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Warm-Up (3/31)
Notch signaling is a conserved signaling pathway
present in most eukaryotes. In the fruit fly Drosophila
melanogaster, where it has been most extensively
investigated, the ligand Delta binds the Notch
receptor, activating a secondary
messenger/transcription factor called SuH. Notch
signaling is employed during the development of the
fruit fly embryo and in the formation of major organs,
such as eyes and wings, in fruit fly larvae. A different
species of fly, Drosophila fleenogaster, has recently
been discovered. Pose a scientific question to
investigate whether the Notch/Delta signaling pathway
is conserved in D. fleenogaster.
Name
Date
Period
“The Central Dogma”
ribosome
protein
“TRANSLATION”
RNA
nucleus
RNA
DNA
“TRANSCRIPTION”
cytoplasm
“The Central Dogma”
• Transcription: making RNA
“The Central Dogma”
• Translation: making protein
Gly
Lys amino acid
Val
Tyr
Asp
tRNA
anticodon
codon
mRNA
ribosome
“The Central Dogma”
• Translation: making protein
Gly
Lys
Val
Tyr
Asp
Gly
Val
Tyr
Asp
“The Central Dogma”
• Translation: making protein
rRNA
tRNA
mRNA
Closure
On the piece of white paper from the
back, answer the following question:
How does the ribosome “read”
and translate the information in
an mRNA molecule into an
amino acid sequence?
Name
Date
Period
Scale
1 – 10