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Variations and Control of
Cellular Respiration
Figure 9.16
Electron shuttles
span membrane
2 NADH
Glycolysis
2 Pyruvate
Glucose
MITOCHONDRION
2 NADH
or
2 FADH2
2 NADH
Pyruvate oxidation
2 Acetyl CoA
 2 ATP
Maximum per glucose:
CYTOSOL
6 NADH
2 FADH2
Citric
acid
cycle
Oxidative
phosphorylation:
electron transport
and
chemiosmosis
 2 ATP
 about 26 or 28 ATP
About
30 or 32 ATP
Figure 9.18
Glucose
CYTOSOL
Glycolysis
Pyruvate
No O2 present:
Fermentation
O2 present:
Aerobic cellular
respiration
MITOCHONDRION
Ethanol,
lactate, or
other products
Acetyl CoA
Citric
acid
cycle
Figure 9.17a
2 ADP  2 P i
Glucose
2 ATP
Glycolysis
2 Pyruvate
2 NAD 
2 Ethanol
(a) Alcohol fermentation
2 NADH
 2 H
2 CO2
2 Acetaldehyde
Figure 41.18
2 Reticulum
1 Rumen
Esophagus
Intestine
4 Abomasum
3 Omasum
Figure 9.17b
2 ADP  2 P i
Glucose
2 ATP
Glycolysis
2 NAD 
2 NADH
 2 H
2 Pyruvate
2 Lactate
(b) Lactic acid fermentation
Figure 9.19
Proteins
Carbohydrates
Amino
acids
Sugars
Glycolysis
Glucose
Glyceraldehyde 3- P
NH3
Pyruvate
Acetyl CoA
Citric
acid
cycle
Oxidative
phosphorylation
Fats
Glycerol Fatty
acids
Figure 9.20
Glucose
AMP
Glycolysis
Fructose 6-phosphate

Stimulates

Phosphofructokinase

Fructose 1,6-bisphosphate
Inhibits
Inhibits
Pyruvate
ATP
Citrate
Acetyl CoA
Citric
acid
cycle
Oxidative
phosphorylation
Figure 45.7-2
Epinephrine
Adenylyl
cyclase
G protein
G protein-coupled
receptor
GTP
ATP
cAMP
Inhibition of
glycogen synthesis
Promotion of
glycogen breakdown
Protein
kinase A
Second
messenger
Figure 41.20
Transport of
glucose into
body cells
and storage
of glucose
as glycogen
Pancreas
secretes
insulin.
Stimulus:
Blood glucose
level rises
after eating.
Homeostasis:
70–110 mg glucose/
100 mL blood
Breakdown
of glycogen
and release
of glucose
into blood
Stimulus:
Blood glucose
level drops
below set point.
Pancreas
secretes
glucagon.
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