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Thyroid and Parathyroid Glands NUR 111 Functions of the Thyroid Pg. 1450 Metabolic rate Regulate protein, carbs and fat metabolism Increase RBC production Inc bone formation, decrease bone resorption of Ca+ Regulation of Metabolism Hormones T3 & T4 increase BMR Secretion controlled by hypothalamicpituitary-thyroid gland axis TRH » TSH » T3 & T4 (neg feedback) Protein and Iodine very important for T3 & T4 production Calcium and Phosphorus Balance Calcitonin (thyrocalcitonin, or TCT) Reduces bone resorption, lowers serum Ca+ Low serum Ca+ suppress TCT: Elevated serum Ca+ trigger TCT Causes of Hyperthyroidism Pg. 1482 Graves’ disease (Autoimmune) Toxic multinodular goiter Thyroid adenoma (benign tumor) Pituitary hyperthyroidism Excessive use of thyroid hormone Goiter and Exophthalmos in Graves' Disease Hyperthyroidism More common in women Lab assessment p.1485: T3, T4 TSH (Graves’) Thyroid Scan (RAIU) = increased Nursing Diagnosis Depends on condition of client Possible Dx. Include Imbalanced nutrition: > body requirements Fatigue Anxiety If large goiter present: what is priority??? Interventions Nonsurgical: monitor V/S, rest, cool environment Medications: PTU (propylthiouracil), SSKI, beta blockers Radioactive Iodine Therapy Remember eye care Interventions Surgical: total or subtotal thyroidectomy Preop = antithyroid meds, SSKI Postop = very important Monitor for Bleeding, respiratory distress, tetany, weak voice, thyroid storm (p.1487) Causes of Hypothyroidism Pg. 1489 Removal or destruction of thyroid Autoimmune (Hashimoto’s Disease) Iodine deficiency Medications (ex.Lithium) Hypothyroidism More common in women Lab assessment: T3, T4 TSH Monitor for depression Nursing Diagnosis Decreased cardiac output Ineffective breathing pattern Altered thought process Constipation Interventions Levothyroxine sodium (Synthroid) Avoid sedatives & narcotics Monitor vital signs Monitor for S&S of hyperthyroidism Family teaching re: mental status Myxedema Coma Hypothyroid Crisis --> rare but serious Etiology: acute illness/ trauma * rapid withdrawal of thyroid meds. use of sedatives / narcotics surgery exposure to cold Myxedema Coma temp / BP Na+ blood glucose Lactic acidosis Coma Collaborative Nursing Care IVF Airway IV: Synthroid Glucose Warming blanket Thyroiditis Acute – – Bacterial Pain Temp. Malaise Dysphagia TX Antibiotics Subacute – – Viral Temp. Chills Pain in jaw and/or ear TX ASA and steroids Thyroid Cancer Painless nodule in thyroid Treatment : RAI Surgery Parathyroid Glands: 4 in number can be removed w/ thyroid during surgery Parathyroid secretes: Parathyroid hormone (PTH) REMEMBER : Thyroid -> Calcitonin -> decreases serum calcium PTH - increases serum calcium Parathyroid Glands: Major Role: Regulate blood levels of calcium and phosphate PTH acts on: GI tract Kidney Bones If serum CA PTH secretion PTH - activates Vit. D --Increase calcium absorption from g.i. tract Remember:Thyroid also secretes Calcitonin Calcitonin helps--> keep Ca in bones maintain balance of Ca and Phosphorus Calcium -- 8.8 - 10.5 Phosphorus - 3 - 4.5 Hyperparathyroidism Pathophysiology PTH secretion = Ca+ Phos increased reabsorption of calcium by kidneys = increased excretion of Phosphate Causes tumors hyperplasia of parathyroid gland Data Collection : PTH renal calculi nephrocalcinosis bone decalcification serum Ca GI: anorexia, N&V, epigastric pain, constipation, M/S: fatigue & lethargy [serum Ca] > 12 mg/dl = mental status Complications: Renal Failure Fractures Collapse of vertebra Collaborative Management : focuses to decrease serum calcium Diuretic & Fluid Therapy Lasix /0.9% Na Cl Drug therapy Phosphates Calcitonin -miacalin spray Skel. Release Renal clearance Calcium Chelators - binds with Ca. -< dec. Levels of free calcium Parathyroidectomy Nursing Interventions : Diuretic & Fluid Rx: Monitor: cardiac function I&O renal status serum Ca Calcium Chelator Rx: Monitor: LFT, BUN & Creatinine, CBC Post - op care Parathyroidectomy Same as thyroidectomy Monitor for *** Tetany continuous spasm of hands / feet ---> convulsions calcium levels Calcium supplements ( Tums, Oscal ) Maintain airway Pathophysiology Hypoparathyroidism PTH Etiology (rare) thyroid / parathyroid surgery Hypomagnesemia Idiopathic Data Collection Hypoparathyroidism Tetany Check : • Chvostek’s • Trousseau’s • tingling • severe muscle cramping • irritability Collaborative management of care IV calcium gluconate Oscal Vitamin D High Calcium diet Magnesium IM or IV