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Essay Plan
Problem/Question：
What are the advantages and disadvantages of only using
drugs in the treatment of breast cancer?
Introduction
Drugs treatment advantages：
1.No surgery risk
2.Some radiotherapy may be replaced by drugs
3.Targeted drugs
4.Drugs can treat metastatic breast cancer
Drugs treatment disadvantages：
1.Drug resistance
2.Side effects
3.Just can be assistance after surgery
Positon:
Advantages
Reference
(PDQ,2016)
(Hematol, 2004)
Clinical treatment needs multiple therapies now
Section1:
No surgery risk
Argument: Surgery risks
(Cheng and Ueno,2011)
1.Apart from tumors ,other normal parts need to be
removed
(Cheng et al,2016)
2.Surgery may generate metastatic breast cancer
3.Someone may die during surgery
（Cheng,Jeffrey,Clymer,Nicole ,Ferko
,2016）
Counter argument:drugs can replace surgery to prevent risks
Example：chemotherapy replaces mastectomy
Argument :The problems of radiotherapy
(Diehn and F.Clarke,2006)
Section2：
Some radiotherapy may 1.Radiotherapy has side effects
be replaced by drugs
(Reya,Morriso and Clarke,2001)
2.Some tumor is radioresistant：
A. Illustrating reason why tumor has resistance
B. Example about the findings of Philips/ Bao ： (Al-Hajj,Wicha,Benito-Hemandez
Radioresistance
A,2003)
Counter argument: Some radiotherapy may be replaced by
drugs
(Khodabandehloo, Zahednasaband
Advantages：
1.Do not break normal tissues
Hafez,2016)
2. Drug Delivery to specific tumor target
Example：Lapatinib ditosylate and Nanocarriers Usage for (Nelson and Dolder,2007）
Drug Delivery
Argument: many people cannot have an operation many (Reya,Morrison,Clarke,Weissman,
Section4：
Drugs
can
treat times
2001)
metastatic breast cancer
Counter argument:using drugs cannot tolerant surgery risk
again
Section3：
Targeted drugs
Disadvantages
Section1:
Drug resistance
Section2:
Side effects
Focus population：
1. Cancer recurrence
2. Terminal cancer
Focus tissues
1.Bone
2.Brain
3.Hepatic
Transition
1. The reason why tumors have drug resistance
2. Factors influence resistance
3. Result: many drugs cannot use during a long time
Argument:drugs have side effects on breast cancer
1. Heart problems
2. Bone health
3. Arthralgias
Argument:surgery is the main method to treat cancer
Section3:
Just can be assistance
after surgery
Counter argument:Most of drugs using now are just
assistance
Example1.hormone therapy
Example2.chemotherapy
conclusion
Summarise:
1.Drugs treatment advantages and disadvantages
2.To show we cannot only use drugs to cure breast cancer
now,and we need to balance different treatments
3.To imagine maybe only using drugs can cure cancer in the
future
(Sauer,2011)
(Feng,Tiede, Massague,2007)
(Bodai,2015)
(Sadler,Pugazhendhi and Darbre，
2009）
(Velasco-Velázquez, M.A.,2012)
Liting Qiu