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M.R Shoja MD Shahid Sadoughi Medical Science Yazd. Iran ACUTE GLAUCOMA M.R.SHOJA 1 ANATOMY OF EYE ACUTE GLAUCOMA M.R.SHOJA 2 GLAUCOMA Glaucoma is the second leading cause of blindness in the world. In 2000 there were an estimated 66.8 million people with glaucoma , 6.7 million of whom had bilateral blindness secondary to glaucoma. Glaucoma has been definded as a progresssive optic neuropathy ACUTE GLAUCOMA M.R.SHOJA 3 Glaucoma classification Closed angle : - Primary secondary Open angle : - Primary - Secondary ACUTE GLAUCOMA M.R.SHOJA 4 Acute angle closure glaucoma - - Rapid increase in pressure of eye In Asia is more common 2-3 times more common in women than men Much higher in hyperopic eyes ACUTE GLAUCOMA M.R.SHOJA 5 Primary Angle Closure Glaucoma (PACG) Epidemiology: 1- Age 2-Gender Eastern Asia 3-Race less in black 4-Heriditary 5-Refractive Error 6-Seasonal Incidence (10% of all glaucoma , 5-10% bilatesal) ACUTE GLAUCOMA M.R.SHOJA 6 Precipitating factors 1-Mydriasis Darkness Medications Emotional upset - 2- Extreme Miosis - 3- Prone position ACUTE GLAUCOMA M.R.SHOJA 7 Dramatic symptoms Severe eye pain nausea and vomiting Headache Blurred vision Haloes around light Profuse tearing Fix mid-dilated pupil ACUTE GLAUCOMA M.R.SHOJA 8 Findings Diminished vision Ciliary flush , corneal Edema Elevated Iop (40-75 mmHg ) Shallow Anterior Chamber Dilated , vertically Oval nonreactive pupil. Cell and Flare in Ac Hyperemic Swollen optic disk ACUTE GLAUCOMA M.R.SHOJA 9 Exams & Tests Gonioscopy Tonometry Biomicroscopy Ophthalmoscopy Perimetry ACUTE GLAUCOMA M.R.SHOJA 10 Treatment B-adrenergic antagonist Timolol -adrenergic agonist : Apraclonidine Acetazolamid Trusopt Hyper osmotic agent Laser iriditomy PI Surgical iridectomy ACUTE GLAUCOMA M.R.SHOJA 11 Acute Angle Closure Glaucoma Hx: severe ocular pain with nausea and vomiting Pupil mid-dilated and oval Blurred vision Coloured haloes around lights due to corneal oedema Rx: emergency referral to ophthalmologist Miotics (Pilocarpine), beta-blockers (Timoptic) Aqueous suppressors (Acetazolamide) Hyperosmotic agents (glycerol, Mannitol) Once attack is broken, laser iridotomy indicated ACUTE GLAUCOMA M.R.SHOJA 12 Congenital glaucoma 1. 2. Primary Secondary (Sturg-weber ) ACUTE GLAUCOMA M.R.SHOJA 13 Primary congenital (Infantile glaucoma) 60% are diagnosed by 6 months 80% within first year 65% are male Bilateral in 70% cases Incidence being 1 in 25000 births ACUTE GLAUCOMA M.R.SHOJA 14 Eye exam Buphthalmos Corneal enlargement > 13mm Corneal edema Glaucomatous cupping ACUTE GLAUCOMA M.R.SHOJA 15 Symptoms Epiphora Photophobia Blepharospasm ACUTE GLAUCOMA M.R.SHOJA 16 Differential diagnosis Birth trauma Obstruction of lacrimal system Congenital syphilis, rubella Mucopolysaccahridoses CHED ACUTE GLAUCOMA M.R.SHOJA 17 Treatment Surgical 1. Goniotomy 2. Trabeculotomy ACUTE GLAUCOMA M.R.SHOJA 18