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A. Left ventricular scar as late enhancement on cardiac magnetic resonance. Increasing LV scar is correlated with an increased risk of ventricular arrhythmias. (Reproduced with permission from Kwong RY, Chan AK, Brown KA, et al. Impact of unrecognized myocardial scar detected by cardiac magnetic resonance imaging on event-free survival in patients presenting with signs or symptoms of coronary artery disease. Circulation. 2006 Jun 13;113(23):2733-2743.) B. Four stages of left atrial tissue fibrosis based on 3D delayed enhancement magnetic resonance imaging. Increasing percentages of LA fibrosis are correlated with progressively increasing risk of AF recurrence after AF ablation. Normal left atrial wall is displayed in blue; fibrotic changes are in green and white. (Reproduced with permission from Marrouche NF, Wilber D, Hindricks G, et al. Association of atrial tissue fibrosis Source: APPROACH TO THE PATIENT WITH CARDIAC ARRHYTHMIAS, Hurst's The Heart, 14e identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF stud, JAMA. 2014 Feb 5;311(5):498-506.) C. Integration of Citation: Fuster V, Harrington Narula J, in Eapen ZJ. Hurst's The Heart, 14e; 2017 Available at: http://mhmedical.com/ May image 04, coronary artery anatomy from computed RA, tomography commercially available electroanatomic map during epicardial ablation.Accessed: Multimodality 2017 integration is routinely used in electrophysiological studies and ablation, providing the advantages of structural/functional characterization of tissue, Copyright 2017 McGraw-Hill Education. rights reserved increasing safety during© navigation of catheters within All or external to the patient’s heart, and decreasing use of traditional fluoroscopy. (Reproduced with permission from Zeppenfeld K, Tops LF, Bax JJ, et al: Images in cardiovascular medicine. Epicardial radiofrequency catheter ablation of ventricular