K, Anzai H, Oeser B, Lai D, Kobashigawa JA, Tobis JM. Influence of pre-existing donor atherosclerosis on the development of cardiac allograft vasculopathy and outcomes in heart transplant recipients. J Am Coll Cardiol 2006;47(12):2470-6. 152. Patel JK, Kobashigawa JA. Everolimus: an immunosuppressive agent in transplantation. Expert Opin Pharmacother 2006;7(10):1347-55. 153. Lepin EJ, Zhang Q, Zhang X, Jindra PT, Hong LS, Ayele P, Peralta MV, Gjertson DW, Kobashigawa JA, Wallace WD, Fishbein MC, Reed EF. Phosphorylated S6 Ribosomal Protein: A Novel Biomarker of Antibody Mediated Rejection in Heart Allografts. Am J Transplant 2006;6(7):1560-71. 154. Kobashigawa, JA. Cardiac Allograft Vasculopathy in Heart Transplant Patients: Pathologic and Clinical Aspects for Angioplasty/Stenting. Editorial Comment. J Am Coll Cardiol 2006 Aug;48(3):462-3. 155. Kobashigawa JA, Renlund DG, Gerosa G, Almenar, Eisen HJ, Keogh AM, Lehmkuhl HB, Livi U, Ross H, Segovia J, Yonan, Novartis Reps. A 12 month, single blind, randomized, parallel group, multicenter study, to investigate the efficacy and safety of enteric coated mycophenolate sodium (ECMPS) compared with mycophenolate mofetil (MMF) in de novo heart recipients: 12 month results. J Heart Lung Transplant 2006; 25(8):935-41. 156. Li H, Tanaka K, Oeser B, Lai D, Kobashigawa JA, Tobis JM. Vascular remodeling after cardiac transplantation: a 3-year serial intravascular ultrasound study. Eur Heart J 2006; 27(14):1671-7. 157. Mehra MR, Kobashigawa J, Starling R, Russell S, Uber PA, Parameshwar J, Mohacsi P, Augustine S, Aaronson K, Barr M. Listing criteria for heart transplantation: International Society for Heart and Lung Transplantation guidelines for the care of cardiac transplant candidates--2006. J Heart Lung Transplant. 2006;25(9):1024-42. 158. Kobashigawa JA, Starling R, Mehra M, Kormos R, Bhat G, Barr M. Multi-center Retrospective Analysis of Cardiovascular Risk Factors Affecting Outcome of De Novo Cardiac Transplant Recipients. J Heart Lung Transplant. 2006 Sep;25(9):1063-9. 159. Starling RC, Pham M, Valantine H, Miller L, Eisen H, Rodriguez ER, Taylor DO, Yamani MH, Kobashigawa J, McCurry K, Marboe C, Mehra MR, Zuckerman A, Deng MC; Working Group on Molecular Testing in Cardiac Transplantation. Molecular testing in the management of cardiac transplant recipients: initial clinical experience. J Heart Lung Transplant. 2006;25(12):1389-95. 160. Li H, Tanaka K, Chhabra A, Oeser B, Kobashigawa JA, Tobis JM.Vascular Remodeling 1 Year After Cardiac Transplantation. J Heart Lung Transplant. 2007 Jan;26(1):56-62. 161. Patel JK, Kobashigawa JA. Tacrolimus in Cardiac Transplantation. Expert Review of Clinical Immunology 2007:3(2):131-8. 162. Grady KL, Naftel DC, Kobashigawa J, Chait J, Young JB, Pelegrin D, Czerr J, McLeod M, Heroux A, Higgins R, White-Williams C, Kirklin JK. Patterns and predictors of quality of life at 5–10 years after heart transplantation. J Heart Lung Transplant. 2007 May;26(5):535-43. 163. Rybarczyk B, Grady KL, Naftel DC, Kirklin JK, White-Williams C, Kobashigawa J, Chait J, Young JB, Pelegrin D, Czerr J, McLeod J, Rissinger M, Higgins R, Heroux A. Emotional Adjustment Five Years after Heart Transplant: A Multi-Site Study. Rehab Psych 2006;52:206-14. 164. Barr ML, Kobashigawa JA. Improving Long-term Outcomes of Heart Transplantation: Cardiac Allograft Vasculopathy, Malignancy, and Treatment Options. Clinical Updates 2006 165. Kobashigawa JA. Contemporary Concepts in Noncellular Rejection. Heart Failure Clin 2007 Jan:3(1):11-15. 166. Patel JK, Kobashigawa JA. Tacrolimus in Heart Transplant Recipients: an overview. Biodrugs 2007:21(3):139-143. 167. De La Zerda DJ, Cohen O, Beygui RE, Kobashigawa J, Hekmat D, Laks H. Alcohol use in donors is a protective factor on recipients' outcome after heart transplantation. Transplantation. 2007;83(9):1214-8. 43 CURRICULUM VITAE JON KOB ASHIGAWA, MD 168. Hill JA, Hummel M, Starling RC, Kobashigawa JA, Perrone SV, Arizon JM, Simonsen S, Abeywickrama KH, Bara C. A Lower Incidence of Cytomegalovirus Infection in De Novo Heart Transplant Recipients Randomized to Everolimus. Transplantation 2007 Dec 15;84(11):1436-42. 169. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klinger TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ, CARGO Investigators. Transcriptional signals of T-cell and corticosteroids sensitive genes are associated with future acute cellular rejection in cardiac allografts. 2007 Dec;26(12):1255-63. 170. Bernstein D, Williams GE, Eisen H, Mital S, Wohlgemuth JG, Klinger TM, Fang KC, Deng MC, Kobashigawa J. Gene expression profiling distinguishes a molecular signature for grade 1B mild acute cellular rejection in cardiac allograft recipients. J Heart Lung Transplant 2007 Dec;26(12):1270-80. 171. Flechner SM, Kobashigawa J, Klintmalm G. Calcineurin Inhibitor-Sparing Regimens in Solid Organ Transplantation: Focus on Improving Renal Function and Nephrotoxicity. Clin Transplant 2008;22:1-15. 172. Kobashigawa JA and Patel JK. Pathophysiology for Coronary Artery Vasculopathy. Transplant Index and Reviews 2008. 173. Lieberman JR, Roth KM, Elsissy P, Dorey FJ, Kobashigawa JA. Symptomatic Osteonecrosis of the Hip and Knee After Cardiac Transplantation. J Arthroplasty 2008 Jan; 23(1):90-6. 174. Flechner SM, Kobashigawa J, Klintmalm G. Calcineurin Inhibitor Sparing Regimens in Solid Organ Transplantation: Focus on Improving Renal Function and Nephrotoxicity. Clin Transplant 2008 JanFeb;22(1):1-15. 175. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klinger TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ, CARGO Investigators. Clinical Implications and Longitudinal Alteration of Peripheral Blood Transcriptional Signals Indicative of Future Cardiac Allograft Rejection. J Heart Lung Transplant 2008 Mar; 27(3):297-301. 176. Lee MS, Kobashigawa J, Tobis J. Comparison of Percutaneous Coronary Intervention With BareMetal and Drug-Eluting Stents for Cardiac Allograft Vasculopathy J Am Coll Cardiol Intv 2008;1:710-715 177. Lehmkuhl H, Hummel M, Kobashigawa J, Ladenburger S, Rothenburger M, Sack F, Dengler T, Hetzer R. Enteric-coated mycophenolate-sodium in heart transplantation: efficacy, safety, and pharmacokinetic compared with mycophenolate mofetil. Transplantation Proceedings 2008 May;40(4):953-5. 178. Vaseghi M, Boyle NG, Kedia R et al. Supraventricular tachycardia after orthotopic cardiac transplantation. J Am Coll Cardiol 2008 Jun 10;51(23):2241-9. 179. Segovia J, Gerosa G, Almenar L, Livi U, Vigano M, Arizon JM, Yonan N, Di Salvo TG, Renlund DG, Kobashigawa JA, ERL 2401 Study Group. Impact of Dose Reductions on Efficacy Outcome in Heart Transplant Patients Receiving Enteric-Coated Mycophenolate Sodium or Mycophenolate Mofetil at 12 Months Post-Transplantation. Clin Transplant 2008 Nov-Dec;22(6):809-14. 180. Kubak BM, Gregson AL, Pegues DA, Leibowitz MR, Carlson M, Marelli D, Patel J, Laks H, Kobashigawa JA. Use of Hearts Transplanted from Donors with Severe Sepsis and Infectious Deaths. J Heart Lung Transplant 2009 Mar;28(3):260-5. 181. Kobashigawa J, Mehra M, West L, Kerman K, George J, Rose M, Zeevi A, Reinsmoen N, Patel J, Reed E, Consensus Conference Participants. Report from a Consensus Conference on the Sensitized Patient Awaiting Heart Transplantation. J Heart Lung Transplant 2009 Mar;28(3):213-25. 182. Vaseghi M, Lellouche N, Ritter H, Fonarow GC, Patel JK, Moriguchi J, Fishbein MC, Kobashigawa JA, Shivkumar K. Mode and Mechanisms of Death Following Orthotopic Heart Transplantation. Heart Rhythm 2009 Apr;6(4):503-9. 183. Wu GW, Kobashigawa JA, Fishbein MC, Patel JK, Kittleson MM, Reed EF, Kiyosaki KK, Ardehali A. Asymptomatic Antibody-Mediated Rejection After Heart Transplantation Predicts Poor Outcomes. J Heart Lung Transplant 2009 May;28(5):417-22. 44 CURRICULUM VITAE JON KOB ASHIGAWA, MD 184. Marelli D, Esmailian F, Wong SY, Kobashigawa JA, Kwon MH, Beygui RE, Laks H, Plunkett MD, Ardehali A, Shemin RJ. Tricuspid Valve Regurgitation After Heart Transplantation. J Thorac Cardiovasc Surg 2009 Jun; 137(6):1557-9. 185. Yang HM, Lai CK, Gjertson DW, Baruch-Oren T, Ra SH, Watts W, Wallace WD, Shintaku P, Kobashigawa JA, Fishbein MC. Has the 2004 Revision of the International Society of Heart and Lung Transplantation Grading System Improved the Reproducibility of the Diagnosis and Grading of Cardiac Transplant Rejection? Cardiovasc Pathol 2009 Jul-Aug;18(4):198-204. 186. Grady KL, Wang E, Higgins R, Heroux A, Rybarczyk B, Young JB, Pelegrin D, Czerr J, Kobashigawa J, Chait J, Naftel DC, White Williams C, Myers S, Kirklin JK. Symptom Frequency and Distress from 5 to 10 years after Heart Transplantation. J Heart Lung Transplant 2009 Aug;28(8):759-68. 187. Baran DA, Taylor DO, Kobashigawa JA. Immunosuppression and Heart Transplantation: How Do We Define Success? Editorial. Am J Transplant. 2010 Feb;10(2):205-6. 188. Kobashigawa JA, Kiyosaki KK, Patel JK, Kittleson MM, Kubak BM, Davis SN, Kawano MA, Ardehali AA. The Benefit of Immune Monitoring in Heart Transplant Patients Using ATP Production in Activated Lymphocytes. J Heart Lung Transplant. 2010 May;29(5):504-8. 189. Kobashigawa JA. Non-Invasive Blood Tests Hold Promise for Transplant Outcomes. Cedars-Sinai Advances in Heart & Heart Surgery. 2010 June; 1. 190. Mehra MR, Crespo-Leiro MG, Dipchand A, Ensminger SM, Hiemann NE, Kobashigawa JA, Madsen J, Parameshwar J, Starling RC, Uber PA. International Society for Heart and Lung Transplant Working Formulation of a Standardized Nomenclature for Cardiac Allograft Vasculopathy—2010. J Heart and Lung Transplant. 2010 June;29(6): 717-27. 191. Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, Desai S, Fedson S, Fisher P, GonzalesStawinski G, Martinelli L, McGiffin D, Smith J, Taylor D, Meiser B, Webber S, Baran D, Carboni M, Dengler T, Feldman D, Frigerio M, Kfoury A, Kim D, Kobashigawa J, Shullo M, Stehlik J, Teuteberg J, Uber P, Zuckermann A, Hunt S, Burch M, Bhat G, Canter C, Chinnock R, Crespo-Leiro M, Delgado R, Dobbels F, Grady K, Kao W, Lamour J, Parry G, Patel J, Pini D, Towbin J, Wolfel G, Delgado D, Eisen H, Goldberg L, Hosenpud J, Johnson M, Keogh A, Lewis C, O'Connell J, Rogers J, Ross H, Russell S, Vanhaecke J; International Society of Heart and Lung Transplantation Guidelines. The International society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2010 Aug; 29(8):914-56 192. Oda N, Kato TS, Komamura K, Patel J, Kobashigawa JA. Retrospective Review of Japanese Heart Transplant Recipients Transplanted in Japan and Transplanted in the U.S. J Heart Lung Transplant. . 2010 Sep;29(9):1076-8. 193. Kobashigawa JA, Patel JK, Kittleson MM, Kawano MA, Kiyosaki KK, Davis SN, Moriguchi JD, Reed EF, Ardehali AA. The long-term outcome of treated sensitized patients who undergo heart transplantation. Clin Transplant. 2010 Oct; E-pub. 194. Taylor D, Meiser B, Webber S, Baran DA, Carboni M, Dengler T, Feldman D, Frigerio M, Kfoury A, Kim D, Kobashigawa J, Shullo M, Stehlik J, Teuteberg J, Uber PA, West L, Zuckermann A. ISHLT HT Guidelines Task Force 2: Immunosuppression and Rejection. J Heart Lung Transplant. 2010 Nov, Epub. 195. Kobashigawa JA. Strategies in immunosuppression after heart transplantation: is less better? Circ Heart Fail. 2011 Mar; 4(2): 111-3. 196. Kobashigawa J, Crespo-Leiro MG, Ensminger SM, Reichenspurner H, Angelini A, Berry G, Burke M, Czer L, Hiemann N, Kfoury AG, Mancini D, Mohacsi P, Patel J, Pereira N, Platt JL, Reed EF, Reinsmoen N, Rodriguez ER, Rose ML, Russell SD, Starling R, Suciu-Foca N, Tallaj J, Taylor DO, Van Bakel A, West L, Zeevi A, Zuckermann, A. Report from a consensus conference on antibody-mediated rejection in heart transplantation. J Heart Lung Transplant. 2011 Mar; 30(3): 252-69. 45 CURRICULUM VITAE JON KOB ASHIGAWA, MD 197. Lockhart D, Kittleson MM, Velleca A, Patel JK, Kobashigawa JA. Homeless donors and heart transplantation outcomes. J Heart Lung Transplant. 2011 Mar; 30(3): 355-6. 198. Kittleson MM, Kobashigawa JA. Management of advanced heart failure: the role of heart transplantation. Circulation. 2011 Apr; 123(14): 1569-74. 199. Zhang Q, Cecka JM, Gjertson DW, Ge P, Rose ML, Patel JK, Ardehali A, Kobashigawa JA, Fishbein MC, Reed EF. HLA and MICA: targets of antibody-mediated rejection in heart transplantation. Transplantation. 2011 May; 91(10): 1153-1158. ***“Editor’s Pick” 200. Patel J, Kobashigawa J. Quest for lower immunosuppression in cardiac transplantation: an analysis of the TICTAC trial. Future Cardiol. 2011 May;7(3):293-7. 201. Liu T, Shehata M, Chang D, Patel J, Kittleson M, Kobashigawa J, Chugh SS, Wang X. Prolonged QT and cardiac arrest post heart transplantation: inherited or acquired? J Electrocardiol. 2011 May-Jun; 44(3): 350-2. 202. Patel JK, Kittleson M, Kobashigawa JA. Cardiac Allograft Rejection. Surgeon. 2011 Jun; 9 (3): 160-167. 203. Berry GJ, Angelini A, Burke MM, Bruneval P, Fishbein MC, Hammond E, Miller D, Neil D, Revelo MP, Rodriguez ER, Stewart S, Tan C, Winters G, Kobashigawa J, Mehra MR. The ISHLT working formulation for pathological diagnosis Of antibody-mediated rejection in heart transplantation: evolution and current status (2005-2011). J Heart Lung Transplant. 2011 Jun; 30(6):601-11. 204. Patel J, Kobashigawa J. Everolimus for Cardiac Allograft Vasculopathy – Every Patient, at any Time? Transplantation. 2011 Jul 27; 92(2): 127-128. 205. Patel JK, Kobashigawa JA. Cardiology patient page: Heart transplantation. Circulation. 2011 Jul 26; 124(4):e132-4. 206. Kittleson M, Shemin R, Patel J, Ardehali A, Kawano M, Davis S, Moriguchi J, Kobashigawa J. Donorrecipient sex mismatch portends poor 10-year outcomes in a single-center experience. J Heart Lung Transplant. 2011 Sept; 30(9): 1018-1022. 207. Lu WH, Palatnik K, Fishbein GA, Lai C, Levi DS, Perens G, Alejos J, Kobashigawa J, Fishbein MC. Diverse morphologic manifestations of cardiac allograft vasculopathy: A pathologic study of 64 allograft hearts. J Heart Lung Transplant. 2011 Sept; 30(9): 1044-1050. 208. Moriguchi J, Davis S, Jocson R, Esmailian F, Ardehali A, Laks H, Kwon M, Kittleson M, Kobashigawa J, Patel J, Marelli D, Plunkett M, Beygui R, Shemin R. Successful use of a pneumatic biventricular assist device as a bridge to transplantation in cardiogenic shock. J Heart Lung Transplant. 2011 Oct; 30(10): 1143-7. 209. Kittleson MM, Patel JK, Moriguchi JD, Kawano M, Davis S, Hage A, Hamilton MA, Esmailian F, Kobashigawa JA. Heart Transplant recipients supported with extracorporeal membrane oxygenation: outcomes from a single-center experience. J Heart Lung Transplant. 2011 Nov; 30(11):1250-6. 210. Yanagida R, Czer LSC, Reinsmoen N, Cao K, Rafiei M, De Robertis MA, Mirocha J, Kass RM, Kobashigawa JA, Trento A. Impact of virtual cross match on waiting times for heart transplantation. Ann Thorac Surg: 2011 Dec; 92(6):2104-10. 211. Zuckermann A, Arizon JM, Dong G, Eisen HJ, Kobashigawa J, Lehmkuhl H, Ross H, Pelligrini C, Wang S-S, Barten MJ. Impact of De-Novo Everolimus-Based Immunosuppression on Incisional Complications in Heart Transplantation. Transplantation. 2011 Sep 15; 92(5):594-600. 212. Patel J, Everly M, Chang D, Kittleson M, Reed E, Kobashigawa J. Reduction of alloantibodies via proteasome inhibition in cardiac transplantation. J Heart Lung Transplant. 2011 Dec; 30(12): 1320-6. 213. Shah MR, Starling RC, Longacre LS, Mehra MR, Working Group Participants (Kobashigawa J). Heart Transplantation Research in the Next Decade – A Goal to Achieving Evidence-Based Outcomes. J Am Coll Cardiol. 2012 Apr 3; 59(14):1263-9. 46 CURRICULUM VITAE JON KOB ASHIGAWA, MD 214. Thajudeen A, Stecker EC, Shehata M, Patel J, Wang X, McAnulty JH Jr, Kobashigawa J, Chugh SS. Arrhythmias after Heart Transplantation: Mechanisms and management. J Am Heart Ass. 2012 Apr; 1(2):e001461. 215. Kfoury A, Kobashigawa JA. Prioritizing sensitized heart transplant candidates. A sensitize affair. J Heart Lung Transplant. 2012 Jul; 31(7):677-8. 216. Kobashigawa J, Ross H, Bara C, Delgado JF, Dengler T, Lehmkuhl HB, Wang S, Dong G, Witte S, Junge G, Potena L. Everolimus is associated with a reduced incidence of cytomegalovirus infection following de novo cardiac transplantation. Transplant Infectious Disease. 2012; 0:1-13. 217. Kobashigawa JA. The Future of Heart Transplantation. Am J of Transplant. 2012 Aug 17; Epub. 218. Shah AB, Morrissey RP, Baraghoush A, Bharadwaj P, Phan A, Hamilton M, Kobashigawa J, Schwarz ER. Failing the Failing Heart: A review of Palliative Care in Heart Failure. Rev Cardiovasc Med. 2013; 14(1): 41-48. 219. Shah AB, Patel JK, Rafiei M, Morrissey RP, Kittleson MM, Kobashigawa JA. The impact of mean firstyear heart rate on outcomes after heart transplantation: does it make a difference? Clin Transplant. 2013 Aug 8; Epub. 220. Kobashigawa J, Pauly D, Starling R, Eisen H, Ross H, Wang S, Cantin B, Hill J, Lopez, P, Dong G, Nichols S. Cardiac Allograft Vasculopathy by Intravascular Ultrasound in Heart Transplant Patients: Substudy from the Everolimus or Mycophenolate Mofetil Randomized, Multicenter Trial. J Am Coll Cardiol 2013; 1(5):389-399. 221. Azarbal B, Arbit B, Ramaraj R, Kittleson M, Young A, Czer L, Rafiei M, Currier J, Makkar R, Kobashigawa J. Clinical and Angiographic Outcomes with Everolimus Eluting Stents for the Treatment of Cardiac Allograft Vasculopathy. J Interv Cadiol. 2013 Sep 30; Epub. 222. Kobashigawa J, Itagaki B, Razi R, Patel J, Chai W, Kawano M, Goldstein Z, Kittleson M, Fishbein M. Correlation between Myocardial Fibrosis and Restrictive Cardiac Physiology in Patients Undergoing Retransplantation. Clinical Transplantation. 2013 Nov; 27(6):E679-84. 223. Kransdorf E, Czer L, Luthringer D, Patel, J, Montgomery S, Velleca A, Mirocha J, Zakowski P, Zabner R, Gaultier C, Qvarnstrom Y, Benedict T, Steurer F, Bosserman E, Paddock C, Rafiei M, Kobashigawa J. Heart Transplantation for Chagas Cardiomyopathy in the United States. Am J Transplant. 2013 Dec; 13(12):3262-8. 224. White M, Cantin B, Haddad H, Kobashigawa J, Ross H, Carrier M, Pflugfelder P, Isaac D, Cecere R, Whittom L, Ali I, Wang SH, He Y, Groulx A, Touyz R. Cardiac signaling Molecules and Plasma Biomarkers Following Cardiac Transplantation: Impact of Tacrolimus vs. Cyclosporine. J Heart Lung Transplant. 2013 Dec; 32(12):1222-32. 225. Tang Z, Kobashigawa J, Rafiei M, Stern LK, Hamilton M. The Natural History of Biopsy-Negative Rejection after Heart Transplantation. Journal of Transplantation. 2013. Vol. 2013, Article ID 236720. 226. Kansara P, Czer L, Awad M, Arabia F, Mirocha J, De Robertis M, Moriguchi J, Ramzy D, Kass RM, Esmailian F, Trento A, Kobashigawa J. Heart Transplantation With and Without Prior Sternotomy: Analysis of the United Network for Organ Sharing Database. Transplantation Proceedings. 2014 Jan; 46(1): 249-255. 227. Murray K, Wong S, Kittleson M, Ardehali A, Laks H, Shemin R, Kobashigawa J. Selecting Oversized Donor Cardiac Allografts for Patients with Pulmonary Hypertension May Be Unnecessary. Transplantation Proceedings. 2014 Jun; 46(5): 1497-1501 228. Kransdorf E, Kittleson M, Kobashigawa J. Atypical hemolytic-uremic syndrome immediately after heart transplantation. J Heart Lung Transplant. 2014 Jun; 33(6): 664-5. 229. Kittleson M, Kobashigawa J. Management of the ACC/AHA Stage D Patient: Cardiac Transplantation. Cardiol Clin. 2014 Feb;32(1):95 47 CURRICULUM VITAE JON KOB ASHIGAWA, MD 230. Kittleson M, Kobashigawa J. Terasaki Festschrift Report: Statins in Heart Transplantation. Clinical Transplants. 2014 Jul. 231. Kransdorf E, Zakowski P, Kobashigawa J. Chagas Disease in Solid Organ and Heart Transplantation. Curr Opin Infectious Disease. 2014 Oct; 27(5): 418-24. 232. Kittleson M, Kobashigawa J. Long-term care of the heart transplant recipient. Transplant. 2014, 19:515-524. 233. Kwon M, Wong S, Kittleson M, Ardehali A, Laks H, Shemin J, Kobashigawa J. Selecting Oversized Donor Cardiac Allografts for Patients With Pulmonary Hypertension May Be Unnecessary. Transplantation Proceedings. 2014; 46(5): 1497-1501 234. Lee MS, Zimmer R, Kobashigawa J. Long-term Outcomes of Orthotopic Heart Transplantation for Hypertrophic Cardiomyopathy. Transplantation Proceedings. 2014; 46(5):1502-1505. 235. Kobashigawa J. Editorial: Time for Change in US Donor Heart Allocation Policy. J Am Coll Cardiol. 2014;2(2):178-179 236. Kobashigawa J. Editorial: Coronary Computed Tomography Angiography: Is it time to replace the conventional coronary angiogram in heart transplant patients? J Am Coll Cardiol. 2014;63(19):2005-2006 237. Cohen B, Rafiei M, Osborne A, Kobashigawa J. Characteristics of Primary Graft Dysfunction: A Single Center Experience. J Exp Clin Cardiol. 2014; 20(1): 2890-2896 238. Kobashigawa J, Zuckermann A. Everolimus in Heart Transplantation: Does It Finally Have a Home? Am J Transplant. 2014;14(8):1719-1720 239. Rafiei M, Kittleson M, Patel J, Osborne A, Chang D, Czer L, Reinsmoen N, Esmailian F, Kobashigawa J. Anti-thymocyte Gammaglobulin May Prevent Antibody Production after Heart Transplantation. Transplant Proc. 2014;(10):3570-4 240. Kransdorf E, Kittleson M, Kobashigawa J: Atypical hemolytic-uremic syndrome immediately after heart transplantation. J Heart Lung Transplant; 2014 Jun;33(6):664-5 241. Colvin-Adams M, Peura J, Chang P, Fedson S, Francis G, Hsu D, Kiernan M, Kobashigawa J, Lindenfeld J, Masri SC, Miller D, O’Connell J, Rodriguez R, Rosengard B, Self S, Williams CW, Zeevi A. Antibody-Mediated Rejection in Cardiac Transplantation: Emerging Knowledge in Diagnosis and Management. Circulation, Circulation. 2015 May; 131 (18): 1608-39 242. Patel J, Klapper E, Shafi H, Kobashigawa J. Extracorporeal photopheresis in heart transplant rejection. Trans Sci. 2015, Apr; 52(2): 167-170 243. Awad M, Czer L, Mirocha J, Ruzza A, Rafiei M, Reich H, De Robertis M, Rihbany K, Pinzas J, Ramzy D, Arabia F, Trento A, Kobashigawa J, Esmailian F. Prior Sternotomy Increases the Mortality and Morbidity of Adult Heart Transplantation. Transplant Proc. 2015 Mar; 47(2): 485-97 244. Awad M, Czer L, Soliman C, Mirocha J, Ruzza A, Pinzas J, Rihbany K, Chang D, Moriguchi J, Ramzy D, Esmailian F, Kobashigawa J, Arabia F. High Prevalence of Warfarin Genotype Polymorphisms in Patients with Mechanical Circulatory Support. J Heart Lung Transplant. 2015. Jul-Aug; 61(4): 391-6. 245. Ardehali A, Esmailian F, Deng M, Soltesz E, Hsich E, Naka Y, Mancini D, Camacho M, Zucker M, Leprince P, Padera R, Kobashigawa J. A Prospective, Randomized, Multi-center Trial of ex-vivo Donor Heart Perfusion for Human Heart Transplantation: The PROCEED II Trial. Lancet.. 2015 Jun; 385(9987):2577-84 48 Curr Opin Organ CURRICULUM VITAE JON KOB ASHIGAWA, MD P U B L I C A T I O N S : J O U R NA L S – I N P R E S S 1. Kransdorf E, Chang D, Ro R, Reznik R, Yu R, Gordon O, Patel J, Kittleson M, Kobashigawa J. Sympathetic Paraganglioma- Induced Cardiomyopathy Requiring Heart Transplantation. J Heart Lung Transplant. (Pending Publication). 2. Li F, Wei J, Valenzuela N, Lai C, Zhang Q, Gjertson D, Fishbein M, Kobashigawa J, Deng M, Reed E. Phosphorylated S6 Kinase and S6 Ribosomal Protein are Biomarkers of Antibody Mediated Rejection in Heart Allografts. J Heart Lung Transplant. (Pending Publication) 3. Kobashigawa J. Cardiac transplantation in the modern era. N Engl J Med. 2014 (Pending Publication) 4. Kittleson MM, Kobashigawa JA. Management of the Highly Sensitized Patient Awaiting Heart Transplant. http://www.acc.org. January 8, 2015. http://www.acc.org/latest-incardiology/articles/2014/12/22/17/07/management-of-the-highly-sensitized-patient-awaiting-heart-transplantexpert-analysis. 5. Esmailian F, Kittleson M, Kobashigawa J. Human Immunodeficiency Virus in Orthotopic Heart Transplant Case Report. Texas Heart Institute Journal. (In Press) P U B L I C A T I O N S : B O O K C H A P T E R S / M ON O G R A P H S 1. Kobashigawa JA, Stevenson LW. Noninvasive Detection of Acute Cardiac Allograft Rejection. In: Kapoor AS, Laks H, Schroeder JS, Jacoub MH, eds. Cardiomyopathies and Heart-Lung Transplantation. New York: McGraw-Hill, 1991:293-303. 2. Kobashigawa JA, Stevenson LW. Endomyocardial Biopsy. In: Kulich DL, Rahimtoola SH, eds. Techniques and Applications in Interventional Cardiology. St. Louis, Mo: Mosby Year Book, 1991:489-99. 3. Martin SM, Laks H, Drinkwater DC, Stevenson LW, Kawata N, Kobashigawa JA, Moriguchi JD, Hamilton MA. Cardiac Transplantation: The UCLA Experience 1984 to 1990. In: Terasaki P, ed. Clinical Transplantation 1990. Los Angeles, CA: The Regents of the University of California, 1991:103-114 4. Ardehali A, Laks H, Drinkwater DC, Ziv ET, Sorensen TJ, Hamilton MA, Stevenson LW, Moriguchi JD, Kobashigawa JA. Cardiac Transplantation at UCLA. In: Terasaki P, Cecka JM, eds. Clinical Transplants 1993. Los Angeles, CA: The Regents of the University of California, 1994:119-128. 4. Kobashigawa JA. Cardiac Allograft Rejection. In: Kapoor AS, Laks H eds. Atlas of Heart-Lung Transplantation. New York: McGraw-Hill, 1994:95-102. 5. Kobashigawa JA, Kasiske B, Katznelson S, Miller LW, Weisner R. Interdisciplinary perspectives on solid organ transplantation: Focus on hyperlipidemia. Medical Education (monograph), Continuing Medical Education, UCLA School of Medicine, August 1996. 6. Kobashigawa JA, Laks H, Drinkwater DC, Moriguchi JD, Hamilton MA, Hage A, Blitz A, Kawata N. The University of California at Los Angeles Experience in Heart Transplantation. In: Terasaki P, Cecka JM, eds. Clinical Transplants 1995. Los Angeles, CA: The Regents of the University of California, 1996. 7. Kobashigawa JA. Modifications in immunosuppression. In: Cooper DKC, Miller LW, Patterson GA eds. The Transplantation and Replacement of Thoracic Organs. United Kingdom: Kluwer Academic Publishers, 1996. 8. Kobashigawa JA. Pathophysiology of the transplanted heart and its influence on exercise tolerance. In: Balady GJ, Pina IL (eds.) Exercise and Heart Failure. Armonk, NY: Futura Publishing Company, Inc., 1997. 49 CURRICULUM VITAE JON KOB ASHIGAWA, MD 9. Katznelson S, Kobashigawa JA. The effects of HMG-CoA reductase inhibitors after kidney and heart transplantation: lipid lowering and immunosuppression. In: Touraine JL, ed. Late Graft Loss. 1997 Kluwer Academic Publishers, Great Britain. 10. Nonoyama M, Laks H, Drinkwater DC, Brauner R, Ruzevich S, Kobashigawa JA. The UCLA experience with assist devices as a bridge to transplantation in end-stage heart failure. In Akutsu T., Koyanagi H. eds. Heart replacement- Artificial Heart 6. 1998, Springer-Verlag, Tokyo. 11. Kobashigawa JA. Advances in immunosuppression for heart transplantation. In: Advances in Cardiac Surgery, Volume 10. St. Louis, MO: Mosby, Inc. 1998. 12. Kobashigawa JA, Laks H, Marelli D, Moriguchi JD, Hamilton MA, Fonarow G, Hage A, Kawata N. The University of California at Los Angeles Experience in Heart Transplantation. In: Terasaki P, Cecka JM, eds. Clinical Transplants 1998. Los Angeles, CA: The Regents of the University of California, 1998. 13. Kobashigawa JA. Dyslipidemias in heart transplant recipients. American Heart Association Monograph. In: Costanzo MR ed. Longitudinal follow-up and treatment of heart transplant recipients 1999, in press. 14. Kobashigawa JA. Cardiac Complications of Urologic Surgery. In: SS Taneja, RB Smith, RM Ehrlich, eds. Complications of Urologic Surgery: Prevention and Management, Third Edition. Saunders, Inc., 2000. 15. Daniel Marelli, Hillel Laks, Jessica Bresson, Emily Houston, Daniel Fazio, Feng-Chun Tsai, Michele Hamilton, Jaime Moriguchi, Gregg C. Fonarow, Abbas Ardehali, Rocky Camara, Caron Burch, Juan C. Alejos, Barbara George, Nobuyuki Kawata, and Jon Kobashigawa. Chapter 26: Sixteen-Year Experience with 1,000 Heart Transplants at UCLA. Clinical Transplants 2000. Los Angeles, CA: UCLA Immunogenetics Center, Los Angeles, California. 16. Kobashigawa JA. Physiology of the Transplanted Heart. AST Primer on Transplantation, Second Edition, 2001. 17. Kobashigawa JA. Lipids and Lipid Lowering Therapy. Transplant-Associated Coronary Artery Vasculopathy, Eurekah, 2001: 181-188. 18. Patel JK and Kobashigawa JA. Chapter 57: Allograft Coronary Artery Disease. Advanced Therapy in Cardiac Surgery (Second Edition). 2003. 19. Kobashigawa JA. Special Supplement. CNIs in Heart Transplantation: Minimizing the Cardiovascular Risk. Guest editor’s Introduction. J Heart Lung Transplant 2004 May; 23(5 Suppl):S185-6. 20. Kobashigawa JA, Laks H, Wu G, Patel J, Moriguchi J, Hamilton M, Fonarow G, Fishbein M, Ardehali A. The University of California at Los Angeles heart transplantation experience. Clin Transpl. 2005;17385. 21. Patel JK, Kobashigawa JA, Hamilton M. Cardiac, Lipid, and Atherosclerotic Complications Among Lung and Heart-Lung Recipients. Lynch III JP and Ross DJ, eds. Lung and Heart-Lung Transplantation. New York, NY: Taylor & Francis Group, 2006: 881-894. 22. Kobashigawa JA. Congenital Heart Disease in Adults, 3rd Edition. Edited by Dr. Jospeh Perloff. 23. Kobashigawa JA. Transplant in Congenital Heart Disease Patients. Congenital Heart Disease in Adults Book 2006. 24. Kobashigawa JA. Lipids Book Chapter. 2006 25. Patel JK, Kobashigawa JA. Cardiac Allograft Vasculopathy. Book Chapter. Chronic Allograft Failure: Natural History, Pathogenesis, Diagnosis and Management. 2007. 26. Kobashigawa JA. Chapter 40: Hyperlipidemia in Heart Transplantation. Clinical Lipidology: A companion to Braunwald’s Heart Disease. Edited by Dr. Ballantyne. 2008: 490-493. 50 CURRICULUM VITAE JON KOB ASHIGAWA, MD 27. Patel JK, Everly MJ, Kittleson M, Kobashigawa JA. Chapter 25C: Use of Bortezomib as Adjunctive Therapy for Desensitization in Combined Heart and Kidney Transplantation – A Case Report. Clinical Transplants. 2009;347-349. 28. Kobashigawa JA. ISHLT President 2003-2004. 2009. 29. Kobashigawa JA. ISHLT in the 1990’s Decade. 2009. 30. Kittleson M, Kobashigawa JA. Chapter 64: Heart Transplantation. Baliga-McGraw-Hill Specialty Board Review: Cardiology. 2010. 31. Patel JK, Kobashigawa JA. Thoracic Organ Transplantation: Laboratory Methods. Book Chapter. Methods in Molecular Biology: Transplantation Immunology. 2012. 32. Holdaas H, Kobashigawa JA, Fellstrom B, Jardine A. Chapter 40: Special Patient Populations: Transplant Recipients. Clinical Lipidology: A companion to Braunwald’s Heart Disease. 2013 P U B L I C A T I O N S : A BS T R A CT S 1. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. Randomized trial of oral cyclosporine for the treatment of mild acute cardiac rejection. Abstract presented at the Scientific Session of the International Society of Heart Transplantation in April 1988. 2. Moriguchi JD, Stevenson LW, Kobashigawa JA, Westlake C, Laks H, Child J. Decrease in 2-dimensional echocardiographic ejection fraction during transplant rejection: A study of 400 biopsies. (Abstract) J Am Coll Cardiol:121A,1988 3. Krivokapich J, Kobashigawa JA, Stevenson LW. Positron Emission Tomography Reveals Decreased Coronary Flow Response to Exercise after Cardiac Transplantation. Presented at the American College of Cardiology Scientific Session in March 1989. 4. Kobashigawa JA, Murphy F, Stevenson LW, et al. Low dose lovastatin safely lowers cholesterol in cardiac transplant patients. Abstract presented at the American Heart Association Scientific Session in November 1989. 5. Stevenson LW, Moriguchi JD, Kobashigawa JA, Tillisch J, Walden J, Drinkwater DC, Laks H. Decreasing Survival Benefit of Cardiac Transplantation as Waiting List Lengthens. (Abstract) Circulation 1989:80(4);11-671. 6. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. Is an Intravenous Glucocorticoid Pulse Better than Oral Taper for Asymptomatic Cardiac Rejection? A Randomized Trial. Abstract presented at the American College of Cardiology Scientific Session in March 1990. 7. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. Influenza Vaccine Does Not Cause Rejection After Cardiac Transplantation. Abstract presented at the American College of Cardiology Scientific Session in March 1990. 8. Holt C, Fandrich R, Kobashigawa JA, et al. Nursing Strategy to Allow Early Discharge after Cardiac Transplantation: Is it Safe? Abstract presented at the International Society for Heart Transplantation Scientific Session in April 1990. 9. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. A randomized trial of short course OKT3 induction vs. initial triple therapy: Impact on rejection and renal function after cardiac transplantation. (Abstract) J Heart Transplant, 1991;10:163. 10. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. Lack of appropriate erythropoietin response in anemia after cardiac transplantation. (Abstract) J Heart Lung Transplant, 1991;10:178. 51 CURRICULUM VITAE JON KOB ASHIGAWA, MD 11. Chan S, Kobashigawa JA, Stevenson LW, et al. Changes in basal and maximal blood flow during acute cardiac transplant rejection: A non-invasive quantitative study with positron emission tomography. (Abstract) J Heart Lung Transplant 1991;10:174. 12. Kobashigawa JA, Stevenson LW Brownfield E, et al. Outcome of ABO compatible versus identical blood type matching in cardiac transplant recipients on triple immunotherapy. (Abstract) J Am Coll Cardiol 1991;17:309A. 13. Kobashigawa JA, Stevenson LW, Moriguchi JD, et al. Inadequate erythropoietin production in cardiac transplant patients with anemia. (Abstract) J Am Coll Cardiol 1991;17:364A. 14. Kobashigawa JA, Stevenson LW, Louie H, et al. Elevated serum tumor necrosis factor is not useful for monitoring cardiac transplant rejection. Abstract presented at the American College of Cardiology Scientific Session in March 1991. 15. Chelimsky C, Kobashigawa JA, Stevenson LW, et al. Chronic amiodarone therapy poor to cardiac transplantation does not increase the perioperative risk. (Abstract) J Am Coll Cardiol 1991;17:290A. 16. Chan S, Kobashigawa JA, Stevenson LW, et al. Basal myocardial blood flow is increased but maximal flow is decreased during acute cardiac transplant rejection: A non-invasive study. (Abstract) J Am Coll Cardiol 1991:17:58A. 17. Stevenson LW, Warner SL, Hamilton MA, Kobashigawa JA. Distribution of donor hearts to maximize transplant candidate survival. Circulation 1991;84(suppl 11);11-352. 18. Kobashigawa JA, Brownfield E, Shaked A, Busuttil R. Review of Cardiac Complications in 300 liver transplant recipients. (Abstract) Transplantation 1992. 19. Kobashigawa JA, Brownfield E, Shaked A, Busuttil R. Risk factors for cardiac complications following liver transplantation. (Abstract) Transplantation 1992. 20. Brownfield E, Kobashigawa JA, Stevenson LW, et al. B blood type cardiac transplant patients have increased immune related mortality. (Abstract) Transplantation 1992. 21. Brownfield E, Kobashigawa JA, Stevenson LW, et al. Does hemodynamic compromise during cardiac rejection require listing for urgent retransplantation? (Abstract) Transplantation 1992. 22. Brownfield E, Kobashigawa JA, Stevenson LW, et al. Cholesterol lowering with lovastatin after one year does not appear to decrease the risk of transplant coronary artery disease in cardiac transplant recipients. (Abstract) Transplantation 1992. 23. Kobashigawa JA, Naftel D, Bourge R, Kirklin JK, Ventura H, and the Transplant Cardiologists' Research Database Group. Acute rejection after cardiac transplantation: A Multi-Institutional analysis. (Abstract) J Heart Lung Transplant l992;11:192. 24. Kobashigawa JA, Stevenson LW, Albanese E, et al. Initial results of RS-61443 for refractory moderate cardiac rejection. (Abstract) J Heart Lung Transplant 1992;11:200. 25. Stevenson LW, Warner S, Kobashigawa JA, Drinkwater DC, Laks H. All donor hearts will soon be required for urgent candidates. (Abstract) J Heart Lung Transplant 1992;11:191. 26. Kobashigawa JA, Stevenson LW, Brownfield E, et al. Success of steroid weaning late after cardiac transplantation: Relation to HLA-DR Matching. (Abstract) J Am Coll Cardiol 1992;19:204A. 27. Kobashigawa JA, Renlund D, Olsen S, et al. Initial results of RS-61443 for refractory cardiac rejection. (Abstract) J Am Coll Cardiol 1992;19:203A. 28. Brownfield E, Kobashigawa JA, Stevenson LW. B-Antigen confers higher risk of immune related mortality after cardiac transplantation. (Abstract) Clinical Research 1992;40:19A. 29. Brownfield E, Kobashigawa JA, Stevenson LW. Partial matching at HLA DR locus improves late cardiac graft acceptance despite frequent early rejection. (Abstract) Clinical Research 1992;40:33A. 52 CURRICULUM VITAE JON KOB ASHIGAWA, MD 30. Fyfe A, Brownfield E, Kobashigawa JA, Drinkwater DC, Laks H. Rh Incompatible cardiac transplantation is associated with increased early rejection and transplant atherosclerosis. (Abstract) Circulation, November 1992. 31. Fyfe A, Brownfield E, Kobashigawa JA, Stevenson LW. Blood group B endothelia and serum induce high affinity binding of cardiac transplant recipient monocytes. (Abstract) Circulation, November 1992. 32. Fonarow GC, Chelimsky-Fallick C, Hamilton MA, Moriguchi JD, Kobashigawa JA, Walden JA, Tillisch JH, Stevenson LW. Medical therapy has improved to rival cardiac transplantation for advanced heart failure (Abstract) Circulation, November 1992. 33. Kobashigawa JA, Brownfield ED, Stevenson LW, Gleeson MP, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Minkley R, Salamandra J, Ruzevich. Effects of pravastatin in cardiac transplant recipients. (Abstract) J Am Coll Cardiol 1993;21:141A. 34. Kobashigawa JA, Gleeson MP, Stevenson LW, Moriguchi JD, Kawata N, Hage AS, Hamilton MA, Drinkwater DC, Laks H. Significance of mild rejection late after cardiac transplant in patients with and without steroid maintenance. (Abstract) J Am Coll Cardiol 1993;21:36A. 35. Kobashigawa JA, Brownfield ED, Stevenson LW, Moriguchi JD, Hamilton MA, Hage AS, Kawata N, Minkley R, Salamandra J, Ruzevich S, Drinkwater DC, Laks H. Hypercholesterolemia in the first year post cardiac transplant is related to transplant coronary arteriopathy despite subsequent lowering. (Abstract) J Am Coll Cardiol 1993;21:169A. 36. FyfeA, Mojibi N, Kobashigawa JA, Demer LL, Drinkwater DC, Laks H, Stevenson LW. Antibodies to vascular smooth muscle and endothelium after cardiac transplantation. (Abstract) J Am Coll Cardiol 1993;21:334A. 37. Kobashigawa JA, Ogura K, Stevenson LW, Ardehali A, Gleeson MD, Drinkwater DC, Laks H, Terasaki PI. The use of flow cytometry to detect cardiac transplant recipients at risk for early humoral rejection. (Abstract) Transplantation 1993, in press. 38. Fyfe A, Elsayegh A, Kobashigawa JA, Lusis AJ. Anti-chlamydia antibodies after cardiac transplantation are associated with transplant coronary disease. (Abstract) Circulation 1993. 39. Kobashigawa JA, Gleeson MP, Stevenson LW, Brownfield ED, Moriguchi JD, Kawata N, Hage AS, Hamilton MA, Drinkwater DC, Laks H. Benefit of steroid weaning late after cardiac transplant: Relationship to transplant coronary artery disease. J Am Coll Cardiol, February, 1994:230A. 40. Kobashigawa JA, Leaf DA, Gleeson MP, Hamilton MA, Chelimsky-Fallick C, Moriguchi JD, Kawata N, Skotzko C, Herlihy E, Lee N, Stevenson LW. A randomized study of cardiac rehabilitation in heart transplant recipients. J Am Coll Cardiol, February, 1994:356A. 41. Gleeson MP, Kobashigawa JA, Stevenson LW, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Drinkwater DC, Laks H. The natural history of focal moderate rejection in orthotopic heart transplant recipients. J Am Coll Cardiol, February, 1994:483A. 42. Kobashigawa JA, Gleeson MP, Stevenson LW, Carr JG, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Drinkwater DC, Laks H. Prevention of severe cardiac allograft rejection with pravastatin: a randomized trial. J Am Coll Cardiol 1994:483A. 43. Carr JG, Johnson JA, Kobashigawa JA, Sack JB, Yeatman LA. Does the vasodilator response to nitroglycerin over time affect quantitative assessment of coronary artery lesion dimensions using intravascular ultrasound? J Am Coll Cardiol 1994:243A. 44. Kobashigawa JA, Gleeson MP, Stevenson LW. Late steroid weaning in cardiac transplant patients is not associated with an increase in transplant coronary artery disease. J Heart Lung Transplant 1994:13;S48. 53 CURRICULUM VITAE JON KOB ASHIGAWA, MD 45. Kobashigawa JA, Leaf D, Gleeson MP. Benefit of cardiac rehabilitation in heart transplant patients. J Heart Lung Transplant 1994:13;S77. 46. Kobashigawa JA, Gleeson MP, Stevenson LW. Pravastatin lowers cholesterol and may prevent severe cardiac transplant rejection. J Heart Lung Transplant 1994:13;S75. 47. Ruzevich SA, Gleeson MP, Kobashigawa JA, et al. Early hospital discharge despite pre-operative status following cardiac transplant surgery. J Heart Lung Transplant 1994:13;S44. 48. Kobashigawa JA, Gleeson MP, Hamilton MA, Moriguchi JD, Kawata N, Hage AS, Drinkwater DC, Laks H. Survivors of cardiac transplant rejection with hemodynamic compromise appears to be at increased risk to develop transplant coronary artery disease. American Society of Transplant Physicians Scientific Sessions, May 16, 1994 in Chicago, IL. 49. Kobashigawa JA, Gleeson MP, Hamilton MA, Moriguchi JD, Kawata N, Hage AS, Drinkwater DC, Laks H. When to consider cardiac retransplantation in patients who develop transplant coronary artery disease. American Society of Transplant Physicians Scientific Sessions, May 16, 1994 in Chicago, IL. 50. Katznelson S, Kobashigawa JA, Terasaki P, et al. Natural killer cell cytotoxicity is inhibited by pravastatin in heart transplant patients. American Society of Transplant Physicians Scientific Sessions, May 17, 1994 in Chicago, IL. 51. Ardehali A, Laks H, Drinkwater DC, Kobashigawa JA, Moriguchi JD, Drake TA. Vascular cell adhesion molecule-I upregulation precedes and predicts cellular rejection of human cardiac allografts. American College of Surgeons, October 12, 1994 in Chicago, IL. 52. Kobashigawa JA, Carr JG, Moriguchi JD, et al. Pravastatin lowers cholesterol and appears to decrease transplant coronary artery disease: a randomized trial. Circulation 1994;90:1-94. 53. Katznelson S, Kobashigawa JA, Wang XM et al. Pravastatin use in heart transplant patients suppresses natural killer cell (NKC) cytotoxicity and may be associated with reduced allograft rejection. Circulation 1994;90:1-200. 54. Yeung AC, Miller L, Kobashigawa JA, et al. Does induction therapy influence the degree of intimal thickening early after heart transplantation? Circulation 1994;90:1-638. 55. Bourge RC, Naftel DC, Kirklin JK, Spears J, Kobashigawa JA, Young JB, Jarcho J, Kubo S, Smart F. Computerization of the application of parametric multi-variable risk factor analysis to estimate the risk of events after cardiac transplantation. J Am Coll Cardiol February 1995:328A. 56. Laks H, Drinkwater DC, Kobashigawa JA, Gleeson MP. Outcome of patients transplanted with bypassed donor hearts. J Am Coll Cardiol February 1995:142A. 57. Kobashigawa JA, Gleeson MP, Laks H, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Drinkwater DC. Long term outcome of mono-immunosuppression in cardiac transplant recipients. J Am Coll Cardiol February 1995:242A. 58. Laks H, Drinkwater DC, Kobashigawa JA. Long term outcome in cardiac transplant patients transplanted with older donor hearts. J Heart Lung Transplant 1995;14:S41. 59. Johnson M, Naftel D, Hobbs R, Kobashigawa JA, Pitts D, Levine T, Tolman D, Bhat G, Kirklin J, Bourge R. The incremental risk of female gender in cardiac transplantation: a multi-institutional study of pregnancy and peripartum cardiomyopathy. J Heart Lung Transplant 1995;14:S41. 60. Johnson JA, Trosian KD, Yeatman LA, Carr JG, Kobashigawa JA. Morphometric analysis of intracoronary ultrasound: A new method to quantitate transplant coronary disease. J Heart Lung Transplant 1995;14:S49. 61. Ruzevich SA, Sabad A, Kobashigawa JA. Pre-transplant cardiac cachexia does not cause increase in post transplant morbidity or mortality. J Heart Lung Transplant 1995;14:S74. 54 CURRICULUM VITAE JON KOB ASHIGAWA, MD 62. Sabad A, Kobashigawa JA, Minkley R. Is pre-operative obesity a relative contraindication to heart transplantation?: The controversy revisited. J Heart Lung Transplant 1995;14:S74. 63. Kobashigawa JA, Johnson J, Trosian K. Cellular rejection does not appear to be associated with intimal thickening after one year post cardiac transplant: A longitudinal intravascular ultrasound study using qualitative morphometric analysis. American Society of Transplant Physicians, May 1995:106. 64. Katznelson S, Wilkinson AH, Danovitch GM, Wang XM, Chia D, Ozawa, Hirata M, Zhong HP, Kobashigawa JA, Terasaki PI. The impact of pravastatin on the incidence of acute rejection after renal transplantation and on cellular immune function. American Society of Transplant Physicians, May 1995:115. 65. Kobashigawa JA, Sabad A, Cogert GA, Kawata N, Moriguchi JD, Hamilton MA, Hage AS, Drinkwater DC, Laks H. Mild-moderate obesity after cardiac transplant is not associated with transplant coronary artery disease or poor outcome. American Society of Transplant Physicians, May 1995:142. 66. Kofoed KF, Czemin J, Kobashigawa JA, Johnson J, Phelps ME, Schelbert HR. Transplant vasculopathy by intravascular ultrasound is correlated with abnormal microcirculation and vasomotion by PET. Circulation 1995;92:1-244. 67. Westlake CA, Walden JA, Minkley R, Fonarow GC, Hamilton MA, Shpiner RB, Levine MS, Sabad A, Cogert GA, Kobashigawa JA. Smoking and abnormal pulmonary function tests: Are they risk factors for poor outcome after cardiac transplantation? The controversy revisited. Circulation 1995;92:1-178. 68. Miller L, Kobashigawa JA, Hauptman P, Valantine H, Ventura H, O'Donnell J, Yeung A, Wiedermann J, Greenwalt T. Definition of critical cyclosporine level for preventing rejection in heart transplant patients. J Heart and Lung Transplant 1996;15:S77. 69. Laks H, Drinkwater DC, Kobashigawa JA. Alternate heart transplant waiting list: Does it work? J Heart Lung Transplant l996;15:S41. 70. Johnson JA, Kobashigawa JA, Yeatman LA, Carr JG, Trosian KD, Sabad A, Wener LS, Drinkwater DC, Laks H. Does preexisting donor heart atherosclerosis lead to more transplant coronary artery disease? A prospective study using morphometric analysis of intracoronary ultrasound. J Am Coll Cardiol March 1996. 71. Johnson JA, Kobashigawa JA, Yeatman LA, Carr JG, Trosian KD, Sabad A, Wener LS, Drinkwater DC, Laks H. The distribution and characteristics of transplant coronary disease in a prospective morphometric analysis of intracoronary ultrasound. J Am Coll Cardiol March 1996. 72. Salamandra J, Kobashigawa JA, Mansukhani P, Medkiff K, Ruzevich S, Minkley R, Chait J, Utley C, Wagner A, Sabad A, Cogert GA, Drinkwater DC, Laks H. The impact on survival of managed care transplant patients under the care of transplant specialists. American Society of Transplant Physicians, May 1996. 73. Wong CK, Schwarzkopf, Kobashigawa JA, Miller L, Valantine H, Ventura H, Ganz P, Yeung AC. Role of vascular remodeling in the pathogenesis of early transplant coronary artery disease: A multicenter prospective intravascular ultrasound study. Circulation 1996;94(8):I-290. 74. Kobashigawa JA, Moriguchi JD, Laks H, Hamilton MA, Hage AS, Kawata N, Sabad A, Cogert GA, Muhlmeister HF, Drinkwater DC. Successful therapy for cardiac transplant recipients with hemodynamic compromising rejection. Circulation 1996;94(8):I-479. 75. Kobashigawa JA, Sabad A, Cogert GA, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Drinkwater DC, Laks H. Panel reactive antibodies: Are they truly a marker for poor outcome after cardiac transplantation? Circulation 1996;94(9):II:294-297. 76. Kobashigawa JA, Laks H, Fonarow GC, Hamilton MA, Moriguchi JD, Hage AS, Kawata N, Drinkwater DC, Sabad A, Cogert GA, Muhlmeister HF, Schiller GJ. Circulation 1996:94(8):I-479. 55 CURRICULUM VITAE JON KOB ASHIGAWA, MD 77. Czernin J, Johnson JA, Kofoed K, Wener LS, Stepanian C, Laks H, Schelbert HR, Phelps ME, Kobashigawa JA. Quantitative blood flow imaging with PET for predicting progression of transplant vasculopathy. Circulation 1996;94(8):I-649. 78. Kobashigawa JA, Cogert GA, Sabad A, Muhlmeister H, Cassem JD, Moriguchi JD, Kawata N, Hamilton MA, Hage AS, Drinkwater DC, Laks H. Naturally occurring leukopenia as a marker for good outcome after cardiac transplantation. J Am Coll Cardiol 1997;29(2A):28A. 79. Kobashigawa JA, Johnson J, Moriguchi JD, Sabad A, Wener LS, Cogert GA, Hage AS, Hamilton MA, Kawata N, Drinkwater DC, Laks H. Obesity as a risk factor for transplant coronary artery disease: The IVUS truth. J Am Coll Cardiol 1997;29(2A):291A. 80. Kubo S, Stevenson L, Miller L, Kobashigawa JA, Kenzora J, Torre G, Tolman D, Naftel D, Bourge R, Kirklin J. Outcomes in non-urgent patients (status II) awaiting transplantation: Risk factors for death or deterioration to status I (urgent status). J Heart and Lung Transplant 1997,16:42. 81. Czemin J, Johnson J, Sabad A, Schelbert H, Kobashigawa JA. Quantitative blood flow imaging with PET for predicting progression of transplant vasculopathy. J Heart and Lung Transplant 1997,16:67. 82. Kobashigawa JA, Czemin J, Laks H, Sabad A, Cogert GA, Cassem JD, Schelbert H. Pravastatin preserves coronary endothelial-dependent vasodilation determined by positron emission tomography in cardiac transplant patients. J Heart and Lung Transplant 1997.16:47. 83. Johnson JA, Kobashigawa JA, Wener LS, Stepanian C, Sabad A, Cogert GA, Yeatman L, Drinkwater D, Laks H. Histologic validation of morphometric analysis of intravascular ultrasound in quantitative coronary artery disease. J Heart and Lung Transplant 1997,16:48. 84. Kobashigawa JA, Moriguchi JD, Sabad A, Albanese E, Cogert GA, Hamilton MA, Hage A, Kawata N, Cassem JD, Liu H, Drinkwater D, Laks H. Cyclosporine and pravastatin pharmacokinetics in cardiac transplant recipients. J Heart and Lung Transplant 1997;16:84. 85. Moriguchi JD, Kobashigawa JA, Sabad A, Hamilton MA, Hage A, Kawata N, Cogert GA, Cassem JD, Muhlmeister H, Drinkwater D, Laks H. Estrogen therapy in postmenopausal heart transplant women may be effective in cholesterol lowering. J Heart and Lung Transplant 1997,16:84. 86. Katznelson S, Kobashigawa JA, Wang XM Chia D, Ozawa M, Zhong HP, Terasaki PI The inhibitory effects of pravastatin on cytotoxic T-lymphocyte and natural killer cell activity. J Heart and Lung Transplant 1997,16:108 87. Kobashigawa JA, Moriguchi JD, Russell SD, Einhorn K, Ro TK, Inglish JA, Cassem JD, Kawata N, Laks H. Early results of FK506 versus Neoral: a randomized trial. The International Congress on Immunosuppression, Orlando, FL, December 13, 1997. 88. Takemoto S, Johnson C, Terasaki PI, Cecka M, Inglish JA, Cassem JD, Einhorn K, Kobashigawa JA. Flow cytometry panel reactive antibody: a possible tool to detect rejection after cardiac transplant. Circulation 1997,96(8):I-369. 89. Wener LS, Moriguchi JD, Kawata N, Hage A, Hamilton MA, Einhorn K, Inglish JA, Cassem JD, Kobashigawa JA. Redo heart transplant patients are at risk for first year increased intimal thickening by coronary ultrasound. Circulation 1997,96(8):I-369. 90. Guanuggen C, Sen L, Ma XY, Laks H, Kobashigawa JA. Atrial conduction disturbance as an indicator of rejection after cardiac transplantation. Circulation 1997,96(8):I-428. 91. Wong CK, Ganz P, Kobashigawa JA, Miller LW, Valantine-von Kaeppler HA, Ventura HO, Yeung AC. Donor coronary disease serves as a nidus for intimal thickening and prevent adequate remodeling during the first year after transplant: a multicenter transplant intravascular ultrasound study. Circulation 1997,96(8):I-429. 56 CURRICULUM VITAE JON KOB ASHIGAWA, MD 92. Wener LS, Johnson JA, Tobis JM, Einhorn K, Inglish JA, Cassem JD, Curier JW, Kobashigawa JA. Longitudinal study of vascular remodeling in coronary arteries after heart transplantation. Circulation 1997,96(8): I-429. 93. Takemoto SK, Johnson C, Kobashigawa JA, Cecka JM, Gjertson DW, Terasaki PI. Detection of HLA antibody to diagnose cardiac allograft rejection. XVII International Congress of the Transplantation Society Abstracts 1998: 245. 94. Kobashigawa JA, Moriguchi JD, Ro TK, Einhorn K, Cassem JD, Hamilton MA, Hage A, Kawata N, Laks H. Atorvastatin for refractory hypercholesterolemia in heart transplant patients. J Am Coll Cardiol 1998;31: 157A. 95. Kobashigawa JA, Einhorn K, Ro TK, Cassem JD, Moriguchi JD, Hamilton MA, Hage A, Kawata N, Laks H. The meaning of mild rejection in steroid-free heart transplant recipients. J Am Coll Cardiol 1998;31: 35A. 96. Cui G, Ma XY, Kobashigawa JA, Sen L. Atrial conduction disturbance in the post heart transplantation: atrial fibrillation. J Am Coll Cardiol 1998; 31:471A. 97. Wang XM, Kobashigawa JA, Terasaki PI, Moriguchi JD, Einhorn K, Laks H. Pravastatin reduces natural killer cell cytotoxicity in heart transplant patients on FK506. J Heart Lung Transplant 1998;17: 57. 98. Kobashigawa JA, Einhorn K, Ro TK, Cassem J, Moriguchi JD, Hamilton MA, Hage A, Kawata N, Laks H. Mild rejection in steroid-free heart transplant recipients: Is it of concern? J Heart Lung Transplant 1998;17:84. 99. Kobashigawa JA, Moriguchi JD, Ro TK, Einhorn K, Cassem J, Hamilton MA, Hage A, Kawata N, Laks H. Refractory hypercholesterolemia in heart transplant patients: response to atorvastatin. J Heart Lung Transplant 1998;17:107. 100. Kobashigawa JA, Ro TK, Einhorn K, Moriguchi JD, Hamilton MA, Hage A, Kawata N, Laks H. Increased morbidity in insulin-dependent diabetic patients long-term after heart transplantation. ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 101. Kobashigawa JA, Ro TK, Einhorn K, Cogert GA, Cassem JD, Moriguchi JD, Kawata N, Hamilton MA, Hage A, Laks H. Risk factors for malignancies in heart transplant recipients. ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 102. Kobashigawa JA, Einhorn K, Moriguchi JD, Cassem JD, Ro TK, Hamilton MA, Hage A, Kawata N, Laks H. The meaning of mild rejection during corticosteroid weaning in heart transplant recipients. ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 103. Kobashigawa JA, Fishbein M, Inglish JA, Moriguchi JD, Hamilton MA, Hage A, Kawata N, Laks H. Quilty B lesions on endomyocardial biopsies: are they associated with subsequent histologic rejection in cardiac transplant patients? ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 104. Moriguchi JD, Kobashigawa JA, Ro TK, Einhorn K, Cassem JD, Hamilton MA, Hage A, Kawata N, Laks H. At what creatinine level is angiographic dye safe for coronary angiography in cardiac transplant recipients? ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 105. Kobashigawa JA, Ro TK, Moriguchi JD, Cassem JD, Inglish JA, Einhorn K, Cogert GA, Hamilton MA, Hage A, Kawata N, Laks H. Cholesterol lowering after heart transplantation is associated with a lower incidence of transplant coronary artery disease. ASTP Scientific Sessions, Chicago Sheraton Hotel, May 9-13, 1998. 106. Kobashigawa JA, Ro TK, Einhorn K, Moriguchi JD, Hamilton MA, Hage A, Kawata N, Cassem JD, Laks H. Redo heart transplants have increased incidence of transplant coronary artery disease: impact on long-term survival. J Am Coll Cardiol, 1999. 57 CURRICULUM VITAE JON KOB ASHIGAWA, MD 107. Marelli D, Laks H, Fazio D, Moore S, Moriguchi J, Kobashigawa J. The Use of Donor Hearts with Left Ventricular Hypertrophy. J Heart Lung Transplant 1999. 108. Kobashigawa JA, Moriguchi JD, Laks H, Ro TK, Hamilton MA, Hage A, Wener L, Kawata N. Five-year follow-up of a randomized trial of pravastatin in heart transplant patients. J Heart Lung Transplant 1999. 109. Moriguchi JD, Kobashigawa JA, Ro TK, Hamilton MA, Hage A, Kawata N, Laks H. Pretransplant panel reactive antibodies are associated with increased risk of transplant coronary artery disease (TCAD) in cardiac transplant recipients. J Heart Lung Transplant 1999. 110. Chait J, Kobashigawa JA, Chuang J, Moriguchi J, Kawata N, Laks H. Efficacy and safety of sildenafil citrate (Viagra) in male heart transplant patients. J Heart Lung Transplant 1999. 111. Eisenring EM, Canobbio MN, Chait J, Kobashigawa JA, Alejos JC, Rapkin A, Laks H. Does cardiac transplantation affect gynecologic and reproductive outcomes? J Heart Lung Transplant 1999. 112. Kobashigawa JA, Ro TK, Moriguchi JD, Lee R, Cassem JD, Hamilton MA, Hage A, Kawata N, Laks H. Hemodynamic compromising rejection is associated with increased incidence of transplant coronary artery disease in cardiac transplant recipients. J Heart Lung Transplant 1999. 113. Keogh A, St. Vincent’s Hospital, Sydney, Australia. Steering Committee: Bourge R, Costanzo M, Dureau G, Eisen H, Kobashigawa JA, Mehra M, Mentzer R, Miller L, Renlund D, Smart F, Valantine H, on behalf of the Mycophenolate Mofetil Study Investigators. Three year results of the double-blind randomized multicenter trial of mycophenolate mofetil in heart transplant patients. J Heart Lung Transplant 1999. 114. Wang XM, Zhong HP, Takemoto SK, Chuang J, Kobashigawa JA, Terasaki PI, Cecka JM. Immunologic assessment of risk for rejections after heart transplantation. J Heart Lung Transplant 1999. 115. Takemoto SK, Tambur AR, Roggero AL, Ortegal JW, Mancini M, Costanzo MR, Kobashigawa JA, Cecka JM, Gebel HM. Flow cytometric detection of class I and class II antibodies is a predictor if heart allograft rejection. Sixth Congress of the Asian Society of Transplantation 1999;:74. 116. Kobashigawa JA, Lin P, Moriguchi JD, Ro TK, Cassem JD, Hamilton MA, Hage A, Kawata N. Do Heart Transplant Patients on Corticosteroid –Free Immunosuppression Have Less Rejection? Circulation 1999;100(18):I-525. 117. Kobashigawa JA, Ro TK, Chuang J, Moriguchi JD, Schiller G, Kawata N. The Use of Photopheresis for the Treatment of Chronic Humoral Rejection in Heart Transplant Patients. Circulation 1999;100(18):I-526. 118. Kobashigawa JA, Laks H, UCLA Med Ctr. Los Angeles, CA; Admon D, Hadassah University Hospital, Jerusalem, Israel; Hachida M, Koyanagi H, Heart Inst of Japan, Tokyo, Japan. LongTerm Success of Foreign Nationals Undergoing Heart Transplantation in the United States. Circulation 1999;100(18):I-529. 119. Cui G, Kobashigawa J, Sen L. Increased incidence of atrial flutter associated with the rejection of heart transplantation. J Am Coll Cardiol 2000;35:221A. 120. Kobashigawa JA, Moriguchi JD, Chuang JM, et al. A randomized trial of tacrolimus versus neoral cyclosporine in heart transplant recipients. J Am Coll Cardiol 2000;35:222A. 121. Kobashigawa JA, Devereaux D, Moriguchi JD, et al. Effect of race in outcomes after heart transplantation. J Am Coll Cardiol 2000;35:167A. 122. Kobashigawa JA, Moriguchi JD, Takemoto S, Chuang JM, Wener L, Yeatman L, Ro T, Devereaux D, Kawata N, Laks H. First Year Results of a Randomized Trial of Tacrolimus vs. Neoral Cyclosporine in Heart Transplant Patients. J Heart Lung Transplant 2000. 58 CURRICULUM VITAE JON KOB ASHIGAWA, MD 123. Laks H, Marelli D, Fazio D, Sadeghi A, Ardehali A, Hamilton M, Moriguchi J, Fonarow G, Hage A, Esmailian F, Kawata N, Kobashigawa J. Intermediate Term Results of the Alternate Recipient List for Heart Transplantation. J Heart Lung Transplant 2000. 124. Camara R, Kobashigawa JA, Lackey S, Chuang JM, Moriguchi JD, Kawata N, Laks H. Concern Regarding the Use of Orlistat (Xenical) For the Treatment of Obesity in Cardiac Transplant Recipients. J Heart Lung Transplant 2000. 125. Marelli D, Laks H, Fazio D, Sadeghi A, Ardehali A, Moriguchi J, Houston E, Talamo M, Esmailian F, Hage A, Hamilton M, Fonarow G, Kawata N, Kobashigawa J. The Use of Marginal Donor Hearts. J Heart Lung Transplant 2000. 126. Moriguchi JD, Kobashigawa JA, Takemoto S, Wener L, Tobis J, Lee R, Kumar N, Chuang JM, Kawata N, Laks H. Development of Circulating IgG Class I Antibodies is Associated With Increase in Intimal Thickness by Intravascular Ultrasound (IVUS) After Heart Transplant. J Heart Lung Transplant 2000. 127. Moriguchi JD, Bueno P, Kobashigawa JA, Chuang JM, Lackey S, Camara R, Kawata N, Laks H. A Pilot Study of L-Arginine for Renal Insufficiency in Heart Transplant Recipients. J Heart Lung Transplant 2000. 128. Chuang JM, Kobashigawa JA, Mui M, Lackey S, Camara R, Moriguchi JD, Kawata N, Marks M, Velleca A, Brown M, Laks H. What are the Infectious Risks of Pets Immediately After Heart Transplant? J Heart Lung Transplant 2000. 129. Moriguchi JD, Devereaux D, Kobashigawa JA, Lackey S, Camara R, Velleca A, Marks M, Brown M, Chuang JM, Kawata N, Laks H. Long Term Effects of Medical Insurance on Heart Transplant Recipients. J Heart Lung Transplant 2000. 130. Michaels PJ, Fishbein MC, Azarbal A, Espejo ML, Chen L, Laks H, Kobashigawa J. Rantes Expression and Leukocyte Phenotype Distinguish Acute Cellular Rejection (ACR) From Quilty B Lesions (QB). J Heart Lung Transplant 2000. 131. Kobashigawa J. Deleterious Effects of Systemic Hypertension on the Donor Heart after Heart Transplantation. AST Chicago, Chicago Sheraton Hotel, May 15, 2000. 132. Kubak B, Kobashigawa J, et al. Is Cytomegalovirus (CMV) Prophylaxis with Ganciclovir in Heart Transplant Patients Effective? AST Chicago, Chicago Sheraton Hotel, May 15, 2000. 133. Buljubasic N, Kobashigawa J, et al. Comparison of QID and BID Regimen for Initiation of Cyclosporine Treatment Following Heart Transplantation. AST Chicago, Chicago Sheraton Hotel, May 15, 2000. 134. Marelli D, Laks H, Moriguchi J, Fazio D, Hamilton M, Fonarow G, Hage A, Salehmoghaddam S, Kubak B, Meehan D, Talamo M, Sadeghi A, Esmailian F, Ardehali A, Plunkett M, Kobashigawa J. Single Institution Outcome Analysis of 344 Consecutive Patients Receiving Donor Hearts Preserved Using University of Wisconsin Solution. AST Chicago, Chicago Sheraton Hotel, May 15, 2000. 135. Marelli D, Hamilton MA, Laks H, Fonarow GC, Fazio D, Moriguchi JD, Salehmoghaddam S, Kubak B, Ardehali A, Esmailian F, Hage A, Kobashigawa JA. Heart Transplantation in the Elderly. Scientific Sessions 2000, New Orleans, Louisiana, November 12-15, 2000. Circulation 2000;102:II-490. 136. Marelli D, Laks H, Fazio D, Moriguchi JD, Fonarow GC, Salehmoghaddam S, Kubak B, Alejos JC, Galindo A, Kobashigawa JA. Clinical and Laboratory Studies in Thoracic Organ Transplantation. Scientific Sessions 2000, New Orleans, Louisiana, November 12-15, 2000. Circulation 2000;102:II763. 59 CURRICULUM VITAE JON KOB ASHIGAWA, MD 137. Rose ML, Danskine A, Smith JD, Keogh AM, Dureau G, Kobashigawa JA, Dunn MJ, Mycophenolate Mofetil (MMF) Depresses Antibody Production after Cardiac Transplantation. Scientific Sessions 2000, New Orleans, Louisiana, November 12-15, 2000. Circulation 2000;102:II-. 138. Tran TD, Han S, Saab S, Hage A, Kobashigawa J, Lassman C, Martin P. Outcome After Orthotopic Heart Transplantation of Patients with Underlying Liver Disease. International Transplantation Society, Scientific Session 2000, Rome, Italy, August 2000. 139. Rose M, Smith J, Dureau G, Keogh A, Kobashigawa J. Mycophenolate Mofetil (MMF) Decreases Antibody Production After Cardiac Transplantation. International Transplantation Society, Scientific Session 2000, Rome, Italy, August 2000. 140. Boles J, Fonarow G, Kobashigawa J, Hamilton M, Laks H, Feliciano Z. The Role of Implantable Cardioverter-Defibrillators in Advanced Graft Failure Patients Awaiting Orthotopic Heart Transplantation. J Am Coll Cardiol 2001; 37:108A. 141. Cui G, Kobashigawa J, Sen L. Etiology of Atrioventricular Conduction Block in Patient Following Heart Transplantation. J Am Coll Caridiol 2001; 37:189A. 142. Gass A, Eisen H, Griffith B, Kobashigawa J, Koerner M, Mancini D, Mehra M, Meiser B, Webber S. Immunosuppression Induction, Maintenance and Rejection Regimens in 213 Consecutive Transplant Recipients. J Heart Lung Transplant 2001; 20: 121. 143. Tsai F, Marelli D, Laks H, Bresson J, Houston E, Friend L, Kobashigawa J, Lackey S, Camara R. Outcome of Hepatitis C Positive Donors in Cardiac Transplant Recipients in Triple Drug Immunosuppression (TDI). J Heart Lung Transplant 2001; 20: 177. 144. Giesler G, Espejo M, Kubak B, Moriguchi J, Patel J, Laks H, Kobashigawa J. Increased Risk of CMV Infection in Heart Transplant Patient on Mycophenolate Mofetil. J Heart Lung Transplant 2001; 20: 178. 145. Shivkumar K, Espejo M, Kobashigawa J, Watanabe M, Ikeda M, Chuang J, Patel J, Moriguchi J, Hamilton M, Kawata N, Laks H. Sudden Death After Heart Transplantation: The Major Mode of Death. J Heart Lung Transplant 2001; 20: 180. 146. Radovancevic B, McGiffin DC, Kobashigawa JA, Cintron GB, Mullen GM, Pitts DE, O’Donnell J, Thomas C, Bourge RC, Naftel DC. A Multi-Institutional Study of Cardiac Retransplantation: Incidence, Risk Factors for Mortality, and Outcome. J Heart Lung Transplant 2001; 20: 181. 147. Tsai F, Marelli D, Laks H, Houston E, Sykes A, Bresson J, Friend L, Vellaca A, Burch C, Kobashigawa J. Cardiac Allografts with Ischemic Time Over 300 Minutes. J Heart Lung Transplant 2001; 20: 182. 148. Blakey JD, Kobashigawa J, Laks H, Espejo ML, Fishbein M. Sudden, Unexpected Death in Cardiac Transplant Recipients: An Autopsy Study. J Heart Lung Transplant 2001; 20: 229. 149. Gajjar NA, Kobashigawa J, Laks H, Fishbein M. FK506 vs. Cyclosporin: Pathologic Findings in 1067 Endomyocardial Biopsies. J Heart Lung Transplant 2001; 20: 229. 150. Espejo M, Kobashigawa J, Moriguchi J, Patel J, Kumar N, Hamilton M, Hage A, Kawata N, Laks H. The Dilemma of Disability After Heart Transplantation. J Heart Lung Transplant 2001; 20: 244. 151. Marelli D, Tsai F, Laks H, Houston E, Bresson J, Friend L, Gjertson D, Sykes A, Ardehali A, Esmailian F, Hamilton M, Fonarow G, Moriguchi J, Plunkett M, Hage A, Brown M, Mark M, Kobashigawa J. Use of Heart Transplanted from Donors with Atraumatic Intracranial Bleeds. J Heart Lung Transplant 2001; 20: 256. 152. Gass A, Eisen H, Griffith B, Kobashigawa J, Koerner M, Mancini D, Mehra M, Meiser B, Webber S, Young J, Gilb E, Tuteja S. Current practices: immunosuppression induction, maintenance and rejection regimens in 213 consecutive transplant recipients. J Heart Lung Transplant. 2001 Feb;20(2):162 60 CURRICULUM VITAE JON KOB ASHIGAWA, MD 153. Cogert G, Kobashigawa J, Espejo M, Patel J, Moriguchi J, Laks H. Plasmapheresis Lowers the Incidence of Transplant Coronary Artery Disease following Hemodynamic Transplant Rejection. AST Chicago, Chicago Sheraton Hotel, May 15, 2001. 154. Incidence of Biopsy-Proven Cardiac Transplant Rejection Through the 90’s Decade. The 2nd International Congress on Immunosuppression. San Diego, CA. Dec. 6, 2001. 155. The Growing Threat of Malignancies Under Various Heart Transplant Immunosuppressive Regimens From a Single Institution. The 2nd International Congress on Immunosuppression. San Diego, CA. Dec. 6, 2001. 156. Espejo ML, Subherwal S, Hamilton M, Go S, Almeda P, Kobashigawa JA. Is donor heart rejection truly a risk factor for the development of transplant coronary artery disease after heart transplantation [abstract]. J Investig Med 2002;50(1):39A. 157. Subherwal S, Espejo ML, Hamilton M, Kobashigawa JA. The decreasing incidence of cardiac allograft rejection and its impact on clinical trials [abstract]. J Investig Med 2002;50(1):39A. 158. Is donor heart rejection truly a risk factor for the development of transplant coronary artery disease after heart transplantation? American Transplant Congress. Washington, D.C. April 29, 2002. 159. Takemoto S, Gjertson D, Cecka J, Espejo M, Kobashigawa J, Fishbein M, Reed E. Association between post-transplant HLA antibody and histopathologic diagnosis of humoral rejection. ASHI Meeting - Hum. Immunol. 2002 Oct;63(10 Suppl):S84 160. Evangelista L, Dracup K, Doering, Kobashigawa J. Health Risks and Quality of Life of Female Heart Transplant Recipients. American Heart Association Scientific Sessions 2002. Chicago, IL. Nov. 17-20, 2002. 161. Gerard I, Doering L, Evangelista L, Dracup K, Kobashigawa J. What Factors Contribute to Emotional Distress in Women after Heart Transplant? American Heart Association Scientific Sessions 2002. Chicago, IL. Nov. 17-20, 2002. 162. Reyes C, Evangelista L, Doering L, Dracup K, Kobashigawa J. What Predicts Fatigue in Women after Heart Transplant? American Heart Association Scientific Sessions 2002. Chicago, IL. Nov. 17-20, 2002. 163. Cogert GA, Shivkumar K, Hamilton M, Espejo-Vassilakis M, Almeda NP, Kobashigawa JA. The use of implantable cardioverter defibrillators in heart transplant patients at risk for sudden death [abstract]. J Investig Med 2003;51(1):S115. 164. Subherwal S, Cogert GA, Hamilton M, Wu G, Patel JK, Espejo Vassilakis M, Fishbein MC, Kobashigawa JA. Incidence of non-cellular (humoral) rejection unchanged in the 1990 decade despite a decrease in cellular rejection [abstract]. J Investig Med 2003;51(1):S115-6. 165. Go SE, Lee P, Almeda NP, Subherwal S, Cogert G, Cole B, Vassilakis ME, Wang E, Hamilton M, and Kobashigawa JA. The effects of immunosenescence on biopsy proven rejection in older heart transplant recipients [abstract]. J Investig Med 2003;51(1):S116. 166. Wheat J, Odim J, Laks H, Osugi A, Mukherjee K, Alikhani A, Saleh S, Kobashigawa J. Preoperative renal function and outcomes following orthotopic heart transplantation [abstract]. J Investig Med 2003;51(1):S170-171. 167. Zaia B, Gleason BS, Laks H, Mulder D, Kobashigawa JA, Alikhani A, Odim J. Outcomes of heart transplantation using refurbished allografts [abstract]. J Investig Med 2003;51(1):S171. 168. Patel JP, Espejo Vassilakis M, Cole B, Kessler L, Kubak B, Kobashigawa JA, Patel JK. Outcomes Following Cardiac Transplantation in Patients Receiving Allografts from Hepatitis C Positive Donors – The UCLA Experience. Presented at American College of Cardiology Scientific Session, Chicago, IL, Apr 2003. 61 CURRICULUM VITAE JON KOB ASHIGAWA, MD 169. Cruz D, Espejo Vassilakis M, Garfinkel A, Moriguchi J, Fonarow G, Fishbein M, Kobashigawa J, Patel J. The vagrancy of B-type natriuretic peptide (BNP) levels in orthotopic heart transplant (OHT) recipients. Presented at American College of Cardiology Scientific Session, Chicago, IL, April 2003. 170. Odim J, Gleason C, Zaia B, Mulder D, Kobashigawa J, Alikhani A, Laks H. Outcome of heart transplantation using refurbished allografts [abstract]. J Heart Lung Transplant 2003;22(1S):S87. 171. Kao J, Fishbein MC, Kobashigawa JA, Patel JK, McLellan RC, Burdick M, Belperio J, Strieter RM. Elevated levels of the CXCR3 chemokine ligand ITAC is associated with the development of severe transplant coronary artery disease in humans [abstract]. J Heart Lung Transplant 2003;22(1S):S97-98. 172. Cogert GA Subherwal S, Wu G, Patel JK, Vassilakis ME, Fishbein MC, Moriguchi J, Laks H, and Kobashigawa JA. Incidence of non-cellular (humoral) rejection unchanged in the 1990 decade despite a decrease in cellular rejection [abstract]. J Heart Lung Transplant 2003;22(1S):S119-120. 173. Bellg AJ, Grady KL, Naftel DC, Rybarczyk B, Young J, Pelegrin D, Patton-Schroeder K, Kobashigawa J, Chait J, Kirklin J, White-Williams C, Heroux A, Piccione Jr W. Patient adherence at 5 to 6 years after heart transplantation [abstract]. J Heart Lung Transplant 2003;22(1S):S127. 174. Gerard I, Doering LV, Evangelista L, Dracup K, Kobashigawa J. What contributes to emotional distress in female heart transplant recipients? [abstract]. J Heart Lung Transplant 2003;22(1S):S131S132. 175. Baird BL, Velleca AW Erickson VS, Woo MA, Patel JK, Hamilton MA, Kobashigawa JA, and Dracup KA. Rapid assessment of quality of life in patients with advanced heart failure [abstract]. J Heart Lung Transplant 2003;22(1S):S132. 176. Espejo Vassilakis M, Kobashigawa JA, Subherwal S, Fishbein MC, Patel JK, Moriguchi J, Go S, Almeda P and Laks H. Scoring of 2.788 endomyocardial biopsies correlate rejection to the development of transplant coronary artery disease after heart transplantation [abstract]. J Heart Lung Transplant 2003;22(1S):S139. 177. Takemoto SK, Gelbard A, Yuan GW, Vassilakis ME, Michaels PJ, Gjertson DW, Fishbein MC, Reed EF, Kobashigawa JA. Impact of post-transplant antibody in a re-examination of humoral rejection diagnosis [abstract]. J Heart Lung Transplant 2003;22(1S):S170-S171. 178. Odim JNK, Wheat J, Osugi A, Mukherjee K, Alikhani A, Salehi-Rad R, Kobashigawa J, Laks H. Pre-operative renal function and outcomes following orthotopic heart transplantation [abstract]. J Heart Lung Transplant 2003;22(1S):S176. 179. Cogert GA, Shivkumar K, Patel JK, Weiner I, Moriguchi J, Espejo Vassilakis M, Laks H, and Kobashigawa JA. Implantable cardioverter defibrillators in heart transplant patients at risk for sudden death: shocking news? [abstract]. J Heart Lung Transplant 2003;22(1S):S178-179. 180. Grady, KL, Naftel DC, White-Williams C, Belig AJ, Young J, Pelegrin D, Patton-Schroeder K, Kobashigawa J, Chait J, Kirklin J, Piccione Jr W, McLeod M, Heroux A. Predictors of quality of life at 5 to 6 years after heart transplantation [abstract]. J Heart Lung Transplant 2003;22(1S):S220. 181. Evangelista LS, Doering LV, Dracup K, Kobashigawa J. Measuring physical activity among female heart transplant recipients [abstract]. J Heart Lung Transplant 2003;22(1S):S220. 182. Cole BT, Kobashigawa JA, Patel JP, Moriguchi J, Espejo Vassilakis M, Go SE, Chait J, Laks H. Perception is deceiving; the real gender specific exercise capacity of heart transplant recipients [abstract]. J Heart Lung Transplant 2003;22(1S):S220-221. 183. Kobashigawa JA, ML Barr, G Bhat, RL Kormos, MR Mehra and RC Starling. Multi-Center Retrospective Analysis of Cardiovascular and Immunologic Risk Factors Affecting Survival of de Novo Cardiac Transplant Recipients. Accepted for presentation at International Society for Heart and Lung Transplantation Annual Meeting, Vienna, Austria, April 2003. 62 CURRICULUM VITAE JON KOB ASHIGAWA, MD 184. Kobashigawa JA, Takano Y, Tobis JM, Cogert, G, Espejo Vassilakis M, Moriguchi J, Laks H. A randomized trial switching from azathioprine to mycophenolate mofetil in cardiac transplant patients with newly diagnosed angiographic transplant coronary artery disease. Accepted for presentation at American Transplant Congress, Washington DC, June 2003. 185. Kobashigawa JA, Starling RC, Mehra MR, Bhat G, Kormos RL, and Barr ML. Impact of ongoing post cardiac transplant risk factors on outcomes: A multi-center study. Accepted for presentation at American Transplant Congress, Washington DC, June 2003. 186. Kobashigawa JA, Cogert GA, Tobis JM, Currier J, Espejo Vassilakis M, Patel JK, Moriguchi JD, Laks H. Improved survival of heart transplant patients with severe transplant coronary artery disease in the era or percutaneous coronary intervention and statin therapy. Accepted for presentation at American Transplant Congress, Washington DC, June 2003. 187. Ji S, Cesario D, Valderrabano M, Cote S, Hardie M, Boyle NG, Shannon KM, Espejo-Vassilakis M, Hamilton MA, Hage A, Moriguchi JD, Patel JK, Kobashigawa JA, Wiener I, Shivkumar K, UCLA Cardiac Arrhythmia Center, Los Angeles, CA. Mechanistic Basis of Supraventricular Arrhythmias Following Orthotopic Cardiac Transplantation. Accepted for presentation at American Heart Association Conference 2003, Orlando, FL, November 9-11, 2003. 188. Cui G, Fonarow G, Kobashigawa JA, Hamilton M, Moriguchi J, Sen L; UCLA Medical Center/UCLA School of Medicine, Los Angeles, CA. Genotype-Phenotype Correlation of RYR2 Gene Mutations in Inherited Idiopathic Dilated Cardiomyopathy. Accepted for presentation at American Heart Association Conference 2003, Orlando, FL, November 9-11, 2003. 189. Deng MC, Columbia University, New York, NY; Mehra MC, Ochsner Clinic, New Orleans, LA; Eisen HJ, Temple University, Philadelphia, PA; Billingham M, Berry G, Stanford University, Stanford, CA; Marboe C, Itescu S, Columbia University, New York, NY; Johnson F, Palo Alto VA Medical Center, Palo Alto, CA; Kobashigawa JA, University of California Los Angeles, Los Angeles, CA; Wohlgemuth JG, Expression Diagnostics, South San Francisco, CA; Quertermous T, Hunt S; Stanford University, Stanford, CA. Cardiac Allograft Monitoring Using a Novel Clinical Algorithm Based on Peripheral Leukocyte Gene Expression Profiling. Accepted for presentation at American Heart Association Conference 2003, Orlando, FL, November 9-11, 2003. 190. Mehra MR, Uber PA, Park MH, Scott RL, Ventura HO, Deng MC, Eisen H, Billingham M, Kobashigawa JA, Zeevi A, Wohlgemuth J, Phillips J, Hunt S. Molecular Pathways of Cardiac Allograft Dysfunction Independent of Acute Cellular Rejection. Accepted for presentation at American Heart Association Conference 2003, Orlando, FL, November 9-11, 2003. 191. Go SE, Almeda NP, Hamilton M, Kobashigawa JA. Success of geriatric heart transplantation [abstract]. J Investig Med 2004;52(1):S168. 192. Almeda NP, G Cogert, P Lee, Go SE, Hamilton M, Kobashigawa JA. Concern of corticosteroid weaning after heart transplantation [abstract]. J Investig Med 2004;52(1):S168-9. 193. Nakashima J, Marquez A, Oeser BT, Hamilton M, Kobashigawa JA. Early development of cardiac allograft vasculopahty has poor outcome after heart transplantation [abstract]. J Investig Med 2004;52(1):S169. 194. Sue E, Marquez A, Kobashigawa E, Hamilton M, Kobashigawa JA. The development of left ventricular hypertrophy: not a marker for poor outcome after heart transplantation [abstract]. J Investig Med 2004;52(1):S169. 195. Marquez A, Sue E, Kobashigawa E, Hamilton M, Kobashigawa JA. The effects of high blood pressure on outcome after heart transplantation [abstract]. J Investig Med 2004;52(1):S169. 196. Kobashigawa JA, Patel JK, Marquez A, Oeser BT, Moriguchi JD, Laks H, University of California, Los Angeles, Los Angeles, CA. The renal benefit of calcinerin inhibitor-free immunosuppression after heart transplantation: Is it safe? [abstract]. J Am Coll Cardiol 2004;43(5 SupplA):193A. 63 CURRICULUM VITAE JON KOB ASHIGAWA, MD 197. Mitropoulos F, Laks H, Neelankavil J, Alejos J, Child JS, Allada V, Drant S, Kobashigawa JA, Odim J, Fishbein M, Plunkett M. Failing Fontan Circulation Necessitating Transplantation: A Clinicopathologic Correlation [abstract]. J Am Coll Cardiol 2004;43(5 SupplA):390A. 198. Mitropoulos F, Laks H, Neelankavil J, Odim J, Alejos J, Kobashigawa JA, Plunkett M. Orthotopic Heart Transplantation in Patients with Fontan Circulation. Accepted for presentation at the Annual Society of Thoracic Surgery Conference 2004, San Antonio, TX, January 2004. 199. Kobashigawa JA, Tobis J, Mentzer RM, Valantine HA, Bourge RC, Smart FW, Miller LW, Gordon RD. Further analysis of the intravascular ultrasound data from the randomized mycophenolate mofetil (MMF) trial in heart transplant recipients [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S42. 200. Kobashigawa JA, Davis SF, Renlund DG, Hummel M, Gerosa G, Brambilla R. Enteric-coated mycophenolate sodium (EC-MPS) vs. mycophenolate mofetil (MMF) in de novo heart transplant patients: 6 month efficacy and safety results [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S44-S45. 201. Eisen H, Kobashigawa J, Starling RC, Cretin N, Jaffe JS, Murphy J. 24-month safety results of a randomized multicenter, double-blind study of everolimus vs. azathioprine in de novo heart transplant recipients [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S45. 202. Kobashigawa JA, Moriguchi JD, Patel J, Shaw J, Oeser BT, and Laks H. Five-year results of a randomized single center study of tacrolimus (TAC) vs. neoral cyclosporine (CYA) [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S46. 203. Kobashigawa JA, Tobis JM, Starling RC, Tuzcu ME, Mehra MR, Yeung A, Valantine H, Smith A, Anzai H, Oeser BT, Abeywickrama K, Murphy J, Cretin N. Multi-center intravascular ultrasound validation study among heart transplant recipients: Outcomes after 5 years [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S51. 204. Tuzcu EM, Kobashigawa JA, Eisen HJ, Starling RC, Crowe T, Abeywickrama K, Jaffe JS. Favorable effect of everolimus on cardiac allograft vasculopathy is maintained through 24 months [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S51. 205. Takemoto SK, Zhang J, Chang E, Shaw J, Ayele PA, Oeser BT, Gjertson DW, Fishbein MC, Reed ER, Kobashigawa JA. Significance of persistent post-transplant antibody after cardiac transplantation [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S60. 206. Kobashigawa JA, Cogert G, Moriguchi JD, Patel JK, Laks H. The highly sensitized patient awaiting heart transplantation: success with combination therapy of plasmapheresis and intravenous gamma globulin [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S61. 207. Takemoto SK, Cogert G, Oeser BT, Ayele PA, Gjertson DW, Fishbein MC, Reed ER, Kobashigawa JA. Outcome after pre-transplant plasmapheresis for sensitized recipients awaiting heart transplantation [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S61. 208. Grady KL, Naftel DC, Kirklin JK, White-Williams C, Kobashigawa J, Chait J, Young JB, Pelegrin D, Patton-Schroeder K, Rybarczyk B, Daily J, Piccione W, Heroux A. Predictors of physical functional disability at 5-6 years after heart transplantation [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S66. 209. Patel JK, Oeser BT, Go S, Rivera BJ, Plesa ML, Moriguchi JD, Kobashigawa JA. Retransplantation – never too old for one? [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S72. 210. Srikanthan P, Hsueh WA, Kobashigawa JA. The use of thiazolidinedione agents in post cardiac transplant diabetic patients [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S90. 211. Cui G, Kobashigawa J, Sen L. Etiology of low voltage of QRS complex after heart transplantation [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S98-S99. 64 CURRICULUM VITAE JON KOB ASHIGAWA, MD 212. Kobashigawa JA, Miller L, Russell S, Ewald G, Zucker M, Goldberg L, Eisen H, Tolzman D, Fitzsimmons WE. A randomized, prospective, multi-center comparison of tacrolimus, mycophenolate mofetil (MMF) and steroids vs. cyclosporine (modified usp) MMF and steroids vs. tacrolimus, sirolimus and steroids in de novo cardiac transplant recipients – 6 month report [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S106. 213. Mehra MR, Kobashigawa J, Hunt S, Eisen HJ, Starling R, Johnson FL, Murali S, Pauly D, Wohlgemuth JG, Morris MS, Woodward R, Deng MC. Molecular testing and prediction of clinical outcome in heart transplantation: a prospective multicenter trial [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S106. 214. Kobashigawa JA, Moriguchi JD, Cogert G, Hage A, Hamilton MA, Vassilakis ME, Marquez A, Yeatman L, Patel J, Laks H. 10-year results of the pravastatin randomized trial in heart transplant recipients [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S115. 215. Starling RC, Kobashigawa J, Eisen H, Jaffe J, Li Y. Risk factors for acute rejection and casculopathy among 634 patients treated with everolimus or azathioprine [abstract]. J Heart Lung Transplant 2004;23(2 Suppl 1):S138-S139. 216. Kobashigawa JA, Patel JK, Cogert G, Almeda NP, Go S, Lee P, Camara R, Velleca A, Laks H. The dark side of corticosteroid weaning after heart transplantation: Is it worth it? Am J Transplant 2004;4(8):174 217. Kobashigawa JA, Tobis JM, Mentzer RM, Valantine HA, Bourge RC, Smart FW, Miller LW, Gordon RD. Further analysis of the intravascular ultrasound data from the randomized mycophenolate mofetil (MMF) trial in heart transplant recipients. Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 218. Kobashigawa JA, Patel JK, Cogert G, Almeda NP, Go S, Lee P, Camara R, Velleca A, Laks H. The dark side of corticosteroid weaning after heart transplantation: Is it worth it? Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 219. Patel JK, Marquez A, Sue E, Kobashigawa E, Laks H, Kobashigawa JA. The development of left ventricular hypertrophy after heart transplantation: Is this a marker for poor outcome. Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 220. Patel JK, Go S, Fonarow G, Oeser BT, Laks H, Kobashigawa JA. Heart transplantation for patients greater than 65 years: Are we expecting too much? Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 221. Patel JK, Nakashima J, Moriguchi JD, Oeser BT, Marquez A, Laks H, Kobashigawa JA. Poor outcome of early development of cardiac allograft vasculopathy after cardiac transplantation. Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 222. Srikanthan P, Hsueh WA, Kobashigawa JA. Novel immunosuppressive effects of thiazolidinedione agents in post cardiac transplant diabetic patients. Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 223. Mitropoulos FA, Laks H, Kermani R, Marelli D, Ardehali A, Plunkett M, Esmailian F, Odim J, Moriguchi J, Hamilton M, Patel J, Kobashigawa J. Use of donor hearts with left ventricular ejection fraction 50% for transplantation. Accepted for presentation at the American Transplant Congress Annual Meeting 2004, Boston, MA, May 15-19, 2004. 224. Kobashigawa JA, David K, Chu A, Morris J, Steffen B, Gordon R. Daclizumab versus no induction therapy, in combination with cyclosporine microemulsion, mycophenolate mofetil, and corticosteroids, is associated with decreased acute rejection in cardiac transplant recipients and no observed increase in mortality. Accepted for presentation at the XX International Congress of The Transplantation Society, Vienna, Austria, September 5-10, 2004. 65 CURRICULUM VITAE JON KOB ASHIGAWA, MD 225. Kobashigawa JA, Morris JA, David KM, Chu AH, Steffen BJ, Gordon RD. Daclizumab versus no inductions therapy, in combinations with cyclosporine microemulsion, mycophenolate mofetil, and corticosteroids, is associated with decreased acute rejection in cardiac transplant recipients and no observed increase in mortality. The American Heart Association, Nov 7-10, 2004. 226. White-Williams C, Grady K, Naftel DC, Kobashigawa J, Chait J, Kirklin JK, Young JB, Pelegrin D, Patton-Schroeder K, Piccione W, M McLeod, Rybarezyk B, Marenda R, Heroux A. Working at five to six years after heart transplantation. Circulation 2004;110(17):III-700. 227. Nakashima JK, Kobashigawa JA, Patel JK, Yamada C, Hamilton M. Patients with refractory hypercholesterolemia have poor outcome after heart transplantation [abstract]. J Investig Med 2005;53(1):S83. 228. Seid A, Kobashigawa JA, Patel JK, Yamada B, Hamilton M. A multidisciplinary network of social support can positively affect outcome in lower socioeconomic patients (medical/Medicaid insurance) after heart transplantation [abstract]. J Investig Med 2005;53(1):S96. 229. Alison-Mayne S, Patel JK, Kobashigawa JA, Laks H, Hamilton M. The use of marginal donor hearts in heart transplant patients [abstract]. J Investig Med 2005;53(1):S96. 230. Almeda NP, Odim J, Laks H, Patel JK, Hamilton M, Kobashigawa JA. Bypassed donor hearts: the long term outcome after heart transplantation [abstract]. J Investig Med 2005;53(1):S121-2. 231. Go SE, Kobashigawa JA, Patel JK, Hamilton M. Asymptomatic humoral rejection diagnosed on endomyocardial biopsy after heart transplant appears to have clinical significance [abstract]. J Investig Med 2005;53(1):S122. 232. Plesa M, Patel JK, Marquez A, Nakashima J, Kobashigawa JA. Ezetimibe for hypercholesterolemia in patients after heart transplant [abstract]. J Investig Med 2005;53(1):S145. 233. Li H, Tanaka K, Chhabra A, Vadnais D, Kobashigawa J, Tobis J. Vascular remodeling patterns one year after cardiac transplantation [abstract]. J Am Coll Cardiol 2005 Feb;45(Suppl 1):150A. 234. Li H, Tanaka K, Hitoshi A, Oeser B, Kobashigawa J, Tobis JM. Influence of donor transmitted atherosclerosis on the development of cardiac allograft vasculopathy [abstract]. J Am Coll Cardiol 2005 Feb;45(Suppl 1):155A-156A. 235. Busuttil AA, Horwich TB, Fonarow GC, Patel J, Kobashigawa JA. Anemica is associated with a significant increase in mortality in the orthotopic heart transplant population [abstract]. J Am Coll Cardiol 2005 Feb;45(Suppl 1):156A. 236. Kobashigawa JA, Patel JK, Marquez A, Oeser BT, Velleca A, Camara R, Laks H. Calcineurin inhibitor-free renal sparing protocol for patients with renal insufficiency after heart transplantation: trouble on the horizon? [abstract]. J Am Coll Cardiol 2005 Feb;45(Suppl 1):157A. 237. Kobashigawa JA, Ro Thomas, Fishbein MC, Patel JK, Oeser BT, Laks H. Biopsy-proven ISHLT grades 1A, 1B, and 2 rejection in heart transplant patients: should we re-classify them into one mild rejection grade? [abstract]. J Am Coll Cardiol 2005 Feb;45(Suppl 1):157A. 238. Kobashigawa JA, Miller LW, Russell SD. A randomized, prospective, multicenter comparison of Tacrolimus, Mycophenolate Mofetil (MMF) and steroids vs. Cyclosporine Microemulsion, MMF and steroids vs. Tacrolimus, Sirolimus and steroids in de novo cardiac transplant recipients – 6 month report. Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 239. Kobashigawa JA, Tobis J, Mentzer RM, Valantine HA, Bourge RC, Mehra MR, Smart FW, Miller LW, and Gordon RD. Further analysis of the intravascular ultrasound data from the randomized Mycophenolate Mofetil (MMF) trial in heart transplant recipients. Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 240. Kobashigawa JA, Keogh AM, Aaronson K, Perrone S, Brambilla R. Enteric-coated mMycophenolate sodium (EC-MPS) in de novo heart transplant patients: 12-month efficacy and 66 CURRICULUM VITAE JON KOB ASHIGAWA, MD safety data. Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 241. Kobashigawa JA, Patel JK, Furukawa H, Marquez A, Oeser BT, Laks H. Five-year results of a randomized single center study of Tacrolimus vs. Microemulsion Cyclosporine in heart transplant patients. Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 242. Almeda NP, Kobashigawa JA, Patel JK, Camara R, Velleca A, and Laks H. Corticosteroid weaning after heart transplantation: A five-year risk assessment. Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 243. Marquez A, Kobashigawa JA, Patel JK, Oeser BT, Velleca A, Camara R, Laks H. Cyclosporine/Tacrolimus-free renal sparing protocol for patients with renal insufficiency after heart transplantation: is it safe? Presented at 3rd International Congress on Immunosuppression, San Diego, CA, Dec 8-11, 2004. 244. Grady KL, Rybarcyzk B Naftel DC, Kirklin JK, White-Williams C, Kobashigawa J, Chait J, Young JB, Pelegrin D, Czerr J, Higgins R, McLeod M, Rissinger J, Heroux A. Predictors of negative affect at 5-6 years after heart transplantation [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S45. 245. Hare JM, Perrone S, Eisen H, McChurry K, Hauptman P, Simonsen S, Crespo M, Arizon J, Kobashigawa J, Jarcho J. Everolimus in de novo cardiac transplant recipients: 48-month (M) follow-up [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S61. 246. Kobashigawa JA, Miller LW, Felker GM, Russel SD, Ewald GA, Zucker M, Goldberg L, Eisen HJ, Rayburn BK, Wagoner LE, Philbin E, Pereira N, Czerska B, Kormos RL, Weston M, Conte J, Hosenpud J, Aaronson K, Hill J, Copeland JG, Czer L, Anderson A, Dec, GW, Torre-Amione G, Yancy CW, Vega JD, Jarcho JA, Mancini D, Bhat G, First, R, Fitzsimmons W, Tolzman D, Salm K, Gao J. 12 month report of a 3 arm multicenter comparison of tacrolimus (tac), mmf or tac/siolimus(srl) and steroids vs cyclosporine microemulsion(cya), mmf, and steroids in de novo cardiac transplant recipients [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S61-2. 247. Starling RC, Deng MC, Kobashigawa JA, Walther D, Wohlgemuth J, Rosenberg S, Mehra MR.. The influence of corticosteroids on the alloimmune molecular signature for cardiac allograft rejection [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S65-6. 248. Patel JK, Ro T, Fishbein MC, Oeser BT, Marquez A, Laks H, Kobashigawa JA. Justification of the newly proposed ISHLT biopsy grading scale by combining grades 1A, 1B, and 2 into one mild rejection grade [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S66. 249. Laks H, Mitropoulos F, Odim J, Patel JK, Marquez A, Plesa M, Oeser BT, Kobashigawa JA. Long-term outcome of alternate list heart transplant patients [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S70. 250. Odim J, Laks H, Almeda NP, Patel JK, Kobashigawa JA. CABG-patched donor hearts: the long term outcome [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S71. 251. Eisen HJ, Mancini D, Vigano M, Kobashigawa J. Evaluation of cyclosporine (CsA) profiles month 2 to 6 in an international phase III randomized, multicenter, double-blind study of everolimus in de novo heart transplant recipients [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S89. 252. Li H, Tanaka K, Anzai H, Oeser B, Kobashigawa J, Tobis JM. Influence of donor transmitted atherosclerosis on the development of cardiac allograft vasculopathy [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S90-1. 253. Lepin EJ, Hong L, Zhang QJ, Gjertson DW, Kobashigawa JA, Fishbein MC, Reed EF. Phosphorylation of S6 ribosomal protein at serine 235/236 is a marker of human heart transplantation [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S97. 67 CURRICULUM VITAE JON KOB ASHIGAWA, MD 254. Kobashigawa JA, Fishbein MC, Patel JK, Oeser BT, Almeda NP, Alison-Mayne S, Seid A, Laks H. Should humoral rejection be included in the new ISHLT biopsy grading scale [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S144. 255. Patel JK, Kobashigawa JA, Marquez A, Oeser BT, Velleca A, Camara R, Laks H. Caution using a calcineurin inhibitor-free renal sparing protocol for heart transplant patients with renal dysfunction [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S160. 256. Kobashigawa JA, Renlund DG, Gerosa G, Caforio A, Ross H, Lehmkuhl HB, Eisen HJ, Segovia J, Brambilla, R. Twelve months results of enteric-coated mycophenoalte sodium (EC-MPS) in de novo heart transplant patients showed excellent efficacy and safety [abstract]. J Heart Lung Transplant 2005 Feb;24(2S):S380. 257. Patel JK, Mitropoulos F, Laks H, Moriguchi JD, Wang EZ, Oeser BT, Kobashigawa JA. Nesiritide immediately after heart transplantation: a pilot study [abstract]. Am J Transplant 2005;5(Suppl 11):169. 258. Odim J, Yao W, Laks H, Saran M, Kobashigawa J, Gjertson D. The influence of adverse donor factors on outcome of pediatric heart transplantation – the marginal donor allograft [abstract]. Am J Transplant 2005;5(Suppl 11):220. 259. Lepin EJ, Jindra PT, Zhang Q, Jin YP, Kobashigawa JA, Fishbein MC, Reed EF. S6 ribosomal protein is a novel biomarker of heart allograft rejection [abstract]. Am J Transplant 2005;5(Suppl 11):238. 260. Kobashigawa JA, Gerosa G, Caforio A, Renlund DG, Ross H, Yonan N, Hummel M, Segovia J, Almenar L, Brambilla R. Enteric Coated mycophenolate sodium (EC-MPS) is comparable to mycophenolate mofetil in de novo heart transplant patients. Twelve month efficacy and safety results [abstract]. Am J Transplant 2005;5(Suppl 11):244. 261. Eisen JH, Mancini D, Vigano M, Kobashigawa J, Preiss M. Cyclosporin (CsA) profiles at months (M) 2 to 6 in a randomized, multicenter, double-blind study of everolimus vs. azathioprine in de novo heart transplant recipients [abstract]. Am J Transplant 2005;5(Suppl 11):244. 262. Kobahisgawa JA, Miller LW, Russell SD, Ewald GA, Zucker M, First R, Fitzsimmons W, Salm K. A randomized, prospective, multicenter comparison of tacrolimus (TAC), mycophenolate mofetil (MMF) and steroids vs cyclosporine microemulsion, MMF and steroids vs TAC, sirolimus and steroids in de novo cardiac transplant recipients 12 month report [abstract]. Am J Transplant 2005;5(Suppl 11):250. 263. Kobashigawa J, Hare J, Eisen H, McCurry K, Hauptman P, Simonsen S, Arizon J, Perrone S, Jarcho J, Moeller V. Everolimus in cardiac transplantation: 48 month results [abstract]. Am J Transplant 2005;5(Suppl 11):251. 264. Eisen H, Starling R, Yang L, Ricci F, Kobashigawa J. 4-year incidence of MACE and economic burden in de novo heart transplant patients: a comparison of everolimus and azathioprine [abstract]. Am J Transplant 2005;5(Suppl 11):251. 265. Odim J, Saran M, Yao W, Kobashigawa J, Laks H. The fate of older cardiac allografts in adolescents [abstract]. Am J Transplant 2005;5(Suppl 11):285. 266. Laks H, Almeda P, Kobashigawa J, Odim J. Twenty-year single institution experience with 1460 heart transplants. Accepted for presentation at the 15th World congress 2005, WSCTS - World Society of Cardio-Thoracic Surgeons, Le Meridien Villon Resort & Convention Centre, Vilnius, Lithuania, Vienna, Austria, June 19-23, 2005. 267. Miller S, Patel JK, Lee P, Wu GW, Chi L, Fishbein M, Laks H, Kobashigawa JA. Hemodynamic Compromise Predicts Future Cardiac Allograft Vasculopathy and Nonfatal Major Ad verse Cardiac Events. J Investig Med 2006;54(1):S120. 68 CURRICULUM VITAE JON KOB ASHIGAWA, MD 268. Mansukhani A, Smooke S, Wu GW, Hamilton MA, Kobashigawa JA. The High Incidence of Glucose Intolerance and New-Onset Diabetes after Cardiac Transplantation is not Affected by Choice of Calcineurin Inhibitor. J Investig Med 2006;54(1):S120. 269. Sarkissian S, Ro T, Patel JK, Wu GW, Hamilton MA, Kobashigawa JA. What is the Outcome of International Society for Heart & Lung Transplantation Grade 1A/1B Rejections under Various Immunosuppressive Regimens? J Investig Med 2006;54(1):S120. 270. Kawano J, Cruz D, Wu GW, Patel JK, Sarkissian S, Vaidya V, Laks H, Kobashigawa JA. Average First-Year Brain Natriuretic Peptide Predicts Poor Outcome after Heart Transplantation. J Investig Med 2006;54(1):S149. 271. Wu GW, Patel JK, Reed E, Gjertson D, Hamilton MA, Kobashigawa JA. Flow CytometryPositive, Cytotoxicity-Negative Donor-Specific Crossmatch: To Transplant or Not to Transplant, That is the Question. J Investig Med 2006;54(1):S150. 272. Seid A, Mansukhani A, Wu GWW, Hamilton MA, Kobashigawa JA. When to List for Redo Heart Transplant in Patients with Severe Cardiac Allograft Vasculopathy. J Investig Med 2006;54(1):S150. 273. Parikh A, Patel JK, Kubak B, Thompson OM, Patel JP, Hamilton MA, Kobashigawa JA. Hepatitis C Donor Hearts in Noninduction Immunosuppressive Regimens Portend Poor Outcome after Heart Transplantation. J Investig Med 2006;54(1):S150. 274. Eisen H, Starling R, Kobashigawa J. 4-year incidence of MACE and economic burden in de novo heart transplant patients: A comparison of everolimus and azathioprine (AZA). J Heart Lung Transplant. 2006; 25(2S):59. 275. Deng MC, Cadeiras M, Baron HM, Marboe HM, Starling RC, Eisen H, Valantine H, Hunt SA, Kobashigawa J, Mehra MR, Pauly DF, Murali S, Mital S, Berry G, Billingham M, Wohlgemuth J, Dedrick R. Early detection of cardiac allograft vasculopathy through gene expression profiling – insights of the CARGO study. J Heart Lung Transplant. 2006; 25(2S):98. 276. Patel JK, Seid A, Mansukhani A, Thompson OM, Wu GW, Laks H, Kobashigawa JA. When To list for re-do heart transplant in patients with severe cardiac allograft vasculopathy. J Heart Lung Transplant. 2006; 25(2S):100-101. 277. Patel JK, Reed E, Gjertson D, Wu GW, Laks H, Kobashigawa JA. Flow-cytometry positive, cytotoxicity-negative donor-specific crossmatch: To transplant or not to transplant, that is the question. J Heart Lung Transplant. 2006; 25(2S):108. 278. Patel JK, Lai C, Fishbein MC, Go SE, Wu GW, Laks H, Kobashigawa JA. Asymptomatic humoral rejection after heart transplantation: Does it require therapy? J Heart Lung Transplant. 2006; 25(2S):109. 279. Mehra MR, Kobashigawa JA, Deng MC, Johnson FL, Baron HM, Uber PA, Lal P, Klingler T, Rosenberg S, Eisen HJ. The clinical role of gene expression testing in anticipating the future development of acute cardiac allograft rejection. J Heart Lung Transplant. 2006; 25(2S):110. 280. Kobashigawa J, Renlund DG, Lehmkuhl HB, Segovia J. Adequate cyclosporine (CsA) microemulsion (Neoral®) C2-levels critical within the first 30 days to prevent rejection after cardiac transplant. J Heart Lung Transplant. 2006; 25(2S):111. 281. Patel JK, Parikh A, Kubak B, Thompson OM, Patel JP, Laks H, Kobashigawa JA. Hepatitis C donor hearts in non-induction immunosuppressive regimens portend poor outcome after heart transplantation. J Heart Lung Transplant. 2006; 25(2S):114. 282. Grady KL, Naftel DC, Kobashigawa J, Chait J, Young JB, Pelegrin D, Czerr J, McLeod M, Heroux A, Higgins R, White-Williams C, Kirklin JK. Patterns and predictors of quality of life at 5– 10 years after heart transplantation. J Heart Lung Transplant. 2006; 25(2S):131. 69 CURRICULUM VITAE JON KOB ASHIGAWA, MD 283. Cruz D, Wu GW, Patel JK, Kawano J, Sarkissian S, Thompson OM, Vaidya V, Laks H, Kobashigawa JA. Average first-year BNP predicts poor outcome after heart transplantation. J Heart Lung Transplant. 2006; 25(2S):132. 284. Ro T, Patel JK, Sarkissian S, Wu GW, Laks H, Kobashigawa JA. What is the outcome of ISHLT grade 1A/1B rejections under various immunosuppressive regimens? J Heart Lung Transplant. 2006; 25(2S):134. 285. Smooke S, Dev S, Patel JK, Kawano J, Almeda NP, Thompson OM, Wu GW, Laks H, Kobashigawa JA. Pre-transplant glucose intolerance and not diabetes predicts non-fatal major adverse cardiac events after cardiac transplantation. J Heart Lung Transplant. 2006; 25(2S):138. 286. Lai CK, Reed EF, Zhang Q, Gjertson D, Cecka M, Kobashigawa JA, Wallace WD, Fishbein MC. HLA Antibodies with C4d Staining and Pathologic Diagnosis of Humoral Rejection. Am J Transplant. 2006; 6(2S):70. 287. Odim O, Gleason C, Kobashigawa JA, Laks H, Gjertson D. The Impact of Gender Matching on Mortality and Rejection after Heart Transplantation. Am J Transplant. 2006; 6(2S):551. 288. Vaidya VS, Cruz D, Wu GW, Patel JK, Sarkissian S, Kawano J, Laks H, Kobashigawa JA. Persistently Elevated B-Type Natriuretic Peptide (BNP) Levels after Acute Allograft Rejection in Heart Transplant Recipients Predict Poor Outcomes. Am J Transplant. 2006; 6(2S):558. 289. Patel JK, Kawano J, Wu GW, Laks H, Kobashigawa JA. Efficacy of Photopheresis for Recurrent/Refractory Humoral and Cellular Rejections in Heart Transplant Patients. Am J Transplant. 2006; 6(2S):146-7. 290. Patel JK, Miller S, Kawano J, Sarkissian S, Seid A, Wu GW, Laks H, Kobashigawa JA. Intravenous Immunoglobulin as Part of Combined Immunotherapy Appears Effective for Late (>30 Days) Complex Rejection after Cardiac Transplantation. Am J Transplant. 2006; 6(2S):147. 291. Zhang Q, Kobashigawa JA, Ge P, Wu G, William WD, Fishbein MC, Reed EF. HLA and MICA: Targets of Antibody Mediated Rejection in Heart Transplantation. Am J Transplant. 2006; 6(2S):244. 292. Patel JK, Reed E, Gjertson G, Wu GW, Laks H, Kobashigawa JA. Flow-Cytometry Positive, Cytotoxicity-Negative Donor-Specific Crossmatch is Associated with Good Outcome Following Cardiac Transplantation Using Non-Induction Immunosuppressive Regimen. Am J Transplant. 2006; 6(2S):775. 293. Patel JK, Lai C, Fishbein MC, Go SE, Wu GW, Laks H, Kobashigawa JA. Asymptomatic Humoral Rejection after Heart Transplantation is Associated with the Development of Cardiac Allograft Vasculopathy. Am J Transplant. 2006; 6(2S):379-80. 294. Lai CK, Reed EF, Kobashigawa JA, Hong L, Chen L, Gan JJ, Fishbein MC. Does C4d Deposition Alone in Cardiac Allografts Predict the Future Occurrence of Antibody-Mediated Rejection? Am J Transplant. 2006; 6(2S):380. 295. Patel JK, Lee P, Miller S, Lai C, Fishbein M, Wu GW, Laks H, Kobashigawa JA. Hemodynamic Compromise Rejection Predicts Future Cardiac Allograft Vasculopathy and Non-Fatal Major Adverse Cardiac Events. Am J Transplant. 2006; 6(2S):381-2. 296. Patel JK, Parikh A, Kubak B, Patel JP, Laks H, Kobashigawa JA. Poor Outcome after Heart Transplantation with Hepatitis C Donor Hearts and Non-Induction Immunosuppressive Regimens. Am J Transplant. 2006; 6(2S):382-3. 297. Deng MC, Cadeiras M, Lim WK, Baron HM, Marboe CB, Starling R, Eisen H, Hunt SA, Kobashigawa J, Mehra MR, Pauli D, Murali S, Wohlgemuth J, Klingler T, Dedrick R, Califano A. Reconstructing the Creb-Network from 285 Leukocyte-Arrays in CARGO Yields Insight into Transcription Factor Function during Quiescence and Rejection. Am J Transplant. 2006; 6(2S):423. 70 CURRICULUM VITAE JON KOB ASHIGAWA, MD 298. Patel JK, Smooke SJ, Kawano J, Almeda NP, Wu GW, Laks H, Kobashigawa JA. The High Incidence of Glucose Intolerance and New-Onset Diabetes after Heart Transplantation is not Affected by Choice of Calcineurin Inhibitor. Am J Transplant. 2006; 6(2S):556. 299. Yajnik M, Vaidya VS, Patel JK, Cruz D, Wu GW, Kittleson MM, Hamilton MA Kobashigawa JA. The Validity of B-Type Natriuretic Peptide Blood Levels to Detect Heart Failure in Heart Transplant Patients. J Investig Med 2007;55(1):S136. 300. Kawano MA, Patel JK, Kittleson MM, Hamilton MA, and Kobashigawa JA. Pharmacologic Myocardial Perfusion Stress Testing to Detect Significant Cardiac Allograft Vasculopathy-Is It Worthwhile? J Investig Med 2007;55(1):S137. 301. Seid A, Aye O, Patel JK, Chinakarn L, Kittleson MM, Hamilton MA, Kobashigawa JA. Increased Infection Risk of Non-Cardiac Surgeries after Heart Transplantation. J Investig Med 2007;55(1):S137. 302. Gokanapudy L, Itagaki BK, Kobashigawa JA, Wu GW, Brubaker W D, Kawano MA, Kittleson MM, Hamilton MA, and Patel JK. Re-Transplantation for Heart Failure with Preserved Systolic Function. J Investig Med 2007;55(1):S137. 303. Brubaker WD, Itagaki BK, Kobashigawa JA, Wu GW, Kawano MA, Kittleson MM, Hamilton MA, and Patel JK. The Stiffer the Heart, the Worse the Outcome after Heart Transplantation. J Investig Med 2007;55(1):S137. 304. Chinakarn L, Kawano MA, Song H, Patel JK, Hamilton MA, and Kobashigawa JA .Outcome of Combined Kidney and Redo Heart Transplant Recipients from a Single Center. J Investig Med 2007;55(1):S137. 305. Itagaki BK, Kobashigawa JA, Wu GW, Patel JK, Kawano MA, Kittleson MM, Hamilton MA, and Fishbein MC. Widespread Fibrosis of Myocardial and Adjacent Tissues Causing Restrictive Cardiac Physiology in Patients Needing Re-do Heart Transplant. J Investig Med 2007;55(1):S137. 306. Song H, Kittleson MM, Yajnik M, Wu GW, Kobashigawa BI, Patel JK, Hamilton MA, and Kobashigawa JA. Naturally Occurring Leukopenia as a Marker for Good Outcome after Cardiac Transplantation. J Investig Med 2007;55(1):S158. 307. Patel JK, Kawano MA, Wu GW, Kawano JC, Yajnik M, Kittleson MM, Kobashigawa JA. Practically Speaking: The initiation of lower dose mycophenolate mofetil (MMF) 1000 mg bid appears to have similar outcome to 1500 mg bid after heart transplantation. J Heart Lung Transplant 2007; 26(2S):S70. 308. Vaidya VA, Yajnik M, Patel JK, Cruz D, Wu GW, Kittleson MM, Kobashigawa JA. The validity of BNP blood levels to detect heart failure in heart transplant patients. J Heart Lung Transplant 2007;26(2S):S120-1. 309. Itagaki BK, Kobashigawa JA, Wu GW, Patel JK, Kawano MA, Kittleson MM, Fishbein MC. Widespread fibrosis of myocardial and adjacent tissues causing restrictive cardiac physiology in patients needing re-do heart transplant. J Heart Lung Transplant 2007;26(2S):S138. 310. Itagaki BK, Kobashigawa JA, Wu GW, Brubaker W, Kawano MA, Gokanapudy L, Kittleson MM, Patel JK. The stiffer the heart, the worse the outcome after heart transplantation. J Heart Lung Transplant 2007;26(2S):S183. 311. Patel JK, Kawano JC, Wu GW, Chinakarn L, Kawano MA, Kobashigawa BI, Kittleson MM, Gordon AL, Kagimoto SM, Kobashigawa JA. Recurrent mild rejection in the first year after heart transplantation does not affect outcomes: validation of the revised ISHLT grading system. J Heart Lung Transplant 2007;26(2S):S226. 312. Zhang Q, Si K, Ge P, Wu GW, Patel JK, Kobashigawa J, Fishbein MC, Reed EF. HLA and MICA: Targets of antibody mediated rejection in heart transplantation. J Heart Lung Transplant 2007;26(2S):S106. 71 CURRICULUM VITAE JON KOB ASHIGAWA, MD 313. Shao ES, Chen TE, Wu GW, Patel JK, Kobashigawa JA. Cardiac transplantation for giant cell myocarditis: A single center experience. J Heart Lung Transplant 2007;26(2S):S154. 314. Kobashigawa JA, Kawano MA, Wu GW, Kawano JC, Yajnik M, Kittleson MM, Patel JK. Firstyear mycophenolate mofetil does reductions: Do they portend poor outcome? J Heart Lung Transplant 2007;26(2S):S228. 315. Aye O, Patel JK, Seid A, Chinakarn L, Kittleson MM, Kobashigawa JA. Increased infection risk of non-cardiac surgeries after heart transplantation. J Heart Lung Transplant 2007;26(2S):S236. 316. Patel JK, Kawano MA, Kittleson MM, Kobashigawa JA. Pharmacological myocardial perfusion stress testing to detect significant cardiac allograft vasculopathy- is it worthwhile? J Heart Lung Transplant 2007;26(2S): S236-7. 317. Miller SJ, Kobashigawa JA, Kittleson MM, Patel JK, Kawano MA, Ardehali A. The use of ECMO/Intra-aortic balloon pump to support hemodynamics in patients with cardiogenic shock due to severe rejection. J Heart Lung Transplant 2007;26(2S):S237. 318. Itagaki BK, Kobashigawa JA, Wu GW, Brubaker W, Kawano MA, Gokanapudy L, Kittleson MM, Patel JK. Re-transplantation for heart failure with preserved systolic function. J Heart Lung Transplant 2007;26(2S):S237-8. 319. Kittleson MM, Song H, Yajnik M, Wu GW, Kobashigawa BI, Patel JK, Kobashigawa JA. Naturally occurring leucopenia as a marker for good outcome after cardiac transplantation. J Heart Lung Transplant 2007;26(2S):S254-5. 320. Bernstein D, Berry G, Billingham M, Marboe CC, Deng MC, Mital S, Eisen H, Williams GE, Baron H, Klinger TM, Wohlgemuth, Kobashigawa J. Gene expression profiling distinguishes moderate to severe from mild acute cellular rejection in cardiac allograft recipients. J Heart Lung Transplant 2007;26(2S):S121. 321. Grady KL, Naftel DC, Young JB, Pelegrin D, Czerr J, Higgins R, Heroux A, McLeod M, Rybarczyk B, Kobashigawa J, Chait J, White-Williams C, Myers S, Kirklin JK. Patterns and predictors of physical functional disability at 5-10 years after heart transplantation. J Heart Lung Transplant 2007;26(2S):S191. 322. Hunt J, Bedanova H, Starling RC, Rabago G, Banner NR, Kobashigawa J, Keogh A, Kormos R, Mehra M, Wahlers T, Noeldeke J. Premature termination of a prospective, open label, randomized, multicenter study of sirolimus to replace calcineurin inhibitors (CNI) in a standard care regimen of CNI, MMF, and corticosteroids early after heart transplantation. J Heart Lung Transplant 2007;26(2S):S203. 323. Patel JK, Kawano MA, Wu GW, Chinakarn L, Song H, Kittleson MM, Kobashigawa JA. Heart Transplantation in Septagenarians: Is It Worth It? Am J Transplant 2007;7(S2):406. 324. Kobashigawa J, Kiyosaki K, Kubak B, Patel J, Kittleson M, Ardehali A. Surgical Treatment of Heart Failure Transplantation and Arrhythmias I. “Successful Use of Immune Monitoring (Cylex) In Heart Transplantation for Rejection and Infection Risk. Scientific Sessions 2007, Orlando, FL, November 4-7, 2007. Circulation Oct 2007;116: II-572. 325. Kobashigawa J, Patel J, Kawano M, Wu G, Kittleson M, Kiyosaki K, Moriguchi J, Ardehali A. Surgical Treatment of Heart Failure Transplantation and Arrhythmias II. “The Long Term Outcome of Treated Presensitized Patients who Undergo Heart Transplantation: Is It Successful?” Scientific Sessions 2007, Orlando FL, November 4-7, 2007. Circulation Oct 2007;116: II-644. 326. A. Vaidya, M. Kawano, M. Hamilton and J. Kobashigawa. Long Term Risks of Steroid Weaning After Heart Transplantation. J Investig Med 2008; 56(1):212. 327. A. Ankrom, M. Hamilton and J. Kobashigawa. The Use of Aliskiren, a New Blood Pressure Medication, in Heart Transplant Patients. J Investig Med 2008; 56(1):213. 72 CURRICULUM VITAE JON KOB ASHIGAWA, MD 328. D. Patel, K. Kiyosaki, M. Kawano, M. Hamilton, and J. Kobashigawa. The Outcome of Lower Social Economic Status After Heart Transplantation. J Investig Med 2008; 56(1):213. 329. A. Brown, J. Kawano, M. Kawano, M. Hamilton, and J. Kobashigawa. Reduction in Malignancy with Use of Newer Immunosuppressive Regimens in Heart Transplant Patients. J Investig Med 2008; 56(1):213. 330. E. Sue, M. Kawano, M. Hamilton, and J. Kobashigawa. The Outcome of Successfully Treated Pre-Transplant Sensitized Patients After Heart Transplantation. J Investig Med 2008; 56(1):214. 331. H. Song, M. Kawano, K. Kiyosaki, D. Patel, M. Hamilton, and J. Kobashigawa. Kidney Transplant Prolongs Survival in Patients with End Stage Kidney Disease After Heart Transplantation. J Investig Med 2008; 56(1):214. 332. M. Kawano, J. Kawano, M. Hamilton, and J. Kobashigawa. Hypercholesterolemia Resistant to Statin Therapy in First Year After Transplant is High Risk for Future Complications. J Investig Med 2008; 56(1):214. 333. S. Carr, K. Kiyosaki, A. Ankrom, M. Kawano, M. Hamilton, and J. Kobashigawa. Adverse Effects of Sirolimus Versus Everolimus After Heart Transplantation. J Investig Med 2008; 56(1):215. 334. M. Yajnik, V. Vaidya, M. Kawano, A. Ankrom, M. Hamilton, and J. Kobashigawa. The Economic Outcome of Heart Transplantation Versus Medical Therapy of Advanced Heart Failure Patients. J Investig Med 2008; 56(1):215. 335. B. Simenhoff, M. Kawano, M. Hamilton, and J. Kobashigawa. Reduced Immune Response in the Older Heart Transplant Patient. J Investig Med 2008; 56(1):215. 336. K. Kiyosaki and J. Kobashigawa. A Simple Blood Test to Assess Risk for Rejection/Infection in Heart Transplant Patients. J Investig Med 2008; 56(1):216. 337. E. Kobashigawa, K. Kiyosaki, U. Duong, M. Hamilton, and J. Kobashigawa. Employment After Heart Transplantation and the Effects of Governmental Health Insurance Policies. J Investig Med 2008; 56(1):256. 338. B. Itagaki, M. Kawano, M. Hamilton and J. Kobashigawa. Coronary Spasm After Heart Transplantation. J Investig Med 2008; 56(1):263. 339. Kobashigawa JA, Reed E, Sue E, Patel JK, Kittleson MM, Kawano MA, Kiyosaki KK, Ardehali A. Successfully Treated Pre-transplant Sensitized Patients Have Favorable Post-Transplant Outcomes. J Heart Lung Transplant 2008;27(2S):S19. 340. Itagaki B, Patel JK, Kittleson MM, Kawano MA, Ardehali A, Kobashigawa JA. The Innocence of Coronary Spasm after Heart Transplantation. J Heart Lung Transplant 2008;27(2S):S23. 341. Patel JK, Simenhoff B, Kittleson MM, Kawano MA, Ardehali A, Kobashigawa JA. Making Sense of Immunosenescence in Older Heart Transplant Recipients. J Heart Lung Transplant 2008;27(2S):S33. 342. Kittleson MM, Song HS, Patel JK, Kawano MA, Patel D, Kiyosaki KK, Ardehali A, Kobashigawa JA. End-stage Renal Disease after Heart Transplantation The Benefits of Kidney Transplantation. J Heart Lung Transplant 2008;27(2S):S23. 343. Patel JK, Kawano JC, Kittleson MM, Duong U, Ardehali A, Kobashigawa JA. First-Year Statin Resistant Hypercholesterolemia: A Cause for Concern in the Development of Cardiac Allograft Vasculopathy. J Heart Lung Transplant 2008;27(2S):S45. 344. Kittleson MM, Carr SA, Patel JK, Kawano MA, Kiyosaki KK, Ankrom AK, Ardehali A, Kobashigawa JA. Everolimus May Have Lower Adverse Effect Profile Compared to Sirolimus in Heart Transplant Patients. J Heart Lung Transplant 2008;27(2S):S30. 73 CURRICULUM VITAE JON KOB ASHIGAWA, MD 345. Patel JK, Brown A, Kittleson MM, Kawano JC, Kawano MA, Kiyosaki KK, Ardehali A, Kobashigawa JA. Malignancy Risk in 2007 with Current Immunosuppression Regimens. J Heart Lung Transplant 2008;27(2S):S23. 346. Kobashigawa JA, Kiyosaki KK, Patel JK, Kittleson MM, Ardehali A. Success of Immune Monitoring with ImmuKnow (Cylex) to Assess Rejection/Infectious Risk in Heart Transplantation. J Heart Lung Transplant 2008;27(2S):S41. 347. Patel JK, Itagaki B, Ankrom A, Kawano MA, Kiyosaki KK, Yajnik M, Abbas A, Kobashigawa JA. Hemodynamic Compromise Rejection: Diagnose and Treat Cardiac Rejection and Vasculopathy Before it is Too Late. J Heart Lung Transplant 2008;27(2S):S41. 348. Kittleson MM, Vaidya AS, Patel JK, Kawano MA, Ardehali A, Kobashigawa JA. Long-Term Risks Post Steroid Weaning: Not so Rosy After All. J Heart Lung Transplant 2008;27(2S):S23. 349. Kittleson MM, Kawano JC, Patel JK, Kawano MA, Yajnik MV, Kiyosaki KK, Ardehali A, Kobashigawa JA. Hypercholesterolemia in Heart Transplant Patients on Proliferation-Signal Inhibitors: Is Statin Therapy Effective? J Heart Lung Transplant 2008;27(2S):S29. 350. Vaidya VS, Yajnik M, Heidenreich P, Kawano MA, Vaidya AS, Patel JK, Kittleson MM, Ankrom AK, Ardehali A, Kobashigawa JA. Comparison of Survival and Costs Between Transplantation and Medical Treatment of End Stage Heart Failure. J Heart Lung Transplant 2008;27(2S):S34. 351. Moriguchi J, Kwon M, Punkett M, Esmailian F, Jocson R, Laks H, Marelli D, Beygui R, Davis S, Ardehali A, Patel J, Kobashigawa J. Improved Clinical Outcomes Using Bi-Ventricular Assist Devices as Bridges to Transplant in Critically Ill Patients. J Heart Lung Transplant 2008;27(2S):S38. 352. Kittleson MM, Ankrom AK, Patel JK, Kawano MA Ardehali A, Kobashigawa JA. Aliskiren: A New Anti-Renin Blood Pressure medication Appears Safe and Effective in Heart Transplant Recipients. J Heart Lung Transplant 2008;27(2S):S23. 353. Grady KL, Wang E, Higgins R, Heroux A, Rybarczyk B, Young JB, Pelegrin D, Czerr J, Kobashigawa J, Chait J, Naftel DC, White-Williams C, Myers S, Kirklin JK. Symptom Frequency and Distress from 5 to 10 years after Heart Transplantation. J Heart Lung Transplant 2008;27(2S):S29. 354. Marelli D, Kobashigawa JA, Hamilton MA, Noguchi E, Moriguchi JD, Patel JK, Laks H, Esmailian F, Beygui R, Plunkett MD, Ardehali A. Long Term Outcome of Heart Transplant in the Elderly. J Heart Lung Transplant 2008;27(2S):S33. 355. Marelli D, Kobashigawa J, Beygui R, Esmailian F, Laks H, Plunkett M, Ardehali A. Tricuspid Valve Regurgitation (TR) after Heart Transplantation Using the Bicaval Anastomosis Technique. J Heart Lung Transplant 2008;27(2S):S36. 356. Marelli D, Kobashigawa JA, Moriguchi JD, Shuvayev I, Wong SY, Kahn T, Patel JK, Beygui R, Esmailian F, Laks H, Plunkett MD, Ardehali A. ECMO to Salvage Severe Cardiogenic Shock in Advanced Heart Failure and Transplantation. J Heart Lung Transplant 2008; 27(2S):S37. 357. Grady KL, Wang E, Young JB, Pelegrin D, Czerr J, Kobashigawa J, Chait J, Heroux A, Higgins R, Rybarczyk B, McLeod M, Naftel DC, Myers S, Kirklin JK. Are Patients Working at 5 to 10 Years after Heart Transplantation? J Heart Lung Transplant 2008;27(2S):S54. 358. Kittleson MM, Patel JK, Kawano, MA Kubak, Ardehali A, Kobashigawa JA. Aggressive Antimicrobial Prophylaxis Decreases Infectious Risk Despite Rejection Therapy after Heart Transplantation. Am J Transpl 2008;8(S2):348. 359. Wei JP, Lu WH, Lai C, Gjertson DW, Zhang Q, Kiyosaki KK, Kobashigawa JA, Fishbein MC, Reed EF. Phosphorylated S5 Kinase and S6 Ribosomal Protein are Biomarkers of Antibody Mediated Rejection in Heart Allografts. Am J Transpl 2008;8(S2):569. 360. Carr S, Hamilton M, Kobashigawa J, Obesity and cardiac allograft vasculopathy after heart transplantation. J Investig Med 2009;57(1):158. 74 CURRICULUM VITAE JON KOB ASHIGAWA, MD 361. Lo K, Hamilton M, Kobashigawa J, The predictive value of cardiopulmonary stress testing after heart transplantation. J Investig Med 2009;57(1):158-159. 362. Kiyosaki K, Hamilton M, Kobashigawa J, A non-invasive means to detect risk for rejection and infection in heart transplant patients in a large cohort of patients. J Investig Med 2009;57(1):159. 363. Moradzadeh N, Hamilton M, Kobashigawa J, Right ventricular dysfunction in heart transplant recipients. J Investig Med 2009;57(1):159. 364. Kawano M, Hamilton M, Kobashigawa J, the outcome of heart transplant patients with positive donor specific crossmatch. J Investig Med 2009;57(1):159-160. 365. Ankrom A, Hamilton M, Kobashigawa J, Cardiac allograft sizing in heart transplant candidates with pulmonary hypertension. J Investig Med 2009;57(1):160. 366. Arbit A, Hamilton M, Kobashigawa J, First year heart rate and outcome after heart transplantation. J Investig Med 2009;57(1):160. 367. Sohrabian S, Hamilton M, Kobashigawa J, The outcome of renal sparing protocols after heart transplantation. J Investig Med 2009;57(1):160. 368. Wong S, Hamilton M, Kobashigawa J, The value of social worker and psychiatric pre-heart transplant evaluation. J Investig Med 2009;57(1):161. 369. Patel J, Hamilton M, Kobashigawa J, Pulmonary function testing pre-heart transplant can predict outcome. J Investig Med 2009;57(1):186. 370. Yajnik M, Hamilton M, Kobashigawa J, Outcome of older redo heart transplant patients. J Investig Med 2009;57(1):186-187. 371. Kim B, Hamilton M, Kobashigawa J, Permanent pacemakers in heart transplant patients. J Investig Med 2009;57(1):240. 372. K Kiyosaki, J Kobashigawa, J Patel, J Patel, A Ankrom, M Kittleson, M Kawano, J Moriguchi, E Shao, A Ardehali. The Benefit of Immune Monitoring (Cylex): A Review of 864 Immune Monitoring Assays in Heart Transplantation. J Heart Lung Transplant 2009. 373. K Kiyosaki, J Kobashigawa, E Reed, J Moriguchi, M Kawano, A Ankrom, J Patel, M Kittleson, E Shao, A Ardehali. The Outcome of Treatment of 100% PRAs in Heart Failure Patients Awaiting Heart Transplantation. J Heart Lung Transplant 2009. 374. K Lo, K Kiyosaki, J Kobashigawa, M Kawano, A Ankrom, M Kittleson, E Shao, J Moriguchi, J Patel, A Ardehali. Low Peak Oxygen Consumption by Cardiopulmonary Stress Testing After Heart Transplantation Predicts Poor Outcome. J Heart Lung Transplant 2009. 375. B Kim, K Kiyosaki, E Shao, J Patel, M Kittleson, M Kawano, A Ankrom, J Moriguchi, A Ardehali, J Kobashigawa. Early Permanent Pacemaker After Heart Transplantation is a Surrogate Marker for Poor Outcome: Possible Immune Mechanisms. J Heart Lung Transplant 2009. 376. J Patel, K Kiyosaki, B Kubak, M Kawano, A Ankrom, M Kittleson, E Shao, J Moriguchi, A Ardehali, J Kobashigawa. Surreptitious Aspergillus Colonization is Not Associated with Poor Outcome While on Suppressive Azole Therapy. J Heart Lung Transplant 2009. 377. E Shao, M Kawano, K Kiyosaki, J Patel, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. Late Rapidly Progressive Cardiac Allograft Vasculopathy is Associated with Poor Outcome. J Heart Lung Transplant 2009. 378. J Patel, M Kawano, K Kiyosaki, A Ankrom, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. When is Too Old, Too Old for Redo Heart Transplantation? J Heart Lung Transplant 2009. 75 CURRICULUM VITAE JON KOB ASHIGAWA, MD 379. S Sohrabian, M Kawano, K Kiyosaki, A Ankrom, J Patel, J Moriguchi, M Kittleson, A Ardehali, J Kobashigawa. Spare Me the Renal Sparing Protocol - Poor Long Term Outcomes. J Heart Lung Transplant 2009. 380. M Kawano, J Kobashigawa, K Kiyosaki, A Ankrom, J Patel, M Kittleson, E Reed, A Ardehali. Outcome of Retrospective Positive Donor Specific Crossmatch After Heart Transplantation - Are They Doomed? J Heart Lung Transplant 2009. 381. J Patel, M Kawano, K Kiyosaki, E Shao, A Ankrom, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. Addressing the Myth of Elevated Bilirubin as a Contraindication to Heart Transplantation. J Heart Lung Transplant 2009. 382. E Moreno, A Velleca, M Kawano, K Kiyosaki, S Wong, A Ankrom, J Patel, M Kittleson, L Ventura, J Moriguchi, A Ardehali, J Kobashigawa. Does High Risk Status Identified by PreTransplant Social Worker and Psychiatric Evaluation Predict Outcome After Heart Transplant? J Heart Lung Transplant 2009. 383. A Ankrom, J Patel, E Shao, S Carr, M Kawano, M Kittleson, K Kiyosaki, J Moriguchi, A Ardehali, J Kobashigawa. Obesity Confers Protection from Cardiac Allograft Vasculopathy. J Heart Lung Transplant 2009. 384. E Shao, M Kawano, N Moradzadeh, A Ankrom, K Kiyosaki, J Patel, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. Right Ventricular Dysfunction Immediately Post Transplant - A Marker for Poor Outcome? J Heart Lung Transplant 2009. 385. E Shao, M Kawano, J Patel, M Kittleson, A Ankrom, K Kiyosaki, J Moriguchi, A Ardehali, J Kobashigawa. The Problem of Rejection in Redo Heart Transplant Recipients. J Heart Lung Transplant 2009. 386. J Patel, E Shao, J Patel, M Kawano, K Kiyosaki, A Ankrom, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. Pre-Transplant FEV1/FVC but not FEV1 alone by Pulmonary Function Testing Predicts Poor Outcome After Heart Transplantation: The Bane of COPD. J Heart Lung Transplant 2009. 387. J Patel, B Kubak, M Kawano, A Ankrom, M Yajnik, K Kiyosaki, M Kittleson, J Moriguchi, A Ardehali, J Kobashigawa. The Efficacy of Shorter Duration CMV Prophylaxis After Heart Transplantation. J Heart Lung Transplant 2009. 388. M Kwon, A Ankrom, A Ardehali, M Kawano, K Kiyosaki, J Kobashigawa. Oversizing Donor Cardiac Allografts for Patients with Pulmonary Hypertension May Not Be Necessary. J Heart Lung Transplant 2009. 389. Sasaoka T, Kato T, Kobashigawa J, Patel J et al. Retrospective Review of Japanese Heart Transplant Recipients Transplanted in Japan and Transplanted at UCLA in the U.S. J Heart Lung Transplant 2009. 390. Zuckerman A, Kobashigawa J, Arizon JM, Wang SS, Vigano M, Lehmkuhl H, Ross H, Dong G, Eisen H. Incidences of Incisional Complications after De Novo Cardiac Transplantation in AZA-, MMF- or Everolimus-Based Regimens: A Cross-Study Analysis on 1008 Patients. J Heart Lung Transplant 2009. 391. White M, Cantin B, Haddad H, Kobashigawa J, Ross H, Carrier M, Whittom L, Ali I, Isaac D, Wang S. Subclinical Inflammation and Oxidative Stress Following De Novo Cardiac Transplantation: Similar Impact of Tacrolimus vs. Cyclosporine Microemulsion. Accepted for presentation at the Canadian Cardiovascular Congress, Edmonton, October 25, 2009. 392. Davis S, Hamilton M, Kobashigawa J, Asymptomatic positive CMV serology is associated with increased risk for the development of cardiac allograft vasculopathy (CAV) after heart transplantation. J Investig Med 2010;58(1):113. 393. Kawano M, Hamilton M, Kobashigawa J, Accommodation after heart transplantation. J Investig Med 2010;58(1):113. 76 CURRICULUM VITAE JON KOB ASHIGAWA, MD 394. Share M, Hamilton M, Kobashigawa J, C4D or C3D positivity in heart transplant biopsies is not a marker for poor outcome. J Investig Med 2010;58(1):113. 395. Moradzadeh A, Hamilton M, Kobashigawa J, Donor to recipient height match in addition to weight match is important for good outcome after heart transplantation. J Investig Med 2010;58(1):115. 396. Goldstein Z, Hamilton M, Kobashigawa J, Safe transition of pediatric heart transplant patients to the adult heart transplant program. J Investig Med 2010;58(1):169. 397. Patel J, Kittleson M, Reed E, Aguas G, Kawano M, Davis S, Burch C, Velleca A, Stimpson E, Moriguchi J, Ardehali A, Kobashigawa J. The Importance of Anti-HLA DQ Antibodies as a Risk Factor for the Development of Transplant Coronary Artery Disease (TCAD) After Heart Transplantation. J Heart Lung Transplant. 2010; 29(2): S73-S74. 398. Kittleson M, Patel J, Reed E, Gjertson D, Kawano M, Davis S, Burch C, Velleca A, Stimpson E, Moriguchi J, Ardehali A, Kobashigawa J. Accommodation after Heart Transplantation: Does it Exist? J Heart Lung Transplant. 2010; 29(2): S63. 399. Lai C, Patel J, Fishbein M, Kittleson M, Share M, Davis S, Kawano M, Moriguchi J, Ardehali A, Kobashigawa J. C4d in Heart Transplant Biopsies Does Not Appear to Represent Poor Outcome. J Heart Lung Transplant. 2010; 29(2): S38. 400. Moreno E, Velleca A, Burch C, Patel J, Kittleson M, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Pre-Transplant Smoking in Heart Transplant Patients: A Marker for Long Term Outcome? J Heart Lung Transplant. 2010; (29)2: S60. 401. Kittleson M, Patel J, Moriguchi J, Kawano M, Patel K, Davis S, Hage A, Hamilton M, Ardehali A, Kobashigawa J. Heart Transplant Rejection with Cardiogenic Shock Supported with Extracorporeal Membrane Oxygenation (ECMO): Outcome from a Single Center Experience. J Heart Lung Transplant. 2010; 29(2): S91. 402. Velleca A, Burch C, Montgomery S, Lockhart D, Patel J, Kittleson M, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. The Threat of Medication Miscommunication in NonEnglish Speaking Heart Transplant Recipients. J Heart Lung Transplant. 2010; 29(2): S125. 403. Kawano M, Kittleson M, Fishbein M, Patel J, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Review of 12,703 Endomyocardial Biopsies: The Truth of Quality Lesions in the Cyclosporine and Tacrolimus Era. J Heart Lung Transplant. 2010; 29(2): S73. 404. Kawano M, Patel J, Kittleson M, Reed E, Gjertson D, Cecka M, Velleca A, Stimpson E, Burch C, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. The Incidence and Outcome of Sensitization in Patients Awaiting Re-do Heart Transplantation. J Heart Lung Transplant. 2010; 29(2): S123-S124. 405. Patel J, Kittleson M, Reed E, Zhang Q, Rajalingam R, Velleca A, Stimpson E, Burch C, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. The Effectiveness of a Standardized Desensitization Protocol in Reducing Calculated Panel Reactive Antibodies (cPRA) in Sensitized Heart Transplant Candidates: Does it Make Sense to Desensitize? J Heart Lung Transplant. 2010; 29(2): S103-S104. 406. Kittleson M, Patel J, Azarbal B, Moriguchi J, Kawano M, Davis S, Hage A, Ardehali A, Kobashigawa J. First Angioplasty Does Not Appear to Alter Outcome in Heart Transplant Patients with Newly Diagnosed Transplant Coronary Artery Disease. J Heart Lung Transplant. 2010; 29(2): S124. 407. Patel J, Kittleson M, Zhang Q, Reed E, Kawano M, Davis S, Cecka M, Burch C, Velleca A, Stimpson E, Moriguchi J, Ardehali A, Kobashigawa J. Are Circulating Antibodies Necessary To Make A Diagnosis Of Antibody-Mediated Rejection? J Heart Lung Transplant. 2010; 29(2): S54. 77 CURRICULUM VITAE JON KOB ASHIGAWA, MD 408. Kittleson M, Patel J, Reed E, Zhang Q, Cecka M, Stimpson E, Velleca A, Burch C, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Does MFI Quantitation Of Circulating Antibodies Correlate With Positive Cytotoxicity? J Heart Lung Transplant. 2010; 29(2): S152. 409. Kittleson M, Patel J, Moriguchi J, Moradzadeh A, Kawano M, Davis S, Ardehali A, Kobashigawa J. The Adverse Effects of Sirolimus in Heart Transplant Patients: Is it Worth it? J Heart Lung Transplant. 2010; 29(2): S22. 410. Patel J, Kittleson M, Share M, Kawano M, Davis S, Fishbein M, Lai C, Moriguchi J, Ardehali A, Kobashigawa J. Persistent Pulmonary Hypertension In Heart Transplant Patients: Is This A Recipe For Long-Term Failure? J Heart Lung Transplant. 2010; 29(2): S92. 411. Patel J, Kittleson M, Kubak B, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Asymptomatic Positive CMV Serology is Associated with Increased Risk for the Development of Transplant Coronary Artery Disease (TCAD): Who Needs Symptoms? J Heart Lung Transplant. 2010; 29(2): S124. 412. Patel J, Kittleson M, Kubak B, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Development Of Cytomegalovirus (CMV) Infection During Ongoing Valganciclovir Therapy. J Heart Lung Transplant. 2010; (29)2: S66-S67. 413. Shemin R, Patel J, Ardehali A, Kittleson M, Kawano M, Davis S, Moriguchi J, Kobashigawa J. Gender Mismatch in Non-induction/Triple-Drug Regimens: Poor 10-Year Outcomes. J Heart Lung Transplant. 2010; 29(2): S102. 414. Montgomery S, Kawano M, Lockhart D, Velleca A, Burch C, Patel J, Davis S, Kittleson M, Moriguchi J, Ardehali A, Kobashigawa J. Does Race Mismatch Have An Impact On Outcome After Heart Transplantation? J Heart Lung Transplant. 2010; 29(2): S124-S125. 415. Patel J, Kittleson M, Azarbal B, Hage A, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Does A Normal Angiogram Further From Heart Transplantation Confer Less Chance To Develop CAV?; Should We Still Do Annual Angiograms Late After Transplantation? J Heart Lung Transplant. 2010; 29(2): S53. 416. Burch C, Amegatcher A, Patel J, Kittleson M, Kawano M, Davis S, Goldstein Z, Moriguchi J, Ardehali A, Kobashigawa J. Transition Of Pediatric Heart Transplant Patients To The Adult Heart Transplant Program: Are They Doomed To Be Rejected? J Heart Lung Transplant. 2010; 29(2): S33. 417. Kittleson M, Moriguchi J, Kwon M, Reed E, Davis S, Kawano M, Burch C, Velleca A, Stimpson E, Patel J, Ardehali A, Kobashigawa J. Highly Sensitized Patients on VAD Support awaiting Heart Transplant on a Ventricular Assist Device (VAD) Appear to have a Less Robust Immune Response Compared to Non-VAD Patients. J Heart Lung Transplant. 2010; 29(2): S120. 418. Lockhart D, Doering L, Burch C, Montgomery S, Velleca A, Patel J, Kittleson M, Davis S, Kawano M, Goldstein Z, Moradzadeh A, Moriguchi J, Ardehali A, Kobashigawa J. Are Recipients From Heart Donors Listed as Homeless at Increased Risk for Poor Outcome After Heart Transplantation? J Heart Lung Transplant. 2010; 29(2): S39. 419. Kwon M, Moriguchi J, Kittleson M, Patel J, Kawano M, Davis S, Reed E, Burch C, Velleca A, Stimpson E, Ardehali A, Kobashigawa J. Lack of Sensitization In Patients Awaiting Heart Transplantation On Heartmate II Axial Flow Assist Devices. J Heart Lung Transplant. 2010; 29(2): S183. 420. Davis S, Patel J, Kittleson M, Kawano M, Moriguchi J, Hamilton M, Ardehali A, Kobashigawa J. Potential Immunomodulatory Effects of Granulocyte Colony Stimulating Factor (GCSF) in Heart Transplant Patients. Am J Transplant. 2010;10(S4):407. 421. Kawano M, Patel J, Kittleson M, Hamilton M, Hage A, Moradzadeh A, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. The Effects of Donor Height in Heart Transplant Patients on Triple Drug Immunosuppression. Am J Transplant. 2010;10(S4):310. 78 CURRICULUM VITAE JON KOB ASHIGAWA, MD 422. Kittleson M, Patel J, Moriguchi J, Moradzadeh A, Kawano M, Davis S, Ardehali A, Kobashigawa J. Splenectomy Prior to Heart Transplantation Does Not Affect Risk for Rejection and/or Infection after Heart Transplantation in Patients on Triple Drug Immunosuppression. Am J Transplant. 2010;10(S4):407. 423. Kittleson M, Patel J, Kawano M, Davis S, Share M, Moriguchi J, Hamilton M, Ardehali A, Kobashigawa J. Safety and Efficacy of Sildenafil in the 1st Year after Heart Transplantation for Pulmonary Hypertension. Am J Transplant. 2010;10(S4):307. 424. Azarbal B, Patel J, Kittleson M, Davis S, Kawano M, Moradzadeh A, Goldstein Z, Moriguchi J, Ardehali A, Kobashigawa J. Treadmill Nuclear Stress Testing Appears Effective to Detect Coronary Ischemia in Heart Transplant Patients with Established Transplant Coronary Artery Disease. Am J Transplant. 2010;10(S4):309. 425. Patel J, Kittleson M, Davis S, Kawano M, Moriguchi J, Ardehali A, Kobashigawa J. 10-Year Follow-up of Hepatitis C Donor Hearts in Triple-Drug Immunosuppression: The Final Nail in the Coffin. Am J Transplant. 2010;10(S4):120. 426. Patel J, Kittleson M, Kawano M, Davis S, Moriguchi J, Ardehali A, Kobashigawa J. Are Quality B Lesions in Heart Transplant Biopsies in Patients on Tacrolimus Immunosuppression Harbingers of Rejection? A Review of 3651 Endomyocardial Biopsies. Am J Transplant. 2010;10(S4):404. 427. Tatishchey S, Czer L, Kobashigawa J, Luthringer D. Utility of CD68/CD31 Dual Immunostaining Techniques to Detect Antibody-Mediated Rejection in Post-Transplant Cardiac Biopsies. Laboratory Investig. 2011; 91(1): 79A. 428. Tatishchey S, Czer L, Kobashigawa J, Luthringer D. Utility of CD68/CD31 Dual Immunostaining Techniques to Detect Antibody-Mediated Rejection in Post-Transplant Cardiac Biopsies. Modern Pathology. 2011; 24(1): 79A. 429. Cao K, Lai C, Ong G, Naim M, Wang Q, Kobashigawa J, Reinsmoen N. Role of Anti-HLA Assessment and Risk Stratification in Heart Transplantation. Human Immunology. 2011; 72(1): S5. 430. Lai C, Masukawa R, Paredes D, Ong G, Wang Q, Nain M, Cao K, Kobashigawa J, Reinsmoen N. C4D + Antibody Mediated Rejection in Absence of Complement Fixing Donor Specific Antibody for a Heart Transplant Patient. Human Immunology. 2011; 72(1): S90. 431. Kawano M, Goldstein Z Hamilton M, Kobashigawa J. Induction vs. non-induction: The saga continues. J Investig Med 2011;59(1):98. 432. Davidoff J, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. Pre-transplant blood transfusion causing sensitization in patients awaiting heart transplantation. J Investig Med 2011;59(1):98-99. 433. Dyo J, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. The long-term benefit of renal sparing protocols demonstrate the lack of need for calcineurin inhibitors. J Investig Med 2011;59(1):99. 434. Geskin A, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. The outcome of African American heart transplant recipients: are they truly at risk. J Investig Med 2011;59(1):99. 435. Moradzadeh N, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. The impact of blood pressure control toward the outcome of heart transplant recipients. J Investig Med 2011;59(1):99. 436. Barry O, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. Does gender mismatch increase the risk of antibody-mediated rejection?. J Investig Med 2011;59(1):99-100. 437. Goldstein Z, Kawano M, Hamilton M, Kobashigawa J. The development of late onset AMR: Does it exist? J Investig Med 2011;59(1):100. 79 CURRICULUM VITAE JON KOB ASHIGAWA, MD 438. Moradzadeh A, Kawano M, Goldstein Z Hamilton M, Kobashigawa J. Low cardiac index in asymptomatic heart transplant patients at one year post transplant does not lead to poor long term outcome. J Investig Med 2011;59(1):211-212. 439. Patel J, Azarbal B, Kittleson M, Kawano M, Goldstein Z, Rafiei M, Moradzadeh A, Czer L, Kass R, Kobashigawa J. Coronary Angioplasty/Stents for Cardiac Allograft Vasculopathy Does Not Alter Outcome for Heart Transplant Patients with ISHLT CAV2 or CAV3 Disease. J Heart Lung Transplant. 2011; 30(4, Supplement): S11. 440. Patel J, Kittleson M, Kawano M, Goldstein Z, Rafiei M, Moradzadeh A, Azarbal B, Czer L, Kass R, Kobashigawa J. Hyperlipidemia from Sirolimus: Adverse Impact on Development of Cardiac Allograft Vasculopathy. J Heart Lung Transplant. 2011; 30(4, Supplement): S12. 441. Kittleson M, Kawano M, Goldstein Z, Rafiei M, Azarbal B, Moriguchi J, Hage A, Reinsmoen N, Reed E, Luthringer D, Esmailian F, Kobashigawa J. Does the Detection of Circulating DonorSpecific Antibody Impact Pathology Diagnosed Antibody-Mediated Rejection after Heart Transplant? J Heart Lung Transplant. 2011; 30(4, Supplement): S17. 442. Patel J, Kittleson M, Kawano M, Goldstein Z, Stimpson E, Rush J, Rafiei M, Reinsmoen N, Reed E, Hamilton M, Trento A, Kobashigawa J. The Effects of Moderate Strength Pre-Transplant Circulating Antibodies on Outcome after Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S21. 443. Kittleson M, Patel J, Kawano M, Goldstein Z, Rafiei M, Reinsmoen N, Reed E, Hage A, Schwarz E, Esmailian, Kobashigawa J. Timing of the Development of Donor Specific Antibody after Heart Transplantation Impacts Long-Term Outcome. J Heart Lung Transplant. 2011; 30(4, Supplement): S22. 444. Kobashigawa J, Pauly D, Ross H, Wang S, Cantin B, Burton J, Keogh A, Eisen H, Lopez P, Dong G, Jiang H, Cines M, Starling R. Reduction of Cardiac Allograft Vasculopathy with Everolimus over Mycophenolate Mofetil: Intravascular Ultrasound Results of a Randomized Multicenter Trial. J Heart Lung Transplant 2011; 30(4, Supplement): S24. 445. Eisen H, Pauly D, Starling R, Lehmkuhl H, Ross H, Kfoury A, Wang S, Cantin B, Van Bakel A, Zuckernmann A, Lopez P, Dong G, Panis C, Jiang H, Cornu-Artis C, Kobashigawa J. Everolimus with Reduced CsA vs MMF with Standard CsA Exposure in De Novo Heart Transplant Recipients: 12 Month Efficacy and Safety Analysis. J Heart Lung Transplant. 2011; 30(4, Supplement): S25. 446. Pauly D, Starling R, Kobashigawa J, Wang S, Cantin B, Keogh A, Lehkuhl H, Hirt S, Lopez P, Dong G, Cines M, Jiang H, Eisen H. Heart Transplant Recipients Treated with Everolimus Have Less Increase in Intimal Thickness vs MMF, Irrespective of Lipid Values. J Heart Lung Transplant. 2011; 330(4, Supplement): S26. 447. Stimpson E, Piponniau L, Patel J, Velleca A, Kawano M, Goldstein Z, Rafiei M, Reinsmoen N, Czer L, Esmailian F, Kobashigawa J. Sorting Out the Intricacies of Multiparity Risk on Outcomes after Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S27. 448. Kao T, Velleca A, Kittleson M, Piponniau L, Rush J, Kawano M, Goldstein Z, Luthringer D, Czer L, Esmailian F, Kobashigawa J. Myth Buster: Does Homogeneous Racial Donor/Recipient Match Improve Outcome after Heart Transplantation? J Heart Lung Transplant. 2011; 30(4, Supplement): S27. 449. Lockhart D, Piponniau L, Velleca A, Patel J, Kittleson M, Kearney B, Kao T, Johnson M, Kawano M, Goldstein Z, Rafiei M, Kobashigawa J. The Life of the Octogenarian Heart Transplant Patient. J Heart Lung Transplant. 2011; 30(4, Supplement): S27. 450. Li F, Lai C, Kobashigawa JA, Fishbein MC, Reed EF. Phosphorylated Signaling Proteins as Biomarkers of Antibody-Mediated Geart Akkigraft Rejection. J Heart Lung Transplant. 2011; 30(4, Supplement): S41. 80 CURRICULUM VITAE JON KOB ASHIGAWA, MD 451. Kobashigawa J, Patel J, Kittleson M, Velleca A, Kawano M, Moradzadeh A, Goldstein Z, Rafiei M, Dyo J, Czer L, Esmailian F. Long-Term Benefit of Renal Sparing Protocols Demonstrate the Lack of Need for Calcineurin Inhibitors. J Heart Lung Transplant. 2011; 30(4, Supplement): S54. 452. Morrissey RP, Czer L, Kittleson M, Patel J, Schwarz E, Jamero G, Kawano M, Rafiei M, Azarbal B, Trento A, Kobashigawa J. Induction vs. Non-Induction in Heart Transplantation: The Controversy Continues. J Heart Lung Transplant. 2011; 30(4, Supplement): S56. 453. Schwarz ERV, Baraghoush A, Phan A, Hamilton MM, Kobashigawa JA, Bharadwaj. Palliative Care Involvement in Advanced Heart Failure Pre and Post Cardiac Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S59. 454. Zuckermann A, Arizon J, Eisen H, Kobashigawa J, Lehmkuhl H, Pellegrini C, Ross H, Karpov A, Barten MJ,. Risk Factors for Pericardial and Pleural Effusions in Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S86. 455. Zuckermann A, Eisen H, Kobashigawa J, Ross H, Wang S, Lehmkuhl H, Rinaldi M, Torre G, Yoman N, Arizon J, Pellegrini C, Lopez P, Dong G, Panis C, Hirt S. Wound Healing Events and Effusions with Everolimus Versus MMF Based Regimens in De Novo Heart Transplant Recipient. J Heart Lung Transplant. 2011; 30(4, Supplement): S87. 456. Patel J, Kawano M, Reed E, Goldstein Z, Rafiei M, Reinsmoen N, Azarbal B, Czer L, Trento A, Kobashigawa J. Circulating Antibody after Heart Transplant and Its Association with Poor Outcome: A Prospective Assessment. J Heart Lung Transplant. 2011; 30(4, Supplement): S87. 457. Patel J, Goldstein Z, Kawano M, Rafiei M, Reinsmoen N, Reed E, Luthringer D, Schwarz E, Trento A, Kobashigawa J. Early Versus Late Antibody-Mediated Rejection: Is There A Difference? J Heart Lung Transplant. 2011; 30(4, Supplement): S87. 458. Velleca A, Piponniau L, Kittleson M, Lockhart D, Kao T, Kearney B, Johnson M, Stimpson E, Rush J, Kawano M, Moreno E, Kobashigawa J. Add to the Cigarette Warning Label: History of Donor Smoking Leads To Increase in Cardiac Allograft Vasculopathy. J Heart Lung Transplant. 2011; 30(4, Supplement): S109. 459. Kittleson M, Patel J, Zakowski P, Czer L, Kobashigawa J. Managing the Threat of DonorTransmitted Amoebic Encephalitis in a Heart Transplant Recipient. J Heart Lung Transplant. 2011; 30(4, Supplement): S132. 460. Yanagida R, Czer LSC, Ruzza A, Vespignani R, Simsir SA, Schwarz ER, De Robertis M, Mirocha J, Coleman B, Runyon C, Jocson R, Olay C, Kass RM, Kobashigawa J, Trento A. Ventricular Assist Device Implantation Provides Opportunity for Significant Weight Loss in Obese Patients with Advanced Heart Failure. J Heart Lung Transplant. 2011; 30(4, Supplement): S162. 461. Piponniau L, Velleca A, Kittleson M, Lockhart D, Kearney B, Kao T, Johnson M, Kawano M, Goldstein Z, Rafiei M, Esmailian F, Kobashigawa J. Seasonal Variations in Cardiac Transplant Antibody-Mediated Rejection. J Heart Lung Transplant. 2011; 30(4, Supplement): S174. 462. Kittleson M, Patel J, Kawano M, Goldstein Z, Rafiei M, Moriguchi J, Reinsmoen N, Reed E, Hage A, Trento A, Kobashigawa J. Pre-Transplant Strength of Circulating Antibody as Expressed in the Calculated Panel Reactive Antibody Score Predicts Antibody-Mediated Rejection after Heart Transplant. J Heart Lung Transplant. 2011; 30(4, Supplement): S175. 463. Patel J, Moriguchi J, Stimpson E, Reinsmoen N, Reed E, Kawano M, Goldstein Z, Rafiei M, Hamilton M, Schwarz E, Kobashigawa J. Success of Desensitization Protocol in Reducing Calculated Panel Reactive Antibodies in a Large Cohort of Sensitized Heart Transplant Candidates. J Heart Lung Transplant. 2011; 30(4, Supplement): S175. 464. Patel J, Kittleson M, Kawano M, Goldstein Z, Rafiei M, Barry O, Hamilton M, Schwarz E, Esmailian F, Kobashigawa J. Does Gender Mismatch Increase the Risk of Antibody-Mediated Rejection (AMR) after Heart Transplantation? J Heart Lung Transplant. 2011; 30(4, Supplement): S178. 81 CURRICULUM VITAE JON KOB ASHIGAWA, MD 465. Kobashigawa J, Patel J, Kittleson M, Kawano M, Hage A, Moradzadeh A, Goldstein Z, Rafiei M, Luthringer D, Schwarz E, Esmailian F. Biopsy-Negative Rejection: An Official New ISHLT Rejection Category? J Heart Lung Transplant. 2011; 30(4, Supplement): S178. 466. Zhang Q, Michael CJ, Gjertson DW, Kobashigawa J, Abbas A, Hickey A, Baas AS, Cruz D, Reed EF. Virtual Crossmatch Significantly Increases Sensitized Patients to Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S180. 467. Patel J, Kittleson M, Kawano M, Goldstein Z, Rafiei M, Davidoff J, Hage Am Reinsmoen N, Schwarz E, Kass R, Kobashigawa J. Contrary to Popular Belief, Pre-Transplant Blood Transfusions Are Uncommon Sensitizing Events in Patients Awaiting Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S181. 468. Kittleson M, Patel J, Kawano M, Goldstein Z, Rafiei M, Moradzadeh A, Moriguchi J, Czer L, Esmailian F, Kobashigawa J. Challenging the ISHLT Guideline Regarding Switch from Mycophenolate to Sirolimus with Standard Dose Calcineurin Inhibitor. J Heart Lung Transplant. 2011; 30(4, Supplement): S182. 469. Kittleson M, Patel J, Esmailian F, Trento A, Kass R, Kawano M, Goldstein Z, Rafiei M, Czer L, Hamilton M, Kobashigawa J. Primary Graft Dysfunction: Autopsy Data Sheds Light on Pathogenesis. J Heart Lung Transplant. 2011; 30(4, Supplement): S194. 470. Kawano M, Kittleson M, Patel J, Goldstein Z, Rafiei M, Moradzadeh N, Moradzadeh A, Hage A, Kobashigawa J. Impact of the Number of Blood Pressure Medications on the Outcome of Heart Transplant Recipients. J Heart Lung Transplant. 2011; 30(4, Supplement): S197. 471. Coleman B, Piponniau L, Patel J, Velleca A, Kawano M, Goldstein Z, Moradzadeh A, Rafiei M, Geskin A, Azarbal B, Kass R, Kobashigawa J. To Be Immunosuppressed, Transplanted, and Black: High Risk for Heart Transplantation. J Heart Lung Transplant. 2011; 30(4, Supplement): S219. 472. Kittleson M, Patel J, Kawano M, Goldstein Z, Barry O, Schwarz E, Czer L, Kobashigawa J. Does Gender Mismatch Increase the Risk of Antibody-Mediated Rejection? J Am Coll Cardiol. 2011; 57: E315 473. White M, Kobashigawa J, Cantin B, Haddad H, Ross H, Carrier M, Pflugfelder P, Isaac D, Cecere R, Whittom L, Ali I, Wang S, Touyz R. Temporal Changes in Cardiac Molecular Events and Biomarkers Following De Novo Cardiac Transplantation. J Am Coll Cardiol. 2011; 57: E318. 474. Eisen HJ, Pauly D, Starling R, Kfoury A, Ross H, Wang S, Cantin B, Hirt S, Lehmkuhl H, Ewald F, Van Bakel A, Zuckermann A, Lopez P, Dong G, Panis C, Jiang H, Cornu-Artis C, Kobashigawa J. Efficacy and Renal Function in De Novo Heart Transplant Recipients Receiving Everolimus with Reduced CsA Compared to MMF with Standard CsA: The A2310 Study. Am J Transplant. 2011; 11(2, Supplement): 129. 475. Bara C, Eisen H, Hirt S, Costard-Jaeckle A, Shulz U, Lopez P, Kobashigawa J, Lehmkul HB. Efficacy and Renal Function in De Novo Heart Transplant Recipients Receiving Everolimus with Reduced CsA Compared to MMF with Standard CsA: The A2310 Study. Transplant International. 2011; 24(3, Supplement): 22. 476. Shulz U, Kobashigawa J, Bara C, Hirt S, Lehmkul HB, Lopez P, Costard-Jaeckle A. CMV Infections are Less Frequent in De Novo Heart Transplant Recipients Receiving Immunosuppression with Everolimus Plus Reduced CsA Compared to MMF and Standard CsA. Transplant International. 2011; 24(3, Supplement): 22. 477. Lehmkuhl H, Kobashigawa J, Bara C, Costard-Jaeckle A, Schulz U, Lopez P, Starling R, Hirt S. Reduction of Cardiac Allograft Vasculopathy with Everolimus Over Mycophenolate Mofetil: Intravascular Ultrasound Results of a Randomized Multicenter Trial. Transplant International. 2011; 24(3, Supplement): 49-50. 478. Hirt S, Wang S, Kobashigawa J, Lehmkuhl H, Rinaldi M, Eisen HJ, Torre Gm Yonan N, Arizon JM, Lopez P, Dong G, Panis C, Zuckermann A. Comparison of Wound Healing Events and 82 CURRICULUM VITAE JON KOB ASHIGAWA, MD Effusions in De Novo Heart Transplant Recipients Treated with Everolimus Versus MMF Based Regimens. Am J Transplant. 2011; 11(2, Supplement): 131. 479. Kobashigawa J, Ross H, Kfoury AG, Van Bakel A, Ewald G, Burton J, Andreassen A, Banchs HL, Segovia J, Lopeszs P, Cines M, Dong G, Potena L. CMV Infections Are Less Frequent in De Novo Heart Transplant Recipients Receiving Immunosuppression with Everolimus Plus Reduced CsA Compared to MMF and Standard CsA. Am J Transplant. 2011; 11(2, Supplement): 131. 480. Starling R, Pauly Dm Wang Sm Cantin B, Ross H, Burton J, Eisen HJ, Keogh A, Dong G, Jiang H, Cines M, Lopez P, Kobashigawa J. De Novo Heart Transplant Recipients at Increased Risk of Cardiac Allograft Vasculopathy: IVUS Analysis of Specific Subpopulations Treated with Everolimus Versus MMF. Am J Transplant. 2011; 11(2, Supplement): 132. 481. Patel J, Kittleson M, Kawano M, Goldstein Z, Rafiei M, Barry O, Hamilton M, Schwarz E, Esmailian F, Kobashigawa J. Male Donor to Female Recipient in Heart Transplantation Increases the Risk of Antibody-Mediated Rejection. Am J Transplant. 2011; 11(2, Supplement): 237. 482. Patel J, Kittleson M, Goldstein Z, Kawano M, Rafiei M, Reed E, Reinsmoen N, Schwarz E, Kass R, Kobashigawa J. Virtual Crossmatch and Desensitization Therapy Has Reduced Time to Transplant for Sensitized Patients. Am J Transplant. 2011; 11(2, Supplement): 237. 483. Kobashigawa J, Patel J, Kittleson M, Kawano M, Hage A, Moradzadeh A, Goldstein Z, Rafiei M, Luthringer D, Schwarz E, Esmailian F. The Category of Biopsy-Negative Rejection in Heart Transplantation. Am J Transplant. 2011; 11(2, Supplement): 238. 484. Kittleson M, Patel J, Esmailian F, Trento A, Kass R, Kawano M, Goldstein Z, Rafiei M, Czer L, Hamilton M, Kobashigawa J. Primary Graft Dysfunction and Autopsy Findings. Am J Transplant. 2011; 11(2, Supplement): 238. 485. Patel J, Azarbal B, Goldstein Z, Rafiei M, Kawano M, Moradzadeh A, Kittleson M, Czer L, Trento A, Kobashigawa J. Screening Nuclear Stress Testing as a Prognostic Marker after Heart Transplantation. Am J Transplant. 2011; 11(2, Supplement): 303. 486. Junge G, Witte S, Zuckermann A, Lehmkuhl H, Schwende H, Wang Z, Kobashigawa J. Everolimus, mTORC1 Signaling and Evolution of Body Weight after Cardiac Transplantation. Am J Transplant. 2011; 11(2, Supplement): 304. 487. Junge G, Witte S, Zuckermann A, Lehmkuhl H, Schwende H, Wang Z, Kobashigawa J. Everolimus, mTORC1 Signaling and Evolution of Body Weight after Cardiac Transplantation. Transplant International. 2011; 24(3, Supplement): 5. 488. Azarbal B, Wei J, Singh S, Currier J, Patel J, Hage A, Makkar R, Kobashigawa J. Frequency of coronary artery fistulae and extracardiac neovascularization after orthotopic heart transplantation. Circulation. 2011 Nov 22; 124 (21) S-A14063. 489. Rafiei M, Stern LK, Patel N, Hamilton M, Kobashigawa J. Lack of correlation of first-year cylex scores to the development of cardiac allograft vasculopathy suggests the importance of humoral factors. J Investig Med. 2012; 60(1): 172. 490. Shiozaki R, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. First-year brain natriuretic peptide (BNP) as a biomarker after heart transplant for poor outcome and prediction of the severity of cardiac allograft vasculopathy (CAV). J Investig Med. 2012; 60(1) 172-173. 491. Patel N, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. Obesity and protection from cardiac allograft vasculopathy: Is the myth true? J Investig Med. 2012; 60(1): 173. 492. Patel DP, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. The policy of placing older donors into older recipients: Is it worth it? J Investig Med. 2012; 60(1): 173-174. 493. Merz A, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. Has the virtual crossmatch truly decreased time on the heart transplant waiting list for sensitized patients? J Investig Med. 2012; 60(1): 174. 83 CURRICULUM VITAE JON KOB ASHIGAWA, MD 494. Stern LK, Rafiei M, Patel DP, Hamilton M, Kobashigawa J. Infectious complications of desensitization therapy: Is the cure worse that the disease? J Investig Med. 2012; 60(1): 174. 495. Tang Z, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. The natural history of biopsy negative rejection after heart transplantation. J Investig Med. 2012; 60(1): 174. 496. Lee D, Rafiei M, Stern LK, Hamilton M, Kobashigawa J. Tricuspid regurgitation in the first year after heart transplant: Does it mean gloom and doom? J Investig Med. 2012; 60(1): 175. 497. Kwon M, Zhang Q, Abrahamyan A, Zhang Z, Gjertson D, Ardehali A, Kobashigawa J, Shemin R, Reed E. Characterization of Ventricular Assist Device Mediated Sensitization in the Bridge to Heart Transplant Patient. Circ Research. 2012; 109(12): AP122 498. Kai B, Patel J, Kittleson M, Czer L, Trento A, Esmailian F, Kobashigawa J. Does persistent firstyear low of high cardiac index results in poor outcomes after heart transplantation? J Am Coll Cardiol 2012; 59(13): E990 499. Perkel D, Patel J, Kittleson M, Chang D, Czer L, Esmailian F, Kobashigawa J. CMV infection in the era of tacrolimus/mycophenolate: Is there still an impact to develop cardiac allograft vasculopathy? J Am Coll Cardiol 2012; 59(13): E923 500. Tadwalkar R, Patel J, Kittleson M, Czer L, Kobashigawa J. Consequences of first-year rejection after heart transplantation: Is the worse yet to come? J Am Coll Cardiol 2012; 59(13): E992 501. Chai W, Patel J, Kittleson M, Czer L, Rafiei M, Stern L, Esmailian F, Kobashigawa J. Risk for deep vein thrombosis and pulmonary embolism after heart transplantation: Characterization of an old problem. J Am Coll Cardiol 2012; 59(13): E922 502. Sue E, Patel J, Kittleson M, Czer L, Trento A, Esmailian F, Kobashigawa J. Does strict diabetic control after heart transplantation lead to better outcome? J Am Coll Cardiol 2012; 59(13): E930 503. Kobashigawa J, Patel J, Rafiei M, Stern L, Kittleson M, Czer L, Esmailian F. Late Response to Desensitization Therapy. J Heart and Lung Transplant. 2012; 31(4): S158 504. Patel J, Kittleson M, Rafiei M, Stern L, Chang D, Czer L, Trento A, Kobashigawa J. Desensitization Therapy with Immunoglobulin (IVIG) and Rituximab for Patients Awaiting Heart Transplantation. J Heart and Lung Transplant. 2012; 31(4): S161 505. Cao K, Lai CH, Flores S, Rafiei M, Mirocha J, Haas M, Ong G, Naim M, Wang Q, Constanza L, Patel J, Reinsmoen N, Kobashigawa J. Anti-Angiotensin Type 1 Receptor (AT1R) Antibodies Together with Anti-HLA Donor Specific Antibodies (HLA-DSA) Identify Patients at Risk for Immune Complication in Heart Transplant. J Heart and Lung Transplant. 2012; 31(4): S163 506. Rafiei M, Patel J, Kittleson M, Patel N, Stern L, Azarbal B, Czer L, Trento A, Kobashigawa J. First-Year Rejection and Cylex Scores Suggest the Importance of Acute Events in the Development of Cardiac Allograft Vasculopathy. J Heart and Lung Transplant. 2012; 31(4): S168 507. Stern L, Patel J, Kittleson M, Rafiei M, Dilibero D, Hage A, Czer L, Kobashigawa J. Use of Generic Immunosuppression: Does it Truly Matter? J Heart and Lung Transplant. 2012; 31(4): S203 508. Kearney B, Chai W, Patel J, Kittleson M, Rafiei M, Stern L, Czer L, Kobashigawa J. Does Level of Education Affect Outcome After Heart Transplantation? J Heart and Lung Transplant. 2012; 31(4): S203-S204 509. Patel J, Shiozaki R, Rafiei M, Stern L, Kittleson M, Chang D, Czer L, Esmailian F, Kobashigawa J. Application of Immunosuppression Clinical Trial Results in Reducing the Incidence of Heart Transplant Rejection-Bridging the New Millennium. J Heart and Lung Transplant. 2012; 31(4): S24 510. Patel J, Kittleson M, Czer L, Rafiei M, Stern L, Patel DP, Hage A, Esmailian F, Kobashigawa J. The Policy of Placing Older Donors into Older Recipients: Is it Worth it? J Heart and Lung Transplant. 2012; 31(4): S24-S25 84 CURRICULUM VITAE JON KOB ASHIGAWA, MD 511. Czer L, Patel J, Kittleson M, Rafiei M, Stern L, Chang D, Luthringer D, Esmailian F, Kobashigawa J. Consequences of First-Year Rejection after Heart Transplantation: Is the Worse yet to Come? J Heart and Lung Transplant. 2012; 31(4): S25 512. Patel J, Kittleson M, Czer L, Rafiei M, Stern L, Esmailian F, Reinsmoen N, Kobashigawa J. Are Donor Specific Antibodies Detected after Heart Transplant All Bad? J Heart and Lung Transplant. 2012; 31(4): S35 513. Patel J, Kittleson M, Rafiei M, Stern L, Patel N, Czer L, Esmailian F, Kobashigawa J. Resurgence of Photopheresis for Recalcitrant Cellular and Antibody-Mediated Cardiac Allograft Rejection. J Heart and Lung Transplant. 2012; 31(4): S223 514. Czer L, Patel J, Kittleson M, Rafiei M, Stern L, Chang D, Trento A, Kobashigawa J. Combined Heart-Kidney Transplant Compared to Heart Transplant Alone May Reduce Long Term Development of Cardiac Allograft Vasculopathy. J Heart and Lung Transplant. 2012; 31(4): S229 515. Moriguchi J, Patel J, Kittleson M, Rafiei M, Stern L, Czer L, Trento A, Kobashigawa J. Older Patients with Hemodynamic Compromise Rejection: What Happened to Immunosenescence? J Heart and Lung Transplant. 2012; 31(4): S233 516. Czer L, Lee D, Patel J, Kittleson M, Rafiei M, Stern L, Hage A, Esmailian F, Trento A, Kobashigawa J. Tricuspid Regurgitation in the First-Year after Heart Transplant: Does it Lead to Gloom and Doom? J Heart and Lung Transplant. 2012; 31(4): S233-S234 517. Patel J, Kittleson M, Rafiei M, Stern L, Tang Z, Chang D, Luthringer D, Czer L, Trento A, Kobashigawa J. The Natural History of Biopsy Negative Rejection after Heart Transplantation. J Heart and Lung Transplant. 2012; 31(4): S235 518. Moriguchi J, Patel J, Kittleson M, Rafiei M, Stern L, Chai W, Chang D, Trento A, Czer L, Kobashigawa J. Risk for Deep Vein Thrombosis and Pulmonary Embolism after Heart Transplantation: Characterization of an Old Problem. J Heart and Lung Transplant. 2012; 31(4): S235 519. Kobashigawa J, Patel J, Kittleson M, Rafiei M, Stern L, Czer L, Reinsmoen N, Esmailian F. AntiHLA DQ Antibodies: Does Strength of Antibody Result in Subsequent Greater Cardiac Allograft Vasculopathy? J Heart and Lung Transplant. 2012; 31(4): S235-S236 520. Kansara P, Kransdorf E, Kittleson M, Patel J, Coleman B, Jamero G, Runyan C, Olay C, Jocson R, Czer L, Trento A, Kass R, Esmailian F, Kobashigawa J, Moriguchi J. Improved Outcomes in “Crash and Burn” Patients through BiVAD Support. J Heart and Lung Transplant. 2012; 31(4): S267S268 521. Kobashigawa J, Pauly D, Kfoury A, Ross H, Wang SS, Cantin B, Van Bakel A, Starling R, Hirt S, Dong G, Panis C, Lopez P, Eisen H. Multicenter Randomized Trial of Everolimus vs. Mycophenolate Mofetil in Heart Transplantation: Final 24 Month Analysis of Efficacy and Safety. J Heart and Lung Transplant. 2012; 31(4): S75 522. Coleman B, Patel J, Czer L, Mirocha J, Kobashigawa J. Use of Thymoglobulin after Heart Transplantation: Is there a Role in African American Patients? J Heart and Lung Transplant. 2012; 31(4): S92-S93 523. 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First-Year Brain Natriuretic Peptide (BNP) as a Biomarker after Heart Transplant to Predict Severity of Cardiac Allograft Vasculopathy (CAV) as per the new ISHLT CAV Scale. J Heart and Lung Transplant. 2012; 31(4): S122 527. Kobashigawa J, Pauly D, Kfoury A, Ross H, Wang SS, Cantin B, vanBakel A, Starling R, Hirt S, Dong G, Panis C, Lopez P, Eisen H. Effect of Everolimus Based Immunosuppression on De Novo Heart Transplant Recipients-24 Months Efficacy and Safety Results from A2310 Study. Am J Transplant. 2012; 12 (Suppl 3): 67-68 528. Patel J, Kittleson M, Czer L, Rafiei M, Stern L, Reinsmoen N, Kobashigawa J. Maintenance Immunosuppression and De Novo Antibody Production after Heart Transplantation: Does the Choice of Drugs Matter? Am J Transplant. 2012; 12 (Suppl 3): 73-74 529. Patel J, Kittleson M, Czer L, Rafiei M, Stern L, Patel DP, Hage A, Esmailian F, Kobashigawa J. The Policy of Placing Older Donors into Older Recipients: Is it Worth it? 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Is Hormone Replacement Therapy (HRT) in Postmenopausal Women Associated with Poor Outcome after Heart Transplantation? Am J Transplant. 2012; 12 (Suppl 3): 477 535. Kobashigawa J, Patel J, Kittleson M, Rafiei M, Stern L, Czer L, Reinsmoen N, Esmailian F. AntiHLA DQ Antibodies: Does Strength of Antibody Result in Subsequent Greater Cardiac Allograft Vasculopathy? Am J Transplant. 2012; 12 (Suppl 3): 382 536. Moriguchi J, Kittleson M, Patel J, Coleman B, Jamero G, Runyan C, Olay C, Jocson R, Chang D, Czer L, Trento A, Esmailian F, Kobashigawa J. Are Sensitized VAD Patients Similar to Sensitized non-VAD Patients in Terms of Outcome? Am J Transplant. 2012; 12 (Suppl 3): 120-121 537. Kansara P, Czer L, Patel J, Kittleson M, Mirocha J, Moriguchi J, Chang D, De Robertis M, Trento A, Kass R, and Kobashigawa J. Prior Cardiac Surgery is a Predictor of Mortality in the First-Year in Heart Transplant Recipients. Am J Transplant. 2012; 12 (Suppl 3): 476 538. 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Dhiantravan V, Patel J, Kittleson M, Rafiei M, Osborne A, Chang D, Czer L, Kobashigawa J. Mycophenolate not Azathioprine with Increased Risk for Skin Cancer after Heart Transplant. J Am College of Cardiology. 2013; 61(10) Suppl A: 195 552. Geft D, Patel J, Kittleson M, Chang D, Rafiei M, Osborne A, Czer L, Esmailian F, Kobashigawa J. Use of Cylex Immune Monitoring Score to Guide Immunosuppression After Heart Transplantation Reduces Infection Risk. J Am College of Cardiology. 2013; 61(10) Suppl A: 196 553. Kansara P, Czer L, Patel J, Mirocha J, Kittleson M, De Robertis M, Moriguchi J, Chang D, Ramzy D, Kass R, Esmailian F, Trento A, Kobashigawa J. Early Mortality and Morbidity in Heart Transplant Recipients with Prior History of Cardiac Surgery: Analysis of United Network for Organ Sharing Database. J Am College of Cardiology. 2013; 61(10) Suppl A: 196 554. Tadwalkar R, Kittleson M, Patel J, Moriguchi J, Rafiei M, Osborne A, Chang D, Czer L, Esmailian F, Reinsmoen N, Kobashigawa J. 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Kittleson M, Stewart F, Cowger J, Patel C, Rame E, Testani J, Mountis M, Patel P, Johnson F, Guglin M, Teuteberg J, Kobashigawa J, Stevenson L, Hamilton M. Triage for Advanced Heart Failure: Effect of Regional Wait Time Disparity. J Heart and Lung Transplant. 2013; 32(4): S166-S167 567. Patel J, Kittleson M, Rafiei M, Osborne A, Aaronson A, Chang D, Azarbal B, Czer L, Moriguchi J, Kobashigawa J. Benefit of Tacrolimus/Myocophenolate to Reduce Cardiac Allograft Vasculopathy after Heart Transplantation. J Heart and Lung Transplant. 2013; 32(4): S50 568. Kobashigawa J, Tadwalkar R, Kittleson M, Patel J, Moriguchi J, Rafiei M, Osborne A, Chang D, Czer L, Esmailian F, Reinsmoen N. Establishing a PRA Threshold to treat Sensitized Patients Awaiting Heart Transplant in the Era of the Virtual Crossmatch. J Heart and Lung Transplant. 2013; 32(4): S53 569. Patel J, Kittleson M, Rafiei M, Osborne A, Chang D, Czer L, Kobashigawa J. Proliferation Signal Inhibitors Reduce Severity of Cardiac Allograft Vasculopathy after Heart Transplantation. J Heart and Lung Transplant. 2013; 32(4): S50 570. Kobashigawa J, Starling R, Dong G, Lopez P, Eisen H. Change in Maximum Intimal Thickness with Everolimus-based Immunosuppression after Heart Transplantation in Patients at Increased Risk of Cardiac Allograft Vasculopathy. J Heart and Lung Transplant. 2013; 32(4): S25-S26 571. Kittleson M, Patel J, Rafiei M, Osborne A, Jamero G, Chang D, Azarbal B, Czer L, Kobashigawa J. Even Mild Renal Insufficiency is a Risk for Mortality after Heart Transplant. J Heart and Lung Transplant. 2013; 32(4): S40 88 CURRICULUM VITAE JON KOB ASHIGAWA, MD 572. Patel J, Kittleson M, Rafiei M, Osborne A, Chang D, Czer L, Esmailian F, Reinsmoen N, Kobashigawa J. The incidence of circulating antibodies at the time of Pathology Defined Antibody-Mediated Rejection after Heart Transplantation. J Heart and Lung Transplant. 2013; 32(4): S20-2S21 573. 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Coronary Artery Fistulae after Orthotopic Heart Transplantation are Associated with Decreased Prevalence of Transplant Coronary Artery Disease. J Heart and Lung Transplant. 2013; 32(4): S210-211 577. Kittleson M, Patel J, Rafiei M, Osborne A, Shiozaki R, Chang D, Moriguchi J, Czer L, Kobashigawa J. Failed Prednisone Taper Off after heart transplant: Is there a price to be paid? J Heart and Lung Transplant. 2013; 32(4): S200 578. Rush J, Kittleson M, Patel J, Rafiei M, Osborne A, Velleca A, Piponniau L, Chang D, Czer L, Kobashigawa J. Men Versus Women: Outcome Differences on Cyclosporine and Tacrolimus. J Heart and Lung Transplant. 2013; 32(4): S201 579. Piponniau L, Kittleson M, Patel J, Rafiei M, Osborne A, Dhiantravan V, Chang D, Czer L, Hage A, Hamilton M, Moriguchi J, Kobashigawa J. Mycophenolate not Azathioprine is Associated with Increased Risk for Skin Cancer after Heart Transplant. J Heart and Lung Transplant. 2013; 32(4): S199 580. 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Acyclovir neurotoxicity in an orthotropic heart transplant patient on peritoneal dialysis. Annals of Int Med 2013; In Press. 618. Parikh A, Yu Z, Liou F, Hamilton M, Kobashigawa J. Beta Blockers to Lower Heart Rate After Heart Transplantation May Not Be Beneficial. J Investig Med. 2014;62(1):273 619. Liou F, Yu Z, Hamilton M, Kobashigawa J. Does Heart-Kidney Transplant confer Protective Benefits in Immune Responses? J Investig Med. Jan 2014;62(1):158 620. Wong D, Yu Z, Liou F, Yabuno J, Hamilton M, Kobashigawa J. Cylex Scores for African Americans vs. Caucasians: Is There a Difference? J Investig Med. 2014;62(1):274 621. Yabuno J, Yu Z, Liou F, Hamilton M, Kobashigawa J. Is a Lower Cylex Score Helpful in Preventing the Development of Circulating Antibodies After Heart Transplant? J Investig Med. 2014;62(1):272 622. Murayama K, Yu Z, Liou F, Hamilton M, Kobashigawa J. Donor Height vs. Weight: Is One More Important Than the Other? J Investig Med. 2014;62(1):202 623. Yu Z, Liou F, Hamilton M, Kobashigawa J. A Natural History of Pericardial Effusion After Heart Transplantation. J Investig Med. 2014;62(1):272 624. Aquino A, Yu Z, Liou F, Hamilton M, Kobashigawa J. Do Redo Heart Transplant Patients Have an Increased Risk of Antibody Development? J Investig Med. 2014;62(1):273 625. Chehrazi-Raffle A, Yu Z, Liou F, Hamilton M, Kobashigawa J. Toxoplasma Serology and Outcomes after Heart Transplantation: Contention in the Literature. J Investig Med. 2014;62(1):158 626. Siu M, Yu Z, Liou F, Hamilton M, Kobashigawa J. Ventricular Assist Device Complications on the Waiting List and Post-Heart Transplant Outcomes. J Investig Med. 2014;62(1):192,202 627. Ngan A, Yu Z, Liou F, Hamilton M, Kobashigawa J. Sensitized Ventricular Assist Device Patients vs. Sensitized Non-Ventricular Assist Device Patients: Is There an Immunological Difference? J Investig Med. 2014;62(1):202 628. Kai B, Reinsmoen N, Yu Z, Liou F, Yabuno J, Patel J, Kittleson M, Hamilton M, Chang D, Czer L, Kobashigawa J. Does Anything Work for the Highly Sensitized Patients Awaiting Heart Transplant? Am Coll Cardiol. 2014; 63 (12_S) 629. Cheng R, Azarbal B, Patel J, Chang D, Kobashigawa J. Elevated Immune Monitoring after Cardiac Transplantation is Associated with Increased Plaque Progression by Intravascular Ultrasound. Am Coll Cardiol. 2014; 63 (12_S) 630. Grigorian-Shamajan L, Yu Z, Liou F, Patel J, Kittleson M, Azarbal B, Chang D, Czer L, Kobashigawa J. Percutaneous Coronary Intervention versus Medical Therapy for Moderate Coronary Lesions after heart Transplantation: What to do? Am Coll Cardiol. 2014; 63 (12_S) 631. Gurudevan S, Arabia F, Esmailian, Ramzy D, Czer L, Kobashigawa J, Moriguchi J. The Total Artificial Heart: An Effective Bridge to Transplantation in Patients with Advanced Heart Failure. Am Coll Cardiol. 2014; 63 (12_S) 632. Kafi A, Patel J, Kittleson M, Yu Z, Liou F, Yabuno J, Kao T, Czer L, Chang DH, Hage A, Ramzy D, Kobashigawa J. Abnormal Pulmonary Function Tests Contraindicate Heart Transplant. J Heart Lung Transplant. 2014; 33(4): S141-142 92 CURRICULUM VITAE JON KOB ASHIGAWA, MD 633. Kittleson M, Patel J, Yu Z, Liou F, Aquino A, Velleca A, Czer L, Chang DH, Hamilton M, Trento A, Reinsmoen N, Kobashigawa J. Do Redo Heart Transplant Patients Have an Increased Risk of Antibody Development? J Heart Lung Transplant. 2014; 33(4): S284 634. Lipson-Altman N, Reinsmoen N, Kittleson M, Luthringer D, Patel J, Liou F, Yu Z, Kearny B, Czer L, Chang DH, Ramzy D, Kobashigawa J. Does the Ability for Donor Specific Antibodies to Bind Complement Always Result in C4d Staining in the Endomyocardial Biopsy After Heart Transplant? J Heart Lung Transplant. 2014; 33(4): S83 635. Moriguchi J, Arabia F, Patel J, Kittleson M, Yu Z, Liou F, Yabuno J, Chang DH, Czer L, Hage A, Ramzy D, Kobashigawa J. Does VAD Placement Reduce Weight in Obese Severe Heart Failure Patients? J Heart Lung Transplant. 2014; 33(4): S209 636. Moriguchi J, Arabia F, Jocson R, Patel J, Kittleson M, Liou F, Yu Z, Ernst W, Hamilton M, Chang DH, Czer L, Kobashigawa J. Extracorporeal membrane Oxygenation as a Bridge to Decision for INTERMACS 1 Patients. J Heart Lung Transplant. 2014; 33(4): S250-251 637. Stimpson E, Dilibero D, Kittleson M, Patel J, Yu Z, Liou F, Yabuno J, Zakowski P, Czer L, Trento A, Esmailian F, Kobashigawa J. Hepatitis B Vaccination Confers an Increased Rate of Transplant for Patients on the Heart Transplant Waiting List. J Heart Lung Transplant. 2014; 33(4): S268 638. Sasevich MJ, Esmailian F, Rihbany K, Pouldar T, Yu Z, Liou F, Ramzy D, Arabia F, Trento A, Czer L, Hamilton M, Kobashigawa J. Is Pre-Existing Liver Cirrhosis and Fibrosis a Contraindication to Heart Transplantation? J Heart Lung Transplant. 2014; 33(4): S157 639. Kobashigawa J, Moriguchi J, Reinsmoen N, Kittleson M, Yu Z, Liou F, Ngan A, Runyan M, Henry H, Chang DH, Czer L, Arabia F. Sensitized VADs vs. Sensitized Non-VADs: Is There an Immunological Difference? J Heart Lung Transplant. 2014; 33(4): S305 640. Yu Z, Patel J, Kittleson M, Liou F, Yabuno J, Jamero G, Chang DH, Czer L, Azarbal B, Trento A, Esmailian F, Kobashigawa J. The Risk of Prior Chest Radiation Therapy in Patients Who Undergo Heart Transplantation. J Heart Lung Transplant. 2014; 33(4): S170-171 641. Kittleson M, Chehrazi-Raffle A, Patel J, Yu Z, Liou F, Johnson M, Stimpson E, Hage A, Chang DH, Czer L, Zakowski P, Kobashigawa J. Toxoplasma Serology Mismatch with Increased Mortality? Clarifying the Literature. J Heart Lung Transplant. 2014; 33(4): S179-180 642. Reinsmoen N, Haas M, Patel J, Lai C, Naim M, Ong G, Wang Q, Mirocha J, Yu Z, Liou F, Kobashigawa J. Does the Presence of Complement Binding De Novo DSA Distinguish Different Pathology Defined Rejection Patterns in Heart Transplant Recipients? J Heart Lung Transplant. 2014; 33(4): S283 643. Patel J, Kittleson M, Yu Z, Liou F, Yabuno J, Aggarwal C, Kearny B, Chang DH, Czer L, Esmailian F, Kobashigawa J. Proliferative Signal Inhibitors and Deep Vein Thrombosis: Is There a Connection? J Heart Lung Transplant. 2014; 33(4): S276-277 644. Balasubramanya S, Arabia F, Trento A, Ramzy D, Chang DH, Kittleson M, Czer L, Moriguchi J, Kobashigawa J. Extracorporeal Membrane Oxygenation as a Bridge to Recovery, Bridge to Ventricular Assist Device and Bridge to Heart Transplantation: A Retrospective Review of Data from a Single Tertiary Care Institution. J Heart Lung Transplant. 2014; 33(4): S78 645. Coleman B, Phillips A, Mirocha J, Patel J, Arabia F, Kobashigawa J. Antithymocyte Globulin But Not Basiliximab Is Beneficial After Infant Heart Transplantation – Analysis of the UNOS Database. J Heart Lung Transplant. 2014; 33(4): S123 646. Coleman B, Phillips A, Mirocha J, Patel J, Arabia F, Kobashigawa J. Induction Therapy in African American Infant Heart Transplants: Is There a Benefit? J Heart Lung Transplant. 2014; 33(4): S43 93 CURRICULUM VITAE JON KOB ASHIGAWA, MD 647. Kransdorf E, Kittleson M, Coleman B, Hoffman D, Berkman S, Ramzy D, Steidley DE, Kobashigawa J. Atypical Hemolytic-Uremic Syndrome Immediately Following Heart Transplantation. J Heart Lung Transplant. 2014; 33(6): 664-665 648. Cheng R, Azarbal B, Patel J, Kittleson M, Kobashigawa J. Early Immune Monitoring After Cardiac Transplantation Predicts Progression of Maximal Intimal Thickness by Intravascular Ultrasound. J Heart Lung Transplant. 2014; 33(4): S24 649. Cheng R, Azarbal B, Patel J, Wei J, Kobashigawa J. Presence of Coronary Artery Fistulae after Cardiac Transplantation Is Associated with Increased Plaque Progression by Intravascular Ultrasound. J Heart Lung Transplant. 2014; 33(4): S284 650. Ardehali A, Esmailian F, Deng M, Soltesz E, Hsich E, Naka Y, Mancini D, Camacho M, Baran D, Zucker, Leprince P, Madsen J, Tsui S, Simon A, Livi U, Guzzi G, Kobashigawa J. The Proceed II International Heart Transplant Trial with the Organ Care System (OCS™) Technology. J Heart Lung Transplant. 2014; 33(4): S118 651. Ardehali A, Mancini D, Naka Y, Kobashigawa J, Esmailian F, Hsich E, Soltesz E, Deng M. Heart Transplantation After Ex-Vivo Perfusion of the Donor Hearts: Does it Affect Inotropic Use and Hospital Stay? J Heart Lung Transplant. 2014; 33(4): S117 652. Doering L, Hickey K, Chen B, Idemundia F, Carter E, Pickham D, Castillo C, Mancini D, Deng M, Kobashigawa J. Perceived Control: A Target for Improving Psychosocial Outcomes Early After Heart Transplant. J Heart Lung Transplant. 2014; 33(4): S32-33 653. Kobashigawa J, Grskovic M, Dedrick R, Gundel K, Woodward R, Vanhaecke J, Crespo-Leiro MG, Stypmann J, Deng MC, Starling R. Increased Plasma Levels of Graft-Derived Cell-Free DNA Correlate with Rejection in Heart Transplant Recipients. J Heart Lung Transplant. 2014; 33(4): S14 654. Selby VN, Mundayat R, Maurer M, Stern L, Klein L, Janmohamed M, Kobashigawa J, Kobes RD, De Marco T. Survival Following Heart Transplantation in Patients with Transthyretin Amyloid Cardiomyopathy. J Heart Lung Transplant. 2014; 33(4): S177-178 655. Moriguchi J, Arabia F, Kittleson M, Patel J, Yu Z, Liou F, Ernst W, Huie N, Hage A, Chang D, Czer L, Kobashigawa J. Heart Transplantation vs. Ventricular Assist Device as Destination Therapy in Older Patients: Are They Comparable? Am J Transplant. 2014; 14(S3): 52 656. Arabia F, Moriguchi , Jocson R, Kittleson M, Patel J, Yu Z, Liou F, Chang D, Czer L, Ramzy D, Esmailian F, Kobashigawa J. Single Center Experience of Total Artificial Heart as a Bridge to Heart Transplantation. Am J Transplant. 2014; 14(S3): 52 657. Kittleson M, Reinsmoen N, Patel J, Liou F, Yu Z, Luu M, Hamilton M, Hage A, Azarbal A, Kobashigawa J. Heart Transplantation across Low Level Donor Specific c Antibodies: Is It Bad? Am J Transplant. 2014; 14(S3): 53 658. Watanabe J, Shafi H, Patel J, Klapper E, Yu Z, Krivitskiy I, Liou F, Kittleson M, Jordan S, Kobashigawa J, Toyoda M. Extracorporeal Photopheresis (ECP) Improved Allograft Function and Significantly Reduced Inflammatory Cytokines in Patients (Pts) With Refractory Heart Allograft Dysfunction. Am J Transplant. 2014; 14(S3): 56 659. Kittleson M, Patel J, Hamilton M, Yu Z, Liou F, Yabuno J, Azarbal B, Chang D, Geft D, Kobashigawa J. Anti-Thymocyte Globulin Induction to Prevent Renal Dysfunction: Is It Necessary Today? Am J Transplant. 2014; 14(S3): 56 660. Coleman B, Phililps A, Mirocha J, Patel J, Kobashgawa J. Induction Therapy in Pediatric Heart Transplantation: Is There a Benefit? Globulin Induction to Prevent Renal Dysfunction: Is It Necessary Today? Am J Transplant. 2014; 14(S3): 57 661. Esmailian F, Kobashigawa J, Thottam M, Yu Z, Liou F, Patel J, Kittleson M, Czer L, Trento A. Heart in the Box With Good 1-Year Outcome Post Heart Transplantation. Am J Transplant. 2014; 14(S3): 58 94 CURRICULUM VITAE JON KOB ASHIGAWA, MD 662. Patel J, Kittleson M, Ramzy D, Yu Z, Liou F, Yabuno J, Arabia F, Moriguchi J, Czer L, Kobashigawa J. Perioperative Bleeding Risk of Anti-Platelet Therapy Prior to Heart Transplant. Am J Transplant. 2014; 14(S3): 59 663. Azarbal B, Chang D, Esmailian F, Arabia F, Moriguchi J, Kobashigawa J, Makkar R. No Survival Benefit with Use of Intra-Aortic Balloon Pump in Extracorporeal Membrane Oxygenation: A Pooled Experience of 1,517 Patients. J Am Coll Cardiol. 2014;64(11_S) 664. Arbit B, Azarbal B, Vanichsarn C, Chang D, Patel J, Kobashigawa J, Makkar R. Long Term Clinical and Angiographic Outcomes with Everolimus-Eluting Stents for Cardiac Allograft Vasculopathy. J Am Coll Cardiol. 2014;64(11_S) 665. Chang R, Yung A, Azarbal B, Patel J, Kobashigawa J. Early Stenosis on Intravascular Ultrasound Immediately After Cardiac Transplantation Predicts Downstream Development of Transplant Coronary Artery Disease. J Am Coll Cardiol. 2014;64(11_S) 666. Rush J, Johnson M, Kao T, Patel J, Liou F, Yu Z, Luu M, Chang M, Czer L, Trento A, Esmailian F, Kobashigawa J. Risk of High Risk Donors in Heart Transplantation Am J Transplant. 2014; 14(S3): 424 667. Reich H, Awad M, Sasevich M, Nissen N, Colquhoun S, Esmailian F, Trento A, Kobashigawa J, L Czer. Combined Heart and Liver Transplantation in a High-Volume Transplant Center: The Cedars-Sinai Experience. Am J Transplant. 2014; 14(S3): 424 668. Liou F, Patel J, M. Kittleson, Yu Z, Luu M, Piponniau L, Luthringer D, Czer L, Chang D, Hamilton M, Esmailian F, Kobashigawa J. Does Heart-Kidney Transplant Truly Confer Protective Benefit Against Rejection? Am J Transplant. 2014; 14(S3): 424 669. 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Patel J, Kittleson M, Moriguchi J, Liou F, Yu Z, Yabuno J, Azarbal B, Chang D, Czer L, Kobashigawa J. Cyclosporine vs. Tacrolimus: Which Is a Better Match With Everolimus? Am J Transplant. 2014; 14(S3): 430 674. G. Jamero, M. Kittleson, J. Patel, F. Liou, Z. Yu, D. Dilibergo, N. Perry, D. Chang, L. Czer, A. Hage, F. Esmailian, Kobashigawa J. Are First Year Mycophenolate Trough Levels Associated With the Subsequent Outcomes After Heart Transplant? Am J Transplant. 2014; 14(S3): 432 675. Yabuno J, Patel J, Kittleson M, Yu Z, Liou F, Chang D, Czer L, Hamilton M, Trento A, Reinsmoen N, Esmailian F, Kobashigawa J. A Lower Cylex Score May Be a Useful Tool to Prevent the Development of Circulating Antibodies After Heart Transplantation? Am J Transplant. 2014; 14(S3): 432 676. Choi S, Grein J, Kobashigawa J, Jordan S, Zakowski, P. Late-Onset Pneumocystis Pneumonia in Kidney and Heart Transplant Recipients. Am J Transplant. 2014; 14(S3): 628 95 CURRICULUM VITAE JON KOB ASHIGAWA, MD 677. Fong A, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. The Prevolance of Donor Specific Anti-HLA Antibodies Late after Heart Transplant. J Investig Med. 2015; 63(1):87 678. Assad N, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. Does the Development of Bw4 and Bw6 Antibodies Confer Poorer Outcomes in Heart Transplant Patients? J Investig Med. 2015; 63(1):87 679. Luu M, Aintablian T, Liou F, Hamilton M, Kobashigawa J. Cylex Fails to Improve Predictive Value of Allomap for Cardiac Allograft Rejection. J Investig Med. 2015; 63(1):88 680. Aintablian T, Liou F, Luu M, Hamilton M, Kobashigawa J. Antibody Production does Not Appear to be Important in TAH Patients Despite More Blood Transfusions. J Investig Med. 2015; 63(1):112 681. Patel P, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. Benefit of Renal Sparing Protocol Across Time Post Heart Transplantation. J Investig Med. 2015; 63(1):113 682. Shiozaki R, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. The Time Course of Anti-HLA Antibody Development Following Heart Transplantation. J Investig Med. 2015; 63(1):113-114 683. Merchant M, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. Does Switching to Proliferation Signal Inhibitors Decrease the Risk of Developing Subsequent Malignancies in Heart Transplant Patients? J Investig Med. 2015; 63(1):139-140 684. Wong D, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. Do Abnormal Regadenoson Scans Predict Subsequent Poor Outcome? J Investig Med. 2015; 63(1):140 685. Yabuno J, Luu M, Liou F, Hamilton M, Kobashigawa J. Patients with Autoimmune Disease: Not a Contraindication for Heart Transplantation. J Investig Med. 2015; 63(1):141 686. Arman D, Liou F, Siddiqui S, Hamilton M, Kobashigawa J. Do Prior Driveline Infections Increase the Risk of Infection in Heart Transplant Patients Treated with ATG Induction Therapy? J Investig Med. 2015; 63(1):206 687. Liou F, Shiozaki R, Siddiqui S, Hamilton M, Kobashigawa J. HLA Antibody Class Affects Outcomes after Heart Transplant. J Investig Med. 2015; 63(1):207 688. Murayama K, Liou F, Yabuno J, Hamilton M, Kobashigawa J. Shorter Cold Ischemic Time in Older Donors Post-Heart Transplant Appears to be Protective. J Investig Med. 2015; 63(1):207 689. Kawano J, Patel J, Kittleson M, Liou F, Wong D, Jamero G, Azarbal B, Chang DH, Czer L, Trento A, Kobashigawa J. Rubidium Positron Emission Tomography and Coronary Flow Reserve Predicts Graft Function after Heart Transplant. J Heart Lung Transplant. 2015; 34(4):S48-S49 690. Kawano J, Kittleson M, Patel J, Azarbal B, Liou F, Siddiqui S, Wong D, Chang DH, Ramzy D, Czer L, Kobashigawa J. Do Abnormal Regadenoson Scans Predict Subsequent Poor Outcome? J Heart Lung Transplant. 2015; 34(4): S49 691. Kobashigawa J, Kittleson M, Liou F, Shiozaki R, Siddiqui S, Piponniau L, Geft D, Hamilton M, Czer L, Reinsmoen, Patel J. The Time Course of Development of Anti-HLA Antibodies Following Heart Transplantation. J Heart Lung Transplant. 2015; In Press 692. Patel J, Reinsmoen N, Kittleson M, Dilibero D, Liou F, Chang DH, Hamilton M, Czer L, Esmailian, Kobashigawa J. Plasmapheresis and Bortezomib for Sensitized Patients Awaiting Heart Transplantation – Worth the Effort? J Heart Lung Transplant. 2015; 34(4): S30-S31 693. Patel J, Dilibero D, Kittleson M, Sana S, Liou F, Chang DH, Hage A, Czer L, Trento A, Reinsmoen N, Kobashigawa J. Terminal Complement Inhibition for Complement Inhibition for Highly Sensitized Patients Undergoing Heart Transplantation – Doable? J Heart Lung Transplant. 2015; 34(4):S31 96 CURRICULUM VITAE JON KOB ASHIGAWA, MD 694. Esmailian F, Patel J, Kittleson M, Kao T, Liou F, Siddiqui S, Azarbal B, Chang DH, Czer L, Trento A, Kobashigawa J. Shorter Cold Ischemic Time in Older Donors Post-Heart Transplant Appears to be Protective. J Heart Lung Transplant. 2015; 34(4):S17 695. Cheng R, Azarbal B, Herr J, Ramzy D, Kobashigawa J, Arabia F, Moriguchi F. Early Crossover from Extracorporeal Membrane Oxygenation to More Durable Mechanical Circulatory Support Increases Survival to Transplant or Recovery. J Heart Lung Transplant. 2015; 34(4):S1-S368 696. Coleman B, Guo X, Patel J, Reinsmoen N, Jia Y, Kobashigawa J. Genetic Risk Score (GRS) Predicts Worse Survival in African American Heart Transplant. J Heart Lung Transplant. 2015; 34(4):S114-S115 697. Arabia F, Kittleson M, Czer L, Hajj J, Passano E, Liou F, Siddiqui S, Chang DH, Kobashigawa J, Moriguchi J. The Risk of Hospital Readmissions Following Mechanical Circulatory Support Placement. J Heart Lung Transplant. 2015; 34(4):S126 698. Patel J, Vescio R, Kittleson M, Siddiqui S, Liou F, Yabuno J, Piponniau L, Kearney B, Hamilton M, Czer L, Kobashigawa J. Single Center Experience with Amyloid Patients in the Current Era of Disease Specific Medications. J Heart Lung Transplant. 2015; 34(4):S148 699. Kittleson M, Patel J, Liou F, Siddiqui S, Chang DH, Hage A, Hamilton M, Czer L, Trento A, Esmailian F, Kobashigawa J. Combined Kidney Transplant in Patients Needing Redo Heart Transplant: Viable Option? J Heart Lung Transplant. 2015; 34(4):S187 700. Kittleson M, Patel J, Liou F, Siddiqui, Yabuno J, Chang DH, Ramzy D, Czer L, Esmailian F, Reinsmoen N, Kobashigawa J. Low Level Donor Specific Antibodies at Transplant does not Appear to be Associated with the Development of Cardiac Allograft Vasculopathy after Heart Transplantation. J Heart Lung Transplant. 2015; 34(4):S286-287 701. Siddiqui S, Kittleson M, Patel J, Liou F, Aintablian T, Chang DH, Hage A, Czer L, Esmailian F, Kobashigawa J. Risk Factors for Hospital Admissions for Rejection Following Heart Transplantation: The Real Story. J Heart Lung Transplant. 2015; 34(4):S299-S300 702. Runyan C, Arabia F, Czer L, Kittleson M, Passano E, Liou F, Yabuno J, Henry H, Chang DH, Kobashigawa J, Moriguchi J. Left Ventricular Assist Devices vs. Total Artificial Hearts: Which Causes More Cerebrovascular Accidents. J Heart Lung Transplant. 2015; 34(4):S213 703. Ghafourian K, Moriguchi J, Kittleson, Czer L, Passano E, Liou F, Huie N, Chang DH, Trento A, Arabia F, Kobashigawa J. Drop in Estimated Glomerular Filtration Rate at 1 Year after Heart Transplantation – Concern for Poor Outcome. J Heart Lung Transplant. 2015; 34(4):S92 704. Rush J, Kittleson M, Patel J, Stimpson E, Kao T, Liou F, Aintablian, Siddiqui S, Chang DH, Czer L, Esmailian F, Kobashigawa J. Is There a Risk of Cocaine and Methamphetamine Use in Heart Donors? J Heart Lung Transplant. 2015; 34(4):S213 705. Runyan C, Moriguchi J, Kittleson M, Czer L, Passano E, Liou F, Chang DH, Ramzy, Esmailian F, Kobashigawa J, Arabia F. Reliability of the Freedom Driver after Total Artificial Heart Implantation. J Heart Lung Transplant. 2015; 34(4):S276–S277 706. Stimpson, Kao T, Kim L, Morrison S, Patel J, Kittleson M, Liou F, Siddiqui S, Yabuno J, Czer L, Kobashigawa J. Care after Heart Transplant, No One Better Than Family: Wrong. J Heart Lung Transplant. 2015; 34(4):S236 707. Henry H, Arabia F, Kittleson M, Czer L, Passano E, Yabuno J, Siddiqui S, Antifantis E, Chang DH, Kobashigawa J, Moriguchi J. Does the Specific Type of Caregiver Impact Readmission after Mechanical Circulatory Support Device Placement? J Heart Lung Transplant. 2015; 34(4):S230 708. McMenamy M, Arabia F, Czer L, Kittleson M, Passano E, Liou F, Yabuno J, Chang DH, Esmailian F, Kobashigawa J, Moriguchi J. Breaking the Myth of Obesity as a Contraindication to Continuous Flow Left Ventricular Assist Devices. J Heart Lung Transplant. 2015; 34(4):S193 97 CURRICULUM VITAE JON KOB ASHIGAWA, MD 709. Ghafourian K, Patel J, Kittleson M, Passano E, Liou F, Siddiqui S, Yabuno J, Geft D, Chang DH, Czer L, Trento A, Kobashigawa J. Does Time on Ventricular Assist Device Compromise PostTransplant Outcome? J Heart Lung Transplant. 2015; 34(4):S178-179 710. Arabia F, Czer L, Kittleson M, Passano E, Yabuno J, Liou F, Siddiqui S, Chang DH, Ramzy D, Kobashigawa J, Moriguchi J. Does Gender Make a Difference after Total Artificial Heart Implantation? J Heart Lung Transplant. 2015; 34(4):S219-S220 711. Kumar P, Liou F, Patel J, Czer L, Kobashigawa J, Luthringer D. Recurrence of Amyloid in Endomyocardial Biopsies Following Orthotropic Heart Transplantation. J Heart Lung Transplant. 2015; In Press 712. Liou F, Kittleson M, Patel J, Siddiqui S, Luu M, Kearney B, Ramzy D, Chang DH, Czer L, Reinsmoen N, Kobashigawa J. Anti-Human Leukocyte Antigen Antibody Class Affects Outcomes after Heart Transplant. J Heart Lung Transplant. 2015; 34(4):S298–S299 713. Cheng R, Azarbal B, Esmailian F, Trento A, Kobashigawa J, Arabia F, Moriguchi J. Initial Implant of Ventricular Assist Devices in INTERMACS Profiles 1 and 2 Patients in Refractory Cardiogenic Shock Improves Survival to Transplant Recovery. J Heart Lung Transplant. 2015; 34(4) 714. Cheng R, Vanichsarn C, Azarbal B, Czer L, Kittleson M, Patel J, Kobashigawa J. Rapid Progression of Allograft Coronary Artery Stenosis is Decreased in Patients Who Received Antithymocyte Globulin Induction at the Time of Transplant. J Heart Lung Transplant. 2015; 34(4):S290 715. Koomalsingh K, Kiankhooy A, Ramzy D, Esmailian F, Trento A, Moriguchi J, Kobashigawa J, Arabia F. The Total Artificial Heart (TAH) Experience at Cedars Sinai Medical Center. J Heart Lung Transplant. 2015; In Press 716. Arabia F, L Czer, Kittleson M, Passano E, Liou F, Yabuno J, Henry H, Chang DH, Esmailian, Kobashigawa J, Moriguchi J. The Selection Process for the Total Artificial Heart. Am J Transplant. 2015; In Press 717. Patel J, Vescio R, Kittleson M, Siddiqui S, Liou F, Yabuno J, Piponniau L, Kearney B, Hamilton M, Czer L, Kobashigawa J. Heart Transplant for Amyloid Patients in the Current Era of Bortezomib. Am J Transplant. 2015; In Press 718. Velleca A, Kittleson M, Perry N, Patel J, Liou F, Siddiqui S, Rush J, Ramzy D, Czer L, Chang DH, Kobashigawa J. Increased Length of Stay after Heart Transplant: What are the Risk Factors? Am J Transplant. 2015; In Press 719. Kobashigawa J, Kittleson M, Patel P, Liou F, Siddiqui S, Chang DH, Azarbal B, Ramzy D, Czer L, Patel J. Outcome of Renal Sparing Protocol in a Cross-Sectional Analysis after Heart Transplant. Am J Transplant. 2015; In Press 720. Stimpson E, Kao T, Kim L, Morrison S, Patel J, Kittleson M, Liou F, Siddiqui S, Yabuno J, Czer L, Kobashigawa J. Social Support after Heart Transplant. Am J Transplant. 2015; In Press 721. Kawano J, Kittleson M, Patel J, Azarbal B, Liou F, Siddiqui S, Wong D, Chang DH, Ramzy L, Czer L, Kobashigawa J. Predictive Value of Regadenoson Scans after Heart Transplant. Am J Transplant. 2015; In Press 722. Kobashigawa J, Kittleson M, Liou F, Shiozaki R, Siddiqui S, Piponniau L, Geft D, Hamilton M, Czer L, Reinsmoen N, Patel J. Natural History of Anti-Human Leukocyte Antigen Antibodies after Heart Transplant. Am J Transplant. 2015; In Press 723. Patel J, Reinsmoen N, Kittleson M, Dilibero D, Liou F, Chang DH, Hamilton M, Czer L, Esmailian, Kobashigawa J. Outcome of Bortezomib/Plasmaperesis for the Sensitized Patient Awaiting Heart Transplant. Am J Transplant. 2015; In Press 724. Kobashigawa J. The Changing Face of First-Year Intravascular Ultrasonography in Heart Transplantation. 98 CURRICULUM VITAE JON KOB ASHIGAWA, MD 725. Patel J, Reinsmoen N, Kittleson M, Velleca A, Dilibero D, Liou F, Chang DH, Hage A, Czer L, Esmailian F, Kobashigawa J. Rituximab with Intravenous Immune Globulin in Sensitized Patients Awaiting Heart Transplant: Does it Work? Am J Transplant. 2015; In Press 726. Jamero G, Moriguchi J, Czer L, Kittleson M, Siddiqui S, Liou F, Arman D, Lam L, Chang DH, Zakowski P, Kobashigawa J, Arabia F. Anti-Thymocyte Globulin Induction in Infected Mechanical Circulatory Support Patients: Is it Safe? Am J Transplant. 2015; In Press 727. Arabia F, Kittleson M, Czer L, Hajj J, Passano E, Liou F, Siddiqui S, Chang DH, Kobashigawa J, Moriguchi J. Assessment of Hospital Readmissions after Mechanical Circulatory Support. Am J Transplant. 2015; In Press 728. Henry H, Arabia F, Kittleson M, Czer L, Passano E, Yabuno J, Siddiqui, Antifantis E, Chang DH, Kobashigawa J. Type of Caregiver and Outcome after Mechanical Circulatory Support Placement. Am J Transplant. 2015; In Press 729. Luu M, Kittleson M, Patel J, Liou F, Siddiqui S, Pipponiau L, Hage A, Chang DH, Czer L, Trento A, Kobashigawa J. T-Cell Immune Function vs. Gene Expression Profiling for Heart Transplant Rejection. Am J Transplant. 2015; In Press 730. Kittleson M, Patel J, Liou F, Siddiqui S, Fong A, Johnson M, Chang DH, Czer L, Esmailian F, Reinsmoen N, Kobashigawa J. The Effects of Donor Specific Anti-Human Leukocyte Antigen Antibodies Late after Heart Transplantation. Am J Transplant. 2015; In Press 731. Kittleson M, Patel J, Liou F, Siddiqui S, Yabuno J, Chang DH, Ramzy D, Czer L, Esmailian F, Reinsmoen N, Kobashigawa J. Is There a Protective Value for Low Level Donor Specific Antibodies to Prevent Cardiac Allograft Vasculopathy after Heart Transplant? Am J Transplant. 2015; In Press 732. Kobashigawa J, Ghafourian K. Slowing Sinus tachycardia in Heart Transplant Recipients: Is It Time? Revista Espanola de Cardiologa. 2015; In Press. 733. Chang DH, Kobashigawa J. Novel Diagnostic and Treatment Strategies for Allograft Vasculopathy. Expert Rev Cardiovasc Ther. 2015; In Press. 734. Cole, RM, Kobashigawa J. Desensitization Strategies Pre-and Post-Cardiac Transplantation. Current Treatment Options in Cardiovascular Medicine. 2015; In Press. 735. Kobashigawa J. The Changing Face of First-Year Intravascular Ultrasonography in Heart Transplantation. JACC: Heart Failure. 2015; In Press M E N TO R I N G Summer Research Interns (Undergraduate Students) Description: Retrospective research projects are developed and assigned to undergraduate student interns. Responsibilities for interns include conducting literature searches and drafting data collection tools; collecting demographic and medical information from medical records; entering and managing data in project spreadsheets; assisting in preparation of results in the form of abstracts and manuscripts; participating in weekly research meetings; completing training in the protection of human subjects; adhering to HIPAA requirements. All student interns have the opportunity to submit a research abstract for publication and presentation. Pamela Alameda, University of California Los Angeles Tamar Aintablian, University of California, Irvine Ani Aharonyan, University of California Los Angeles 99 CURRICULUM VITAE JON KOB ASHIGAWA, MD Allison Ankrom, University of Washington Nima Assad, University of California San Diego Olivia Barry, University of California Berkeley Ashland Brown, University of California Los Angeles Erica Brownfield, University of California Los Angeles Will Brubaker, Brigham Young University Kristin Bucher, University of California Santa Cruz Stephanie Carr, University of California Los Angeles Judith Cassem, University of California Los Angeles Jennifer Chuang, University of California Los Angeles Greg Cogert, University of California Los Angeles Justin Davidoff, University of California Los Angeles Stephanie Davis, University of California Los Angeles Jeffrey Dyo, University of California San Diego Kim Einhorn, University of California Los Angeles Julie English, University of California Los Angeles Albert Geskin, University of California Los Angeles Sheryllene Go, University of California Los Angeles Lakshmi Gokanapudy, University of California Los Angeles Zachary Goldstein, University of Califon Los Angeles Jordan Kawano, CA State Polytechnic University, Pomona Matt Kawano, University of California Davis Francine Kim, University of Notre Dame Ye Seul Kim, University of California Los Angeles Krista Kiyosaki, Stanford University Erin Kobashigawa, Stanford University Brian Kobashigawa, University of Michigan Laura Kobashigawa, Brown University Paul Lee, University of California Los Angeles Bobby Lee, University of California Los Angeles Frances Lee, Emory University Allen Lipson, University of California Los Angeles Peter Lin, University of California Los Angeles Gaia Magnani, University of California Los Angeles Tatiana Manayan, Sacramento State University Asha Mansukhani, University of California Los Angeles Angela Marquez, University of California Los Angeles Sam Mayne, University of California Berkeley Madeleine Merchant, Carelon College Allison Merz, Amherst College Shaun Miller, University of California Los Angeles Ariel Moradzadeh, University of California Los Angeles Nathan Moradzadeh, University of California Los Angeles Kellee Murayama, Occidental College Nicholette Murray-Bruce, University of Southern California Jonathan Nakashima, University of California, Los Angeles Alex Ngan, Columbia University Jay Patel, Drexel University Dhruv Patel, University of California Los Angeles Nishil Patel, University of California Los Angeles Pareena Patel, University of Warwick Mai Phan, University of California Los Angeles Monica Plesa, University of California Los Angeles Matthew Rafiei, University of California Los Angeles Thomas Ro, University of California Los Angeles Alex Sabad, University of California Los Angeles Sarmen Sarkissian, University of California Los Angeles Andrea Seid, University of California Los Angeles Rayshma Sharoff, University of California Los Angeles Jeremy Shaw, University of Texas Southwestern Brian Shiozaki, University of Southern California Ryan Shiozaki, University of California, Los Angeles 100 CURRICULUM VITAE JON KOB ASHIGAWA, MD Michelle Siu, Loyola Marymount University Helen Song, University of California Los Angeles Lily Stern, University of California Los Angeles Eric Sue, Stanford University Joy Tang, Washington University Mia Tittle, University of California Santa Barbara Ajay Vaidya, University of Oklahoma Lianne Wener, University of California Los Angeles Derek Wong, University of California Los Angeles Samantha Wong, University of California Los Angeles Grace Wu, Stanford University Jamie Yabuno, University of California Los Angeles Meghana Yajnik, University of California Los Angeles Research Mentor (Medical School Students) Description: Medical School students are mentored through the research process, including developing concepts, refining lines of inquiry, literature review, data collection and analysis and abstract submission. Research mentoring is supplemented by clinical exposures. Aaron Fong, Baylor College of Medicine, 2017 Darian Arman, Tulane University School of Medicine, 2017 Amanda Aquino, Michigan State University College of Human Medicine, 2016 Alexander Chehrazi-Raffle, Chicago Medical School, 2016 Anup Parikh, University of Medicine and Dentistry of New Jersey, 2016 Brandon Cohen, NYU School of Medicine, 2015 David Lee, University of Nevada Medical School, 2011 Michael Share, Jefferson Medical College, 2010 Eric Sue, USC Medical School, 2010 Keira Lo, Taiwan, 2008-2009 Ohnmar Aye, Taiwan, 2006-2007 Boris Arbit, Dartmouth College Medical School, 2006 Anne Silao, MD - University of the East, Philippines, 2005-2006 Sumeet Subherwal, UC Irvine Medical School, 2002-2003 Greg Cogert, UC Irvine Medical School, 1996-1999 Kengo Soghoyan, UCD School of Medicine, 2018 Evan Norris, George Washington University Medical School, 2018 Clinical Research Mentor (Interns, Residents, Fellows) Description: Junior investigators/Junior Faculty are mentored through the investigative research process, including developing and implementing protocols, data collection and analysis, abstract submission and presentation at major scientific forums and manuscript writing and publication. Deborah Budge, UCLA Cardiology Fellow Wanxing Chai, Peking Union Medical College David Chang, UCLA Cardiology Fellow Daniel Cruz, UCLA Cardiology Fellow Sandesh Dev, UCLA Heart Transplant Fellow Howard Dinh, UCLA Cardiology Fellow Hiroshi Furukawa, UCLA Research Fellow Pavel Goyhkman, Cedars-Sinai Cardiology Fellow Aric Gregson, UCLA Infectious Disease Reema Hasan, University of Michigan Eric Hong, UCLA Intern Helen Huang, Cedars-Sinai Resident Brandon Itagaki, UCLA Resident Aarya Kafi, Cedars-Sinai Resident Brandon Kai, Cedars-Sinai Resident 101 CURRICULUM VITAE JON KOB ASHIGAWA, MD Tigran Khachatryan, Cedars-Sinai Resident Pranav Kansara, Cedars-Sinai Cardiology Fellow Brian Kim, UCLA Intern Adva Kornblit, Cedars-Sinai Resident Evan Kransdorf, Cedars-Sinai Cardiology Fellow Ryan Morrissey, Cedars-Sinai Cardiology Fellow Amish Parikh, UCLA Resident Vishal Parikh, Cedars-Sinai Resident David Perkel, Cedars-Sinai Resident Tim Provias, UCLA Intern/Resident Stuart Russell, UCLA Cardiology Fellow Esha Sachdev, Cedars-Sinai Resident Yuji Saito, UC Irvine Cardiology Fellow Esther Shao, UCLA Cardiology Fellow Timothy Smith, UCLA Resident Stephanie Smooke, UCLA Resident Sahar, Sohrabian, UCLA Resident Eric Sue, Cedars-Sinai Resident Rigveg Tadwalker, Cedars-Sinai Resident Vijay Vaidya, UCLA Resident Christopher Vanichsarn, Cedars-Sinai Resident Karolina Juszczynski, Western Town College Clinical Preceptorships (1 – 4 Week Training): Description: Clinical training in heart failure, heart transplantation and mechanical circulatory support, designed to address the specific needs of visiting faculty and include observational training, didactic lectures, and case studies. Simon Jackson, MD - Queen Elizabeth II Hospital, Halifax, October 2003 Marie Helene Le Blanc, MD - University of Laval, October 2003 Vivek Rao, MD - Toronto General Hospital, October 2003 Alan Menkis, MD - London Health Sciences Center, October 2003 Chih-Hsin Hsu. MD - National Cheng Kung University, September 2005 Waqas Ghumman, MD – Indiana University, October 2008 Tomako Kato, MD – National Cardiovascular Center, Japan, February 2008 Matsuyama, MD – National Cardiovascular Center, Japan, February 2008 Masanobu Yanase, MD – National Cardiovascular Center, Japan, February 2010 Tomoyuki Fujita, MD – National Cardiovascular Center, Japan, February 2010 Michael Dickinson, MD – Spectrum Health, Michigan, November 2011 Osamu Seguchi, MD – National Cardiovascular Center, Japan, March 2011, February 2014 Yoshihiro Murata, MD – National Cardiovascular Center, Japan, March 2011 Yuk “Fai” Lai, MD - ?? August 2012 Lilian Grigorian, MD – University Hospital Complex of Vigo, August 2013 Byung-Chul Chang – Yonsen Medical Center, Seoul, Korea, February 2014 M U LT I - CE N T E R S T U D I E S RS61443 (Syntex, study 1866) for refractory cardiac allograft rejection, 1991-92, UCLA Principal Investigator. Multicenter intravascular ultrasound study in cardiac transplant patients to define the natural progression of transplant coronary disease, (CVIS, Inc) 1993-present, UCLA Principal Investigator. Chairman, Executive Steering Committee, for the Multicenter Mycophenolate Mofetil Randomized Primary Prevention Trial in Cardiac Transplant Patients (Roche, study 1864), 1995-1999. 102 CURRICULUM VITAE JON KOB ASHIGAWA, MD Mycophenolate Mofetil (Roche, study 1864) randomized primary prevention trial in cardiac transplant patients, 1994-1999, UCLA Principal Investigator. Intravascular ultrasound core laboratory for Mycophenolate Mofetil Study (Roche, study 1864) 1994-1999, Study Co-Principal Investigator. Rapamycin (Wyeth Laboratories) randomized study for the treatment of ISHLT grade 2 or 3A rejection in cardiac transplant patients, 1994-present, UCLA Principal Investigator. Sandoz multicenter study for the use of cyclosporine in cardiac transplantation. 1994-present, UCLA Principal Investigator. RAD (Novartis) randomized trial in primary heart transplant patients, 1998-2007, UCLA Principal Investigator. Zenapax (Roche) randomized trial in primary heart transplant patients, 1998-2005, UCLA Principal Investigator and member of Steering Committee of this Multicenter Study. Quality of Life Outcomes for Heart Transplant Patients 5-10 years After Transplantation (NIH), 2000present, UCLA Principal Investigator. Breath Test randomized trial in primary heart transplant patients, 2000-present, UCLA Principal Investigator. Valganciclovir and Cardiac Allograft Vasculopathy (VCAV) Multicenter Study, 2001-present, UCLA Principal Investigator and member of Steering Committee of this Multicenter Study. A 12-month, Single-blind, Randomized, Parallel Group, Multicenter Study to Investigate the Efficacy and Safety of ERL080A Compared with MMF in de novo Heart Recipients (Novartis), 2001-2007, UCLA Principal Investigator and member of Steering Committee. Multicenter Study of Tacrolimus/MMF vs. Cyclosporine/MMF vs. Tacrolimus/Sirolimus (3-arm, Fujisawa), 2001-2005, UCLA Principal Investigator and member of the Steering Committee. A Retrospective Analysis of Cardiovascular and Immunologic Risk Factors Affecting Survival of De Novo Cardiac Transplant Recipients (Fujisawa), 2002-2003, Principal Investigator. Non-Invasive Detection of Rejection in Cardiac Allograft Recipients Using Gene Expression Profiling: CARGO Trial 2002-2007, UCLA Principal Investigator and member of the Steering Committee. Intravascular Ultrasound (IVUS) Validation Study Among Heart Transplant Recipients: Outcomes After 5 Years (Novartis), 2002-2005, Principal Investigator. Intravascular Ultrasound (IVUS) Studies among Heart Transplant Recipients Participating in the Mycophenolate Mofetil Study: Let’s Take Another Look (Roche), 2003-2007, Principal Investigator. Randomized trial monitoring acute rejection by surveillance biopsy, compared to peripheral blood leukocyte gene profiling, 2004, Endpoint Committee Member. A Facilitated Access Program to Provide Everolimus (RAD) for Maintenance Patients Completing Therapy in RAD Trials in Solid Organ Transplantation (RAD 2401, Novartis), 2004-present, UCLA Principal Investigator. A comparison between tacrolimus and cyclosporine in de novo cardiac transplant recipients (FKC-009, Astellas), 2005-present, UCLA Principal Investigator. Ultrafiltration versus IV Diuretics for Patients Hospitalized for Acute Decompensated Congestive Heart Failure: A Prospective Randomized Clinical Trial (UNLOAD, CHF Solutions), 2005-2006, Co-Investigator. Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF, Medtronic), 2006-present, Co-Investigator. 103 CURRICULUM VITAE JON KOB ASHIGAWA, MD A 24 month, multi-center study Certican with reduced Neoral vs. MMF with standard dose Neoral in de novo heart transplant recipients (RAD 2310, Novartis), 2006-present, UCLA Principal Investigator, Steering Committee. Ability of the PD2i cardiac analyzer to predict the risk of high risk patients developing ventricular fibrillation or ventricular tachycardia (VITAL, Vicor), 2007-present, Co-Investigator. Observational Study of Alloimmunity in Cardiac Transplant Recipieints (CTOT-05, NIAID/NHLBI), 2008-present, UCLA Principal Investigator. Early Invasive Monitoring Attenuation Through Gene Expression Trial (EIMAGE, XDx, Inc.), 2009, UCLA Principal Investigator. CTOT 13 -Sensitization Trial (NIAID/NHLBI/NIH), Protocol Chair (2009 – present) Chairmain, Steering Committee 104 November 29, 2015 AST Nominating Committee, It is a distinct pleasure to recommend Jon Kobashigawa for the AST’s Senior Achievement Award in Clinical Transplantation. I am not sure it is possible to overstate the key role Jon has played in the advancement in the field cardiac transplantation over the past 30 years. Jon is internationally acclaimed for his work and has led much of the seminal research in the field of cardiac transplantation including the effect of statins on coronary vasculopathy, the quantification of vasculopathy and subsequent risk prediction with intravascular ultrasound, the use of mycophenolate mofetil, daclizumab and everolimus in heart transplantation, desensitization therapy, treatments for antibody medicated rejection and molecular diagnostics for the assessment of the risk of rejection. Jon has hundreds of impactful publications in every major journal, including many first author publications in the New England Journal of Medicine. With his world renowned expertise and collaborative spirit he has served in innumerable roles in every society related to cardiac transplantation, including many prominent leadership positions within the AST including both the ATC and WTC Program Committees, the Clinical Practice Committee, Practice Guidelines Committee and currently as co-chair of the Thoracic and Critical Care COP. Jon’s organizational prowess and desire to improve the field has resulted a long history of organizing the cardiac transplant community to address knowledge gaps, discuss controversies and develop novel treatment strategies. The most recent example of which was the Consensus Conference on Donor Heart Selection and Management prior to the 2015 ATC. Jon’s impact has been felt throughout the field of cardiac transplantation with his roles on editorial boards, as a reviewer for dozens of journals, his hundreds of presentations both nationally and internationally, innumerable abstract presentations and over 30 book chapters. Jon has not only been productive and collaborative, but he is a thought leader, if not the thought leader, in the field of cardiac transplantation. Much of the basis of what is now considered routine clinical care after cardiac transplantation was established by Jon’s work. He is constantly ahead of the curve and continues to push the field forward through his keen clinical acumen and his unmatched vision. While he has shaped the field of cardiac transplantation through his dedication, research, and collaboration, he also has an unparalleled record of mentorship of the next generation of transplant physicians. Jon has nearly 4 pages of students, interns, residents, fellows and visiting faculty which he has mentored, many of whom have gone on to become leaders in transplantation. His colleagues also recognize Jon for his affability, approachability and unmatched effort and enthusiasm for patients and the field. Jon is truly remarkable and it is difficult to adequately quantify his impact on cardiac transplantation. He is universally recognized as a leader in research, clinical care and mentorship whose impressive body of work has become the basis for the care of patients and whose energy and forwarding thinking approach will continue to advance the field. I cannot think of a practicing physician in the field of cardiac transplantation who is more deserving and emblematic of the AST’s Senior Achievement Award in Clinical Transplantation. Sincerely, Jeffrey Teuteberg, MD