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SCHOOL OF ENGINEERING COURSE PROPOSAL FORM Course Name*: Statistics for Biomedical Sciences Course Proposer*: Niall Anderson Have you confirmed that the appropriate resources are in place (finance, teaching staff, IT)*: Yes Have you confirmed that the appropriate support services are in place (library, computing services)*: Yes Normal Year Taken*: Postgraduate Course Level*: PG Available to Visiting Students?* Available to All Students Display in Visiting Student Prospectus: Yes SCQF Credits*: 10 Credit Level*1: 11 Home Subject Area*: Postgrad (School of Engineering) Other Subject Area: Course Organiser*: Niall Anderson Course Secretary: ? % not taught by this institution: 0% Collaboration Information: Course organiser from School of Clinical Sciences & Community Health, CMVM, University of Edinburgh Total Contact Teaching Hours*: 20 Any costs to be met by students: None Pre-requisites (course name & None code)*: Co-requisites (course name & code)*: None Prohibited None Combinations (course name & code)*: Visiting Students Pre-requisites: None Short Description*: The course provides an introduction to key concepts and topics in the statistical methods typically used in biomedical sciences, with particular attention to the principles of good experimental design and appropriate methods of analysis. It will also provide some training in practical data analysis using specialist statistical software. Keywords2: Statistics, clinical trials, experimental design, randomisation, ANOVA, reproducibility, diagnostic tests, regression Fee Code if invoiced at Course level: Not applicable Default Course Mode of Study*: Classes & Assessment, excl. centrally arranged exam Default Delivery Period*: Semester 1 Course Type*: Standard Summary of Intended Students should be familiar with the basic principles Learning Outcomes*: underlying statistical thinking, including topics such as types of data, the relationship of population to sample, sampling methods, confidence intervals, hypothesis testing and experimental design and randomisation. They should understand and be able to apply simple one and two-group parametric tests, correlation coefficients, simple linear regression models, and simple fixed-effect analysis of variance models. They should be able to analyse correctly method comparison and reproducibility studies and use the appropriate quantities to measure performance of diagnostic and prognostic tests. They should develop competence in implementing the above methods in statistical software. Special Arrangements: None Components of Assessment (inc. % weightings)*: Project = 100% Exam Information* (please remove 2nd Sit if not applicable): None Syllabus/Lecture List: 1. Introduction to principles of statistical inference, types of data and graphical and simple summary measures 2. Basic probability and probability distributions 3. Confidence intervals – principles and simple 1 & 2 group continuous and categorical examples 4. Hypothesis testing – examples as session 3. principles and same 5. Correlation and simple linear regression 6. Study design principles – randomisation and blocking 7. Study design principles – clinical trials and power issues 8. One and Two-way analysis of variance models 9. Method comparison and reproducibility methods 10. Diagnostic testing – sensitivity, specificity, PPV, NPV and ROC curves Study Pattern/Course 10 x 1 hour lectures; 5 x 2 hour practical sessions Structure: Benchmark Statements Assessed: Teaching Load* (select from attached list): Reading Lists: 10 x 1 hour lectures; 5 x 2 hour practical sessions 1. Statistics at Square One, Ninth Edition (1997). Swinscow, TDJ. BMJ (Download at http://www.bmj.com/statsbk/) 2. Medical Statistics at a Glance (2000). Petrie, A and Sabin, C. Blackwell. 3. Practical Statistics for Medical Research (1991) Altman, D.G. Chapman and Hall/ CRC. Convenor of Board of Examiners: ? Footnotes: * Indicates mandatory fields. 1. Normally: Undergraduate Courses: Years 1 and 2 = Level 8 Year 3 = Level 9 Year 4 = Level 10 Year 5 = Level 11. MSc Courses 2. = Level 11. Keywords are used to help staff/students find a course when searching the DRPS (Degree Regulations and Programme of Study).