Download 14:50 Ulla Knaus - EU-ROS

New concepts and views in redox biology and
oxidative stress research – achievements of COST
Action BM1203 (EU-ROS)
Final meeting
Eilat, Israel, 7-10 November 2016
Monday 7 November
11:00 - 13:00 MC meeting and opening of the conference
13:00 - 14:30 Lunch
Session 1 - chair: Ulla Knaus
14:30 - 14:50 Ulla Knaus - Achievements of WG1
14:50 - 15:20 Edgar Pick - Thou shall not - The ten commandments
of NOX research
15:20 - 15:50 Ulla Knaus - Interkingdom communication via H2O2
15:50 - 16:20 Karl-Heinz Krause - The proton channel Hv1 as a key
player in NOX-dependent ROS generation
16:20 - 16:50 Kostas Tokatlidis - H2O2 signaling and oxidative
protein folding into the mitochondrial intermembrane
space
16:50 - 17:30 Coffee break
Session 2 - chair: Andreas Daiber and Fabio Di Lisa
17:30 - 18:00 Ismail Laher - Exercise relieves oxidative stress in
metabolic syndrome
18:00 - 18:30 Fernando Antunes - Quantitative information on
hydrogen peroxide signaling experiments
19:00 - 21:00 Dinner
Tuesday 8 November
Session 3 - chair: Thomas Kietzmann and Jaap Joles
08:30 - 08:50 Thomas Kietzmann - Achievements of WG2
08:50 - 09:20 Jaap Joles - Targeting multiple pathways reduces
renal and cardiac fibrosis in rats with subtotal
nephrectomy followed by coronary ligation
09:20 - 09:50 Thomas Kietzmann - ROS, liver metabolism and
cancer
09:50 - 10:20 David Young - Structure dynamics of ascorbate
regeneration
10:20 - 11:00 Coffee break
Session 4 - chair: Shlomo Sasson and Ron Kohen
11:00 - 11:30 Oren Tirosh - Bile acids therapy for obesity-related
chronic diseases
11:30 - 12:00 Shlomo Sasson - Lipohormesis in pancreatic beta cells
12:00 - 12:30 Maria Monsalve - Mitochondrial dysfunction,
inmortalization and tumor development
12:30 - 13:00 Guy Cohen - The biblical Balm of Gilead protects
human skin explants against UVB-induced damage
13:00 - 14:30 Lunch
Session 4 - chair: Manuela Garcia Lopez
14:30 - 14:50 Manuela Garcia Lopez - Achievements of WG3
14:50 - 15:20 Rafael Leon - Non-conventional target approach for
drug discovery against Alzheimer's disease: NRF2 upregulation as antioxidant as antioxidant modulator of
neuroinflammation
15:20 - 15:50 Anna-Lisa Levonen - The effect of Nrf2 and
electrophilic Nrf2 modulation on atherogenesis
15:50 - 16:20 Vincent Jaquet - NADPH oxidases as drug targets in
CNS pathologies
16:20 - 16:50 Per Wikstrom - The development of a highly selective
Nox4 inhibitor
16:50 - 17:30 Coffee break
Session 5 - chair: Jaime Kapitulnik
17:30 - 18:00 Ron Kohen - Activation of the Nrf2-keap 1 protecting
pathway by unique electrophiles: plasmonic gold
nanoparticles as an example
18:00 - 18:30 - Carla Ferreri - Membrane fatty acid remodeling and
cellular stress: the role of lipidomic monitoring
20:00 Festive dinner
Wednesday 9 November
Session 6 - chair: Yves Frapart
08:30 - 08:45 Yves Frapart - Achievements of WG5
08:45 - 09:10 Milos Mojovic - EPR spin-labeling spectroscopy as
potential biomarker technique for metabolic and
metabolic-related disorders
09:10 - 09:35 Jan Vacek - Protein interactions with methylglyoxal:
from molecular to clinical studies
09:35 - 10:00 Pavel Andjus - Superoxide dismutase G93A mutation
in ALS and its many facets
10:00 -10:20 Stefan Chlopicki - Changes in ACE/ACE-2
angiotensin profile in mice with dilated
cardiomyopathy: relationship to MRI-based
characterization of ventricle function
10:20 - 10:50 Coffee break
Session 7 - chair: Pietro Ghezzi
10:50 -11:10 Pietro Ghezzi - Achievements of WG4
11:10 -11:40 Paul Winyard - Inflammation and nitrative stress
11:40 -12:10 Serge Bottari - Biomarkers of nitro-oxidative stress
12:10 -12:40 Helen Griffiths - Lipid oxidation biomarkers
12:40 -13:10 Chryssostomos Chatgilialoglu - Radical stress in
biomimetic models for biomarker discovery
13:10 -14:40 Lunch
Session 8 - chair: Vincent Jaquet
14:40 -15:00 Vincent Jaquet - Achievements of WG6
15:00 -15:30 Andrey Y. Abramov - ROS production in the brain:
from signaling to pathology
15:30 -16:00 Isabel Lastres-Becker - Fractalkine/CX3CR1 are
essential for Nrf2-dependent microglial activation:
implications in Tauopathies
16:00 -16:30 Coffee break
16:30 -17:00 Antonio Cuadrado - The REDBRAIN Project
17:00 -17:30 Gina Manda - The NANOTHER Project
19:00 -21:00 Dinner
Thursday 10 November
Session 9 - chair: Jaime Kapitulnik
09:00 -09:20 Jaime Kapitulnik - Summary of STSM grants
09:20 -09:40 Natalia Robledinos - Redox signaling in the regulation
of adult neurogenesis
09:40 -10:00 David Novak - Cytochrome c and its heme-disrupted
analogs revealed by electrochemistry and EPR
spectroscopy
10:00 -10:20 Damir Kracun - Folic acid promotes recycling of
tetrahydrobiopterin and protects against hypoxiainduced pulmonary hypertension by recoupling
endothelial nitric oxide synthase
10:20 - 12:00 Action Chair, Vice-Chair and Core Group members ROUNDTABLE: Summary and achievements of
COST Action BM1203 (EU-ROS) and the future of
ROS research