Download Proton Therapy for Gastrointestinal Cancer

Mouth
Oesophagus
(Food pipe)
Windpipe
(trachea)
Lungs
Stomach
In planning proton beam treatment to the
oesophagus it is clear that future breathing
complications are prevented because
protons do not interfere with lung tissue or
the spinal cord.
COMPARED TO CONVENTIONAL RADIOTHERAPY
PROTON THERAPY IS LESS TOXIC
The goal of radiotherapy is to eradicate cancer cells while
sparing healthy tissue. Conventional radiotherapy goes
straight through the whole body, does not stop in the tumour, and damages healthy tissue before and behind the tumour. There are many sensitive tissues such as in the digestive tract, small intestine, liver, kidney, lungs, mediastinum
and the heart as well. The risk of damage to healthy tissue
limits the amount of radiation that can be given, and this
reduces the effectiveness of treatment. Conventional X-ray
radiotherapy cannot achieve final dosages high enough to
always destroy the tumour, or does so only with a high risk
of causing permanent health complications.
Advanced cancer treatments,
state-of-the art examinations and an
individualised approach. The Proton
Therapy Center in Prague is more than
just a hospital.
Proton Therapy Center Czech s.r.o.
Budínova 2437/1A, Prague 8, 180 00
Appointments: +420 222 999 000
GPS: 50.1171363, 14.4646944
E-mail: [email protected]
WIFI Available
More information: en.ptc.cz
Proton Therapy UK Ltd.
www.ukprotontherapy.co.uk
Proton Therapy Hungary
www.protonterapia.hu
Proton Therapy Germany
www.krebsprotontherapie.de
Proton Therapy Spain
www.protoncenter.es
Dose distribution comparison for treatment of the pancreas
(conventional radiotherapy vs. proton radiotherapy)
In contrast to conventional radiotherapy, a proton beam
can be stopped at any point in the tumour with millimetre
accuracy where it is needed. Proton radiation precisely
targets the tumour and other tissues that may need treatment (such as lymph nodes in the mediastinum) while
surrounding healthy tissue receives only 20-30% of radiation. When treating pancreatic cancer for example, protons reduce the dose to the spinal cord by about 78%, the
liver by about 55% and the kidneys down to 23%.
Proton Therapy Russia
http://ru.ptc.cz/
Proton Therapy France
www.cancertraitement.fr
Proton Therapy Türkiye
www.protontedavisi.com.tr
Proton Therapy for
Gastrointestinal Cancer
A new chance to treat
pancreatic carcinoma, liver
carcinoma and oesophageal
carcinoma
Proton therapy is a completely new and
revolutionary cancer treatment for the
pancreas, liver and esophagus.
How is cancer of the pancreas, cancer of
the esophagus, and primary liver cancer
treated?
In the past there was virtually no effective treatment option
for pancreas, liver and oesophagus cancer. Despite all the
methods currently available cure rates were low, and only
slowed disease progression. In over half of patients who
receive post-operative chemotherapy, the cancer returns.
With conventional radiotherapy there is always damage to
surrounding organs – like the adjacent small intestine, liver
and kidney, and therefore conventional radiotherapy is indicated less and less.
Please be aware that:
The characteristics of proton radiation are a three-dimensional dose distribution with the highest level of precision
and conformity to the tumour. This means less normal tissue
is irradiated, causing less toxicity and higher doses to the
tumour, thereby increasing the possibility of a cure. It is far
more appropriate to use proton therapy for the treatment of
tumours close to or in vital structures, including tumours
of the gastrointestinal tract, such as cancer of the pancreas,
liver or oesophagus.
Proton therapy allows us to
achieve what could not previously
be achieved with conventional
radiation therapy, and opens
the door to successfully treating
complex diagnoses, such as
pancreatic cancer.
Dr. Pavel Vítek, Ph.D., MBA
Radiation Oncologist,
Proton Therapy Center Czech.
International research indicates that
proton therapy offers new treatment
possibilities for numerous complicated
diagnoses.
Preoperative irradiation of pancreatic cancer can enable
surgery to be performed, or improves the results of surgery
itself. Separate irradiation achieves tumour suppression,
life extension and relief from troubles. Proton therapy offers
new possibilities by preserving sensitive healthy tissues
around the pancreas like the small bowel, liver, kidney and
spinal cord. Proton therapy has only minimal side effects
with better final outcomes.
Tumours of the oesophagus need surgical removal post-treatment. Sometimes an operation cannot be performed and
irradiation is applied seperately, as with locally advanced
tumours. With conventional radiotherapy it is impossible
to apply a high enough dose to destroy the tumour without
causing serious side effects like vomiting, weight loss, pain
and decreased food intake.
Liver tumours or metastases in the liver need high doses of
radiation to be destroyed, and healthy liver tissue cannot
tolerate this. Thus only a low radiation dose can be applied,
and this dose is insufficient to completely destroy the tumour. Alternatively, a proton beam can preserve healthy
tissue and destroy the tumour with high dosages.
Unlike conventional radiotherapy, proton
therapy for pancreatic cancer:
• r educes radiation exposure to the spinal cord by 78%
• r educes radiation exposure to the liver by 55%
• r educes unnecessary radiation exposure to the kidney by
23%
The pancreas and kidneys - essential organs for life...
50 %
27 %
% of radiation to kidneys
Proton therapy 27 %
Conventional radiotherapy 50 %
In 70% of cases pancreatic cancer is
diagnosed too late. In addition to cancer
treatments, the Proton Therapy Center
provides complete diagnostic services.
PROTON THERAPY IS SUITABLE FOR: Tumours of the pancreas
• Preoperative radiotherapy for locally advanced operable tumours
• Primary radiotherapy, or in combination with chemotherapy, for locally advanced inoperable tumours
• Postoperative radiotherapy after complete or partial resection of the pancreas
Oesophageal tumours
• Preoperative radiotherapy for locally advanced operable tumours
• Primary radiotherapy, or in combination with chemotherapy, for locally advanced inoperable tumours
Hepatocellular (liver) carcinoma
• Liver tumours unsuitable for surgery without extrahepatic involvement
DURING TREATMENT:
Proton treatment is performed on an outpatient basis.
Treatment time takes from about 3 to 6 weeks, depending
on the stage of the disease. Each visit takes 45 minutes,
but beam delivery only takes a few minutes.
Before and during treatment, the qualified patient management team arranges accommodation and all other support services during your stay in Prague.
In addition to this PTC offers complete diagnostics and
proton beam therapy for cancer under one roof.