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Pituitary Gland1 LH/FSH GH TSH ACTH ADH ACTH=Adrenocorticotropic Hormone ADH=Antidiuretic Hormone FSH=Follicle-Stimulating Hormone GH=Growth Hormone LH=Luteinizing Hormone TSH=Thyroid-Stimulating Hormone Adrenal Gland1,2 ACTH Cortisol Aldosterone Androgens ACTH=Adrenocorticotropic Hormone Parathyroid Glands1 PTH PTH= Parathyroid Hormone Ovaries ׀Testes1 Estradiol/ Progesterone FSH/LH Testosterone FSH=Follicle-Stimulating Hormone LH=Luteinizing Hormone Growth Hormone Pathway1,2 GH IGF-1 Adipose tissue GH=Growth Hormone IGF-1=Insulin-Like Growth Factor-1 Pancreas ׀Liver 1 Insulin Glucose balance Glucagon Posterior Pituitary Gland1,2 ADH ADH=Antidiuretic Hormone Glucose Metabolism1,2 GH ACTH Glucagon Insulin Cortisol ACTH=Adrenocorticotropic Hormone GH=Growth Hormone Thyroid Gland1 TH TSH TH=Thyroid Hormone TSH=Thyroid-Stimulating Hormone References: 1. Hiller-Sturmhöfel S, Bartke A. The endocrine system: an overview. Alcohol Health Res World. 1998;22(3):153-164. 2. Babler E, Betts K, et al, eds. Clinical Handbook of Pediatric Endocrinology. 2nd ed. St. Louis, MO: Quality Medical Publishing, Inc. 2013. ©2015 Genentech USA, Inc., Genentech, Inc., 1 DNA Way, So. San Francisco, CA 94080 NTR/101615/0115 11/15