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MYCAFRICA
A network to promote Medical Mycology in Africa
Martha Mushi1 , Olga Nduwimana2, Nyambura Moremi1, Mourine Kangogo2 ,
Edna Shiko2, Oliver Bader3, Uwe Groß3,4, Stephen Mshana1, and Christine Bii2
1. Department of Microbiology and Immunology, Catholic University of Health and Allied Sciences - Bugando, Mwanza, Tanzania
2. Medical Mycology Unit, Center for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya
3. Institute for Medical Microbiology, University Medical Center, Göttingen, Germany
4. Göttingen International Health Network, Göttingen, Germany
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Our (Göttingen) collaborations with African
research groups
• Ghana
• Chad
• Kenya
• South Sudan
• Tanzania
• Uganda
Collaboration partners involved in funding
requests
DAAD
Deutscher Akademischer Austausch Dienst
German Academic Exchange Service
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Previous project: Epidemiology of Cryptococcus molecular types in
and around Nairobi
MSc. Mourine Kangogo
Sampling of environmental sites and clinical
isolates available from routine diagnostics
DAAD
Deutscher Akademischer Austausch Dienst
German Academic Exchange Service
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Previous project: Epidemiology of Cryptococcus molecular types in
and around Nairobi
In Nairobi:
Initial culture and morphologic identification (India ink / Niger seed agar) of Cryptococci
Reference strains
example isolates
VGI
VGI
VNI
VGI
VNII
VNI
VGI
VGI
VNI
VNI
VGIII
VGIV
VGI
VGII
VNIV
VNIII
VNII
VNI
In Göttingen:
Molecular identification of subtype by URA3-RFLP
EUCAST broth microdilution (FLZ, AMB, 5FC)
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Previous project: Epidemiology of oral Candida carriage among HIV
patients in a small health center in Sahr, Chad (cross-sectional study design)
cand. med. Liliane Taverne
C
>50% coated tongue
D
Median rhomboid
glossitis with central
atrophy
E
With involvement
of the palate
C-E severe symptoms
Impact of HAART in a collective of HIV-infected patients
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Building a regional diagnostic network in East Africa
Mwanza
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Building a regional diagnostic network in East Africa
- To create a larger conscience for fungal infections
- To enhance mycological diagnostics and support teaching
- To produce valid epidemiologic data for fungal infections
and drug resistances
-> Meetings/Workshops √
-> Homepage √
-> Joint research projects √
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Main project: Aspergillus fumigatus azole resistance
 Epidemiology in Germany: Poster 361
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Main project: Aspergillus fumigatus azole resistance
Test sampling in / around Nairobi, Kenya
Test sampling in Tanzania
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First spin-off project: fungal colonization during eardrum inflammation
Problem: Patients with inflamed, perforated eardrums reporting to Mwanza hospital
Fungal culture done on site,
ID and AST in Göttingen
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Summary
Brought together laboratories from Nairobi (KY) and Mwanza (TZ) to collaborate on
scientific projects (Aspergillus fumigatus azole resistance)
... sampling partially pending official authorization
Contact to Kampala (UG) established
Spin-off projects (ear infections) started, “awareness” among local clinicians raised
DAAD
Deutscher Akademischer Austausch Dienst
German Academic Exchange Service
mycafrica.wordpress.com