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Fatma M. Shebl, MD, PhD
Assistant Professor of Epidemiology
Chronic Disease Epidemiology Division
60 College St., P.O. Box 208034
New Haven, CT 06520-8034
203-785-6232
203-785-6980 (FAX)
[email protected]
EDUCATION
PhD
Epidemiology, University of Maryland at Baltimore, Baltimore, MD
Dissertation: Incidence estimation when the disease assessment is subject
to misclassification error, with application to hepatitis C (Advisor:
Laurence Magder, Prof.)
2008
MS
Epidemiology and Preventive Medicine, University of Maryland at Baltimore,
Baltimore, MD
2006
MPH
University of Menoufia, Egypt
Thesis: Study of Protein calorie-malnutrition in post-hepatitic cirrhotic
patients attending Menoufia National Liver Institute
2002
MS
Internal Medicine, University of Alexandria, Egypt
Thesis: Comparative study of interleukin-8 lupus nephritis and diabetic
nephropathy and its correlation with disease activity and pathological
types
2000
MD
University of Alexandria, Egypt
1994
PROFESSIONAL EMPLOYMENT
Reseach Fellow
Division of Cancer Epidemiology and Genetics
(DCEG), NCI, NIH, Rockville, MD
Supervisor: Allan Hildesheim, PhD
Epidemiologist
University of Maryland, Baltimore and Maryland
Department of health and Mental Hygiene
Supervisors: Eileen Steinberg, Prof. and
Maureen Black, Prof.
2006-2008
Research Assistant
University of Maryland, Baltimore and Maryland
Department of health and Mental Hygiene
Supervisor: Eileen Steinberger, Prof.
University of Maryland, Baltimore
Supervisor: Thomas Strickland, Prof.
2005-2006
National Institute of Allergy and Infectious
Diseases (NIAID)-sponsored International
2004-2005
Research Assistant
Project Coordinator
2008-present
2002-2005
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Collaborations in Infectious Disease Research
(ICIDR) project of HCV/HEV, Egypt
Supervisor: Thomas Strickland, Prof.
Assistant Lecturer
Hepatic environmental health and public health,
National Liver Institute, University of Menoufia,
Egypt
Supervisor: Laila Dorgham, Prof.
Project Coordinator
National Institute of Allergy and Infectious
Diseases (NIAID)-sponsored International
Collaborations in Infectious Disease Research
(ICIDR) project of HCV/HEV, Egypt
Supervisor: Thomas Strickland, Prof.
2000-2002
Instructor
Hepatic environmental health and public health,
National Liver Institute, University of Menoufia,
Egypt
Supervisor: Laila Dorgham, Prof.
Internal Medicine, University of Alexandria, Egypt
Supervisor: Fathy Mohamed El-Belasy,
Prof.
1999-2002
Child and Maternal health
Physician
Child and Maternal health unit,
Moharam Bek, Governorate of Alexandria, Egypt
Supervisor: Samiha Mohamed, Dr.
1995-1996
House Officer
University of Alexandria, Egypt
1994-1995
Clinical Resident
2002-present
1996-1999
AWARDS/OTHER FUNDING
Mid-Atlantic Probability and
Statistics Day Award
Department of Mathematics and Statistics, University of
Maryland, Baltimore County. Recognition and cash
award for the method I developed to correct for
misclassification error in incidence estimation.
Fogarty Institute International
Scholarship
For epidemiology PhD students, University of
Maryland School of Medicine, Baltimore MD. The
award covered stipend, health care, and school tuition.
National Institute of Allergy and Infectious Diseases
Travel award for the Genetic
Epidemiology workshop, Brazil, (NIAID)-sponsored International Collaborations in
Infectious Disease Research (ICIDR).
Belo Horizonte
Trudy Bush Women’s Health
Research Award
University of Maryland School of Medicine.
Recognition and cash award for my work in women
and child health.
The ideal student honor award
Ministry of Education, Egypt. National recognition
award for my excellence in education and
extracurricular activities in high school.
Fatma M. Shebl
2007
2002-2005
2005
2004
1986, 1987
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PROFESSIONAL SERVICE
Facilitator
Member
DCEG Annual Ethics Training
DCEG Fellow Symposium
Planning Committee
2009-2010
2010
AD HOC JOURNAL REVIEW
Gastroenterology
Gastrointestinal Cancer: Targets and Therapy
Clinical Medicine Insights
Cancer Causes and Control
Virus Research
Nature Genetics
Journal of Infectious Disease
Cancer Epidemiology, Biomarkers and Prevention
Kidney International
Eastern Mediterranean Health Journal
Epidemiology and Infection
Journal of Acquired Immune Deficiency Syndrome
STATISTICAL PROGRAMS
SAS
SPSS
BRB ARRAY TOOL
MPLUS
R
DTREG
EPI CALC
PS POWER
TEACHING
Intermediate
Epidemiology course
Epidemiology and
Biostatistics Mentor
A 3 credit course at the Foundation of Advanced Science,
NIH
Mentor for clinical research fellow during his
dissertation on “Risk of Colorectal Neoplasia in the Screened
Population of Northeast Scotland”
2011
Epidemiology and
Biostatistics Mentor
Department of Epidemiology and Preventive Medicine,
University of Maryland. Mentored graduaste students to
analyze their data during their research practicum.
2007
Teaching Assistant
Department of Epidemiology and Preventive Medicine,
University of Maryland. Assisted teaching students of survey
research methodology course.
2006
Teaching Assistant
Department of Epidemiology and Preventive Medicine,
University of Maryland, Baltimore-sponsored training in
2004
Fatma M. Shebl
2010
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Cairo, Egypt. Assisted teaching graduate level students
survival analysis concepts and application using SPSS.
Epidemiology and
Biostatistics Instructor
Responsible for teaching “principle
of epidemiology, public health, environmental health and
biostatistics” in National Liver Institute, University of
Menoufia, Egypt
1999-2002
Clinical Instructor
Internal medicine division, school of Medicine, Alexandria,
Egypt. As a clinical resident, I clinically instructed 180-200
house officers over the course of 3 years.
1996-1999
TRAINING
Medical training
Clinical Resident
Internal Medicine, University of Alexandria, Egypt
1996-1999
Child and Maternal
health Physician
Child and Maternal health unit,
Moharam Bek, Governorate of Alexandria, Egypt
1995-1996
House Officer
University of Alexandria, Egypt
1994-1995
Other training
Grant writing course, NIH
Current Topics in Genome Analysis, NIH
Scientific Ethics Course for Facilitators, NCI
Time management course, NCI
SEER and MEDICARE Workshop, NIH
Scientists Teaching Science Workshop, NIH
Summer Curriculum in Cancer Prevention at the National Cancer Institute for the Molecular Prevention
Course, NIH
Teaching in Medical School Workshop, NIH
BRB-Array Tools Data Analysis Workshop, NIH
MATLAB Fundamentals and Programming Techniques, NIH
SAS Hands-On Workshop series, SAS foundation, MD
ABC course in Epidemiology and Biostatistics, University of Maryland training, Egypt
Good clinical practice workshop, NIH
ICITDR science writing workshop, NIH
Total Quality Management course for physicians, Cairo, Egypt
Genetic Epidemiology workshop, Brazil, Belo Horizonte
MEMBERSHIP
American Association of Cancer research
American Public Health Association
American Society of Preventive Oncology
Fatma M. Shebl
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BIBLIOGRAPHY
Peer Reviewed Publications:
1.
Shebl FM, Pfeiffer RM, Edlin BR, et al. IL28B-rs12979860 Genotype and Spontaneous Clearance
of Hepatitis C Virus in a Multi-Ethnic Cohort of Injection Drug Users:Evidence for a Supra-Additive
Association. J Infect dis (in press)
2.
Gadalla SM, Katki HA, Shebl FM, et al. The Relationship between DNA Methylation and Telomere
Length in Dyskeratosis Congenita. Aging Cell. 2011 Oct 8. [Epub ahead of print]
3.
Shebl FM, Dollard SC, Pfeiffer PM, et al.. Sexual behavior and human herpesvirus 8 seropositivity
among adults in a nationally-representative population-based study in Uganda. PLoS One.
2011;6(6):e21286. Epub 2011 Jun 21.
4.
Shebl FM, Andreotti G, Meyer TE et al. Metabolic Syndrome and Insulin Resistance in Relation to
Biliary Tract Cancer and Stone Risks: a Population-based Study in Shanghai, China. Br J Cancer.
2011 Sep 13. [Epub ahead of print]
5.
Shebl FM, Yu K, Landgren O, Goedert JJ, Rabkin CS. Increased Levels of Circulating Cytokines
with HIV-Related Immunosuppression. AIDS Res Hum Retroviruses. 2011 Sep 30. [Epub ahead of
print]
6.
Derbala MF, Amer AM, Almohanadi M, John A, Amin A, John A, Sharma M, Alkaabi SR, Al
Dweik NZ, Pasic F, Yaqoob R, Butt MT, Shebl FM. Hepatitis C Genotype 4 with Normal
Transaminases: Histological changes, Schistosomiasis, and Response to Treatment. J Viral Hepat.
2010 Nov 25. [Epub ahead of print]
7.
Biryahwaho B, Dollard SC, Pfeiffer PM, Shebl FM, Munuo S, Amin MM, Wolfgang H, Parsons R,
and Mbulaiteye SM. Gender and geographic patterns of human herpesvirus 8 infection in a
nationally-representative population-based sample in Uganda. J Infect Dis. 2010 Nov 1;202(9):134753.; Sep 23. [Epub ahead of print]
8.
Shebl FM, Maeder D, Shao Y et al. In the Absence of HCV Infection, Interferon Stimulated Gene
Expression in Liver is Not Associated with IL28B Genotype. Gastroenterology. 2010
Oct;139(4):1422-4. Epub 2010 Aug 25
9.
Shebl FM, Engels EA, Goedert JJ, Chaturvedi AK. Pulmonary infections and risk of lung cancer
among persons with AIDS. J Acquir Immune Defic Syndr. 2010; Aug 23. [Epub ahead of print
10.
Shebl FM, El-Kamary SS. Diabetes Mellitus, Obesity and Hepatocellular Carcinoma: The Jury Is
Still Out. Am J Gastroenterol. 2010; Sep;105(9):2116-7.
11.
Shebl FM, Andreotti G, Rashid A, et al. Diabetes in relation to Biliary Tract Cancer and Stones: a
Population-based Study in Shanghai, China. Br J Cancer. 2010; Jun 29;103(1):115-9. Epub 2010 Jun
1
12.
Shebl FM, Pinto LA, García-Piñeres A, et al. Comparison of mRNA and protein measures of
cytokines following vaccination with HPV-16 L1 virus like particles. Cancer Epidemiol Biomarkers
Prev. 2010; Apr;19(4):978-81. Epub 2010 Mar 23
Fatma M. Shebl
Page 5 of 9
13.
Derbala MF, Shebl FM, Rashid AH, et al. Microalbuminuria in Hepatitis C Genotype 4: Relation to
Liver Histology, Viral load, and effect of treatment. World J Gastroenterol. 2010; Mar
14;16(10):1226-1231.
14.
Saleh DA, Shebl FM, El-Kamary SS, et al. Incidence and risk factors for community-acquired
hepatitis C infection from birth to 5 years of age in rural Egyptian children. Trans R Soc Trop Med
Hyg. 2010; May;104(5):357-63. Epub 2010 Feb 12
15.
Shebl FM, Bhatia K, Engels EA. Salivary gland and nasopharyngeal cancers in individuals with
acquired immunodeficiency syndrome in United States. Int J Cancer. 2010; May 15;126(10):2503-8.
16.
Shebl FM, El-Kamary SS, Saleh DA, et al. Prospective cohort study of mother-to-infant infection
and clearance of hepatitis C in rural Egyptian villages. J Med Virol. 2009;81:1024-31.
17.
Shebl F, Poppell CE, Zhan M, et al. Measuring health behaviors and landline telephones: potential
coverage bias in a low-income, rural population. Public Health Rep. 2009;124:495-502.
18.
Derbala M, Rizk N, Al-Kaabi S, Amer A, Shebl F, et al.: Adiponectin changes in HCV-Genotype 4:
relation to liver histology and response to treatment. J Viral Hepat. 2009; 16(10):689-96.
19.
Oberlander SE, Shebl FM, Magder LS, Black MM. Moving on: Adolescent mothers leaving
multigenerational households. J Clin Child Adolesc Psychol. 2009; Jan;38(1):62-74
20.
Derbala MF, El Dweik NZ, Al Kaabi SR, Al-Marri AD, Pasic F, Bener AB, Shebl FM, Amer AM,
Butt MT, Yakoob R, John A, Al Mohanadi M, Al Khinji MA. Viral kinetic of HCV genotype-4
during pegylated interferon alpha 2a: ribavirin therapy. J Viral Hepat. 2008; 15:291-299. Epub 2008
May 15
21.
Faisel H, Majoko F, Shebl F, Lindsay P. Twin pregnancies in Cardiff and Vale of Glamorgan over
four decades: Natural twinning is on the increase. Eur J Obstet Gynecol Reprod Biol. 2008;
Aug;139(2):164-8.
22.
Saleh D, Shebl FM, Abdel-Hamid M, et al. Incidence and risk factors for hepatitis C infection in a
cohort of pregnant women in rural Egypt. Trans R Soc Trop Med Hyg. 2008; Sep;102(9):921-8.
23.
Steinberger EK, Poppell C, Zhan M, Shebl F, Groves C, Hopkins A, Bienia M, Dwyer D. Colorectal
Cancer Test Use -- Maryland, 2002 to 2006. MMWR Morb Mortal Wkly Rep. 2007; Sep 14;56(36):
932-936.
24.
El-Hawary MA, El-Raziky MS, Esmat G, Soliman H, Abouzied A, El-Raziky M, El-Akel W, ElSayed R, Shebl F, Shaheen AA, El-Karaksy H. Assessment of hepatic fibrosis in pediatric cases with
hepatitis C virus in Egypt. World J Gastroenterol. 2007; May 28;13(20):2846-51.
25.
Stoszek SK, Abdel-Hamid M, Saleh DA, El Kafrawy S, Narooz S, Hawash Y, Shebl FM, El Daly
M, Said A, Kassem E, Mikhail N, Engle RE, Sayed M, Sharaf S, Fix AD, Emerson SU, Purcell RH,
Strickland GT. High prevalence of hepatitis E antibodies in pregnant Egyptian women. Trans R Soc
Trop Med Hyg. 2006; Feb;100(2):95-101. Epub 2005 Oct 28.
26.
Stoszek SK, Abdel-Hamid M, Narooz S, El Daly M, Saleh DA, Mikhail N, Kassem E, Hawash Y, El
Kafrawy S, Said A, El Batanony M, Shebl FM, Sayed M, Sharaf S, Fix AD, Strickland GT.
Fatma M. Shebl
Page 6 of 9
Prevalence of and risk factors for hepatitis C in rural pregnant Egyptian women. Trans R Soc Trop
Med Hyg. 2006; Feb;100(2):102-7. Epub 2005 Nov 9.
Non-Peer Reviewed Publications:
1.
Shebl FM. Incidence estimation when the disease assessment is subject to misclassification error,
with application to hepatitis C. Dissertation. University of Maryland, Baltimore. Graduate School,
Division of Epidemiology and Preventive Medicine. 2008.
2.
Poppell CF, Shebl FM, Hopkins A, Zhan M, Steinberger EK, Groves C, Dwyer DM, A populationBased Statewide Survey on Cancer Screening and Behavioral Risk Factors. Maryland Cancer
Survey, Report 2006. Available at
http://www.fha.state.md.us/cancer/surveillance/pdf/MCS20006.pdf. Last accessed October 01, 2007.
3.
Steinberger E, Poppell C, Shebl FM, Hopkins A, Israel E, Groves C, Bienia M, Dwyer D, Maryland
Cancer Survey, Montgomery County Latino County Cancer Survey Report 2006. Available at
http://www.fha.state.md.us/cancer/pdf/MCLCS_2005.pdf. Last accessed October 01, 2007.
4.
Shebl FM. Study of Protein calorie-malnutrition in post-hepatitic cirrhotic patients attending
Menoufia National Liver Institute. Thesis. University of Menoufia, School of Medicine. 2002.
5.
Shebl FM. Study of interleukin-8 in Lupus nephritis and Diabetic nephropathy and its correlation
with disease activity and pathological types. Thesis. University of Alexandria, School of Medicine.
2000.
6.
El-Hawary M, El-Raziky M, Esmat G, soliman H, Abouzied A, el-Akel W, et al. Factors associated
with fibrosis progression in HCV-infected children in Egypt. [abstract] Liver International.
2006;26(1):S1 111.
7.
Rizk N, Derbala MF, Al-Kaabi SR, Amer A, Shebl F, et al.: Adiponectin changes in HCV-genotype
4: relation to liver histology and response to treatment. [abstract] Hepatology 2008; 48(4): 508.
8.
Derbala MF, Shebl FM, Rashid AH, Amer AM, Bener A: Microalbuminuria in hepatitis c genotype
4: relation to liver histology, viral load, and effect of treatment. [abstract] Hepatology 2009; 50(4):
1352.
9.
Umesh B, Fatma MS, Andrew JP, Georgina LH, Charles SR, Emad E-O. T2012 Cytokine Gene
Polymorphisms, Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of
Northeast Scotland. [abstract] Gastroenterology;138:S-613.
Fatma M. Shebl
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ORAL AND POSTER PRESENTATIONS
1.
The 61st annual meeting of the American association of the study of liver disease AASLD, Boston:
October 29- November 3 2010 “Absent HCV Infection, IL28B Genotype is Not Associated with
Interferon Stimulated Gene Expression in Liver”
2.
The 61st annual meeting of the American association of the study of liver disease AASLD, Boston:
October 29- November 3 2010 “Hepatitis C genotype 4 with normal transaminases and
schistosomiasis co-infection: Histological changes, Response Rate, Late Relapse, and Hematological
adverse effect”
3.
Digestive Disease Week DDW, New Orleans, May 1-5 2010, “Cytokine Gene Polymorphisms,
Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of Northeast Scotland”
4.
AACR 101st Annual meeting, Washington, DC: April 17-21 2010, “Spectrum of Malignancies in
Patients with End-Stage Renal Disease”
5.
The 60th annual meeting of the American association of the study of liver disease AASLD, Boston:
October 30- November 3 2009, “Microalbuminuria in hepatitis C genotype 4: relation to liver
histology, viral load, and effect of treatment”
6.
AACR 100th Annual meeting, San Diego, CA: April 18-22 2009, “Pulmonary infections and risk of
lung cancer among people with AIDS”
7.
The 13th International Symposium on Viral Hepatitis and Liver Disease in Washington, DC: March
20-24, 2009 “Clearance of hepatitis C viremia in children born to, and living with, HCV-infected
mothers is associated with long-lasting HCV-specific cell mediated immune responses”
8.
16th CROI Conference on Retroviruses and Opportunistic Infections Montreal, Canada February 811, 2009 “Forty-Fold Elevated Risk for Lymphoepithelial Carcinoma of Salivary Gland Among
People with AIDS in the United States”
9.
The 59th annual meeting of the American association of the study of liver disease AASLD, San
Francisco: October 31- November 4 2008, “Adiponectin changes in HCV-genotype 4: relation to
liver histology and response to treatment”
10.
The 58th annual meeting of the American association of the study of liver disease AASLD, Boston:
November 2-6 2007, “Viral Kinetics Of HCV Genotype 4 During Pegylated Interferon Alpha 2a –
Ribavirin Therapy ”
11.
APHA 135th Annual Meeting & Exposition Washington, DC: November 2007, “How incidence is
affected by outcome misclassification in the presence of conditional dependence”
12.
APHA 135th Annual Meeting & Exposition Washington, DC: November 2007, “Is the prevalence of
cervical cancer screening lower among obese women?”
13.
Mid-Atlantic Probability and Statistics Day, University of Maryland Baltimore County (UMBC),
MD: April 2007, “Impact of Outcome Misclassification errors and Conditional Dependence on
Cumulative incidence Estimates”
14.
APHA 134th Annual Meeting & Exposition Boston, MA: November 2006, "Does inclusion of only
those with landline telephones bias the results of health risk surveys?"
Fatma M. Shebl
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15.
The 13th World Conference on Tobacco OR Health, Washington, DC: July, 2005, Washington DC
“What are the risk reduction behaviors and demographics that distinguish cigar from cigarette
smokers?”
16.
The 13th World Conference on Tobacco OR Health, Washington, DC: July, 2005, Washington DC
“Association between cigarette quitting attempts and other risk reduction behaviors”
17.
The 13th World Conference on Tobacco OR Health, Washington, DC: July, 2005, Washington DC
“Low rates of cigarette smoking among elderly in Maryland. Is it a cohort effect or differential
quitting rates?”
18.
HCP 7th annual workshop, Cairo: March, 2005, Cairo “Transmission of Hepatitis E Virus in Rural
Communities”
19.
AEAS Bi-Annual Conference: December 2004, Cairo, Egypt. “Hepatitis C virus (HCV) infection in
mother and children in Rural Egypt”
20.
ASTMH 53rd annual meeting: November 2004, Miami “HCV infection in rural Egyptian children”
21.
ICTDR 13th meeting: May 2004, Bethesda “Risk factors for hepatitis C virus in Egyptian women and
children”
22.
ASTMH 52st annual meeting: December 2003, Philadelphia “Hepatitis C transmission in rural
Egyptian women and children”
23.
ASTMH 51st annual meeting: November 2002, Denver “Mother- infant transmission of hepatitis E in
Egyptian rural communities”
24.
HCP 6th annual meeting, Cairo: February, 2001, Cairo “Mother- infant transmission of hepatitis C in
Egyptian rural communities”
25.
National Liver Institute Annual Scientific Conference: 22-23 November 2000, Menofia
“implementation of total quality management (TQM) in menoufia national liver institute”
Fatma M. Shebl
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