Download BIO 330 Cell Biology Lecture Outline Spring 2011 Chapter 17: Cell

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BIO 330 Cell Biology
Lecture Outline
Spring 2011
Chapter 17: Cell Adhesion, Cell Junctions, and Extracellular Structures
I. Cell-Cell Recognition and Adhesion
A. Transmembrane proteins mediate cell-cell adhesion
Homophilic vs. heterophilic interactions
CAMs
Cadherins
B. Role of carbohydrate groups in recognition and adhesion
Lectins
Selectins
Survival of erythrocytes
II. Cell-Cell Junctions
A. Adhesive (anchoring) junctions
Adherens junctions
Desmosomes
B. Tight junctions
Structure
Prevention of paracellular transport
Creates cell polarity
C. Gap junctions
Direct electrical and chemical communication
III. Extracellular Matrix of Animal Cells
A. Collagens
Procollagen
B. Elastin
C. Matrix of proteoglycans
Glycosaminoglycans (GAGs)
Proteoglycans are proteins covalently bound to GAGs
D. Hyaluronate (hyaluronic acid)
Free GAG
E. Adhesive glycoproteins
Fibronectins
Affect cell shape and movement
Laminins
Bind cells to the basal lamina
Integrins – membrane-bound receptors which bind fibronectins, laminin & collagen
Focal adhesions
Hemidesmosomes
Some cell signaling activities
BIO 330 Cell Biology
Lecture Outline
Spring 2011
F. Glycocalyx
Layer of carbohydrate-rich fluid around animal cells
IV. Plant Cell Surface – Cell walls
A. Structural framework & permeability barrier
B. Cell wall structure
Cellulose microfibrils
Polysaccharides
Pectins, extensins, lignins
C. Synthesis of plant cell walls
Middle lamella
Primary cell wall
Secondary cell wall
D. Plasmodesmata
Connect the cytoplasm of adjacent plant cells
Channel runs through the cell wall and is lined by plasma membrane from each cell
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