Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
BIBLIOGRAPHY ADENOVIRUS Occupational relevance 1. Brummitt CF, Cherrington JM, Katzenstein DA, Juni BA, Van Drunen N, Edelman C et al. Nosocomial adenovirus infections: molecular epidemiology of an outbreak due to adenovirus 3a. Journal of Infectious Diseases 1988;158:423-32. 2. Curtis S, Wilkinson GW, Westmoreland D. An outbreak of epidemic keratoconjunctivitis caused by adenovirus type 37. Journal of Medical Microbiology 1998;47:91-4. 3. Finn A, Anday E, Talbot GH. An epidemic of adenovirus 7a infection in a neonatal nursery: course, morbidity, and management. Infection Control & Hospital Epidemiology 1988;9:398-404. 4. Sanchez MP, Erdman DD, Torok TJ, Freeman CJ, Matyas BT. Outbreak of adenovirus 35 pneumonia among adult residents and staff of a chronic care psychiatric facility. Journal of Infectious Diseases 1997;176:760-3. 5 Sidebotham D, Anderson B, Featherstone D, Schug SA. Transfer of adenovirus infection from patient to anaesthetist during emergency tracheal intubation. Anaesthesia & Intensive Care 1997;25:83-5. Adenovirus and Coeliac Disease – Medline Search 1. Wieser H. The precipitating factor in coeliac disease. [Review] [63 refs]. Baillieres Clinical Gastroenterology 1995;9:191-207. Ref ID: 1 2. Kagnoff MF. Celiac disease: adenovirus and alpha gliadin. [Review] [50 refs]. Current Topics in Microbiology & Immunology 1989;145:67-78. Ref ID: 9 3. Kagnoff MF. Coeliac disease: genetic, immunological and environmental factors in disease pathogenesis. [Review] [50 refs]. Scandinavian Journal of Gastroenterology Supplement 1985;114:45-54. Ref ID: 20 4. Mantzaris GJ, Karagiannis JA, Priddle JD, Jewell DP. Cellular hypersensitivity to a synthetic dodecapeptide derived from human adenovirus 12 which resembles a sequence of A-gliadin in patients with coeliac disease. Gut 1990;31:668-73. Ref ID: 7 5. Barbeau WE, Novascone MA, Elgert KD. Is celiac disease due to molecular mimicry between gliadin peptide-HLA class II molecule-T cell interactions and those of some unidentified superantigen?. [Review] [59 refs]. Molecular Immunology 1997;34:535-41. Ref ID: 13 86 6. Ellis HJ, Doyle AP, Sturgess RP, Ciclitira PJ. Coeliac disease: characterisation of monoclonal antibodies raised against a synthetic peptide corresponding to amino acid residues 206-217 of A-gliadin. Gut 1992;33:1504-7. 7. Devery JM, Bender V, Penttila I, Skerritt JH. Identification of reactive synthetic gliadin peptides specific for coeliac disease. International Archives of Allergy & Applied Immunology 1991;95:356-62. 8. Mantzaris G,.Jewell DP. In vivo toxicity of a synthetic dodecapeptide from A gliadin in patients with coeliac disease. Scandinavian Journal of Gastroenterology 1991;26:392-8. 9. Karagiannis JA, Priddle JD, Jewell DP. Cell-mediated immunity to a synthetic gliadin peptide resembling a sequence from adenovirus 12. Lancet 1987;1:884-6. 10. Arato A, Kosnai I, Szonyi L, Toth M. Frequent past exposure to adenovirus 12 in coeliac disease. Acta Paediatrica Scandinavica 1991;80:1101-2. 11. Mantzaris GJ, Priddle JD, Jewell DP. T lymphocyte responses to a synthetic peptide from the human intestinal adenovirus 12 in coeliac disease. Journal of Clinical & Laboratory Immunology 1990;31:75-9. 12. Howdle PD, Blair Zajdel ME, Smart CJ, Trejdosiewicz LK, Blair GE, Losowky MS. Lack of a serologic response to an E1B protein of adenovirus 12 in coeliac disease. Scandinavian Journal of Gastroenterology 1989;24:282-6. 13. Kagnoff MF, Paterson YJ, Kumar PJ, Kasarda DD, Carbone FR, Unsworth DJ et al. Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease. Gut 1987;28:995-1001. 14. Lahdeaho ML, Parkkonen P, Reunala T, Maki M, Lehtinen M. Antibodies to E1b protein-derived peptides of enteric adenovirus type 40 are associated with celiac disease and dermatitis herpetiformis. Clinical Immunology & Immunopathology 1993;69:300-5. 15. Lahdeaho ML, Lehtinen M, Rissa HR, Hyoty H, Reunala T, Maki M. Antipeptide antibodies to adenovirus E1b protein indicate enhanced risk of celiac disease and dermatitis herpetiformis. International Archives of Allergy & Immunology 1993;101:272-6. 16 Carter MJ, Willcocks MM, Mitchison HC, Record CO, Madeley CR. Is a persistent adenovirus infection involved in coeliac disease? Gut 1989;30:1563-7. 17. Lawler M, Humphries P, O'Farrelly C, Hoey H, Sheils O, Jeffers M et al. Adenovirus 12 E1A gene detection by polymerase chain reaction in both the normal and coeliac duodenum. Gut 1994;35:1226-32. 18. Vesy CJ, Greenson JK, Papp AC, Snyder PJ, Qualman SJ, Prior TW. Evaluation of celiac disease biopsies for adenovirus 12 DNA using a multiplex polymerase chain reaction. Modern Pathology 1993;6:61-4. 19. Mahon J, Blair GE, Wood GM, Scott BB, Losowsky MS, Howdle PD. Is persistent adenovirus 12 infection involved in coeliac disease? A search for viral DNA using the polymerase chain reaction. Gut 1991;32:1114-6. 87 20. Kagnoff MF, Austin RK, Hubert JJ, Bernardin JE, Kasarda DD. Possible role for a human adenovirus in the pathogenesis of celiac disease. Journal of Experimental Medicine 1984;160:1544-57. ADENOVIRUS AND OBESITY Adenovirus and Obesity – Medline Search 1. Dhurandhar NV, Kulkarni PR, Ajinkya SM, Sherikar AA, Atkinson RL. Association of adenovirus infection with human obesity. Obesity Research 1997;5:464-9. Adenovirus and Obesity – Science Citation Index Search 1 Atkinson RL. A 33-year-old woman with morbid obesity. Jama-Journal Of The American Medical Association 2000;283:3236-43. ADENOVIRUS AND MYOCARDIAL DISEASE Adenovirus and Myocardial Disease - Medline Search 1. Bowles NE,.Towbin JA. Molecular aspects of myocarditis. [Review] [43 refs]. Current Opinion in Cardiology 1998;13:179-84. 2. Hyypia T. Etiological diagnosis of viral heart disease. [Review] [39 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1993;88:25-31. 3. Bowles KR, Gibson J, Wu J, Shaffer LG, Towbin JA, Bowles NE. Genomic organization and chromosomal localization of the human Coxsackievirus B-adenovirus receptor gene. Human Genetics 1999;105:354-9. Ref ID: 5 4. Ito M, Kodama M, Masuko M, Yamaura M, Fuse K, Uesugi Y et al. Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis [see comments]. Circulation Research 2000;86:275-80. 5. Grumbach IM, Heim A, Pring-Akerblom P, Vonhof S, Hein WJ, Muller G et al. Adenoviruses and enteroviruses as pathogens in myocarditis and dilated cardiomyopathy. Acta Cardiologica 1999;54:83-8. 6. Akhtar N, Ni J, Stromberg D, Rosenthal GL, Bowles NE, Towbin JA. Tracheal aspirate as a substrate for polymerase chain reaction detection of viral genome in childhood pneumonia and myocarditis. Circulation 1999;99:2011-8. 7. Pauschinger M, Bowles NE, Fuentes-Garcia FJ, Pham V, Kuhl U, Schwimmbeck et al. Detection of adenoviral genome in the myocardium of adult patients with idiopathic left ventricular dysfunction. Circulation 1999;99:1348-54. 8. Lozinski GM, Davis GG, Krous HF, Billman GF, Shimizu H, Burns JC. Adenovirus myocarditis: retrospective diagnosis by gene amplification from formalin-fixed, paraffin embedded tissues. Human Pathology 1994;25:831-4. 88 9. Ni J, Bowles NE, Kim YH, Demmler G, Kearney D, Bricker JT et al. Viral infection of the myocardium in endocardial fibroelastosis. Molecular evidence for the role of mumps virus as an etiologic agent. Circulation 1997;95:133-9. 10. Lum LC, Wong KT, Lam SK, Chua KB, Goh AY. Adenovirus in EV71-associated hand, foot, and mouth disease [letter]. Lancet 2000;355:146-7. 11. Eck M, Greiner A, Kandolf R, Schmausser B, Marx A, Muller-Hermelink HK. Active fulminant myocarditis characterized by T-lymphocytes expressing the gamma-delta T-cell receptor: a new disease entity? American Journal of Surgical Pathology 1997;21:1109-12. Adenovirus and myocardial disease - Science Citation Index Search 1 Davydova J, Pankuweit S, Crombach M, Eckhardt H, Strache D, Faulhammer P et al. Detection of viral and bacterial protein in endomyocardial biopsies of patients with inflammatory heart muscle disease? Herz 2000;25:233-9. 2 Pankuweit S, Portig I, Eckhardt H, Crombach M, Hufnagel G, Maisch B. Prevalence of viral genome in endomyocardial biopsies from patients with inflammatory heart muscle disease. Herz 2000;25:221-6. ADENOVIRUS AND CARCINOMA Adenovirus and Carcinoma - Medline Search 1. Vasudevan DM,.Vijayakumar T. Viruses in human oral cancers. [Review] [70 refs]. Journal of Experimental & Clinical Cancer Research 1998;17:27-31. 2. Doerfler W. The insertion of foreign DNA into mammalian genomes and its consequences: a concept in oncogenesis. [Review] [99 refs]. Advances in Cancer Research 1995;66:313-44. 3. Mackowiak PA. Microbial oncogenesis. [Review] [212 refs]. American Journal of Medicine 1987;82:79-97. 4. Calvin M. Evolution and cancer. Carcinogenesis; a Comprehensive Survey 1985;10:51-63. 5. Flint SJ. Cellular transformation by adenoviruses. [Review] [219 refs]. Pharmacology & Therapeutics 1984;26:59-88. 6. Doerfler W. Uptake, fixation, and expression of foreign DNA in mammalian cells: the organization of integrated adenovirus DNA sequences. [Review] [200 refs]. Current Topics in Microbiology & Immunology 1982;101:127-94. 7. 85. Wyke JA. Oncogenic viruses. [Review] [85 refs]. Journal of Pathology 1981;135:39- 8. Wadell G, Hammarskjold ML, Winberg G, Varsanyi TM, Sundell G. Genetic variability of adenoviruses. [Review] [42 refs]. Annals of the New York Academy of Sciences 1980;354:16-42. 9. Nastag E,.Nastag E. Data on the involvement of some viruses in the etiopathogeny of human tumors. [Review] [224 refs]. Virologie 1979;30:217-28. 89 10. Swenberg JA. Chemical- and virus-induced brain tumors. [Review] [63 refs]. National Cancer Institute Monographs 1977;46:3-10. 11. Manos JP,.Walker EM, Jr. Viruses and human cancer. Annals of Clinical & Laboratory Science 1983;13:201-6. 12. Albert DM. The role of viruses in the development of ocular tumors. [Review] [57 refs]. Ophthalmology 1980;87:1219-25. 13. Kato Y, Yamamoto T, Sawada T, Kobayashi M. Early stage of human adenovirus type 12-inoculated retinal tissue of F344 newborn rat. Pathology International 1996;46:54856. 14. Weiss RS, McArthur MJ, Javier RT. Human adenovirus type 9 E4 open reading frame 1 encodes a cytoplasmic transforming protein capable of increasing the oncogenicity of CREF cells. Journal of Virology 1996;70:862-72. 15. Javier RT. Adenovirus type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats. Journal of Virology 1994;68:3917-24. 16. Kato Y, Matsumoto H, Kobayashi M, Okada Y, Kawaoi A. Genomic DNA analysis of rat retinal tumor induced by adenovirus type 12. Acta Pathologica Japonica 1991;41:8117. 17. Ogawa K. Embryonal neuroepithelial tumors induced by human adenovirus type 12 in rodents. 1. Tumor induction in the peripheral nervous system. Acta Neuropathologica 1989;77:244-53. 18. Akagi K, Murai K, Haddada H, Levine AS, Patch CT. Mitogenic and antimitogenic transforming growth factors secreted by adenovirus 2- and simian virus 40-transformed haMSter cells: possible roles in promoting tumorigenesis. Cancer Research 1987;47 :4086 92. 19. Rhim JS, Fujita J, Arnstein P, Aaronson SA. Neoplastic conversion of human keratinocytes by adenovirus 12-SV40 virus and chemical carcinogens. Science 1986;232:3858. 20. Rhim JS, Sanford KK, Arnstein P, Fujita J, Jay G, Aaronson SA. Human epithelial cell carcinogenesis: combined action of DNA and RNA tumor viruses produces malignant transformation of primary human epidermal keratinocytes. Carcinogenesis; a Comprehensive Survey 1985;9:57-66. 21. Kobayashi M, Mukai N, Solish SP, Sawada T, Pomeroy ME. Cell-mediated immunity in F 344 rats bearing intraocular tumors derived from human adenovirus 12-induced retinal tumor. Gann 1983;74:706-11. 22. Paraskeva C, Brown KW, Gallimore PH. Adenovirus-cell interactions early after infection: in vitro characteristics and tumourigenicity of adenovirus type 2-transformed rat liver epithelial cells. Journal of General Virology 1982;58 Pt 1:73-81. 23. Gallimore PH, McDougall JK, Chen LB. Malignant behaviour of three adenovirus-2transformed brain cell lines and their methyl cellulose-selected sub-clones. International Journal of Cancer 1979;24:477-84. 90 24. Nakajima T,.Mukai N. Cell origin of human adenovirus type 12-induced subcutaneous tumor in Syrian haMSters. Acta Neuropathologica 1979;45:187-94. 25. Ohmori M. Activated endogenous viruses of tumor induced by human adenovirus: an electron microscope study. Experimental & Molecular Pathology 1978;29:260-71. 26. Asch BB, McCormick KJ, Stenback WA, Trentin JJ. Virus-specific markers and virus-like particles in cell lines of tumors produced by CELO virus in Syrian golden haMSters. Journal of the National Cancer Institute 1978;61:163-71. 27. Chino F. Character of the tumors developing in young haMSters by the mixed cell transplantation of para-adeno-virus 12 and SV40 tumors-the similarity to the tumors induced by para-adenovirus 7. Acta Pathologica Japonica 1977;27:321-9. 28. Lee KC,.Mak S. Adenovirus type 12 DNA sequences in primary haMSter tumors. Journal of Virology 1977;24:408-11. 29. Mukai N, Nakajima T, Freddo T, Jacobson M, Dunn M. Retinoblastoma-like neoplasm induced in C3H/BifB/Ki strain mice by human adenovirus serotype 12. Acta Neuropathologica 1977;39:147-55. 30. Takeuchi M,.Nitta K. Induction of murine tumors in adult mice by a combination of either avian sarcoma virus or human adenovirus and syngeneic mouse embryo cells. Cancer Research 1983;43:328-32. 31. Csata S, Kulcsar G, Horvath J, Nasz I, Ongradi J, Verebelyi A. Study of antibodies to adenoviruses in patients with tumors of the urogenital system. International Urology & Nephrology 1982;14:115-9. 32. Dorak MT, Lawson T, Machulla HK, Darke C, Mills KI, Burnett AK. Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia [see comments]. Blood 1999;94:694-700. 33. Wold WS, Mackey JK, Rigden P, Green M. Analysis of human cancer DNA's for DNA sequence of human adenovirus serotypes 3, 7, 11, 14, 16, and 21 in group B1. Cancer Research 1979; 39:3479-84. 34. Mackey JK, Green M, Wold WS, Rigden P. Analysis of human cancer DNA for DNA sequences of human adenovirus type 4. Journal of the National Cancer Institute 1979;62:236. 35. Draca P, Damjanovic J, Draca T, Vukovic V. Viruses as possible etiological factors in human genital cancer. European Journal of Gynaecological Oncology 1992;13:193-9. 36. Magun A. Gastric cancer and adenovirus. Gastroenterology 1990;98:799-800. 37. Harnden DG. Chromosomes, cancer genes and carcinogenesis. Progress in Clinical & Biological Research 1983;132C:371-82. 38. Oker-Blom N. Viruses and human cancer. Acta Microbiologica Academiae Scientiarum Hungaricae 1979;26:157-60. 39.Melnick JL. Human studies following models of tumorigenesis by DNA tumor viruses in animals. Bulletin of the Pan American Health Organization 1978;12:28-33. 91 Adenovirus and carcinoma – Science Citation Index Search 1 Ruther U, Nunnensiek C, Muller HAG, Rothe B, Dobbertin J, Bader H et al. Evidence of EBV-DNA, HSV(I+II)-DNA, HHV6-DNA, CMV-DNA, and adenovirus-2E1A and ADENOVIRIS-5E1B in mucous-membrane of bronchogenic-carcinoma, pleural mesothelioma, sarcoidosis, and intrinsic asthma. Tumordiagnostik & Therapie 1994;15:121-7. ADENOVIRUS AND LUNG DISEASE Adenovirus and Lung Disease - Medline Search 1. Hogg JC. Latent adenoviral infection in the pathogenesis of emphysema: the Parker B. Francis Lectureship. [Review] [34 refs]. Chest 2000;117:282S-5S. 2. McFerran JB, Adair B, Connor TJ. Adenoviral antigens (CELO, QBV, GAL). [Review] [20 refs]. American Journal of Veterinary Research 1975;36:527-9. 3. Smith CB,.Overall JC, Jr. Clinical and epidemiologic clues to the diagnosis of respiratory infections. [Review] [35 refs]. Radiologic Clinics of North America 1973;11:26178. 4. Pagtakhan RD, Reed MH, Chernick V. Is bronchiolitis in infancy an antecedent of chronic lung disease in adolescence and adulthood? Journal of Thoracic Imaging 1986;1:3440. 5. Simila S, Linna O, Lanning P, Heikkinen E, Ala-Houhala M. Chronic lung damage caused by adenovirus type 7: a ten-year follow-up study. Chest 1981;80:127-31. 6. Vitalis TZ, Keicho N, Itabashi S, Hayashi S, Hogg JC. A model of latent adenovirus 5 infection in the guinea pig (Cavia porcellus). American Journal of Respiratory Cell & Molecular Biology 1996;14:225-31. 7. Vitalis TZ, Kern I, Croome A, Behzad H, Hayashi S, Hogg JC. The effect of latent adenovirus 5 infection on cigarette smoke-induced lung inflammation. European Respiratory Journal 1998;11:664-9. 8. Yonemaru M, Kasuga I, Kusumoto H, Kunisawa A, Kiyokawa H, Kuwabara S et al. Elevation of antibodies to cytomegalovirus and other herpes viruses in pulmonary fibrosis. European Respiratory Journal 1997;10:2040-5. 9. Sly PD, Soto-Quiros ME, Landau LI, Hudson I, Newton-John H. Factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. Archives of Disease in Childhood 1984;59:935-9. 10. Matsuse T, Hayashi S, Kuwano K, Keunecke H, Jefferies WA, Hogg JC. Latent adenoviral infection in the pathogenesis of chronic airways obstruction. American Review of Respiratory Disease 1992;146:177-84. 11. Lowenberg A,.Orie NG. Viral, mycoplasma and bacterial infections in nurses with symptoms of respiratory diseases. Scandinavian Journal of Respiratory Diseases 1976;57:290-300. 12. Massie R,.ArMStrong D. Bronchiectasis and bronchiolitis obliterans post respiratory syncytial virus infection: think again. Journal of Paediatrics & Child Health 1999;35:497-8. 92 13. Avital A, Shulman DL, Bar-Yishay E, Noviski N, Schachter J, Krausz Y et al. Differential lung function in an infant with the Swyer-James syndrome. Thorax 1989;44:298302. ADENOVIRUS AND ASTHMA Adenovirus and asthma – Medline Search 1. Hogg JC. Childhood viral infection and the pathogenesis of asthma and chronic obstructive lung disease. [Review] [38 refs]. American Journal of Respiratory & Critical Care Medicine 1999;160:S26-S28. 2. Filipp G. Experiments on the role of virus infections in the pathogenesis of bronchial asthma. The role of innate or acquired insufficiency or ergotropic adaptation in the mechanism of genesis of bronchial asthma. Allergologia et Immunopathologia 1976;4:15-28. 3. Simila S, Linna O, Lanning P, Heikkinen E, Ala-Houhala M. Chronic lung damage caused by adenovirus type 7: a ten-year follow-up study. Chest 1981;80:127-31. 4. Macek V, Sorli J, Kopriva S, Marin J. Persistent adenoviral infection and chronic airway obstruction in children [see comments]. American Journal of Respiratory & Critical Care Medicine 1994;150:7-10. 5. Hurd ER, Dowdle W, Casey H, Ziff M. Virus antibody levels in systemic lupus erythematosus. Arthritis & Rheumatism 1972;15:267-74. 6. Macek V, Dakhama A, Hogg JC, Green FH, Rubin BK, Hegele RG. PCR detection of viral nucleic acid in fatal asthma: is the lower respiratory tract a reservoir for common viruses? Canadian Respiratory Journal 1999;6:37-43. 7. West JA, Dakhama A, Khan MA, Vedal S, Hegele RG. Community study using a polymerase chain reaction panel to determine the prevalence of common respiratory viruses in asthmatic and nonasthmatic children. Journal of Asthma 1999;36:605-12. 8. Grieco MH, Sherrid MV, Edsall J. Acute diffuse pneumonia with asthma. Associated with adenoviral infection. New York State Journal of Medicine 1977;77:410-2. 9. Spector SL, English GM, McIntosh K, Farr RS. Adenovirus in the sinuses of an asthmatic patient with apparent selective antibody deficiencies. American Journal of Medicine 1973;55:227-31. Ref ID: 14 Adenovirus and asthma – science citation index papers 1. Hegele RG, Hayashi S, Hogg JC, Pare PD. Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory-tract infections. American Journal Of Respiratory And Critical Care Medicine 1995;151:1659-65. 2. Marin J, Jeler-Kacar D, Levstek V, Macek V. Persistence of viruses in upper respiratory tract of children with asthma. Journal Of Infection 2000;41:69-72. 93 3. Diaz PV, Calhoun WJ, Hinton KL, Avendano LF, Gaggero A, Simon V et al. Differential effects of respiratory syncytial virus and adenovirus on mononuclear cell cytokine responses. American Journal Of Respiratory And Critical Care Medicine 1999;160:1157-64. 4. Ruther U, Nunnensiek C, Muller HAG, Rothe B, Dobbertin J, Bader H et al. Evidence of EBV-DNA, HSV(I+II)-DNA, HHV6-DNA, CMV-DNA, and adenovirus-2E1A and ADENOVIRIS-5E1B in mucous-membrane of bronchogenic-carcinoma, pleural mesothelioma, sarcoidosis, and intrinsic asthma. Tumordiagnostik & Therapie 1994;15:121-7. SINUSITIS 1. Ramadan H H, Farr R W and Wetmore S J. Adenovirus and respiratory syncytial virus in chronic sinusitis using polymerase chain reaction. Laryngoscope 1997;107(7):923-5 CHRONIC HUMAN ADENOVIRUS PNEUMONIA 1. Rosman F C, Mistchenko A S, Ladenheim H S, do Nascimento J P, Outani H N, Madi K, and Lenzi H L. Acute and chronic human adenovirus pneumonia: cellular and extracellular matrix components. Pediatric Pathology & Laboratory Medicine 1996;16(3):521-41. CHRONIC FATIGUE SYNDROME 1. Buchwald D, Ashley R L, Pearlman T, Kith P, Komaroff A L Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50(1):25-30. DERMATITIS HERPETIFORMIS 1. Handley J, O’Neill H, Connolly J, Burrows D. Adenovirus-12 and dermatitis herpetiformis. Acta Dermato-Venereologica 1993;73:430-2. CYTOMEGALOVIRUS Occupational relevance 1. Adler SP. Nosocomial transmission of cytomegalovirus. Pediatric Infectious Disease 1986;5 :239-46. 2. Adler SP. Molecular epidemiology of cytomegalovirus: viral transmission among children attending a day care center, their parents, and caretakers. Journal of Pediatrics 1988;112:366-72. 3. Ahlfors K, Ivarsson S-A, Johnsson T, Renmarker K. Risk of cytomegalovirus infection in nurses and congenital infection in their offspring. Acta Paediatrica Scandinavica 1981;70. 4. Bale JFJ, Zimmerman B, Dawson JD, Souza IE, Petheram, SJ et al. Cytomegalovirus transmission in child care homes. Archives of Pediatrics & Adolescent Medicine 1999;153:759. 5. Bale JJ,.Murph JR. The risk of cytomegalovirus infection in hospital personnel and child care providers: A review. Pediatric Reviews & Communications 1991;5:233-46. 94 6. Boussemart T, Baudon JJ, Garbarg-Chenon A, Costil J. Cytomegalovirus, pregnancy and occupational hazard. Archives de Pediatrie 1998;5:24-6. 7. Brady MT. Cytomegalovirus infections: Occupational risk for health professionals. American Journal of Infection Control 1986;14. 8. Brady MT, Demmler GJ, Anderson DC. Cytomegalovirus infection in pediatric house officers: susceptibility to and rate of primary infection. Infection Control 1987;8:329-32. 9. Demmler GJ, Yow MD, Spector SA, Reis SG, Brady MT, Anderson DC et al. Nosocomial cytomegalovirus infections within two hospitals caring for infants and children. Journal of Infectious Diseases 1987;156:9-16. 10. Dworsky ME, Welch K, Cassady G, Stagno S. Occupational risk for primary cytomegalovirus infection among pediatric health-care workers. New England Journal of Medicine 1983;309. 11. Friedman HM, Lewis MR, Nemerofsky DM, Plotkin SA. Acquisition of cytomegalovirus infection among female employees at a pediatric hospital. Pediatric Infectious Disease 1984;3. 12. Gerberding JL, Bryant-LeBlanc CE, Nelson K. Risk of transmitting the human immunodeficiency virus, cytomegalovirus, and hepatitis B virus to healthcare workers exposed to patients with AIDS and AIDS-related conditions. Journal of Infectious Diseases 1987;156. 13. Gerberding JL. Incidence and prevalence of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and cytomegalovirus among healthcare personnel at risk for blood exposure: Final report from a longitudinal study. Journal of Infectious Diseases 1994;170:1410-7. 14. Ghebrekidan H, Ruden U, Cox S, Wahren B, Grandien M. Prevalence of herpes simplex virus types 1 and 2, cytomegalovirus, and varicella-zoster virus infections in Eritrea. Journal of Clinical Virology 1999;12:53-64. 15. Hatherley LI. Is primary cytomegalovirus infection an occupational hazard for obstetric nurses? A serological study. Infection Control 1986;7. 16. Hibberd PL. Patients, needles, and healthcare workers: Understanding the epidemiology, pathophysiology, and transmission of the human immunodeficiency virus, hepatitis B and C, and cytomegalovirus. Journal of Intravenous Nursing 1995;18:S22-S31. 17. Jackson LA, Stewart LK, Solomon SL, Boase J, Alexander ER, Heath JL et al. Risk of infection with hepatitis A, B or C, cytomegalovirus, varicella or measles among child care providers. Pediatric Infectious Disease Journal 1996;15:584-9. 18. Lipscomb JA, Linnemann CC, Jr., Hurst PF, Myers MG, Stringer W, Moore P et al. Prevalence of cytomegalovirus antibody in nursing personnel. Infection Control 1984;5:5138. 19. Murph JR, Baron JC, Brown CK, Ebelhack CL, Bale JJ. The occupational risk of cytomegalovirus infection among day-care providers. JAMA 1991;265:603-8. 95 20. Pass RF, Hutto C, Lyon D, Cloud G. Increased rate of cytomegalovirus infection among day care center workers. Pediatric Infectious Disease Journal 1990;9:465-70. 21. Scheifele D, Bortolussi R, Gold R. Cytomegalovirus: An occupational hazard? CMAJ 1984;131 . 22. Teyssier-Cotte C, Delepine A, Defrancourt C, Drobacheff C, Coaquette A. Hepatitis and cytomegalovirus infection in a woman in contact with AIDS patients. Archives des Maladies Professionnelles et de Medecine du Travail 1998;59:24-7. 23. Tookey P,.Peckham CS. Does cytomegalovirus present an occupational risk? Archives of Disease in Childhood 1991;66:1009-10. 24. Tookey P,.Logan S. Occupational risk of cytomegalovirus. Reviews in Medical Microbiology 1994;5:33-8. 25. Volpi A, Pica F, Cauletti M, Pana A, Rocchi G. Cytomegalovirus infection in day care centers in Rome, Italy: Viral excretion in children and occupational risk among workers. Journal of Medical Virology 1988;26:119-25. 26. Yow MD, Lakeman AD, Stagno S, Reynolds RB, Plavidal FJ. Use of restriction enzymes to investigate the source of a primary cytomegalovirus infection in a pediatric nurse. Pediatrics 1982;70:713-6. CYTOMEGALOVIRUS AND GUILLAIN-BARRE SYNDROME Cytomegalovirus and Guillain-Barre Syndrome – Medline Search 1. Hughes RA, Hadden RD, Gregson NA, Smith KJ. Pathogenesis of Guillain-Barre syndrome. [Review] [296 refs]. Journal of Neuroimmunology 1999;100:74-97. 2. van der Meche FG, Visser LH, Jacobs BC, Endtz HP, Meulstee J, van D et al. Guillain-Barre syndrome: multifactorial mechanisms versus defined subgroups. [Review] [20 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S99-102. 3. Merrill JE, Graves MC, Mulder DG. Autoimmune disease and the nervous system. Biochemical, molecular, and clinical update. [Review] [130 refs]. Western Journal of Medicine 1992;156:639-46. 4. Bale JF, Jr. Human cytomegalovirus infection and disorders of the nervous system. [Review] [150 refs]. Archives of Neurology 1984;41:310-20. 5. Schoenberg BS. Epidemiology of Guillain-Barre syndrome. [Review] [25 refs]. Advances in Neurology 1978;19:249-60. 6. Heni N, Heissmeyer HH, Baumgartner M. [Clinical course of cytomegalovirus infection in adults]. [German]. Deutsche Medizinische Wochenschrift 1986;111:499-503. 7. Van Koningsveld R, van Doorn PA, Schmitz PI, Ang CW, van der Meche FG. Mild forms of Guillain-Barre syndrome in an epidemiologic survey in The Netherlands. Neurology 2000;54:620-5. 8. Jacobs BC, Rothbarth PH, van der Meche FG, Herbrink P, Schmitz PI, de et al. The spectrum of antecedent infections in Guillain-Barre syndrome: a case-control study. Neurology 1998;51:1110-5. 96 9. Hao Q, Saida T, Kuroki S, Nishimura M, Nukina M, Obayashi H et al. Antibodies to gangliosides and galactocerebroside in patients with Guillain-Barre syndrome with preceding Campylobacter jejuni and other identified infections. Journal of Neuroimmunology 1998;81:116-26. 10. Melendez-Vasquez C, Redford J, Choudhary PP, Gray IA, Maitland P, Gregson NA et al. Immunological investigation of chronic inflammatory demyelinating polyradiculoneuropathy. Journal of Neuroimmunology 1997;73:124-34. 11. Merelli E, Sola P, Faglioni P, Poggi M, Montorsi M, Torelli G. Newest human herpesvirus (HHV-6) in the Guillain-Barre syndrome and other neurological diseases. Acta Neurologica Scandinavica 1992;85:334-6. 12. Boucquey D, Sindic CJ, Lamy M, Delmee M, Tomasi JP, Laterre EC. Clinical and serological studies in a series of 45 patients with Guillain-Barre syndrome. Journal of the Neurological Sciences 1991;104:56-63. 13. Dowling PC, Bosch VV, Cook SD, Chmel H. Serum immunoglobulins in GuillainBarre syndrome. Journal of the Neurological Sciences 1982;57:435-40. 14. Dowling PC,.Cook SD. Role of infection in Guillain-Barre syndrome: laboratory confirmation of herpesviruses in 41 cases. Annals of Neurology 1981;9 Suppl:44-55. 15. Dowling P, Menonna J, Cook S. Cytomegalovirus complement fixation antibody in Guillain-Barre syndrome. Neurology 1977;27:1153-6. 16. Wahren B,.Link H. Antibodies to Epstein-Barr virus and cytomegalovirus in GuillainBarre syndrome. Journal of the Neurological Sciences 1976;28:129-38. 17. Ang CW, Jacobs BC, Brandenburg AH, Laman JD, van der Meche FG, Osterhaus et al. Cross-reactive antibodies against GM2 and CMV-infected fibroblasts in Guillain-Barre syndrome. Neurology 2000;54:1453-8. 18. Khalili-Shirazi A, Gregson N, Gray I, Rees J, Winer J, Hughes R. Antiganglioside antibodies in Guillain-Barre syndrome after a recent cytomegalovirus infection [see comments]. Journal of Neurology, Neurosurgery & Psychiatry 1999;66:376-9. 19. Yuki N,.Tagawa Y. Acute cytomegalovirus infection and IgM anti-GM2 antibody. Journal of the Neurological Sciences 1998;154:14-7. 20. Sindern E, Oreja-Guevara C, Raulf-HeiMSoth M, Baur X, Malin JP. A longitudinal study of circulating lymphocyte subsets in the peripheral blood during the acute stage of Guillain-Barre syndrome. Journal of the Neurological Sciences 1997;151:29-34. 21. Jacobs BC, van Doorn PA, Groeneveld JH, Tio-Gillen AP, van der Meche FG. Cytomegalovirus infections and anti-GM2 antibodies in Guillain-Barre syndrome. Journal of Neurology, Neurosurgery & Psychiatry 1997;62:641-3. 97 22. Irie S, Saito T, Nakamura K, Kanazawa N, Ogino M, Nukazawa T et al. Association of anti-GM2 antibodies in Guillain-Barre syndrome with acute cytomegalovirus infection. Journal of Neuroimmunology 1996;68:19-26. 23. Adelmann M,.Linington C. Molecular mimicry and the autoimmune response to the peripheral nerve myelin P0 glycoprotein. Neurochemical Research 1992;17:887-91. 24. Oomes PG, van der Meche FG, Markus-Silvis L, Meulstee J, Kleyweg RP. In vivo effects of sera from Guillain-Barre subgroups: an electrophysiological and histological study on rat nerves. Muscle & Nerve 1991;14:1013-20. 25. Frampton G, Winer JB, Cameron JS, Hughes RA. Severe Guillain-Barre syndrome: an association with IgA anti-cardiolipin antibody in a series of 92 patients. Journal of Neuroimmunology 1988;19:133-9. 26. Visser LH, van der Meche FG, Meulstee J, Rothbarth PP, Jacobs BC, Schmitz PI et al. Cytomegalovirus infection and Guillain-Barre syndrome: the clinical, electrophysiologic, and prognostic features. Dutch Guillain-Barre Study Group [see comments]. Neurology 1996;47:668-73. 27. Hughes R, Atkinson P, Coates P, Hall S, Leibowitz S. Sural nerve biopsies in Guillain-Barre syndrome: axonal degeneration and macrophage-associated demyelination and absence of cytomegalovirus genome [see comments]. Muscle & Nerve 1992;15:568-75. 28. Winer JB, Briggs D, Welsh K, Hughes RA. HLA antigens in the Guillain-Barre syndrome. Journal of Neuroimmunology 1988;18:13-6. 29. Granstrom M, Linde A, Wahren B. Antibody response to cytomegalovirus: a comparison between adult patients with neurological disease and uncomplicated infection. Journal of Medical Virology 1981;7:127-34. 30. Link H, Wahren B, Norrby E. Pleocytosis and immunoglobulin changes in cerebrospinal fluid and herpesvirus serology in patients with Guillain-Barre syndrome. Journal of Clinical Microbiology 1979;9:305-16. 31. Schmitz H,.Enders G. Cytomegalovirus as a frequent cause of Guillain-Barre syndrome. Journal of Medical Virology 1977;1:21-7. 32. Tsukaguchi M, Tagawa Y, Takeuchi H, Yuki N. IgM anti-GM2 antibody in a patient with Guillain-Barre syndrome subsequent to cytomegalovirus hepatitis cross reacts with N acetylgalactosaminyl GD1a [letter]. Journal of Neurology, Neurosurgery & Psychiatry 1998;65:407-8. 33. Nakamura K, Irie S, Kanazawa N, Saito T, Tamai Y. Anti-GM2 antibodies in Guillain-Barre syndrome with acute cytomegalovirus infection. Annals of the New York Academy of Sciences 1998;845:423. 34. Numazaki K,.Chiba S. Cytomegalovirus infection and Guillain-Barre syndrome [letter; comment]. Neurology 1997;49:1472-3. 35. Mendizabal JE,.Bassam BA. Guillain-Barre syndrome and cytomegalovirus infection during pregnancy. Southern Medical Journal 1997;90:63-4. 98 36. Lecocq P, Majid S, Girard B, I. [Guillain-Barre syndrome complicating cytomegalovirus infection in an immunocompetent adult]. [French]. Revue de Medecine Interne 1995;16:847-9. 37. Kuller JA, Katz VL, McCoy MC, Hansen WF. Pregnancy complicated by GuillainBarre syndrome. Southern Medical Journal 1995;88:987-9. 38. Perry A, Mehta J, Iveson T, Treleaven J, Powles R. Guillain-Barre syndrome after bone marrow transplantation. Bone Marrow Transplantation 1994;14:165-7. 39. Brown WF. Sural nerve biopsies in Guillain-Barre syndrome: axonal degeneration and macrophage-associated demyelination and absence of cytomegalovirus genome [letter; comment]. Muscle & Nerve 1993;16:112. 40. Nakauchi CM, Linhares AC, Gomes ML, Maruyama K, Kanzaki LI, Azevedo VN. Antibody to human T-lymphotropic virus in a patient with Guillain-Barre syndrome (case report) [published erratum appears in Rev Inst Med Trop Sao Paulo 1991 NovDec;33(6):following table of contents]. Revista do Instituto de Medicina Tropical de Sao Paulo 1991;33:329-31. Ref ID: 47 41. Hurley TJ, Brunson AD, Archer RL, Lefler SF, Quirk JG, Jr. Landry Guillain-Barre Strohl syndrome in pregnancy: report of three cases treated with plasmapheresis. Obstetrics & Gynecology 1991;78:482-5. 42. Albers JW. AAEE case report :4: Guillain-Barre syndrome. Muscle & Nerve 1989;12:705-11. 43. May SE, Caudle MR, Kleinman GE. Landry-Guillain-Barre-Strohl syndrome in pregnancy. A report of two cases. Journal of Reproductive Medicine 1989;34:550-2. 44. Donaghy M, Gray JA, Squier W, Kurtz JB, Higgins RM, Richardson AJ et al. Recurrent Guillain-Barre syndrome after multiple exposures to cytomegalovirus. American Journal of Medicine 1989;87:339-41. 45. Larsen JK,.Melgaard B. Simultaneous neuroinfection with cytomegalovirus and herpes simplex virus in an immunocompetent adult. Journal of Internal Medicine 1989;226:59-61. 46. Hart IK,.Kennedy PG. Guillain-Barre syndrome associated with cytomegalovirus infection. Quarterly Journal of Medicine 1988;67:425-30. 47. Mozes B, Pines A, Sayar Y, Kaplinsky N, Frankl O. Guillain-Barre syndrome associated with acute cytomegalovirus mononucleosis syndrome. European Neurology 1984;23:237-9. 48. Pepose JS. A theory of virus-induced demyelination in the Landry-Guillain-Barre syndrome. Journal of Neurology 1982;227:93-7. 49. Glaser R, Brennan R, Berlin CM. Guillain-Barre syndrome associated with EpsteinBarr virus in a cytomegalovirus-negative patient. Developmental Medicine & Child Neurology 1979;21:787-90. 99 50. Magnussen CR,.Patanella HP. Herpes simplex virus and recurrent laryngeal nerve paralysis. Report of a case and review of the literature. Archives of Internal Medicine 1979;139:1423-4. 51. Arnold AG, Lawrence DS, Corbitt G. Cytomegalovirus infection and the GuillainBarre syndrome. Postgraduate Medical Journal 1978;54:112-4. 52. Heni N, Beck U, Enders G, Schmitz G. [Guillain-Barre- polyneuroradiculitis and Fisher-syndrome in cytomegalovirus infections (author's transl)]. [German]. Archiv fur Psychiatrie und Nervenkrankheiten 1976;222:305-14. 53. Reller LB. Epstein-Barr virus and Guillain-Barre syndrome. Lancet 1973;1:151. 54. Klemola E, Weckman N, Haltia K, Kaariainen L. The Guillain-Barre syndrome associated with acquired cytomegalovirus infection. Acta Medica Scandinavica 1967;181:603-7. Cytomegalovirus and Guillain-Barre Syndrome - science-citation index search 1. Cinque P, Marenzi R, Ceresa D. Cytomegalovirus infections of the nervous system. Intervirology 1997;40:85-97. 2. Lecocq P, Majid S, Buttazig G. Guillain-Barre-Syndrome as the presenting manifestation of cytomegalovirus infection in a healthy adult. Revue De Medecine Interne 1995;16:847-9. 3. Schottlender JG, Lombardi D, Toledo A, Otero C, Mazia C, Menga G. Respiratory failure associated with Guillain-Barre syndrome. Medicina-Buenos Aires 1999;59:705-9. 4. Sinardi D, Spada A, Marino A, Mondello E. A case of central nervous system vasculitis related to an episode of Guillain-Barre syndrome. Critical Care 2000;4:245-7. CYTOMEGALOVIRUS AND CORONARY HEART DISEASE Cytomegalovirus and Coronary Heart Disease - Medline Search 1. Benitez RM. Atherosclerosis: an infectious disease?. [Review] [12 refs]. Hospital Practice (Office Edition) 1985;34:79-82. 2. Leinonen M,.Saikku P. Infections and atherosclerosis. [Review] [118 refs]. Scandinavian Cardiovascular Journal 2000;34:12-20. 3. High KP. Atherosclerosis and infection due to Chlamydia pneumoniae or cytomegalovirus: weighing the evidence. [Review] [42 refs]. Clinical Infectious Diseases 1999;28:746-9. 4. Sinha N,.Garg N. Role of infections in the pathogenesis of atherosclerotic coronary artery disease: past, present and future. [Review] [49 refs]. Indian Heart Journal 2000;52:7985. 5. de Boer OJ, van der Wal AC, Becker AE. Atherosclerosis, inflammation, and infection. [Review] [64 refs]. Journal of Pathology 2000;190:237-43. 6. Bruggeman CA, Marjorie HJ, Nelissen-Vrancken G. Cytomegalovirus and atherogenesis. [Review] [81 refs]. Antiviral Research 1999;43:135-44. 100 7. Epstein SE, Zhou YF, Zhu J. Potential role of cytomegalovirus in the pathogenesis of restenosis and atherosclerosis. [Review] [16 refs]. American Heart Journal 1999;138:S476S478. 8. Danesh J. Coronary heart disease, Helicobacter pylori, dental disease, Chlamydia pneumoniae, and cytomegalovirus: meta-analyses of prospective studies. American Heart Journal 1999;138:S434-S437. 9. Epstein SE, Zhou YF, Zhu J. Infection and atherosclerosis: emerging mechanistic paradigMS. [Review] [130 refs]. Circulation 1999;100:e20-e28. 10. Kuvin JT,.Kimmelstiel CD. Infectious causes of atherosclerosis. [Review] [56 refs]. American Heart Journal 1999;137:216-26. 11. Cammarota G, Pasceri V, Papa A, Cianci R, Gasbarrini A, Fedeli P et al. Helicobacter pylori infection and ischaemic heart disease. [Review] [12 refs]. Italian Journal of Gastroenterology & Hepatology 1998;30 Suppl 3:S304-S306. 12. Cheng JW,.Rivera NG. Infection and atherosclerosis--focus on cytomegalovirus and Chlamydia pneumoniae. [Review] [47 refs]. Annals of Pharmacotherapy 1998;32:1310-6. 13. Vercellotti GM. Effects of viral activation of the vessel wall on inflammation and thrombosis. [Review] [24 refs]. Blood Coagulation & Fibrinolysis 1998;9 Suppl 2:S3-S6. 14. Mehta JL, Saldeen TG, Rand K. Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease [see comments]. [Review] [97 refs]. Journal of the American College of Cardiology 1998;31:1217-25. 15. Mattila KJ, Valtonen VV, Nieminen MS, Asikainen S. Role of infection as a risk factor for atherosclerosis, myocardial infarction, and stroke. [Review] [203 refs]. Clinical Infectious Diseases 1998;26:719-34. 16. Adam E, Melnick JL, DeBakey ME. Cytomegalovirus infection and atherosclerosis. [Review] [65 refs]. Central European Journal of Public Health 1997;5:99-106. 17. Ellis RW. Infection and coronary heart disease. [Review] [44 refs]. Journal of Medical Microbiology 1997;46:535-9. 18. Melnick JL, Adam E, DeBakey ME. Cytomegalovirus and atherosclerosis. [Review] [30 refs]. Archivum Immunologiae et Therapiae Experimentalis 1996;44:297-302. 19. Melnick JL, Adam E, DeBakey ME. Cytomegalovirus and atherosclerosis. [Review] [28 refs]. Bioessays 1995;17:899-903. 20. Shih JC,.Kelemen DW. Possible role of viruses in atherosclerosis. [Review] [57 refs]. Advances in Experimental Medicine & Biology 1995;369:89-98. 21. Melnick JL, Adam E, DeBakey ME. Cytomegalovirus and atherosclerosis. [Review] [45 refs]. European Heart Journal 1993;14 Suppl K:30-8. 22. Bruggeman CA,.Dam-Mieras MC. The possible role of cytomegalovirus in atherogenesis. [Review] [123 refs]. Progress in Medical Virology 1991;38:1-26. 23. Melnick JL, Adam E, DeBakey ME. Possible role of cytomegalovirus in atherogenesis. [Review] [20 refs]. JAMA 1990;263:2204-7. 101 24. Petrie BL, Adam E, Melnick JL. Association of herpesvirus/cytomegalovirus infections with human atherosclerosis. [Review] [82 refs]. Progress in Medical Virology 1988;35:21-42. 25. Wagner HR. Cardiac disease in congenital infections. [Review] [83 refs]. Clinics in Perinatology 1981;8:481-97. 26 Muhlestein JB. Chronic infection and coronary artery disease. [Review] [129 refs]. Medical Clinics of North America 2000;84:123-48. 27 Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000;20:52-63. 28 Schussheim AE,.Fuster V. Antibiotics for myocardial infarction? A possible role of infection in atherogenesis and acute coronary syndromes. [Review] [52 refs]. Drugs 1999;57:283-91. 29 Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? [see comments]. [Review] [62 refs]. Lancet 1997;350:430-6. 30. Gurfinkel EP,.Bozovich G. Emerging role of antibiotics in atherosclerosis. [Review] [21 refs]. American Heart Journal 1999;138:S537-S538. 31. Sorlie PD, Nieto FJ, Adam E, Folsom AR, Shahar E, Massing M. A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study. Archives of Internal Medicine 2000;160:2027-32. 32. Roivainen M, Viik-Kajander M, Palosuo T, Toivanen P, Leinonen M, Saikku et al. Infections, inflammation, and the risk of coronary heart disease. Circulation 2000;101:252-7. 33 Fagerberg B, Gnarpe J, Gnarpe H, Agewall S, Wikstrand J. Chlamydia pneumoniae but not cytomegalovirus antibodies are associated with future risk of stroke and cardiovascular disease: a prospective study in middle-aged to elderly men with treated hypertension. Stroke 1999;30:299-305. 34. Folsom AR, Nieto FJ, Sorlie P, Chambless LE, Graham DY. Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators. Circulation 1998;98:845-50. 35. Nieto FJ, Adam E, Sorlie P, Farzadegan H, Melnick JL, CoMStock GW et al. Cohort study of cytomegalovirus infection as a risk factor for carotid intimal-medial thickening, a measure of subclinical atherosclerosis [see comments]. Circulation 1996;94:922-7. 36. Ridker PM, Hennekens CH, Buring JE, Kundsin R, Shih J. Baseline IgG antibody titers to Chlamydia pneumoniae, Helicobacter pylori, herpes simplex virus, and cytomegalovirus and the risk for cardiovascular disease in women [see comments]. Annals of Internal Medicine 1999;131:573-7. 37. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999; 81:245-7. 102 38. Ossewaarde JM, Feskens EJ, de Vries A, Vallinga CE, Kromhout D. Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not. Epidemiology & Infection 1998;120:93-9. 39. Menschikowski M, Rosner-Schiering A, Eckey R, Mueller E, Koch R, Jaross et al. Expression of secretory group IIA phospholipase A(2) in relation to the presence of microbial agents, macrophage infiltrates, and transcripts of proinflammatory cytokines in human aortic tissues. Arteriosclerosis, Thrombosis & Vascular Biology 2000;20:751-62. 40. Wanishsawad C, Zhou YF, Epstein SE. Chlamydia pneumoniae-induced transactivation of the major immediate early promoter of cytomegalovirus: potential synergy of infectious agents in the pathogenesis of atherosclerosis. Journal of Infectious Diseases 2000;181:787-90. 41. Zhu J, Quyyumi AA, Norman JE, Csako G, Epstein SE. Cytomegalovirus in the pathogenesis of atherosclerosis: the role of inflammation as reflected by elevated C-reactive protein levels. Journal of the American College of Cardiology 1999;34:1738-43. 42. Hunter GC, Henderson AM, Westerband A, Kobayashi H, Suzuki F, Yan ZQ Et al. The contribution of inducible nitric oxide and cytomegalovirus to the stability of complex carotid plaque. Journal of Vascular Surgery 1999;30:36-49. 43. Speir E, Yu ZX, Ferrans VJ. Infectious agents in coronary artery disease: viral infection, aspirin, and gene expression in human coronary smooth muscle cells. [Review] [60 refs]. Revista Portuguesa de Cardiologia 1998;17 Suppl 2:II33-II39. 44. Anderson JL, Carlquist JF, Muhlestein JB, Horne BD, Elmer SP. Evaluation of C reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction. Journal of the American College of Cardiology 1998;32:35-41. 45. Arkonac B, Mauck KA, Chou S, Hosenpud JD. Low multiplicity cytomegalovirus infection of human aortic smooth muscle cells increases levels of major histocompatibility complex class I antigens and induces a proinflammatory cytokine milieu in the absence of cytopathology. Journal of Heart & Lung Transplantation 1997;16:1035-45. 46. Guetta E, Guetta V, Shibutani T, Epstein SE. Monocytes harboring cytomegalovirus: interactions with endothelial cells, smooth muscle cells, and oxidized low-density lipoprotein. Possible mechanisms for activating virus delivered by monocytes to sites of vascular injury. Circulation Research 1997;81:8-16. 47. Zhou YF, Guetta E, Yu ZX, Finkel T, Epstein SE. Human cytomegalovirus increases modified low density lipoprotein uptake and scavenger receptor mRNA expression in vascular smooth muscle cells. Journal of Clinical Investigation 1996;98:2129-38. 48. Datta SK, Tumilowicz JJ, Trentin JJ. Lysis of human arterial smooth muscle cells infected with herpesviridae by peripheral blood mononuclear cells: implications for atherosclerosis. Viral Immunology 1993;6:153-60. 49. Span AH, Dam-Mieras MC, Mullers W, Endert J, Muller AD, Bruggeman et al. The effect of virus infection on the adherence of leukocytes or platelets to endothelial cells. European Journal of Clinical Investigation 1991;21:331-8. 103 50. Hendrix MG, Daemen M, Bruggeman CA. Cytomegalovirus nucleic acid distribution within the human vascular tree. American Journal of Pathology 1991;138:563-7. 51. Span AH, van Boven CP, Bruggeman CA. The effect of cytomegalovirus infection on the adherence of polymorphonuclear leucocytes to endothelial cells. European Journal of ClinicaL Investigation 1989;19:542-8. 52 Colizzi C, Rizzello V, Angiolillo DJ, Liuzzo G, Ginnetti F, Monaco C et al. In vitro hyperreactivity to lipopolysaccharide in patients with history of unstable angina is not associated with seropositivity for Cytomegalovirus, Helicobacter pylori and Chlamydia pneumoniae. Cardiologia 1999;44:377-80 53. Yonemitsu Y, Nakagawa K, Tanaka S, Mori R, Sugimachi K, Sueishi K. In situ detection of frequent and active infection of human cytomegalovirus in inflammatory abdominal aortic aneurysMS: possible pathogenic role in sustained chronic inflammatory reaction. Laboratory Investigation 1996;74:723-36. 54. Ammann P, Marschall S, Kraus M, Schmid L, Angehrn W, Krapf R et al. Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest 2000;117:333-8. 55. Rothenbacher D, Hoffmeister A, Bode G, Wanner P, Koenig W, Brenner H. Cytomegalovirus infection and coronary heart disease: results of a german case-control study. Journal of Infectious Diseases 1999;179:690-2. 56. Adler SP, Hur JK, Wang JB, Vetrovec GW. Prior infection with cytomegalovirus is not a major risk factor for angiographically demonstrated coronary artery atherosclerosis. Journal of Infectious Diseases 1998;177:209-12. 57. Sorlie PD, Adam E, Melnick SL, Folsom A, Skelton T, Chambless LE et al. Cytomegalovirus/herpesvirus and carotid atherosclerosis: the ARIC Study. Journal of Medical Virology 1994;42:33-7. 58. Musiani M, Zerbini ML, Muscari A, Puddu GM, Gentilomi G, Gibellini D et al. Antibody patterns against cytomegalovirus and Epstein-Barr virus in human atherosclerosis. Microbiologica 1990;13:35-41. 59 Kaftan HA, Kaftan O, Kilic M. Markers of chronic infection and inflammation. Are they important in cases with chronic coronary heart disease. Japanese Heart Journal 1999;40:275-80. 60 Adam E, Melnick JL, Probtsfield JL, Petrie BL, Burek J, Bailey KR et al. High levels of cytomegalovirus antibody in patients requiring vascular surgery for atherosclerosis. Lancet 1987;2:291-3. 61 Horvath R, Cerny J, Benedik J, Jr., Hokl J, Jelinkova I, Benedik J. The possible role of human cytomegalovirus (HCMV) in the origin of atherosclerosis. Journal of Clinical Virology 2000;16:17-24. 62. Chiu B, Viira E, Tucker W, Fong IW. Chlamydia pneumoniae, cytomegalovirus, and herpes simplex virus in atherosclerosis of the carotid artery. Circulation 1997;96:2144-8. 104 63. Pauletto P, Pisoni G, Boschetto R, Zoleo M, Pessina AC, Palu G. Human cytomegalovirus and restenosis of the internal carotid artery [see comments]. Stroke 1996;27:1669-71. 64. Kuo CC, Grayston JT, Campbell LA, Goo YA, Wissler RW, Benditt EP. Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old). Proceedings of the National Academy of Sciences of the United States of America 1995;92:6911-4. 65. Hendrix MG, Dormans PH, Kitslaar P, Bosman F, Bruggeman CA. The presence of cytomegalovirus nucleic acids in arterial walls of atherosclerotic and nonatherosclerotic patients. American Journal of Pathology 1989;134:1151-7. 66 Benditt EP, Barrett T, McDougall JK. Viruses in the etiology of atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America 1983;80:6386-9. 67 Melnick JL, Petrie BL, Dreesman GR, Burek J, McCollum CH, DeBakey ME. Cytomegalovirus antigen within human arterial smooth muscle cells. Lancet 1983;2:644-7. 68. Chiu B. Multiple infections in carotid atherosclerotic plaques. American Heart Journal 1999;138:S534-S536. 69. Dummer S, Lee A, Breinig MK, Kormos R, Ho M, Griffith B. Investigation of cytomegalovirus infection as a risk factor for coronary atherosclerosis in the explanted hearts of patients undergoing heart transplantation. Journal of Medical Virology 1994;44:305-9. 70. Melnick JL, Hu C, Burek J, Adam E, DeBakey ME. Cytomegalovirus DNA in arterial walls of patients with atherosclerosis. Journal of Medical Virology 1994;42:170-4. 71. Hendrix MG, Salimans MM, van Boven CP, Bruggeman CA. High revalence of latently present cytomegalovirus in arterial walls of patients suffering from grade III atherosclerosis. American Journal of Pathology 1990;136:23-8. 72. Lindberg G, Rastam L, Lundblad A, Sorlie PD, Folsom AR. The association between serum sialic acid and asymptomatic carotid atherosclerosis is not related to antibodies to herpes type viruses or Chlamydia pneumoniae. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. International Journal of Epidemiology 1997;26:1386-91. 73. Nieto FJ, Sorlie P, CoMStock GW, Wu K, Adam E, Melnick JL et al. Cytomegalovirus infection, lipoprotein(a), and hypercoagulability: an atherogenic link? Arteriosclerosis, Thrombosis & Vascular Biology 1997;17:1780-5. 74 Danesh J, Wong Y, Ward M, Muir J. Risk factors for coronary heart disease and persistent infection with Chlamydia pneumoniae or cytomegalovirus: a population-based study. Journal of Cardiovascular Risk 1999;6:387-90. 75. Nieto FJ, Szklo M, Sorlie PD. Cytomegalovirus infection and coronary heart disease [letter; comment]. Circulation 1999;100:e139. 76. Blum A. Anti-CMV antibodies and coronary artery disease [letter; comment]. Circulation 1999;100:e138. 77. Cheng TO. Atherosclerosis is not an infectious process [letter; comment]. Cardiology 1999;91:73. 105 78. Bosch X. Mechanism for putative link between atherosclerosis and viruses found [news]. Lancet 1999;354:1976. 79. Plotkin SA. Conclusions. American Heart Journal 1999;138:S560. 80. Hodinka RL. Designing studies to confirm a link between viral infection and atherosclerosis. [Review] [8 refs]. American Heart Journal 1999;138:S554-S555. 81. Vercellotti G. Infectious agents that play a role in atherosclerosis and vasculopathies. What are they? What do we do about them? Canadian Journal of Cardiology 1999;15 Suppl B:13B-5B. 82. Gura T. Infections: a cause of artery-clogging plaques? [news] [published erratum appears in Science 1998 aug 14;281(5379):923]. Science 1998;281:35. 83. Satta J, Mosorin M, Paakko P, Juvonen T. Regarding "Detection of active cytomegalovirus infection in inflammatory aortic aneurysMS with RNA polymerase chain reaction" [letter; comment] [see comments]. Journal of Vascular Surgery 1998;27:587-8. 84. Constans J, Seigneur M, Blann A, Conri C. Chronic infections and coronary heart disease [letter; comment]. Lancet 1997;350:1030. 85. Ailani RK, SimMS R, Caracioni AA, West BC. Extensive mesenteric inflammatory veno-occlusive disease of unknown etiology after primary cytomegalovirus infection: first case. American Journal of Gastroenterology 1997;92:1216-8. 86. Numazaki K,.Chiba S. Cytomegalovirus infection and restenosis [letter; comment]. Stroke 1997;28:1088-90. 87. Buja LM. Does atherosclerosis have an infectious etiology? [editorial; comment]. Circulation 1996;94:872-3. 88. Stehbens WE. Coronary artery disease in cardiac transplant recipients [letter; comment]. Medical Journal of Australia 1996;164:254-5. 89. Sutter MC. Lessons for atherosclerosis research from tuberculosis and peptic ulcer [editorial]. CMAJ 1995;152:667-70. 90. Kubo S, Kishino T, Satake N, Okano M, Mikawa M, Ishikawa N. A neonatal case of hydranencephaly caused by atheromatous plaque obstruction of aortic arch: possible association with a congenital cytomegalovirus infection? Journal of Perinatology 1994;14:483-6. 91. Aguado S, Gorostidi M, Gomez E, Gago E, Sanchez L, Ona M et al. Cytomegalovirus (CMV) infection complicated with renal arterial thrombosis. Rapid diagnosis of CMV infection. Clinical Transplants 1989;300-1. 92. Cour MI, Lopez de Atalaya FJ, Palau L, Fernandez CE, Perezagua, C. Lack of serological association between herpesvirus and atherosclerosis [letter]. Lancet 1989;1:279. 93. Haines A, Peckham C, Imeson J, Singh M. Cytomegalovirus and atherosclerosis [letter]. Lancet 1988;1:990-1. 94. Digre KB, Blodi CF, Bale JF. Cytomegalovirus infection in a healthy adult associated with recurrent branch retinal artery occlusion. Retina 1987;7:230-2. 106 95. Petrie BL, Melnick JL, Adam E, Burek J, McCollum CH, DeBakey ME. Nucleic acid sequences of cytomegalovirus in cells cultured from human arterial tissue [letter]. Journal of Infectious Diseases 1987;155:158-9. 96. Smith MS, Venter PC, de Wet JI. Cytomegalovirus and atherosclerosis [letter]. South African Medical Journal 1984;65:793. Cytomegalovirus and Coronary Heart Disease - additional papers from herpes medline search 1. Fong IW. Emerging relations between infectious diseases and coronary artery disease and atherosclerosis. [Review] [95 refs]. CMAJ 2000;163:49-56. 2. Muhlestein JB. Chronic infection and coronary artery disease. [Review] [129 refs]. Medical Clinics of North America 2000;84:123-48. 3. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000;20:52-63. 4. Lozinguez O, Arnaud E, Velut JG, Tiev KP, Fiessinger JN, Emmerich J. [Cytomegalovirus and arterial disease. Current aspects]. [Review] [60 refs] [French]. Archives des Maladies du Coeur et des Vaisseaux 1999;92:1205-12. 5. Pandey JP,.LeRoy EC. Human cytomegalovirus and the vasculopathies of autoimmune diseases (especially scleroderma), allograft rejection, and coronary restenosis. [Review] [44 refs]. Arthritis & Rheumatism 1998;41:10-5. 6. Libby P, Egan D, Skarlatos S. Roles of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. [Review] [91 refs]. Circulation 1997;96:4095-103. 7. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? [see comments]. [Review] [62 refs]. Lancet 1997;350:430-6. 8. Epstein SE, Speir E, Zhou YF, Guetta E, Leon M, Finkel T. The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus. [Review] [31 refs]. Lancet 1996;348 Suppl 1:s13-s17. 9. Carlsson J, Miketic S, Brom J, Ross R, Bachmann H, Tebbe U. Prior cytomegalovirus, Chlamydia pneumoniae or Helicobacter pylori infection and the risk of restenosis after percutaneous transluminal coronary angioplasty. International Journal of Cardiology 2000;73:165-71. 10. Danesh J, Wong Y, Ward M, Muir J. Risk factors for coronary heart disease and persistent infection with Chlamydia pneumoniae or cytomegalovirus: a population-based study. Journal of Cardiovascular Risk 1999;6:387-90. 11 Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae or cytomegalovirus: population-based study of coronary heart disease. Heart 1999;81:245-7. 107 12 . Daus H, Ozbek C, Saage D, Scheller B, Schieffer H, Pfreundschuh M et al. Lack of evidence for a pathogenic role of Chlamydia pneumoniae and cytomegalovirus infection in coronary atheroma formation [see comments]. Cardiology 1998;90:83-8. 13. Speir E, Huang ES, Modali R, Leon MB, Shawl F, Finkel T et al. Interaction of human cytomegalovirus with p53: possible role in coronary restenosis. Scandinavian Journal of Infectious Diseases - Supplementum 1995;99:78-81. 14. Speir E, Modali R, Huang ES, Leon MB, Shawl F, Finkel T et al. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis [see comments]. Science 1994;265:391-4. 15. Marx J. CMV-p53 interaction may help explain clogged arteries [news; comment]. Science 1994;265:320. 16. Kaftan HA, Kaftan O, Kilic M. Markers of chronic infection and inflammation. Are they important in cases with chronic coronary heart disease. Japanese Heart Journal 1999;40:275-80. 17. Colizzi C, Rizzello V, Angiolillo DJ, Liuzzo G, Ginnetti F, Monaco C et al. In vitro hyperreactivity to lipopolysaccharide in patients with history of unstable angina is not associated with seropositivity for Cytomegalovirus, Helicobacter pylori and Chlamydia pneumoniae. Cardiologia 1999;44:377-80. 18. Blum A, Giladi M, Weinberg M, Kaplan G, Pasternack H, Laniado S et al. High anti cytomegalovirus (CMV) IgG antibody titer is associated with coronary artery disease and may predict post-coronary balloon angioplasty restenosis. American Journal of Cardiology 1998;81:866-8. 19. Ossewaarde JM, Feskens EJ, De Vries A, Vallinga CE, Kromhout D. Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not. Epidemiology & Infection 1998;120:93-9. 20. Bertrand ME,.Bauters C. Cytomegalovirus infection and coronary restenosis [editorial; comment]. Circulation 1999;99:1278-9. 21. Stiegler H, Kolbe-Busch S, Fischer Y, Leschke M, Reinauer H. Antibodies to cytomegalovirus or Chlamydia pneumoniae and coronary heart disease [letter]. Lancet 1998;351:143. 22. Taylor-Robinson D,.Thomas BJ. Antibodies to cytomegalovirus or Chlamydia pneumoniae and coronary heart disease [letter; comment]. Lancet 1998;351:142. 23. Carlsson J, Miketic S, Mueller KH, Brom J, Ross R, von Essen R et al. Previous cytomegalovirus or Chlamydia pneumoniae infection and risk of restenosis after percutaneous transluminal coronary angioplasty [letter] [see comments]. Lancet 1997;350:1225. 24. Holzman DC. Cytomegalovirus and restenosis [news]. Molecular Medicine Today 1996;2:270. 25. Powell KR. Postanginal sepsis following infectious mononucleosis [letter]. Reviews of Infectious Diseases10:1229-Dec. 108 Cytomegalovirus and Coronary Heart Disease – science citation index search 1 Bartels C, Maass M, Bein G, Brill N, Bechtel JFM, Leyh R et al. Association of serology with the endovascular presence of Chlamydia pneumoniae anti cytomegalovirus in coronary artery and vein graft disease. Circulation 2000;101:137-41. 2 Coles KA, Plant AJ, Riley TV, Smith DW. Cardiovascular disease: an infectious aetiology? Reviews In Medical Microbiology 1998;9:17-27. 3 Field AK. Human cytomegalovirus: challenges opportunities and new drug development. Antiviral Chemistry & Chemotherapy 1999;10:219-32. 4 Koskinen P, LeMStrom K, Bruggeman C, Lautenschlager I, Hayry P. Acute Cytomegalovirus-infection induces a subendothelial inflammation (endothelialitis) in the allograft vascular wall - a possible linkage with ehhanced allograft arteriosclerosis. American Journal Of Pathology 1994;144:41-50. 5 Kroger K, Buss C, Renzing-Kohler K, Santosa F, Rudofsky G. Segmental manifestation of peripheral atherosclerosis and its association to risk factors. Vasa-Journal Of Vascular Diseases 2000;29:199-203. 6 Mayr M, Kiechl S, Willeit J, Wick G, Xu QB. Infections, immunity, and atherosclerosis - Associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosis. Circulation 2000;102:833-9. 7 Mehta JL,.Romeo F. Inflammation, infection and atherosclerosis - Do antibacterials have a role in the therapy of coronary artery disease? Drugs 2000;59:159-70. 8 Nieto FJ, Adam E, Sorlie PD, Farzadegan H, Melnick JL, CoMStock GW et al. A Propspective-study of cytomegalovirus and other Herpes viruses as predictors of subclinical atherosclerosis. American Journal Of Epidemiology 1995;141:S83-S83. 9 Nieto FJ. Viruses and atherosclerosis: A critical review of the epidemiologic evidence. American Heart Journal 1999;138:S453-S460. 10 Pauletto P, Pisoni G, Boschetto R, Zoleo M, Pessina AC, Palu G. Human cytomegalovirus and restenosis of the internal carotid artery. Stroke 1996;27:1669-71. 11 Ridker PM, Hennekens CH, Stampfer MJ, Wang F. Prospective study of herpes simplex virus, cytomegalovirus, and the risk of future myocardial infarction and stroke. Circulation 1998;98:2796-9. 12 Span AHM, Grauls G, Bosman F, Vanboven CPA, Bruggeman CA. Cytomegalovirus-infection induces vascular injury in the rat. Atherosclerosis 1992;93:41-52. 13 Strachan DP, Carrington D, Mendall MA, Butland BK, Sweetnam PM, Elwood PC. Cytomegalovirus seropositivity and incident ischaemic heart disease in the Caerphilly prospective heart disease study. Heart 1999;81:248-51. 14 Tanaka S, Toh Y, Mori R, Komori K, Okadome K, Sugimachi K. Possible role of Cytomegalovirus in the pathogenesis of inflammatory aortic diseases - A preliminary-report. Journal Of Vascular Surgery 1992;16:274-9. 109 15 Vercellotti GM. Potential role of viruses in thrombosis and atherosclerosis. Trends In Cardiovascular Medicine 1995;5:128-33. 16 Visseren FLJ, Bouter KP, Pon MJ, Hoekstra JBL, Erkelens DW, Diepersloot RJA. Patients with diabetes mellitus and atherosclerosis; A role for cytomegalovirus? Diabetes Research And Clinical Practice 1997;36:49-55. 17 Wattre P, Dewilde A, Lobert PE. Human cytomegalovirus pathogenesis - an overview. Revue De Medecine Interne 1995;16:354-67. 18 Yonemitsu Y, Kaneda Y, Komori K, Hirai K, Sugimachi K, Sueishi K. The immediate early gene of human cytomegalovirus stimulates vascular smooth muscle cell proliferation in vitro and in vivo. Biochemical And Biophysical Research Communications 1997;231 :447-51. 19 Bayad J, Galteau MM, Siest G. Viral theory of atherosclerosis - Possible role of Cytomegalovirus. Annales De Biologie Clinique 1993;51:101-7. 20 Chiu B, Viira E, Tucker W, Fong IW. Chlamydia pneumoniae, cytomegalovirus, and herpes simplex virus in atherosclerosis of the carotid artery. Circulation 1997;96:2144-8. 21 Epstein SE, Zhu JH, Burnett MS, Zhou YF, Vercellotti G, Hajjar D. Infection and atherosclerosis - Potential roles of pathogen burden and molecular mimicry. Arteriosclerosis Thrombosis And Vascular Biology 2000;20:1417-20. 22 Herzum M, Schaefer JR, Hufnagel G, Maisch B. Cytomegalo- and herpesvirus in pathogenesis and progression of native atherosclerosis and of re-stenosis after intervention. Herz 1998;23:193-6. 23 Horvath R, Cerny J, Benedik J, Hokl J, Jelinkova I. The possible role of human cytomegalovirus (HCMV) in the origin of atherosclerosis. Journal Of Clinical Virology 2000;16:17-24. 24 Melnick JL, Adam E, Debakey ME. Cytomegalovirus and atherosclerosis. Bioessays 1995;17:899-903. 25 Morre SA, Stooker W, Lagrand WK, van den Brule AJC, Niessen HWM. Microorganisms in the aetiology of atherosclerosis. Journal Of Clinical Pathology 2000;53:647-54. 26 Paz M, de Otero J, Codinach P, Ferrer-Ruscalleda F, Ibernon MGYM. Infection and coronary atherosclerosis: The role of Chlamydia pneumoniae. Revista Espanola De Cardiologia 1998;51:857-63. 27 Schonian U,.Maisch B. Cytomegalovirus associated diseases of the heart. Herz 1992;17:85-90. 28 Sorlie PD, Adam E, Melnick SL, Folsom A, Skelton T, Chambless LE et al. Cytomegalovirus Herpesvirus and acrotid atherosclerosis - The ARIC study. Journal Of Medical Virology 1994;42:33-7. 29 Sorlie PD, Nieto FJ, Adam E, Folsom AR, Shahar E, Massing M. A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease - The Atherosclerosis Risk in Communities (ARIC) Study. Archives Of Internal Medicine 2000;160:2027-32. 110 CYTOMEGALOVIRUS AND CHRONIC FATIGUE SYNDROME Cytomegalovirus and Chronic Fatigue Syndrome – medline search 1. Hana I, Vrubel J, Pekarek J, Cech K. The influence of age on transfer factor treatment of cellular immunodeficiency, chronic fatigue syndrome and/or chronic viral infections. Biotherapy 1996;9:91-5. 2. Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50:25-30. 3. study Carter BD, Edwards JF, Kronenberger WG, Michalczyk L, Marshall GS. Case control of chronic fatigue in pediatric patients. Pediatrics 1995;95:179-86. 4. Wallace HL, Natelson B, Gause W, Hay J. Human herpesviruses in chronic fatigue syndrome. Clinical & Diagnostic Laboratory Immunology 1999;6:216-23. 5. Wray BB, Gaughf C, Chandler FW, Jr., Berry SS, Latham JE, Wood L et al. Detection of Epstein-Barr virus and cytomegalovirus in patients with chronic fatigue. Annals of Allergy 1993;71:223-6. 6. Martin WJ. Stealth adaptation of an African green monkey simian cytomegalovirus. Experimental & Molecular Pathology 1999;66:3-7. 7. Martin WJ. Detection of RNA sequences in cultures of a stealth virus isolated from the cerebrospinal fluid of a healthcare worker with chronic fatigue syndrome. Case report. Pathobiology 1997;65:57-60. 8. like Martin WJ. Severe stealth virus encephalopathy following chronic-fatigue-syndromeillness: clinical and histopathological features. Pathobiology 1996;64:1-8. 9. Martin WJ,.Glass RT. Acute encephalopathy induced in cats with a stealth virus isolated from a patient with chronic fatigue syndrome. Pathobiology 1995;63:115-8. 10. Martin WJ, Zeng LC, Ahmed K, Roy M. Cytomegalovirus-related sequence in an atypical cytopathic virus repeatedly isolated from a patient with chronic fatigue syndrome. American Journal of Pathology 1994;145:440-51. CYTOMEGALOVIRUS AND GENERAL CHRONIC DISEASE Cytomegalovirus and General Chronic Disease – medline search 1. Farrell H, Degli-Esposti M, Densley E, Cretney E, Smyth M, Davis P et al. Cytomegalovirus MHC class I homologues and natural killer cells: an overview. [Review] [93 refs]. Microbes & Infection 2000;2:521-32. 2. Sweet C. The pathogenicity of cytomegalovirus. [Review] [265 refs]. FEMS Microbiology Reviews 1999;23:457-82. 3. Wiertz E, Hill A, Tortorella D, Ploegh H. Cytomegaloviruses use multiple mechanisms to elude the host immune response. [Review] [24 refs]. Immunology Letters 1997;57:213-6. 111 4. Huber BT, Hsu PN, Sutkowski N. Virus-encoded superantigens. [Review] [91 refs]. Microbiological Reviews 1996;60:473-82. 5 Tien RD, Felsberg GJ, Osumi AK. Herpesvirus infections of the CNS: MR findings. [Review] [103 refs]. AJR 1993; American Journal of Roentgenology. 161:167-76. 6. Caserta MT,.Hall CB. Human herpesvirus-6. [Review] [42 refs]. Annual Review of Medicine 1993;44:377-83. 7. Krueger GR,.Ramon A. Overview of immunopathology of chronic active herpesvirus infection. [Review] [43 refs]. Journal of Virological Methods 1988;21:11-8. 8. Stagno S, Pass RF, Dworsky ME, Britt WJ, Alford CA. Congenital and perinatal cytomegalovirus infections: clinical characteristics and pathogenic factors. [Review] [42 refs]. Birth Defects: Original Article Series 1984;20:65-85. 9. Jordan MC. Latent infection and the elusive cytomegalovirus. [Review] [95 refs]. Reviews of Infectious Diseases 1983;5:205-15. 10. Duchowny M, Caplan L, Siber G. Cytomegalovirus infection of the adult nervous system. Annals of Neurology 1979;5:458-61. 11. Kumar ML,.Nankervis GA. Cytomegalovirus infections. [Review] [74 refs]. Southern Medical Journal 1979;72:854-61. 12. Jack I. Persistent infections with herpesviruses. [Review] [77 refs]. Progress in Medical Virology 1974;18:160-77. 13. Roth EM,.WilliaMS RC, Jr. Viral-host relationships in chronic diseases of man. Journal of Chronic Diseases 1973;26:55-61. 14. Stern H. Cytomegalovirus: a cause of persistent latent infection. [Review] [49 refs]. Journal of Clinical Pathology - Supplement (Royal College of Pathologists) 1972;6:34-8. 15. Chang TW. Recurrent viral infection (reinfection). [Review] [109 refs]. New England Journal of Medicine 1971;284:765-73. 16. Onno M, Pangault C, Le Friec G, Guilloux V, Andre P, Fauchet R. Modulation of HLA-G antigens expression by human cytomegalovirus: specific induction in activated macrophages harboring human cytomegalovirus infection. Journal of Immunology 2000;164:6426-34. 17. Slobedman B,.Mocarski ES. Quantitative analysis of latent human cytomegalovirus. Journal of Virology 1999;73:4806-12. 18. Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arteriosclerosis, Thrombosis & Vascular Biology 1999;19:972-8. 112 19. Scotet E, Peyrat MA, Saulquin X, Retiere C, Couedel C, Davodeau F et al. Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes. European Journal of Immunology 1999;29:973-85. 20. Soderberg-Naucler C, Fish KN, Nelson JA. Growth of human cytomegalovirus in primary macrophages. Methods 1998;16:126-38. 21. Montgomery EA, Devaney KO, Giordano TJ, Weiss SW. Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells: a distinctive lesion with features simulating inflammatory conditions, Hodgkin's disease, and various sarcomas. Modern Pathology 1998;11:384-91. 22. Satta J, Laurila A, Paakko P, Haukipuro K, Sormunen R, Parkkila S et al. Chronic inflammation and elastin degradation in abdominal aortic aneurysm disease: an immunohistochemical and electron microscopic study. European Journal of Vascular & Endovascular Surgery 1998;15:313-9. 23. Hahn G, Jores R, Mocarski ES. Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells. Proceedings of the National Academy of Sciences of the United States of America 1998;95:3937-42. 24. Larcher C, Recheis H, Sgonc R, Gottinger W, Huemer HP, Irschick EU. Influence of viral infection on expression of cell surface antigens in human retinal pigment epithelial cells. Graefes Archive for Clinical & Experimental Ophthalmology 1997;235:709-16. 25. Gebert S, Schmolke S, Sorg G, Floss S, Plachter B, Stamminger T. The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication. Journal of Virology 1997;71:7048-60. 26. Farrell HE, Vally H, Lynch DM, Fleming P, Shellam GR, Scalzo AA et al. Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo [see comments]. Nature 1997;386:510-4. 27. Wills MR, Carmichael AJ, Mynard K, Jin X, Weekes MP, Plachter B et al. The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL. Journal of Virology 1996;70:7569-79. 28. Gilbert MJ, Riddell SR, Plachter B, Greenberg PD. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Nature 1996;383:720-2. 29. Huber BT, Hsu PN, Sutkowski N. Virus-encoded superantigens. [Review] [91 refs]. Microbiological Reviews 1996;60:473-82. 30. Kondo K, Xu J, Mocarski ES. Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proceedings of the National Academy of Sciences of the United States of America 1996;93:11137-42. 113 31 Toth FD, Aboagye-Mathiesen G, Szabo J, Liu X, Mosborg-Petersen P, Kiss et al. Bidirectional enhancing activities between human T cell leukemia-lymphoma virus type I and human cytomegalovirus in human term syncytiotrophoblast cells cultured in vitro. AIDS Research & Human Retroviruses 1995;11:1495-507. 32 Oleszak EL. Molecular mimicry between Fc receptors and viral antigens. [Review] [53 refs]. Archivum Immunologiae et Therapiae Experimentalis 1994;42:83-8. 33 Wolff D, Sinzger C, Drescher P, Jahn G, Plachter B. Reduced levels of IE2 gene expression and shutdown of early and late viral genes during latent infection of the glioblastoma cell line U138-MG with selectable recombinants of human cytomegalovirus. Virology 1994;204:101-13. 34. Fukuda S, Furuta Y, Takasu T, Suzuki S, Inuyama Y, Nagashima K. The significance of herpes viral latency in the spiral ganglia. Acta Oto-Laryngologica - Supplement 1994;514:108-10. 35. Kline JN, Geist LJ, Monick MM, Stinski MF, Hunninghake GW. Regulation of expression of the IL-1 receptor antagonist (IL-1ra) gene by products of the human cytomegalovirus immediate early genes. Journal of Immunology 1994;152:2351-7. 36. Numazaki K, Nagata N, Sato T, Chiba S. Effect of glycyrrhizin, cyclosporin A, and tumor necrosis factor alpha on infection of U-937 and MRC-5 cells by human cytomegalovirus. Journal of Leukocyte Biology 1994;55:24-8. 37. Reddehase MJ, Balthesen M, Rapp M, Jonjic S, Pavic I, Koszinowski UH. The conditions of primary infection define the load of latent viral genome in organs and the risk of recurrent cytomegalovirus disease. Journal of Experimental Medicine 1994;179:185-93. 38. Liu B, Hermiston TW, Stinski MF. A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2. Journal of Virology 1991;65:897-903. 39. Kari B,.Gehrz R. Analysis of human antibody responses to human cytomegalovirus envelope glycoproteins found in two families of disulfide linked glycoprotein complexes designated gC-I and gC-II. Archives of Virology 1990;114:213-28. 40. Manor E,.Sarov I. Inhibition of CMV replication in human fibroblasts by human monocyte-derived macrophages: implication for CMV persistent infection. Microbial Pathogenesis 1988;5:97-107. 41. Tanaka J, Ogura T, Sato H, Hatano M. Establishment and biological characterization of an in vitro human cytomegalovirus latency model. Virology 1987;161:62-72. 42. Ogura T, Tanaka J, Kamiya S, Sato H, Ogura H, Hatano M. Human cytomegalovirus persistent infection in a human central nervous system cell line: production of a variant virus with different growth characteristics. Journal of General Virology 1986;67 :2605-16. 43. Furukawa T. A variant of human cytomegalovirus derived from a persistently infected culture. Virology 1984;137:191-4. 44. Hung T, Mummaw JG, Wigdahl BL, Fang ZY, Huaying J, Rapp F. Ultrastructural changes during herpes simplex virus type 2 latency and reactivation in vitro. Intervirology 1984;21:5-16. 114 45. Fiorilli M, Sirianni MC, Iannetti P, Pana A, Divizia M, Aiuti F. Cell-mediated immunity in human cytomegalovirus infection. Infection & Immunity 1982;35:1162-4. 46. Furukawa T. Cell cycle-dependent chronic infection of human cytomegalovirus in human osteogenic sarcoma cells. Journal of General Virology 1979;45:81-8. 47. Geder L, Ladda RL, Kreider JW, Sanford EJ, Rapp F. Properties of human epithelioid cells established in vitro by a herpesvirus [IBRV(HMC)] isolated from cytomegalovirus transformed human cells. Journal of the National Cancer Institute 1979;63:1313-21. 48. Furukawa T, Yoshimura N, Jean JH, Plotkin SA. Chronically persistent infection with human cytomegalovirus in human lymphoblasts. Journal of Infectious Diseases 1979;139:211-4. 49. Furukawa T. Persistent infection with human cytomegalovirus in a lymphoblastoid cell line. Virology 1979;94:214-8. 50. Boldogh I, Gonczol E, Gartner L, Vaczi L, Michelson S. Latent infection of mouse cells with human cytomegalovirus. Bulletin du Cancer 1976;63:411-6. 51. Geder KM, Lausch R, O'Neill F, Rapp F. Oncogenic transformation of human embryo lung cells by human cytomegalovirus. Science 1976;192:1134-7. 52. Uddhammar A, Boman J, Juto P, Rantapaa DS. Antibodies against Chlamydia pneumoniae, cytomegalovirus, enteroviruses and respiratory syncytial virus in patients with polymyalgia rheumatica. Clinical & Experimental Rheumatology 1997;15:299-302. 53. Mintz L, Drew WL, Miner RC, Braff EH. Cytomegalovirus infections in homosexual men. An epidemiological study. Annals of Internal Medicine 1983;99:326-9. 54. Nowak TV, Goddard M, Batteiger B, Cummings OW. Evolution of acute cytomegalovirus gastritis to chronic gastrointestinal dysmotility in a nonimmunocompromised adult. Gastroenterology 1999;116:953-8. 55. Hirabayashi S, Shiobara J, Iwasaki Y, Ogiso Y, Kubota N, Oka A et al. Chronic meningoencephalitis due to cytomegalovirus infection in a nonimmunocompromised patient: an autopsy case. Journal of Child Neurology 1998;13:570-3. 56. Colsky AS, Jegasothy SM, Leonardi C, Kirsner RS, Kerdel FA. Diagnosis and treatment of a case of cutaneous cytomegalovirus infection with a dramatic clinical presentation. [Review] [21 refs]. Journal of the American Academy of Dermatology 1998;38:349-51. 57. Jay V, Otsubo H, Hwang P, Hoffman HJ, Blaser S, Zielenska M. Coexistence of hemimegalencephaly and chronic encephalitis. Detection of cytomegalovirus by the polymerase chain reaction. Childs Nervous System 1997;13:35-41. 58. Suzumura H, Sakurai K, Kano K, Ichimura T. Chronic respiratory failure after acquired cytomegalovirus infection in a very low birthweight infant. Acta Paediatrica Japonica 1996;38:677-80. 59. Faure C, Besnard M, Hirsch A, Mougenot JF, Peuchmaur M, Cezard JP et al. Chronic hypertrophic gastropathy in a child resembling adult Menetrier's disease. Journal of Pediatric Gastroenterology & Nutrition 1996;23:419-21. 115 60. Zuschke CA, Herrera JL, Pettyjohn FS. Cytomegalovirus hepatitis mimicking an acute exacerbation of chronic hepatitis B. Southern Medical Journal 1996;89:1213-6. 61. Shen CY, Chang SF, Yang SL, Huang ES, Wu CW. Urinary cytomegalovirus shedding profile in children with subclinical infection [letter] [published erratum appears in Lancet 1994 Jan 1;343(8888):64]. Lancet 1993;342:1432. 62. Rubenstein E. Lifelong viral infections. Medical Section Proceedings 1988;97-106. 63. Chronic fatigue possibly related to Epstein-Barr virus--Nevada. MMWR - Morbidity & Mortality Weekly Report 1986;35:350-2 chronic fatigue. 64. Markowitz PI. Autism in a child with congenital cytomegalovirus infection. Journal of Autism & Developmental Disorders 1983;13:249-53. 65. Craighead JE. Persistent viral infections of man. Monographs in Pathology 1982; 138-55. 66 More about cytomegalovirus infection. Medical Journal of Australia 1971;1:111-2. 67. Hirabayashi S, Shiobara J, Iwasaki Y, Ogiso Y, Kubota N, Oka A et al. Chronic meningoencephalitis due to cytomegalovirus infection in a nonimmunocompromised patient: an autopsy case. Journal of Child Neurology 1998;13:570-3. 68. Uddhammar A, Boman J, Juto P, Rantapaa DS. Antibodies against Chlamydia pneumoniae, cytomegalovirus, enteroviruses and respiratory syncytial virus in patients with polymyalgia rheumatica. Clinical & Experimental Rheumatology 1997;15:299-302. 69. Jay V, Otsubo H, Hwang P, Hoffman HJ, Blaser S, Zielenska M. Coexistence of hemimegalencephaly and chronic encephalitis. Detection of cytomegalovirus by the polymerase chain reaction. Childs Nervous System 1997;13:35-41. 70. Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50:25-30. Chronic fatigue 71. Jay V,.Becker LE. Surgical pathology of epilepsy resections in childhood. [Review] [64 refs]. Seminars in Pediatric Neurology 1995;2:227-36. 72. Leimola-Virtanen R, Happonen RP, Syrjanen S. Cytomegalovirus (CMV) and Helicobacter pylori (HP) found in oral mucosal ulcers. Journal of Oral Pathology & Medicine 1995;24:14-7. 73. Sierra-Honigmann AM, Carbone KM, Yolken RH. Polymerase chain reaction (PCR) search for viral nucleic acid sequences in schizophrenia. British Journal of Psychiatry 1995;166:55-60. 74. Loftus EV, Jr., Alexander GL, Carpenter HA. Cytomegalovirus as an exacerbating factor in ulcerative colitis. Journal of Clinical Gastroenterology 1994;19:306-9. 75. Nakamura Y, Sakuma S, Ohta Y, Kawano K, Hashimoto T. Detection of the human cytomegalovirus gene in placental chronic villitis by polymerase chain reaction. Human Pathology 1994;25:815-8. 116 76. Teng RJ, Chen RL, Lin DT, Lin KH, Lee CY. Cytomegalovirus-induced persistent mononucleosis in an infant. Chung-Hua Min Kuo Hsiao Erh Ko i Hsueh Hui Tsa Chih 1994;35:221-4. 77. Vinters HV, Wang R, Wiley CA. Herpesviruses in chronic encephalitis associated with intractable childhood epilepsy. Human Pathology 1993;24:871-9. 78. Heinzer H, Dieckmann KP, Huland E. Virus-related serology and in situ hybridization for the detection of virus DNA among patients with testicular cancer. European Urology 1993;24:271-6. 79. McLachlan RS, Girvin JP, Blume WT, Reichman H. Rasmussen's chronic encephalitis in adults. Archives of Neurology 1993;50:269-74. 80. Niedobitek G, Pitteroff S, Herbst H, Shepherd P, Finn T, Anagnostopoulos et al. Detection of human papillomavirus type 16 DNA in carcinomas of the palatine tonsil. Journal of Clinical Pathology 1990;43:918-21. 81. McCombe PA, Pollard JD, McLeod JG. Chronic inflammatory demyelinating polyradiculoneuropathy. A clinical and electrophysiological study of 92 cases. Brain 1987;110:1617-30. 82. Yoon JW, Kim CJ, Pak CY, McArthur RG. Effects of environmental factors on the development of insulin-dependent diabetes mellitus. [Review] [80 refs]. Clinical & Investigative Medicine - Medecine Clinique et Experimentale 1987;10:457-69. 83. Doeglas HM, Rijnten WJ, Schroder FP, Schirm J. Cold urticaria and virus infections: a clinical and serological study in 39 patients. British Journal of Dermatology 1986; 114: 311-8. 84. Koment RW,.Poor PM. Infection by human cytomegalovirus associated with chronic hematospermia. Urology 1983;22:617-21. 85. Burns JC. Persistent cytomegalovirus infection--the etiology of Sjogren's syndrome. Medical Hypotheses 1983;10:451-60. 86. McLean AM, Paul RE, Jr., Philipps E, Bloom SM, Elta GH, Fawaz KA et al. Chronic erosive gastritis--clinical and radiological features. Journal of the Canadian Association of Radiologists 1982;33:158-62. 87. Nowak TV, Goddard M, Batteiger B, Cummings OW. Evolution of acute cytomegalovirus gastritis to chronic gastrointestinal dysmotility in a onimmunocompromised adult. Gastroenterology 1999;116(4):953-8 88. Geder L, Sanford EJ, Rohner TJ, Rapp F. Cytomegalovirus and cancer of the prostate: in vitro transformation of human cells. Cancer Treatment Reports 1977;61:139-46. 89. Glaser R, Geder L, St.Jeor S, Michelson-Fiske S, Haguenau F. Partial characterization of a herpes-type virus (K9V) derived from Kaposi's sarcoma. Journal of the National Cancer Institute 1977;59:55-60. 90. Scott BB, Hambling MH, Losowsky MS. Viral antibodies and chronic liver disease. Biomedicine 1976;25:163-7. 117 HUMAN HERPES VIRUS Occupation Relvance 1. Herbert AM, Bagg J, Walker DM, Davies KJ, Westmoreland, D. Seroepidemiology of herpes virus infections among dental personnel. Journal Of Dentistry 1995;23:339-42. HUMAN HERPES VIRUS AND CHRONIC FATIGUE SYNDROME Human Herpes Virus (6,7,8) and Chronic Fatigue Syndrome – medline search 1. Marshall GS. Report of a workshop on the epidemiology, natural history, and pathogenesis of chronic fatigue syndrome in adolescents. [Review] [142 refs]. Journal of Pediatrics 1999; 134:395-405. 2. Glaser R,.Kiecolt-Glaser JK. Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome. [Review] [81 refs]. American Journal of Medicine 1998;105:35S-42S. 3. Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. [Review] [576 refs]. Clinical Microbiology Reviews 1997;10:521-67. 4. Levine PH. The use of transfer factors in chronic fatigue syndrome: prospects and problems. [Review] [25 refs]. Biotherapy 1996;9:77-9. 5. Krueger GR, Klueppelberg U, Hoffmann A, Ablashi DV. Clinical correlates of infection with human herpesvirus-6. [Review] [156 refs]. In Vivo 1994;8:457-85. 6. Krueger GR,.Ferrer A, V. A unifying concept of viral immunopathogenesis of proliferative and aproliferative diseases (working hypothesis). [Review] [86 refs]. In Vivo 1994;8:493-9. 7. Moutschen M, Triffaux JM, Demonty J, Legros JJ, Lefebvre PJ. Pathogenic tracks in fatigue syndromes. [Review] [95 refs]. Acta Clinica Belgica 1994;49:274-89. 8. Ablashi DV. Viral studies of chronic fatigue syndrome. [Review] [39 refs]. Clinical Infectious Diseases 1994;18 Suppl 1:S130-S133. 9. Mawle AC, Reyes M, Schmid DS. Is chronic fatigue syndrome an infectious disease?. [Review] [71 refs]. Infectious Agents & Disease 1993;2:333-41. 10. Bond PA. A role for herpes simplex virus in the aetiology of chronic fatigue syndrome and related disorders. [Review] [84 refs]. Medical Hypotheses 1993;40:301-8. 11. Straus SE. Studies of herpesvirus infection in chronic fatigue syndrome. [Review] [32 refs]. Ciba Foundation Symposium 1993;173:132-9. 12. Chou S. Human herpesvirus 6 infection and associated disease. [Review] [46 refs]. Journal of Laboratory & Clinical Medicine 1993;121:388-93. 13. Kyle DV,.deShazo RD. Chronic fatigue syndrome: a conundrum. [Review] [36 refs]. American Journal of the Medical Sciences 1992;303:28-34. 118 14. Ablashi DV, Zompetta C, Lease C, Josephs SF, Balachandra N, Komaroff AL et al. Human herpesvirus 6 (HHV6) and chronic fatigue syndrome (CFS). [Review] [27 refs]. Canada Diseases Weekly Report 1991;17 Suppl 1E:33-40. 15. Rand KH. Chronic fatigue syndrome: fact or fiction. Medical Section Proceedings 1991;135-44. 16. Durack DT,.Street AC. Fever of unknown origin--reexamined and redefined. [Review] [52 refs]. Current Clinical Topics in Infectious Diseases 1991;11:35-51. 17. Miller G. Molecular approaches to epidemiologic evaluation of viruses as risk factors for patients who have chronic fatigue syndrome. Reviews of Infectious Diseases 1991;13 Suppl 1:S119-S122. 18. Denman AM. The chronic fatigue syndrome: a return to common sense. [Review] [23 refs]. Postgraduate Medical Journal 1990;66:499-501. 19. De Vinci C, Levine PH, Pizza G, Fudenberg HH, Orens P, Pearson G et al. Lessons from a pilot study of transfer factor in chronic fatigue syndrome. Biotherapy 1996;9:87-90. 20. Vojdani A,.Lapp CW. Interferon-induced proteins are elevated in blood samples of patients with chemically or virally induced chronic fatigue syndrome. Immunopharmacology & Immunotoxicology 1999;21:175-202. 21. See DM, Cimoch P, Chou S, Chang J, Tilles J. The in vitro immunomodulatory effects of glyconutrients on peripheral blood mononuclear cells of patients with chronic fatigue syndrome. Integrative Physiological & Behavioral Science 1998;33:280-7. 22. Ablashi DV, Eastman HB, Owen CB, Roman MM, Friedman J, Zabriskie JB et al. Frequent HHV-6 reactivation in multiple sclerosis (MS) and chronic fatigue syndrome (CFS) patients. Journal of Clinical Virology 2000;16:179-91. 23. Komaroff AL,.Buchwald DS. Chronic fatigue syndrome: an update. [Review] [97 refs]. Annual Review of Medicine 1998;49:1-13. 24. Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50:25-30. 25. Sairenji T, Yamanishi K, Tachibana Y, Bertoni G, Kurata T. Antibody responses to Epstein-Barr virus, human herpesvirus 6 and human herpesvirus 7 in patients with chronic fatigue syndrome. Intervirology 1995;38:269-73. 26. Patnaik M, Komaroff AL, Conley E, Ojo-Amaize EA, Peter JB. Prevalence of IgM antibodies to human herpesvirus 6 early antigen (p41/38) in patients with chronic fatigue syndrome [published erratum appears in J Infect Dis 1995 Dec;172(6):1643]. Journal of Infectious Diseases 1995;172:1364-7. 27. Di Luca D, Zorzenon M, Mirandola P, Colle R, Botta GA, Cassai E. Human herpesvirus 6 and human herpesvirus 7 in chronic fatigue syndrome. Journal of Clinical Microbiology 1995;33:1660-1. 119 28. Manian FA. Simultaneous measurement of antibodies to Epstein-Barr virus, human herpesvirus 6, herpes simplex virus types 1 and 2, and 14 enteroviruses in chronic fatigue syndrome: is there evidence of activation of a nonspecific polyclonal immune response? [see comments]. Clinical Infectious Diseases 1994;19:448-53. 29. Yalcin S, Kuratsune H, Yamaguchi K, Kitani T, Yamanishi K. Prevalence of human herpesvirus 6 variants A and B in patients with chronic fatigue syndrome. Microbiology & Immunology 1994;38:587-90. 30. Ewig S. [Chronic fatigue and herpes virus antibodies]. [German]. Deutsche Medizinische Wochenschrift 1994;119:1296. 31. Levine PH, Jacobson S, Pocinki AG, Cheney P, Peterson D, Connelly RR et al. Clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome [see comments]. Archives of Internal Medicine 1992;152:1611-6. 32. Buchwald D, Cheney PR, Peterson DL, Henry B, Wormsley SB, Geiger A et al. A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection [see comments]. Annals of Internal Medicine 1992;116:103-13. 33. Marshall GS, Gesser RM, Yamanishi K, Starr SE. Chronic fatigue in children: clinical features, Epstein-Barr virus and human herpesvirus 6 serology and long term follow up. Pediatric Infectious Disease Journal 1991;10:287-90. 34. Gupta S,.Vayuvegula B. A comprehensive immunological analysis in chronic fatigue syndrome. Scandinavian Journal of Immunology 1991;33:319-27. 35. Read R, Larson E, Harvey J, Edwards A, ThoMSon B, Briggs M et al. Clinical and laboratory findings in the Paul-Bunnell negative glandular fever-fatigue syndrome. Journal of Infection 1990;21:157-65. 36. Wallace HL, Natelson B, Gause W, Hay J. Human herpesviruses in chronic fatigue syndrome. Clinical & Diagnostic Laboratory Immunology 1999;6:216-23. 37. Ablashi DV, Levine PH, De Vinci C, Whitman JE, Jr., Pizza G, Viza D. Use of anti HHV-6 transfer factor for the treatment of two patients with chronic fatigue syndrome (CFS). Two case reports. Biotherapy 1996;9:81-6. 38. Albrecht F. Chronic fatigue syndrome [letter]. Journal of the American Academy of Child & Adolescent Psychiatry 2000;39:808-9. 39. Enbom M, Linde A, Evengard B. No evidence of active infection with human herpesvirus 6 (HHV-6) or HHV-8 in chronic fatigue syndrome [letter]. Journal of Clinical Microbiology 2000;38:2457. 40. Stein MT, First LR, Friedman SB. Twelve-year-old girl with chronic fatigue, school absence, and fluctuating somatic symptoms. Journal of Developmental & Behavioral Pediatrics 1998; 19:196-201. 41. Levine PH, Dale JK, Benson-Grigg E, Fritz S, Grufferman S, Straus SE. A cluster of cases of chronic fatigue and chronic fatigue syndrome: clinical and immunologic studies. Clinical Infectious Diseases 1996;23:408-9 120 42. Straus SE. Chronic fatigue syndrome [editorial]. BMJ 1996;313:831-2. 43. Ghahramani M,.Gooriah V. Chronic fatigue syndrome associated with a psychotic state resulting in multiple murders. Bulletin of the American Academy of Psychiatry & the Law 1995;23:613-6. 44. Swanink CM, Vercoulen JH, Bazelmans E, Fennis JF, Bleijenberg G, van d et al. Viral antibodies in chronic fatigue syndrome [letter; comment]. Clinical Infectious Diseases 1995;21:708-9. 45. Ife S. Influence of patients' expectations on disease [letter]. BMJ 1994;309:1160-1. 46. Levine PH,.Komaroff AL. Human herpesvirus type 6 and chronic fatigue syndrome [letter; comment]. Archives of Internal Medicine 1993;153:661. 47. Berneman ZN, Gallo RC, Ablashi DV, Frenkel N, Katsafanas G, Kramarsky B et al. Human herpesvirus 7 (HHV-7) strain JI: independent confirmation of HHV-7 [letter]. Journal of Infectious Diseases 1992;166:690-1. 48. Reeves WC, Pellett PE, Gary H, Jr. The chronic fatigue syndrome controversy [letter; comment]. Annals of Internal Medicine 1992;117:343. 49. McLaughlin B. Virology laboratory diagnosis of chronic fatigue syndrome. Canada Diseases Weekly Report 1991;17 Suppl 1E:51-5. 50. McGuire TA. Recurrent upper respiratory infection, persistent paravertebral thoracolumbar muscle spasm, and fatigue associated with chronic active Epstein-Barr virus infection. Maryland Medical Journal 1991;40:595-6. 51. Stern K. Chronic fatigue syndrome. New disease on the horizon. Journal of Dental Hygiene 1991;65:39-41. 52. Evans AS. Chronic fatigue syndrome: thoughts on pathogenesis. Reviews of Infectious Diseases 1991;13 Suppl 1:S56-S59. 53. Josephs SF, Henry B, Balachandran N, Strayer D, Peterson D, Komaroff AL et al. HHV-6 reactivation in chronic fatigue syndrome [letter]. Lancet 1991;337:1346-7. 54. Chronic fatigue syndrome [letter; comment]. JAMA 1991;265:357-8. 55. Buchwald D, Freedman AS, Ablashi DV, Sullivan JL, Caligiuri M, Weinberg et al. A chronic "postinfectious" fatigue syndrome associated with benign lymphoproliferation, B-cell proliferation, and active replication of human herpesvirus-6. Journal of Clinical Immunology 1990;10:335-44. 56. Lopez-Navidad A,.Domingo P. Chronic infectious mononucleosis [letter; comment]. Journal of Internal Medicine 1990;228:541-3. 57. Talstad I, Scott H, Jenum P, Linde A. Chronic infectious mononucleosis; a case report [see comments]. Journal of Internal Medicine 1989;226:459-62. 58. Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50:25-30. 121 59. Manian FA. Simultaneous measurement of antibodies to Epstein-Barr virus, human herpesvirus 6, herpes simplex virus types 1 and 2, and 14 enteroviruses in chronic fatigue syndrome: is there evidence of activation of a nonspecific polyclonal immune response? [see comments]. Clinical Infectious Diseases 1994;19:448-53. 60. Levine PH, Jacobson S, Pocinki AG, Cheney P, Peterson D, Connelly RR et al. Clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome [see comments]. Archives of Internal Medicine 1992;152 :1611-6. 61 . Gow JW, Behan WM, Clements GB, Woodall C, Riding M, Behan PO. Enteroviral RNA sequences detected by polymerase chain reaction in muscle of patients with postviral fatigue syndrome [see comments]. BMJ 1991;302:692-6 Human Herpes Virus (6,7,8) and Chronic Fatigue Syndrome – science citation index search 1. Black JB,.Pellett PE. Human herpesvirus 7. Reviews In Medical Virology 1999; 9: 245-62. 2. Deleon FL, Fernandez JG, Mazuelos EM, Garciabragado F. Infection with human herpesvirus type-6 - Epidemiology, Immunopathology and clinical implications. Revista Clinica Espanola 1992; 190:37-42. 3. Evengard B, Schacterle RS, Komaroff AL. Chronic fatigue syndrome: new insights and old ignorance. Journal Of Internal Medicine 1999;246:455-69. 4. Holmes GP. The chronic fatigue syndrome. Current Opinion In Infectious Diseases 1991;4:615-20. 5. Maticic M,.Vidmar L. Chronic fatigue syndrome. Zdravstveni Vestnik 1991;60:383-6. 6. Mawle AC, Nisenbaum R, Dobbins JG, Gary HE, Stewart JA, Reyes M et al. Seroepidemiology of chronic fatigue syndrome: A case-control study. Clinical Infectious Diseases 1995;21:1386-9. 7. Wilborn F, Schmidt CA, Brinkmann V, Jendroska K, Oettle H, Siegert W. A potential role for human herpesvirus type-6 in nervous-system disease. Journal Of Neuroimmunology 1994;49:213-4. HUMAN HERPES VIRUS AND MULTIPLE SCLEROSIS Human Herpes Virus and Multiple Sclerosis – medline search 1. Clark DA. Human herpesvirus 6. [Review] [145 refs]. Reviews in Medical Virology 2000;10:155-73. 2. Berti R, Soldan SS, Akhyani N, McFarland HF, Jacobson S. Extended observations on the association of HHV-6 and multiple sclerosis. [Review] [17 refs]. Journal of Neurovirology 2000;6 Suppl 2:S85-S87. 3. Azoulay-Cayla A. [Is multiple sclerosis a disease of viral origin?]. [Review] [51 refs] [French]. Pathologie Biologie 2000;48:4-14. 122 4. Kosuge H. HHV-6, 7 and their related diseases. [Review] [104 refs]. Journal of Dermatological Science 2000;22:205-12. 5. Bergstrom T. Herpesviruses--a rationale for antiviral treatment in multiple sclerosis. [Review] [160 refs]. Antiviral Research 1999;41:1-19. 6. Campadelli-Fiume G, Mirandola P, Menotti L. Human herpesvirus 6: An emerging pathogen. [Review] [105 refs]. Emerging Infectious Diseases 1999;5:353-66. 7. Dockrell DH, Smith TF, Paya CV. Human herpesvirus 6. [Review] [56 refs]. Mayo Clinic Proceedings 1999;74:163-70. 8. Meinl E. Concepts of viral pathogenesis of multiple sclerosis. [Review] [52 refs]. Current Opinion in Neurology 1999;12:303-7. 9. Jacobson S. Association of human herpesvirus-6 and multiple sclerosis: here we go again? [editorial; comment]. [Review] [18 refs]. Journal of Neurovirology 1998;4 :471-3. 10. Kimberlin DW,.Whitley RJ. Human herpesvirus-6: neurologic implications of a newly-described viral pathogen [see comments]. [Review] [130 refs]. Journal of Neurovirology 1998;4:474-85. 11. Monteyne P, Bureau JF, Brahic M. Viruses and multiple sclerosis. [Review] [38 refs]. Current Opinion in Neurology 1998;11:287-91. 12. Kimberlin DW. Human herpesviruses 6 and 7: identification of newly recognized viral pathogens and their association with human disease. [Review] [151 refs]. Pediatric Infectious Disease Journal 1998;17:59-67. 13. Carrigan DR,.Knox KK. Human herpesvirus six and multiple sclerosis. Multiple Sclerosis 1997;3:390-4. 14. Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. [Review] [576 refs]. Clinical Microbiology Reviews 1997;10:521-67. 15. Lyall EG. Human herpesvirus 6: primary infection and the central nervous system. [Review] [36 refs]. Pediatric Infectious Disease Journal 1996;15:693-6. 16. Merrill JE, Graves MC, Mulder DG. Autoimmune disease and the nervous system. Biochemical, molecular, and clinical update. [Review] [130 refs]. Western Journal of Medicine 1992; 156:639-46. 17. Draganescu N. Some trends of research in the domain of viral neuroinfections approached in the "Stefan S. Nicolau" Institute of Virology. Virologie 1985;36:47-56. 18. Vella V. A review of the etiology of multiple sclerosis. [Review] [122 refs]. Italian Journal of Neurological Sciences 1984;5:347-56. 19. Esiri MM. Immunohistological studies of immunoglobulin-containing cells and viral antigens in some inflammatory diseases of the nervous system. Progress in Brain Research 1983; 59:209-19. 20. Dal Canto MC,.Rabinowitz SG. Experimental models of virus-induced demyelination of the central nervous system. [Review] [100 refs]. Annals of Neurology 1982;11:109-27. 123 21. Horrobin DF,.Lieb J. A biochemical basis for the actions of lithium on behaviour and on immunity: relapsing and remitting disorders of inflammation and immunity such as multiple sclerosis or recurrent herpes as manic-depression of the immune system. Medical Hypotheses 1981;7:891-905. 22. Borecky L. Interactions between viral infection and immune mechanisms. [Review] [69 refs]. Comparative Immunology, Microbiology & Infectious Diseases 1980;3:381-90. 23. Moller E, Strom H, Al Balaghi S. Role of polyclonal activation in specific immune responses. Relevance for findings of antibody activity in various diseases. Scandinavian Journal of Immunology 1980;12:177-82. 24. Lycke J, Svennerholm B, Hjelmquist E, Frisen L, Badr G, Andersson M et al. Acyclovir treatment of relapsing-remitting multiple sclerosis. A randomized, placebo controlled, double-blind study. Journal of Neurology 1996;243:214-24. 25. Rosengren LE, Lycke J, Andersen O. Glial fibrillary acidic protein in CSF of multiple sclerosis patients: relation to neurological deficit. Journal of the Neurological Sciences 1995;133:61-5. 26. Rotola A, Caselli E, Cassai E, Tola MR, Granieri E, Luca DD. Novel human herpesviruses and multiple sclerosis. Journal of Neurovirology 2000;6 Suppl 2:S88-S91. 27. Santoro F, Kennedy PE, Locatelli G, Malnati MS, Berger EA, Lusso P. CD46 is a cellular receptor for human herpesvirus 6. Cell 1999;99:817-27. 28. Esposito M, Venkatesh V, Otvos L, Weng Z, Vajda S, Banki K et al. Human transaldolase and cross-reactive viral epitopes identified by autoantibodies of multiple sclerosis patients. Journal of Immunology 1999;163:4027-32. 29. Tsunoda I, Tolley ND, Theil DJ, Whitton JL, Kobayashi H, Fujinami RS. Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA. Brain Pathology 1999;9:481-93. 30. Morris C, Luppi M, McDonald M, Barozzi P, Torelli G. Fine mapping of an apparently targeted latent human herpesvirus type 6 integration site in chromosome band 17p13.3. Journal of Medical Virology 1999;58:69-75. 31. Albright AV, Lavi E, Black JB, Goldberg S, O'Connor MJ, Gonzalez S et al. The effect of human herpesvirus-6 (HHV-6) on cultured human neural cells: oligodendrocytes and microglia [see comments]. Journal of Neurovirology 1998;4:486-94. 32. Ufret-Vincenty RL, Quigley L, Tresser N, Pak SH, Gado A, Hausmann S et al. In vivo survival of viral antigen-specific T cells that induce experimental autoimmune ncephalomyelitis. Journal of Experimental Medicine 1998;188:1725-38. 33. Kaufman MD. Do microbes with peptides mimicking myelin cause multiple sclerosis if the T cell response to their unique peptides is limited? Journal of Theoretical Biology 1998;193:691-708. 34. Chou YK, Weinberg AD, Buenafe A, Bourdette DN, Whitham R, Kaleeba JA et al. MHC-restriction, cytokine profile, and immunoregulatory effects of human T cells specific for TCR V beta CDR2 peptides: comparison with myelin basic protein-specific T cells. Journal of Neuroscience Research 1996;45:838-51. 124 35. Stinissen P, Vandevyver C, Raus J, Zhang J. Superantigen reactivity of gamma delta T cell clones isolated from patients with multiple sclerosis and controls. Cellular Immunology 1995;166:227-35. 36. Li F, Linan MJ, Stein MC, Faustman DL. Reduced expression of peptide-loaded HLA class I molecules on multiple sclerosis lymphocytes [see comments]. Annals of Neurology 1995;38:147-54. 37. Collins AR. Virus-ligand interactions of OC43 coronavirus with cell membranes. Advances in Experimental Medicine & Biology 1993;342:285-91. 38 Weber F, Meinl E, Drexler K, Czlonkowska A, Huber S, Fickenscher H et al. Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells. Proceedings of the National Academy of Sciences of the United States of America 1993;90:11049-53. 39. Hartung HP, Michels M, Reiners K, Seeldrayers P, Archelos JJ, Toyka KV. Soluble ICAM-1 serum levels in multiple sclerosis and viral encephalitis. Neurology 1993;43:2331-5. 40. Chou YK, Bourdette DN, Offner H, Whitham R, Wang RY, Hashim GA et al. Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis. Journal of Neuroimmunology 1992;38:105-13. 41. Wirguin I, Brenner T, Steinitz M, AbraMSky O. In vitro synthesis of antibodies to myelin antigens by Epstein-Barr virus-transformed B lymphocytes from patients with neurologic disorders. Journal of the Neurological Sciences 1991;104:92-6. 42. Uhlig H,.Dernick R. Monoclonal autoantibodies derived from multiple sclerosis patients and control persons and their reactivities with antigens of the central nervous system. Autoimmunity 1989;5:87-99. 43. Kolstad A, Hannestad K, Vandvik B, Vartdal F. Multiple sclerosis patients have a high frequency of an HLA-DQ beta epitope defined by a human-human hybridoma antibody. Tissue Antigens 1989;33:546-9. 44. Shaw SY, Laursen RA, Lees MB. Analogous amino acid sequences in myelin proteolipid and viral proteins. FEBS Letters 1986;207:266-70. 45. Tsukamoto T, Seki H, Takase S, Sekizawa T, Nakamura S. Significant increase in immunosuppressive acidic protein (IAP) in serum of patients with multiple sclerosis and other inflammatory neurological disorders. Journal of the Neurological Sciences 1986;75:353-61. 46. Prasad R. Immunoglobulin levels in serum and cerebrospinal fluid in certain viral infections of the central nervous system. Journal of Infectious Diseases 1983;148:607. 47. Walker JE, Cook JD, Harrison P, Stastny P. HLA and the response of lymphocytes to viral antigens in patients with multiple sclerosis. Human Immunology 1982;4:71-8. 48. Pelc S, De Maertelaere E, Denolin-Reubens R. CSF cytology of acute viral meningitis and meningoencephalitis. European Neurology 1981;20:95-102. 49. Ferrante P, Mancuso R, Pagani E, Guerini FR, Calvo MG, Saresella M et al. Molecular evidences for a role of HSV-1 in multiple sclerosis clinical acute attack. Journal of Neurovirology 2000;6 Suppl 2:S109-S114. 125 50. Taus C, Pucci E, Cartechini E, Fie A, Giuliani G, Clementi M et al. Absence of HHV-6 and HHV-7 in cerebrospinal fluid in relapsing-remitting multiple sclerosis. Acta Neurologica Scandinavica 2000;101:224-8. 51. Ablashi DV, Eastman HB, Owen CB, Roman MM, Friedman J, Zabriskie JB et al. Frequent HHV-6 reactivation in multiple sclerosis (MS) and chronic fatigue syndrome (CFS) patients. Journal of Clinical Virology 2000;16:179-91. 52. Soldan SS, Leist TP, Juhng KN, McFarland HF, Jacobson S. Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients. Annals of Neurology 2000;47:306-13. 53. Mirandola P, Stefan A, Brambilla E, Campadelli-Fiume G, Grimaldi LM. Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients. Neurology 1999;53:1367-8. 54. Rotola A, Cassai E, Tola MR, Granieri E, Di Luca D. Human herpesvirus 6 is latent in peripheral blood of patients with relapsing-remitting multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 1999;67:529-31. 55. Ongradi J, Rajda C, Marodi CL, Csiszar A, Vecsei L. A pilot study on the antibodies to HHV-6 variants and HHV-7 in CSF of MS patients. Journal of Neurovirology 1999;5:52932. 56. Enbom M, Wang FZ, Fredrikson S, Martin C, Dahl H, Linde A. Similar humoral and cellular immunological reactivities to human herpesvirus 6 in patients with multiple sclerosis and controls. Clinical & Diagnostic Laboratory Immunology 1999;6:545-9. 57. Ablashi DV, Lapps W, Kaplan M, Whitman JE, Richert JR, Pearson GR. Human Herpesvirus-6 (HHV-6) infection in multiple sclerosis: a preliminary report. Multiple Sclerosis 1998;4:490-6. 58 Mayne M, Krishnan J, Metz L, Nath A, Auty A, Sahai BM et al. Infrequent detection of human herpesvirus 6 DNA in peripheral blood mononuclear cells from multiple sclerosis patients. Annals of Neurology 1998;44:391-4. 59. Myhr KM, Riise T, Barrett-Connor E, Myrmel H, Vedeler C, Gronning M et al. Altered antibody pattern to Epstein-Barr virus but not to other herpesviruses in multiple sclerosis: a population based case-control study from western Norway. Journal of Neurology, Neurosurgery & Psychiatry 1998;64:539-42. 60. Soldan SS, Berti R, Salem N, Secchiero P, Flamand L, Calabresi PA et al. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA [see comments]. Nature Medicine 1997;3:1394-7. 61. Nielsen L, Larsen AM, Munk M, Vestergaard BF. Human herpesvirus-6 immunoglobulin G antibodies in patients with multiple sclerosis. Acta Neurologica Scandinavica 1997;Supplementum. 169:76-8. 62. Kim JS, Lee KS, Park JH, Kim MY, Shin WS. Detection of human herpesvirus 6 variant A in peripheral blood mononuclear cells from multiple sclerosis patients. European Neurology 2000;43:170-3. 126 63. Hay KA,.Tenser RB. Leukotropic herpesviruses in multiple sclerosis. Multiple Sclerosis 2000;6:66-8. 64. Blumberg BM, Mock DJ, Powers JM, Ito M, Assouline JG, Baker JV et al. The HHV6 paradox: ubiquitous commensal or insidious pathogen? A two-step in situ PCR approach. Journal of Clinical Virology 2000;16:159-78. 65. Friedman JE, Lyons MJ, Cu G, Ablashl DV, Whitman JE, Edgar M et al. The association of the human herpesvirus-6 and MS. Multiple Sclerosis 1999;5:355-62. 66. Goldberg SH, Albright AV, Lisak RP, Gonzalez-Scarano F. Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis. Journal of Neurovirology 1999;5:134-9. 67. Merelli E, Bedin R, Sola P, Barozzi P, Mancardi GL, Ficarra G et al. Human herpes virus 6 and human herpes virus 8 DNA sequences in brains of multiple sclerosis patients, normal adults and children. Journal of Neurology 1997;244:450-4. 68. Martin C, Enbom M, Soderstrom M, Fredrikson S, Dahl H, Lycke J et al. Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis. Acta Neurologica Scandinavica 1997;95:280-3. 69. Dybwad A, Flrre O, Sioud M. Probing for cerebrospinal fluid antibody specificities by a panel of random peptide libraries. Autoimmunity 1997;25:85-9. 70. Ferrante P, Omodeo-Zorini E, Zuffolato MR, Mancuso R, Caldarelli S, R et al. Human T-cell lymphotropic virus tax and Epstein-Barr virus DNA in peripheral blood of multiple sclerosis patients during acute attack. Acta Neurologica Scandinavica 1997;Supplementum. 169:79-85. 71. Sanders VJ, Felisan S, Waddell A, Tourtellotte WW. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. Journal of Neurovirology 1996;2:249-58. 72. Carrigan DR, Harrington D, Knox KK. Subacute leukoencephalitis caused by CNS infection with human herpesvirus-6 manifesting as acute multiple sclerosis. Neurology 1996;47:145-8. 73. Liedtke W, Malessa R, Faustmann PM, Eis-Hubinger AM. Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. Journal of Neurovirology 1995;1:253-8. 74. Torelli G, Barozzi P, Marasca R, Cocconcelli P, Merelli E, Ceccherini-Nelli L et al. Targeted integration of human herpesvirus 6 in the p arm of chromosome 17 of human peripheral blood mononuclear cells in vivo. Journal of Medical Virology 1995;46:178-88. 75. Challoner PB, Smith KT, Parker JD, MacLeod DL, Coulter SN, Rose TM et al. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America 1995;92:7440-4. 76. Wilborn F, Schmidt CA, Brinkmann V, Jendroska K, Oettle H, Siegert W. A potential role for human herpesvirus type 6 in nervous system disease. Journal of Neuroimmunology 1994;49:213-4. 127 77. Sola P, Merelli E, Marasca R, Poggi M, Luppi M, Montorsi M et al. Human herpesvirus 6 and multiple sclerosis: survey of anti-HHV-6 antibodies by immunofluorescence analysis and of viral sequences by polymerase chain reaction. Journal of Neurology, Neurosurgery & Psychiatry 1993;56:917-9. 78. Hunter SF,.Hafler DA. Ubiquitous pathogens: links between infection and autoimmunity in MS? [editorial; comment]. Neurology 2000;55:164-5. 79. Luppi M, Barozzi P, Morris CM, Merelli E, Torelli G. Integration of human herpesvirus 6 genome in human chromosomes [letter; comment]. Lancet 1998;352:1707-8. 80. Fillet AM, Lozeron P, Agut H, Lyon-Caen O, Liblau R. HHV-6 and multiple sclerosis [letter; comment]. Nature Medicine 1998;4:537. 81. Coates AR,.Bell J. HHV-6 and multiple sclerosis [letter; comment]. Nature Medicine 1998;4:537-8. 82. Steinman L,.Oldstone MB. More mayhem from molecular mimics [news; comment]. Nature Medicine 1997; 3:1321-2. 83. Berardelli P. Herpesvirus linked to multiple sclerosis [news]. Science 1997;278:1710. 84. Novoa LJ, Nagra RM, Nakawatase T, Edwards-Lee T, Tourtellotte WW, Cornford ME. Fulminant demyelinating encephalomyelitis associated with productive HHV-6 infection in an immunocompetent adult. Journal of Medical Virology 1997;52:301-8. 85. Merelli E, Sola P, Barozzi P, Torelli G. An encephalitic episode in a multiple sclerosis patient with human herpesvirus 6 latent infection. Journal of the Neurological Sciences 1996;137:42-6. 86. Herndon RM. Herpesviruses in multiple sclerosis [editorial; comment]. Neurology 1996; 53:123-4 Archives of 87. Weiss RA,.Schulz TF. Viruses and multiple sclerosis [editorial]. Multiple Sclerosis 1995;1:59-60. 88. Luppi M, Marasca R, Barozzi P, Ferrari S, Ceccherini-Nelli L, Batoni G et al. Three cases of human herpesvirus-6 latent infection: integration of viral genome in peripheral blood mononuclear cell DNA. Journal of Medical Virology 1993;40:44-52. 89. Steinberg J, Rukstalis DB, Vickers MA, Jr. Acute urinary retention secondary to Herpes simplex meningitis. Journal of Urology 1991;145:359-60. 90. Multiple sclerosis. Veterinary Record 1982;110:94-5. 91. Woyciechowska JL, Dambrosia J, Tzan N, Madden DL. Multiple sclerosis, antiviral antibodies [letter]. Lancet 1982;2:1461-2. 92. Ferrante P, Caputo D, Barbesti S, Fasan M. Viral antibodies in multiple sclerosis. Italian Journal of Neurological Sciences 1982;3:115-8. 93 Alter M. Multiple sclerosis, herpes viruses, and immunity. Lancet 1981;2:1224-5. 128 Human Herpes Virus and Multiple Sclerosis – science citation index search 1 Berti R,.Jacobson S. Role of viral infection in the aetiology of multiple sclerosis Status of current knowledge and therapeutic implications. Cns Drugs 1999;12:1-7. 2 Cermelli C,.Jacobson S. Viruses and multiple sclerosis. Viral Immunology 2000;13:255-67. 3 Gordon L, McQuaid S, Cosby SL. Detection of herpes simplex virus (types 1 and 2) and human herpesvirus 6 DNA in human brain tissue by polymerase chain reaction. Clinical And Diagnostic Virology 1996;6:33-40. 4 Macgregor HS,.Latiwonk QI. Complex role of gamma-herpesviruses in multiple sclerosis and infectious-mononucleosis. Neurological Research 1993;15:391-4. 5 Yoshikawa T,.Asano Y. Central nervous system complications in human herpesvirus 6 infection. Brain & Development 2000;22:307-14. Human herpes and coronary heart disease 1. Havlik RJ, Blackwelder WC, Kaslow R, Castelli W. Unlikely association between clinically apparent herpesvirus infection and coronary incidence at older ages. The Framingham Heart Study. Arteriosclerosis 1989;9:877-80. 2. Ye D, Nichols TC, Dehmer GJ, Tate DA, Wehbie RS, Quinlivan EB. Absence of human herpesvirus 8 genomes in coronary atherosclerosis in immunocompetent patients. American Journal of Cardiology 1997;79:1245-7 EPSTEIN BARR VIRUS Occupational relevance 1. Herbert AM, Bagg J, Walker DM, Davies KJ, Westmoreland, D. Seroepidemiology of herpes virus infections among dental personnel. Journal Of Dentistry 1995;23:339-42. 2. Stancek D, Kosecka G, Oltman M, Keleova A, Jahnova E. Links between prolonged exposure to xenobiotics, increased incidence of hepatopathies, immunological disturbances and exacerbation of latent Epstein-Barr virus infections. International Journal of Immunopharmacology 1995;17:321-8. EPSTEIN BARR VIRUS AND CHRONIC FATIGUE SYNDROME Epstein Barr Virus and Chronic Fatigue Syndrome – medline search 1. Lopez-Navidad A, Domingo P, Lopez-Talavera JC, Rabella N, Verger G. EpsteinBarr virus infection associated with interstitial nephritis and chronic fatigue. [Review] [20 refs]. Scandinavian Journal of Infectious Diseases 1996;28:185-7. 129 2. Schuster V,.Kreth HW. Epstein-Barr virus infection and associated diseases in children. I. Pathogenesis, epidemiology and clinical aspects. [Review] [128 refs]. European Journal of Pediatrics 1992;151:718-25. 3. Joncas JH. Search for an association between Epstein-Barr virus infection and the chronic fatigue syndrome. Canada Diseases Weekly Report 1991;17 Suppl 1E:43-7. 4. Sumaya CV. Serologic and virologic epidemiology of Epstein-Barr virus: relevance to chronic fatigue syndrome. [Review] [39 refs]. Reviews of Infectious Diseases 1991;13 Suppl 1:S19-S25. 5. Grafman J, Johnson R, Jr., Scheffers M. Cognitive and mood-state changes in patients with chronic fatigue syndrome. [Review] [64 refs]. Reviews of Infectious Diseases 1991;13 Suppl 1:S45-S52. 6. Jones JF. Epstein-Barr virus and the chronic fatigue syndrome: a short review. [Review] [22 refs]. Microbiological Sciences 1988;5:366-9. 7. Schooley RT. Chronic fatigue syndrome: a manifestation of Epstein-Barr virus infection?. [Review] [91 refs]. Current Clinical Topics in Infectious Diseases 1988;9:126-46. 8. Mawle AC, Reyes M, Schmid DS. Is chronic fatigue syndrome an infectious disease?. [Review] [71 refs]. Infectious Agents & Disease 1993;2:333-41. 9. Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. Journal of Medical Virology 1996;50:25-30. 10. Straus SE. Studies of herpesvirus infection in chronic fatigue syndrome. [Review] [32 refs]. Ciba Foundation Symposium 1993;173:132-9. 11. Hana I, Vrubel J, Pekarek J, Cech K. The influence of age on transfer factor treatment of cellular immunodeficiency, chronic fatigue syndrome and/or chronic viral infections. Biotherapy 1996;9:91-5. 12. Fark AR. Infectious mononucleosis, Epstein-Barr virus, and chronic fatigue syndrome: a prospective case series [see comments]. Journal of Family Practice 209; 32: 202-6. 13. Tedeschi R, Foong YT, Cheng HM, dePaoli P, Lehtinen T, Elfborg T et al. The disease associations of the antibody response against the Epstein-Barr virus transactivator protein ZEBRA can be separated into different epitopes. Journal of General Virology 1995;76:1393-400. 14. Schmaling KB,.Jones JF. MMPI profiles of patients with chronic fatigue syndrome. Journal of Psychosomatic Research 1996;40:67-74. 15. Sairenji T, Yamanishi K, Tachibana Y, Bertoni G, Kurata T. Antibody responses to Epstein-Barr virus, human herpesvirus 6 and human herpesvirus 7 in patients with chronic fatigue syndrome. Intervirology 1995;38:269-73. 130 16. Swanink CM, van der Meer JW, Vercoulen JH, Bleijenberg G, Fennis JF, Galama JM. Epstein-Barr virus (EBV) and the chronic fatigue syndrome: normal virus load in blood and normal immunologic reactivity in the EBV regression assay. Clinical Infectious Diseases 1995;20:1390-2. 17. Manian FA. Simultaneous measurement of antibodies to Epstein-Barr virus, human herpesvirus 6, herpes simplex virus types 1 and 2, and 14 enteroviruses in chronic fatigue syndrome: is there evidence of activation of a nonspecific polyclonal immune response? [see comments]. Clinical Infectious Diseases 1994;19:448-53. 18. Natelson BH, Ye N, Moul DE, Jenkins FJ, Oren DA, Tapp WN et al. High titers of anti-Epstein-Barr virus DNA polymerase are found in patients with severe fatiguing illness. Journal of Medical Virology 1994;42:42-6. 19. Whelton CL, Salit I, Moldofsky H. Sleep, Epstein-Barr virus infection, musculoskeletal pain, and depressive symptoms in chronic fatigue syndrome. Journal of Rheumatology 1992;19:939-43. 20. Levine PH, Jacobson S, Pocinki AG, Cheney P, Peterson D, Connelly RR et al. Clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome [see comments]. Archives of Internal Medicine 1992;152 :1611-6. 21. Kawai K,.Kawai A. Studies on the relationship between chronic fatigue syndrome and Epstein-Barr virus in Japan. Internal Medicine 1992;31:313-8. 22. Linde A, Andersson B, Svenson SB, Ahrne H, Carlsson M, Forsberg P et al. Serum levels of lymphokines and soluble cellular receptors in primary Epstein-Barr virus infection and in patients with chronic fatigue syndrome. Journal of Infectious Diseases 1992;165:9941000. 23. Woodward CG,.Cox RA. Epstein-Barr virus serology in the chronic fatigue syndrome. Journal of Infection 1992;24:133-9. 24. Jones JF, Streib J, Baker S, Herberger M. Chronic fatigue syndrome: I. Epstein-Barr virus immune response and molecular epidemiology. Journal of Medical Virology 1991;33 151-8. 25. Matthews DA, Lane TJ, Manu P. Antibodies to Epstein-Barr virus in patients with chronic fatigue. [Review] [71 refs]. Southern Medical Journal 1991;84:832-40. 26. Marshall GS, Gesser RM, Yamanishi K, Starr SE. Chronic fatigue in children: clinical features, Epstein-Barr virus and human herpesvirus 6 serology and long term follow up. Pediatric Infectious Disease Journal 1991;10:287-90. 27. Jones JF. Serologic and immunologic responses in chronic fatigue syndrome with emphasis on the Epstein-Barr virus. [Review] [26 refs]. Reviews of Infectious Diseases 1991;13 Suppl 1:S26-S31. 28. Daugherty SA, Henry BE, Peterson DL, Swarts RL, Bastien S, Thomas RS. Chronic fatigue syndrome in northern Nevada. Reviews of Infectious Diseases 1991;13 Suppl 1:S39S44. 131 29. Okano M, Thiele GM, Purtilo DT. Severe chronic active Epstein-Barr virus infection syndrome and adenovirus type-2 infection. American Journal of Pediatric HematologyOncology 1990;12:168-73. 30. Gold D, Bowden R, Sixbey J, Riggs R, Katon WJ, Ashley R et al. Chronic fatigue. A prospective clinical and virologic study [see comments]. JAMA 1990;264:48-53. 31. Wallace HL, Natelson B, Gause W, Hay J. Human herpesviruses in chronic fatigue syndrome. Clinical & Diagnostic Laboratory Immunology 1999;6:216-23. 32. Wray BB, Gaughf C, Chandler FW, Jr., Berry SS, Latham JE, Wood L et al. Detection of Epstein-Barr virus and cytomegalovirus in patients with chronic fatigue. Annals of Allergy 1993;71:223-6. 33. White PD, Thomas JM, Amess J, Crawford DH, Grover SA, Kangro HO et al. Incidence, risk and prognosis of acute and chronic fatigue syndromes and psychiatric disorders after glandular fever. British Journal of Psychiatry 1998;173:475-81. 34. White PD, Grover SA, Kangro HO, Thomas JM, Amess J, Clare AW. The validity and reliability of the fatigue syndrome that follows glandular fever. Psychological Medicine 1995;25:917-24. 35. White PD, Thomas JM, Amess J, Grover SA, Kangro HO, Clare AW. The existence of a fatigue syndrome after glandular fever. Psychological Medicine 1995;25:907-16. 36. Carver LA, Connallon PF, Flanigan SJ, Crossley-Miller MK. Epstein-Barr virus infection in Desert Storm reservists. Military Medicine 1994;159:580-2. 37. Pallavicini EB, Brambilla G, Porta C, Cannatelli G, Battistini E, Gorini et al. Chronic Epstein-Barr virus infection. Haematologica 1992;77:359-60. 38. Drago F, Romagnoli M, Loi A, Rebora A. Epstein-Barr virus-related persistent erythema multiforme in chronic fatigue syndrome. Archives of Dermatology 1992;128:21722. 39 Smucker DR. Epstein-Barr virus [letter; comment]. Journal of Family Practice 1991;32:456. 40 Powell MA. Epstein-Barr antibody titer and chronic fatigue syndrome. Journal of the American Academy of Nurse Practitioners 1990;2:33-4 EPSTEIN BARR VIRUS AND MULTIPLE SCLEROSIS Epstein Barr Virus and Multiple Sclerosis - medline search 1. Haahr S,.Munch M. The association between multiple sclerosis and infection with Epstein-Barr virus and retrovirus. [Review] [41 refs]. Journal of Neurovirology 2000;6 Suppl 2:S76-S79. 2. Munch M, Hvas J, Christensen T, Moller-Larsen A, Haahr S. The implications of Epstein-Barr virus in multiple sclerosis--a review. [Review] [56 refs]. Acta Neurologica Scandinavica 1997;Supplementum. 169:59-64. 132 3. McHatters GR,.Scham RG. Bird viruses in multiple sclerosis: combination of viruses or Marek's alone?. [Review] [7 refs]. Neuroscience Letters 1995;188:75-6. 4. MacGregor HS,.Latiwonk QI. Complex role of gamma-herpesviruses in multiple sclerosis and infectious mononucleosis. Neurological Research 1993;15:391-4. 5. Haahr S, Sommerlund M, Moller-Larsen A, Mogensen S, Andersen HM. Is multiple sclerosis caused by a dual infection with retrovirus and Epstein-Barr virus? Neuroepidemiology 1992; 11:299-303. 6. Dernick R,.Uhlig H. From host components of virus particles to anti-myelin human monoclonal antibodies obtained by Epstein-Barr virus transformation of lymphocytes from multiple sclerosis patients. [Review] [35 refs]. Behring Institute Mitteilungen 1991;138-45. 7. Warner HB,.Carp RI. Multiple sclerosis etiology--an Epstein-Barr virus hypothesis. Medical Hypotheses 1988;25:93-7. 8. Haahr S, Koch-Henriksen N, Moller-Larsen A, Eriksen LS, Andersen HM. Increased risk of multiple sclerosis after late Epstein-Barr virus infection: a historical prospective study. Multiple Sclerosis 1995;1:73-7. 9. Lindberg C, Andersen O, Vahlne A, Dalton M, Runmarker B. Epidemiological investigation of the association between infectious mononucleosis and multiple sclerosis. Neuroepidemiology 1991;10:62-5. 10. Scotet E, Peyrat MA, Saulquin X, Retiere C, Couedel C, Davodeau F et al. Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes. European Journal of Immunology 1999;29:973-85. 11. van Sechel AC, Bajramovic JJ, van Stipdonk MJ, Persoon-Deen C, Geutskens, SB et al. EBV-induced expression and HLA-DR-restricted presentation by human B cells of alpha B-crystallin, a candidate autoantigen in multiple sclerosis. Journal of Immunology 1999;162:129-35. 12. Lotz M, Tsoukas CD, Hench PK, Carson DA, Vaughan JH. Release of lymphokines following Epstein-Barr virus infection in vitro of blood lymphocytes from patients with autoimmune diseases. Transactions of the Association of American Physicians 1986;99:11424. 13. Felgenhauer K, Schadlich HJ, Nekic M, Ackermann R. Cerebrospinal fluid virus antibodies. A diagnostic indicator for multiple sclerosis? Journal of the Neurological Sciences 1985;71:291-9. 14. Munch M, Riisom K, Christensen T, Moller-Larsen A, Haahr S. The significance of Epstein-Barr virus seropositivity in multiple sclerosis patients? Acta Neurologica Scandinavica 1998;97:171-4. 15. Myhr KM, Riise T, Barrett-Connor E, Myrmel H, Vedeler C, Gronning M et al. Altered antibody pattern to Epstein-Barr virus but not to other herpesviruses in multiple sclerosis: a population based case-control study from western Norway. Journal of Neurology, Neurosurgery & Psychiatry 1998;64:539-42. 133 16. Vaughan JH, Riise T, Rhodes GH, Nguyen MD, Barrett-Connor E, Nyland H. An Epstein Barr virus-related cross reactive autoimmune response in multiple sclerosis in Norway. Journal of Neuroimmunology 1996;69:95-102. 17. Martyn CN, Cruddas M, Compston DA. Symptomatic Epstein-Barr virus infection and multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 1993;56:167-8. 18. Bray PF, Luka J, Bray PF, Culp KW, Schlight JP. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 1992;42:1798-804. 19. Kinnunen E, Valle M, Piirainen L, Kleemola M, Kantanen ML, Juntunen J et al. Viral antibodies in multiple sclerosis. A nationwide co-twin study. Archives of Neurology 1990;47:743-6. 20. Craig JC, Haire M, Merrett JD. T-cell-mediated suppression of Epstein-Barr virus induced B lymphocyte activation in multiple sclerosis. Clinical Immunology & Immunopathology 1988;48:253-60. 21. Shirodaria PV, Haire M, Fleming E, Merrett JD, Hawkins SA, Roberts SD. Viral antibody titers. Comparison in patients with multiple sclerosis and rheumatoid arthritis. Archives of Neurology 1987;44:1237-41. 22. Ferrante P, Castellani P, Barbi M, Bergamini F. The Italian Cooperative Multiple Sclerosis case-control study: preliminary results on viral antibodies. Italian Journal of Neurological Sciences 1987;Suppl 6:45-50. 23. Sumaya CV, Myers LW, Ellison GW, Ench Y. Increased prevalence and titer of Epstein-Barr virus antibodies in patients with multiple sclerosis. Annals of Neurology 1985;17:371-7. 24. Larsen PD, Bloomer LC, Bray PF. Epstein-Barr nuclear antigen and viral capsid antigen antibody titers in multiple sclerosis. Neurology 1985;35:435-8. 25. Fleischer B, Marquardt P, Poser S, Kreth HW. Phenotypic markers and functional characteristics of T lymphocyte clones from cerebrospinal fluid in multiple sclerosis. Journal of Neuroimmunology 1984;7:151-62. 26. Isager H, Cohn J, Hesse J, Vestergaard BF. Antibodies to herpes simplex and Epstein-Barr viruses in Faroese children: association with sibship size, height and age. Acta Pathologica, Microbiologica, et Immunologica Scandinavica - Section B, Microbiology 1983;91:339-41. 27. Bray PF, Bloomer LC, Salmon VC, Bagley MH, Larsen PD. Epstein-Barr virus infection and antibody synthesis in patients with multiple sclerosis. Archives of Neurology 1983;40:406-8. 28. Sumaya CV, Myers LW, Ellison GW. Epstein-Barr virus antibodies in multiple sclerosis. Archives of Neurology 1980;37:94-6. 29. Fraser KB, Haire M, Millar JH, McCrea S. Increased tendency to spontaneous in vitro lymphocyte transformation in clinically active multiple sclerosis. Lancet 1979;2 :175-6. 134 30. Wandinger K, Jabs W, Siekhaus A, Bubel S, Trillenberg P, Wagner H et al. Association between clinical disease activity and Epstein-Barr virus reactivation in MS [see comments]. Neurology 2000;55:178-84. 31. Hay KA,.Tenser RB. Leukotropic herpesviruses in multiple sclerosis. Multiple Sclerosis 2000;6:66-8. 32. Christensen T, Tonjes RR, zur MJ, Boller K, Moller-Larsen A. Reverse transcriptase activity and particle production in B lymphoblastoid cell lines established from lymphocytes of patients with multiple sclerosis. AIDS Research & Human Retroviruses 1999;15:285-91. 33. Hennig H, Wessel K, Sondermeijer P, Kirchner H, Wandinger KP. Lack of evidence for Marek's disease virus genomic sequences in leukocyte DNA from multiple sclerosis patients in Germany. Neuroscience Letters 1998;250:138-40. 34. Martin C, Enbom M, Soderstrom M, Fredrikson S, Dahl H, Lycke J et al. Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis. Acta Neurologica Scandinavica 1997;95:280-3. 35. Ferrante P, Omodeo-Zorini E, Zuffolato MR, Mancuso R, Caldarelli S, R et al. Human T-cell lymphotropic virus tax and Epstein-Barr virus DNA in peripheral blood of multiple sclerosis patients during acute attack. Acta Neurologica Scandinavica 1997;Supplementum. 169:79-85. 36. Sanders VJ, Felisan S, Waddell A, Tourtellotte WW. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. Journal of Neurovirology 1996;2:249-58. 37. Munch M, Moller-Larsen A, Christensen T, Morling N, Hansen HJ, Haahr S. B lymphoblastoid cell lines from multiple sclerosis patients and a healthy control producing a putative new human retrovirus and Epstein-Barr virus. Multiple Sclerosis 1995;1:78-81. 38. Hilton DA, Love S, Fletcher A, Pringle JH. Absence of Epstein-Barr virus RNA in multiple sclerosis as assessed by in situ hybridisation. Journal of Neurology, Neurosurgery & Psychiatry 1994;57:975-6. 39. Haahr S, Sommerlund M, Christensen T, Jensen AW, Hansen HJ, Moller-Larsen A. A putative new retrovirus associated with multiple sclerosis and the possible involvement of Epstein-Barr virus in this disease. Annals of the New York Academy of Sciences 1994;724:148-56. 40. Bray PF, Luka J, Bray PF, Culp KW, Schlight JP. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 1992;42:1798-804. 41. Marrie RA, Wolfson C, Sturkenboom MC, Gout O, Heinzlef O, Roullet E et al. Multiple sclerosis and antecedent infections: a case-control study. Neurology 2000;54:230710. 42. Jensen MK, Koch-Henriksen N, Johansen P, Varming K, Christiansen CB, Knudsen F. EBV-positive primary central nervous system lymphomas in monozygote twins with common variable immunodeficiency and suspected multiple sclerosis. Leukemia & Lymphoma 1997;28:187-93. 135 43. Ko FJ, Chiang CH, Jong YJ, Chang CH. Neuromyelitis optica (Devic's disease) report of one case. Chung-Hua Min Kuo Hsiao Erh Ko i Hsueh Hui Tsa Chih 1989;30:428-31. 44. Shaw CM,.Alvord EC, Jr. Multiple sclerosis beginning in infancy. Journal of Child Neurology 1987; 2:252-6. 45. Richardson JR. Demyelinating disease: association with Epstein-Barr virus [letter]. Archives of Neurology 1984;41:14-5. 46. Warner HB,.Carp RI. Multiple sclerosis and Epstein-Barr virus [letter]. Lancet 1981;2 :1290. Additional Epsten Barr virus papers 1. Culora GA,.Moore IE. Kawasaki disease, Epstein-Barr virus and coronary artery aneurysMS. Journal of Clinical Pathology 1997;50:161-3. 2. Nakagawa A, Ito M, Iwaki T, Yatabe Y, Asai J, Hayashi K. Chronic active EpsteinBarr virus infection with giant coronary aneurysMS. American Journal of Clinical Pathology 1996;105:733-6. 3. Muso E, Fujiwara H, Yoshida H, Hosokawa R, Yashiro M, Hongo Y et al. EpsteinBarr virus genome-positive tubulointerstitial nephritis associated with Kawasaki disease-like coronary aneurysMS. Clinical Nephrology 1993;40:7-15. 4. Kikuta H, Sakiyama Y, Matsumoto S, Hamada I, Yazaki M, Iwaki T et al. Detection of Epstein-Barr virus DNA in cardiac and aortic tissues from chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysMS. Journal of Pediatrics 1993;123:90-2. 5. Takano Y, Manabe H, Aoyama Y, Nakamichi N, Matsumura T, Kurata T. Measles associated with coronary arteritis. Virchows Archiv - A, Pathological Anatomy & Histopathology 1990;416:271-6. HERPES SIMPLEX VIRUS Occupational relevance 1. Fatal Cercopithecine herpesvirus 1 (B virus) infection following a mucocutaneous exposure and interim recommendations for worker protection. MMWR - Morbidity & Mortality Weekly Report 1083;47:1073-6. 2. Amir J, Nussinovitch M, Kleper R, Cohen HA, Varsano I. Primary herpes simplex virus type 1 gingivostomatitis in pediatric personnel. Infection 1997;25:310-2. 3. Baker DA. Herpes simplex virus infections. [Review] [21 refs]. Current Opinion in Obstetrics & Gynecology 1992;4:676-81. 4. Bek M, Koppl H, Schwarzkopf G, Freudenberg N. Weil's disease and necrotizing herpes simplex pneumonia as the cause of death in a 39-year-old sewerage worker. Pathologe 1996;17:471-6. 136 5. Freifeld AG, Hilliard J, Southers J, Murray M, Savarese B, Schmitt JM et al. A controlled seroprevalence survey of primate handlers for evidence of asymptomatic herpes B virus infection. Journal of Infectious Diseases 1995;171:1031-4. 6. Gill MJ, Arlette J, Buchan K. Herpes simplex virus infection of the hand. A profile of 79 cases. American Journal of Medicine 1988;84:89-93. 7. Herbert AM, Bagg J, Walker DM, Davies KJ, Westmoreland, D. Seroepidemiology of herpes virus infections among dental personnel. Journal Of Dentistry 1995;23:339-42. 8. Holmes GP, Hilliard JK, Klontz KC, Rupert AH, Schindler CM, Parrish E et al. B virus (Herpesvirus simiae) infection in humans: epidemiologic investigation of a cluster [see comments]. Annals of Internal Medicine 1990;112:833-9. 9. Jainkittivong A,.Langlais RP. Herpes B virus infection. [Review] [30 refs]. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontics 1998;85:399-403. 10. Kleiman MB, Schreiner RL, Eitzen H. Oral herpesvirus infection in nursery personnel: Infection control policy. Pediatrics 1982;70. 11. Merchant VA. Herpes simplex virus infection: an occupational hazard in dental practice. Journal of Michigan Dental Association 1982;64:199-203. 12. Nguyen C,.Lalonde RG. Risk of occupational exposure to Herpesvirus simiae (B virus) in Quebec. CMAJ 1990;143:1203-6. 13. Rames S, Folkmar T, Roed-Petersen B. Herpes simplex as a possibly occupational disease in dentists of the County of Aarhus, Denmark. Acta Dermato-Venereologica 1984;64:163-5. 14. Amir J, Nussinovitch M, Kleper R, Cohen HA, Varsano I. Primary herpes simplex virus type 1 gingivostomatitis in pediatric personnel. Infection 1997;25:310-2. HERPES SIMPLEX VIRUS AND ALZHEIMER'S DISEASE Herpes Simplex Virus and Alzheimer's Disease – medline search 1. Federoff HJ. An infectious conspiracy: the case for HSV-1 and APOEepsilon4 in Alzheimer's disease [comment]. [Review] [5 refs]. Neurobiology of Aging 1999;20:467-8. 2. Dobson CB,.Itzhaki RF. Herpes simplex virus type 1 and Alzheimer's disease [see comments]. [Review] [91 refs]. Neurobiology of Aging 1999;20:457-65. 3. Leissring MA, Sugarman MC, LaFerla FM. Herpes simplex virus infections and Alzheimer's disease. Implications for drug treatment and immunotherapy. [Review] [31 refs]. Drugs & Aging 1998;13:193-8. 4. Itzhaki RF,.Lin WR. Herpes simplex virus type I in brain and the type 4 allele of the apolipoprotein E gene are a combined risk factor for Alzheimer's disease. [Review] [42 refs]. Biochemical Society Transactions 1998;26:273-7. 5. Shaw CM,.Alvord EC, Jr. Neuropathology of the limbic system. [Review] [47 refs]. Neuroimaging Clinics of North America 1997;7:101-42. 137 6. Garrard P, Perry R, Hodges JR. Disorders of semantic memory [editorial]. [Review] [52 refs]. Journal of Neurology, Neurosurgery & Psychiatry 1997;62:431-5. 7. Ball MJ, Lewis E, Haase AT. Detection of herpes virus genome in Alzheimer's disease by in situ hybridization: a preliminary study. Journal of Neural Transmission 1987;Supplementum. 24:219-25. 8. Haase AT, Lewis E, Wietgrefe S, Zupancic M, Diedrich J, Minnigan H et al. Speculations on the role of transmissible agents in the pathogenesis of Alzheimer's disease. Canadian Journal of Neurological Sciences 1986;13:449-51. 9. Schwab JJ. Psychiatric aspects of infectious diseases. [Review] [39 refs]. Current Psychiatric Therapies 1982;21:225-39. 10. Pascale A, Bhagavan S, Nelson TJ, Neve RL, McPhie DL, Etcheberrigaray R. Enhanced BK-induced calcium responsiveness in PC12 cells expressing the C100 fragment of the amyloid precursor protein. Brain Research 1999;Molecular Brain Research. 72:205-13. 11. Bursztajn S, DeSouza R, McPhie DL, Berman SA, Shioi J, Robakis NK et al. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. Journal of Neuroscience 1998;18:9790-9. 12. Glaser R,.Kiecolt-Glaser JK. Chronic stress modulates the virus-specific immune response to latent herpes simplex virus type 1. Annals of Behavioral Medicine 1997;19:78-82. 13. McPhie DL, Lee RKK, Eckman CB, Olstein DH, Durham SP, Yager D et al. Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains. Journal of Biological Chemistry 1997;272:24743-6. 14. Ibarreta D, Tao J, Parrilla R, Ayuso MS. Mutation analysis of chromosome 19 calmodulin (CALM3) gene in Alzheimer's disease patients. Neuroscience Letters 1997;229:157-60. 15. Itzhaki RF, Lin WR, Shang D, Wilcock GK, Faragher B, Jamieson GA. Herpes simplex virus type 1 in brain and risk of Alzheimer's disease [see comments]. Lancet 1997;349:241-4. 16. Shoji M, Kawarabayashi T, Sato M, Sasaki A, Matsubara E, Iizuka T et al. Systemic overexpression of a C-terminal fragment of human amyloid beta-protein precursor causes accumulation of Alzheimer beta-amyloid fibrils in pancreas of transgenic mice. Gerontology 1996;42 Suppl 1:48-56. 17. Johnstone EM, Oltersdorf T, Bales KR, Chaney MO, Santerre RF, Little SP. Expression of potentially amyloidogenic derivatives of the Alzheimer amyloid precursor protein in cultured 293 cells. Neuroscience Letters 1994;180:151-4. 18. Matsumoto A,.Fujiwara Y. Aberrant proteolysis of the beta-amyloid precursor protein in familial Alzheimer's disease lymphoblastoid cells. European Journal of Biochemistry 1993;217:21-7. 138 19. Ounanian A, Guilbert B, Renversez JC, Seigneurin JM, Avrameas S. Antibodies to viral antigens, xenoantigens, and autoantigens in Alzheimer's disease. Journal of Clinical Laboratory Analysis 1990;4:367-75. 20. Renvoize EB, Awad IO, Hambling MH. A sero-epidemiological study of conventional infectious agents in Alzheimer's disease. Age & Ageing 1987;16:311-4. 21. Sanders VJ, Felisan SL, Waddell AE, Conrad AJ, Schmid P, Swartz BE et al. Presence of herpes simplex DNA in surgical tissue from human epileptic seizure foci detected by polymerase chain reaction: preliminary study [see comments]. Archives of Neurology 1997;54:954-60. 22. Lin WR, Casas I, Wilcock GK, Itzhaki RF. Neurotropic viruses and Alzheimer's disease: a search for varicella zoster virus DNA by the polymerase chain reaction. Journal of Neurology, Neurosurgery & Psychiatry 1997;62:586-9. 23. Lin WR, Shang D, Itzhaki RF. Neurotropic viruses and Alzheimer disease. Interaction of herpes simplex type 1 virus and apolipoprotein E in the etiology of the disease. Molecular & Chemical Neuropathology 1996;28:135-41. 24. Jamieson GA, Maitland NJ, Wilcock GK, Yates CM, Itzhaki RF. Herpes simplex virus type 1 DNA is present in specific regions of brain from aged people with and without senile dementia of the Alzheimer type. Journal of Pathology 1992;167:365-8. 25. Jamieson GA, Maitland NJ, Craske J, Wilcock GK, Itzhaki RF. Detection of herpes simplex virus type 1 DNA sequences in normal and Alzheimer's disease brain using polymerase chain reaction. Biochemical Society Transactions 1991;19:122S. 26. Jamieson GA, Maitland NJ, Wilcock GK, Craske J, Itzhaki RF. Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains. Journal of Medical Virology 1991;33:224-7. 27. Deatly AM, Haase AT, Fewster PH, Lewis E, Ball MJ. Human herpes virus infections and Alzheimer's disease. Neuropathology & Applied Neurobiology 1990;16:213-23. 28. Walker DG, O'Kusky JR, McGeer PL. In situ hybridization analysis for herpes simplex virus nucleic acids in Alzheimer disease. Alzheimer Disease & Associated Disorders 1989;3:123-31. 29. Taylor GR,.Crow TJ. Viruses in human brains: a search for cytomegalovirus and herpes virus 1 DNA in necropsy tissue from normal and neuropsychiatric cases. Psychological Medicine 1986;16:289-95. 30. Taylor GR, Crow TJ, Markakis DA, Lofthouse R, Neeley S, Carter GI. Herpes simplex virus and Alzheimer's disease: a search for virus DNA by spot hybridisation. Journal of Neurology, Neurosurgery & Psychiatry 1984;47:1061-5. 31. Mann DM, Tinkler AM, Yates PO. Neurological disease and herpes simplex virus. An immunohistochemical study. Acta Neuropathologica 1983;60:24-8. 32. Itzhaki RF, Wozniak M, Dobson C, Lin WR. ApoE-viral interactions [letter; comment]. Nature Medicine 1998;4:1344. 33. Corder E, Lannfelt L, Mulder M. Apolipoprotein E and herpes simplex virus 1 in Alzheimer's disease [letter; comment]. Lancet 1998;352:1312-3. 139 34. Rieckmann P, Turner T, Kligannon P, Steinhoff BJ. Telencephalin as an indicator for temporal-lobe dysfunction [letter]. Lancet 1998;352:370-1. 35. Itzhaki RF, Lin WR, Wilcock GK, Faragher B. HSV-1 and risk of Alzheimer's disease [letter; comment] [see comments]. Lancet 1998;352:238. 36. Beffert U, Bertrand P, Champagne D, Gauthier S, Poirier J. HSV-1 in brain and risk of Alzheimer's disease [letter; comment] [see comments]. Lancet 1998;351:1330-1. 37. Itabashi S, Arai H, Matsui T, Higuchi S, Sasaki H. Herpes simplex virus and risk of Alzheimer's disease [letter; comment]. Lancet 1997;349:1102. 38. Latchman DS. Herpes simplex virus and risk of Alzheimer's disease [letter; comment]. Lancet 1997; 349:1101-2. 39. Ball MJ, Kaye JA, Steiner I. Neocortical temporal lobe sclerosis masquerading as Alzheimer dementia: does herpes virus encephalopathy protect against Alzheimer's disease? Clinical Neuropathology 1997;16:1-12. 40. Jack DB. Herpes simplex virus and Alzheimer's disease [news]. Molecular Medicine Today 1996;2:270. 41. Lin WR, Shang D, Wilcock GK, Itzhaki RF. Alzheimer's disease, herpes simplex virus type 1, cold sores and apolipoprotein E4. Biochemical Society Transactions 1995;23:594S. 42. Zachhuber C, Leblhuber F, Jellinger K, Bancher C, Tilz GP, Binder L. [Necrotizing herpes simplex encephalitis as the cause of a progressive dementia syndrome]. [Review] [19 refs] [German]. Deutsche Medizinische Wochenschrift 1995;120:1278-82. 43. Mauri A, Daum I, Sartori G, Riesch G, Birbaumer N. Category-specific semantic impairment in Alzheimer's disease and temporal lobe dysfunction: a comparative study. Journal of Clinical & Experimental Neuropsychology 1994;16:689-701. 44. Wong VC, Wong MT, Ng TH, Chang CM, Fung CF. Unusual case of Kluver-Bucy syndrome in a Chinese boy. Pediatric Neurology 1991;7:385-8. 45. Roberts GW. Herpesvirus in Alzheimer's disease: a refutation [letter]. Archives of Neurology 1987;44:12. 46. Gannicliffe A, Sutton RN, Itzhaki RF. Viruses, brain and immunosuppression. Psychological Medicine 1986;16:247-9. 47. Roberts GW, Taylor GR, Carter GI, Johnson JA, Bloxham C, Brown R et al. Herpes simplex virus: a role in the aetiology of Alzheimer's disease? [letter]. Journal of Neurology, Neurosurgery & Psychiatry 1986;49:216. 48. Ball MJ. Herpesvirus in the hippocampus as a cause of Alzheimer's disease [letter]. Archives of Neurology 1986;43:313. 49. Esiri MM. Viruses and Alzheimer's disease [letter]. Journal of Neurology, Neurosurgery & Psychiatry 1982;45:759-60. 140 50. Ball MJ. "Limbic predilection in Alzheimer dementia: is reactivated herpesvirus involved?". Canadian Journal of Neurological Sciences 1982;9:303-6. 51. Mann DM, Yates PO, Davies JS, Hawkes J. Viruses, Parkinsonism and Alzheimer's disease [letter]. Journal of Neurology, Neurosurgery & Psychiatry 1981;44:651. 52. Middleton PJ, Petric M, Kozak M, Rewcastle NB, McLachlan DR. Herpes-simplex viral genome and senile and presenile dementias of Alzheimer and Pick [letter]. Lancet 1980;1:1038. 53. Elizan T S, Casals J. The viral hypothesis in parkinsonism. Journal of Neural Transmission. Supplementum;19:75-88 Herpes Simplex Virus and Alzheimer's Disease search - science citatation index 1. Itzhaki RF. Possible factors in the etiology of Alzheimer's-disease. Molecular Neurobiology 1994;9:1-13. 2. Lin WR, Graham J, MacGowan SM, Wilcock GK, Itzhaki RF. Alzheimer's disease, herpes virus in brain, apolipoprotein E4 and herpes labialis. Alzheimer's Reports 1998; 1: 173 8. Other Viruses and Alzheimer's Disease Epstein Barr Virus 1. Xu S,.Gaskin F. Increased incidence of anti-beta-amyloid autoantibodies secreted by Epstein-Barr virus transformed B cell lines from patients with Alzheimer's disease. Mechanisms of Ageing & Development 1997;94:213-22. 2. Yao XL, Jenkins EC, Wisniewski HM. Effect of aluminum chloride on mitogenesis, mitosis, and cell cycle in human short-term whole blood cultures: lower concentrations enhance mitosis. Journal of Cellular Biochemistry 1994;54:473-7. Cytomegalovirus 1. Renvoize EB, Awad IO, Hambling MH. A sero-epidemiological study of conventional infectious agents in Alzheimer's disease. Age & Ageing 1987;16:311-4. 2 Renvoize EB,.Hambling MH. Cytomegalovirus infection and Alzheimer's disease. Age & Ageing 1984;13:205-9. 3. Taylor GR,.Crow TJ. Viruses in human brains: a search for cytomegalovirus and herpes virus 1 DNA in necropsy tissue from normal and neuropsychiatric cases. Psychological Medicine 1986;16:289-95. 4. Renvoize EB, Hambling MH, Pepper MD, Rajah SM. Possible association of Alzheimer's disease with HLA-BW15 and cytomegalovirus infection [letter]. Lancet 1979;1:1238. 141 Varicella Zoster virus 1. Lin WR, Casas I, Wilcock GK, Itzhaki RF. Neurotropic viruses and Alzheimer's disease: a search for varicella zoster virus DNA by the polymerase chain reaction. Journal of Neurology, Neurosurgery & Psychiatry 1997;62:586-9. 2. Lin WR, Shang D, Itzhaki RF. Neurotropic viruses and Alzheimer disease. Interaction of herpes simplex type 1 virus and apolipoprotein E in the etiology of the disease. Molecular & Chemical Neuropathology 1996;28:135-41. 3. Ball MJ, Kaye JA, Steiner I. Neocortical temporal lobe sclerosis masquerading as Alzheimer dementia: does herpes virus encephalopathy protect against Alzheimer's disease? Clinical Neuropathology 1997;16:1-12. HERPES SIMPLEX VIRUS AND CORONARY HEART DISEASE Herpes Simplex Virus and Coronary Heart Disease – medline search 1. Fong IW. Emerging relations between infectious diseases and coronary artery disease and atherosclerosis. [Review] [95 refs]. CMAJ 2000;163:49-56. 2. Leinonen M,.Saikku P. Infections and atherosclerosis. [Review] [118 refs]. Scandinavian Cardiovascular Journal 2000;34:12-20. 3. Sinha N,.Garg N. Role of infections in the pathogenesis of atherosclerotic coronary artery disease: past, present and future. [Review] [49 refs]. Indian Heart Journal 2000;52:7985. 4. Muhlestein JB. Chronic infection and coronary artery disease. [Review] [129 refs]. Medical Clinics of North America 2000;84:123-48. 5. Vercellotti G. Infectious agents that play a role in atherosclerosis and vasculopathies. What are they? What do we do about them? Canadian Journal of Cardiology 1999;15 Suppl B:13B-5B. 6. Libby P, Egan D, Skarlatos S. Roles of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. [Review] [91 refs]. Circulation 1997;96:4095-103. 7. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? [see comments]. [Review] [62 refs]. Lancet 1997;350:430-6. 8. Ellis RW. Infection and coronary heart disease. [Review] [44 refs]. Journal of Medical Microbiology 1997;46:535-9. 9. Sorlie PD, Nieto FJ, Adam E, Folsom AR, Shahar E, Massing M. A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study. Archives of Internal Medicine 2000;160:2027-32. 10. Carlsson J, Miketic S, Brom J, Ross R, Bachmann H, Tebbe U. Prior cytomegalovirus, Chlamydia pneumoniae or Helicobacter pylori infection and the risk of restenosis after percutaneous transluminal coronary angioplasty. International Journal of Cardiology 2000;73:165-71. 142 11. Roivainen M, Viik-Kajander M, Palosuo T, Toivanen P, Leinonen M, Saikku et al. Infections, inflammation, and the risk of coronary heart disease. Circulation 2000;101:252-7. 12. Lindberg G, Rastam L, Lundblad A, Sorlie PD, Folsom AR. The association between serum sialic acid and asymptomatic carotid atherosclerosis is not related to antibodies to herpes type viruses or Chlamydia pneumoniae. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. International Journal of Epidemiology 1997;26:1386-91. 13. Minick CR, Fabricant CG, Fabricant J, Litrenta MM. Atheroarteriosclerosis induced by infection with a herpesvirus. American Journal of Pathology 1979;96:673-706. 14. Raza-Ahmad A, Klassen GA, Murphy DA, Sullivan JA, Kinley CE, Landymore et al. Evidence of type 2 herpes simplex infection in human coronary arteries at the time of coronary artery bypass surgery. Canadian Journal of Cardiology 1995;11:1025-9. 15. Constans J, Seigneur M, Blann A, Conri C. Chronic infections and coronary heart disease [letter; comment]. Lancet 1997;350:1030. HERPES SIMPLEX VIRUS AND MULTIPLE SCLEROSIS Herpes Simplex Virus and Multiple Sclerosis – medline search 1. Martin JR. Herpes simplex virus types 1 and 2 and multiple sclerosis. Lancet 1981;2:777-81. 2. Perron H, Suh M, Lalande B, Gratacap B, Laurent A, Stoebner P et al. Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis. Journal of General Virology 1993;74:65-72. 3 de Silva SM,.McFarland HF. Multiple sclerosis patients have reduced HLA class II restricted cytotoxic responses specific for both measles and herpes virus. Journal of Neuroimmunology 1991;35:219-26. 4. Itoyama Y, Sekizawa T, Openshaw H, Kogure K, Goto I. Early loss of astrocytes in herpes simplex virus-induced central nervous system demyelination. Annals of Neurology 1991;29:285-92. 5. Bergstrom T, Alestig K, Svennerholm B, Horal P, Skoldenberg B, Vahlne A. Neurovirulence of herpes simplex virus types 1 and 2 isolates in diseases of the central nervous system. European Journal of Clinical Microbiology & Infectious Diseases 1990;9:751-7. 6. Riikonen R,.Meurman O. Long-term persistence of intrathecal viral antibody responses in postinfectious diseases of the central nervous system and in Rett syndrome. Neuropediatrics 1989;20:215-9. 7. Kastrukoff LF, Lau AS, Kim SU. Multifocal CNS demyelination following peripheral inoculation with herpes simplex virus type 1. Annals of Neurology 1987;22:52-9. 8. Vahlne A, Edstrom S, Hanner P, Andersen O, Svennerholm B, Lycke E. Possible association of herpes simplex virus infection with demyelinating disease. Scandinavian Journal of Infectious Diseases - Supplementum 1985;47:16-21. 143 9. Ziola B,.Hader WJ. Adherent cells suppress measles and herpes simplex I virus induced blastogenesis of multiple sclerosis lymphocytes. Journal of Neuroimmunology 1985;7:315-30. 10 Martin JR. Intra-axonal virus in demyelinative lesions of experimental herpes simplex type 2 infection. Journal of the Neurological Sciences 1984;63:63-74. 11. Flynn TE,.Martin JR. Topography of remyelinated chronic spinal cord lesions in herpes simplex virus type 2 infections of mice. Journal of the Neurological Sciences 1983;61:327-39. 12. Rabinowitz SG, Day ED, Paterson PY, Koenig H. Endogenous myelin basic protein serum factors (MBP-SFS) and anti-MBP antibodies in a patient with post-herpes simplex virus acute disseminated encephalomyelitis. Journal of the Neurological Sciences 1983;60:393-400. 13. Haahr S, Moller-Larsen A, Pedersen E. Immunological parameters in multiple sclerosis patients with special reference to the herpes virus group. Clinical & Experimental Immunology 1983;51:197-206. 14. Tovell DR, McRobbie IA, Warren KG, Tyrrell DL. Interferon production by lymphocytes from multiple sclerosis and non-MS patients. Neurology 1983;33:640-3. 15. Salonen R, Ilonen J, Reunanen M, Salmi A. Defective production of interferon-alpha associated with HLA-DW2 antigen in stable multiple sclerosis. Journal of the Neurological Sciences 1982;55:197-206. 16. Martin JR. Spinal cord and optic nerve demyelination in experimental herpes simplex virus type 2 infection. Journal of Neuropathology & Experimental Neurology 1982;41:25366. 17. Myhr KM, Riise T, Barrett-Connor E, Myrmel H, Vedeler C, Gronning M et al. Altered antibody pattern to Epstein-Barr virus but not to other herpesviruses in multiple sclerosis: a population based case-control study from western Norway. Journal of Neurology, Neurosurgery & Psychiatry 1998;64:539-42. 18. Baig S, Olsson O, Olsson T, Love A, Jeansson S, Link H. Cells producing antibody to measles and herpes simplex virus in cerebrospinal fluid and blood of patients with multiple sclerosis and controls. Clinical & Experimental Immunology 1989;78:390-5. 19. Mathiesen T, von Holst H, Fredrikson S, Wirsen G, Hederstedt B, Norrby et al. Total, anti-viral, and anti-myelin IgG subclass reactivity in inflammatory diseases of the central nervous system. Journal of Neurology 1989;236:238-42. 20. Salmi AA, Hyypia T, Ilonen J, Reunanen M, Remes M. Production of viral antibodies in vitro by CSF cells from mumps meningitis and multiple sclerosis patients. Journal of the Neurological Sciences 1989;90:315-24. 21. Ferrante P, Castellani P, Barbi M, Bergamini F. The Italian Cooperative Multiple Sclerosis case-control study: preliminary results on viral antibodies. Italian Journal of Neurological Sciences 1987;Suppl 6:45-50. 144 22. Caputo D, Ferrante P, Zaffaroni M, Ghezzi A, Cazzullo CL. Longitudinal survey of T-lymphocytes and viral antibodies in MS patients. Italian Journal of Neurological Sciences 1987;Suppl 6:53-6. 23. Cooperative Italian study on multiple sclerosis and risk factors: a case-control study. The Coordinating Center and the Neurological Centers of the Cooperative Group. Italian Journal of Neurological Sciences 1987;Suppl 6:17-20. 24. Coyle PK,.Sibony PA. Viral specificity of multiple sclerosis tear immunoglobulins. Journal of Neuroimmunology 1987;14:197-203. 25. Gerhard W, Taylor A, Sandberg-Wollheim M, Koprowski H. Longitudinal analysis of three intrathecally produced immunoglobulin subpopulations in an MS patient. Journal of Immunology 1985;134:1555-60. 26. Coyle PK,.Procyk-Dougherty Z. Multiple sclerosis immune complexes: an analysis of component antigens and antibodies. Annals of Neurology 1984;16:660-7. 27. Isager H, Cohn J, Hesse J, Vestergaard BF. Antibodies to herpes simplex and Epstein-Barr viruses in Faroese children: association with sibship size, height and age. Acta Pathologica, Microbiologica, et Immunologica Scandinavica - Section B, Microbiology 1983;91:339-41. 28. Salmi A, Reunanen M, Ilonen J, Panelius M. Intrathecal antibody synthesis to virus antigens in multiple sclerosis. Clinical & Experimental Immunology 1983;52:241-9. 29. Reunanen M, Ilonen J, Arnadottir T, Ahonen A, Salmi A. Mitogen and antigen stimulation of multiple sclerosis cerebrospinal fluid lymphocytes in vitro. Journal of the Neurological Sciences 1983;58:211-21. 30. Rostrom B. Antibodies against viruses and structural brain components in oligoclonal IgG obtained from multiple sclerosis brain. Journal of Neurology 1982;226:255-63. 31. Visscher BR, Sullivan CB, Detels R, Madden DL, Sever JL, Terasaki PI et al. Measles antibody titers in multiple sclerosis patients and HLA-matched and unmatched siblings. Neurology 1981;31:1142-5. 32. Ilonen J, Reunanen M, Salmi A, Tiilikainen A. Lymphocyte blast transformation responses and viral antibodies in relation to HLA antigens in multiple sclerosis. Journal of the Neurological Sciences 1981;49:117-33. 33. Sagar HJ, Allonby ID, Hughes P. Cell-mediated immunity to viral antigens and tuberculin in multiple sclerosis. Acta Neurologica Scandinavica 1981;63:81-98. 34. Vartdal F, Vandvik B, Norrby E. Viral and bacterial antibody responses in multiple sclerosis. Annals of Neurology 1980;8:248-55. 35. Forghani B, Cremer NE, Johnson KP, Fein G, Likosky WH. Comprehensive viral immunology of multiple sclerosis. III. Analysis of CSF antibodies by radioimmunoassay. Archives of Neurology 1980;37:616-9. 36. Cremer NE, Johnson KP, Fein G, Likosky WH. Comprehensive viral immunology of multiple sclerosis. II. Analysis of serum and CSF antibodies by standard serologic methods. Archives of Neurology 1980;37:610-5. 145 37. Nordal HJ, Vandvik B, Norrby E. Multiple sclerosis: local synthesis of electrophoretically restricted measles, rubella, mumps and herpes simplex virus antibodies in the central nervous system. Scandinavian Journal of Immunology 1978;7:473-9. 38. Fuccillo DA, Madden DL, Castellano GA, Uhlig L, Traub RG, Mattson J et al. Multiple sclerosis: cellular and humoral immune responses to several viruses. Neurology 1978;28:613-5. 39. Martin C, Enbom M, Soderstrom M, Fredrikson S, Dahl H, Lycke J et al. Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis. Acta Neurologica Scandinavica 1997;95:280-3. 40. Dybwad A, Flrre O, Sioud M. Probing for cerebrospinal fluid antibody specificities by a panel of random peptide libraries. Autoimmunity 1997;25:85-9. 41. Ferrante P, Omodeo-Zorini E, Zuffolato MR, Mancuso R, Caldarelli S, R et al. Human T-cell lymphotropic virus tax and Epstein-Barr virus DNA in peripheral blood of multiple sclerosis patients during acute attack. Acta Neurologica Scandinavica 1997;Supplementum. 169:79-85. 42. Sanders VJ, Felisan S, Waddell A, Tourtellotte WW. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. Journal of Neurovirology 1996;2:249-58. 43. Sanders VJ, Waddell AE, Felisan SL, Li X, Conrad AJ, Tourtellotte WW. Herpes simplex virus in postmortem multiple sclerosis brain tissue [see comments]. Archives of Neurology 1996;53:125-33. 44. Baringer JR,.Pisani P. Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction [see comments]. Annals of Neurology 1994;36:823-9. 45. Nicoll JA, Kinrade E, Love S. PCR-mediated search for herpes simplex virus DNA in sections of brain from patients with multiple sclerosis and other neurological disorders. Journal of the Neurological Sciences 1992;113:144-51. 46. Aulakh GS, Albrecht P, Tourtellotte WW. Search for cytomegalovirus and herpes simplex virus genetic information in multiple sclerosis. Neurology 1980;30:530-2. 47. Martin JR, Holt RK, Webster HD. Herpes-simplex-related antigen in human demyelinative disease and encephalitis. Acta Neuropathologica 1988;76:325-37 48. Warren KG, Devlin M, Gilden DH, Wroblewska Z, Koprowski H, Brown SM et al. Herpes simplex virus latency in patients with multiple sclerosis, lymphoma and normal humans. IARC Scientific Publications 1978;765-8. 49 Puccioni-Sohler M, Kitze B, Felgenhauer K, Graef I T, Lange P, Novis S, Reiber H, Vaz, B. The value of CSF analysis for the differential diagnosis of HTLV-I associated myelopathy and multiple sclerosis. Arquivos de Neuro-Psiquiatria 1995;53(4): 760-5. 50. Christensen T, Tonjes RR, zur MJ, Boller K, Moller-Larsen A. Reverse transcriptase activity and particle production in B lymphoblastoid cell lines established from lymphocytes of patients with multiple sclerosis. AIDS Research & Human Retroviruses 1999;15:285-91. 146 51. Monteyne P, Bureau JF, Brahic M. Viruses and multiple sclerosis. [Review] [38 refs]. Current Opinion in Neurology 1998;11:287-91. 52. Christensen T, Jensen AW, Munch M, Haahr S, Sorensen PD, Riemann H et al. Characterization of retroviruses from patients with multiple sclerosis. Acta Neurologica Scandinavica 1997;Supplementum. 169:49-58. 53. Munch M, Moller-Larsen A, Christensen T, Morling N, Hansen HJ, Haahr S. B lymphoblastoid cell lines from multiple sclerosis patients and a healthy control producing a putative new human retrovirus and Epstein-Barr virus. Multiple Sclerosis 1995;1:78-81. 54. Haahr S, Sommerlund M, Christensen T, Jensen AW, Hansen HJ, Moller-Larsen A. A putative new retrovirus associated with multiple sclerosis and the possible involvement of Epstein-Barr virus in this disease. Annals of the New York Academy of Sciences 1994;724:148-56. 55. Sommerlund M, Pallesen G, Moller-Larsen A, Hansen HJ, Haahr S. Retrovirus-like particles in an Epstein-Barr virus-producing cell line derived from a patient with chronic progressive myelopathy. Acta Neurologica Scandinavica 1993;87:71-6. 56. Perron H, Suh M, Lalande B, Gratacap B, Laurent A, Stoebner P et al. Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis. Journal of General Virology 1993;74:65-72. 57. Weiss RA. Retroviruses and human disease. [Review] [44 refs]. Journal of Clinical Pathology 1987;40:1064-9. 58. Karpas A, Malik K, Lida J. Studies of human retroviruses in relation to adult T-cell leukaemia, acquired immune deficiency syndrome, and multiple sclerosis. Archives of Virology 1987;95:237-49. 59. Ferrante P, Castellani P, Barbi M, Bergamini F. The Italian Cooperative Multiple Sclerosis case-control study: preliminary results on viral antibodies. Italian Journal of Neurological Sciences 1987;Suppl 6:45-50. 60. Caputo D, Ferrante P, Zaffaroni M, Ghezzi A, Cazzullo CL. Longitudinal survey of T-lymphocytes and viral antibodies in MS patients. Italian Journal of Neurological Sciences 1987;Suppl 6:53-6. 61. Haile R, Smith P, Read D, Nassim D, Warlow C, Russell WC. A study of measles virus and canine distemper virus antibodies, and of childhood infections in multiple sclerosis patients and controls. Journal of the Neurological Sciences 1982;56:1-10. 62. Appel MJ, Glickman LT, Raine CS, Tourtellotte WW. Canine viruses and multiple sclerosis. Neurology 1981;31:944-9. 63. Powell JA, Kano K, Milgrom F. Specificity of antibodies to Newcastle disease virus. International Archives of Allergy & Applied Immunology 1985;76:336-40. 64. Powell JA, Kano K, Milgrom F. Antibodies to Newcastle disease virus in various human diseases. International Archives of Allergy & Applied Immunology 1985;76:331-5. 147 VARICELLA ZOSTER VIRUS Occupational relevance 1. Hyams PJ, Stuewe MCS, Heitzer V. Herpes zoster causing varicella (chickenpox) in hospital employees: Cost of a casual attitude. American Journal of Infection Control 1984;12. 2. Alter SJ, Hammond JA, McVey CJ, Myers MG. Susceptibility to varicella-zoster virus among adults at high risk for exposure. Infection Control 1986;7. 3. Brunell PA, Taylor-Wiedeman J, Lievens AW. Varicella in day care centers. [Review] [16 refs]. Reviews of Infectious Diseases 1986;8:589-90. 4. Donowitz LG, Hunt EH, Pugh VG, Farr BM, Hendley JO. Comparison of historical and serologic immunity to varicella-zoster virus in 373 hospital employees. American Journal of Infection Control 1987;15:212-4. 5. Ferson MJ, Bell SM, Robertson PW. Determination and importance of varicella immune status of nursing staff in a children's hospital. Journal of Hospital Infection 1990;15:347-51. 6. Gallagher J, Quaid B, Cryan B. Susceptibility to varicella zoster virus infection in healthcare workers. Occupational Medicine (Oxford) 1996;46:289-92. 7. Grimsley LF, Jacobs RR, Perkins JL. Varicella-zoster virus susceptibility in day-care workers. Applied Occupational & Environmental Hygiene 1992;7:191-4. 8. Hofmann F, Nubling M, Tiller FW. Infections with the Varicella zoster virus Occupational and social-medical aspects. Arbeitsmedizin Sozialmedizin Umweltmedizin 1997;32:219-24. 9. Jackson LA, Stewart LK, Solomon SL, Boase J, Alexander ER, Heath JL et al. Risk of infection with hepatitis A, B or C, cytomegalovirus, varicella or measles among child care providers. Pediatric Infectious Disease Journal 1996;15:584-9. 10. Kader AA. Costs and benefits of varicella screening and vaccination for healthcare workers at a general hospital. Saudi Medical Journal 1999;20:939-41. 11. L'Ecuyer PB, Miller M, Winters K, Fraser VJ. Tuberculosis, hepatitis B, rubella, rubeola, and varicella infection and immunity among medical school employees. Infection Control & Hospital Epidemiology 1998;19:915-7. 12. Lewis DA, Jenks P, Gent AEM, Side L, Breuer J, Simini B et al. Varicella-zoster vaccination for healthcare workers [10]. Lancet 1994;343:1362-3. 13. Loomis SC. Varicella vaccination: An overview for the occupational health nurse. AAOHN Journal 1997; 45:592-5. 14. Lund J. Varicella zoster virus in the healthcare setting: Risk and management. AAOHN Journal 1993;41:369-73. 15. McKinney WP, Horowitz MM, Battiola RJ. Susceptibility of hospital-based healthcare personnel to varicella-zoster virus infections. American Journal of Infection Control 1989;17:26-30. 148 16. Murray A, Kangro HO, Heath RB. Screening hospital staff for antibodies to varicella zoster virus [letter]. Lancet 1990;336:192. 17. Nassar NT,.Touma HC. Brief report: susceptibility of Filipino nurses to the varicella zoster virus. Infection Control 1986;7:71-2. 18. Raguin G. Prophylaxis of varicella in pediatric staff. Medecine et Maladies Infectieuses1996;26:447-50. 19. Sawyer MH, Chamberlin CJ, Wu YN, Aintablian N, Wallace MR. Detection of varicella-zoster virus DNA in air samples from hospital rooMS. Journal of Infectious Diseases 1994;169:91-4. 20. Sayre MR,.Lucid EJ. Management of varicella-zoster virus exposed hospital employees. Annals of Emergency Medicine 1987;16. 21. Steele RW, Coleman MA, Fiser M, Bradsher RW. Varicella zoster in hospital personnel: Skin test reactivity to monitor susceptibility. Pediatrics 1982;70. 22. Venkitaraman AR,.John TJ. The epidemiology of varicella in staff and students of a hospital in the tropics. International Journal of Epidemiology 1984;13:502-5. 23. Weber DJ, Rutala WA, Hamilton H. Prevention and control of varicella-zoster infections in healthcare facilities. [Review] [104 refs]. Infection Control & Hospital Epidemiology 1996;17:694-705. VARICELLA ZOSTER AND MULTIPLE SCLEROSIS Varicella zoster and Multiple Sclerosis – medline search 1. Ross RT. The varicella-zoster virus and multiple sclerosis. [Review] [30 refs]. Journal of Clinical Epidemiology 1998;51:533-5. 2. Viel R. Multiple sclerosis and zoster encephalomyelitis: a probable common etiopathogenesis. [Review] [13 refs]. Advances in Experimental Medicine & Biology 1989;257 :289-91. 3. Ross RT, Nicolle LE, Cheang M. The varicella zoster virus: a pilot trial of a potential therapeutic agent in multiple sclerosis. Journal of Clinical Epidemiology 1997;50:63-8. 4. Haahr S, Moller-Larsen A, Pedersen E. Immunological parameters in multiple sclerosis patients with special reference to the herpes virus group. Clinical & Experimental Immunology 1983;51:197-206. 5. Reiber H, Ungefehr S, Jacobi C. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Multiple Sclerosis 1998;4:111-7. 6. Myhr KM, Riise T, Barrett-Connor E, Myrmel H, Vedeler C, Gronning M et al. Altered antibody pattern to Epstein-Barr virus but not to other herpesviruses in multiple sclerosis: a population based case-control study from western Norway. Journal of Neurology, Neurosurgery & Psychiatry 1998;64:539-42. 7. Felgenhauer K. Psychiatric disorders in the encephalitic form of multiple sclerosis. Journal of Neurology 1990;237:11-8. 149 8. Schadlich HJ, Karbe H, Felgenhauer K. The prevalence of locally-synthesized virus antibodies in various forms of multiple sclerosis. Journal of the Neurological Sciences 1987;80:343-9. 9. Chiodi F, Sunqvist VA, Link H, Norrby E. Viral IgM antibodies in serum and cerebrospinal fluid in patients with multiple sclerosis and controls. Acta Neurologica Scandinavica 1987;75:201-8. 10. Felgenhauer K, Schadlich HJ, Nekic M, Ackermann R. Cerebrospinal fluid virus antibodies. A diagnostic indicator for multiple sclerosis? Journal of the Neurological Sciences 1985;71:291-9. 11. Vartdal F,.Vandvik B. Multiple sclerosis: subclasses of intrathecally synthesized IgG and measles and varicella zoster virus IgG antibodies. Clinical & Experimental Immunology 1983;54:641-7. 12. Vartdal F,.Vandvik B. Characterization of classes of intrathecally synthesized antibodies by imprint immunofixation of electrophoretically separated sera and cerebrospinal fluids. Acta Pathologica, Microbiologica, et Immunologica Scandinavica - Section C, Immunology 1983;91:69-75. 13. Vartdal F,.Vandvik B. Multiple sclerosis. Electrofocused "bands" of oligoclonal CSF IgG do not carry antibody activity against measles, varicella-zoster or rotaviruses. Journal of the Neurological Sciences 1982;54:99-107. 14. Rostrom B. Antibodies against viruses and structural brain components in oligoclonal IgG obtained from multiple sclerosis brain. Journal of Neurology 1982;226:255-63. 15. Gudmundsdottir S. Multiple sclerosis and common viral infections in Iceland. Acta Pathologica et Microbiologica Scandinavica - Section B, Microbiology 1979;87:379-84. 16 Martin C, Enbom M, Soderstrom M, Fredrikson S, Dahl H, Lycke J et al. Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis. Acta Neurologica Scandinavica 1997;95:280-3. 17. Ferrante P, Omodeo-Zorini E, Zuffolato MR, Mancuso R, Caldarelli S, R et al. Human T-cell lymphotropic virus tax and Epstein-Barr virus DNA in peripheral blood of multiple sclerosis patients during acute attack. Acta Neurologica Scandinavica 1997;Supplementum. 169:79-85. 18. Sanders VJ, Felisan S, Waddell A, Tourtellotte WW. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. Journal of Neurovirology 1996;2:249-58. 19. Ross RT, Nicolle LE, Dawood MR, Cheang M, Feschuk C. Varicella zoster antibodies after herpes zoster, varicella and multiple sclerosis. Canadian Journal of Neurological Sciences 1997;24:137-9. 20. Puccioni-Sohler M, Kitze B, Felgenhauer K, Graef IT, Lange P, Novis S et al. The value of CSF analysis for the differential diagnosis of HTLV-I associated myelopathy and multiple sclerosis. Arquivos de Neuro-Psiquiatria 1995;53:760-5. 150 21. Felgenhauer K,.Reiber H. The diagnostic significance of antibody specificity indices in multiple sclerosis and herpes virus induced diseases of the nervous system. Clinical Investigator 1992;70:28-37. 22 Haahr S, Munch M, Christensen T, Moller-Larsen A, Hvas J. Cluster of multiple sclerosis patients from Danish community [letter]. Lancet 1997;349:923 23. MacGregor HS,.Latiwonk QI. Search for the origin of multiple sclerosis by first identifying the vector. Medical Hypotheses 1992;37:67-73. 24. McStreet GH, Elkunk RB, Latiwonk QI. Investigations of environmental conditions during cluster indicate probable vectors of unknown exogenous agent(s) of multiple sclerosis [letter]. Comparative Immunology, Microbiology & Infectious Diseases 1992;15:75-7. 25 Bachmann S,.Kesselring J. Multiple sclerosis and infectious childhood diseases. Neuroepidemiology 1998;17:154-60. 26. Ross RT,.Cheang M. Common infectious diseases in a population with low multiple sclerosis and varicella occurrence. Journal of Clinical Epidemiology 1997;50:337-9. 27. Riise T, Gronning M, Klauber MR, Barrett-Connor E, Nyland H, Albrektsen et al. Clustering of residence of multiple sclerosis patients at age 13 to 20 years in Hordaland, Norway. American Journal of Epidemiology 1991;133:932-9 28. Cooperative Italian study on multiple sclerosis and risk factors: a case-control study. The Coordinating Center and the Neurological Centers of the Cooperative Group. Italian Journal of Neurological Sciences 1987;Suppl 6:17-20. 29. Ragozzino MW,.Kurland LT. Epidemiologic investigation of the association between herpes zoster and multiple sclerosis. Neurology 1983;33:648-9. 30. Ross RT, Cheang M, Landry G, Klassen L, Doerksen K. Herpes zoster and multiple sclerosis. Canadian Journal of Neurological Sciences 1999;26:29-32. 31. Ross RT, Nicolle LE, Cheang M. Varicella zoster virus and multiple sclerosis in a utterite population. Journal of Clinical Epidemiology 1995;48:1319-24. 32. Ross RT,.Cheang M. Geographic similarities between varicella and multiple sclerosis: an hypothesis on the environmental factor of multiple sclerosis. [Review] [38 refs]. Journal of Clinical Epidemiology 1995;48:731-7. 33. Rosener M, Dichgans J, Martin R, HarMS F. Chickenpox and multiple sclerosis: a case report [letter]. Journal of Neurology, Neurosurgery & Psychiatry 1995;58:637-8. 34. Ahasan HA, Rafiqueuddin AK, Chowdhury MA, Azhar MA, Kabir F. Neuromyelitis optica (Devic's disease) following chicken pox. Tropical Doctor 1994;24:75-6. 35. al Deeb SM, Yaqub BA, Khoja WO. Devic's neuromyelitis optica and varicella [letter]. Journal of Neurology 1993;240:450-1. 36. Ross RT. Varicella and remission of multiple sclerosis [letter]. Lancet 1991;337:300. 37. De Keyser J. Herpes zoster and multiple sclerosis [letter]. International Journal of Epidemiology 1987;16:484-5. 151 38. Bruguier A, Ponsot G, Khouri-Dagher L, de Leersnyder H. [Neuromyelitis optica or Devic disease complicating chickenpox (author's transl)]. [French]. Archives Francaises de Pediatrie 1981;38:763-4. Varicella zoster and Multiple Sclerosis – science citation index search 1 Baum P, Hofmann J, Kuhn HJ, Grahmann F, Wagner A. Positive PCR of varicella tester in the CSF of two patients with multiple sclerosis. Nervenheilkunde 1999;18:567-70. 2 Souberbielle BE, Szawlowski PWS, Russell WC. Is there a case for a virus etiology in multiple-sclerosis. Scottish Medical Journal 1995;40:55-62. 3 Steinberg D. Does multiple sclerosis have a herpesvirus connection? Scientist 2000;14:16-7. PARVOVIRUS Occupational relevance 1. Adler SP, Manganello A-M, Koch WC, Hempfling SH, Best AM. Risk of human parvovirus B19 infections among school and hospital employees during endemic periods. Journal of Infectious Diseases 1993;168:361-8. 2. Cartter ML, Farley TA, Rosengren S, Quinn DL, Gillespie SM, Gary GW et al. Occupational risk factors for infection with parvovirus B19 among pregnant women. Journal of Infectious Diseases 1991;163:282-5. 3. Dowell SF, Torok TJ, Thorp JA, Hedrick J, Erdman DD, Zaki SR et al. Parvovirus B19 infection in hospital workers: Community or hospital acquisition? Journal of Infectious Diseases 1995;172:1076-9. 4. Gillespie SM, Cartter ML, Asch S, Rokos JB, Gary GW, Tsou CJ et al. Occupational risk of human parvovirus B19 infection for school and day-care personnel during an outbreak of erythema infectiosum. Journal of the American Medical Association 1990;263:2061-5. 5. Harger JH, Adler SP, Koch WC, Harger GF. Prospective evaluation of 618 pregnant women exposed to parvovirus B19: risks and symptoms. Obstetrics & Gynecology 1998;91:413-20. 6. Harrison J,.Jones CE. Human parvovirus B19 infection in healthcare workers. Occupational Medicine (Oxford) 1995;45:93-6. 7. Lohiya GS, Stewart K, Perot K, Widman R. Parvovirus B19 outbreak in a developmental center. American Journal of Infection Control 1995;23:373-6. 8. Pillay D, Patou G, Hurt S, Kibbler CC, Griffiths PD. Parvovirus-B19 outbreak in a childrens ward. Lancet 1992;339:107-9. 9. Ray SM, Erdman DD, Berschling JD, Cooper JE, Torok TJ, Blumberg HM. Nosocomial exposure to parvovirus B19: low risk of transmission to healthcare workers. Infection Control & Hospital Epidemiology 1997;18:109-14. 152 10. B19 Seng C, Watkins P, Morse D, Barrett SP, Zambon M, Andrews N et al. Parvovirus outbreak on an adult ward. Epidemiology & Infection 1994;113:345-53. 11. Valeur-Jensen AK, Pedersen CB, Westergaard T, Jensen IP, Lebech M, Andersen PK et al. Risk factors for parvovirus B19 infection in pregnancy. JAMA 1999;281:1099-105. PARVOVIRUS AND ANAEMIA Parvovirus and Anaemia – medline search 1. Elsacker-Niele AM,.Kroes AC. Human parvovirus B19: relevance in internal medicine [see comments]. [Review] [64 refs]. Netherlands Journal of Medicine 1999;54:22130. 2. Osaki M, Matsubara K, Iwasaki T, Kurata T, Nigami H, Harigaya H et al. Severe aplastic anemia associated with human parvovirus B19 infection in a patient without underlying disease. [Review] [16 refs]. Annals of Hematology 1999;78:83-6. 3. Cherry JD. Parvovirus infections in children and adults. [Review] [118 refs]. Advances in Pediatrics 1999;46:245-69. 4. Sabella C,.Goldfarb J. Parvovirus B19 infections. American Family Physician 1999;60:1455-60. 5. Erslev AJ,.Soltan A. Pure red-cell aplasia: a review. [Review] [98 refs]. Blood Reviews 1996;10:20-8. 6. Brown KE,.Young NS. Parvoviruses and bone marrow failure. [Review] [95 refs]. Stem Cells 1996;14:151-63. 7. Chinea B,.Ramirez Ronda CH. Infections caused by parvovirus B19. [Review] [26 refs]. Boletin - Asociacion Medica de Puerto Rico 1996;88:20-6. 8. Kerr JR. Parvovirus B19 infection. [Review] [222 refs]. European Journal of Clinical Microbiology & Infectious Diseases 1996;15:10-29. 9. Young NS. Parvovirus infection and its treatment. [Review] [31 refs]. Clinical & Experimental Immunology 1996;104 Suppl 1:26-30. 10. Brown K E and Young N S [Review] [40 refs]. Reviews in Medical Microbiolgy 1995;6(4):246-256. 11 Young NS. B19 parvovirus. [Review] [187 refs]. Baillieres Clinical Haematology 1995;8:25-56. 12. Dessypris EN. Aplastic anemia and pure red cell aplasia. [Review] [47 refs]. Current Opinion in Hematology 1994;1:157-61. 13. Kirchner JT. Erythema infectiosum and other parvovirus B19 infections. [Review] [45 refs]. American Family Physician 1994;50:335-41. 14. Mortimer PP. Human B19 parvovirus infection: an example of multiple pathogenic effects determined by differences in host susceptibility. [Review] [9 refs]. Memorias do Instituto Oswaldo Cruz 1992;87 Suppl 5:129-31. 153 15. Keeler ML. Human parvovirus B-19: not just a pediatric problem. [Review] [17 refs]. Journal of Emergency Medicine 1992;10:39-44. 16. Torok TJ. Parvovirus B19 and human disease. [Review] [167 refs]. Advances in Internal Medicine 1992;37:431-55. 17. Kumar ML. Human parvovirus B19 and its associated diseases. [Review] [96 refs]. Clinics in Perinatology 1991;18:209-25. 18. Inoue S, Kinra NK, Mukkamala SR, Gordon R. Parvovirus B-19 infection: aplastic crisis, erythema infectiosum and idiopathic thrombocytopenic purpura. Pediatric Infectious Disease Journal 1991;10:251-3. 19 Anderson LJ. Human parvovirus B19. [Review] [21 refs]. Pediatric Annals 512;19:509-10. 20 Frickhofen N,.Young NS. Persistent parvovirus B19 infections in humans. [Review] [64 refs]. Microbial Pathogenesis 1989;7:319-27. 21 Leads from the MMWR. Risks associated with human parvovirus B19 infection. [Review] [72 refs]. JAMA 1989;261:1406-8. 22. Risks associated with human parvovirus B19 infection. [Review] [72 refs]. MMWR Morbidity & Mortality Weekly Report 1993;38:81-8. 23. Schneider AP,.Naides SJ. Human parvovirus infection. [Review] [20 refs]. American Family Physician 1989;39:165-9. 24. Baranski BG,.Young NS. Autoimmune aspects of aplastic anemia. [Review] [43 refs]. In Vivo 1988;2:91-4. 25. Smith MA,.Ryan ME. Parvovirus infections. From benign to life-threatening. Review] [37 refs]. Postgraduate Medicine 131;84:127-8. 26. Thurn J. Human parvovirus B19: historical and clinical review. [Review] [69 refs]. Reviews of Infectious Diseases 1988;10:1005-11. 27. Young N. Hematologic and hematopoietic consequences of B19 parvovirus infection. [Review] [84 refs]. Seminars in Hematology 1988;25:159-72. 28 Gray ES. Human parvovirus infection. [Review] [11 refs]. Journal of Pathology 1987;153:310-2. 29 Anderson MJ. Human parvovirus infections. [Review] [35 refs]. Journal of Virological Methods 1987;17:175-81. 30. Anderson LJ. Role of parvovirus B19 in human disease. [Review] [103 refs]. Pediatric Infectious Disease Journal 1987;6:711-8. 31. Baranski B,.Young N. Hematologic consequences of viral infections. [Review] [156 refs]. Hematology - Oncology Clinics of North America 1987;1:167-83. 154 32. Kurtzman GJ, Ozawa K, Cohen B, Hanson G, Oseas R, Young NS. Chronic bone marrow failure due to persistent B19 parvovirus infection. New England Journal of Medicine 1987;317:287-94. 33. Listernick R. Parvovirus infections in childhood. Pediatric Dermatology 1986; 3: 435-8. 34. Blacklock HA,.Mortimer PP. Aplastic crisis and other effects of the human parvovirus infection. [Review] [63 refs]. Clinics in Haematology 1984;13:679-91. 35 Kerr JR, Curran MD, Moore JE, Murphy PG. Parvovirus B19 infection--persistence and genetic variation. Scandinavian Journal of Infectious Diseases 1995;27:551-7. 36. Green SW, Malkovska I, O'Sullivan MG, Brown KE. Rhesus and pig-tailed macaque parvoviruses: identification of two new members of the erythrovirus genus in monkeys. Virology 2000;269:105-12. 37. Yaegashi N, Niinuma T, Chisaka H, Uehara S, Moffatt S, Tada K et al. Parvovirus B19 infection induces apoptosis of erythroid cells in vitro and in vivo. Journal of Infection 1999;39:68-76. 38. Jones LP, Erdman DD, Anderson LJ. Prevalence of antibodies to human parvovirus B19 nonstructural protein in persons with various clinical outcomes following B19 infection. Journal of Infectious Diseases 1999;180:500-4. 39. Frickhofen N, Chen ZJ, Young NS, Cohen BJ, Heimpel H, Abkowitz JL. Parvovirus B19 as a cause of acquired chronic pure red cell aplasia. British Journal of Haematology 1994;87:818-24. 40. Kynaston JA, West NC, Reid MM. A regional experience of red cell aplasia [see comments]. European Journal of Pediatrics 1993;152:306-8. 41. Heegaard ED, Myhre J, Hornsleth A, Gundestrup M, Boye H. Parvovirus B19 infections in patients with chronic anemia. Haematologica 1997;82:402-5. 42. Rogers BB, Rogers ZR, Timmons CF. Polymerase chain reaction amplification of archival material for parvovirus B19 in children with transient erythroblastopenia of childhood. Pediatric Pathology & Laboratory Medicine 1996;16:471-8. 43 . Koduri PR. B19 virus: an update [editorial]. Organs 1998;21:309-11 International Journal of Artificial 44. A 19-year-old woman with severe anemia [clinical conference]. American Journal of Medicine 1998;104:200-9. 45 Chambers LA,.Rauck AM. Acute transient hemolytic anemia with a positive DonathLandsteiner test following parvovirus B19 infection. Journal of Pediatric Hematology/Oncology 1996;18:178-81. 46 Kerr JR, Curran MD, Moore JE, Coyle PV, Ferguson WP. Persistent parvovirus B19 infection [letter]. Lancet 1995;345:1118. 47. Baldus M, Moller M, Walter H, Brass H, Queisser W. A case of pure red cell aplasia: follow-up on different immunosuppressive regimens. Clinical Investigator 1994;72:1051-5. 155 48. Vigeant P, Menard HA, Boire G. Chronic modulation of the autoimmune response following parvovirus B19 infection. Journal of Rheumatology 1994;21:1165-7. 49 Kunimi M, Ishikawa K, Tsutsumi H, Hirai M, Kumakawa T, Mori M. Parvovirus infection and hemolytic anemia [letter]. American Journal of Hematology 1994;46:159-60. 50. Ramage JK, Hale A, Gane E, Cohen B, Boyle M, Mufti G et al. Parvovirus B19 induced red cell aplasia treated with plasmapheresis and immunoglobulin [letter]. Lancet 1994;343:667-8. 51. Murray JC, Gresik MV, Leger F, McClain KL. B19 parvovirus-induced anemia in a normal child. Initial bone marrow erythroid hyperplasia and response to intravenous immunoglobulin. American Journal of Pediatric Hematology-Oncology 1993;15:420-3. 52 Berman DS,.Wenglin BD. Chronic parvovirus infection? [letter; comment]. Clinical Infectious Diseases 1993;16:726. 53. Catton MG, Thomas SM, Blacklock HA, Croxson MC. Hypoplastic crisis with persistent arthralgia and prolonged parvovirus B19 viraemia detected by polymerase chain reaction [letter]. Australian & New Zealand Journal of Medicine 1993;23:216-7. 54. Faden H, Gary GW, Jr., Anderson LJ. Chronic parvovirus infection in a presumably immunologically healthy woman [see comments]. Clinical Infectious Diseases 1992;15:5957. 55. Gahr M, Pekrun A, Eiffert H. Persistence of parvovirus B19-DNA in blood of a child with severe combined immunodeficiency associated with chronic pure red cell aplasia. European Journal of Pediatrics 1991;150:470-2. 56. Graeve JA,.Elliott SC. Neurologic symptoms, iron deficiency anemia, and parvovirus infection [letter; comment]. Journal of Pediatrics 1991;118:830. 57. Belloy M, Morinet F, Blondin G, Courouce AM, Peyrol Y, Vilmer E. Erythroid hypoplasia due to chronic infection with parvovirus B19 [letter]. New England Journal of Medicine 1990;322:633-4. 58. Kurtzman G, Frickhofen N, Kimball J, Jenkins DW, Nienhuis AW, Young NS. Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy [see comments]. New England Journal of Medicine 1989;321:519-23. 59. Anderson LJ,.Torok TJ. Human parvovirus B19 [editorial; comment]. New England Journal of Medicine 1989;321:536-8. 60 Petty RE. Viruses and childhood arthritis. Annals of Medicine 1997;29:149-52. 61 Kingsley G. Microbial DNA in the synovium--a role in aetiology or a mere bystander? [comment] [see comments]. Lancet 1997;349:1038-9. 62 Soderlund M, von Essen R, Haapasaari J, Kiistala U, Kiviluoto O, Hedman et al. Persistence of parvovirus B19 DNA in synovial membranes of young patients with and without chronic arthropathy [see comments]. Lancet 1997;349:1063-5. 156 63 Kerr JR, Ferguson WP, Mcmillan SA, Bruce IN, Bell AL. Parvovirus B19 and acute joint swelling in rheumatoid arthritis patients [letter]. Annals of the Rheumatic Diseases 1996;55:648-9. 64 Speyer I, Breedveld FC, Dijkmans BA. Human parvovirus B19 infection is not followed by inflammatory joint disease during long term follow-up. A retrospective study of 54 patients. Clinical & Experimental Rheumatology 1998;16:576-8. 65 Foto F, Saag KG, Scharosch LL, Howard EJ, Naides SJ. Parvovirus B19-specific DNA in bone marrow from B19 arthropathy patients: evidence for B19 virus persistence. Journal of Infectious Diseases 1993;167:744-8. 66 Lopreiato JO,.Katona IM. Parvovirus B19-induced chronic arthropathy in a child. Clinical Pediatrics 1993;32:305-7. 67 McClain K, Estrov Z, Chen H, Mahoney DH, Jr. Chronic neutropenia of childhood: frequent association with parvovirus infection and correlations with bone marrow culture studies [see comments]. British Journal of Haematology 1993;85:57-62. 68 Hanada T, Koike K, Hirano C, Takeya T, Suzuki T, Matsunaga Y et al. Childhood transient erythroblastopenia complicated by thrombocytopenia and neutropenia. European Journal of Haematology 1989;42:77-80. 69 Heegaard ED, Rosthoj S, Petersen BL, Nielsen S, Karup PF, Hornsleth A. Role of parvovirus B19 infection in childhood idiopathic thrombocytopenic purpura. Acta Paediatrica 1999;88:614-7. 70 Elsacker-Niele AM, Weiland HT, Kroes AC, Kappers-Klunne MC. Parvovirus B19 infection and idiopathic thrombocytopenic purpura. Annals of Hematology 1996;72:141-4. 71 Lefrere JJ,.Got D. Peripheral thrombocytopenia in human parvovirus infection [letter]. Journal of Clinical Pathology 1987;40:469. 72 Frank R, Glander HJ, Haustein UF. [Dermatologic symptoms of parvovirus B19 infections]. [German]. Hautarzt 1996;47:365-8. 73 Naides SJ, Karetnyi YV, Cooling LL, Mark RS, Langnas AN. Human parvovirus B19 infection and hepatitis [letter; comment]. Lancet 1996;347:1563-4. 74. Finkel TH, Torok TJ, Ferguson PJ, Durigon EL, Zaki SR, Leung DY et al. Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent? [see comments]. Lancet 1994;343:1255-8. 75. Gilbert GL. Parvovirus B19 infection and its significance in pregnancy. [Review] [16 refs]. Communicable Diseases Intelligence 2000;24 Suppl:69-71. 76. Bell LM, Naides SJ, Stoffman P, Hodinka RL, Plotkin SA. Human parvovirus B19 infection among hospital staff members after contact with infected patients [see comments]. New England Journal of Medicine 1989;321:485-91. Parvovirus and Anaemia - science citation index search 1 Biesma DH,.Nieuwenhuis HK. Life-threatening anaemia caused by B19 parvovirus infection in a non-immunocompromised patient. Netherlands Journal Of Medicine 1997;50:81-4. 157 2 Brown KE. Haematological consequences of parvovirus B19 infection. Best Practice & Research Clinical Haematology 2000;13:245-59. 3 Harrison J,.Jones CE. Human Parvovirus B19 infection in health-care workers. Occupational Medicine-Oxford 1995;45:93-6. 4 Heegaard ED, Hasle H, Clausen N, Hornsleth A, Kerndrup GB. Parvovirus B19 infection and Diamond-Blackfan anaemia. Acta Paediatrica 1996;85:299-302. 5 Pillay D, Patou G, Hurt S, Kibbler CC, Griffiths PD. Parvovirus-B19 outbreak in a childrens ward. Lancet 1992;339:107-9. MEASLES VIRUS Occupational relevance 1. Houck P, Scott-Johnson G, Krebs L. Measles immunity among community hospital employees. Infection Control & Hospital Epidemiology 1991;12:663-8. 2. Jackson LA, Stewart LK, Solomon SL, Boase J, Alexander ER, Heath JL et al. Risk of infection with hepatitis A, B or C, cytomegalovirus, varicella or measles among child care providers. Pediatric Infectious Disease Journal 1996;15:584-9. 3. Kim M, LaPointe J, Liu FJ. Epidemiology of measles immunity in a population of healthcare workers. Infection Control & Hospital Epidemiology 1992;13:399-402. 4. Steingart KR, Thomas AR, Dykewicz CA, Redd SC. Transmission of measles virus in healthcare settings during a communitywide outbreak. Infection Control & Hospital Epidemiology 1999;20:115-9. 5. Willy ME, Koziol DE, Fleisher T, Koo S, McFarland H, Schmitt J et al. Measles immunity in a population of healthcare workers [see comments]. Infection Control & Hospital Epidemiology 1994;15:12-7. 6. Wright LJ,.Carlquist JF. Measles immunity in employees of a multihospital healthcare provider [see comments]. Infection Control & Hospital Epidemiology 1994;15:811. MEASLES AND CROHN'S DISEASE Measles and Crohn's Disease – medline search 1. Wakefield AJ,.Montgomery SM. Measles virus as a risk for inflammatory bowel disease: an unusually tolerant approach [editorial; comment]. [Review] [30 refs]. American Journal of Gastroenterology 2000;95:1389-92. 2. Andus T,.Gross V. Etiology and pathophysiology of inflammatory bowel disease-environmental factors. [Review] [256 refs]. Hepato-Gastroenterology 2000;47:29-43. 3. Wakefield AJ, Montgomery SM, Pounder RE. Crohn's disease: the case for measles virus. [Review] [75 refs]. Italian Journal of Gastroenterology & Hepatology 1999;31:247-54. 158 4. Rhodes J,.Freedman AR. Measles, mycobacterium paratuberculosis and Crohn's disease. [Review] [8 refs]. Italian Journal of Gastroenterology & Hepatology 1999;31:255-7. 5. Lione A,.Scialli AR. Perinatal exposure to measles virus and the risk of inflammatory bowel disease. [Review] [55 refs]. Reproductive Toxicology 1997;11:647-52. 6. Koutroubakis I, Manousos ON, Meuwissen SG, Pena AS. Environmental risk factors in inflammatory bowel disease. [Review] [125 refs]. Hepato-Gastroenterology 1996;43:38193. 7. Pounder RE. Measles virus and Crohn's disease: research from the Royal Free Hospital in London. Journal of Gastroenterology 1995;30 Suppl 8:48-51. 8. Wakefield AJ, Ekbom A, Dhillon AP, Pittilo RM, Pounder RE. Crohn's disease: pathogenesis and persistent measles virus infection. [Review] [54 refs]. Gastroenterology 1995;108:911-6. 9. Pounder RE. The pathogenesis of Crohn's disease. [Review] [9 refs]. Journal of Gastroenterology 1994; 29 Suppl 7:11-5. 10. Smith MS,.Wakefield AJ. Viral association with Crohn's disease. [Review] [56 refs]. Annals of Medicine 1993;25:557-61. 11. Pardi DS, Tremaine WJ, Sandborn WJ, Loftus EV, Jr., Poland GA, Harmsen WS et al. Early measles virus infection is associated with the development of inflammatory bowel disease [see comments]. American Journal of Gastroenterology 2000;95:1480-5. 12. Thompson NP, Montgomery SM, Wadsworth ME, Pounder RE, Wakefield AJ. Early determinants of inflammatory bowel disease: use of two national longitudinal birth cohorts. European Journal of Gastroenterology & Hepatology 2000;12:25-30. 13. Pardi DS, Tremaine WJ, Sandborn WJ, Loftus EV, Jr., Poland GA, Melton LJ et al. Perinatal exposure to measles virus is not associated with the development of inflammatory bowel disease. Inflammatory Bowel Diseases 1999;5:104-6. 14. Nielsen LL, Nielsen NM, Melbye M, Sodermann M, Jacobsen M, Aaby P. Exposure to measles in utero and Crohn's disease: Danish register study [see comments]. BMJ 1998;316:196-7. 15. Ekbom A, Daszak P, Kraaz W, Wakefield AJ. Crohn's disease after in-utero measles virus exposure [see comments]. Lancet 1996;348:515-7. 16. Balzola FA, Khan K, Pera A, Bonino F, Pounder RE, Wakefield AJ. Measles IgM immunoreactivity in patients with inflammatory bowel disease [see comments]. Italian Journal of Gastroenterology & Hepatology 1998;30:378-82. 17. Balzola FA, Castellino F, Colombatto P, Manzini P, Astegiano M, Verme G et al. IgM antibody against measles virus in patients with inflammatory bowel disease: a marker of virus-related disease? [see comments]. European Journal of Gastroenterology & Hepatology 1997;9:661-3. 18. Fisher NC, Yee L, Nightingale P, McEwan R, Gibson JA. Measles virus serology in Crohn's disease. Gut 1997;41:66-9. 159 19. Folwaczny C, Loeschke K, Schnettler D, Jager G, Wiebecke B, Hoelscher M et al. Endothelial cell autoantibodies are a marker of disease susceptibility in inflammatory bowel disease but apparently not linked to persistent measles virus infection. Clinical Immunology 2000;95:197-202. 20. Wakefield AJ, Sim R, Akbar AN, Pounder RE, Dhillon AP. In situ immune responses in Crohn's disease: a comparison with acute and persistent measles virus infection. Journal of Medical Virology 1997;51:90-100. 21. Ekbom A, Wakefield AJ, Zack M, Adami HO. Perinatal measles infection and subsequent Crohn's disease [see comments]. Lancet 1994;344:508-10. 22. Altschuler EL. Mycophenolate mofetil, Crohn's disease, measles? [letter; comment]. American Journal of Gastroenterology 2000;95:550-1. 23. Afzal MA, Minor PD, Armitage E, Ghosh S. Measles virus and Crohn's disease [letter; comment]. Gut 1999;44:896-7. 24. ter M, V. Measles virus and Crohn's disease: view of a medical virologist [see comments]. Gut 1998;43:733-4. 25. Stokkers PC, van den BM, Rings E. Measles vaccination and inflammatory bowel disease. Journal of Pediatric Gastroenterology & Nutrition 1998;27:239-40. 26. WHO concludes that measles viruses are not associated with Crohn's disease. Communicable Disease Report 1978;CDR Weekly. 8:75. 27. Metcalf J. Is measles infection associated with Crohn's disease? [editorial; comment] [see comments]. BMJ 1998;316:166. 28. Ward B,.DeWals P. Association between measles infection and the occurrence of chronic inflammatory bowel disease. Canada Communicable Disease Report 1997;23:1-5. 29. Jones P, Fine P, Piracha S. Crohn's disease and measles [letter; comment]. Lancet 1997;349 :473. 30. Orteu CH, McGregor JM, Whittaker SJ, Balzola F, Wakefield AJ. Erythema elevatum diutinum and Crohn disease: a common pathogenic role for measles virus? [letter]. Archives of Dermatology 1996;132:1523-5. 31. Katz J, Mordechai F, Itchak M, Isaac A, Shemer J. Measles, Crohn's disease, and recurrent oral ulceration [letter]. Lancet 1996;348:1250-1. 32. Touze I, Dubucquoi S, Cortot A, Van Kruiningen HJ, Colombel JF. IgM-specific measles-virus antibody in families with a high frequency of Crohn's disease [letter]. Lancet 1995;346:967. 33. Jewell DP. Pathogenesis of Crohn's disease: the environment revisited [comment]. European Journal of Gastroenterology & Hepatology 1995;7:383-4. 34. Hermon-Taylor J, Ford J, Sumar N, Millar D, Doran T, Tizard M. Measles virus and Crohn's disease [letter]. Lancet 1995;345:922-3. 160 35 Wakefield AJ,.Pounder RE. Measles virus in Crohn's disease [letter; comment]. Lancet 1995;345:66 36. Iizuka M, Nakagomi O, Chiba M, Ueda S, Masamune O. Absence of measles virus in Crohn's disease [letter] [see comments]. Lancet 1995;345:199. 37. Monif GR,.Hood CI. Ileocolitis associated with measles (rubeola). American Journal of Diseases of Children 1970;120:245-7. Measles and Crohn's Disease - science citation index search 1 Daszak P, Purcell M, Lewin J, Dhillon AP, Pounder RE, Wakefield AJ. Detection and comparative analysis of persistent measles virus infection in Crohn's disease by immunogold electron microscopy. Journal Of Clinical Pathology 1997;50:299-304. 2 Haga Y, Funakoshi O, Kuroe K, Kanazawa K, Nakajima H, Saito H et al. Absence of measles viral genomic sequence in intestinal tissues from Crohn's disease by nested polymerase chain reaction. Gut 1996;38:211-5. 3 Karlinger K, Gyorke T, Mako E, Mester A, Tarjan Z. The epidemiology and the pathogenesis of inflammatory bowel disease. European Journal Of Radiology 2000;35:15467. 4 Miyamoto H, Tanaka T, Kitamoto N, Fukuda Y, Shimoyama T. Detection of immunoreactive antigen, with a monoclonal-antibody to measles-virus, in tissue from a patient with Crohn's-Disease. Journal Of Gastroenterology 1995;30:28-33. 5 Van Kruiningen HJ, Mayo DR, Vanopdenbosch E, Gower-Rousseau C, Cortot A, Colombel JF. Virus serology in familial Crohn disease. Scandinavian Journal Of Gastroenterology 2000;35:403-7. 6 Wakefield AJ, Pittilo RM, Sim R, Cosby SL, Stephenson JR, Dhillon AP et al. Evidence of persistent measles-virus infection in Crohn's- disease. Journal Of Medical Virology 1993;39:345-53. MEASLES AND MULTIPLE SCLEROSIS Measles and Multiple Sclerosis – medline search (using filters) 1. Collins RC, Espinoza LR, Plank CR, Ebers GC, Rosenberg RA, Zabriskie JB. A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. Clinical & Experimental Immunology 1978;33:1-11. 2. Paty DW, Furesz J, Boucher DW, Rand CG, Stiller CR. Measles antibodies as related to HL-A types in multiple sclerosis. Neurology 1976;26:651-5. 3. Bansil S, Troiano R, Dowling PC, Cook SD. Measles vaccination does not prevent multiple sclerosis. Neuroepidemiology 1990;9:248-54. 4. Svenningsson A, Runmarker B, Lycke J, Andersen O. Incidence of MS during two fifteen-year periods in the Gothenburg region of Sweden. Acta Neurologica Scandinavica 1990;82:161-8. 161 5. Kinnunen E, Valle M, Piirainen L, Kleemola M, Kantanen ML, Juntunen J et al. Viral antibodies in multiple sclerosis. A nationwide co-twin study. Archives of Neurology 1990;47:743-6. 6. Caputo D, Ferrante P, Zaffaroni M, Ghezzi A, Cazzullo CL. Longitudinal survey of T-lymphocytes and viral antibodies in MS patients. Italian Journal of Neurological Sciences 1987;Suppl 6:53-6. 7. Ilonen J, Reunanen M, Salmi A, Herva E. Lymphocyte blast transformation responses to mitogens and specific antigens in different clinical phases of multiple sclerosis: a follow-up study. Acta Neurologica Scandinavica 1983;68:1-12. 8. Arnadottir T, Reunanen M, Meurman O, Salmi A, Panelius M, Halonen P. Measles and rubella virus antibodies in patients with multiple sclerosis. A longitudinal study of serum and CSF specimens by radioimmunoassay. Archives of Neurology 1979;36:261-5. 9. Reunanen M, Ilonen J, Arnadottir T, Ahonen A, Salmi A. Mitogen and antigen stimulation of multiple sclerosis cerebrospinal fluid lymphocytes in vitro. Journal of the Neurological Sciences 1983;58:211-21. 10. Arnadottir T, Reunanen M, Salmi A. Intrathecal synthesis of virus antibodies in multiple sclerosis patients. Infection & Immunity 1982;38:399-407. 11. Ryberg B. Acute measles infection in a case of multiple sclerosis. Acta Neurologica Scandinavica 1979;59:221-4. 12. Reiber H, Ungefehr S, Jacobi C. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Multiple Sclerosis 1998;4:111-7. 13. Bachmann S,.Kesselring J. Multiple sclerosis and infectious childhood diseases. Neuroepidemiology 1998;17:154-60. 14. Visudtibhan A, Mehta PD, Kulczycki J, Coyle PK, Thormar H. Intrathecal production of measles-specific IgA in subacute sclerosing panencephalitis. Acta Neurologica Scandinavica 1997; 96:97-100. 15. Kurtzke JF, Hyllested K, Arbuckle JD, Bronnum-Hansen H, Wallin MT, Heltberg A et al. Multiple sclerosis in the Faroe Islands. 7. Results of a case control questionnaire with multiple controls. Acta Neurologica Scandinavica 1997;96:149-57. 16. Bansil S, Singhal BS, Ahuja GK, Riise T, Ladiwala U, Behari M et al. Multiple sclerosis in India: a case-control study of environmental exposures. Acta Neurologica Scandinavica 1997;95:90-5. 17. Brankin B, Osman M, Herlihy L, Hawkins SA, Cosby SL. Failure to detect measles virus RNA, by reverse transcription-polymerase chain reaction, in peripheral blood leucocytes of patients with multiple sclerosis. Multiple Sclerosis 1996;1:204-6. 18. Casetta I, Granieri E, Malagu S, Tola MR, Paolino E, Caniatti LM et al. Environmental risk factors and multiple sclerosis: a community-based, case-control study in the province of Ferrara, Italy. Neuroepidemiology 1994;13:120-8. 162 19. Gronning M, Riise T, Kvale G, Albrektsen G, Midgard R, Nyland H. Infections in childhood and adolescence in multiple sclerosis. A case-control study. Neuroepidemiology 1993;12:61-9. 20. Hopkins RS, Indian RW, Pinnow E, Conomy J. Multiple sclerosis in Galion, Ohio: prevalence and results of a case-control study. Neuroepidemiology 1991;10:192-9. 21. Ferrante P, Castellani P, Barbi M, Bergamini F. The Italian Cooperative Multiple Sclerosis case-control study: preliminary results on viral antibodies. Italian Journal of Neurological Sciences 1987;Suppl 6:45-50. 22. Cooperative Italian study on multiple sclerosis and risk factors: a case-control study. The Coordinating Center and the Neurological Centers of the Cooperative Group. Italian Journal of Neurological Sciences 1987;Suppl 6:17-20. 23. Casetta I,.Granieri E. Clinical infections and multiple sclerosis: contribution from analytical epidemiology. [Review] [46 refs]. Journal of Neurovirology 2000;6 Suppl 2:S147S151. 24. Talwar GP, Diwan M, Razvi F, Malhotra R. The impact of new technologies on vaccines. [Review] [75 refs]. National Medical Journal of India 1999;12:274-80. 25. Shoenfeld Y,.Aron-Maor A. Vaccination and autoimmunity-'vaccinosis': a dangerous liaison?. [Review] [97 refs]. Journal of Autoimmunity 2000;14:1-10. 26. Ohara Y. Multiple sclerosis and measles virus. [Review] [28 refs]. Japanese Journal of Infectious Diseases 1999;52:198-200. 27. Triulzi F,.Scotti G. Differential diagnosis of multiple sclerosis: contribution of magnetic resonance techniques. [Review] [37 refs]. Journal of Neurology, Neurosurgery & Psychiatry 1998;64 Suppl 1:S6-14. 28. Gilden DH, Devlin ME, Burgoon MP, Owens GP. The search for virus in multiple sclerosis brain. [Review] [59 refs]. Multiple Sclerosis 1996;2:179-83. 29. Summers BA,.Appel MJ. Aspects of canine distemper virus and measles virus encephalomyelitis. [Review] [66 refs]. Neuropathology & Applied Neurobiology 1994;20:525-34. 30. Dhib-Jalbut S,.Jacobson S. Cytotoxic T cells in paramyxovirus infection of humans. [Review] [35 refs]. Current Topics in Microbiology & Immunology 1994;189:109-21. 31. Andersson M, Alvarez-Cermeno J, Bernardi G, Cogato I, Fredman P, Frederiksen J et al. Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report. [Review] [50 refs]. Journal of Neurology, Neurosurgery & Psychiatry 1994;57:897-902. 32. Sarchielli P, Trequattrini A, Usai F, Murasecco D, Gallai V. Role of viruses in the etiopathogenesis of multiple sclerosis. [Review] [60 refs]. Acta Neurologica 1993;15:363-81. 33. Pitts OM. A reconsideration of the measles-adherent leukocyte phenomenon and multiple sclerosis. [Review] [25 refs]. Medical Hypotheses 1993;41:55-8. 34. Rice GP. Virus-induced demyelination in man: models for multiple sclerosis. Review] [46 refs]. Current Opinion in Neurology & Neurosurgery 1992;5:188-94. 163 35. Hafler DA,.Weiner HL. T cells in multiple sclerosis and inflammatory central nervous system diseases. [Review] [68 refs]. Immunological Reviews 1987;100:307-32. 36. Neetens A. The visual system in myelin disorders. A bird's eye overview. [Review] [167 refs]. Bulletin de la Societe Belge d Ophtalmologie 1983;208 Pt 1:1-39. 37. Rosenberg RN. Recombinant DNA and neurologic disease: the coming of a new age. [Review] [30 refs]. Neurology 1983;33:622-5. 38. Valbonesi M,.Garelli S. Plasma exchange in neurological diseases. A critical approach. [Review] [93 refs]. Vox Sanguinis 1983;44:65-80. 39. Wild TF. Measles virus and chronic infections. [Review] [20 refs]. Pathologie Biologie 1981;29:429-33. 40. Borecky L. Interactions between viral infection and immune mechanisms. [Review] [69 refs]. Comparative Immunology, Microbiology & Infectious Diseases 1980;3:381-90. 41. Lisak RP. Multiple sclerosis: evidence for immunopathogenesis. [Review] [111 refs]. Neurology 1980;30:99-105. 42. Paterson PY. Joseph E. Smadel Memorial Lecture: neuroimmunologic diseases of animals and humans. [Review] [66 refs]. Reviews of Infectious Diseases 1979;1:469-82. 43. Behbehani AM. Slow-virus diseases: a concise review. [Review] [20 refs]. Journal of the Kansas Medical Society 1979;80:600-4. 44. Dubois-Dalcq M. Pathology of measles virus infection of the nervous system: comparison with multiple sclerosis. [Review] [109 refs]. International Review of Experimental Pathology 1979;19:101-35. 45. Albrecht P. Immune control in experimental subacute sclerosing panencephalitis. [Review] [73 refs]. American Journal of Clinical Pathology 1978;70:175-84. 46. Viola MV, Scott C, Duffy PD. Persistent measles virus infection in vitro and in man. [Review] [47 refs]. Arthritis & Rheumatism 1978;21:S47-S51. 47. Johnson RT,.ter M, V. Slow infections of the nervous system. [Review] [100 refs]. Advances in Internal Medicine 1978;23:353-83. 48. Morgan EM,.Rapp F. Measles virus and its associated diseases. [Review] [407 refs]. Bacteriological Reviews 1977;41:636-66. 49. Becker LE. Slow infections of the central nervous system. [Review] [91 refs]. Canadian Journal of Neurological Sciences 1977;4:81-8. 50. Haire M. Significance of virus antibodies in multiple sclerosis. [Review] [48 refs]. British Medical Bulletin 1977;33:40-4 51. Fraser KB. Multiple sclerosis: a virus disease?. [Review] [80 refs]. British Medical Bulletin 1977;33:34-9. 52. Acheson ED. Epidemiology of multiple sclerosis. [Review] [53 refs]. British Medical Bulletin 1977;33:9-14. 164 53. Currie S. Immunological factors in neurological disorders. [Review] [115 refs]. Modern Trends in Neurology 1975;6:17-33. 54. Koestner A. Animal model of human disease: subacute sclerosing panencephalitis, multiple sclerosis; animal model: distemper-associated demyelinating encephalomyelitis. [Review] [15 refs]. American Journal of Pathology 1975;78:361-4. 55. Kraft AM,.Wessman HC. Pathology and etiology in multiple sclerosis: a review. [Review] [14 refs]. Physical Therapy 1974;54:716-20. 56. Marsh RF. Slow virus diseases of the central nervous system. [Review] [105 refs]. Advances in Veterinary Science & Comparative Medicine 1974;18:155-78. 57. Riekkinen PJ, Rinne UK, Arstila AU, Roytta M. Chemical pathology of multiple sclerosis. [Review] [93 refs]. Annals of Clinical Research 1973;5:345-55. 58. Weiner LP, Johnson RT, Herndon RM. Viral infections and demyelinating diseases. [Review] [95 refs]. New England Journal of Medicine 1973;288:1103-10. 59. Cathala F,.Brown P. The possible viral aetiology of disseminated sclerosis. [Review] [80 refs]. Journal of Clinical Pathology - Supplement (Royal College of Pathologists) 1972;6:141-51. 60. AdaMS JM. Demyelinating diseases and certain virus infections. [Review] [73 refs]. Pathobiology Annual 1972;2:183-205. 61. Tourtellotte WW. Cerebrospinal fluid immunoglobulins and the central nervous system as an immunological organ particularly in multiple sclerosis and subacute sclerosing panencephalitis. [Review] [146 refs]. Research Publications - Association for Research in Nervous & Mental Disease 1971;49:112-55. HEPATITIS B and D Occupational relevance 1. Acute hepatitis B virus infection in children and teachers, England and Wales 1985 90. CDR (London: England Weekly) 1991;1:75-6. 2. Almi P, Toscano L, Rubino M, Toti M, Galluzzi P. Epidemiology of hepatitis B virus infection in the staff of a psychiatric hospital. Minerva Medica 1989;80:1011-4. 3. Amerena V,.Andrew JH. Hepatitis B virus: the risk to Australian dentists and dental healthcare workers. Australian Dental Journal 1987;32:183-9. 4. Anderson RA,.Woodfield DG. Hepatitis B virus infections in laboratory staff. New Zealand Medical Journal 1982;95:69-71. 5. Arnedo A, Latorre MD, Rosario PM, Safont L, Guillen F, Aguinaga I. Hepatitis A, B and C in an occupational center for the mentally handicapped. Enfermedades Infecciosas y Microbiologia Clinica 1998;16:370-3. 6. Arvanitidou M, Constantinidis TC, Doutsos J, Mandraveli K, Katsouyannopoulos V. Occupational hepatitis B virus infection in sewage workers. Medicina del Lavoro 165 1998;89:437-44. Ref ID: 3443 8. Arvanitidou M, Constantinidis TC, Doutsos J, Katsouyannopoulos VC. Prevalence of hepatitis a virus infection among the employees of a sewage organization. Acta Microbiologica Hellenica 1998;43:38-43. Ref ID: 4362 9. Bandaranayake DR, Salmond CE, Tobias MI. Occupational risk of hepatitis B for police and custoMS personnel. American Journal of Epidemiology 1991;134:1447-53. Ref ID: 4279 10. Bottcher-Buhler E. Occupational-related hepatitis virus infections. Fortschritte der Medizin 1994;112:28+30. Ref ID: 2149 11. Boxall EH. Risks to surgeons and patients from HIV and hepatitis [18]. British Medical Journal 1993; 306:652-3. Ref ID: 1863 12. Capilouto EI, Weinstein MC, Hemenway D, Cotton D. What is the dentist's occupational risk of becoming infected with hepatitis B or the human immunodeficiency virus? American Journal of Public Health 1992;82:587-9. Ref ID: 4261 13. Chriske HW, Abdo R, Richrath R, Braumann S. Danger of hepatitis B infection in sewerage and sewage works staff. Arbeitsmedizin Sozialmedizin Praventivmedizin 1990;25:475-7. Ref ID: 3922 14. Chronister CL,.Gurwood AS. Literature review of hepatitis B: should eye care practitioners receive a hepatitis B vaccine? [see comments]. [Review] [31 refs]. Optometry & Vision Science 1992;69:898-903. Ref ID: 1284 15. Corrao G, Zotti C, Sciacovelli A. Hepatitis A and B virus infection in dustmen and sewer workers. Giornale Italiano di Medicina del Lavoro 1985;7. Ref ID: 1628 16. Cottone JA,.Puttaiah R. Hepatitis B virus infection. Current status in dentistry. [Review] [62 refs]. Dental Clinics of North America 1996;40:293-307. Ref ID: 1016 17. Craig CP, Gribble C, Suarez K. Risk of hepatitis B among phlebotomists. American Journal of Infection Control 1981;9. Ref ID: 3750 18. Gerlich WH,.ThoMSsen R. Outbreak of hepatitis B at a butcher's. Deutsche Medizinische Wochenschrift 1982;107. Ref ID: 3740 19. Lanphear BP. Transmission and control of bloodborne viral hepatitis in healthcare workers. [Review] [127 refs]. Occupational Medicine 1997;12:717-30. Ref ID: 121 166 20. Lodi G, Porter SR, Scully C. Hepatitis C virus infection: Review and implications for the dentist. [Review] [270 refs]. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontics 1998;86:8-22. Ref ID: 1122 21. Mevorach D, Eliakim R, Brezis M. Hepatitis B - An occupational risk for butchers? [9]. Annals of Internal Medicine 1992;116:428. Ref ID: 1924 22. Mevorach D, Brezis M, Yishai FB, Sadeh T, Shouval D, Eliakim R. Increased risk of exposure to hepatitis B infection among butchers sharing knives. American Journal of Medicine 1999;106:479-80. Ref ID: 4342 23. Mijch AM, Barnes R, Crowe SM. An outbreak of hepatitis B and D in butchers. Scandinavian Journal of Infectious Diseases 1987;19. Ref ID: 3692 24. Mills PR, Thorburn D, McCruden EAB. Occupationally acquired hepatitis C infection. Reviews in Medical Microbiology 2000;11:15-22. Ref ID: 2611 25. Porter S, Scully C, Samaranayake L. Viral hepatitis. Current concepts for dental practice. [Review] [182 refs]. Oral Surgery, Oral Medicine, Oral Pathology 1994;78:682-95. Ref ID: 191 26. Porter SR,.Lodi G. Hepatitis C virus (HCV)--an occupational risk to dentists?. [Review] [21 refs]. British Dental Journal 1996;180:473-4. Ref ID: 1159 27. Shaoliang S, Luyuan S, Yuanjian W, Zhanzhao L, Cuanzheng Z, Yingping W et al. A seroepidemiologic study of hepatitis B virus infection among barbers in Huangshi City, Hubei, China. Microbiology & Immunology 1988;32:229-33. Ref ID: 3908 28. She SL, Shi LY, Wu YJ, Li ZZ, Zheng CZ, Wu YP et al. A seroepidemiologic study of hepatitis B virus infection among barbers in Huangshi City, Hubei, China. Microbiology & Immunology 1988;32:229-33. Ref ID: 1446 29. Shields JW. Clustered hepatitis B or human immunodeficiency virus transmission in office settings. Lymphology 1995;28:141-6. Ref ID: 1191 30. Siebert DJ, Lindschau PB, Burrell CJ. Lack of evidence for significant hepatitis B transmission in Australian Rules footballers. Medical Journal of Australia 1995;162:312-3. Ref ID: 2881 31. Springbett RJ, Cartwright KA, Watson BE, Morris R, Cantle A. Hepatitis B markers in Gloucestershire firemen. Occupational Medicine (Oxford) 1994;44:9-11. Ref ID: 1264 167 32. Wada Y, Kamiyama S, Koizumi A. Negligible risk of horizontal transmission of hepatitis B virus among mechanics and salespersons in the automobile industry [letter]. Industrial Health 1991;29:161-5. Ref ID: 1396 33. Wilcox CW, Mayhew RB, Lagree JD, Tiffany RL. Incidence of hepatitis B exposure among USAF dental laboratory technicians. American Journal of Dentistry 1990;3:236-8. Ref ID: 1387 34. WilliaMS BG,.Pruitt B. Natural and induced immunity to hepatitis B virus among the staff of a pediatric oncology center. American Journal of Infection Control 1984;12:261-5. Ref ID: 4927 35. Woodruff BA, Moyer LA, O'Rourke KM, Margolis HS. Blood exposure and the risk of hepatitis B virus infection in firefighters. Journal of Occupational Medicine 1993;35:1048- 54. Ref ID: 4206 HEPATITIS C Occupational relevance 1. Arnedo A, Latorre MD, Rosario PM, Safont L, Guillen F, Aguinaga I. Hepatitis A, B and C in an occupational center for the mentally handicapped. Enfermedades Infecciosas y Microbiologia Clinica 1998;16:370-3. Ref ID: 3098 2. Bottcher-Buhler E. Occupational-related hepatitis virus infections. Fortschritte der Medizin 1994;112:28+30. Ref ID: 2149 3. Boxall EH. Risks to surgeons and patients from HIV and hepatitis [18]. British Medical Journal 1993; 306:652-3. Ref ID: 1863 4. Lanphear BP. Transmission and control of bloodborne viral hepatitis in healthcare workers. [Review] [127 refs]. Occupational Medicine 1997;12:717-30. Ref ID: 121 5. Lodi G, Porter SR, Scully C. Hepatitis C virus infection: Review and implications for the dentist. [Review] [270 refs]. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontics 1998;86:8-22. Ref ID: 1122 6. . Mills PR, Thorburn D, McCruden EAB. Occupationally acquired hepatitis C infection. Reviews in Medical Microbiology 2000;11:15-22. Ref ID: 2611 7. Porter S, Scully C, Samaranayake L. Viral hepatitis. Current concepts for dental practice. [Review] [182 refs]. Oral Surgery, Oral Medicine, Oral Pathology 1994;78:682-95. Ref ID: 191 168 8. Porter SR,.Lodi G. Hepatitis C virus (HCV)--an occupational risk to dentists?. [Review] [21 refs]. British Dental Journal 1996;180:473-4. Ref ID: 1159 9. Shaoliang S, Luyuan S, Yuanjian W, Zhanzhao L, Cuanzheng Z, Yingping W et al. A seroepidemiologic study of hepatitis B virus infection among barbers in Huangshi City, Hubei, China. Microbiology & Immunology 1988;32:229-33. Ref ID: 3908 HUMAN T-CELL LYMPHOTROPIC VIRUS Occupational Relevance 1. HTLV missionaries and parasites [letter]. Lancet 1984;2:927-8. 2. Avolio G, Cimino T, Malavenda P. Risk of HIV (HTLV-III/LAV) infection in hospital staff. Medicolegal aspects. Minerva Medicolegale 1987;107:203-6. 3. Erfle V, Hehlmann R, Mellert W, Kruger G, Seifried E, Heimpel H et al. Prevalence of antibodies to HTLV-III in AIDS risk groups in West Germany. Cancer Research 1985;45:4627s-9s. 4. Jones P,.Hamilton P. HTLV-III antibodies in haematology staff [letter]. Lancet 1985;1 :217. 5. Lewandowski C, Ognjan A, Rivers E, Huitsing H, Pohlod D, Lee H et al. Healthcare worker exposure to HIV-1 and HTLV I-II in critically ill, resuscitated emergency department patients. Annals of Emergency Medicine 1992;21:1353-9. 6. Murphy EL, Wilks R, Hanchard B, Cranston B, Figueroa JP, Gibbs WN et al. A case control study of risk factors for seropositivity to human T-lymphotropic virus type I (HTLVI) in Jamaica. International Journal of Epidemiology 1996; 25:1083-9. 7. Murphy EL, Wilks R, Morgan OS, Hanchard B, Cranston B, Figueroa JP et al. Health effects of human T-lymphotropic virus type I (HTLV-I) in a Jamaican cohort. International Journal of Epidemiology 1996;25:1090-7. 8. Norrgren H, Andersson S, Naucler A, Dias F, Johansson I, Biberfeld G. HIV-1, HIV 2, HTLV-I/II and Treponema pallidum infections: Incidence, prevalence, and HIV-2associated mortality in an occupational cohort in Guinea-Bissau. JAIDS: Journal of Acquired Immune Deficiency Syndromes 1995;9:422-8. 9. Reitz JM, Hall L, Robert-Guroff M, Lautenberger J, Hahn BM, Shaw GM et al. Viral variability and serum antibody response in a laboratory worker infected with HIV type 1 (HTLV type IIIB). AIDS Research & Human Retroviruses 1994;10:1143-55. 10. Singer DR,.Almdal TP. Potential route of transmission of HTLV-III [letter]. Journal of Infection 1986;12:86-7. 11. Stricof RL,.Morse DL. HTLV-III/LAV seroconversion following intramuscular needlestick injury. New England Journal of Medicine 1986;314. 169 a deep 12. Stuver SO, Tachibana N, Okayama A, Romano F, Yokota T, Mueller N. Determinants of HTLV-1 seroprevalence in Miyazaki Prefecture, Japan: a cross-sectional study. Journal of Acquired Immune Deficiency Syndromes 1992;5:12-8. 13. Weiss SH, Saxinger WC, Rechtman D, Grieco MH, Nadler J, Holman S et al. HTLVIII infection among healthcare workers. Association with needle-stick injuries. JAMA 1985;254:2089-93. HUMAN IMMUNODEFICIENCY VIRUSES Occupational relevance 1. Astbury C,.Baxter P. Doctors' HIV risk difficult to quantify [30]. British Medical Journal 1993;307:205. 2. Avidan MS, Jones N, Pozniak AL. The implications of HIV for the anaesthetist and the intensivist. Anaesthesia 2000;55:344-54. 3. Bailey M. Occupational HIV infection risk. Lancet 1990;335:1104-5. 4. Boxall EH. Risks to surgeons and patients from HIV and hepatitis [18]. British Medical Journal 1993;306:652-3. 5. Castro KG, Dooley SW, Curran JW. Transmission of HIV-associated tuberculosis to health-care workers [23]. Lancet 1992;340:1043-4. 6. Coggin JJ. Preventing HIV transmission to healthcare workers (III). CMAJ 1991;144:408-9. 7. Fry DE. HIV and other viruses in surgery: a continued occupational risk. [Review] [40 refs]. Advances in Cardiac Surgery 1993;4:237-53. 8. Lin EY,.Brunicardi FC. HIV infection and surgeons. [Review] [47 refs]. World Journal of Surgery 1994;18:753-7 9. Puro V, Ranchino M, Profili F. Occupational exposures to blood and risk of HIV transmission in a general hospital (1986-88). European Journal of Epidemiology 1990;6:6770. 10. Robert LM,.Bell DM. HIV transmission in the health-care setting: Risks to health care workers and patients. Infectious Disease Clinics of North America 1994;8:319-29. * The total number of occupational papers was too numerous to list here. A selection of reviews is given above. HUMAN PAPILLOMAVIRUSES Occupational relevance 1. AbraMSon AL, DiLorenzo TP, Steinberg BM. Is papillomavirus detectable in the plume of laser-treated laryngeal papilloma? Archives of Otolaryngology -- Head & Neck Surgery 1990;116:604-7. 170 2. Al-Ghamdi AA, Sanders CM, Keefe M, Coggon D, Maitland, NJ. Human papillomavirus DNA and TP53 mutations in lung cancers from butchers. British Journal of Cancer 1995;72:293-7. 3. al Ghamdi AA, Sanders CM, Keefe M, Coggon D, Maitland NJ. Human papillomavirus DNA and TP53 mutations in lung cancers from butchers. British Journal of Cancer 1995;72:293-7. 4. Andre P, Orth G, Evenou P, Guillaume JC, Avril MF. Risk of papillomavirus infection in carbon dioxide laser treatment of genital lesions. Journal of the American Academy of Dermatology 1990;22:131-2. 5. Cothran MM,.White JE. Update on human papillomavirus. [Review] [57 refs]. Journal of the American Academy of Nurse Practitioners 1995;7:583-9. 6. Deitmer T,.Wiener C. Is there an occupational etiology of inverted papilloma of the nose and sinuses? Acta Oto-Laryngologica 1996;116:762-5. 7. Ferenczy A, Bergeron C, Richart RM. Human papillomavirus DNA in CO2 laser generated plume of smoke and its consequences to the surgeon. Obstetrics & Gynecology 1990;75:114-8. 8. Genner J, Scheutz F, Ebbesen P, Melbye M. Antibody to human papilloma virus in Danish dentists. Scandinavian Journal of Dental Research 1988;96:118-20. 9. Gloster HM, Jr.,.Roenigk RK. Risk of acquiring human papillomavirus from the plume produced by the carbon dioxide laser in the treatment of warts. Journal of the American Academy of Dermatology 1995;32:436-41. 10. Guran S,.Pak I. Cumulation of TP53 mutations and p16INK4A/p15INK4B homozygous deletions in human papilloma virus type 16 positive scrotal cancer. Cancer Genetics & Cytogenetics 1999;109:108-13. 11. Hippelainen M, Syrjanen S, Koskela H, Pulkkinen J, Saarikoski S, Syrjanen K. Prevalence and risk factors of genital human papillomavirus (HPV) infections in healthy males: a study on Finnish conscripts. Sexually Transmitted Diseases 1993;20:321-8. 12. Melchers W, De Mare S, Kuitert E, Galama J, Walboomers J, Van den B et al. Human papillomavirus and cutaneous warts in meat handlers. Journal of Clinical Microbiology 1993;31:2547-9. 13. Orth G, Jablonska S, Favre M. Identification of papillomaviruses in butchers' warts. Journal of Investigative Dermatology 1981;76. COXIELLA BURNETII (Q FEVER) Occupational relevance 1. Botros BA, Soliman AK, Salib AW, Olson J, Hibbs RG, WilliaMS JC et al. Coxiella burnetii antibody prevalences among human populations in north-east Africa determined by enzyme immunoassay. Journal of Tropical Medicine & Hygiene 1995;98:173-8. 171 2. Fishbein DB,.Raoult D. A cluster of Coxiella burnetii infections associated with exposure to vaccinated goats and their unpasteurized dairy products. American Journal of Tropical Medicine & Hygiene 1992;47:35-40. 3. Htwe KK, Yoshida T, Hayashi S, Miyake T, Amano K, Morita C et al. Prevalence of antibodies to Coxiella burnetii in Japan. Journal of Clinical Microbiology 1993;31:722-3. 4. Literak I. Prevalence of antibodies to Coxiella burnetii in blood donors in the Czech Republic. Central European Journal of Public Health 1994;2:52-4. 5. Perez-Trallero E, Cilla G, Montes M, Saenz-Dominguez JR, Alcorta M. Prevalence of Coxiella burnetii infection among slaughterhouse workers in northern Spain [letter]. European Journal of Clinical Microbiology & Infectious Diseases 1995;14:71-3. 6. Riemann HP, Brant PC, Behymer DE, Franti CE. Toxoplasma gondii and Coxiella burneti antibodies among Brazilian slaughterhouse employees. American Journal of Epidemiology 1975;102:386-93. 7. Ross C,.Morrow PS. Q fever: an issue in occupational health & safety? An overview of the methods of control and the effects of Coxiella burnetii on the human host. [Review] [7 efs]. Journal of the Royal Society of Health 1994;114:151-2. 8. Sadecky E. Infection of cattle and livestock handlers with Coxiella burnetti and Chlamydiae in the farm of Bernolakovo (West Slovakia). Journal of Hygiene, Epidemiology, Microbiology & Immunology 1981;25:52-9. 9. Thibon M, Villiers V, Souque P, Dautry-Varsat A, Duquesnel R, Ojcius DM. High incidence of Coxiella burnetii markers in a rural population in France. European Journal of Epidemiology 1996;12:509-13. 10. Blidaru I, Lamba N, Petrescu C. A Q fever episode in a municipal slaughter house. Bacteriologia, Virusologia, Parazitologia, Epidemiologia 1982;27. 11. Casolin A. Q fever in New South Wales Department of Agriculture workers. Journal Of Occupational And Environmental Medicine 1999;41:273-8. 12. Davies TR, Edwards Y, Morgan A, Caul EO. Prevalence of Q fever in a rural practice. Journal of Public Health Medicine 1997;19:324-7. 13. Edlinger EA. Q fever in France. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene - Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology 1987;267:26-9. 14. Garner MG, Longbottom HM, Cannon RM, Plant AJ. A review of Q fever in Australia 1991-1994 [see comments]. Australian & New Zealand Journal of Public Health 1997;21:722-30. 15. Levesque B, De Serres G, Higgins R, D'Halewyn MA, Artsob H, Grondin J et al. Seroepidemiologic study of three zoonoses (leptospirosis, Q fever, and tularemia) among trappers in Quebec, Canada. Clinical & Diagnostic Laboratory Immunology 1995;2:496-8. 16. Marmion BP, OrMSbee RA, Kyrkou M, Wright J, Worswick D, Cameron S et al. Vaccine prophylaxis of abattoir-associated Q fever. Lancet 1984;2:1411-4. 172 17. Martin RJ, Schnurrenberger PR, Ferris DH, Hanger PN, Morrissey RA. Decreasing prevalence of Q fever in Illinois. Public Health Reports 1982;97:170-4. 18. McKelvie P. Q fever in a Queensland meatworks. Medical Journal of Australia 1980;1. 19 Richardus JH, Donkers A, Dumas AM, Schaap GJ, Akkermans JP, Huisman J et al. Q fever in the Netherlands: a sero-epidemiological survey among human population groups from 1968 to 1983. Epidemiology & Infection 1987;98:211-9. 20. Ruppanner R, Brooks D, Franti CE, Behymer DE, Morrish D, Spinelli J. Q fever hazards from sheep and goats used in research. Archives of Environmental Health 1982;37:103-10. 21. Shapiro RA, Siskind V, Schofield FD, Stallman N, Worswick DA, Marmion et al. A randomized, controlled, double-blind, cross-over, clinical trial of Q fever vaccine in selected Queensland abattoirs. Epidemiology & Infection 1990;104:267-73. 22. Simor AE, Brunton JL, Salit IE, Vellend H, Ford-Jones L, Spence LP. Q fever: haard from sheep used in research. CMAJ 1984;130:1013-6. 23. Thomas DR, Treweek L, Salmon RL, Kench SM, Coleman TJ, Meadows D et al. The risk of acquiring Q fever on farms: a seroepidemiological study. Occupational & Environmental Medicine 1995;52:644-7. 24. Winner SJ, Eglin RP, Moore VIM, Mayon-White RT. An outbreak of Q fever affecting postal workers in Oxfordshire. Journal of Infection 1987;14. Coxiella and neuropsychiatric disorders and endocarditis Coxiella and Neuropsychiatric Disorders and Endocarditis – medline search 1. Serbezov VS, Kazar J, Novkirishki V, Gatcheva N, Kovacova E, Voynova V. Q fever in Bulgaria and Slovakia. [Review] [40 refs]. Emerging Infectious Diseases 1999;5:388-94. 2. Maurin M,.Raoult D. Q fever. [Review] [426 refs]. Clinical Microbiology Reviews 1999;12:518-53. 3. Berbari EF, Cockerill FR, III, Steckelberg JM. Infective endocarditis due to unusual or fastidious microorganisms. [Review] [78 refs]. Mayo Clinic Proceedings 1997;72:532-42. 4. Siegman-Igra Y, Kaufman O, Keysary A, Rzotkiewicz S, Shalit I. Q fever endocarditis in Israel and a worldwide review. [Review] [110 refs]. Scandinavian Journal of Infectious Diseases 1997;29:41-9. 5. Stein A,.Raoult D. Q fever endocarditis [see comments]. [Review] [58 refs]. European Heart Journal 1995;16 Suppl B:19-23. 6. Baca OG. Pathogenesis of rickettsial infections emphasis on Q fever. [Review] [59 refs]. European Journal of Epidemiology 1991;7:222-8. 7. Raoult D. Host factors in the severity of Q fever. [Review] [26 refs]. Annals of the New York Academy of Sciences 1990;590:33-8. 173 8. Braimbridge MV,.Eykyn SJ. Prosthetic valve endocarditis. [Review] [35 refs]. Journal of Antimicrobial Chemotherapy 1987;20 Suppl A:173-80. 9. Young SE. Aetiology and epidemiology of infective endocarditis in England and Wales. [Review] [16 refs]. Journal of Antimicrobial Chemotherapy 1987;20 Suppl A:7-15. 10. Sawyer LA, Fishbein DB, McDade JE. Q fever: current concepts. [Review] [133 refs]. Reviews of Infectious Diseases 1987;9:935-46. Ref ID: 107 11. Lovey PY, Morabia A, Bleed D, Peter O, Dupuis G, Petite J. Long term vascular complications of Coxiella burnetii infection in Switzerland: cohort study [see comments]. BMJ 1999;319:284-6. 12. Raoult D, Tissot-Dupont H, Foucault C, Gouvernet J, Fournier PE, Bernit et al. Q fever 1985-1998. Clinical and epidemiologic features of 1,383 infections [see comments]. Medicine 2000;79:109-23. 13. Ayres JG, Flint N, Smith EG, Tunnicliffe WS, Fletcher TJ, Hammond K et al. Post infection fatigue syndrome following Q fever. QJM 1998;91:105-23. 14. Ghigo E, Capo C, Amirayan N, Raoult D, Mege J. The 75-kD tumour necrosis factor (TNF) receptor is specifically up-regulated in monocytes during Q fever endocarditis. Clinical & Experimental Immunology 2000;121:295-301. 15. Penttila IA, Harris RJ, Storm P, Haynes D, Worswick DA, Marmion BP. Cytokine dysregulation in the post-Q-fever fatigue syndrome [see comments]. QJM 1998;91:549-60. 16. Dellacasagrande J, Ghigo E, Capo C, Raoult D, Mege JL. Coxiella burnetii survives in monocytes from patients with Q fever endocarditis: involvement of tumor necrosis factor. Infection & Immunity 2000;68:160-4. 17. To H, Hotta A, Yamaguchi T, Fukushi H, Hirai K. Antigenic characteristic of the lipopolysaccharides of Coxiella burnetii isolates. Journal of Veterinary Medical Science 1998;60:267-70. 18. Sabatier F, Dignat-George F, Mege JL, Brunet C, Raoult D, Sampol J. CD4+ T-cell lymphopenia in Q fever endocarditis. Clinical & Diagnostic Laboratory Immunology 1997;4:89-92. 19. Capo C, Zugun F, Stein A, Tardei G, Lepidi H, Raoult D et al. Upregulation of tumor necrosis factor alpha and interleukin-1 beta in Q fever endocarditis. Infection & Immunity 1996;64:1638-42. 20. Thiele D,.WilleMS H. Is plasmid based differentiation of Coxiella burnetii in 'acute' and 'chronic' isolates still valid? European Journal of Epidemiology 1994;10:427-34. 21. McCaul TF, Dare AJ, Gannon JP, Galbraith AJ. In vivo endogenous spore formation by Coxiella burnetii in Q fever endocarditis. Journal of Clinical Pathology 1994;47:978-81. 22. Stein A,.Raoult D. Lack of pathotype specific gene in human Coxiella burnetii isolates. Microbial Pathogenesis 1993;15:177-85. 174 23. Duval X, Debord T, Fournier B, Darie H, Lemoing V, Roue R. Q fever with cutaneous and encephalitic involvement [letter]. Lancet 1993;341:1094-5. 24. Izzo AA, Marmion BP, Hackstadt T. Analysis of the cells involved in the lymphoproliferative response to Coxiella burnetii antigens. Clinical & Experimental Immunology 1991;85:98-108. 25. Savinelli EA,.Mallavia LP. Comparison of Coxiella burnetii plasmids to homologous chromosomal sequences present in a plasmidless endocarditis-causing isolate. Annals of the New York Academy of Sciences 1990;590:523-33. 26. Miragliotta G, Fumarola D, Brezina R. The ability of mononuclear cells to coagulate blood in response to Coxiella burnetii. Journal of Medical Microbiology 1989;29:9-12. 27. Koster FT, WilliaMS JC, Goodwin JS. Cellular immunity in Q fever: specific lymphocyte unresponsiveness in Q fever endocarditis. Journal of Infectious Diseases 1985;152:1283-9. 28. Samuel JE, Frazier ME, Mallavia LP. Correlation of plasmid type and disease caused by Coxiella burnetii. Infection & Immunity 1985;49:775-9. 29. Koster FT, WilliaMS JC, Goodwin JS. Cellular immunity in Q fever: modulation of responsiveness by a suppressor T cell-monocyte circuit. Journal of Immunology 1985;135:1067-72. 30. Graham JV, Baden L, Tsiodras S, Karchmer AW. Q fever endocarditis associated with extensive serological cross-reactivity. Clinical Infectious Diseases 2000;30:609-10. 31. Camacho MT, Outschoorn I, Echevarria C, Kovacova E, Yebra M, Mate I et al. Distribution of IgA subclass response to Coxiella burnetii in patients with acute and chronic Q fever. Clinical Immunology & Immunopathology 1998;88:80-3. 32. Soriano F, Camacho MT, Ponte C, Gomez P. Serological differentiation between acute (late control) and endocarditis Q fever. Journal of Clinical Pathology 1993;46:411-4. 33. Marrie TJ, Cunning J, Durnford P. Reactivation of Q fever following cardiac surgery. European Journal of Clinical Microbiology & Infectious Diseases 1992;11:833-6. 34. Raoult D, Levy PY, Harle JR, Etienne J, Massip P, Goldstein F et al. Chronic Q fever: diagnosis and follow-up. Annals of the New York Academy of Sciences 1990;590:51-60. 35. Renvoize EB, Awad IO, Hambling MH. A sero-epidemiological study of conventional infectious agents in Alzheimer's disease. Age & Ageing 1987;16:311-4. 36. Dupuis G, Peter O, Luthy R, Nicolet J, Peacock M, Burgdorfer W. Serological diagnosis of Q fever endocarditis. European Heart Journal 1986;7:1062-6. 37. Coyle PV, Thompson J, Adgey AA, Rutter DA, Fay A, McNeill TA et al. Changes in circulating immune complex concentrations and antibody titres during treatment of Q fever endocarditis. Journal of Clinical Pathology 1985;38:743-6. 38. Peacock MG, Philip RN, WilliaMS JC, Faulkner RS. Serological evaluation of Q fever in humans: enhanced phase I titers of immunoglobulins G and A are diagnostic for Q fever endocarditis. Infection & Immunity 1983;41:1089-98. 175 39. Yuasa Y, Yoshiie K, Takasaki T, Yoshida H, Oda H. Retrospective survey of chronic Q fever in Japan by using PCR to detect Coxiella burnetii DNA in paraffin-embedded clinical samples. Journal of Clinical Microbiology 1996;34:824-7. 40. Odeh M,.Oliven A. Temporal arteritis associated with acute Q fever. A case report. Angiology 1994;45:1053-7. 41. Peter O, Dupuis G, Bee D, Luthy R, Nicolet J, Burgdorfer W. Enzyme-linked immunosorbent assay for diagnosis of chronic Q fever. Journal of Clinical Microbiology 1988;26:1978-82. 42. Edlinger E. Immunofluorescence serology. A tool for prognosis of Q-fever. Diagnostic Microbiology & Infectious Disease 1985;3:343-51. 43. Boyle B,.Hone R. Q fever endocarditis revisited. Irish Journal of Medical Science 1999;168:53-4. 44. Hoen B, Selton-Suty C, Lacassin F, Etienne J, Briancon S, Leport C et al. Infective endocarditis in patients with negative blood cultures: analysis of 88 cases from a one-year nationwide survey in France. Clinical Infectious Diseases 1995;20:501-6. 45. Brouqui P, Dupont HT, Drancourt M, Berland Y, Etienne J, Leport C et al. Chronic Q fever. Ninety-two cases from France, including 27 cases without endocarditis. Archives of Internal Medicine 1993;153:642-8. 46. Hwang YM, Lee MC, Suh DC, Lee WY. Coxiella (Q fever)-associated myelopathy. Neurology 1993;43:338-42. 47. Drancourt M, Raoult D, Xeridat B, Milandre L, Nesri M, Dano P. Q fever meningoencephalitis in five patients. European Journal of Epidemiology 1991;7:134-8. 48. Connolly JH, Coyle PV, Adgey AA, O'Neill HJ, Simpson DM. Clinical Q fever in Northern Ireland 1962-1989. Ulster Medical Journal 1990;59:137-44. 49 Reilly S, Northwood JL, Caul EO. Q fever in Plymouth, 1972-88. A review with particular reference to neurological manifestations. Epidemiology & Infection 1990;105:391408. 50. Fergusson RJ, Shaw TR, Kitchin AH, Matthews MB, Inglis JM, Peutherer JF. Subclinical chronic Q fever. Quarterly Journal of Medicine 1985;57:669-76. 51. Haldane EV, Marrie TJ, Faulkner RS, Lee SH, Cooper JH, MacPherson DD et al. Endocarditis due to Q fever in Nova Scotia: experience with five patients in 1981-1982. Journal of Infectious Diseases 1983;148:978-85. 52. Ellis ME, Smith CC, Moffat MA. Chronic or fatal Q-fever infection: a review of 16 patients seen in North-East Scotland (1967-80). Quarterly Journal of Medicine 1983;52:5466. 53. Tobin MJ, Cahill N, Gearty G, Maurer B, Blake S, Daly K et al. Q fever endocarditis. American Journal of Medicine 1982;72:396-400. 54. Varma MP, Adgey AA, Connolly JH. Chronic Q fever endocarditis. British Heart Journal 1980;43:695-9. 176 55. Turck WP, Howitt G, Turnberg LA, Fox H, Longson M, Matthews MB et al. Chronic Q fever. Quarterly Journal of Medicine 1976;45:193-217. 56. Wilson HG, Neilson GH, Galea EG, Stafford G, O'Brien MF. Q fever endocarditis in Queensland. Circulation 1976;53:680-4. 57. Ghassemi M, Agger WA, Vanscoy RE, Howe GB. Chronic sternal wound infection and endocarditis with Coxiella burnetii. Clinical Infectious Diseases 1999;28:1249-51. 58. Julius P, Kutscha A, Ullmer E, Matthys H, Hamm H. A case of atypical pneumonia presenting with severe headache and disorientation. Diagnosis: Q fever (Coxiella burnetti). Respiration 1999;66:283-6. 59. Granel B, Genty I, Serratrice J, Rey J, Disdier P, Raoult D et al. Livedo reticularis revealing a latent infective endocarditis due to Coxiella burnetti. Journal of the American Academy of Dermatology 1999;41:842-4. 60. Lupoglazoff JM, Brouqui P, Magnier S, Hvass U, Casasoprana A. Q fever tricuspid valve endocarditis. Archives of Disease in Childhood 1997;77:448-9. 61. al Hajjar S, Hussain Qadri SM, al Sabban E, Jager C. Coxiella burnetii endocarditis in a child. Pediatric Infectious Disease Journal 1997;16:911-3. 62. Dalmau D, Castane J, Alvarez E, Ortega L, Garau J. A case of Q fever endocarditis treated medically: 9 years of follow-up [letter]. Infection 1997;25:131-2. 63. Vacher-Coponat H, Dussol B, Raoult D, Casanova P, Berland Y. Proliferative glomerulonephritis revealing chronic Q fever. American Journal of Nephrology 1996;16:15961. 64. Isalska BJ, Curry A, Stanbridge TN, Tweddle D, Caul EO. Electron microscopy and serological features of a patient with Q fever prosthetic valve endocarditis. Journal of Clinical Pathology 1996;49:679-87. 65. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-1996. An 18-year-old man with severe headache, pleocytosis, and ataxia [clinical conference]. New England Journal of Medicine 1996;335:1829-34. 66. Bental T, Fejgin M, Keysary A, Rzotkiewicz S, Oron C, Nachum R et al. Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. Clinical Infectious Diseases 1995;21:1318-21. 67. Tolosa-Vilella C, Rodriguez-Jornet A, Font-Rocabanyera J, Andreu N, X. Mesangioproliferative glomerulonephritis and antibodies to phospholipids in a patient with acute Q fever: case report. Clinical Infectious Diseases 1995;21:196-8. 68. Muhlemann K, Matter L, Meyer B, Schopfer K. Isolation of Coxiella burnetii from heart valves of patients treated for Q fever endocarditis. Journal of Clinical Microbiology 1995;33:428-31. 69. Bernard E, Carles M, Laffont C, Durant J, Dellamonica P. Guillain-Barre syndrome associated with acute Q fever. European Journal of Clinical Microbiology & Infectious Diseases 1994;13:658-9. 177 70. Odeh M,.Oliven A. Temporal arteritis associated with acute Q fever. A case report. Angiology 1994;45:1053-7 71. Lohuis PJ, Ligtenberg PC, Diepersloot RJ, de Graaf M. Q-fever in a patient with a ventriculo-peritoneal drain. Case report and short review of the literature. [Review] [29 refs]. Netherlands Journal of Medicine 1994;44:60-4. 72. Sempere AP, Elizaga J, Duarte J, Moreno J, Cepeda C, Calvo T et al. Q fever mimicking herpetic encephalitis. Neurology 1993;43:2713-4. 73. Schattner A, Kushnir M, Zhornicky T, Fenakel G. Lymphocytic meningitis as the sole manifestation of Q fever. Postgraduate Medical Journal 1993;69:636-7. 74. Ferrante MA,.Dolan MJ. Q fever meningoencephalitis in a soldier returning from the Persian Gulf War. [Review] [47 refs]. Clinical Infectious Diseases 1993;16:489-96. 75. Guerrero M, Gutierrez J, Carnero C, Gonzalez-Maldonado R, Maroto C. Acute meningoencephalitis as the sole manifestation of Q fever. European Journal of Clinical Microbiology & Infectious Diseases 1993;12:35-7. 76. Duval X, Debord T, Fournier B, Darie H, Lemoing V, Roue R. Q fever with cutaneous and encephalitic involvement [letter]. Lancet 1993;341:1094-5. 77. Meis JF, Weemaes CR, Horrevorts AM, Aerdts SJ, Westenend PJ, Galama JM. Rapidly fatal Q-fever pneumonia in a patient with chronic granulomatous disease. Infection 1992;20:287-9. 78. Wilson AP, Handler CE, Ridgway GL, Treharne J, Walker JM, Mangham DC. Coxiella burneti endocarditis in a patient with positive chlamydial serology. Journal of Infection 1992;25 Suppl 1:111-8. 79. Bonetti B, Monaco S, Ferrari S, Tezzon F, Rizzuto N. Demyelinating polyradiculoneuritis following Coxiella burnetti infection (Q fever). Italian Journal of Neurological Sciences 1991;12:415-7. 80. Diaz OA, Maeztu C, Munoz JA, Reigadas R, Rodriguez T, Valdes M. Miller Fisher syndrome associated with Q fever. Journal of Neurology, Neurosurgery & Psychiatry 1990;53:615-6. 81. Cameron DA, Freedman AR, Wansbrough-Jones MH. Q fever encephalitis. Journal of Infection 1990;20:159-62. 82. Shaked Y,.Samra Y. Q fever meningoencephalitis associated with bilateral abducens nerve paralysis, bilateral optic neuritis and abnormal cerebrospinal fluid findings. Infection 1989;17:394-5. 83. Khavkin T. Coxiella burnetii infection in prosthetic devices [letter; comment]. Reviews of Infectious Diseases11:835-Oct. 84. Lev BI, Shachar A, Segev S, Weiss P, Rubinstein E. Quiescent Q fever endocarditis exacerbated by cardiac surgery and corticosteroid therapy. Archives of Internal Medicine 1988;148:1531-2. 178 85. Noseda A, Liesnard C, Goffin Y, Thys JP. Q fever endocarditis: relapse five years after successful valve replacement for a first unrecognized episode. Journal of Cardiovascular Surgery 1988;29:360-3. 86. Fernandez-Guerrero ML, Muelas JM, Aguado JM, Renedo G, Fraile J, Soriano et al. Q fever endocarditis on porcine bioprosthetic valves. Clinicopathologic features and microbiologic findings in three patients treated with doxycycline, cotrimoxazole, and valve replacement. Annals of Internal Medicine 1988;108:209-13. 87. van Iseghem P, Van de WF, Desmyter J, De Geest H. An unexpected Q fever endocarditis. Report of a case. Acta Cardiologica 1987;42:475-81. Ref ID: 103 88. Westlake P, Price LM, Russell M, Kelly JK. The pathology of Q fever hepatitis. A case diagnosed by liver biopsy. Journal of Clinical Gastroenterology 1987;9:357-63. Ref ID: 108 89. Raoult D, Piquet P, Gallais H, de Micco C, Drancourt M, Casanova P. Coxiella burnetii infection of a vascular prosthesis [letter]. New England Journal of Medicine 1986;315:1358-9. Ref ID: 110 90. Brooks RG, Licitra CM, Peacock MG. Encephalitis caused by Coxiella burnetii. Annals of Neurology 1986;20:91-3. Ref ID: 111 91. Pierce MA, Saag MS, Dismukes WE, Cobbs CG. Q fever endocarditis. American Journal of the Medical Sciences 1986;292:104-6. Ref ID: 112 92. Laufer D, Lew PD, Oberhansli I, Cox JN, Longson M. Chronic Q fever endocarditis with massive splenomegaly in childhood. Journal of Pediatrics 1986;108:535-9. Ref ID: 113 93. Berkovitch M, Aladjem M, Beer S, Cohar K. A fatal case of Q fever hepatitis in a child. Helvetica Paediatrica Acta 1985;40:87-91. Ref ID: 115 94 Saginur R, Silver SS, Bonin R, Carlier M, Orizaga M. Q-fever endocarditis. CMAJ 1985;133:1228-30. Ref ID: 118 95 Marrie TJ. Pneumonia and meningo-encephalitis due to Coxiella burnetii. Journal of Infection 1985;11:59-61. Ref ID: 120 96. Schuil J, Richardus JH, Baarsma GS, Schaap GJ. Q fever as a possible cause of bilateral optic neuritis. British Journal of Ophthalmology 1985;69:580-3. Ref ID: 123 97. Moles K, Scott ME, O'Kane H, Connolly JH. Unsuspected Q fever endocarditis--a case report. Ulster Medical Journal 1984;53:74-5. Ref ID: 126 179 98. Jones RW,.Pitcher DW. Q fever endocarditis in a 6-year-old child. Archives of Disease in Childhood 1980;55:312-5. Ref ID: 136 99. Hillary IB, Dooley S, Meenan PN. Q fever in the Republic of Ireland: an update. Irish Journal of Medical Science 1980;149:59-62. Ref ID: 137 100. Kimbrough RC, III, OrMSbee RA, Peacock M, Rogers WR, Bennetts RW, Raaf J et al. Q fever endocarditis in the United States. Annals of Internal Medicine 1979; 91:400-2. Ref ID: 138 101. Willey RF, Matthews MB, Peutherer JF, Marmion BP. Chronic cryptic Q-fever infection of the heart. Lancet 1979;2:270-2. Ref ID: 139 102. Uff JS,.Evans DJ. Mesangio-capillary glomerulonephritis associated with Q-fever endocarditis. Histopathology 1977;1:463-72. Ref ID: 141 Coxiella and Neuropsychiatric Disorders and Endocarditis - science citation index search 1 Ben Ameur Y, Haouala H, Fehri W, Rahal N, Mhenni H, Guediche M. Coxiella burnetti endocarditis: about one case. Annales De Cardiologie Et D Angeiologie 1997; 46:671-3. 2 Fournier PE, Casalta JP, Piquet P, Tournigand P, Branchereau A, Raoult D. Coxiella burnetii infection of aneurysMS or vascular grafts: Report of seven cases and review. Clinical Infectious Diseases 1998;26:116-21. 3 Jourdain P, Pousset F, Ganty J, Komajda M, Thomas D. Silent Q fever endocarditis: A case report. Archives Des Maladies Du Coeur Et Des Vaisseaux 1999;92:915-7. 4 Maillet JM, BenHamda K, Fouchard J. Coxiella burnetti prosthetic valve endocarditis: A case report. Archives Des Maladies Du Coeur Et Des Vaisseaux 1996; 89: 95-7. 5 Sotto A, Lamaury I, Jonquet O, Bertrand A, Janbon F. Infection of an abdominal aortic-aneurysm by Coxiella-burnetti 8 years after acute Q-fever. Semaine Des Hopitaux 1994;70:211-3. CHLAMYDIA PNEUMONIAE Occupational relevance 1. Bourke SJ, Carrington D, Frew CE, McSharry CP, Boyd G. A comparison of the seroepidemiology of chlamydial infection in pigeon fanciers and farmers in the U.K. Journal of Infection 1992;25:91-8. Ref ID: 1766 180 2 Ni AP, Lin GY, Yang L, He HY, Huang CW, Liu ZJ et al. A seroepidemiologic study of Chlamydia pneumoniae, Chlamydia trachomatis and Chlamydia psittaci in different populations on the mainland of China. Scandinavian Journal of Infectious Diseases 1996;28:553-7. Ref ID: 131 3. Normann E, Gnarpe J, Gnarpe H, Wettergren B. Chlamydia pneumoniae in children attending day-care centers in Gavle, Sweden. Pediatric Infectious Disease Journal 1998;17:474-8. Ref ID: 2409 CHLAMYDIA AND ASTHMA (USING FILTERS) Chlamydia and Asthma – medline search (using filters) 1. Hahn DL. Chlamydia pneumoniae, asthma, and COPD: what is the evidence?. [Review] [167 refs]. Annals of Allergy, Asthma, & Immunology 291;83:271-88. 2. Daian CM, Wolff AH, Bielory L. The role of atypical organisms in asthma. [Review] [20 refs]. Allergy & Asthma Proceedings 2000;21:107-11. Ref ID: 32 3. Black PN, Scicchitano R, Jenkins CR, Blasi F, Allegra L, Wlodarczyk J et al. Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma. European Respiratory Journal 2000;15:254-9. Ref ID: 33 4. Hahn DL. Treatment of Chlamydia pneumoniae infection in adult asthma: a before after trial [see comments]. Journal of Family Practice 1995;41:345-51. Ref ID: 34 5. Ebell MH. C pneumoniae in adult asthma [comment]. Journal of Family Practice 1995;41:405-6. Ref ID: 35 6. Vachon F,.Kernbaum S. Acute bronchopulmonary infections: treatment with i.v. spiramycin. Chemioterapia 1987;6:282-5. Ref ID: 36 7. Mills GD, Lindeman JA, Fawcett JP, Herbison GP, Sears MR. Chlamydia pneumoniae serological status is not associated with asthma in children or young adults. International Journal of Epidemiology 2000;29:280-4. Ref ID: 2 8. Petitjean J, Vincent F, Fretigny M, Vabret A, Poveda JD, Brun J et al. Comparison of two serological methods and a polymerase chain reaction-enzyme immunoassay for the diagnosis of acute respiratory infections with Chlamydia pneumoniae in adults. Journal of Medical Microbiology 1998;47:615-21. Ref ID: 3 9. Cook PJ, Davies P, Tunnicliffe W, Ayres JG, Honeybourne D, Wise R. Chlamydia pneumoniae and asthma [see comments]. Thorax 1998;53:254-9. Ref ID: 4 181 10. Teichtahl H, Buckmaster N, Pertnikovs E. The incidence of respiratory tract infection in adults requiring hospitalization for asthma. Chest 1997;112:591-6. Ref ID: 5 11. Emre U, Roblin PM, Gelling M, Dumornay W, Rao M, Hammerschlag MR et al. The association of Chlamydia pneumoniae infection and reactive airway disease in children [see comments]. Archives of Pediatrics & Adolescent Medicine 1994;148:727-32. Ref ID: 6 12. Hahn DL, Dodge RW, Golubjatnikov R. Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma [see comments]. JAMA 1991;266:225-30. Ref ID: 7 13. Montan PG, Ekstrom K, Hedlin G, Hage-HaMSten M, Hjern A, Herrmann B. Vernal keratoconjunctivitis in a Stockholm ophthalmic centre--epidemiological, functional, and immunologic investigations. Acta Ophthalmologica Scandinavica 1999;77:559-63. Ref ID: 8 14. Hahn DL. Treatment of Chlamydia pneumoniae infection in adult asthma: a before after trial [see comments]. Journal of Family Practice 1995;41:345-51. Ref ID: 9 15. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults [see comments]. BMJ 1993;307:982-6. Ref ID: 10 16. Hahn DL. Treatment of Chlamydia pneumoniae infection in adult asthma: a before after trial [see comments]. Journal of Family Practice 1995;41:345-51. Ref ID: 11 17. Mills GD, Lindeman JA, Fawcett JP, Herbison GP, Sears MR. Chlamydia pneumoniae serological status is not associated with asthma in children or young adults. International Journal of Epidemiology 2000;29:280-4. Ref ID: 12 18. Routes JM, Nelson HS, Noda JA, Simon FT. Lack of correlation between Chlamydia pneumoniae antibody titers and adult-onset asthma. Journal of Allergy & Clinical Immunology 2000;105:391-2. Ref ID: 13 19. Montan PG, Ekstrom K, Hedlin G, Hage-HaMSten M, Hjern A, Herrmann B. Vernal keratoconjunctivitis in a Stockholm ophthalmic centre--epidemiological, functional, and immunologic investigations. Acta Ophthalmologica Scandinavica 1999;77:559-63. Ref ID: 14 20. Hahn DL. Chlamydia pneumoniae, asthma, and COPD: what is the evidence?. [Review] [167 refs]. Annals of Allergy, Asthma, & Immunology 291;83:271-88. Ref ID: 15 21. Ursi D, Ieven M, Van Bever HP, Goossens H. Construction of an internal control for the detection of Chlamydia pneumoniae by PCR. Molecular & Cellular Probes 1998; 12: 235-8. Ref ID: 16 182 22. Hahn DL, Anttila T, Saikku P. Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma. Epidemiology & Infection 1996;117:513-7. Ref ID: 17 23. Emre U, Roblin PM, Gelling M, Dumornay W, Rao M, Hammerschlag MR et al. The association of Chlamydia pneumoniae infection and reactive airway disease in children [see comments]. Archives of Pediatrics & Adolescent Medicine 1994;148:727-32. Ref ID: 18 24. Hahn DL, Dodge RW, Golubjatnikov R. Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma [see comments]. JAMA 1991;266:225-30. Ref ID: 19 25. Daian CM, Wolff AH, Bielory L. The role of atypical organisms in asthma. [Review] [20 refs]. Allergy & Asthma Proceedings 2000;21:107-11. Ref ID: 20 26. Douglass JA,.O'Hehir RE. What determines asthma phenotype? Respiratory infections and asthma. [Review] [48 refs]. American Journal of Respiratory & Critical Care Medicine 2000;161:S211-S214. Ref ID: 21 27. Nelson HS. Allergen and irritant control: importance and implementation. [Review] [40 refs]. Clinical Cornerstone 1998;1:57-68. Ref ID: 22 28. Cook PJ. Antimicrobial therapy for Chlamydia pneumoniae: its potential role in atherosclerosis and asthma. [Review] [51 refs]. Journal of Antimicrobial Chemotherapy 1999;44:145-8. Ref ID: 23 29. Johnston SL. The role of viral and atypical bacterial pathogens in asthma pathogenesis. [Review] [13 refs]. Pediatric Pulmonology - Supplement 1999;18:141-3. Ref ID: 24 30. Hahn DL. Chlamydia pneumoniae, asthma, and COPD: what is the evidence?. [Review] [167 refs]. Annals of Allergy, Asthma, & Immunology 291;83:271-88. Ref ID: 25 31. Hueston WJ,.Mainous AG, III. Acute bronchitis [see comments]. [Review] [39 refs]. American Family Physician 1281;57:1270-6. Ref ID: 26 32. Johnston SL. Influence of viral and bacterial respiratory infections on exacerbations and symptom severity in childhood asthma. [Review] [10 refs]. Pediatric Pulmonology - Supplement 1997;16:88-9. Ref ID: 27 33. Laurila AL, Von Hertzen L, Saikku P. Chlamydia pneumoniae and chronic lung diseases. [Review] [46 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1997;104:34-6. Ref ID: 28 183 34. Cosentini R,.Blasi F. New pathogens for respiratory infections. [Review] [69 refs]. Current Opinion in Pulmonary Medicine 1996;2:174-80. Ref ID: 29 35. Peeling RW,.Brunham RC. Chlamydiae as pathogens: new species and new issues. [Review] [78 refs]. Emerging Infectious Diseases 1996;2:307-19. Ref ID: 30 36. Grayston JT. Infections caused by Chlamydia pneumoniae strain TWAR [see comments]. [Review] [2 refs]. Clinical Infectious Diseases 1992;15:757-61. Ref ID: 31 CHLAMYDIA PNEUMONIAE AND HEART DISEASE Chlamydia and heart disease – medline search (using filters) 1. Famularo G, Trinchieri V, Santini G, De Simone C. Infections, atherosclerosis, and coronary heart disease. [Review] [115 refs]. Annali Italiani di Medicina Interna 2000;15:144- 55. Ref ID: 1 2. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000;20:52-63. Ref ID: 2 3. Carlisle SS,.Nahata MC. Chlamydia pneumoniae and coronary heart disease. [Review] [74 refs]. Annals of Pharmacotherapy 1999;33:615-22. Ref ID: 3 4. Wong YK, Gallagher PJ, Ward ME. Chlamydia pneumoniae and atherosclerosis. [Review] [88 refs]. Heart 1999;81:232-8. Ref ID: 4 5. Gibbs RG, Carey N, Davies AH. Chlamydia pneumoniae and vascular disease. [Review] [87 refs]. British Journal of Surgery 1998;85:1191-7. Ref ID: 5 6. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta analysis [see comments]. BMJ 2000;321:208-13. Ref ID: 6 7. Fong IW. Emerging relations between infectious diseases and coronary artery disease and atherosclerosis. [Review] [95 refs]. CMAJ 2000;163:49-56. Ref ID: 7 8. Jackson LA. Description and status of the azithromycin and coronary events study (ACES). Journal of Infectious Diseases 2000;181 Suppl 3:S579-S581. Ref ID: 8 184 9. Dunne MW. Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. Journal of Infectious Diseases 2000;181 Suppl 3:S572-S578. Ref ID: 9 10. Anderson JL,.Muhlestein JB. The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). Journal of Infectious Diseases 2000;181 Suppl 3:S569-S571. Ref ID: 10 11. Gurfinkel E. Inflammation, infection, or both in atherosclerosis: the ROXIS trial in perspective. [Review] [13 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S566-S568. Ref ID: 11 12. Meier CR. Antibiotics in the prevention and treatment of coronary heart disease. [Review] [61 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S558-S562. Ref ID: 12 13. Schmidt C, Hulthe J, Wikstrand J, Gnarpe H, Gnarpe J, Agewall S et al. Chlamydia pneumoniae seropositivity is associated with carotid artery intima-media thickness. Stroke 2000;31:1526-31. Ref ID: 13 14. Romeo F, Martuscelli E, Chirieolo G, Cerabino LM, Ericson K, Saldeen TG et al. Seropositivity against Chlamydia pneumoniae in patients with coronary atherosclerosis. Clinical Cardiology 2000;23:327-30. Ref ID: 14 15. Carlsson J, Miketic S, Brom J, Ross R, Bachmann H, Tebbe U. Prior cytomegalovirus, Chlamydia pneumoniae or Helicobacter pylori infection and the risk of restenosis after percutaneous transluminal coronary angioplasty. International Journal of Cardiology 2000;73:165-71. Ref ID: 15 16. Danesh J, Wong Y, Ward M, Muir J. Risk factors for coronary heart disease and persistent infection with Chlamydia pneumoniae or cytomegalovirus: a population-based study. Journal of Cardiovascular Risk 1999;6:387-90. Ref ID: 16 17. Anderson JL, Muhlestein JB, Carlquist J, Allen A, Trehan S, Nielson C et al. Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection: The Azithromycin in Coronary Artery Disease: Elimination of Myocardial Infection with Chlamydia (ACADEMIC) study [see comments]. Circulation 1999;99:1540-7. Ref ID: 17 18. Lindholt JS, Vammen S, Lind I, Fasting H, Henneberg EW. The progression of lower limb atherosclerosis is associated with IgA antibodies against Chlamydia pneumoniae [published erratum appears in Eur J Vasc Endovasc Surg 2000 Mar;19(3):332]. European Journal of Vascular & Endovascular Surgery 1999;18:527-9. Ref ID: 18 185 19. Kahler J, Koster R, Braser JH, Schafer P, Terres W, Hamm CW et al. [Role of Chlamydia pneumoniae in the pathogenesis of coronary disease]. [Review] [86 refs] [German]. Zeitschrift fur Kardiologie 1999;88:885-95. Ref ID: 19 20. Roivainen M, Viik-Kajander M, Palosuo T, Toivanen P, Leinonen M, Saikku et al. Infections, inflammation, and the risk of coronary heart disease. Circulation 2000;101:252-7. Ref ID: 20 21. Dunne M. WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics. [Review] [5 refs]. American Heart Journal 1999;138:S542- S544. Ref ID: 21 22. Gupta S. Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. [Review] [13 refs]. American Heart Journal 1999;138:S539-S541. Ref ID: 22 23. Melissano G, Blasi F, Esposito G, Tarsia P, Dordoni L, Arosio C et al. Chlamydia pneumoniae eradication from carotid plaques. Results of an open, randomised treatment study. European Journal of Vascular & Endovascular Surgery 1999;18:355-9. Ref ID: 23 24. Coles KA, Plant AJ, Riley TV, Smith DW, McQuillan BM, Thompson PL. Lack of association between seropositivity to Chlamydia pneumoniae and carotid atherosclerosis. American Journal of Cardiology 1999;84:825-8. Ref ID: 24 25. Movahed MR. Infection with Chlamydia pneumoniae and atherosclerosis: a review. [Review] [49 refs]. Journal - South Carolina Medical Association 1999;95:303-8. Ref ID: 25 26. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999;81:245-7. Ref ID: 26 27. Maraha B, Scheffer GJ, Kluytmans JA, Den Heijer M, Graafsma S, Peeters et al. [Chlamydia pneumonia and atherosclerosis (letter; comment)]. [Dutch]. Nederlands Tijdschrift voor Geneeskunde 1999;143:762-3. Ref ID: 27 28. Lindholt JS, Fasting H, Henneberg EW, Ostergaard L. A review of Chlamydia pneumoniae and atherosclerosis. [Review] [57 refs]. European Journal of Vascular & Endovascular Surgery 1999;17:283-9. Ref ID: 28 29. Gurfinkel E, Bozovich G, Beck E, Testa E, Livellara B, Mautner B. Treatment with the antibiotic roxithromycin in patients with acute non-Q-wave coronary syndromes. The final report of the ROXIS Study [see comments]. European Heart Journal 1999;20:121-7. Ref ID: 29 186 30. Fagerberg B, Gnarpe J, Gnarpe H, Agewall S, Wikstrand J. Chlamydia pneumoniae but not cytomegalovirus antibodies are associated with future risk of stroke and cardiovascular disease: a prospective study in middle-aged to elderly men with treated hypertension. Stroke 1999;30:299-305. Ref ID: 30 31. Jackson LA, Stewart DK, Wang SP, Cooke DB, Cantrell T, Grayston JT. Safety and effect on anti-Chlamydia pneumoniae antibody titres of a 1 month course of daily azithromycin in adults with coronary artery disease. Journal of Antimicrobial Chemotherapy 1999;44:411-4. Ref ID: 31 32. Kolmos HJ,.Gluud CN. [Infections and cardiovascular disease]. [Review] [39 refs] [Danish]. Ugeskrift for Laeger 1999;161:5161-4. Ref ID: 32 33. Laurila AL, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Chlamydia pneumoniae antibodies associated with altered serum lipid profile. International Journal of Circumpolar Health 1998;57 Suppl 1:329-32. Ref ID: 33 34. Maass M, Bartels C, Kruger S, Krause E, Engel PM, Dalhoff K. Endovascular presence of Chlamydia pneumoniae DNA is a generalized phenomenon in atherosclerotic vascular disease. Atherosclerosis 1998;140 Suppl 1:S25-S30. Ref ID: 34 35. Gurfinkel E. Is there something more behind atherosclerotic plaque inflammation? [editorial]. European Heart Journal 1998;19:677-8. Ref ID: 35 36. Gupta S,.Camm AJ. Is there an infective aetiology to atherosclerosis?. [Review] [57 refs]. Drugs & Aging 1998;13:1-7. Ref ID: 36 37. Yamashita K, Ouchi K, Shirai M, Gondo T, Nakazawa T, Ito H. Distribution of Chlamydia pneumoniae infection in the athersclerotic carotid artery. Stroke 1998;29:773-8. Ref ID: 37 38. Sinisalo J, Mattila K, Nieminen MS, Valtonen V, Syrjala M, Sundberg S et al. The effect of prolonged doxycycline therapy on Chlamydia pneumoniae serological markers, coronary heart disease risk factors and forearm basal nitric oxide production. Journal of Antimicrobial Chemotherapy 1998;41:85-92. Ref ID: 38 39. Muhlestein JB, Anderson JL, Hammond EH, Zhao L, Trehan S, Schwobe EP et al. Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. Circulation 1998;97:633-6. Ref ID: 39 40. Gurfinkel E, Bozovich G, Daroca A, Beck E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group [see comments]. Lancet 1997;350:404-7. Ref ID: 40 187 41. Mendall MA, Patel P, Ballam L, Strachan D, Northfield TC. C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study [see comments]. BMJ 1996;312:1061-5. Ref ID: 41 42. Patel P, Mendall MA, Carrington D, Strachan DP, Leatham E, Molineaux N et al. Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors [see comments] [published erratum appears in BMJ 1995 Oct 14;311(7011):985]. BMJ 1995;311:711-4. Ref ID: 42 43. Saikku P, Leinonen M, Tenkanen L, Linnanmaki E, Ekman MR, Manninen V et al. Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study [see comments]. Annals of Internal Medicine 1992; 116:273-8. Ref ID: 43 44. Mahony JB, Chong S, Coombes BK, Smieja M, Petrich A. Analytical sensitivity, reproducibility of results, and clinical performance of five PCR assays for detecting Chlamydia pneumoniae DNA in peripheral blood mononuclear cells. Journal of Clinical Microbiology 2000;38:2622-7. Ref ID: 84 45. Carlsson J, Miketic S, Brom J, Ross R, Bachmann H, Tebbe U. Prior cytomegalovirus, Chlamydia pneumoniae or Helicobacter pylori infection and the risk of restenosis after percutaneous transluminal coronary angioplasty. International Journal of Cardiology 2000;73:165-71. Ref ID: 85 46. Glader CA, Boman J, Saikku P, Stenlund H, Weinehall L, Hallmanns G et al. The proatherogenic properties of lipoprotein(a) may be enhanced through the formation of circulating immune complexes containing Chlamydia pneumoniae-specific IgG antibodies [see comments]. European Heart Journal 2000;21:639-46. Ref ID: 86 47. Bartels C, Maass M, Bein G, Malisius R, Brill N, Bechtel JF et al. Detection of Chlamydia pneumoniae but not cytomegalovirus in occluded saphenous vein coronary artery bypass grafts. Circulation 1999;99:879-82. Ref ID: 87 48. Biasucci LM, Liuzzo G, Grillo RL, Caligiuri G, Rebuzzi AG, Buffon A et al. Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability. Circulation 1999;99:855-60. Ref ID: 88 49. Danesh J, Wong Y, Ward M, Muir J. Risk factors for coronary heart disease and persistent infection with Chlamydia pneumoniae or cytomegalovirus: a population-based study. Journal of Cardiovascular Risk 1999;6:387-90. Ref ID: 89 50. Grau A,.Buggle F. [Infection, atherosclerosis and acute ischemic cerebrovascular disease]. [Review] [38 refs] [Spanish]. Revista de Neurologia 1999;29:847-51. Ref ID: 90 188 51. Ammann P, Marschall S, Kraus M, Schmid L, Angehrn W, Krapf R et al. Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest 2000;117:333-8. Ref ID: 91 52. Roivainen M, Viik-Kajander M, Palosuo T, Toivanen P, Leinonen M, Saikku et al. Infections, inflammation, and the risk of coronary heart disease. Circulation 2000;101:252-7. Ref ID: 92 53. Wong Y, Thomas M, Tsang V, Gallagher PJ, Ward ME. The prevalence of Chlamydia pneumoniae in atherosclerotic and nonatherosclerotic blood vessels of patients attending for redo and first time coronary artery bypass graft surgery [see comments]. Journal of the American College of Cardiology 1999;33:152-6. Ref ID: 93 54. Jantos CA, Nesseler A, Waas W, Baumgartner W, Tillmanns H, Haberbosch W. Low prevalence of Chlamydia pneumoniae in atherectomy specimens from patients with coronary heart disease [see comments]. Clinical Infectious Diseases 1999;28:988-92. Ref ID: 94 55. Nadrchal R, Makristathis A, Apfalter P, Rotter M, Trubel W, Huk I et al. Detection of Chlamydia pneumoniae DNA in atheromatous tissues by polymerase chain reaction. Wiener Klinische Wochenschrift 1999;111:153-6. Ref ID: 95 56. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999;81:245-7. Ref ID: 96 57. Gurfinkel E, Bozovich G, Beck E, Testa E, Livellara B, Mautner B. Treatment with the antibiotic roxithromycin in patients with acute non-Q-wave coronary syndromes. The final report of the ROXIS Study [see comments]. European Heart Journal 1999;20:121-7. Ref ID: 97 58. Altman R, Rouvier J, Scazziota A, Absi RS, Gonzalez C. Lack of association between prior infection with Chlamydia pneumoniae and acute or chronic coronary artery disease. Clinical Cardiology 1999;22:85-90. Ref ID: 98 59. Maass M, Bartels C, Kruger S, Krause E, Engel PM, Dalhoff K. Endovascular presence of Chlamydia pneumoniae DNA is a generalized phenomenon in atherosclerotic vascular disease. Atherosclerosis 1998;140 Suppl 1:S25-S30. Ref ID: 99 60. Ouchi K, Fujii B, Kanamoto Y, Karita M, Shirai M, Nakazawa T. Chlamydia pneumoniae in coronary and iliac arteries of Japanese patients with atherosclerotic cardiovascular diseases. Journal of Medical Microbiology 1998;47:907-13. Ref ID: 100 61. Boman J, Soderberg S, Forsberg J, Birgander LS, Allard A, Persson K et al. High prevalence of Chlamydia pneumoniae DNA in peripheral blood mononuclear cells in patients with cardiovascular disease and in middle-aged blood donors. Journal of Infectious Diseases 1998;178:274-7. Ref ID: 101 189 62. Lindholt JS, Ostergard L, Henneberg EW, Fasting H, Andersen P. Failure to demonstrate Chlamydia pneumoniae in symptomatic abdominal aortic aneurysMS by a nested polymerase chain reaction (PCR). European Journal of Vascular & Endovascular Surgery 1998;15:161-4. Ref ID: 102 63. Ossewaarde JM, Feskens EJ, De Vries A, Vallinga CE, Kromhout D. Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not. Epidemiology & Infection 1998;120:93-9. Ref ID: 103 64. Maass M, Bartels C, Engel PM, Mamat U, Sievers HH. Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease. Journal of the American College of Cardiology 1998;31:827-32. Ref ID: 104 65. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Chronic Chlamydia pneumoniae infection is associated with a serum lipid profile known to be a risk factor for atherosclerosis. Arteriosclerosis, Thrombosis & Vascular Biology 1997;17:2910-3. Ref ID: 105 66. Maass M, Krause E, Engel PM, Kruger S. Endovascular presence of Chlamydia pneumoniae in patients with hemodynamically effective carotid artery stenosis. Angiology 1997;48:699-706. Ref ID: 106 67. Blasi F, Denti F, Erba M, Cosentini R, Raccanelli R, Rinaldi A et al. Detection of Chlamydia pneumoniae but not Helicobacter pylori in atherosclerotic plaques of aortic aneurysMS. Journal of Clinical Microbiology 1996;34:2766-9. Ref ID: 107 68. Sutter MC. Lessons for atherosclerosis research from tuberculosis and peptic ulcer [editorial]. CMAJ 1995;152:667-70. Ref ID: 108 69. Hahn DL,.Golubjatnikov R. Smoking is a potential confounder of the Chlamydia pneumoniae-coronary artery disease association. Arteriosclerosis & Thrombosis 1992;12:945- 7. Ref ID: 109 70. Choussat R, Montalescot G, Collet J, Jardel C, Ankri A, Fillet A et al. Effect of prior exposure to Chlamydia pneumoniae, Helicobacter pylori, or cytomegalovirus on the degree of inflammation and one-year prognosis of patients with unstable angina pectoris or non-Q-wave acute myocardial infarction. American Journal of Cardiology 2000;86:379-84. Ref ID: 44 71. Zhu J, Quyyumi AA, Norman JE, Csako G, Waclawiw MA, Shearer GM et al. Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels. American Journal of Cardiology 2000;85:140-6. Ref ID: 45 190 72. Famularo G, Trinchieri V, Santini G, De Simone C. Infections, atherosclerosis, and coronary heart disease. [Review] [115 refs]. Annali Italiani di Medicina Interna 2000;15:144- 55. Ref ID: 46 73. Mayr M, Kiechl S, Willeit J, Wick G, Xu Q. Infections, immunity, and atherosclerosis: associations of antibodies to Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus with immune reactions to heat-shock protein 60 and carotid or femoral atherosclerosis. Circulation 2000;102:833-9. Ref ID: 47 74. West R. Commentary: adjustment for potential confounders may have been taken too far [comment]. BMJ 2000;321:213. Ref ID: 48 75. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta analysis [see comments]. BMJ 2000;321:208-13. Ref ID: 49 76. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses [see comments]. BMJ 2000;321:199-204. Ref ID: 50 77. Siscovick DS, Schwartz SM, Caps M, Wang SP, Grayston JT. Chlamydia pneumoniae and atherosclerotic risk in populations: the role of seroepidemiology. [Review] [26 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S417-S420. Ref ID: 51 78. Saikku P. Epidemiologic association of Chlamydia pneumoniae and atherosclerosis: the initial serologic observation and more. [Review] [21 refs]. Journal of Infectious Diseases 2000; 181 Suppl 3:S411-S413. Ref ID: 52 79. Apfalter P, Loidl M, Nadrchal R, Makristathis A, Rotter M, Bergmann M et al. Isolation and continuous growth of Chlamydia pneumoniae from arterectomy specimens. European Journal of Clinical Microbiology & Infectious Diseases 2000;19:305-8. Ref ID: 53 80. Romeo F, Martuscelli E, Chirieolo G, Cerabino LM, Ericson K, Saldeen TG et al. Seropositivity against Chlamydia pneumoniae in patients with coronary atherosclerosis. Clinical Cardiology 2000;23:327-30. Ref ID: 54 81. Wick G. Atherosclerosis--an autoimmune disease due to an immune reaction against heat-shock protein 60. [Review] [23 refs]. Herz 2000;25:87-90. Ref ID: 55 82. Haberbosch W,.Jantos C. Chlamydia pneumoniae infection is not an independent risk factor for arterial disease. [Review] [33 refs]. Herz 2000;25:79-83. Ref ID: 56 191 83. Kaftan AH,.Kaftan O. Coronary artery disease and infection with chlamydia pneumonia. Japanese Heart Journal 2000;41:165-72. Ref ID: 57 84. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000; 20:52-63. Ref ID: 58 85. Fortini A, Corti G, Cappelletti C. [Chlamydia pneumoniae and atherosclerosis]. [Review] [95 refs] [Italian]. Annali Italiani di Medicina Interna 1999;14:253-63. Ref ID: 59 86. Gupta S. Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. [Review] [13 refs]. American Heart Journal 1999;138:S539-S541. Ref ID: 60 87. Saikku P. Epidemiology of Chlamydia pneumoniae in atherosclerosis. [Review] [38 refs]. American Heart Journal 1999;138:S500-S503. Ref ID: 61 88. Danesh J. Coronary heart disease, Helicobacter pylori, dental disease, Chlamydia pneumoniae, and cytomegalovirus: meta-analyses of prospective studies. American Heart Journal 1999; 138:S434-S437. Ref ID: 62 89. Melissano G, Blasi F, Esposito G, Tarsia P, Dordoni L, Arosio C et al. Chlamydia pneumoniae eradication from carotid plaques. Results of an open, randomised treatment study. European Journal of Vascular & Endovascular Surgery 1999;18:355-9. Ref ID: 63 90. Nieto FJ, Folsom AR, Sorlie PD, Grayston JT, Wang SP, Chambless LE. Chlamydia pneumoniae infection and incident coronary heart disease: the Atherosclerosis Risk in Communities Study. American Journal of Epidemiology 1999;150:149-56. Ref ID: 64 91. Gupta S. Chronic infection in the aetiology of atherosclerosis--focus on Chlamydia pneumoniae. [Review] [73 refs]. Atherosclerosis 1999;143:1-6. Ref ID: 65 92. Tiran A, Tio RA, Ossewaarde JM, Tiran B, den Heijer P, The TH et al. Coronary angioplasty induces rise in Chlamydia pneumoniae-specific antibodies. Journal of Clinical Microbiology 1999;37:1013-7. Ref ID: 66 93. Fagerberg B, Gnarpe J, Gnarpe H, Agewall S, Wikstrand J. Chlamydia pneumoniae but not cytomegalovirus antibodies are associated with future risk of stroke and cardiovascular disease: a prospective study in middle-aged to elderly men with treated hypertension. Stroke 1999;30:299-305. Ref ID: 67 94. Nobel M, De Torrente A, Peter O, Genne D. No serological evidence of association between chlamydia pneumonia infection and acute coronary heart disease. Scandinavian Journal of Infectious Diseases 1999;31:261-4. Ref ID: 68 192 95. Gupta S,.Camm AJ. Chlamydia pneumoniae, antimicrobial therapy and coronary heart disease: a critical overview. [Review] [40 refs]. Coronary Artery Disease 1998;9:339- 43. Ref ID: 69 96. Andreasen JJ, Farholt S, Jensen JS. Failure to detect Chlamydia pneumoniae in calcific and degenerative arteriosclerotic aortic valves excised during open heart surgery. APMIS 1998;106:717-20. Ref ID: 70 97. Gupta S,.Camm AJ. Is there an infective aetiology to atherosclerosis?. [Review] [57 refs]. Drugs & Aging 1998;13:1-7. Ref ID: 71 98. Erdei A, Simon G, Hovanecz K. [Chlamydia pneumoniae infection in patients with myocardial infarct and angina pectoris]. [Hungarian]. Orvosi Hetilap 1998;139:1909-11. Ref ID: 72 99. Dahlen GH,.Stenlund H. Lp(a) lipoprotein is a major risk factor for cardiovascular disease: pathogenic mechanisms and clinical significance. Clinical Genetics 1997;52:272-80. Ref ID: 73 100. Lindberg G, Rastam L, Lundblad A, Sorlie PD, Folsom AR. The association between serum sialic acid and asymptomatic carotid atherosclerosis is not related to antibodies to herpes type viruses or Chlamydia pneumoniae. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. International Journal of Epidemiology 1997;26 :1386-91. Ref ID: 74 101. Nystrom-Rosander C, Thelin S, Hjelm E, Lindquist O, Pahlson C, Friman G. High incidence of Chlamydia pneumoniae in sclerotic heart valves of patients undergoing aortic valve replacement. Scandinavian Journal of Infectious Diseases 1997;29:361-5. Ref ID: 75 102. Gupta S,.Camm AJ. Chronic infection in the etiology of atherosclerosis--the case for Chlamydia pneumoniae. [Review] [68 refs]. Clinical Cardiology 1997;20:829-36. Ref ID: 76 103. Gurfinkel E, Bozovich G, Daroca A, Beck E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group [see comments]. Lancet 1997;350:404-7. Ref ID: 77 104. Ellis RW. Infection and coronary heart disease. [Review] [44 refs]. Journal of Medical Microbiology 1997;46:535-9. Ref ID: 78 105. Miettinen H, Lehto S, Saikku P, Haffner SM, Ronnemaa T, Pyorala K et al. Association of Chlamydia pneumoniae and acute coronary heart disease events in non-insulin dependent diabetic and non-diabetic subjects in Finland [see comments]. European Heart Journal 1996;17:682-8. Ref ID: 79 193 106. Muhlestein JB, Hammond EH, Carlquist JF, Radicke E, ThoMSon MJ, Karagounis LA et al. Increased incidence of Chlamydia species within the coronary arteries of patients with symptomatic atherosclerotic versus other forms of cardiovascular disease. Journal of the American College of Cardiology 1996;27:1555-61. Ref ID: 80 107. Mendall MA, Patel P, Ballam L, Strachan D, Northfield TC. C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study [see comments]. BMJ 1996;312:1061-5. Ref ID: 81 108. Melnick SL, Shahar E, Folsom AR, Grayston JT, Sorlie PD, Wang SP et al. Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators. American Journal of Medicine 1993;95:499-504. Ref ID: 82 109. Saikku P, Leinonen M, Tenkanen L, Linnanmaki E, Ekman MR, Manninen V et al. Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study [see comments]. Annals of Internal Medicine 1992; 116:273-8. Ref ID: 83 110. Choussat R, Montalescot G, Collet J, Jardel C, Ankri A, Fillet A et al. Effect of prior exposure to Chlamydia pneumoniae, Helicobacter pylori, or cytomegalovirus on the degree of inflammation and one-year prognosis of patients with unstable angina pectoris or non-Q-wave acute myocardial infarction. American Journal of Cardiology 2000;86:379-84. Ref ID: 110 111. Jackson LA. Description and status of the azithromycin and coronary events study (ACES). Journal of Infectious Diseases 2000;181 Suppl 3:S579-S581. Ref ID: 111 112. Grabczewska Z,.Nartowicz E. [Infections with Chlamydia pneumoniae, Helicobacter pylori or cytomegalovirus and atherosclerosis]. [Review] [37 refs] [Polish]. Przeglad Lekarski 1999;56:584-7. Ref ID: 112 113. Dunne M. WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics. [Review] [5 refs]. American Heart Journal 1999;138:S542- S544. Ref ID: 113 114. Danesh J. Coronary heart disease, Helicobacter pylori, dental disease, Chlamydia pneumoniae, and cytomegalovirus: meta-analyses of prospective studies. American Heart Journal 1999;138:S434-S437. Ref ID: 114 115. Melissano G, Blasi F, Esposito G, Tarsia P, Dordoni L, Arosio C et al. Chlamydia pneumoniae eradication from carotid plaques. Results of an open, randomised treatment study. European Journal of Vascular & Endovascular Surgery 1999;18:355-9. Ref ID: 115 194 116. Nieto FJ, Folsom AR, Sorlie PD, Grayston JT, Wang SP, Chambless LE. Chlamydia pneumoniae infection and incident coronary heart disease: the Atherosclerosis Risk in Communities Study. American Journal of Epidemiology 1999;150:149-56. Ref ID: 116 117. Fagerberg B, Gnarpe J, Gnarpe H, Agewall S, Wikstrand J. Chlamydia pneumoniae but not cytomegalovirus antibodies are associated with future risk of stroke and cardiovascular disease: a prospective study in middle-aged to elderly men with treated hypertension. Stroke 1999;30:299-305. Ref ID: 117 118. Miettinen H, Lehto S, Saikku P, Haffner SM, Ronnemaa T, Pyorala K et al. Association of Chlamydia pneumoniae and acute coronary heart disease events in non-insulin dependent diabetic and non-diabetic subjects in Finland [see comments]. European Heart Journal 1996;17:682-8. Ref ID: 118 119. Berdal BP,.Scheel O. [Chlamydia pneumoniae--pathogenesis and perspectives]. [Review] [19 refs] [Norwegian]. Tidsskrift for Den Norske Laegeforening 1993;113:859-61. Ref ID: 119 120. Saikku P, Leinonen M, Tenkanen L, Linnanmaki E, Ekman MR, Manninen V et al. Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study [see comments]. Annals of Internal Medicine 1992; 116:273-8. Ref ID: 120 121. Qavi HB, Melnick JL, Adam E, Debakey ME. Frequency of coexistence of cytomegalovirus and Chlamydia pneumoniae in atherosclerotic plaques. Central European Journal of Public Health 2000;8:71-3. Ref ID: 121 122. Kaykov E, Abbou B, Friedstrom S, Hermoni D, Roguin N. Chlamydia preumoniae in ischemic heart disease [see comments]. Israel Medical Association Journal: IMAJ 1999;1:225-7. Ref ID: 122 123. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta analysis [see comments]. BMJ 2000;321:208-13. Ref ID: 123 124. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses [see comments]. BMJ 2000;321:199-204. Ref ID: 124 125. Higuchi M, Castelli JB, Aiello VD, Palomino S, Reis MM, Sambiase NV et al. Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arquivos Brasileiros de Cardiologia 2000;74:149-51. Ref ID: 125 126 Glader CA, Boman J, Saikku P, Stenlund H, Weinehall L, Hallmanns G et al. The proatherogenic properties of lipoprotein(a) may be enhanced through the formation of circulating immune complexes containing Chlamydia pneumoniae-specific IgG antibodies [see comments]. European Heart Journal 2000;21:639-46. Ref ID: 12 195 127. Kaftan AH,.Kaftan O. Coronary artery disease and infection with chlamydia pneumonia. Japanese Heart Journal 2000;41:165-72. 128. Wittwer T, Pethig K, Heublein B, Teebken OE, Harringer W, Haverich A et al. Impact of chronic infection with Chlamydia pneumoniae on incidence of cardiac allograft vasculopathy. Transplantation 2000;69:1962-4. Ref ID: 128 129. Lindholt JS, Vammen S, Lind I, Fasting H, Henneberg EW. The progression of lower limb atherosclerosis is associated with IgA antibodies against Chlamydia pneumoniae [published erratum appears in Eur J Vasc Endovasc Surg 2000 Mar;19(3):332]. European Journal of Vascular & Endovascular Surgery 1999;18:527-9. Ref ID: 129 130. Ammann P, Marschall S, Kraus M, Schmid L, Angehrn W, Krapf R et al. Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest 2000;117:333-8. Ref ID: 130 131. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000; 20:52-63. Ref ID: 131 132. Hoffmeister A, Rothenbacher D, Wanner P, Bode G, Persson K, Brenner H et al. Seropositivity to chlamydial lipopolysaccharide and Chlamydia pneumoniae, systemic inflammation and stable coronary artery disease: negative results of a case-control study. Journal of the American College of Cardiology 2000;35:112-8. Ref ID: 132 133. Abdelmouttaleb I, Danchin N, Ilardo C, Aimone-Gastin I, Angioi M, Lozniewski A et al. C-Reactive protein and coronary artery disease: additional evidence of the implication of an inflammatory process in acute coronary syndromes [see comments]. American Heart Journal 1999;137:346-51. Ref ID: 133 134. Leinonen M,.Saikku P. Interaction of Chlamydia pneumoniae infection with other risk factors of atherosclerosis. American Heart Journal 1999;138:S504-S506. Ref ID: 134 135. Cellesi C, Sansoni A, Casini S, Migliorini L, Zacchini F, Gasparini R et al. Chlamydia pneumoniae antibodies and angiographically demonstrated coronary artery disease in a sample population from Italy. Atherosclerosis 1999;145:81-5. Ref ID: 135 136. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999;81:245-7. Ref ID: 136 137. Bauriedel G, Welsch U, Likungu JA, Welz A, Luderitz B. [Chlamydia pneumoniae in coronary plaques: Increased detection with acute coronary syndrome]. [German]. Deutsche Medizinische Wochenschrift 1999;124:375-80. Ref ID: 137 196 138. Altman R, Rouvier J, Scazziota A, Absi RS, Gonzalez C. Lack of association between prior infection with Chlamydia pneumoniae and acute or chronic coronary artery disease. Clinical Cardiology 1999;22:85-90. Ref ID: 138 139. Leowattana W, Mahanonda N, Bhuripunyo K, Leelarasamee A, Pokum S, Suwimol B. The prevalence of Chlamydia pneumoniae antibodies in Thai patients with coronary artery disease. Journal of the Medical Association of Thailand 1999;82:792-7. Ref ID: 139 140. Nobel M, De Torrente A, Peter O, Genne D. No serological evidence of association between chlamydia pneumonia infection and acute coronary heart disease. Scandinavian Journal of Infectious Diseases 1999;31:261-4. Ref ID: 140 141. Miyashita N, Toyota E, Sawayama T, Matsumoto A, Mikami Y, Kawai N et al. Association of chronic infection of Chlamydia pneumoniae and coronary heart disease in the Japanese. Internal Medicine 1998;37:913-6. Ref ID: 141 142. Fang JC, Kinlay S, Kundsin R, Ganz P. Chlamydia pneumoniae infection is frequent but not associated with coronary arteriosclerosis in cardiac transplant recipients. American Journal of Cardiology 1998;82:1479-83. Ref ID: 142 143. Ossewaarde JM, Feskens EJ, De Vries A, Vallinga CE, Kromhout D. Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not. Epidemiology & Infection 1998;120:93-9. Ref ID: 143 144. Spodick DH. More information on infection and infarction [letter; comment]. Chest 1998;113:558. Ref ID: 144 145. Dahlen GH,.Stenlund H. Lp(a) lipoprotein is a major risk factor for cardiovascular disease: pathogenic mechanisms and clinical significance. Clinical Genetics 1997;52:272-80. Ref ID: 145 146. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Chlamydia pneumoniae and Helicobacter pylori infections in Sami and Finnish reindeer herders. International Journal of Circumpolar Health 1997;56:70-5. Ref ID: 146 147. Wimmer ML, Sandmann-Strupp R, Saikku P, Haberl RL. Association of chlamydial infection with cerebrovascular disease. Stroke 1996;27:2207-10. Ref ID: 147 148. Kuo CC, Grayston JT, Campbell LA, Goo YA, Wissler RW, Benditt EP. Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old). Proceedings of the National Academy of Sciences of the United States of America 1995;92:6911-4. Ref ID: 148 197 149. Melnick SL, Shahar E, Folsom AR, Grayston JT, Sorlie PD, Wang SP et al. Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators. American Journal of Medicine 1993;95:499-504. Ref ID: 149 150. Thom DH, Grayston JT, Siscovick DS, Wang SP, Weiss NS, Daling JR. Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease. JAMA 1992;268:68-72. Ref ID: 150 151. Thom DH, Wang SP, Grayston JT, Siscovick DS, Stewart DK, Kronmal RA et al. Chlamydia pneumoniae strain TWAR antibody and angiographically demonstrated coronary rtery disease. Arteriosclerosis & Thrombosis 1991;11:547-51. Ref ID: 151 152. Arbustini E, Morbini P, Bello BD, Prati F, Specchia G. From plaque biology to clinical setting [see comments]. [Review] [60 refs]. American Heart Journal 1999;138:S55- S60. Ref ID: 152 153. Famularo G, Trinchieri V, Santini G, De Simone C. Infections, atherosclerosis, and coronary heart disease. [Review] [115 refs]. Annali Italiani di Medicina Interna 2000;15:144- 55. Ref ID: 153 154. Fong IW. Emerging relations between infectious diseases and coronary artery disease and atherosclerosis. [Review] [95 refs]. CMAJ 2000;163:49-56. Ref ID: 154 155. Silva Neto LB,.Ribeiro JP. Infectious agents in coronary atherosclerosis. [Review] [24 refs]. Arquivos Brasileiros de Cardiologia 1999;73:455-62. Ref ID: 155 156. Rosen H, Muhlestein JB, Bartlett J, Chen S, Chikami G, Corson M et al. Collaborative multidisciplinary workshop report: clinical antimicrobial trials for primary and secondary prevention of atherosclerotic cardiovascular disease. [Review] [3 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S582-S584. Ref ID: 156 157. Gurfinkel E. Inflammation, infection, or both in atherosclerosis: the ROXIS trial in perspective. [Review] [13 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S566-S568. Ref ID: 157 158. Meier CR. Antibiotics in the prevention and treatment of coronary heart disease. [Review] [61 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S558-S562. Ref ID: 158 159. Muhlestein JB. Chlamydia pneumoniae-induced atherosclerosis in a rabbit model. [Review] [6 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S505-S507. Ref ID: 159 198 160. Rosenfeld ME, Blessing E, Lin TM, Moazed TC, Campbell LA, Kuo C. Chlamydia, inflammation, and atherogenesis. [Review] [53 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S492-S497. Ref ID: 160 161. Kalayoglu MV, Indrawati, Morrison RP, Morrison SG, Yuan Y, Byrne GI. Chlamydial virulence determinants in atherogenesis: the role of chlamydial lipopolysaccharide and heat shock protein 60 in macrophage-lipoprotein interactions. [Review] [41 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S483-S489. Ref ID: 161 162. Summersgill JT, Molestina RE, Miller RD, Ramirez JA. Interactions of Chlamydia pneumoniae with human endothelial cells. [Review] [18 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S479-S482. Ref ID: 162 163. Gaydos CA. Growth in vascular cells and cytokine production by Chlamydia pneumoniae. [Review] [39 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S473- S478. Ref ID: 163 164. Boman J,.Gaydos CA. Polymerase chain reaction detection of Chlamydia pneumoniae in circulating white blood cells. [Review] [23 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S452-S454. Ref ID: 164 165. Taylor-Robinson D,.Thomas BJ. Chlamydia pneumoniae in atherosclerotic tissue. [Review] [34 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S437-S440. Ref ID: 165 166. Siscovick DS, Schwartz SM, Caps M, Wang SP, Grayston JT. Chlamydia pneumoniae and atherosclerotic risk in populations: the role of seroepidemiology. [Review] [26 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S417-S420. Ref ID: 166 167. Leinonen M. Chlamydia pneumoniae and other risk factors for atherosclerosis. [Review] [35 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S414-S416. Ref ID: 167 168. Saikku P. Epidemiologic association of Chlamydia pneumoniae and atherosclerosis: the initial serologic observation and more. [Review] [21 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S411-S413. Ref ID: 168 169. Grayston JT. Background and current knowledge of Chlamydia pneumoniae and atherosclerosis. [Review] [74 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S402- S410. Ref ID: 169 170. Ewald PW,.Cochran GM. Chlamydia pneumoniae and cardiovascular disease: an evolutionary perspective on infectious causation and antibiotic treatment. [Review] [45 refs]. Journal of Infectious Diseases 2000;181 Suppl 3:S394-S401. Ref ID: 170 199 171. Camm AJ,.Fox KM. Chlamydia pneumonia (and other infective agents) in atherosclerosis and acute coronary syndromes. How good is the evidence?. [Review] [49 refs]. European Heart Journal 2000;21:1046-51. Ref ID: 171 172. Campbell LA, Rosenfeld M, Kuo CC. The role of Chlamydia pneumoniae in atherosclerosis--recent evidence from animal models. [Review] [12 refs]. Trends in Microbiology 2000;8:255-7. Ref ID: 172 173. Wong CK, Amos DJ, White HD. Does infection have a role in the pathogenesis of coronary artery disease?. [Review] [53 refs]. New Zealand Medical Journal 2000;113:190-2. Ref ID: 173 174. Benitez RM. Atherosclerosis: an infectious disease?. [Review] [12 refs]. Hospital Practice (Office Edition) 1985;34:79-82. Ref ID: 174 175. Leinonen M,.Saikku P. Infections and atherosclerosis. [Review] [118 refs]. Scandinavian Cardiovascular Journal 2000;34:12-20. Ref ID: 175 176. Hansson GK, Zhou X, Tornquist E, Paulsson G. The role of adaptive immunity in atherosclerosis. [Review] [83 refs]. Annals of the New York Academy of Sciences 2000;902:53-62. Ref ID: 176 177. Wick G. Atherosclerosis--an autoimmune disease due to an immune reaction against heat-shock protein 60. [Review] [23 refs]. Herz 2000;25:87-90. Ref ID: 177 178. Haberbosch W,.Jantos C. Chlamydia pneumoniae infection is not an independent risk factor for arterial disease. [Review] [33 refs]. Herz 2000;25:79-83. Ref ID: 178 179. High KP. Atherosclerosis and infection due to Chlamydia pneumoniae or cytomegalovirus: weighing the evidence. [Review] [42 refs]. Clinical Infectious Diseases 1999;28:746-9. Ref ID: 179 180. Hammerschlag MR. Activity of gemifloxacin and other new quinolones against Chlamydia pneumoniae: a review. [Review] [33 refs]. Journal of Antimicrobial Chemotherapy 2000;45 Suppl 1:35-9. Ref ID: 180 181. Sinha N,.Garg N. Role of infections in the pathogenesis of atherosclerotic coronary artery disease: past, present and future. [Review] [49 refs]. Indian Heart Journal 2000;52:79- 85. Ref ID: 181 182. Saikku P. Chlamydia pneumoniae in atherosclerosis. [Review] [66 refs]. Journal of Internal Medicine 2000;247:391-6. Ref ID: 182 200 183. Ouchi K. Chlamydia pneumoniae and atherosclerosis. [Review] [54 refs]. Japanese Journal of Infectious Diseases 1999;52:223-7. Ref ID: 183 184. Chico TJ,.Crossman DC. Key developments in unstable angina. [Review] [16 refs]. Practitioner 712;243:706-9. Ref ID: 184 185. de Boer OJ, van der Wal AC, Becker AE. Atherosclerosis, inflammation, and infection. [Review] [64 refs]. Journal of Pathology 2000;190:237-43. Ref ID: 185 186. Taylor-Robinson D,.Thomas BJ. Chlamydia pneumoniae in arteries: the facts, their interpretation, and future studies [see comments]. [Review] [46 refs]. Journal of Clinical Pathology 1998;51:793-7. Ref ID: 186 187. Hammerschlag MR. Chlamydia pneumoniae and atherosclerosis: what we know and what we don't know. [Review] [16 refs]. Pediatric Infectious Disease Journal 2000;19:75-6. Ref ID: 187 188. Muhlestein JB. Chronic infection and coronary artery disease. [Review] [129 refs]. Medical Clinics of North America 2000;84:123-48. Ref ID: 188 189. Puolakkainen M,.Makela PH. Vaccination against infections by Chlamydia pneumoniae. [Review] [64 refs]. Comptes Rendus de l Academie des Sciences - Serie Iii, Sciences de la Vie 1999;322:973-8. Ref ID: 189 190. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000; 20:52-63. Ref ID: 190 191. Cook PJ. Antimicrobial therapy for Chlamydia pneumoniae: its potential role in atherosclerosis and asthma. [Review] [51 refs]. Journal of Antimicrobial Chemotherapy 199944:145-8. Ref ID: 191 192. Smith D, Gupta S, Kaski JC. Chronic infections and coronary heart disease. [Review] [87 refs]. International Journal of Clinical Practice 1999;53:460-6. Ref ID: 192 193. Capron L. How to design vaccination trials to prevent atherosclerosis. [Review] [2 refs]. American Heart Journal 1999;138:S558-S559. Ref ID: 193 194. Grayston JT. Design of future intervention studies for Chlamydia pneumoniae in atherosclerosis. [Review] [1 refs]. American Heart Journal 1999;138:S556-S557. Ref ID: 194 195. Campbell LA. How to design studies to confirm a link between bacterial infection and atherosclerosis. [Review] [21 refs]. American Heart Journal 1999;138:S552-S553. Ref ID: 195 201 196. O'Connor S. Fulfillment of Koch's postulates and the causes of atherosclerosis. [Review] [4 refs]. American Heart Journal 1999;138:S550-S551. Ref ID: 196 197. Grayston JT, Jackson LA, Kennedy WJ, Kronmal RA. Secondary prevention trials for coronary artery disease with antibiotic treatment for Chlamydia pneumoniae: design issues. [Review] [10 refs]. American Heart Journal 1999;138:S545-S549. Ref ID: 197 198. Dunne M. WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics. [Review] [5 refs]. American Heart Journal 1999;138:S542- S544. Ref ID: 198 199. Gupta S. Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. [Review] [13 refs]. American Heart Journal 1999;138:S539-S541. Ref ID: 199 200. Gurfinkel EP,.Bozovich G. Emerging role of antibiotics in atherosclerosis. [Review] [21 refs]. American Heart Journal 1999;138:S537-S538. Ref ID: 200 201. Saikku P. Epidemiology of Chlamydia pneumoniae in atherosclerosis. [Review] [38 refs]. American Heart Journal 1999;138:S500-S503. Ref ID: 201 202. Kuo CC. Pathologic manifestation of Chlamydial infection. [Review] [41 refs]. American Heart Journal 1999;138:S496-S499. Ref ID: 202 203. Kol A,.Libby P. Molecular mediators of arterial inflammation: a role for microbial products?. [Review] [11 refs]. American Heart Journal 1999;138:S450-S452. Ref ID: 203 204. Valtonen VV. Role of infections in atherosclerosis. [Review] [12 refs]. American Heart Journal 1999; 138:S431-S433. Ref ID: 204 205. Shor A,.Phillips JI. Chlamydia pneumoniae and atherosclerosis. [Review] [42 refs]. JAMA 1999;282:2071-3. Ref ID: 205 206. Hammerschlag MR. Activity of quinolones against Chlamydia pneumoniae. [Review] [37 refs]. Drugs 1999;58 Suppl 2:78-81. Ref ID: 206 207. Meier CR. The possible role of infections in acute myocardial infarction. [Review] [97 refs]. Biomedicine & Pharmacotherapy 1999;53:397-404. Ref ID: 207 208. Grayston JT. Does Chlamydia pneumoniae cause atherosclerosis?. [Review] [43 refs]. Archives of Surgery 1999;134:930-4. Ref ID: 208 202 209. Movahed MR. Infection with Chlamydia pneumoniae and atherosclerosis: a review. [Review] [49 refs]. Journal - South Carolina Medical Association 1999;95:303-8. Ref ID: 209 210. Carlisle SS,.Nahata MC. Chlamydia pneumoniae and coronary heart disease. [Review] [74 refs]. Annals of Pharmacotherapy 1999;33:615-22. Ref ID: 210 211. Epstein SE, Zhou YF, Zhu J. Infection and atherosclerosis: emerging mechanistic paradigms. [Review] [130 refs]. Circulation 1999;100:e20-e28. Ref ID: 211 212. LaVerda D, Kalayoglu MV, Byrne GI. Chlamydial heat shock proteins and disease pathology: new paradigMS for old problems?. [Review] [48 refs]. Infectious Diseases in Obstetrics & Gynecology 1999;7:64-71. Ref ID: 212 213. Gupta S. Chronic infection in the aetiology of atherosclerosis--focus on Chlamydia pneumoniae. [Review] [73 refs]. Atherosclerosis 1999;143:1-6. Ref ID: 213 214. Schussheim AE,.Fuster V. Antibiotics for myocardial infarction? A possible role of infection in atherogenesis and acute coronary syndromes. [Review] [52 refs]. Drugs 1999;57:283-91. Ref ID: 214 215. Wong YK, Gallagher PJ, Ward ME. Chlamydia pneumoniae and atherosclerosis. [Review] [88 refs]. Heart 1999;81:232-8. Ref ID: 215 216. Lindholt JS, Fasting H, Henneberg EW, Ostergaard L. A review of Chlamydia pneumoniae and atherosclerosis. [Review] [57 refs]. European Journal of Vascular & Endovascular Surgery 1999;17:283-9. Ref ID: 216 217. Juvonen T, Juvonen J, Savolainen MJ. Is vasculitis a significant component of atherosclerosis?. [Review] [93 refs]. Current Opinion in Rheumatology 1999;11:3-10. Ref ID: 217 218. Kuvin JT,.Kimmelstiel CD. Infectious causes of atherosclerosis. [Review] [56 refs]. American Heart Journal 1999;137:216-26. Ref ID: 218 219. Behbahani R, Verme-Gibboney C, Romanelli AM. Chlamydia pneumoniae and anti infective therapy: their role in the pathogenesis and treatment of coronary artery disease. [Review] [58 refs]. Clinical Therapeutics 1999;21:1286-300. Ref ID: 219 220. Cammarota G, Pasceri V, Papa A, Cianci R, Gasbarrini A, Fedeli P et al. Helicobacter pylori infection and ischaemic heart disease. [Review] [12 refs]. Italian Journal of Gastroenterology & Hepatology 1998;30 Suppl 3:S304-S306. Ref ID: 220 203 221. Cheng JW,.Rivera NG. Infection and atherosclerosis--focus on cytomegalovirus and Chlamydia pneumoniae. [Review] [47 refs]. Annals of Pharmacotherapy 1998;32:1310-6. Ref ID: 221 222. Campbell LA, Kuo CC, Grayston JT. Chlamydia pneumoniae and cardiovascular disease. [Review] [53 refs]. Emerging Infectious Diseases 1998;4:571-9. Ref ID: 222 223. Taylor-Robinson D. Chlamydia pneumoniae in vascular tissue. [Review] [22 refs]. Atherosclerosis 1998;140 Suppl 1:S21-S24. Ref ID: 223 224. Noll G. Pathogenesis of atherosclerosis: a possible relation to infection. [Review] [31 refs]. Atherosclerosis 1998;140 Suppl 1:S3-S9. Ref ID: 224 225. Gurfinkel E,.Bozovich G. Chlamydia pneumoniae: inflammation and instability of the atherosclerotic plaque. [Review] [31 refs]. Atherosclerosis 1998;140 Suppl 1:S31-S35. Ref ID: 225 226. Orfila JJ. Seroepidemiological evidence for an association between Chlamydia pneumoniae and atherosclerosis. [Review] [24 refs]. Atherosclerosis 1998;140 Suppl 1:S11- S15. Ref ID: 226 227. Gupta S,.Camm AJ. Chlamydia pneumoniae, antimicrobial therapy and coronary heart disease: a critical overview. [Review] [40 refs]. Coronary Artery Disease 1998;9:339- 43. Ref ID: 227 228. Muhlestein JB. Bacterial infections and atherosclerosis. [Review] [31 refs]. Journal of Investigative Medicine 1998;46:396-402. Ref ID: 228 229. Gupta S,.Camm AJ. Is there an infective aetiology to atherosclerosis?. [Review] [57 refs]. Drugs & Aging 1998;13:1-7. Ref ID: 229 230. Gibbs RG, Carey N, Davies AH. Chlamydia pneumoniae and vascular disease. [Review] [87 refs]. British Journal of Surgery 1998;85:1191-7. Ref ID: 230 231. Mandell GL,.Townsend GC. New and emerging infectious diseases. [Review] [39 refs]. Transactions of the American Clinical & Climatological Association 1998;109:205-16. Ref ID: 231 232. Pai J, Knoop FC, Hunter WJ, III, Agrawal DK. Chlamydia pneumoniae and occlusive vascular disease: identification and characterization. [Review] [75 refs]. Journal of Pharmacological & Toxicological Methods 1998;39:51-61. Ref ID: 232 233. Futterman LG,.Lemberg L. Fifty percent of patients with coronary artery disease do not have any of the conventional risk factors. [Review] [10 refs]. American Journal of Critical Care 1998;7:240-4. Ref ID: 233 204 234. Mehta JL, Saldeen TG, Rand K. Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease [see comments]. [Review] [97 refs]. Journal of the American College of Cardiology 1998;31:1217-25. Ref ID: 234 235. Mattila KJ, Valtonen VV, Nieminen MS, Asikainen S. Role of infection as a risk factor for atherosclerosis, myocardial infarction, and stroke. [Review] [203 refs]. Clinical Infectious Diseases 1998;26:719-34. Ref ID: 235 236. Leonard M. Calculus and coronary artery disease. [Review] [11 refs]. Dentistry Today 1997;16:82-5. Ref ID: 236 237. Libby P, Egan D, Skarlatos S. Roles of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. [Review] [91 refs]. Circulation 1997;96:4095-103. Ref ID: 237 238. Shafran SD,.Conley JM. Does Chlamydia pneumoniae cause coronary atherosclerosis and should we all take macrolides? [editorial]. [Review] [29 refs]. Canadian Journal of Cardiology 1997;13:1017-9. Ref ID: 238 239. Gupta S,.Camm AJ. Chronic infection in the etiology of atherosclerosis--the case for Chlamydia pneumoniae. [Review] [68 refs]. Clinical Cardiology 1997;20:829-36. Ref ID: 239 240. Saikku P. Chlamydia pneumoniae and atherosclerosis--an update. [Review] [41 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1997;104:53-6. Ref ID: 240 241. Halme S,.Surcel HM. Cell mediated immunity to Chlamydia pneumoniae. [Review] [37 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1997;104:18-21. Ref ID: 241 242. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? [see comments]. [Review] [62 refs]. Lancet 1997;350:430-6. Ref ID: 242 243. Ellis RW. Infection and coronary heart disease. [Review] [44 refs]. Journal of Medical Microbiology 1997;46:535-9. Ref ID: 243 244. Peeling RW,.Brunham RC. Chlamydiae as pathogens: new species and new issues. [Review] [78 refs]. Emerging Infectious Diseases 1996;2:307-19. Ref ID: 244 245. Cook PJ,.Lip GY. Infectious agents and atherosclerotic vascular disease. [Review] [127 refs]. QJM 1996;89:727-35. Ref ID: 245 246. Capron L. Chlamydia in coronary plaques--hidden culprit or harmless hobo?. [Review] [9 refs]. Nature Medicine 1996;2:856-7. Ref ID: 246 205 247. Ward ME. The immunobiology and immunopathology of chlamydial infections. [Review] [200 refs]. APMIS 1995;103:769-96. Ref ID: 247 248. Bourke SJ,.Lightfoot NF. Chlamydia pneumoniae: defining the clinical spectrum of infection requires precise laboratory diagnosis. [Review] [50 refs]. Thorax 1995;50 Suppl 1:S43-S48. Ref ID: 248 249. Nieminen MS, Mattila K, Valtonen V. Infection and inflammation as risk factors for myocardial infarction. [Review] [36 refs]. European Heart Journal 1993;14 Suppl K:12-6. Ref ID: 249 250. Leinonen M. Pathogenetic mechanisms and epidemiology of Chlamydia pneumoniae. [Review] [53 refs]. European Heart Journal 1993;14 Suppl K:57-61. Ref ID: 250 251. Grayston JT, Kuo CC, Campbell LA, Benditt EP. Chlamydia pneumoniae, strain TWAR and atherosclerosis. [Review] [23 refs]. European Heart Journal 1993;14 Suppl K:66-71. Ref ID: 251 252 Odeh M,.Oliven A. Chlamydial infections of the heart. [Review] [126 refs]. European Journal of Clinical Microbiology & Infectious Diseases 1992;11:885-93. Ref ID: 252 253 Valtonen VV. Infection as a risk factor for infarction and atherosclerosis. [Review] [58 refs]. Annals of Medicine 1991;23:539-43. Ref ID: 253 Chlamydia pneumoniae and Heart Disease - science citation index search 1 Appels A, Bar FW, Bar J, Bruggeman C, de Baets M. Inflammation, depressive symptomatology, and coronary artery disease. Psychosomatic Medicine 2000;62:601-5. 2 Bauer-Krylov E, Madeo M, Stille W. Infection as a possible explanation for the higher incidence of myocardial infaction in males. Deutsche Medizinische Wochenschrift 2000;125:1095-7. 3 Beuckelmann DJ. Coronary heart disease - An infection? Herz Kreislauf 1998;30:425-8. 4 Blanchard TJ,Mabey DCW. Chlamydial infections. British Journal Of Clinical Practice 1994;48 :201-5. 4 Cook PJ,.Honeybourne D. Chlamydia pneumoniae. Journal Of Antimicrobial Chemotherapy 1994;34:859-73. 6 Ekesbo R, Nilsson PM, Lindholm LH, Persson K, Wadstrom T. Combined seropositivity for H-pylori and C-pneumoniae is associated with age, obesity and social factors. Journal Of Cardiovascular Risk 2000;7:191-5. 7 Elkind MSV, Lin IF, Grayston JT, Sacco RL. Chlamydia pneumoniae and the risk of first ischemic stroke - The Northern Manhattan Stroke Study. Stroke 2000;31:1521-5. 206 8 Ericson K, Saldeen TGP, Lindquist O, Pahlson C, Mehta JL. Relationship of Chlamydia pneumoniae infection to severity of human coronary atherosclerosis. Circulation 2000;101:2568-71. 9 Gilbert DN. The potential etiologic role of Chlamydia pneumoniae in atherosclerosis - Preface. Journal Of Infectious Diseases 2000;181:S393-S393. 10 Gnarpe H, Gnarpe J, Gastrin B, Hallander H. Chlamydia pneumoniae and myocarditis. Scandinavian Journal Of Infectious Diseases 1997;50-2. 11 Grayston JT. What is needed to prove that Chlamydia pneumoniae does, or does not, play an etiologic role in atherosclerosis? Journal Of Infectious Diseases 2000;181:S585-S586. 12 Grimes DS, Hindle E, Dyer T. Respiratory infection and coronary heart disease: progression of a paradigm. Qjm-Monthly Journal Of The Association Of Physicians 2000;93:375-83. 13 Herbosch WH,.Jantos C. Chlamydia pneumoniae infection is not an independent risk factor for arterial disease. Herz 2000;25:79-83. 14 Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Symptoms of chronic bronchitis and the risk of coronary disease. Lancet 1996;348:567-72. 15 Karlsson L, Gnarpe J, Naas J, Olsson G, Lindholm J, Steen B et al. Detection of viable Chlamydia pneumoniae in abdominal aortic aneurysMS. European Journal Of Vascular And Endovascular Surgery 2000;19:630-5. 16 Kuo CC,.Campbell LA. Detection of Chlamydia pneumoniae in arterial tissues. Journal Of Infectious Diseases 2000;181:S432-S436. 17 Lamb DJ,.Ferns GAA. Infection, immunisation and atherosclerosis: is there a link? Vaccine 1999;17:559-64. 18 Lapetra J, Santos JM, Gil-Peralta A, Mayoral E, Gonzalez-Marcos JR. Chlamydia pneumoniae and atherosclerosis. Revista De Neurologia 1999;28:251-5. 19 Meier CR, Derby LE, Jick SS, Vasilakis C, Jick H. Antibiotics and risk of subsequent first-time acute myocardial infarction. Jama-Journal Of The American Medical Association 1999;281:427-31. 20 Quinn TC. Does Chlamydia pneumoniae cause coronary heart disease? Current Opinion In Infectious Diseases 1998;11:301-7. 21 Song YG, Kwon HM, Kim JM, Hong BK, Kim DS, Huh AJ et al. Serologic and histopathologic study of Chlamydia pneumoniae infection in atherosclerosis: A possible pathogenetic mechanism of atherosclerosis induced Chlamydia pneumoniae. Yonsei Medical Journal 2000;41:319-27. 22 Stille W,.Dittmann R. Atherosclerosis as consequence of chronic infection by Chlamydia pneumoniae. Herz 1998;23:185-92. 23 Theegarten D, Mogilevski G, Anhenn O, Stamatis G, Jaeschock R, Morgenroth K. The role of chlamydia in the pathogenesis of pulmonary emphysema - Electron microscopy and immunofluorescence reveal corresponding findings as in atherosclerosis. Virchows Archiv-An International Journal Of Pathology 2000;437:190-3. 207 24 Weiss SM, Roblin PM, Gaydos CA, Cummings P, Patton DL, Schulhoff N et al. Failure to detect Chlamydia pneumoniae in coronary atheromas of patients undergoing atherectomy. Journal Of Infectious Diseases 1996;173:957-62. BORRELIA Occupational relevance 1. Burek V, Misic-Mayerus L, Maretic T. Antibodies to Borrelia burgdorferi in various population groups in Croatia. Scandinavian Journal of Infectious Diseases 1992;24:683-4. Ref ID: 312 2. Christiann F, Rayet P, Patey O, Lafaix C. Epidemiology of Lyme disease in France: Lyme borreliosis in the region of Berry sud: a six year retrospective. European Journal of Epidemiology 1996;12:479-83. Ref ID: 156 3. Christiann F, Rayet P, Patey O, Ngueodjibaye DB, Theron-le Gargasson JF, Lafaix C. Lyme borreliosis in central France: a sero-epidemiologic examination involving hunters [letter]. European Journal of Epidemiology 1997;13:855. Ref ID: 117 4. Hauser U, Krahl H, Peters H, Fingerle V, Wilske B. Impact of strain heterogeneity on Lyme disease serology in Europe: comparison of enzyme-linked immunosorbent assays using different species of Borrelia burgdorferi sensu lato. Journal of Clinical Microbiology 1998;36:427-36. Ref ID: 98 5. Ikushima M, Yamada F, Kawahashi S, Okuyama Y, Matsui K. Antibody response to OspC-I synthetic peptide derived from outer surface protein C of Borrelia burgdorferi in sera from Japanese forestry workers. Epidemiology And Infection 1999;122:429-33. Ref ID: 151 6. Jirous J, Pokorny J, Zastera M, Doutlik S, Bojar M. First experience with ELISA serosurvey for tick-borne borreliosis (Lyme disease) in Czechoslovakia. Journal of Hygiene, Epidemiology, Microbiology & Immunology 1988;32:169-72. Ref ID: 881 7. Kuiper H, de Jongh BM, Nauta AP, Houweling H, Wiessing LG, Moll V et al. Lyme borreliosis in Dutch forestry workers. Journal of Infection 1991;23:279-86. Ref ID: 4151 8. Kuiper H, Van Dam AP, Moll van Charante AW, Nauta NP, Dankert J. One year follow-up study to assess the prevalence and incidence of Lyme borreliosis among Dutch forestry workers. European Journal of Clinical Microbiology & Infectious Diseases 1993;12 :413-8. Ref ID: 294 9. Munchhoff P, Wilske B, Preac-Mursic V, Schierz G. Antibodies against Borrelia burgdorferi in Bavarian forest workers. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene - Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology 1987;263:412-9. Ref ID: 486 208 10. Nadal D, Wunderli W, Briner H, Hansen K. Prevalence of antibodies to Borrelia burgdorferi in forestry workers and blood donors from the same region in Switzerland. European Journal of Clinical Microbiology & Infectious Diseases 1989;8:992-5. Ref ID: 387 11. Nubling M, Rieger MA, Wangerin W, Batsford S, Tiller FW, Hofmann F. Occupational risk of infections with Borrelia burgdorferi in agricultural and forestry workers? Zentralblatt Fur Bakteriologie-International Journal Of Medical Microbiology Virology Parasitology And Infectious Diseases 1999;289:720-4. Ref ID: 4529 12. Nuti M, Amaddeo D, Crovatto M, Ghionni A, Polato D, Lillini E et al. Infections in an Alpine environment: antibodies to hantaviruses, leptospira, rickettsiae, and Borrelia burgdorferi in defined Italian populations. American Journal of Tropical Medicine & Hygiene 1993;48:20-5. Ref ID: 306 13. Oteo JA, Martinez dA, V, Casas J, Lozano A, Fernandez Calvo JL, Grandival R. Epidemiology and prevalence of seropositivity against Borrelia burgdorferi antigen in La Rioja, Spain. Revue d Epidemiologie et de Sante Publique 1992;40:85-92. Ref ID: 324 14. Rath PM, Ibershoff B, Mohnhaupt A, Albig J, Eljaschewitsch B, Jurgens D et al. Seroprevalence of lyme borreliosis in forestry workers from Brandenburg, Germany. European Journal of Clinical Microbiology & Infectious Diseases 1996;15:372-7. Ref ID: 4548 15. Santino I, Iori A, Sessa R, Sulli C, Favia G, Del Piano M. Borrelia burgdorferi s.l. and Ehrlichia chaffeensis in the National Park of Abruzzo. FEMS Microbiology Letters 1998;164:1-6. Ref ID: 2403 16. Schwartz BS, Goldstein MD, Childs JE. Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers. American Journal of Public Health 1993;83:1746-8. Ref ID: 281 17. Stanchi NO,.Balague LJ. Lyme disease: antibodies against Borrelia burgdorferi in farm workers in Argentina. Revista de Saude Publica 1993;27:305-7. Ref ID: 686 18. Vos K, Van Dam AP, Kuiper H, Bruins H, Spanjaard L, Dankert J. Seroconversion for Lyme borreliosis among Dutch military. Scandinavian Journal of Infectious Diseases 1994;26:427-34. Ref ID: 171 19. Welch DF, Carroll KC, Hofmeister EK, Persing DH, Robison DA, Steigerwalt et al. Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice. Journal of Clinical Microbiology 1999;37:2598-601. Ref ID: 682 20. Zhioua E, Rodhain F, Binet P, Perez-Eid C. Prevalence of antibodies to Borrelia burgdorferi in forestry workers of Ile de France, France. European Journal of Epidemiology 1997;13:959-62. Ref ID: 4620 209 21. Ahkee S,.Ramirez J. A case of concurrent Lyme meningitis with ehrlichiosis. Scandinavian Journal of Infectious Diseases 1996;28:527-8. 22. Ai CX, Zhang WF, Zhao JH. Sero-epidemiology of Lyme disease in an endemic area in China. Microbiology & Immunology 1994;38:505-9. Ref ID: 270 23. Baird AG, Gillies JC, Bone FJ, Dale BA, Miscampbell NT. Prevalence of antibody indicating Lyme disease in farmers in Wigtownshire [published erratum appears in BMJ 1989 Nov 11;299(6709):1206] [see comments]. BMJ 1989;299:836-7. Ref ID: 928 24. Baxter MA,.Wright AD. Prevalence of antibody indicating Lyme disease in farmers in Wigtownshire [letter; comment]. BMJ 1989;299:1221. Ref ID: 923 25. Defer G, Levy R, Brugieres P, Postic D, Degos JD. Lyme disease presenting as a stroke in the vertebrobasilar territory: MRI. Neuroradiology 1993;35:529-31. Ref ID: 283 26. Hoffmann JC, Stichtenoth DO, Zeidler H, Follmann M, Brandis A, Stanek G et al. Lyme disease in a 74-year-old forest owner with symptoms of dermatomyositis. Arthritis & Rheumatism 1995;38:1157-60. Ref ID: 227 27. Nakama H, Muramatsu K, Uchikama K, Yamagishi T. Possibility of Lyme disease as an occupational disease-- seroepidemiological study of regional residents and forestry workers. Asia-Pacific Journal of Public Health 1994;7:214-7. Ref ID: 198 28. Rees DHE,.Axford JS. Evidence for Lyme disease in urban park workers: A potential new health hazard for city inhabitants. British Journal of Rheumatology 1994;33:123-8. Ref ID: 2042 29. Schwartz BS,.Goldstein MD. Lyme disease in outdoor workers: risk factors, preventive measures, and tick removal methods [see comments]. American Journal of Epidemiology 1990;131:877-85. Ref ID: 376 30. Smith PF, Benach JL, White DJ, Stroup DF, Morse DL. Occupational risk of Lyme disease in endemic areas of New York State. Annals of the New York Academy of Sciences 1988;539:289-301. Ref ID: 525 BORRELIA AND CHRONIC DISEASE Borrelia and Chronic Health Effects – medline search (using filters) 1. Treib J, Grauer MT, Haass A, Langenbach J, Holzer G, Woessner R. Chronic fatigue syndrome in patients with Lyme borreliosis. European Neurology 2000;43:107-9. Ref ID: 123 210 2. Oschmann P, Dorndorf W, Hornig C, Schafer C, Wellensiek HJ, Pflughaupt et al. Stages and syndromes of neuroborreliosis. Journal of Neurology 1998;245:262-72. Ref ID: 124 3. Donta ST. Tetracycline therapy for chronic Lyme disease. Clinical Infectious Diseases 1997;25 Suppl 1:S52-S56. Ref ID: 125 4. Caperton EM, Heim-Duthoy KL, Matzke GR, Peterson PK, Johnson RC. Ceftriaxone therapy of chronic inflammatory arthritis. A double-blind placebo controlled trial. Archives of Internal Medicine 1990;150:1677-82. Ref ID: 127 5. Weber K, Preac-Mursic V, Neubert U, Thurmayr R, Herzer P, Wilske B et al. Antibiotic therapy of early European Lyme borreliosis and acrodermatitis chronica atrophicans. Annals of the New York Academy of Sciences 1988;539:324-45. Ref ID: 128 6. Treib J, Grauer MT, Haass A, Langenbach J, Holzer G, Woessner R. Chronic fatigue syndrome in patients with Lyme borreliosis. European Neurology 2000;43:107-9. Ref ID: 1 7. Oschmann P, Dorndorf W, Hornig C, Schafer C, Wellensiek HJ, Pflughaupt et al. Stages and syndromes of neuroborreliosis. Journal of Neurology 1998;245:262-72. Ref ID: 2 8. Peltomaa M, Saxen H, Pyykko I. Pediatric facial paralysis--a spirochetal infection with good prognosis? Acta Oto-Laryngologica - Supplement 1997;529:116-8. Ref ID: 3 9. Fawcett PT, Rose CD, Gibney KM, Doughty RA. Correlation of seroreactivity with response to antibiotics in pediatric Lyme borreliosis. Clinical & Diagnostic Laboratory Immunology 1997;4:85-8. Ref ID: 4 10. Gerber MA, Shapiro ED, Burke GS, Parcells VJ, Bell GL. Lyme disease in children in southeastern Connecticut. Pediatric Lyme Disease Study Group [see comments]. New England Journal of Medicine 1996;335:1270-4. Ref ID: 5 11. Huppertz HI, Karch H, Suschke HJ, Doring E, Ganser G, Thon A et al. Lyme arthritis in European children and adolescents. The Pediatric Rheumatology Collaborative Group. Arthritis & Rheumatism 1995;38:361-8. Ref ID: 6 12. Kuiper H, de Jongh BM, van Dam AP, Dodge DE, RaMSelaar AC, Spanjaard L et al. Evaluation of central nervous system involvement in Lyme borreliosis patients with a solitary erythema migrans lesion. European Journal of Clinical Microbiology & Infectious Diseases 1994;13:379-87. Ref ID: 7 13. Burdge DR,.O'Hanlon DP. Experience at a referral center for patients with suspected Lyme disease in an area of nonendemicity: first 65 patients. Clinical Infectious Diseases 1993;16:558-60. Ref ID: 8 211 14. Hansen K,.Lebech AM. The clinical and epidemiological profile of Lyme neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain 1992;115:399-423. Ref ID: 9 15. Logigian EL, Kaplan RF, Steere AC. Chronic neurologic manifestations of Lyme disease [see comments]. New England Journal of Medicine 1990;323:1438-44. 16. Caperton EM, Heim-Duthoy KL, Matzke GR, Peterson PK, Johnson RC. Ceftriaxone therapy of chronic inflammatory arthritis. A double-blind placebo controlled trial. Archives of Internal Medicine 1990;150:1677-82. Ref ID: 11 17. Weyand CM,.Goronzy JJ. Immune responses to Borrelia burgdorferi in patients with reactive arthritis. Arthritis & Rheumatism 1989;32:1057-64. Ref ID: 12 18. Steere AC, Bartenhagen NH, Craft JE, Hutchinson GJ, Newman JH, Pachner et al. Clinical manifestations of Lyme disease. [Review] [41 refs]. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene - Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology 1986;263:201-5. Ref ID: 13 19. Treib J, Fernandez A, Haass A, Grauer MT, Holzer G, Woessner R. Clinical and serologic follow-up in patients with neuroborreliosis [see comments]. Neurology 1998;51:1489-91. Ref ID: 14 20. Akin E, McHugh GL, Flavell RA, Fikrig E, Steere AC. The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis. Infection & Immunity 1999;67:173-81. Ref ID: 15 21. Karma A, Stenborg T, Summanen P, Immonen I, Mikkila H, Seppala I. Long-term follow-up of chronic Lyme neuroretinitis. Retina 1996;16:505-9. Ref ID: 16 22. Kaiser R. Variable CSF findings in early and late Lyme neuroborreliosis: a follow-up study in 47 patients. Journal of Neurology 1994;242:26-36. Ref ID: 17 23. Hammers-Berggren S, Lebech AM, Karlsson M, Andersson U, Hansen K, Stiernstedt G. Serological follow-up after treatment of Borrelia arthritis and acrodermatitis chronica atrophicans. Scandinavian Journal of Infectious Diseases 1994;26:339-47. Ref ID: 18 24. Asch ES, Bujak DI, Weiss M, Peterson MG, Weinstein A. Lyme disease: an infectious and postinfectious syndrome. [Review] [37 refs]. Journal of Rheumatology 1994;21 :454-61. Ref ID: 19 25. Szer IS, Taylor E, Steere AC. The long-term course of Lyme arthritis in children [see comments]. New England Journal of Medicine 1991;325:159-63. RefID:20 212 26. Kruger H, Pulz M, Martin R, Sticht-Groh V. Long-term persistence of specific T- and B-lymphocyte responses to Borrelia burgdorferi following untreated neuroborreliosis. Infection 1990;18:263-7. Ref ID: 21 27. Kruger H, Reuss K, Pulz M, Rohrbach E, Pflughaupt KW, Martin R et al. Meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a follow-up study of 72 patients over 27 years. Journal of Neurology 1989;236:322-8. Ref ID: 22 28. Gerber MA, Shapiro ED, Burke GS, Parcells VJ, Bell GL. Lyme disease in children in southeastern Connecticut. Pediatric Lyme Disease Study Group [see comments]. New England Journal of Medicine 1996;335:1270-4. Ref ID: 24 29. Kuiper H, de Jongh BM, van Dam AP, Dodge DE, RaMSelaar AC, Spanjaard L et al. Evaluation of central nervous system involvement in Lyme borreliosis patients with a solitary erythema migrans lesion. European Journal of Clinical Microbiology & Infectious Diseases 1994;13:379-87. 30. Ref ID: 25 31. Hansen K,.Lebech AM. The clinical and epidemiological profile of Lyme neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain 1992;115:399-423. Ref ID: 26 32. Belani K,.Regelmann WE. Lyme disease in children. [Review] [39 refs]. Rheumatic Diseases Clinics of North America 1989;15:679-90. Ref ID: 27 32. Treib J, Fernandez A, Haass A, Grauer MT, Holzer G, Woessner R. Clinical and serologic follow-up in patients with neuroborreliosis [see comments]. Neurology 1998;51:1489-91. Ref ID: 28 33. Phillips SE, Mattman LH, Hulinska D, Moayad H. A proposal for the reliable culture of Borrelia burgdorferi from patients with chronic Lyme disease, even from those previously aggressively treated. Infection 1998;26:364-7. Ref ID: 29 34. Oschmann P, Dorndorf W, Hornig C, Schafer C, Wellensiek HJ, Pflughaupt et al. Stages and syndromes of neuroborreliosis. Journal of Neurology 1998;245:262-72. Ref ID: 30 34. MacDonald KL, Osterholm MT, LeDell KH, White KE, Schenck CH, Chao CC et al. A case-control study to assess possible triggers and cofactors in chronic fatigue syndrome [see comments]. American Journal of Medicine 1996;100:548-54. Ref ID: 31 35. Mawle AC, Nisenbaum R, Dobbins JG, Gary HE, Jr., Stewart JA, Reyes M et al. Seroepidemiology of chronic fatigue syndrome: a case-control study. Clinical Infectious Diseases 1995;21:1386-9. Ref ID: 32 213 36. Buechner SA, Lautenschlager S, Itin P, Bircher A, Erb P. Lymphoproliferative responses to Borrelia burgdorferi in patients with erythema migrans, acrodermatitis chronica atrophicans, lymphadenosis benigna cutis, and morphea. Archives of Dermatology 1995;131:673-7. Ref ID: 33 37. Duray PH. Clinical pathologic correlations of Lyme disease. Reviews of Infectious Diseases 1989;11 Suppl 6:S1487-S1493. Ref ID: 34 39. Seltzer, E.G, Gerber, M.A.,Cartter M.L., Freudigman K and Shapiro E.D. (2000) Long term outcomes of persons with Lyme Disease. JAMA 283(5): 609-616. 40. Sigal LH. Musculoskeletal manifestations of Lyme arthritis. [Review] [141 refs]. Rheumatic Diseases Clinics of North America 1998;24:323-51. Ref ID: 14 41. Eustace SJ, Lan HH, Dorfman D. Lyme arthropathy. [Review] [22 refs]. Radiologic Clinics of North America 1996;34:454-5. Ref ID: 35 42. Burmester GR, Daser A, Kamradt T, Krause A, Mitchison NA, Sieper J et al. Immunology of reactive arthritides. [Review] [161 refs]. Annual Review of Immunology 1995;13:229-50. Ref ID: 43 43. Ilowite NT. Muscle, reticuloendothelial, and late skin manifestations of Lyme disease. [Review] [44 refs]. American Journal of Medicine 1995;98:63S-8S. Ref ID: 45 44. Steere AC. Musculoskeletal manifestations of Lyme disease. [Review] [36 refs]. American Journal of Medicine 1995;98:44S-8S. Ref ID: 46 45. Dressler F. Infectious diseases affecting the musculoskeletal system in children and adolescents. [Review] [69 refs]. Current Opinion in Rheumatology 1993;5:651-7. Ref ID: 63 46. Burmester GR. Lessons from Lyme arthritis. [Review] [25 refs]. Clinical & Experimental Rheumatology 1993;11 Suppl 8:S23-S27. Ref ID: 66 47. Lawrence SJ. Lyme disease: an orthopedic perspective [see comments]. [Review] [29 refs]. Orthopedics (Thorofare, NJ) 1992;15:1331-5. Ref ID: 70 48. Coovadia HM. Rheumatic fever and disorders of the musculoskeletal system. [Review] [35 refs]. Current Opinion in Rheumatology 1992;4:718-24. Ref ID: 71 49. Scerpella TA,.Engber WD. Chronic Lyme disease arthritis: review of the literature and report of a case of wrist arthritis. [Review] [23 refs]. Journal of Hand Surgery - American Volume 1992;17:571-5. Ref ID: 73 214 50. Steere AC. Clinical definitions and differential diagnosis of Lyme arthritis. [Review] [8 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1991;77:51-4. Ref ID: 77 51. Kahan A, Amor B, Menkes CJ. Lyme arthritis. [Review] [19 refs]. Biomedicine & Pharmacotherapy 1989;43:401-3. Ref ID: 99 52. Kolstoe J,.Messner RP. Lyme disease: musculoskeletal manifestations. [Review] [32 refs]. Rheumatic Diseases Clinics of North America 1989;15:649-56. Ref ID: 100 53. Wilke M, Eiffert H, Christen HJ, Hanefeld F. Primarily chronic and cerebrovascular course of Lyme neuroborreliosis: case reports and literature review. [Review] [35 refs]. Archives of Disease in Childhood 2000;83:67-71. Ref ID: 3 54. Kaiser R. Neuroborreliosis. [Review] [111 refs]. Journal of Neurology 1998; 245:247-55. Ref ID: 15 55. Kaplan RF,.Jones-Woodward L. Lyme encephalopathy: a neuropsychological perspective. [Review] [42 refs]. Seminars in Neurology 1997;17:31-7. Ref ID: 23 56. Logigian EL. Peripheral nervous system Lyme borreliosis. [Review] [0 refs]. Seminars in Neurology 1997;17:25-30. Ref ID: 24 57. Kristoferitsch W. Neurologic manifestations in Lyme borreliosis. [Review] [103 refs]. Clinics in Dermatology 1993;11:393-400. Ref ID: 61 58. Kristoferitsch W. Neurological manifestations of Lyme borreliosis: clinical definition and differential diagnosis. [Review] [88 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1991;77:64-73. Ref ID: 78 59. Halperin JJ. North American Lyme neuroborreliosis. [Review] [31 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1991;77:74-80. Ref ID: 81 60. Kristoferitsch W. Neurological manifestations of Lyme borreliosis [published erratum appears in Infection 1991 Sep-Oct;19(5):350]. [Review] [61 refs]. Infection 1991;19:268-72. Ref ID: 82 60. Halperin JJ. Nervous system manifestations of Lyme disease. [Review] [52 refs]. Rheumatic Diseases Clinics of North America 1989;15:635-47. Ref ID: 96 61. Pachner AR. Lyme disease. [Review] [40 refs]. Trends in Neurosciences 1989;12:177-81. Ref ID: 108 62. Mertens HG, Martin R, Kohlhepp W. Clinical and neuroimmunological findings in chronic Borrelia burgdorferi radiculomyelitis (Lyme disease). [Review] [32 refs]. Journal of Neuroimmunology 1988;20:309-14. Ref ID: 115 63. Ilowite NT. Muscle, reticuloendothelial, and late skin manifestations of Lyme disease. [Review] [44 refs]. American Journal of Medicine 1995;98:63S-8S. Ref ID: 45 215 64. Khorenian SD,.Lebwohl M. New cutaneous manifestations of systemic diseases [see comments]. [Review] [18 refs]. American Family Physician 1995;51:625-30. Ref ID: 50 65. DiCaudo DJ, Su WP, Marshall WF, Malawista SE, Barthold S, Persing DH. Acrodermatitis chronica atrophicans in the United States: clinical and histopathologic features of six cases. [Review] [18 refs]. Cutis 1994;54:81-4. Ref ID: 51 66. Asbrink E. Acrodermatitis chronica atrophicans. [Review] [44 refs]. Clinics in Dermatology 1993;11:369-75. Ref ID: 62 67. Asbrink E. Cutaneous manifestations of Lyme borreliosis. Clinical definitions and differential diagnoses. [Review] [31 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1991;77:44-50. Ref ID: 76 68. Asbrink E,.Hovmark A. Lyme borreliosis: aspects of tick-borne Borrelia burgdorferi infection from a dermatologic viewpoint. [Review] [120 refs]. Seminars in Dermatology 1990;9:277-91. Ref ID: 87 69. Leys AM, Schonherr U, Lang GE, Naumann GO, Goubau P, Honore A et al. Retinal vasculitis in Lyme borreliosis. [Review] [64 refs]. Bulletin de la Societe Belge d Ophtalmologie 1995;259:205-14. Ref ID: 36 70. Sigal LH. Early disseminated Lyme disease: cardiac manifestations. [Review] [32 refs]. American Journal of Medicine 1995;98:25S-8S. Ref ID: 48 71. Cox J,.Krajden M. Cardiovascular manifestations of Lyme disease. [Review] [102 refs]. American Heart Journal 1991;122:1449-55. Ref ID: 79 72. Hu LT,.Klempner MS. Host-pathogen interactions in the immunopathogenesis of Lyme disease. [Review] [136 refs]. Journal of Clinical Immunology 1997;17:354-65. Ref ID: 20 73. Aberer E, Koszik F, Silberer M. Why is chronic Lyme borreliosis chronic?. [Review] [61 refs]. Clinical Infectious Diseases 1997;25 Suppl 1:S64-S70. Ref ID: 21 74. England JD, Bohm RP, Jr., Roberts ED, Philipp MT. Lyme neuroborreliosis in the rhesus monkey. [Review] [32 refs]. Seminars in Neurology 1997;17:53-6. Ref ID: 22 75. Garcia-Monco JC,.Benach JL. Mechanisms of injury in Lyme neuroborreliosis. [Review] [90 refs]. Seminars in Neurology 1997;17:57-62. Ref ID: 25 216 76. Sigal LH. Persisting complaints attributed to chronic Lyme disease: possible mechanisms and implications for management [see comments]. [Review] [116 refs]. American Journal of Medicine 1994;96:365-74. Ref ID: 59 77. Benach JL, Fernandez VB, Szczepanski A, Garcia MJ. Lyme borreliosis: non-specific interactions of the organism with the host. [Review] [35 refs]. Scandinavian Journal of Infectious Diseases - Supplementum 1991;77:130-5. Ref ID: 74 78. Melski JW. Lyme borreliosis. [Review] [80 refs]. Seminars in Cutaneous Medicine & Surgery 2000;19:10-8. Ref ID: 1 79. Evans J. Lyme disease. [Review] [62 refs]. Current Opinion in Rheumatology 1999;11:281-8. 80. Fredricks DN,.Relman DA. Infectious agents and the etiology of chronic idiopathic diseases. [Review] [90 refs]. Current Clinical Topics in Infectious Diseases 1998;18:180-200. Ref ID: 11 81. Berger BW. Current aspects of Lyme disease and other Borrelia burgdorferi infections. [Review] [58 refs]. Dermatologic Clinics 1997;15:247-55. Ref ID: 26 82. Ellenbogen C. Lyme disease. Shift the paradigm:. [Review] [35 refs]. Archives of Family Medicine 1997;6:191-5. Ref ID: 27 83. Sigal LH. Persisting symptoms of Lyme disease--possible explanations and implications for treatment [editorial]. [Review] [23 refs]. Journal of Rheumatology 1994;21 :593-5. Ref ID: 55 84. Asch ES, Bujak DI, Weiss M, Peterson MG, Weinstein A. Lyme disease: an infectious and postinfectious syndrome. [Review] [37 refs]. Journal of Rheumatology 1994;21 :454-61. Ref ID: 57 86 Abele DC,.Anders KH. The many faces and phases of borreliosis. I. Lyme disease [published erratum appears in J Am Acad Dermatol 1991 Apr;24(4):663] [see comments]. [Review] [293 refs]. Journal of the American Academy of Dermatology 1990;23:167-86. Ref ID: 88 87 Abele DC,.Anders KH. The many faces and phases of borreliosis II. [Review] [112 refs]. Journal of the American Academy of Dermatology 1990;23:401-10. Ref ID: 89 88. Duffy J. Lyme disease. [Review] [140 refs]. Annals of Allergy 1990;65:1-13. Ref ID: 90 89. Tortorice KL,.Heim-Duthoy KL. Clinical features and treatment of Lyme disease. [Review] [64 refs]. Pharmacotherapy 1989;9:363-71. Ref ID: 95 217 90. Garcia-Monco JC,.Benach JL. The pathogenesis of Lyme disease. [Review] [87 refs]. Rheumatic Diseases Clinics of North America 1989;15:711-26. Ref ID: 97 91. Belani K,.Regelmann WE. Lyme disease in children. [Review] [39 refs]. Rheumatic Diseases Clinics of North America 1989;15:679-90. Ref ID: 101 92. Luft BJ,.Dattwyler RJ. Lyme borreliosis. [Review] [205 refs]. Current Clinical Topics in Infectious Diseases 1989;10:56-81. Ref ID: 105 93. Steere AC. Lyme disease [see comments]. [Review] [162 refs]. New England Journal of Medicine 1989;321:586-96. Ref ID: 107 94. Saag MS,.Bennett JC. The infectious etiology of chronic rheumatic diseases. [Review] [187 refs]. Seminars in Arthritis & Rheumatism 1987;17:1-23. Ref ID: 117 95. Steere AC, Bartenhagen NH, Craft JE, Hutchinson GJ, Newman JH, Pachner et al. Clinical manifestations of Lyme disease. [Review] [41 refs]. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene - Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology 1986;263:201-5. Ref ID: 119 Borrelia and Chronic Health Effects - science citation index search 1 Abarca K, Ribera M, Prado P, Lobos T, Palacios O, Ferres M et al. Lyme Borreliosis in Chile. Report of a child probably infected by imported pets. Revista Medica De Chile 1996;124:975-9. 2 Aberer E, Kehldorfer M, Binder B, Schauperl H. The outcome of Lyme borreliosis in children. Wiener Klinische Wochenschrift 1999;111:941-4. 3 Adams WV, Rose CD, Eppes SC, Klein JD. cognitive effects of lyme-disease in children. Pediatrics 1994;94:185-9. 4 Altpeter ES,.Meier C. Lyme borreliosis in switzerland - epidemiologic aspects of neurologic complications. Schweizerische Medizinische Wochenschrift 1992;122:22-6. 5 Ananjeva LP, Skripnikova IA, Barskova VG, Steere AC. Clinical and serologic features of lyme borreliosis in Russia. Journal Of Rheumatology 1995;22:689-94. 6 Ananyeva LP, Skripnikova IA, Barskova VG, Stir AS. Clinical and serological manifestations of Lyme's disease in Russia. Terapevticheskii Arkhiv 1995;67:38-42. 7 Anda P, Rodriguez I, Delaloma A, Fernandez MV, Lozano A. A serological survey and review of clinical Lyme borreliosis in Spain. Clinical Infectious Diseases 1993;16:310-9. 8 Attane F, Henry S, Clave D, Massip P, Tannier C, Arzouni JP et al. Neuroborreliosis: Clinical features and diagnosis in an atypical case. Semaine Des Hopitaux 1996;72:784-7. 218 9 Badalyan LO, Kravchuk LN, Sergovskaya VD, Belousova VS, Minina AP. Neurological syndromes in children with Lyme-disease. Zhurnal Nevropatologii I Psikhiatrii Imeni S S Korsakova 1994;94:3-6. 10 Balcer LJ, Winterkorn JMS, Galetta SL. Neuro-ophthalmic manifestations of Lyme disease. Journal Of Neuro-Ophthalmology 1997;17:108-21. 11 Belaich S. Lyme-disease. Presse Medicale 1995;24:81-&. 12 Berglund J,.Eitrem R. Tick-borne borreliosis in the archipelago of Southern Sweden. Scandinavian Journal Of Infectious Diseases 1993;25:67-72. 13 Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringner A, Elmrud H et al. An epidemiologic-study of lyme-disease in southern Sweden. New England Journal Of Medicine 1995;333:1319-24. 14 Berglund J, Hansen BU, Eitrem R. Lyme arthritis - a common manifestation in a highly endemic area in Sweden. Journal Of Rheumatology 1995;22:695-701. 15 Bingham PM, Galetta SL, Athreya B, Sladky J. Neurologic manifestations in children with Lyme-disease. Pediatrics 1995;96:1053-6. 16 Bujak DI, Weinstein A, Dornbush RL. Clinical and neurocognitive features of the post Lyme syndrome. Journal Of Rheumatology 1996;23:1392-7. 17 Christen HJ, Hanefeld F, Eiffert H, Thomssen R. Epidemiology and clinical manifestations of Lyme borreliosis in childhood - a prospective multicenter study with special regard to neuroborreliosis. Acta Paediatrica 1993;82:1-76. 18 Christmann D, Hansmann Y, Erhart A, Warter JM, Jaulhac B. Neurologic manifestations in Lyme borreliosis. Medecine Et Maladies Infectieuses 1998;28:354-8. 19 Curless RG, Schatz NJ, Bowen BC, Rodriguez Z, Ruiz A. Lyme neuroborreliosis masquerading as a brainstem tumor in a 15-year-old. Pediatric Neurology 1996;15:258-60. 20 Dekonenko EP, Umansky KG, Virich IE, Kupriyanova LV, Rudometov YP, Bagrov FI. Leading neurological syndromes in Lyme-Borreliosis. Terapevticheskii Arkhiv 1995;67:52-3. 21 Deltombe T, Hanson P, Boutsen Y, Laloux P, Clerin M. Lyme borreliosis neuropathy - A case report. American Journal Of Physical Medicine & Rehabilitation 1996;75:314-6. 22 Fallon BA, Nields JA, Parsons B, Liebowitz MR, Klein DF. Psychiatric manifestations of lyme borreliosis. Journal Of Clinical Psychiatry 1993;54:263-8. 23 Fallon BA,.Nields JA. Lyme-disease - a neuropsychiatric illness. American Journal Of Psychiatry 1994;151:1571-83. 24 Faul JL, Ruoss S, Doyle RL, Kao PN. Diaphragmatic paralysis due to Lyme disease. European Respiratory Journal 1999;13:700-2. 25 GarciaMonco JC,.Benach JL. Lyme neuroborreliosis. Annals Of Neurology 1995;37:691-702. 219 27 Grau AJ, Buggle F, Hacke W. Infectious diseases as cause and as risk factor of cerebrovascular ischemia. Nervenarzt 1996;67:639-49. 28 Haass A,.Treib J. Neurologic manifestation and classification of borreliosis. Infection 1996;24:467-9. 30 Halperin JJ. Neuroborreliosis. American Journal Of Medicine 1995;98:S52-S59. 31 Halperin JJ. Neuroborreliosis: Central nervous system involvement. Seminars In Neurology 1997;17:19-24. 32 Halperin JJ. Nervous system Lyme disease. Infections In Medicine 2000;17:556-60. 33 Herzer P. Joint manifestations of lyme-borreliosis in Europe. Scandinavian Journal Of Infectious Diseases 1991;55-63. 37 Kolmel HW, Neumann P, Lange R. Prevalence of Borrelia-burgdorferi antibodies in 800 neurological patients. Nervenarzt 1992;63:619-24. 39 Krupp LB, Masur D, Schwartz J, Coyle PK, Langenbach LJ, Fernquist SK et al. Cognitive-functioning in late Lyme borreliosis. Archives Of Neurology 1991;48:1125-9. 40 Laroche C, Lienhardt A, Boulesteix J. Ischemic stroke due to neuroborreliosis. Archives De Pediatrie 1999;6:1302-5. 41 Lawrence C, Lipton RB, Lowy FD, Coyle PK. Seronegative chronic relapsing neuroborreliosis. European Neurology 1995;35:113-7. 42 Logigian EL. Chronic lyme neuroborreliosis. Terapevticheskii Arkhiv 1996;68:41-4. 43 Marguet C, Rouillier-Saas M, Mallet E, Meunier M, Jeannot E, Boulloche J et al. Lyme disease in upper Normandy: a hospital survey. Archives De Pediatrie 2000;7:517S-22S. 44 Mourin S, Bonnier C, Bigaignon G, Lyon G. Neuroborreliosis revealed by epilepsy. Revue Neurologique 1993;149:489-91. 45 Muller M, Retzl J, Plank E, Scholz H, Ziervogel H, Stanek G. Prevalence of Borrelia burgdorferi serum antibodies in 651 patients suffering predominantly from neurological complaints. Wiener Klinische Wochenschrift 1993;105:599-602. 46 Murray R, Morawetz R, Kepes J, Elgammal T, Ledoux M. Lyme neuroborreliosis manifesting as an intracranial mass lesion. Neurosurgery 1992;30:769-73. 47 Niemann G, Koksal MA, Oberle A, Michaelis R. Facial palsy and Lyme borreliosis: Long-term follow-up of children with antibiotically untreated ''idiopathic'' facial palsy. Klinische Padiatrie 1997;209:95-9. 48 Oksi J, Kalimo H, Marttila RJ, Marjamaki M, Sonninen P, Nikoskelainen J et al. Inflammatory brain changes in Lyme borreliosis - A report on three patients and review of literature. Brain 1996;119:2143-54. 49 Picha D, Doutlik S, Moravcova L. Nervous manifestations of Lyme borreliosis. Ceska A Slovenska Neurologie A Neurochirurgie 1996;59:308-13. 50 Prasad A,.Younger DS. Lyme neuroborreliosis. Drugs Of Today 1998;34:537-40. 220 51 Ragnaud JM, Morlat P, Ferrer X, Orgogozo JM, Julien J, Beylot J et al. Neurological symptoms of Lyme-disease - review of 22 cases. Revue De Medecine Interne 1993;14:985-. 52 Ragnaud JM, Morlat P, Buisson M, Ferrer X, Orgogozo JM, Julien J et al. Neurological features of Lyme-disease in 25 cases. Revue De Medecine Interne 1995;16:48794. 53 Reik L. Stroke due to Lyme-disease. Neurology 1993;43:2705-7. 54 Roberg M, Forsberg P, Fryden A, Hederstedt B, Hyden D, Odkvist L. Long-term findings in patients with facial palsy and antibodies against Borrelia burgdorferi. Scandinavian Journal Of Infectious Diseases 1994;26:559-67. 55 Shadick NA, Phillips CB, Logigian EL, Steere AC, Kaplan RF, Berardi VP et al. The long-term clinical outcomes of Lyme-disease - a population- based retrospective cohort study. Annals Of Internal Medicine 1994;121:560-&. 56 Shapiro ED,.Seltzer EG. Lyme disease in children. Seminars In Neurology 1997;17:39-44. 57 Silva MT, Sophar M, Howard RS, Spencer GT. Neuroborreliosis as a cause of respiratory-failure. Journal Of Neurology 1995;242:604-7. 58 Soumare M, Diop BM, Ndour CT, Dieng Y, Badiane S. Epidemiological aspects of borreliosis in a hospital setting in Dakar, Senegal. Medecine Et Maladies Infectieuses 1999;29:191-4. 59 StilleSiegener M, Eiffert H, Vonhof S. Cardiac and neurological manifestations of borreliosis (Lyme disease) in a patient with 1 degrees AV block. Deutsche Medizinische Wochenschrift 1996;121:1292-6. 60 Svengusson B,.Lindh G. Lyme borreliosis - An overdiagnosed disease? Infection 1997;25:140-3. 61 Swenson RS. Occipital neuralgia from Lyme disease. Journal Of The Neuromusculoskeletal System 1997;5:95-101. 62 Ushakova MA, Ananyeva LP, Mach ES, Pushkova OV, Barskova VG, Skripnikova IA. Locomotor defects secondary to Lyme's disease: Clinical and instrumental characteristics. Terapevticheskii Arkhiv 1995;67:45-9. 63 Wobrock T, Weidauer S, Firnhaber W. Borreliosis encephalitis presenting with tension headache. Aktuelle Neurologie 1996;23:125-6. 64 Zamponi N, Cardinali C, Tavoni MA, Porfiri L, Rossi R, Manca A. Chronic neuroborreliosis in infancy. Italian Journal Of Neurological Sciences 1999;20:303-7. 221 BARTONELLA Occupational relevance 1. Kelly PJ, Matthewman LA, Hayter D, Downey S, Wray K, Bryson NR et al. Bartonella (Rochalimaea) henselae in southern Africa--evidence for infections in domestic cats and implications for veterinarians. Journal of the South African Veterinary Association 1996;67:182-7. Ref ID: 135 2. Noah DL, Kramer CM, Verbsky MP, Rooney JA, Smith KA, Childs JE. Survey of veterinary professionals and other veterinary conference attendees for antibodies to Bartonella henselae and B quintana. Journal of the American Veterinary Medical Association 1997;210:342-4. Ref ID: 154 3. Welch DF, Carroll KC, Hofmeister EK, Persing DH, Robison DA, Steigerwalt et al. Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice. Journal of Clinical Microbiology 1999;37:2598-601. Ref ID: 682 BARTONELLA AND SEVERAL CHRONIC EFFECTS Bartonella and Chronic Disease – medline search 1. Maguina C,.Gotuzzo E. Bartonellosis. New and old. [Review] [94 refs]. Infectious Disease Clinics of North America 0 AD/3/20;14:1-22. Ref ID: 8 2. Dehio C. Interactions of Bartonella henselae with vascular endothelial cells. [Review] [36 refs]. Current Opinion in Microbiology 1999;2:78-82. Ref ID: 29 3. Loutit JS. Bartonella infections: diverse and elusive. Hospital Practice (Office Edition) 1941;33:37-8. Ref ID: 43 4. Spach DH,.Koehler JE. Bartonella-associated infections. [Review] [104 refs]. Infectious Disease Clinics of North America 1998;12:137-55. Ref ID: 55 5. Maurin M, Birtles R, Raoult D. Current knowledge of Bartonella species. [Review] [159 refs]. European Journal of Clinical Microbiology & Infectious Diseases 1997;16:487 506. Ref ID: 62 6. Maurin M,.Raoult D. Bartonella (Rochalimaea) quintana infections. [Review] [170 refs]. Clinical Microbiology Reviews 1996;9:273-92. 7. Koehler JE. Bartonella infections. [Review] [67 refs]. Advances in Pediatric Infectious Diseases 1996;11:1-27. Ref ID: 81 222 8. Marra CM. Neurologic complications of Bartonella henselae infection. [Review] [65 refs]. Current Opinion in Neurology 1995;8:164-9. 9. Batsakis JG, Ro JY, Frauenhoffer EE. Bacillary angiomatosis. [Review] [10 refs]. Annals of Otology, Rhinology & Laryngology 1995;104:668-72. Ref ID: 95 10. Spach DH, Kanter AS, Daniels NA, Nowowiejski DJ, Larson AM, Schmidt RA et al. Bartonella (Rochalimaea) species as a cause of apparent "culture-negative" endocarditis. [Review] [19 refs]. Clinical Infectious Diseases 1995;20:1044-7. Ref ID: 96 11. Maeno N, Oda H, Yoshiie K, Wahid MR, Fujimura T, Matayoshi S. Live Bartonella henselae enhances endothelial cell proliferation without direct contact. Microbial Pathogenesis 1999;27:419-27. Ref ID: 12 12. Burgess AW,.Anderson BE. Outer membrane proteins of Bartonella henselae and their interaction with human endothelial cells. Microbial Pathogenesis 1998;25:157-64. Ref ID: 44 13. Borczuk AC, Niedt G, Sablay LB, Kress Y, Mannion CM, Factor SM et al. Fibrous long-spacing collagen in bacillary angiomatosis [see comments]. Ultrastructural Pathology 1998;22:127-33. Ref ID: 50 14. Iwaki-Egawa S,.Ihler GM. Comparison of the abilities of proteins from Bartonella bacilliformis and Bartonella henselae to deform red cell membranes and to bind to red cell ghost proteins. FEMS Microbiology Letters 1997;157:207-17. 15. Dehio C, Meyer M, Berger J, Schwarz H, Lanz C. Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome. Journal of Cell Science 1997;110:2141-54. Ref ID: 61 16. Maurin M, Eb F, Etienne J, Raoult D. Serological cross-reactions between Bartonella and Chlamydia species: implications for diagnosis. Journal of Clinical Microbiology 1997;35:2283-7. Ref ID: 64 17. Brouqui P,.Raoult D. Bartonella quintana invades and multiplies within endothelial cells in vitro and in vivo and forms intracellular blebs. Research in Microbiology 1996;147:719-31. Ref ID: 71 18. Palmari J, Teysseire N, Dussert C, Raoult D. Image cytometry and topographical analysis of proliferation of endothelial cells in vitro during Bartonella (Rochalimaea) infection. Analytical Cellular Pathology 1996;11:13-30. Ref ID: 73 19. La Scola B,.Raoult D. Serological cross-reactions between Bartonella quintana, Bartonella henselae, and Coxiella burnetii. Journal of Clinical Microbiology 1996;34:2270-4. Ref ID: 74 223 20. Conley T, Slater L, Hamilton K. Rochalimaea species stimulate human endothelial cell proliferation and migration in vitro [see comments]. Journal of Laboratory & Clinical Medicine 1994;124:521-8. Ref ID: 104 21. Garcia FU, Wojta J, Hoover RL. Interactions between live Bartonella bacilliformis and endothelial cells. Journal of Infectious Diseases 1992;165:1138-41. Ref ID: 105 22. Garcia FU, Wojta J, Broadley KN, Davidson JM, Hoover RL. Bartonella bacilliformis stimulates endothelial cells in vitro and is angiogenic in vivo. American Journal of Pathology 1990;136:1125-35. Ref ID: 106 23. Harrison TG,.Doshi N. Serological evidence of Bartonella spp. infection in the UK. Epidemiology & Infection 1999;123:233-40. Ref ID: 18 24. La Scola B,.Raoult D. Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). Journal of Clinical Microbiology 1999;37:1899-905. Ref ID: 28 25. Brouqui P, Lascola B, Roux V, Raoult D. Chronic Bartonella quintana bacteremia in homeless patients. New England Journal of Medicine 1999;340:184-9. Ref ID: 35 26. Raoult D, Fournier PE, Drancourt M, Marrie TJ, Etienne J, Cosserat J et al. Diagnosis of 22 new cases of Bartonella endocarditis [published erratum appears in Ann Intern Med 1997 Aug 1;127(3):249]. Annals of Internal Medicine 1996;125:646-52. Ref ID: 80 27. Simon-Vermont I, Altwegg M, Zimmerli W, Fluckiger U. Duke criteria-negative endocarditis caused by Bartonella quintana. Infection 1999;27:283-5. Ref ID: 4 28. Barbe KP, Jaeggi E, Ninet B, Liassine N, Donatiello C, Gervaix A et al. Bartonella quintana endocarditis in a child [letter]. New England Journal of Medicine 2000;342:1841-2. Ref ID: 7 29. Roux V, Eykyn SJ, Wyllie S, Raoult D. Bartonella vinsonii subsp. berkhoffii as an agent of afebrile blood culture-negative endocarditis in a human. Journal of Clinical Microbiology 2000;38:1698-700. Ref ID: 10 30. James EA, Hill J, Uppal R, Prentice MB. Bartonella infection: a significant cause of native valve endocarditis necessitating surgical management. Journal of Thoracic & Cardiovascular Surgery 2000;119:171-2. Ref ID: 13 31. Patel R, Newell JO, Procop GW, Persing DH. Use of polymerase chain reaction for citrate synthase gene to diagnose Bartonella quintana endocarditis. American Journal of Clinical Pathology 1999;112:36-40. Ref ID: 23 224 32. Guyot A, Bakhai A, Fry N, Merritt J, Malnick H, Harrison T. Culture-positive Bartonella quintana endocarditis. European Journal of Clinical Microbiology & Infectious diseases 1999;18:145-7. Ref ID: 25 33. Heller R, Riegel P, Hansmann Y, Delacour G, Bermond D, Dehio C et al. Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. International Journal of Systematic Bacteriology 1998;48 Pt 4 :1333-9. Ref ID: 39 34. Bruneel F, D'estanque J, Fournier PE, Arlet G, Thuong M, Wolff M et al. Isolated right-sided Bartonella quintana endocarditis in an immunocompetent adult. Scandinavian Journal of Infectious Diseases 1998;30:424-5. Ref ID: 42 35. Pollock SC,.Kristinsson J. Cat-scratch disease manifesting as unifocal helioid choroiditis [letter]. Archives of Ophthalmology 1998;116:1249-51. Ref ID: 48 6. Baorto E, Payne RM, Slater LN, Lopez F, Relman DA, Min KW et al. Culture negative endocarditis caused by Bartonella henselae. Journal of Pediatrics 1998;132:1051-4. Ref ID: 53 38. Breathnach AS, Hoare JM, Eykyn SJ. Culture-negative endocarditis: contribution of bartonella infections. Heart 1997;77:474-6. Ref ID: 66 37. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 2-1997. A 38-year-old man with digital clubbing, low-grade fever, and a murmur [clinical conference]. New England Journal of Medicine 1997;336:205-10. Ref ID: 69 38. Smith KJ, Skelton HG, Tuur S, Larson PL, Angritt P. Bacillary angiomatosis in an immunocompetent child. American Journal of Dermatopathology 1996;18:597-600. Ref ID: 72 39. Drancourt M, Birtles R, Chaumentin G, Vandenesch F, Etienne J, Raoult D. New serotype of Bartonella henselae in endocarditis and cat-scratch disease [published erratum appears in Lancet 1996 Mar 23;347(9004):842]. Lancet 1996;347:441-3. Ref ID: 86 41 Newsom RW, Martin TJ, Wasilauskas B. Cat-scratch disease diagnosed serologically using an enzyme immunoassay in a patient with neuroretinitis [letter]. Archives of Ophthalmology 1996;114:493-4. Ref ID: 87 42. Jalava J, Kotilainen P, Nikkari S, Skurnik M, Vanttinen E, Lehtonen OP et al. Use of the polymerase chain reaction and DNA sequencing for detection of Bartonella quintana in the aortic valve of a patient with culture-negative infective endocarditis. Clinical Infectious Diseases 1995;21:891-6. Ref ID: 88 225 43. Holmes AH, Greenough TC, Balady GJ, Regnery RL, Anderson BE, O'Keane JC et al. Bartonella henselae endocarditis in an immunocompetent adult. Clinical Infectious Diseases 1995;21:1004-7. Ref ID: 89 43. Spach DH, Kanter AS, Dougherty MJ, Larson AM, Coyle MB, Brenner DJ et al. Bartonella (Rochalimaea) quintana bacteremia in inner-city patients with chronic alcoholism see comments]. New England Journal of Medicine 1995;332:424-8. Ref ID: 99 44. Drancourt M, Mainardi JL, Brouqui P, Vandenesch F, Carta A, Lehnert F et al. Bartonella (Rochalimaea) quintana endocarditis in three homeless men [see comments]. New England Journal of Medicine 1995;332:419-23. Ref ID: 100 45. Solley WA, Martin DF, Newman NJ, King R, Callanan DG, Zacchei T et al. Cat scratch disease: posterior segment manifestations [see comments]. Ophthalmology 1999;106:1546-53. Ref ID: 5 46. Eggenberger E. Cat scratch disease: posterior segment manifestations [letter; comment]. Ophthalmology 2000;107:817-8. Ref ID: 6 47. Kerkhoff FT, Bergmans AM, van Der ZA, Rothova A. Demonstration of Bartonella grahamii DNA in ocular fluids of a patient with neuroretinitis. Journal of Clinical Microbiology 1999;37:4034-8. Ref ID: 16 48. Lombardo J. Cat-scratch neuroretinitis. Journal of the American Optometric Association 1999;70:525-30. Ref ID: 20 49. Wade NK, Po S, Wong IG, Cunningham ET, Jr. Bilateral Bartonella-associated neuroretinitis. Retina 1999;19:355-6. Ref ID: 21 50. Rosen BS, Barry CJ, Nicoll AM, Constable IJ. Conservative management of documented neuroretinitis in cat scratch disease associated with Bartonella henselae infection. Australian & New Zealand Journal of Ophthalmology 1999;27:153-6. Ref ID: 24 51. Kerkhoff FT, Ossewaarde JM, de Loos WS, Rothova A. Presumed ocular bartonellosis. British Journal of Ophthalmology 1999;83:270-5. Ref ID: 26 52. Gray AV, Reed JB, Wendel RT, Morse LS. Bartonella henselae infection associated with peripapillary angioma, branch retinal artery occlusion, and severe vision loss. American Journal of Ophthalmology 1999;127:223-4. Ref ID: 31 53. Rosen B. Management of B. henselae neuroretinitis in cat-scratch disease [letter; comment]. Ophthalmology 1999;106:1-2. Ref ID: 33 226 54. Lee AG. Cat-scratch disease [letter; comment]. Ophthalmology 1999;106:1. Ref ID: 34 55. Ghauri RR,.Lee AG. Optic disk edema with a macular star. Survey of Ophthalmology 1998;43:270-4. Ref ID: 38 56. Rothova A, Kerkhoff F, Hooft HJ, Ossewaarde JM. Bartonella serology for patients with intraocular inflammatory disease [published erratum appears in Retina 1999;19(3):260]. Retina 1998;18:348-55. Ref ID: 46 57. O'Halloran HS, Draud K, Minix M, Rivard AK, Pearson PA. Leber's neuroretinitis in a patient with serologic evidence of Bartonella eizabethae. Retina 1998;18:276-8. Ref ID: 49 58. Warren K, Goldstein E, Hung VS, Koehler JE, Richardson W. Use of retinal biopsy to diagnose Bartonella (formerly Rochalimaea) henselae retinitis in an HIV-infected patient. Archives of Ophthalmology 1998;116:937-40. Ref ID: 51 59. Ormerod LD, Skolnick KA, Menosky MM, Pavan PR, Pon DM. Retinal and choroidal manifestations of cat-scratch disease [see comments]. [Review] [41 refs]. Ophthalmology 1998;105:1024-31. Ref ID: 54 60. Reed JB, Scales DK, Wong MT, Lattuada CP, Jr., Dolan MJ, Schwab IR. Bartonella henselae neuroretinitis in cat scratch disease. Diagnosis, management, and sequelae [see comments]. Ophthalmology 1998;105:459-66. Ref ID: 56 61. McGrath N, Wallis W, Ellis-Pegler R, Morris AJ, Taylor W. Neuroretinitis and encephalopathy due to Bartonella henselae infection [letter]. Australian & New Zealand Journal of Medicine 1997;27:454. Ref ID: 57 62. Cunningham ET, Jr., McDonald HR, Schatz H, Johnson RN, Ai E, Grand MG. Inflammatory mass of the optic nerve head associated with systemic Bartonella henselae infection [letter]. Archives of Ophthalmology 1997;115:1596-7. Ref ID: 60 63. Jones MR,.Cunningham ET, Jr. Bartonella henselae-associated acute multifocal retinitis in a patient with acquired immunodeficiency syndrome. Retina 1997;17:457-9. Ref ID: 63 64. Cunningham ET, Jr., Schatz H, McDonald HR, Johnson RN. Acute multifocal retinitis. American Journal of Ophthalmology 1997;123:347-57. Ref ID: 68 65. Bafna S,.Lee AG. Bilateral optic disc edema and multifocal retinal lesions without loss of vision in cat scratch disease [letter]. Archives of Ophthalmology 1996;114:1016-7. Ref ID: 84 227 66. Maxwell SM. Sudden onset of blurred vision in a thirteen-year-old girl. Pediatric Infectious Disease Journal 1019;14:1016. Ref ID: 90 67. Wong MT, Dolan MJ, Lattuada CP, Jr., Regnery RL, Garcia ML, Mokulis EC et al. Neuroretinitis, aseptic meningitis, and lymphadenitis associated with Bartonella (Rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1. Clinical Infectious Diseases 1995;21:352-60. Ref ID: 91 68. McCrary B, Cockerham W, Pierce P. Neuroretinitis in cat-scratch disease associated with the macular star [letter]. Pediatric Infectious Disease Journal 1994;13:838-9. Ref ID: 101 Bartonella and Chronic Disease - science citation index search 1 Berdague P, Clave D, Archambaud M, Roux D, Casteignau G, Galinier M et al. Bartonella endocarditis on native valves: Two case reports. Archives Des Maladies Du Coeur Et Des Vaisseaux 1998;91:1277-81. 2 Dehio C. Pathogenesis of Bartonella (Rochalimaea) infections. Bulletin De L Institut Pasteur 1997;95:197-207. 3 Jacoby GA, Hay CM, Colvin RB, Walker BD. A 38-year-old man with digital clubbing, low-grade fever, and a murmur - Bartonella endocarditis, probably due to Bartonella quintana. New England Journal Of Medicine 1997;336:205-10. 4 Maurin M,.Raoult D. Bartonella infections: diagnostic and management issues. Current Opinion In Infectious Diseases 1998;11:189-93. 5 Raoult D. Afebrile blood culture-negative endocarditis. Annals Of Internal Medicine 1999;131:144-6. HELICOBACTER PYLORI Occupational relevance 1. Banatvala N, Abdi Y, Clements L, Herbert AM, Davies J, Bagg J et al. Helicobacter pylori infection in dentists--a case-control study. Scandinavian Journal of Infectious Diseases 1995;27:149-51. Ref ID: 263 2. Braden B, Duan LP, Caspary WF, Lembcke B. Endoscopy is not a risk factor for Helicobacter pylori infection--but medical practice is. Gastrointestinal Endoscopy 1997;46:305-10. Ref ID: 120 3. Chong J, Marshall BJ, Barkin JS, McCallum RW, Reiner DK, Hoffman SR et al. Occupational exposure to Helicobacter pylori for the endoscopy professional: a sera epidemiological study. American Journal of Gastroenterology 1994;89:1987-92. Ref ID: 257 228 4. Dore-Davin C, Heitz M, Yang H, Herranz M, Blum AL, Corthesy-Theulaz I. Helicobacter pylori in the oral cavity reflects handling of contaminants but not gastric infection. Digestion 1999;60:196-202. Ref ID: 3277 5. Drechsler J, Heinen E, Schauer M, Wulff U, Kessel R. Seroprevalence rates of Helicobacter pylori infection in staff ob Lubeck children's day centers. Arbeitsmedizin Sozialmedizin Umweltmedizin 1999;34:16-21. Ref ID: 3183 6. Fox JG. Non-human reservoirs of Helicobacter pylori. [Review] [83 refs]. Alimentary Pharmacology & Therapeutics 1995;9 Suppl 2:93-103. Ref ID: 241 7. Friis L, Engstrand L, Edling C. Prevalence of Helicobacter pylori infection among sewage workers. Scandinavian Journal of Work, Environment & Health 1996;22:364-8. Ref ID: 2948 8. Gasbarrini G, Pretolani S, Bonvicini F, Gatto MR, Tonelli E, Megraud F et al. A population based study of Helicobacter pylori infection in a European country: the San Marino Study. Relations with gastrointestinal diseases. Gut 1995;36:838-44. Ref ID: 239 9. Hammermeister I, Janus G, Schamarowski F, Rudolf M, Jacobs E, Kist M. Elevated risk of Helicobacter pylori infection in submarine crews. European Journal of Clinical Microbiology & Infectious Diseases 1992;11:9-14. Ref ID: 339 10. Hovelius B, Andersson SI, Hagander B, Molstad S, Reimers P, Sperlich E et al. Dyspepsia in general practice: history and symptoms in relation to Helicobacter pylori serum antibodies. Scandinavian Journal of Gastroenterology 1994;29:506-10. Ref ID: 226 11. Husson MO, Vincent P, Grabiaud MH, Furon D, Leclerc H. Anti-Helicobacter pylori IgG levels in abattoir workers. Gastroenterologie Clinique et Biologique 1991;15:723-6. Ref ID: 343 12. Hwang H, Dwyer J, Russell RM. Diet, Helicobacter pylori infection, food preservation and gastric cancer risk: are there new roles for preventative factors?. [Review] [57 refs]. Nutrition Reviews 1994;52:75-83. Ref ID: 225 13. Katelaris P, Tippett G, Zoli G, Lowe D, Norbu P, Farthing M. An evaluation of factors affecting Helicobacter pylori prevalence in Tibetans exiled in India. Transactions of the Royal Society of Tropical Medicine & Hygiene 1993;87:400-3. Ref ID: 25 14. Lin SK, Lambert JR, Schembri MA, Nicholson L, Korman MG. Helicobacter pylori prevalence in endoscopy and medical staff. Journal of Gastroenterology & Hepatology 1994;9:319-24. Ref ID: 212 229 15. Lin SK, Lambert JR, Schembri MA, Nicholson L, Johnson IH. The prevalence of Helicobacter pylori in practising dental staff and dental students. Australian Dental Journal 1998;43:35-9. Ref ID: 91 16. Luzza F, Maletta M, Imeneo M, Fabiano E, Doldo P, Biancone L et al. Evidence against an increased risk of Helicobacter pylori infection in dentists: a serological and salivary study. European Journal of Gastroenterology & Hepatology 1995;7:773-6. Ref ID: 208 17. Malaty HM, Evans DJ, Jr., Abramovitch K, Evans DG, Graham DY. Helicobacter pylori infection in dental workers: a seroepidemiology study. American Journal of Gastroenterology 1992;87:1728-31. Ref ID: 313 18. Matysiak-Budnik T, Briet F, Heyman M, Megraud F. Laboratory-acquired Helicobacter pylori infection [letter] [see comments]. Lancet 1995;346:1489-90. Ref ID: 685 19. Milne R, Logan RP, Harwood D, Misiewicz JJ, Forman D. Helicobacter pylori and upper gastrointestinal disease: a survey of gastroenterologists in the United Kingdom. Gut 1995;37:314-8. Ref ID: 201 20. Mitchell HM, Lee A, Carrick J. Increased incidence of Campylobacter pylori infection in gastroenterologists: further evidence to support person-to-person transmission of C. pylori. Scandinavian Journal of Gastroenterology 1989;24:396-400. Ref ID: 371 21. Morris A, Nicholson G, Lloyd G, Haines D, Rogers A, Taylor D. Seroepidemiology of Campylobacter pyloridis. New Zealand Medical Journal 1986;99:657-9. Ref ID: 11 22. Nguyen AM, el Zaatari FA, Graham DY. Helicobacter pylori in the oral cavity. A critical review of the literature. [Review] [47 refs]. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontics 1995;79:705-9. Ref ID: 197 23. Parsonnet J, Blaser MJ, Perez-Perez GI, Hargrett-Bean N, Tauxe RV. Symptoms and risk factors of Helicobacter pylori infection in a cohort of epidemiologists. Gastroenterology 1992; 102:41-6. Ref ID: 341 24. Potts LF, Lewis SJ, Mountford RA. Prevalence of Helicobacter pylori in respiratory physicians performing bronchoscopy: a comparison with gastroenterologists using the carbon 13 urea breath test. Helicobacter 1997;2:152-4. Ref ID: 116 25. Rae AJ, Bathe OF, Cleator IG. Helicobacter pylori infection in gastroenterology clinic personnel [letter]. Journal of Hospital Infection 1994;27:241-2. Ref ID: 188 230 26. Raymond J, Bingen E, Brahimi N, Bergeret M, Kalach N. Randomly amplified polymorphic DNA analysis in suspected laboratory Helicobacter pylori infection [letter; comment]. Lancet 1996;347:975. Ref ID: 698 27. Rocha GA, Queiroz DM, Mendes EN, Oliveira AM, Moura SB, Silva RJ. Source of Helicobacter pylori infection: studies in abattoir workers and pigs [letter] [see comments]. American Journal of Gastroenterology 1992;87:1525. Ref ID: 856 28. Rothenbacher D, Peter R, Bode G, Adler G, Brenner H. Dyspepsia in relation to Helicobacter pylori infection and psychosocial work stress in white collar employees. American Journal of Gastroenterology 1998;93:1443-9. Ref ID: 85 29. Rudi J, Toppe H, Marx N, Zuna I, Theilmann L, Stremmel W et al. Risk of infection with Helicobacter pylori and hepatitis A virus in different groups of hospital workers. American Journal of Gastroenterology 1997;92:258-62. Ref ID: 3050 30. Schmid K,.Weber A. Risk of occupational infection with Helicobacter pylori in the health service. Arbeitsmedizin Sozialmedizin Umweltmedizin 1996;31:203-9. Ref ID: 2211 31. Shelley KH,.Haddadin AS. Is Helicobacter pylori infection an occupational hazard for anesthesiologists? Anesthesia & Analgesia 1998;87:973-4. Ref ID: 2379 32. Shinchi K, Kono S, Imanishi K. Helicobacter pylori infection and gastroduodenal ulcer in self-defense officials in Japan [letter]. Scandinavian Journal of Gastroenterology 1996;31:1136. Ref ID: 163 33. Su Y-C, Wang W-M, Chen L-T, Chiang W, Chen C-Y, Lu S-N et al. High seroprevalence of IgG against Helicobacter pylori among endoscopists in Taiwan. Digestive Diseases & Sciences 1996;41:1571-6. Ref ID: 2950 34. Takata T, Shirotani T, Okada M, Kanda M, Fujimoto S, Ono J. Acute hemorrhagic gastropathy with multiple shallow ulcers and duodenitis caused by a laboratory infection of Helicobacter pylori. Gastrointestinal Endoscopy 1998;47:291-4. Ref ID: 658 35. Vaira D, Holton J, Londei M, Beltrandi E, Salmon PR, D'Anastasio C et al. Campylobacter pylori in abattoir workers: Is it a zoonosis? Lancet 1988;2:725-6. Ref ID: 3805 36. Vaira D, Holton J, Ainley CC, Lonedi M, Romanos A, Maldini M et al. The source of Campylobacter pylori. Biomedicine & Pharmacotherapy 1989;43:447-50. Ref ID: 391 37. Veldhuyzen van Zanten SJ. Do socio-economic status, marital status and occupation influence the prevalence of Helicobacter pylori infection?. [Review] [35 refs]. Alimentary Pharmacology & Therapeutics 1995;9 Suppl 2:41-4. Ref ID: 172 231 38. Wilhoite SL, Ferguson JD, Soike DR, Kalbfleisch JH, Thomas E. Increased prevalence of Helicobacter pylori antibodies among nurses. Archives of Internal Medicine 1993;153 :708-12. Ref ID: 4138 HELICOBACTER PYLORI AND CORONARY HEART DISEASE Helicobacter pylori and coronary heart disease – medline search 1. Arbustini E, Morbini P, Bello BD, Prati F, Specchia G. From plaque biology to clinical setting [see comments]. [Review] [60 refs]. American Heart Journal 1999; 138: S55- S60. Ref ID: 4 2. Famularo G, Trinchieri V, Santini G, De Simone C. Infections, atherosclerosis, and coronary heart disease. [Review] [115 refs]. Annali Italiani di Medicina Interna 2000;15:144- 55. Ref ID: 5 3. Fong IW. Emerging relations between infectious diseases and coronary artery disease and atherosclerosis. [Review] [95 refs]. CMAJ 2000;163:49-56. Ref ID: 9 4. Leinonen M,.Saikku P. Infections and atherosclerosis. [Review] [118 refs]. Scandinavian Cardiovascular Journal 2000;34:12-20. Ref ID: 15 5. de Boer OJ, van der Wal AC, Becker AE. Atherosclerosis, inflammation, and infection. [Review] [64 refs]. Journal of Pathology 2000;190:237-43. Ref ID: 31 6. Wierzbicki WB,.Hagmeyer KO. Helicobacter pylori, Chlamydia pneumoniae, and cytomegalovirus: chronic infections and coronary heart disease. [Review] [75 refs]. Pharmacotherapy 2000;20:52-63. 7. Kusters JG,.Kuipers EJ. Helicobacter and atherosclerosis. [Review] [49 refs]. American Heart Journal 1999;138:S523-S527. Ref ID: 49 8. Danesh J. Coronary heart disease, Helicobacter pylori, dental disease, Chlamydia pneumoniae, and cytomegalovirus: meta-analyses of prospective studies. American Heart Journal 1999;138:S434-S437. Ref ID: 50 9. Pellicano R, Broutet N, Ponzetto A, Megraud F. Helicobacter pylori: from the stomach to the heart. [Review] [27 refs]. European Journal of Gastroenterology & Hepatology 1999;11:1335-7. Ref ID: 53 10. Meier CR. The possible role of infections in acute myocardial infarction. [Review] [97 refs]. Biomedicine & Pharmacotherapy 1999;53:397-404. Ref ID: 54 232 11. Schussheim AE,.Fuster V. Antibiotics for myocardial infarction? A possible role of infection in atherogenesis and acute coronary syndromes. [Review] [52 refs]. Drugs 1999;57:283-91. Ref ID: 61 12. Tsang KW,.Lam SK. Helicobacter pylori and extra-digestive diseases. [Review] [68 refs]. Journal of Gastroenterology & Hepatology 1999;14:844-50. Ref ID: 67 13. Pellicano R, Mladenova I, Broutet N, Salmi LR, Megraud F. Is there an association between Helicobacter pylori infection and coronary heart disease? European Journal of Epidemiology 1999;15:611-9. Ref ID: 68 14. Cammarota G, Pasceri V, Papa A, Cianci R, Gasbarrini A, Fedeli P et al. Helicobacter pylori infection and ischaemic heart disease. [Review] [12 refs]. Italian Journal of Gastroenterology & Hepatology 1998;30 Suppl 3:S304-S306. Ref ID: 74 15. Danesh J. Is there a link between chronic Helicobacter pylori infection and coronary heart disease?. [Review] [31 refs]. European Journal of Surgery - Supplement 1998;27-31. Ref ID: 76 16. Danesh J,.Peto R. Risk factors for coronary heart disease and infection with Helicobacter pylori: meta-analysis of 18 studies. BMJ 1998;316:1130-2. Ref ID: 106 17. Wisniewski RM,.Peura DA. Helicobacter pylori: beyond peptic ulcer disease [see comments]. [Review] [118 refs]. Gastroenterologist 1997;5:295-305. Ref ID: 114 18. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? [see comments]. [Review] [62 refs]. Lancet 1997;350:430-6. 19. Ellis RW. Infection and coronary heart disease. [Review] [44 refs]. Journal of Medical Microbiology 1997;46:535-9. Ref ID: 133 20. Danesh J, Whincup P, Walker M, Lennon L, ThoMSon A, Appleby P et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses [see comments]. BMJ 2000;321:199-204. Ref ID: 6 21. Roivainen M, Viik-Kajander M, Palosuo T, Toivanen P, Leinonen M, Saikku et al. Infections, inflammation, and the risk of coronary heart disease. Circulation 2000;101:252-7. Ref ID: 43 22. Folsom AR, Nieto FJ, Sorlie P, Chambless LE, Graham DY. Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators. Circulation 1998;98:845-50. Ref ID: 94 233 23. Ossewaarde JM, Feskens EJ, De Vries A, Vallinga CE, Kromhout D. Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not. Epidemiology & Infection 1998;120:93-9. Ref ID: 108 24. Whincup PH, Mendall MA, Perry IJ, Strachan DP, Walker M. Prospective relations between Helicobacter pylori infection, coronary heart disease, and stroke in middle aged men [see comments]. Heart 1996;75:568-72. Ref ID: 144 25. Danesh J, Youngman L, Clark S, Parish S, Peto R, Collins R. Helicobacter pylori infection and early onset myocardial infarction: case-control and sibling pairs study [see comments]. BMJ 1999;319:1157-62. Ref ID: 12 26. Tsai CJ,.Huang TY. Relation of Helicobacter pylori infection and angiographically demonstrated coronary artery disease. Digestive Diseases & Sciences 2000;45:1227-32. Ref ID: 17 27. Pellicano R, Mazzarello MG, Morelloni S, Allegri M, Arena V, Ferrari M et al. Acute myocardial infarction and Helicobacter pylori seropositivity. International Journal of Clinical & Laboratory Research 1999;29:141-4. Ref ID: 25 28. Pieniazek P, Karczewska E, Duda A, Tracz W, Pasowicz M, Konturek SJ. Association of Helicobacter pylori infection with coronary heart disease. Journal of Physiology & Pharmacology 1999;50:743-51. Ref ID: 34 29. Ammann P, Marschall S, Kraus M, Schmid L, Angehrn W, Krapf R et al. Characteristics and prognosis of myocardial infarction in patients with normal coronary arteries. Chest 2000;117:333-8. Ref ID: 41 30. Colizzi C, Rizzello V, Angiolillo DJ, Liuzzo G, Ginnetti F, Monaco C et al. In vitro hyperreactivity to lipopolysaccharide in patients with history of unstable angina is not associated with seropositivity for Cytomegalovirus, Helicobacter pylori and Chlamydia pneumoniae. Cardiologia 1999;44:377-80. Ref ID: 59 31. Quinn MJ, Foley JB, Mulvihill NT, Lee J, Crean PA, Walsh MJ et al. Helicobacter pylori serology in patients with angiographically documented coronary artery disease. American Journal of Cardiology 1906;83:1664-6. Ref ID: 60 32. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999; 81:245-7. Ref ID: 62 33. de Luis DA, Lahera M, Canton R, Boixeda D, San Roman AL, Aller R et al. Association of Helicobacter pylori infection with cardiovascular and cerebrovascular disease in diabetic patients. Diabetes Care 1998;21:1129-32. Ref ID: 93 234 34. Khurshid A, Fenske T, Bajwa T, Bourgeois K, Vakil N. A prospective, controlled study of Helicobacter pylori seroprevalence in coronary artery disease. American Journal of Gastroenterology 1998;93:717-20. Ref ID: 96 35. Anderson JL, Carlquist JF, Muhlestein JB, Horne BD, Elmer SP. Evaluation of C reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction. Journal of the American College of Cardiology 1998;32:35-41. Ref ID: 97 36. Ossei-Gerning N, Moayyedi P, Smith S, Braunholtz D, Wilson JI, Axon AT et al. Helicobacter pylori infection is related to atheroma in patients undergoing coronary angiography. Cardiovascular Research 1997;35:120-4. Ref ID: 126 37. Rathbone B, Martin D, Stephens J, Thompson JR, Samani NJ. Helicobacter pylori seropositivity in subjects with acute myocardial infarction. Heart 1996;76:308-11. Ref ID: 140 38. Mendall MA, Goggin PM, Molineaux N, Levy J, Toosy T, Strachan D et al. Relation of Helicobacter pylori infection and coronary heart disease. British Heart Journal 1994;71:437-9. Ref ID: 165 39. Niemela S, Karttunen T, Korhonen T, Laara E, Karttunen R, Ikaheimo M et al. Could Helicobacter pylori infection increase the risk of coronary heart disease by modifying serum lipid concentrations? Heart 1996;75:573-5. Ref ID: 145 40. Pellicano R, Parravicini PP, Bigi R, La Rovere MT, Baduini G, Gandolfo et al. Patients with acute myocardial infarction in northern Italy are often infected by Helicobacter pylori. Panminerva Medica 1999;41:279-82. Ref ID: 30 41. Bielanski W. Epidemiological study on Helicobacter pylori infection and extragastroduodenal disorders in Polish population. Journal of Physiology & Pharmacology 1999;50:723-33. Ref ID: 35 42. Gunn M, Stephens JC, Thompson JR, Rathbone BJ, Samani NJ. Significant association of cagA positive Helicobacter pylori strains with risk of premature myocardial infarction. Heart 2000;84:267-71. Ref ID: 3 43. Whincup P, Danesh J, Walker M, Lennon L, ThoMSon A, Appleby P et al. Prospective study of potentially virulent strains of Helicobacter pylori and coronary heart disease in middle-aged men. Circulation 2000;101:1647-52. Ref ID: 27 44. Schweeger I, Fitscha P, Sinzinger H. Successful eradication of Helicobacter pylori as determined by ((13))C-urea breath test does not alter fibrinogen and acute phase response markers. Thrombosis Research 2000;97:411-20. Ref ID: 29 235 45. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Association of Helicobacter pylori infection with elevated serum lipids [see comments]. Atherosclerosis 1999;142:207-10. Ref ID: 39 45. Abdelmouttaleb I, Danchin N, Ilardo C, Aimone-Gastin I, Angioi M, Lozniewski A et al. C-Reactive protein and coronary artery disease: additional evidence of the implication of an inflammatory process in acute coronary syndromes [see comments]. American Heart Journal 1999;137:346-51. Ref ID: 44 46. Brenner H, Berg G, Frohlich M, Boeing H, Koenig W. Chronic infection with Helicobacter pylori does not provoke major systemic inflammation in healthy adults: results from a large population-based study. Atherosclerosis 1999;147:399-403. Ref ID: 46 47. Koenig W, Rothenbacher D, Hoffmeister A, Miller M, Bode G, Adler G et al. Infection with Helicobacter pylori is not a major independent risk factor for stable coronary heart disease: lack of a role of cytotoxin-associated protein A-positive strains and absence of a systemic inflammatory response. Circulation 1999;100:2326-31. Ref ID: 47 48. Birnie DH, Holme ER, McKay IC, Hood S, McColl KE, Hillis WS. Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk [see comments]. European Heart Journal 1998;19:387-94. Ref ID: 101 49. Regnstrom J, Jovinge S, Bavenholm P, Ericsson CG, De Faire U, HaMSten A et al. Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degree of coronary artery disease. Journal of Internal Medicine 1998;243:109-13. Ref ID: 107 50. Markle HV. Coronary artery disease associated with Helicobacter pylori infection is at least partially due to inadequate folate status. [Review] [26 refs]. Medical Hypotheses 1997; 49:289-92. Ref ID: 118 52 . McDonagh TA, Woodward M, Morrison CE, McMurray JJ, Tunstall-Pedoe H, Lowe GD et al. Helicobacter pylori infection and coronary heart disease in the North Glasgow MONICA population [see comments]. European Heart Journal 1997;18 :1257-60. Ref ID: 112 53. Mendall MA, Patel P, Ballam L, Strachan D, Northfield TC. C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study [see comments]. BMJ 1996;312:1061-5. Ref ID: 150 54. Patel P, Mendall MA, Carrington D, Strachan DP, Leatham E, Molineaux N et al. Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors [see comments] [published erratum appears in BMJ 1995 Oct 14;311(7011):985]. BMJ 1995;311:711-4. Ref ID: 156 236 55. Bielanski W. Epidemiological study on Helicobacter pylori infection and extragastroduodenal disorders in Polish population. Journal of Physiology & Pharmacology 1999;50:723-33. Ref ID: 35 56. Cheng TO. Atherosclerosis is not an infectious process [letter; comment]. Cardiology 1999;91:73. Ref ID: 38 57. Cremonini F, Gasbarrini A, Pola P. C-reactive protein and coronary disease [letter; comment]. American Heart Journal 1999;138:999-1000. Ref ID: 45 58. Delaney BC, Hobbs FD, Holder R. Association of Helicobacter pylori infection with coronary heart disease. Eradication of the infection on grounds of cardiovascular risk is not supported by current evidence [letter; comment]. BMJ 1996;312:251-2. Ref ID: 152 59. Ponzetto A, La Rovere MT, Sanseverino P, Bazzoli F. Association of Helicobacter pylori infection with coronary heart disease. Study confirms previous findings [letter; comment]. BMJ 1996;312:251. Ref ID: 153 60. Sandifer QD, Vuilo S, Crompton G. Association of Helicobacter pylori infection with coronary heart disease. Association may not be causal [letter; comment]. BMJ 1996;312:251. Ref ID: 154 61. Lip GH, Wise R, Beevers G. Association of Helicobacter pylori infection with coronary heart disease. Study shows association between H.pylori infection and hypertension [letter; comment]. BMJ 1996;312:250-1. Ref ID: 155 62. Martin-de-Argila C, Boixeda D, Canton R, Gisbert JP, Fuertes A. High seroprevalence of Helicobacter pylori infection in coronary heart disease [letter; comment]. Lancet 1995;346:310. Ref ID: 157 63. Miragliotta G, Del Prete R, Mosca A. Helicobacter pylori infection and coronary heart disease [letter; comment]. Lancet 1994;344:751. Ref ID: 162 Helicobacter pylori and Coronary Heart Disease - science citation index search 1 Spinola-Klein C, Rupprecht HJ, Blankenberg S, Bickel C, Kopp H, Rippin G et al. Are morphological or functional changes in the carotid artery wall associated with Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, or herpes simplex virus infection? Stroke 2000;31:2127-33. HELICOBACTER PYLORI AND CROHN'S DISEASE Helicobacter and Crohn's Disease – medline search 1. Riddell RH. Pathobiology of Helicobacter pylori infection in children. [Review] [48 refs]. Canadian Journal of Gastroenterology 1999;13:599-603. Ref ID: 52 237 2. Pellicano R, Broutet N, Ponzetto A, Megraud F. Helicobacter pylori: from the stomach to the heart. [Review] [27 refs]. European Journal of Gastroenterology & Hepatology 1999;11:1335-7. Ref ID: 53 3. Blecker U,.Gold BD. Gastritis and peptic ulcer disease in childhood. [Review] [62 refs]. European Journal of Pediatrics 1999;158:541-6. Ref ID: 57 4. Prantera C,.Scribano ML. Crohn's disease: the case for bacteria. [Review] [39 refs]. Italian Journal of Gastroenterology & Hepatology 1999;31:244-6. Ref ID: 58 5. Pena AS,.Crusius JB. Food allergy, coeliac disease and chronic inflammatory bowel disease in man. [Review] [29 refs]. Veterinary Quarterly 1998;20 Suppl 3:S49-S52. Ref ID: 88 6. Pearce CB, Duncan HD, Timmis L, Green JR. Assessment of the prevalence of infection with Helicobacter pylori in patients with inflammatory bowel disease. European Journal of Gastroenterology & Hepatology 2000;12:439-43. Ref ID: 18 7. Duggan AE, Usmani I, Neal KR, Logan RF. Appendicectomy, childhood hygiene, Helicobacter pylori status, and risk of inflammatory bowel disease: a case control study [see comments]. Gut 1998;43:494-8. Ref ID: 79 8. Wagtmans MJ, Witte AM, Taylor DR, Biemond I, Veenendaal RA, Verspaget et al. Low seroprevalence of Helicobacter pylori antibodies in historical sera of patients with Crohn's disease. Scandinavian Journal of Gastroenterology 1997;32:712-8. Ref ID: 130 9. Halme L, Rautelin H, Leidenius M, Kosunen TU. Inverse correlation between Helicobacter pylori infection and inflammatory bowel disease. Journal of Clinical Pathology 1996;49:65-7. Ref ID: 148 10. el Omar E, Penman I, Cruikshank G, Dover S, Banerjee S, WilliaMS C et al. Low prevalence of Helicobacter pylori in inflammatory bowel disease: association with sulphasalazine. Gut 1994;35:1385-8. Ref ID: 161 11. Sulik A, Kemona A, Sulik M, Oldak E. The gastrointestinal mast cell in health and disease. Roczniki Akademii Medycznej W BialyMStoku 1999;44:17-23. Ref ID: 37 12. Romagnani S. Th1/Th2 cells. [Review] [131 refs]. Inflammatory Bowel Diseases 1999;5:285-94. Ref ID: 51 13. Duchmann R, Marker-Hermann E, Meyer zum Buschenfelde KH. Bacteria-specific T-cell clones are selective in their reactivity towards different enterobacteria or H. pylori and increased in inflammatory bowel disease. Scandinavian Journal of Immunology 1996;44:71- 9. Ref ID: 146 238 14. Trejdosiewicz LK, Calabrese A, Smart CJ, Oakes DJ, Howdle PD, Crabtree et al. Gamma delta T cell receptor-positive cells of the human gastrointestinal mucosa: occurrence and V region gene expression in Helicobacter pylori-associated gastritis, coeliac disease and inflammatory bowel disease. Clinical & Experimental Immunology 1991;84:440-4. Ref ID: 174 15. Parente F, Cucino C, Bollani S, Imbesi V, Maconi G, Bonetto S et al. Focal gastric inflammatory infiltrates in inflammatory bowel diseases: prevalence, immunohistochemical characteristics, and diagnostic role. American Journal of Gastroenterology 2000;95:705-11. Ref ID: 36 16. Pilotto A, Rumor F, Franceschi M, Leandro G, Novello R, Soffiati G et al. Lack of association between Helicobacter pylori infection and extracardiac atherosclerosis in dyspeptic elderly subjects. Age & Ageing 1999;28:367-71. Ref ID: 55 17. Basili S, Vieri M, Di Lecce VN, Maccioni D, Marmifero M, Paradiso M et al. Association between histological diagnosis of Helicobacter pylori and coronary heart disease: results of a retrospective study. Clinica Terapeutica 1998;149:413-7. Ref ID: 73 18. D'Inca R, Sturniolo G, Cassaro M, di Pace C, Longo G, Callegari I et al. Prevalence of upper gastrointestinal lesions and Helicobacter pylori infection in Crohn's disease. Digestive Diseases & Sciences 1998;43:988-92. Ref ID: 104 19. Parente F, Molteni P, Bollani S, Maconi G, Vago L, Duca PG et al. Prevalence of Helicobacter pylori infection and related upper gastrointestinal lesions in patients with inflammatory bowel diseases. A cross-sectional study with matching. Scandinavian Journal of Gastroenterology 1997;32:1140-6. Ref ID: 120 20. Puspok A, Dejaco C, Oberhuber G, Waldhor T, Hirschl AM, Vogelsang H et al. Influence of Helicobacter pylori infection on the phenotype of Crohn's disease. American Journal of Gastroenterology 1999;94:3239-44. Ref ID: 48 21. Kolho KL, Rautelin H, Lindahl H, Savilahti E. Helicobacter pylori-positive gastritis in pediatric patients with chronic inflammatory bowel disease. Journal of Pediatric Gastroenterology & Nutrition 1998;27:292-5. Ref ID: 83 22. L, Karkkainen P, Rautelin H, Kosunen TU, Sipponen P. High frequency of helicobacter negative gastritis in patients with Crohn's disease. Gut 1996;38:379-83. Ref ID: 147 SALMONELLA TYPHI Occupational relevance 1. Ashdown L,.Cassidy J. Successive Salmonella give and Salmonella typhi infections, laboratory-acquired. Pathology 1991;23:233-4. Ref ID: 929 239 2. Blaser MJ, Hickman FW, Farmer JJ, III, Brenner DJ, Balows A, Feldman RA. Salmonella typhi: the laboratory as a reservoir of infection. Journal of Infectious Diseases 1980;142:934-8. Ref ID: 411 3. Koay AS, Jegathesan M, Rohani MY, Cheong YM. Pulsed-field gel electrophoresis as an epidemiologic tool in the investigation of laboratory acquired Salmonella typhi infection. Southeast Asian Journal of Tropical Medicine & Public Health 1997;28:82-4. Ref ID: 126 4. Langeland G. Salmonella spp. in the working environment of sewage treatment plants in Oslo, Norway. Applied & Environmental Microbiology 1982;43:1111-5. Ref ID: 473 SALMONELLA TYPHI AND BILE TRACT NEOPLASM Salmonella typhi and bile tract neoplasm – medline search 1. Welton JC, Marr JS, Friedman SM. Association between hepatobiliary cancer and typhoid carrier state. Lancet 1979;1:791-4. Ref ID: 26 2. Shetty PB,.Broome DR. Sonographic analysis of gallbladder findings in Salmonella enteric fever. Journal of Ultrasound in Medicine 1998;17:231-7. Ref ID: 4 3. el Zayadi A, Ghoneim M, Kabil SM, el Tawil A, Sherif A, Selim O. Bile duct carcinoma in Egypt: possible etiological factors. Hepato-Gastroenterology 1991;38:337-40. Ref ID: 13 4. Ristori C, Rodriguez H, Vicent P, Lobos H, D'Ottone K, Garcia J et al. Investigation of the Salmonella typhi-paratyphi carrier state in cases of surgical intervention for gallbladder disease. Bulletin of the Pan American Health Organization 1982;16:161-71. Ref ID: 23 5 Shukla VK, Singh H, Pandey M, Upadhyay SK, Nath G. Carcinoma of the gallbladder--is it a sequel of typhoid? Digestive Diseases & Sciences 2000;45:900-3. Ref ID: 1 6 Dutta U, Garg PK, Kumar R, Tandon RK. Typhoid carriers among patients with gallstones are at increased risk for carcinoma of the gallbladder. American Journal of Gastroenterology 2000;95:784-7. Ref ID: 2 7. Nath G, Singh H, Shukla VK. Chronic typhoid carriage and carcinoma of the gallbladder. European Journal of Cancer Prevention 1997;6:557-9. Ref ID: 5 8. Lavergne GM, James HF, Martineau C, Diena BB, Lior H. The guinea pig as a model for the asymptomatic human typhoid carrier. Laboratory Animal Science 1977;27:806-16. Ref ID: 28 240 9. Arora HL,.Sangal BC. Salmonella typhi cholangitis in rats--an experimental study. Indian Journal of Pathology & Bacteriology 1973;16:28-34. Ref ID: 31 10. Glaz ET. Elimination of S. typhi from the organs of carrier mice by combined treatment with BCG and neomycin. Japanese Journal of Experimental Medicine 1971;41:581-6. Ref ID: 39 11. Verma M, Chhatwal J, Deodhar MC, Aneja R, Singh T. Enteric cholecystitis 15 years experience. Indian Pediatrics 1995;32:808-10. Ref ID: 6 12. Gosbell I, Jones PD, Matthews A, Yeo B. Surgical presentation of hepatobiliary disease due to Salmonella typhi. Australian & New Zealand Journal of Surgery 1995; 65: 898-9. Ref ID: 7 13. Thambidorai CR, Shyamala J, Sarala R, Vatsala RB, Tamizhisai S. Acute acalculous cholecystitis associated with enteric fever in children. Pediatric Infectious Disease Journal 1995;14:812-3. Ref ID: 8 14. Garg P, Singh R, Sharda A, Dadoo RC. Perforation in acute acalculus Salmonella cholecystitis. Tropical Doctor 1995;25:84. Ref ID: 9 15. Yulevich A, Cohen Z, Maor E, Bryk T, Mares AJ. Acute acalculous cholecystitis caused by Salmonella typhi in a 6-year-old child. European Journal of Pediatric Surgery 1992;2:301-3. Ref ID: 11 16. Avalos ME, Cerulli MA, Lee RS. Acalculous acute cholecystitis due to Salmonella typhi [see comments]. Digestive Diseases & Sciences 1992;37:1772-5. Ref ID: 12 17. Winkler AP,.Gleich S. Acute acalculous cholecystitis caused by Salmonella typhi in an 11-year-old. Pediatric Infectious Disease Journal 1988;7:125-8. Ref ID: 17 18. Sinnott CR,.Teall AJ. Persistent gallbladder carriage of Salmonella typhi [letter]. Lancet 1987;1:976. Ref ID: 18 19. Shpargel JS, Berardi RS, Lenz D. Salmonella typhi carrier state 52 years after illness with typhoid fever: a case study. American Journal of Infection Control 1985;13:122-3. Ref ID: 19 20. Lewis GJ. A rare cause of cholecystitis in pregnancy. International Journal of Gynaecology & Obstetrics 1983;21:175-7. Ref ID: 21 241 21. Ristori C, Rodriguez H, Vicent P, Ferreccio C, Garcia J, Lobos H et al. Persistence of the Salmonella typhi-paratyphi carrier state after gallbladder removal. Bulletin of the Pan American Health Organization 1982;16:361-6. Ref ID: 22 22. Flight RJ. Chronic typhoid infection in a normally functioning gall bladder. New Zealand Medical Journal 1972;76:345-7. Ref ID: 33 23. Reisig G,.Schaffner W. Postoperative detection of Salmonella typhi. An unexpected hospital infection hazard. Archives of Surgery 1972;104:349-50. Ref ID: 37 24 Axelrod L, Munster AM, O'Brien TF. Typhoid cholecystitis and gallbladder carcinoma after interval of 67 years. JAMA 1971;217:83. Ref ID: 40 Salmonella typhi and bile tract neoplasm - science citation index search 1 Caygill CPJ, Braddick M, Hill MJ, Knowles RL, Sharp JCM. The association between typhoid carriage, typhoid infection and subsequent cancer at a number of sites. European Journal Of Cancer Prevention 1995;4:187-93. 2 Roa I, Ibacache G, Carvallo J, Melo A, Araya J, De Aretxabala X et al. Microbiological study of gallbladder bile in a high risk zone for gallbladder cancer. Revista Medica De Chile 1999;127:1049-55. 3 Simmers TA, Mijnhout GS, VanMeyel JJM. Salmonellosis: An unusual complication of hepatocellular carcinoma. Scandinavian Journal Of Gastroenterology 1997;32:1181-2. CAMPYLOBACTER Occupational relevance 1. Chattopadhyay UK, Rathore RS, Pal D, Das MS. Incidence of Campylobacter species in animal handlers. Indian Journal of Medical Research 1992;95:31-3. Ref ID: 336 2. Ellis A, Irwin R, Hockin J, Borczyk A, Woodward D, Johnson W. Outbreak of Campylobacter infection among farm workers: an occupational hazard. Canada Communicable Disease Report 1995;21:153-6. Ref ID: 246 3. Fox JG, Taylor NS, Penner JL, Shames B, Gurgis RV, ToMSon FN. Investigation of zoonotically acquired Campylobacter jejuni enteritis with serotyping and restriction endonuclease DNA analysis. Journal of Clinical Microbiology 1989;27:2423-5. Ref ID: 899 4. Jan D, Sortais A, Attiogbe M, Geslin C, Piolet MC. Bacteremia endocarditis and Campylobacter fetus meningitis in a farmer. Medecine et Maladies Infectieuses 2000; 30 : 173 4. Ref ID: 2552 242 5. Logan JMJ, Burnens A, Linton D, Lawson AJ, Stanley J. Campylobacter lanienae sp. nov., a new species isolated from workers in an abattoir. Int J Syst Evol Microbiol, Vol 50(2) (pp 865-872), 2000 0 AD. Ref ID: 2651 6. Mancinelli S, Palombi L, Riccardi F, Marazzi MC. Serological study of Campylobacter jejuni infection in slaughterhouse workers [letter]. Journal of Infectious Diseases 1987;156:856. Ref ID: 873 7. Mitchell HM, Lee A, Carrick J. Increased incidence of Campylobacter pylori infection in gastroenterologists: further evidence to support person-to-person transmission of C. pylori. Scandinavian Journal of Gastroenterology 1989;24:396-400. Ref ID: 371 8. Oates JD,.Hodgin UG, Jr. Laboratory-acquired Campylobacter enteritis. Southern Medical Journal 1981;74:83. Ref ID: 776 9. Penner JL, Hennessy JN, Mills SD, Bradbury WC. Application of serotyping and chromosomal restriction endonuclease digest analysis in investigating a laboratory-acquired case of Campylobacter jejuni enteritis. Journal of Clinical Microbiology 1983;18:1427-8. Ref ID: 767 10. Vaira D, Holton J, Londei M, Beltrandi E, Salmon PR, D'Anastasio C et al. Campylobacter pylori in abottoir workers: Is it a zoonosis? Lancet 1988;2:725-6. Ref ID: 3805 CAMPYLOBACTER AND REACTIVE ARTHRITIS AND REITER'S DISEASE Campylobacter and Reactive Arthritis and Reiter's Disease medline search 1. Altekruse SF, Stern NJ, Fields PI, Swerdlow DL. Campylobacter jejuni--an emerging foodborne pathogen. [Review] [21 refs]. Emerging Infectious Diseases 1999;5:28-35. Ref ID: 6 2. Koehler L, Zeidler H, Hudson AP. Aetiological agents: their molecular biology and phagocyte-host interaction. [Review] [64 refs]. Baillieres Clinical Rheumatology 1998;12:589-609. Ref ID: 10 3. Altekruse SF, Swerdlow DL, Stern NJ. Microbial food borne pathogens. Campylobacter jejuni. [Review] [68 refs]. Veterinary Clinics of North America - Food Animal Practice 1998;14:31-40. Ref ID: 12 4. McDowell RM,.McElvaine MD. Long-term sequelae to foodborne disease. [Review] [21 refs]. Revue Scientifique et Technique 1997;16:337-41. Ref ID: 15 5. Scott DA. Vaccines against Campylobacter jejuni. [Review] [89 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S183-S188. Ref ID: 16 243 6. Sieper J, Kingsley GH, Marker-Hermann E. Aetiological agents and immune mechanisms in enterogenic reactive arthritis. [Review] [83 refs]. Baillieres Clinical Rheumatology 1996;10:105-21. Ref ID: 22 7. Svenungsson B. Reactive arthritis [editorial]. [Review] [52 refs]. International Journal of STD & AIDS 1995;6:156-60. Ref ID: 26 8. Peterson MC. Clinical aspects of Campylobacter jejuni infections in adults [see comments]. [Review] [71 refs]. Western Journal of Medicine 1994;161:148-52. Ref ID: 33 9. Peterson MC. Rheumatic manifestations of Campylobacter jejuni and C. fetus infections in adults. [Review] [50 refs]. Scandinavian Journal of Rheumatology 1994;23:167- 70. Ref ID: 34 10. Kingsley GH. Reactive arthritis: a paradigm for inflammatory arthritis. [Review] [59 refs]. Clinical & Experimental Rheumatology 1993;11 Suppl 8:S29-S36. Ref ID: 42 11. Keat A,.Rowe I. Reiter's syndrome and associated arthritides. [Review] [40 refs]. Rheumatic Diseases Clinics of North America 1991;17:25-42. 12. Nickerson CL, Luthra HS, David CS. Role of enterobacteria and HLA-B27 in spondyloarthropathies: studies with transgenic mice. [Review] [116 refs]. Annals of the Rheumatic Diseases 1990;49:426-33. Ref ID: 57 13. Schaad UB. Reactive arthritis associated with Campylobacter enteritis. Pediatric Infectious Disease 1982;1:328-32. Ref ID: 100 14. Schmidt U, Chmel H, Kaminski Z, Sen P. The clinical spectrum of Campylobacter fetus infections: report of five cases and review of the literature. Quarterly Journal of Medicine 1980;49:431-42. Ref ID: 109 15. Toivanen A, Yli-Kerttula T, Luukkainen R, Merilahti-Palo R, Granfors K, Seppala J. Effect of antimicrobial treatment on chronic reactive arthritis. Clinical & Experimental Rheumatology 1993;11:301-7. Ref ID: 39 16. Chou CT, Uksila J, Toivanen P. Enterobacterial antibodies in Chinese patients with rheumatoid arthritis and ankylosing spondylitis [see comments]. Clinical & Experimental Rheumatology 1998;16:161-4. Ref ID: 1 17. Janvier B, Ayraud S, Beby-Defaux A, Louis FJ. Immunogens of interest for the diagnosis of Campylobacter jejuni infections. FEMS Immunology & Medical Microbiology 2000;27:263-8. Ref ID: 3 244 18. Aggarwal A, Misra R, Chandrasekhar S, Prasad KN, Dayal R, Ayyagari A. Is undifferentiated seronegative spondyloarthropathy a forme fruste of reactive arthritis? British Journal of Rheumatology 1997;36:1001-4. Ref ID: 17 19. Lapadula G, Iannone F, Covelli M, Numo R, Pipitone V. Anti-enterobacteria antibodies in psoriatic arthritis. Clinical & Experimental Rheumatology 1992;10:461-6. Ref ID: 44 20. Maki-Ikola O, Viljanen MK, Tiitinen S, Toivanen P, Granfors K. Antibodies to arthritis-associated microbes in inflammatory joint diseases. Rheumatology International 1991;10:231-4. Ref ID: 50 21. Lapadula G, Covelli M, Numo R. Antibacterial antibody pattern in seronegative spondyloarthropathies (SNSA). Clinical & Experimental Rheumatology 1988;6:385-90. Ref ID: 66 22. Bremell T, Bjelle A, Svedhem A. Rheumatic symptoms following an outbreak of campylobacter enteritis: a five year follow up. Annals of the Rheumatic Diseases 1991;50:934-8. 23. Melby K, Dahl OP, Crisp L, Penner JL. Clinical and serological manifestations in patients during a waterborne epidemic due to Campylobacter jejuni. Journal of Infection 1990;21:309-16. Ref ID: 54 24. Ponka A, Pitkanen T, Sarna S, Kosunen TU. Infection due to Campylobacter jejuni: a report of 524 outpatients. Infection 1984;12:175-8. Ref ID: 79 25. Eastmond CJ. Gram-negative bacteria and B27 disease. British Journal of Rheumatology 1983;22:67-74. Ref ID: 89 26. Eastmond CJ, Rennie JA, Reid TM. An outbreak of Campylobacter enteritis--a rheumatological followup survey. Journal of Rheumatology 1983;10:107-8. Ref ID: 98 27. Ebringer A,.Wilson C. HLA molecules, bacteria and autoimmunity. [Review] [77 refs]. Journal of Medical Microbiology 2000;49:305-11. Ref ID: 4 28. Locht H, Peen E, Skogh T. Antineutrophil cytoplasmic antibodies in reactive arthritis [see comments]. Journal of Rheumatology 1995;22:2304-6. Ref ID: 23 29. Hassell AB, Life PF, Viner NJ, Gaston JS. A longitudinal study of peripheral blood mononuclear cell proliferative responses to bacterial antigens in reactive arthritis. British Journal of Rheumatology 1994;33:210-4. Ref ID: 36 245 30. Ren MN, Zhang JJ, Nakayama A, Yu DT. Reactivity between monoclonal anti-HLA- B27 antibodies and bacterial components: is there a consensus of findings?. [Review] [16 refs]. Rheumatology International 1989;9:219-21. Ref ID: 62 31. Cavender DE,.Ziff M. Absence of Antienterobacteriaceae and anti-HLA-B27 antibodies in mitogen stimulated cultures of lymphocytes from patients with Reiter's syndrome and ankylosing spondylitis. Journal of Rheumatology 1988;15:315-20. Ref ID: 67 32. Cavender D,.Ziff M. Anti-HLA-B27 antibodies in sera from patients with gram negative bacterial infections. Arthritis & Rheumatism 1986;29:352-7. Ref ID: 74 33. Ford DK, da Roza D, Schulzer M. Lymphocytes from the site of disease but not blood lymphocytes indicate the cause of arthritis. Annals of the Rheumatic Diseases 1985;44:701-10. Ref ID: 75 34. Edmonds J. Reactive arthritis. [Review] [75 refs]. Australian & New Zealand Journal of Medicine 1984;14:81-8. Ref ID: 80 35. Kita E, Nishikawa F, Kamikaidou N, Nakano A, Katsui N, Kashiba S. Mononuclear cell response in the liver of mice infected with hepatotoxigenic Campylobacter jejuni. Journal of Medical Microbiology 1992;37(5):326-331 36. Erlacher L, Wintersberger W, Menschik M, Benke-Studnicka A, Machold K, Stanek G et al. Reactive arthritis: urogenital swab culture is the only useful diagnostic method for the detection of the arthritogenic infection in extra-articularly asymptomatic patients with undifferentiated oligoarthritis. British Journal of Rheumatology 1995;34:838-42. Ref ID: 25 37. Braun J, Tuszewski M, Eggens U, Mertz A, Schauer-Petrowskaja C, Doring et al. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. I. Screening of synovial fluid samples of patients with spondyloarthropathies and other arthritides. Journal of Rheumatology 1997;24:1092-100. Ref ID: 19 38. Braun J, Tuszewski M, Ehlers S, Haberle J, Bollow M, Eggens U et al. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. II. Examination of sacroiliac and knee joint biopsies of patients with spondyloarthropathies and other arthritides. Journal of Rheumatology 1997;24:1101-5. Ref ID: 20 39. Hannu T, Puolakkainen M, Leirisalo-Repo M. Chlamydia pneumoniae as a triggering infection in reactive arthritis. Rheumatology (Oxford) 1999;38:411-4. Ref ID: 9 40. Bengtsson A, Ahlstrand C, Lindstrom FD, Kihlstrom E. Bacteriological findings in patients with Reiter's syndrome (reactive arthritis). Scandinavian Journal of Rheumatology 1983;12:157-60. Ref ID: 94 246 41. Pitkanen T, Pettersson T, Ponka A, Kosunen TU. Clinical and serological studies in patients with Campylobacter fetus ssp. jejuni infection: I. Clinical findings. Infection 1981;9:274-8. Ref ID: 104 42. Kosunen TU, Ponka A, Kauranen O, Martio J, Pitkanen T, Hortling L et al. Arthritis associated with Campylobacter jejuni enteritis. Scandinavian Journal of Rheumatology 1981;10:77-80. 43. Gumpel JM, Martin C, Sanderson PJ. Reactive arthritis associated with campylobacter enteritis. Annals of the Rheumatic Diseases 1981;40:64-5. Ref ID: 108 44. van de Putte LB, Berden JH, BoerbooMS MT, Muller WH, Rasker JJ, Reynvaan- Groendijk A et al. Reactive arthritis after Campylobacter jejuni enteritis. Journal of Rheumatology 1980;7:531-5. Ref ID: 113 45. Stafford L,.Bertouch J. Reactive arthritis and ruptured Achilles tendon [letter]. Annals of the Rheumatic Diseases 1998;57:61. Ref ID: 13 46. Goudswaard J, Sabbe L, te WW. Reactive arthritis as a complication of Campylobacter lari enteritis [letter]. Journal of Infection 1995;31:171. Ref ID: 24 47. Watine J, Martorell J, Bruna T, Gineston JL, Poirier JL, Lamblin G. In vivo pefloxacin-resistant Campylobacter fetus responsible for gastro-intestinal infection and bacteremia associated with arthritis of the hip. Yonsei Medical Journal 1995;36:202-5. Ref ID: 28 48. Simon CH,.Markusse HM. Campylobacter jejuni arthritis in secondary amyloidosis. Clinical Rheumatology 1995;14:214-6. Ref ID: 30 49. Policastro AM. Index of suspicion. Case 3. Campylobacter gastroenteritis with joint pain. Pediatrics in Review 119;15:117. Ref ID: 35 50. Han CD, Lee JW, Chong Y. Pyogenic arthritis of the hip due to Campylobacter fetus- -a case report. Yonsei Medical Journal 1992;33:87-90. Ref ID: 45 51. Pasticci MB, Baratta E, Del Favero A, Gillio A, Baldelli F, Pauluzzi S. Campylobacter jejuni--an unusual cause of infectious arthritis [letter]. Postgraduate Medical Journal 1992;68:151-2. Ref ID: 46 52. Palombi L, Mancinelli S, Marazzi MC, Galeazzi M, Pasquini P, Garpodinoff et al. Antimicrobial antibodies in patients with a non-specific arthritis [letter]. Clinical & Experimental Rheumatology 1989;7:659-60. Ref ID: 60 247 53. Rynes RI, Volastro PS, Bartholomew LE. Exacerbation of B27 positive spondyloarthropathy by enteric infections. Journal of Rheumatology 1984;11:96-7. Ref ID: 82 54. Ebright JR,.Ryan LM. Acute erosive reactive arthritis associated with Campylobacter jejuni-induced colitis. American Journal of Medicine 1984;76:321-3. Ref ID: 84 55. Johnsen K, Ostensen M, Melbye AC, Melby K. HLA-B27-negative arthritis related to Campylobacter jejuni enteritis in three children and two adults. Acta Medica Scandinavica 1983;214:165-8. Ref ID: 91 56. Albert J, Spaeth PJ, Ott H, Buetler R. Symmetrical reactive oligoarthritis after Campylobacter jejuni enteritis--case report and study of the synovial complement. Zeitschrift fur Rheumatologie 1983;42:104-6. Ref ID: 93 57. Bengtsson A, Lindstrom FD, Normann BE. Reactive arthritis after Campylobacter jejuni enteritis. A case report. Scandinavian Journal of Rheumatology 1983;12:181-2. Ref ID: 95 58. Ponka A, Martio J, Kosunen TU. Reiter's syndrome in association with enteritis due to Campylobacter fetus ssp. jejuni. Annals of the Rheumatic Diseases 1981;40:414-5. Ref ID: 105 59. Eastmond CJ, Reid TM, Rennie JA. Reactive arthritis associated with campylobacter enteritis [letter]. Annals of the Rheumatic Diseases 1981;40:431. Ref ID: 106 60. Ponka A, Pitkanen T, Pettersson T, Aittoniemi S, Kosunen TU. Carditis and arthritis associated with Campylobacter jejuni infection. Acta Medica Scandinavica 1980;208:495-6. Ref ID: 111 61. Saari KM,.Kauranen O. Ocular inflammation in Reiter's syndrome associated with Campylobacter jejuni enteritis. American Journal of Ophthalmology 1980;90:572-3. Ref ID: 112 61. Leung FY, Littlejohn GO, Bombardier C. Reiter's syndrome after Campylobacter jejuni enteritis. Arthritis & Rheumatism 1980;23:948-50. Ref ID: 114 62. Kosunen TU, Kauranen O, Martio J, Pitkanen T, Ponka A, Hortling L et al. Reactive arthritis after Campylobacter jejuni enteritis in patients with HLA-B27 [letter]. Lancet 1980;1:1312-3. Ref ID: 115 63. Bekassay AN, Enell H, Schalen C. Severe polyarthritis following Campylobacter enteritis in a 12-year-old boy. Acta Paediatrica Scandinavica 1980;69:269-71. Ref ID: 116 64. Fick RB, Jr., Isturiz R, Cadman EC. Campylobacter fetus septic arthritis: report of a case. Yale Journal of Biology & Medicine 1979;52:339-44. Ref ID: 118 248 65. Berden JH, Muytjens HL, van de Putte LB. Reactive arthritis associated with Campylobacter jejuni enteritis. British Medical Journal 1979;1:380-1. Ref ID: 119 67. Urman JD, Zurier RB, Rothfield NF. Reiter's syndrome associated with Campylobacter fetus infection [letter]. Annals of Internal Medicine 1977;86:444-5. Ref ID: 120 Campylobacter and Reactive Arthritis and Reiter's Disease - science citation index search 1 Smith JL, Palumbo SA, Walls I. Relationship between foodborne bacterial pathogens and the reactive arthritides. Journal of Food Safety 1993;13:209-36. 2 Smith JL. Arthritis and foodborne bacteria. Journal of Food Protection 1994;57:935-41. 3 Smith JL. Arthritis, Guillain-Barre-Syndrome, and other sequelae of Campylobacter jejuni enteritis. Journal of Food Protection 1995;58:1153-70. CAMPYLOBACTER AND GUILLAIN-BARRE SYNDROME Campylobacter and Guillain-Barre Syndrome – medline search 1. Plaut AG. Clinical pathology of foodborne diseases: notes on the patient with foodborne gastrointestinal illness. [Review] [18 refs]. Journal of Food Protection 2000;63:822-6. Ref ID: 3 2. Asbury AK. New concepts of Guillain-Barre syndrome. [Review] [78 refs]. Journal of Child Neurology 2000;15:183-91. Ref ID: 10 3. Hughes RA, Hadden RD, Gregson NA, Smith KJ. Pathogenesis of Guillain-Barre syndrome. [Review] [296 refs]. Journal of Neuroimmunology 1999;100:74-97. Ref ID: 22 4. Willison HJ,.O'Hanlon GM. The immunopathogenesis of Miller Fisher syndrome. [Review] [85 refs]. Journal of Neuroimmunology 1999;100:3-12. Ref ID: 23 5. Toyka KV. Eighty three years of the Guillain-Barre syndrome: clinical and immunopathologic aspects, current and future treatments. [Review] [59 refs]. Revue Neurologique 1999;155:849-56. Ref ID: 28 6. Yuki N. Pathogenesis of Guillain-Barre and Miller Fisher syndromes subsequent to Campylobacter jejuni enteritis. [Review] [66 refs]. Japanese Journal of Infectious Diseases 1999;52:99-105. Ref ID: 53 7. Trojaborg W. Acute and chronic neuropathies: new aspects of Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy, an overview and an update. [Review] [117 refs]. Electroencephalography & Clinical Neurophysiology 1998;107:303-16. Ref ID: 62 249 8. Hahn AF. Guillain-Barre syndrome. [Review] [74 refs]. Lancet 1998;352:635-41. Ref ID: 69 9. Nachamkin I, Allos BM, Ho T. Campylobacter species and Guillain-Barre syndrome. [Review] [186 refs]. Clinical Microbiology Reviews 1998;11:555-67. 10. Fredman P. The role of antiglycolipid antibodies in neurological disorders. [Review] [51 refs]. Annals of the New York Academy of Sciences 1998;845:341-52. Ref ID: 83 11. Altekruse SF, Swerdlow DL, Stern NJ. Microbial food borne pathogens. Campylobacter jejuni. [Review] [68 refs]. Veterinary Clinics of North America - Food Animal Practice 1998;14:31-40. Ref ID: 90 12. Allos BM. Campylobacter jejuni infection as a cause of the Guillain-Barre syndrome. [Review] [102 refs]. Infectious Disease Clinics of North America 1998;12:173-84. Ref ID: 91 12. McDowell RM,.McElvaine MD. Long-term sequelae to foodborne disease. [Review] [21 refs]. Revue Scientifique et Technique 1997;16:337-41. Ref ID: 96 14. Hughes RA,.Rees JH. Clinical and epidemiologic features of Guillain-Barre syndrome. [Review] [84 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S92-S98. Ref ID: 100 15. van der Meche FG, Visser LH, Jacobs BC, Endtz HP, Meulstee J, van D et al. Guillain-Barre syndrome: multifactorial mechanisms versus defined subgroups. [Review] [20 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S99-102. Ref ID: 101 16. Blaser MJ. Epidemiologic and clinical features of Campylobacter jejuni infections. [Review] [25 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S103-S105. Ref ID: 102 17. Allos BM. Association between Campylobacter infection and Guillain-Barre syndrome. [Review] [30 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S125-S128. Ref ID: 105 18. van der Meche FG. The Guillain-Barre syndrome; pathogenesis and treatment. [Review] [24 refs]. Revue Neurologique 1996;152:355-8. Ref ID: 143 19. van der Meche FG,.van Doorn PA. Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy: immune mechanisms and update on current therapies. [Review] [167 refs]. Annals of Neurology 1995;37 Suppl 1:S14-S31. Ref ID: 159 20. Jones HR, Jr. Guillain-Barre syndrome in children. [Review] [47 refs]. Current Opinion in Pediatrics 1995;7:663-8. Ref ID: 162 250 21. Hartung HP, Pollard JD, Harvey GK, Toyka KV. Immunopathogenesis and treatment of the Guillain-Barre syndrome--Part II. [Review] [120 refs]. Muscle & Nerve 1995; 18: 154 64. Ref ID: 184 22. Allos BM,.Blaser MJ. Campylobacter jejuni infection and the Guillain-Barre syndrome: mechanisms and implications. [Review] [55 refs]. Zentralblatt fur Bakteriologie 1994;281:544-8. Ref ID: 188 23. Hughes RA,.Rees JH. Guillain-Barre syndrome [see comments]. [Review] [80 refs]. Current Opinion in Neurology 1994;7:386-92. Ref ID: 189 24. Peterson MC. Clinical aspects of Campylobacter jejuni infections in adults [see comments]. [Review] [71 refs]. Western Journal of Medicine 1994;161:148-52. Ref ID: 192 25. Rees JH, Gregson NA, Griffiths PL, Hughes RA. Campylobacter jejuni and Guillain- Barre syndrome. [Review] [82 refs]. Quarterly Journal of Medicine 1993;86:623-34. Ref ID: 207 26. Mishu B,.Blaser MJ. Role of infection due to Campylobacter jejuni in the initiation of Guillain-Barre syndrome. [Review] [58 refs]. Clinical Infectious Diseases 1993;17:104-8. Ref ID: 209 27. Feasby TE. Inflammatory-demyelinating polyneuropathies. [Review] [94 refs]. Neurologic Clinics 1992; 10:651-70. Ref ID: 220 28. Sovilla JY, Regli F, Francioli PB. Guillain-Barre syndrome following Campylobacter jejuni enteritis. Report of three cases and review of the literature. [Review] [25 refs]. Archives of Internal Medicine 1988;148:739-41. Ref ID: 241 29. Van Koningsveld R, van Doorn PA, Schmitz PI, Ang CW, van der Meche FG. Mild forms of Guillain-Barre syndrome in an epidemiologic survey in The Netherlands. Neurology 2000;54:620-5. Ref ID: 16 30. Koga M, Yuki N, Takahashi M, Saito K, Hirata K. Are Campylobacter curvus and Campylobacter upsaliensis antecedent infectious agents in Guillain-Barre and Fisher's syndromes? Journal of the Neurological Sciences 1999;163:53-7. Ref ID: 47 31. Jacobs BC, Rothbarth PH, van der Meche FG, Herbrink P, Schmitz PI, de et al. The spectrum of antecedent infections in Guillain-Barre syndrome: a case-control study. Neurology 1998;51:1110-5. Ref ID: 68 32. Hao Q, Saida T, Kuroki S, Nishimura M, Nukina M, Obayashi H et al. Antibodies to gangliosides and galactocerebroside in patients with Guillain-Barre syndrome with preceding Campylobacter jejuni and other identified infections. Journal of Neuroimmunology 1998;81:116-26. Ref ID: 92 251 33. Koga M, Yuki N, Takahashi M, Saito K, Hirata K. Close association of IgA anti ganglioside antibodies with antecedent Campylobacter jejuni infection in Guillain-Barre and Fisher's syndromes. Journal of Neuroimmunology 1998;81:138-43. Ref ID: 93 34. Saida T, Kuroki S, Hao Q, Nishimura M, Nukina M, Obayashi H. Campylobacter jejuni isolates from Japanese patients with Guillain-Barre syndrome. Journal of Infectious Diseases 1997;176 Suppl 2:S129-S134. Ref ID: 106 35. Hariharan H, Naseema K, Kumaran C, Shanmugam J, Nair MD, Radhakrishnan et al. Detection of Campylobacter jejuni/C.coli infection in patients with Guillain-Barre syndrome by serology and culture. New Microbiologica 1996;19:267-71. Ref ID: 146 36. Jacobs BC, van Doorn PA, Schmitz PI, Tio-Gillen AP, Herbrink P, Visser L et al. Campylobacter jejuni infections and anti-GM1 antibodies in Guillain-Barre syndrome. Annals of Neurology 1996;40:181-7. Ref ID: 152 37. Rees JH, Soudain SE, Gregson NA, Hughes RA. Campylobacter jejuni infection and Guillain-Barre syndrome [see comments]. New England Journal of Medicine 1995;333:1374- 9. Ref ID: 170 38. Tang J, Yuan J, Hao H. GM1 antibody in Guillain-Barre syndrome after Campylobacter jejuni infection. Chinese Medical Journal 1995;108:262-4. Ref ID: 181 39. Vriesendorp FJ, Mishu B, Blaser MJ, Koski CL. Serum antibodies to GM1, GD1b, peripheral nerve myelin, and Campylobacter jejuni in patients with Guillain-Barre syndrome and controls: correlation and prognosis [see comments]. Annals of Neurology 1993;34:130-5. Ref ID: 211 40. Mishu B, Ilyas AA, Koski CL, Vriesendorp F, Cook SD, Mithen FA et al. Serologic evidence of previous Campylobacter jejuni infection in patients with the Guillain-Barre syndrome. Annals of Internal Medicine 1993;118:947-53. Ref ID: 214 41. Kuroki S, Saida T, Nukina M, Haruta T, Yoshioka M, Kobayashi Y et al. Campylobacter jejuni strains from patients with Guillain-Barre syndrome belong mostly to Penner serogroup 19 and contain beta-N-acetylglucosamine residues. Annals of Neurology 1993;33:243-7. Ref ID: 215 42. Gruenewald R, Ropper AH, Lior H, Chan J, Lee R, Molinaro VS. Serologic evidence of Campylobacter jejuni/coli enteritis in patients with Guillain-Barre syndrome. Archives of Neurology 1991;48:1080-2. Ref ID: 229 43. Kaldor J,.Speed BR. Guillain-Barre syndrome and Campylobacter jejuni: a serological study. British Medical Journal Clinical Research Ed 1984;. 288:1867-70. Ref ID: 248 252 44. Endtz HP, Ang CW, van Den BN, Duim B, Rigter A, Price LJ et al. Molecular characterization of Campylobacter jejuni from patients with Guillain-Barre and Miller Fisher syndromes. Journal of Clinical Microbiology 2000;38:2297-301. Ref ID: 4 45. McCarthy N, Andersson Y, Jormanainen V, Gustavsson O, Giesecke J. The risk of Guillain-Barre syndrome following infection with Campylobacter jejuni. Epidemiology & Infection 1999;122:15-7. Ref ID: 50 46. Roman GC. Epidemic neuropathy in Cuba: a public health problem related to the Cuban Democracy Act of the United States. [Review] [31 refs]. Neuroepidemiology 1998;17:111-5. Ref ID: 78 47. Sacks JJ, Lieb S, Baldy LM, Berta S, Patton CM, White MC et al. Epidemic campylobacteriosis associated with a community water supply. American Journal of Public Health 1986;76:424-8. Ref ID: 245 48. Linton D, Gilbert M, Hitchen PG, Dell A, Morris HR, Wakarchuk WW et al. Phase variation of a beta-1,3 galactosyltransferase involved in generation of the ganglioside GM1 like lipo-oligosaccharide of Campylobacter jejuni. Molecular Microbiology 2000;37:501-14. Ref ID: 1 49. Yuki N. Anti-ganglioside antibody and neuropathy: review of our research. [Review] [117 refs]. Journal of the Peripheral Nervous System 1998;3:3-18. Ref ID: 2 50. Misawa N, Allos BM, Blaser MJ. Differentiation of Campylobacter jejuni serotype O19 strains from non-O19 strains by PCR [published erratum appears in J Clin Microbiol 2000 Jan;38(1):474] [see comments]. Journal of Clinical Microbiology 1998;36:3567-73. Ref ID: 5 51. Bersudsky M, Rosenberg P, Rudensky B, Wirguin I. Lipopolysaccharides of a Campylobacter coli isolate from a patient with Guillain-Barre syndrome display ganglioside mimicry. Neuromuscular Disorders 2000;10:182-6. Ref ID: 11 52. Yuki N, Ang CW, Koga M, Jacobs BC, van Doorn PA, Hirata K et al. Clinical features and response to treatment in Guillain-Barre syndrome associated with antibodies to GM1b ganglioside. Annals of Neurology 2000;47:314-21. Ref ID: 12 53. Ang CW, Endtz HP, Jacobs BC, Laman JD, de Klerk MA, van der Meche FG et al. Campylobacter jejuni lipopolysaccharides from Guillain-Barre syndrome patients induce IgG anti-GM1 antibodies in rabbits. Journal of Neuroimmunology 2000;104:133-8. Ref ID: 13 54. Linton D, Karlyshev AV, Hitchen PG, Morris HR, Dell A, Gregson NA et al. Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide. Molecular Microbiology 2000;35:1120-34. Ref ID: 15 253 55. Karlyshev AV, Linton D, Gregson NA, Lastovica AJ, Wren BW. Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity. Molecular Microbiology 2000;35:529-41. Ref ID: 17 56. Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J et al. Monoclonal antibodies raised against Guillain-Barre syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations [published erratum appears in J Clin Invest 1999 Dec;104(12):1771]. Journal of Clinical Investigation 1999;104:697-708. Ref ID: 18 57. Wassenaar TM, Fry BN, Lastovica AJ, Wagenaar JA, Coloe PJ, Duim B. Genetic characterization of Campylobacter jejuni O:41 isolates in relation with Guillain-Barre syndrome. Journal of Clinical Microbiology 2000;38:874-6. Ref ID: 19 58. Gilbert M, Brisson JR, Karwaski MF, Michniewicz J, Cunningham AM, Wu Y et al. Biosynthesis of ganglioside mimics in Campylobacter jejuni OH4384. Identification of the glycosyltransferase genes, enzymatic synthesis of model compounds, and characterization of nanomole amounts by 600-mhz (1)h and (13)c NMR analysis. Journal of Biological Chemistry 2000;275:3896-906. Ref ID: 20 59. Parkhill J, Wren BW, Mungall K, Ketley JM, Churcher C, Basham D et al. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 2000;403:665-8. Ref ID: 21 60. Kaida K, Kusunoki S, Kamakura K, Motoyoshi K, Kanazawa I. Guillain-Barre syndrome with antibody to a ganglioside, N-acetylgalactosaminyl GD1a. Brain 2000;123:116-24. Ref ID: 24 61. Ang CW, Yuki N, Jacobs BC, Koga M, van Doorn PA, Schmitz PI et al. Rapidly progressive, predominantly motor Guillain-Barre syndrome with anti-GalNAc-GD1a antibodies. Neurology 1999;53:2122-7. Ref ID: 29 62. Yako K, Kusunoki S, Kanazawa I. Serum antibody against a peripheral nerve myelin ganglioside, LM1, in Guillain-Barre syndrome [see comments]. Journal of the Neurological Sciences 1999;168:85-9. Ref ID: 33 63. Carpo M, Pedotti R, Allaria S, Lolli F, Mata S, Cavaletti G et al. Clinical presentation and outcome of Guillain-Barre and related syndromes in relation to anti-ganglioside antibodies [see comments]. Journal of the Neurological Sciences 1999;168:78-84. Ref ID: 34 64. Yuki N, Kuwabara S, Koga M, Hirata K. Acute motor axonal neuropathy and acute motor-sensory axonal neuropathy share a common immunological profile. Journal of the Neurological Sciences 1999;168:121-6. Ref ID: 36 254 65. Yuki N, Ho TW, Tagawa Y, Koga M, Li CY, Hirata K et al. Autoantibodies to GM1b and GalNAc-GD1a: relationship to Campylobacter jejuni infection and acute motor axonal neuropathy in China. Journal of the Neurological Sciences 1999;164:134-8. Ref ID: 38 66. Kuwabara S, Ogawara K, Koga M, Mori M, Hattori T, Yuki N. Hyperreflexia in Guillain-Barre syndrome: relation with acute motor axonal neuropathy and anti-GM1 antibody. Journal of Neurology, Neurosurgery & Psychiatry 1999;67:180-4. Ref ID: 40 67. Fujimoto S,.Fujita M. Serum antibody level against GroEL type heat-shock protein of Campylobacter jejuni in patients with Guillain-Barre syndrome. Microbiology & Immunology 1999;43:241-4. Ref ID: 42 68. Prendergast MM, Willison HJ, Moran AP. Human monoclonal immunoglobulin M antibodies to ganglioside GM1 show diverse cross-reactivities with lipopolysaccharides of Campylobacter jejuni strains associated with Guillain-Barre syndrome. Infection & Immunity 1999;67:3698-701. Ref ID: 44 69. Hao Q, Saida T, Yoshino H, Kuroki S, Nukina M, Saida K. Anti-GalNAc-GD1a antibody-associated Guillain-Barre syndrome with a predominantly distal weakness without cranial nerve impairment and sensory disturbance. Annals of Neurology 1999;45:758-68. Ref ID: 45 70. Koga M, Yuki N, Hirata K. Subclass distribution and the secretory component of serum IgA anti-ganglioside antibodies in Guillain-Barre syndrome after Campylobacter jejuni enteritis. Journal of Neuroimmunology 1999;96:245-50. Ref ID: 46 71. Nachamkin I, Ung H, Moran AP, Yoo D, Prendergast MM, Nicholson MA et al. Ganglioside GM1 mimicry in Campylobacter strains from sporadic infections in the United States [published erratum appears in J Infect Dis 1999 Jun;179(6):1593]. Journal of Infectious Diseases 1999;179:1183-9. Ref ID: 48 72. Schwerer B, Neisser A, Bernheimer H. Distinct immunoglobulin class and immunoglobulin G subclass patterns against ganglioside GQ1b in Miller Fisher syndrome following different types of infection. Infection & Immunity 1999;67:2414-20. Ref ID: 49 73. Ho TW, Willison HJ, Nachamkin I, Li CY, Veitch J, Ung H et al. Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-Barre syndrome. Annals of Neurology 1999;45:168-73. Ref ID: 51 74. Thies FL, Karch H, Hartung HP, Giegerich G. Cloning and expression of the dnaK gene of Campylobacter jejuni and antigenicity of heat shock protein 70. Infection & Immunity 1999;67:1194-200. Ref ID: 52 255 75. Goffette S, Jeanjean A, Pierret F, Peeters A, Sindic CJ. Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barre syndromes. Acta Neurologica Belgica 1998;98:322-6. Ref ID: 56 76. Klena JD, Gray SA, Konkel ME. Cloning, sequencing, and characterization of the lipopolysaccharide biosynthetic enzyme heptosyltransferase I gene (waaC) from Campylobacter jejuni and Campylobacter coli. Gene 1998;222:177-85. Ref ID: 63 77. Ma JJ, Nishimura M, Mine H, Kuroki S, Nukina M, Ohta M et al. Genetic contribution of the tumor necrosis factor region in Guillain-Barre syndrome. Annals of Neurology 1998;44:815-8. Ref ID: 66 78. Ma JJ, Nishimura M, Mine H, Kuroki S, Nukina M, Ohta M et al. HLA and T-cell receptor gene polymorphisms in Guillain-Barre syndrome. Neurology 1998;51:379-84. Ref ID: 76 79. Sheikh KA, Nachamkin I, Ho TW, Willison HJ, Veitch J, Ung H et al. Campylobacter jejuni lipopolysaccharides in Guillain-Barre syndrome: molecular mimicry and host susceptibility. Neurology 1998;51:371-8. Ref ID: 77 80. Allos BM, Lippy FT, Carlsen A, Washburn RG, Blaser MJ. Campylobacter jejuni strains from patients with Guillain-Barre syndrome. Emerging Infectious Diseases 1998;4:263-8. Ref ID: 79 81. Sheikh KA, Ho TW, Nachamkin I, Li CY, Cornblath DR, Asbury AK et al. Molecular mimicry in Guillain-Barre syndrome. Annals of the New York Academy of Sciences 1998;845:307-21. Ref ID: 81 82. Yuki N,.Miyatake T. Guillain-Barre syndrome and Fisher's syndrome following Campylobacter jejuni infection. Annals of the New York Academy of Sciences 1998; 845: 330-40. Ref ID: 82 83. Gatterbauer B, Neisser A, Bernheimer H, Schwerer B. Antiglycosphingolipid immune responses in neurology. The Vienna experience with isotypes, subclasses, and disease. Annals of the New York Academy of Sciences 1998;845:353-62. Ref ID: 84 84. Prendergast MM, Lastovica AJ, Moran AP. Lipopolysaccharides from Campylobacter jejuni O:41 strains associated with Guillain-Barre syndrome exhibit mimicry of GM1 ganglioside. Infection & Immunity 1998;66:3649-55. Ref ID: 85 85. Koga M, Yuki N, Kashiwase K, Tadokoro K, Juji T, Hirata K. Guillain-Barre and Fisher's syndromes subsequent to Campylobacter jejuni enteritis are associated with HLA- B54 and Cw1 independent of anti-ganglioside antibodies. Journal of Neuroimmunology 1998;88:62-6. Ref ID: 86 256 86. Ohtsuka K, Nakamura Y, Hashimoto M, Tagawa Y, Takahashi M, Saito K et al. Fisher syndrome associated with IgG anti-GQ1b antibody following infection by a specific serotype of Campylobacter jejuni. Ophthalmology 1998;105:1281-5. Ref ID: 88 87. Guerry P. Nonlipopolysaccharide surface antigens of Campylobacter species. [Review] [31 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S122-S124. Ref ID: 104 88. Yuki N. Molecular mimicry between gangliosides and lipopolysaccharides of Campylobacter jejuni isolated from patients with Guillain-Barre syndrome and Miller Fisher syndrome [see comments]. [Review] [27 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S150-S153. Ref ID: 108 89. Rostami AM. P2-reactive T cells in inflammatory demyelination of the peripheral nerve. [Review] [33 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S160-S163. Ref ID: 109 90. Vriesendorp FJ. Insights into Campylobacter jejuni-induced Guillain-Barre syndrome from the Lewis rat model of experimental allergic neuritis. [Review] [29 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S164-S168. Ref ID: 110 91. Koski CL. Mechanisms of Schwann cell damage in inflammatory neuropathy. [Review] [28 refs]. Journal of Infectious Diseases 1997;176 Suppl 2:S169-S172. Ref ID: 111 92. Monos DS, Papaioakim M, Ho TW, Li CY, McKhann GM. Differential distribution of HLA alleles in two forms of Guillain-Barre syndrome. Journal of Infectious Diseases 1997;176 Suppl 2:S180-S182. Ref ID: 112 93. Jacobs BC, O'Hanlon GM, Breedland EG, Veitch J, van Doorn PA, Willison et al. Human IgM paraproteins demonstrate shared reactivity between Campylobacter jejuni lipopolysaccharides and human peripheral nerve disialylated gangliosides. Journal of Neuroimmunology 1997;80:23-30. Ref ID: 117 94. Jacobs BC, Endtz HP, van der Meche FG, Hazenberg MP, de Klerk MA, van et al. Humoral immune response against Campylobacter jejuni lipopolysaccharides in Guillain- Barre and Miller Fisher syndrome. Journal of Neuroimmunology 1997;79:62-8. Ref ID: 118 95. Fujimoto S, Allos BM, Misawa N, Patton CM, Blaser MJ. Restriction fragment length polymorphism analysis and random amplified polymorphic DNA analysis of Campylobacter jejuni strains isolated from patients with Guillain-Barre syndrome. Journal of Infectious Diseases 1997;176:1105-8. Ref ID: 119 96. Sindern E, Oreja-Guevara C, Raulf-HeiMSoth M, Baur X, Malin JP. A longitudinal study of circulating lymphocyte subsets in the peripheral blood during the acute stage of Guillain-Barre syndrome. Journal of the Neurological Sciences 1997;151:29-34. Ref ID: 120 257 97. Ben Smith A, Goodall JC, Gaston JS, Winer JB. Stimulation of peripheral blood lymphocytes with Campylobacter jejuni generates a gammadelta T cell response in patients with Guillain-Barresyndrome. Clinical & Experimental Immunology 1997;109:121-6. Ref ID: 122 98. Yuki N, Takahashi M, Tagawa Y, Kashiwase K, Tadokoro K, Saito K. Association of Campylobacter jejuni serotype with antiganglioside antibody in Guillain-Barre syndrome and Fisher's syndrome. Annals of Neurology 1997;42:28-33. Ref ID: 123 99. Yuki N, Tagawa Y, Irie F, Hirabayashi Y, Handa S. Close association of Guillain- Barre syndrome with antibodies to minor monosialogangliosides GM1b and GM1 alpha. Journal of Neuroimmunology 1997;74:30-4. Ref ID: 129 100. Ho TW, Hsieh ST, Nachamkin I, Willison HJ, Sheikh K, Kiehlbauch J et al. Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection [see comments]. Neurology 1997;48:71724. Ref ID: 130 101. Gregson NA, Rees JH, Hughes RA. Reactivity of serum IgG anti-GM1 ganglioside antibodies with the lipopolysaccharide fractions of Campylobacter jejuni isolates from patients with Guillain-Barre syndrome (GBS). Journal of Neuroimmunology 1997;73:28-36. Ref ID: 131 102. Melendez-Vasquez C, Redford J, Choudhary PP, Gray IA, Maitland P, Gregson NA et al. Immunological investigation of chronic inflammatory demyelinating polyradiculoneuropathy. Journal of Neuroimmunology 1997;73:124-34. 103. Jacobs BC, Hazenberg MP, van Doorn PA, Endtz HP, van der Meche FG. Cross reactive antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in patients with Guillain-Barre or Miller Fisher syndrome. Journal of Infectious Diseases 1997;175:729-33. Ref ID: 133 104. Bech E, Orntoft TF, Andersen LP, Skinhoj P, Jakobsen J. IgM anti-GM1 antibodies in the Guillain-Barre syndrome: a serological predictor of the clinical course. Journal of Neuroimmunology 1997;72:59-66. Ref ID: 134 105. Moran AP, Prendergast MM, Appelmelk BJ. Molecular mimicry of host structures by bacterial lipopolysaccharides and its contribution to disease. [Review] [94 refs]. FEMS Immunology & Medical Microbiology 1996;16:105-15. Ref ID: 137 106. Saida K. The immunopathology of Guillain-Barre syndrome. [Review] [37 refs]. Current Opinion in Neurology 1996;9:329-33. Ref ID: 140 107. Yuki N, Taki T, Handa S. Antibody to GalNAc-GD1a and GalNAc-GM1b in Guillain-Barre syndrome subsequent to Campylobacter jejuni enteritis. Journal of Neuroimmunology 1996;71:155-61. Ref ID: 141 258 108. Ben Smith A, Gaston JS, Barber PC, Winer JB. Isolation and characterisation of T lymphocytes from sural nerve biopsies in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy. Journal of Neurology, Neurosurgery & Psychiatry 1996;61:362-8. Ref ID: 142 109. Griffin JW, Li CY, Macko C, Ho TW, Hsieh ST, Xue P et al. Early nodal changes in the acute motor axonal neuropathy pattern of the Guillain-Barre syndrome. Journal of Neurocytology 1996;25:33-51. Ref ID: 145 110. Deisenhammer F, Keir G, Pfausler B, Thompson EJ. Affinity of anti-GM1 antibodies in Guillain-Barre syndrome patients. Journal of Neuroimmunology 1996;66:85-93. Ref ID: 148 111. Yuki N, Tagawa Y, Handa S. Autoantibodies to peripheral nerve glycosphingolipids SPG, SLPG, and SGPG in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy. Journal of Neuroimmunology 1996;70:1-6. Ref ID: 150 112. Hafer-Macko C, Hsieh ST, Li CY, Ho TW, Sheikh K, Cornblath DR et al. Acute motor axonal neuropathy: an antibody-mediated attack on axolemma. Annals of Neurology 1996;40:635-44. Ref ID: 151 113. Li CY, Xue P, Tian WQ, Liu RC, Yang C. Experimental Campylobacter jejuni infection in the chicken: an animal model of axonal Guillain-Barre syndrome. Journal of Neurology, Neurosurgery & Psychiatry 1996;61:279-84. Ref ID: 153 114. Salloway S, Mermel LA, Seamans M, Aspinall GO, Nam Shin JE, Kurjanczyk et al. Miller-Fisher syndrome associated with Campylobacter jejuni bearing lipopolysaccharide molecules that mimic human ganglioside GD3. Infection & Immunity 1996;64:2945-9. Ref ID: 154 115. Rees JH, Vaughan RW, Kondeatis E, Hughes RA. HLA-class II alleles in Guillain- Barre syndrome and Miller Fisher syndrome and their association with preceding Campylobacter jejuni infection. Journal of Neuroimmunology 1995;62:53-7. Ref ID: 167 116. Rees JH, Gregson NA, Hughes RA. Anti-ganglioside GM1 antibodies in Guillain -Barre syndrome and their relationship to Campylobacter jejuni infection. Annals of Neurology 1995;38:809-16. Ref ID: 168 117. Oomes PG, Jacobs BC, Hazenberg MP, Banffer JR, van der Meche FG. Anti-GM1 IgG antibodies and Campylobacter bacteria in Guillain-Barre syndrome: evidence of molecular mimicry. Annals of Neurology 1995;38:170-5. Ref ID: 173 118. Yuki N, Handa S, Tai T, Takahashi M, Saito K, Tsujino Y et al. Ganglioside-like epitopes of lipopolysaccharides from Campylobacter jejuni (PEN 19) in three isolates from patients with Guillain-Barre syndrome. Journal of the Neurological Sciences 1995;130:112-6. Ref ID: 174 259 119. Yuki N, Ichihashi Y, Taki T. Subclass of IgG antibody to GM1 epitope-bearing lipopolysaccharide of Campylobacter jejuni in patients with Guillain-Barre syndrome. Journal of Neuroimmunology 1995;60:161-4. Ref ID: 175 120. Ogino M, Orazio N, Latov N. IgG anti-GM1 antibodies from patients with acute motor neuropathy are predominantly of the IgG1 and IgG3 subclasses. Journal of Neuroimmunology 1995;58:77-80. Ref ID: 183 121. Hartung HP, Pollard JD, Harvey GK, Toyka KV. Immunopathogenesis and treatment of the Guillain-Barre syndrome--Part I. [Review] [234 refs]. Muscle & Nerve 1995; 18: 137-53. Ref ID: 185 122. von Wulffen H, Hartard C, Scharein E. Seroreactivity to Campylobacter jejuni and gangliosides in patients with Guillain-Barre syndrome [see comments]. Journal of Infectious Diseases 1994;170:828-33. Ref ID: 193 123. Seiser A, Potzl G, Safoschnik G, Pichler S, Bernheimer H, Schwerer B. GM 1 antibodies in Guillain-Barre syndrome: isotypes, course and clinical outcome. Wiener Klinische Wochenschrift 1994;106:159-63. Ref ID: 196 124. Yuki N. Pathogenesis of axonal Guillain-Barre syndrome: hypothesis. Muscle & Nerve 1994;17:680-2. Ref ID: 197 125. Aspinall GO, Fujimoto S, McDonald AG, Pang H, Kurjanczyk LA, Penner JL. Lipopolysaccharides from Campylobacter jejuni associated with Guillain-Barre syndrome patients mimic human gangliosides in structure. Infection & Immunity 1994;62:2122-5. Ref ID: 198 126. Kornberg AJ, Pestronk A, Bieser K, Ho TW, McKhann GM, Wu HS et al. The clinical correlates of high-titer IgG anti-GM1 antibodies [see comments]. Annals of Neurology 1994;35:234-7. Ref ID: 201 127. Aspinall GO, McDonald AG, Pang H. Lipopolysaccharides of Campylobacter jejuni serotype O:19: structures of O antigen chains from the serostrain and two bacterial isolates from patients with the Guillain-Barre syndrome. Biochemistry 1994;33:250-5. Ref ID: 203 128. Yuki N, Taki T, Inagaki F, Kasama T, Takahashi M, Saito K et al. A bacterium lipopolysaccharide that elicits Guillain-Barre syndrome has a GM1 ganglioside-like structure. Journal of Experimental Medicine 1993;178:1771-5. Ref ID: 208 129. Enders U, Karch H, Toyka KV, Michels M, Zielasek J, Pette M et al. The spectrum of immune responses to Campylobacter jejuni and glycoconjugates in Guillain-Barre syndrome and in other neuroimmunological disorders [see comments]. Annals of Neurology 1993;34:136-44. Ref ID: 210 260 130. Gregson NA, Koblar S, Hughes RA. Antibodies to gangliosides in Guillain-Barre syndrome: specificity and relationship to clinical features [see comments]. Quarterly Journal of Medicine 1993;86:111-7. Ref ID: 216 131. Khalili-Shirazi A, Hughes RA, Brostoff SW, Linington C, Gregson N. T cell responses to myelin proteins in Guillain-Barre syndrome. Journal of the Neurological Sciences 1992;111:200-3. Ref ID: 218 132. Kita E, Nishikawa F, Kamikaidou N, Nakano A, Katsui N, Kashiba S. Mononuclear cell response in the liver of mice infected with hepatotoxigenic Campylobacter jejuni. Journal of Medical Microbiology 1992;37:326-31. Ref ID: 219 133. Nobile-Orazio E, Carpo M, Meucci N, Grassi MP, Capitani E, Sciacco M et al. Guillain-Barre syndrome associated with high titers of anti-GM1 antibodies. Journal of the Neurological Sciences 1992;109:200-6. Ref ID: 224 134. Oomes PG, van der Meche FG, Markus-Silvis L, Meulstee J, Kleyweg RP. In vivo effects of sera from Guillain-Barre subgroups: an electrophysiological and histological study on rat nerves. Muscle & Nerve 1991;14:1013-20. Ref ID: 227 135. Walsh FS, Cronin M, Koblar S, Doherty P, Winer J, Leon A et al. Association between glycoconjugate antibodies and Campylobacter infection in patients with Guillain- Barre syndrome. Journal of Neuroimmunology 1991;34:43-51. Ref ID: 230 136. Frampton G, Winer JB, Cameron JS, Hughes RA. Severe Guillain-Barre syndrome: an association with IgA anti-cardiolipin antibody in a series of 92 patients. Journal of Neuroimmunology 1988;19:133-9. Ref ID: 238 137. Speed BR, Kaldor J, Watson J, Newton-John H, Tee W, Noonan D et al. Campylobacter jejuni/Campylobacter coli-associated Guillain-Barre syndrome. Immunoblot confirmation of the serological response. Medical Journal of Australia 1987;147:13-6. Ref ID: 243 138. Guarino M, Casmiro M, D'Alessandro R. Campylobacter jejuni infection and Guillain-Barre syndrome: a case-control study. Emilia-Romagna Study Group on Clinical and Epidemiological problems in neurology. Neuroepidemiology 1998;17:296-302. Ref ID: 60 139. Yuan JM, Tang J, Chen QT, Xiao L, Hao HJ, Jia ZD et al. Guillain-Barre syndrome and Campylobacter jejuni infection. A study on the etiological characteristics of Guillain- Barre syndrome in China. Chinese Medical Journal 1993;106:845-7. Ref ID: 205 140. Boucquey D, Sindic CJ, Lamy M, Delmee M, Tomasi JP, Laterre EC. Clinical and serological studies in a series of 45 patients with Guillain-Barre syndrome. Journal of the Neurological Sciences 1991;104:56-63. Ref ID: 228 261 141. Ropper AH. Campylobacter diarrhea and Guillain-Barre syndrome. Archives of Neurology 1988;45:655-6. Ref ID: 240 142. Chiba S, Sugiyama T, Matsumoto H, Hisano K, Awakawa T, Hiura K et al. Antibodies against Helicobacter pylori were detected in the cerebrospinal fluid obtained from patients with Guillain-Barre syndrome. Annals of Neurology 1998;44:686-8. Ref ID: 67 143. Nishimura M, Nukina M, Kuroki S, Obayashi H, Ohta M, Ma JJ et al. Characterization of Campylobacter jejuni isolates from patients with Guillain-Barre syndrome. Journal of the Neurological Sciences 1997;153:91-9. Ref ID: 97 144. Lastovica AJ, Goddard EA, Argent AC. Guillain-Barre syndrome in South Africa associated with Campylobacter jejuni O:41 strains. Journal of Infectious Diseases 1997;176 Suppl 2:S139-S143. Ref ID: 107 145. Goddard EA, Lastovica AJ, Argent AC. Campylobacter 0:41 isolation in Guillain- Barre syndrome. Archives of Disease in Childhood 1997;76:526-8. Ref ID: 125 146. Griffin JW, Li CY, Ho TW, Tian M, Gao CY, Xue P et al. Pathology of the motor sensory axonal Guillain-Barre syndrome [see comments]. Annals of Neurology 1996; 39: 17-28. Ref ID: 158 147. Vriesendorp FJ, Triggs WJ, Mayer RF, Koski CL. Electrophysiological studies in Guillain-Barre syndrome: correlation with antibodies to GM1, GD1B and Campylobacter jejuni. Journal of Neurology 1995;242:460-5. Ref ID: 171 148. Visser LH, van der Meche FG, van Doorn PA, Meulstee J, Jacobs BC, Oomes et al. Guillain-Barre syndrome without sensory loss (acute motor neuropathy). A subgroup with specific clinical, electrodiagnostic and laboratory features. Dutch Guillain-Barre Study Group. Brain 1995;118:841-7. Ref ID: 172 149. Ho TW, Mishu B, Li CY, Gao CY, Cornblath DR, Griffin JW et al. Guillain-Barre syndrome in northern China. Relationship to Campylobacter jejuni infection and anti glycolipid antibodies. Brain 1995;118:597-605. Ref ID: 177 150. Satoh J, Okada K, Kishi T, Nagayama S, Kuroda Y. Cramping pain and prolonged elevation of serum creatine kinase levels in a patient with Guillain-Barre syndrome following Campylobacter jejuni enteritis. European Journal of Neurology 2000;7:107-9. Ref ID: 9 151. Neisser A, Schwerer B, Bernheimer H, Moran AP. Ganglioside-induced antiganglioside antibodies from a neuropathy patient cross-react with lipopolysaccharides of Campylobacter jejuni associated with Guillain-Barre syndrome. Journal of Neuroimmunology 2000;102:85-8. Ref ID: 25 262 152. Lindes DM. Severe Guillain-Barre syndrome associated with Campylobacter jejuni infection [letter]. Journal of the American Board of Family Practice12:505-Dec. Ref ID: 26 153. Lange D, Aleksic S, Kassubek J, Vrvic MM, Kist M, Steinbruckner B et al. Detection of antibodies against Campylobacter jejuni serogroup PEN O:19 purified flagellar protein in a patient with Guillain-Barre syndrome. Zentralblatt fur Bakteriologie 1999;289:429-44. Ref ID: 30 154 Case records of the Massachusetts General Hospital. Case 39-1999. A 74-year-old woman with acute, progressive paralysis after diarrhea for one week [clinical conference]. New England Journal of Medicine 1999;341:1996-2003. Ref ID: 31 155. Matsuki Y, Hidaka T, Matsumoto M, Fukushima K, Suzuki K. Systemic lupus erythematosus demonstrating serum anti-GM1 antibody, with sudden onset of drop foot as the initial presentation [see comments]. [Review] [25 refs]. Internal Medicine 1999;38:729-32. Ref ID: 37 156. Allen A,.Antony SJ. Severe Guillain-Barre syndrome associated with Campylobacter jejuni infection with failure to respond to plasmapheresis and immunoglobulin. Journal of the American Board of Family Practice 1999;12:249-52. Ref ID: 43 157. Schnorf H, Rathgeb JP, Kohler A. Anti-GQ1b-positive Miller Fisher syndrome in a patient with acute Epstein-Barr virus infection and negative Campylobacter serology. European Neurology 1998;40:177. Ref ID: 59 158. Isaacson M. Guillain-Barre syndrome and Campylobacter infection [letter]. [Review] [3 refs]. Journal of Travel Medicine 1998;5:160. Ref ID: 61 159. Moran AP,.Prendergast MM. Molecular mimicry in Campylobacter jejuni lipopolysaccharides and the development of Guillain-Barre syndrome [letter; comment]. Journal of Infectious Diseases 1998;178:1549-51. Ref ID: 64 160. Hirai K, Kihara M, Nakajima F, Miyanomae Y, Yoshioka H. Immunoadsorption therapy in Guillain-Barre syndrome. Pediatric Neurology 1998;19:55-7. Ref ID: 70 161. Feasby TE,.Hughes RA. Campylobacter jejuni, antiganglioside antibodies, and Guillain-Barre syndrome [editorial]. Neurology 1998;51:340-2. Ref ID: 73 162. Creange A, Lerat H, Meyrignac C, Degos JD, Gherardi RK, Cesaro P. Treatment of Guillain-Barre syndrome with interferon-beta [letter] [see comments]. Lancet 1998; 352: 368-9. Ref ID: 75 163. Shin JE, Ackloo S, Mainkar AS, Monteiro MA, Pang H, Penner JL et al. Lipo oligosaccharides of Campylobacter jejuni serotype O:10. Structures of core oligosaccharide regions from a bacterial isolate from a patient with the Miller-Fisher syndrome and from the serotype reference strain. Carbohydrate Research 1997;305:223-32. 263 164. Berciano J, Figols J, Garcia A, Calle E, Illa I, Lafarga M et al. Fulminant Guillain- Barre syndrome with universal inexcitability of peripheral nerves: a clinicopathological study. Muscle & Nerve 1997;20:846-57. Ref ID: 126 165. Jacobs BC, Schmitz PI, van der Meche FG. Campylobacter jejuni Infection and treatment for Guillain-Barre Syndrome [letter; comment]. New England Journal of Medicine 1996;335:208-9. Ref ID: 155 166. Aguago JM, Ramos JT, Lumbreras C. Campylobacter jejuni infection and Guillain- Barre syndrome [letter; comment]. New England Journal of Medicine 1996;334:802. Ref ID: 156 167. Kimura F, Ito T, Yuki N, Nakajima H, Tanaka T, Shinoda K et al. Longitudinal study of serum and cerebrospinal fluid (CSF) class-specific antibodies against Campylobacter jejuni and GM1 ganglioside in Guillain-Barre syndrome. Internal Medicine 1995;34:1009-14. Ref ID: 165 168. Rees JH, Gregson NA, Hughes RA. Anti-ganglioside antibodies in patients with Guillain-Barre syndrome and Campylobacter jejuni infection [letter; comment]. Journal of Infectious Diseases 1995;172:605-6. Ref ID: 176 169. Yuki N,.Tsujino Y. Familial Guillain-Barre syndrome subsequent to Campylobacter jejuni enteritis [letter]. Journal of Pediatrics 1995;126:162. Ref ID: 186 170. Sugita K, Ishii M, Takanashi J, Niimi H, Yuki N. Guillain-Barre syndrome associated with IgM anti-GM1 antibody following Campylobacter jejuni enteritis. European Journal of Pediatrics 1994;153:181-3. Ref ID: 200 171. Hayashi H, Park-Matsumoto YC, Yuki N, Itoh T, Amakawa T, Muneyuki T. A case of recurrent Guillain-Barre syndrome preceded by different infections [letter]. Journal of Neurology 1993;240:196-7. Ref ID: 213 172. Yuki N, Sato S, Fujimoto S, Yamada S, Tsujino Y, Kinoshita A et al. Serotype of Campylobacter jejuni, HLA, and the Guillain-Barre syndrome [letter]. Muscle & Nerve 1992;15:968-9. Ref ID: 221 173. Yuki N, Yoshino H, Sato S, Shinozawa K, Miyatake T. Severe acute axonal form of Guillain-Barre syndrome associated with IgG anti-GD1a antibodies. Muscle & Nerve 1992;15:899-903. Ref ID: 222 174. Kaldor J, Tong MQ, Dwyer B, Huang ZH, Johnston N, Talman P et al. Guillain- Barre syndrome and Campylobacter jejuni/coli [letter]. Pathology 1992;24:125-6. Ref ID: 223 175. Fujimoto S, Yuki N, Itoh T, Amako K. Specific serotype of Campylobacter jejuni ssociated with Guillain-Barre syndrome [letter]. Journal of Infectious Diseases 1992;165:183. Ref ID: 225 264 176. Callegaro L, Jack DB, SaMSon JC. Campylobacter infections, Guillain-Barre syndrome, and parenteral gangliosides [letter] [see comments]. Lancet 1991;337:789. Ref ID: 232 177. Yuki N, Yoshino H, Sato S, Miyatake T. Acute axonal polyneuropathy associated with anti-GM1 antibodies following Campylobacter enteritis [see comments]. Neurology 1990;40:1900-2. Ref ID: 233 178. Fujimoto S,.Amako K. Guillain-Barre syndrome and Campylobacter jejuni infection [letter]. Lancet 1990;335:1350. Ref ID: 235 179. Goldblatt D. Guillain-Barre syndrome following Campylobacter jejuni enteritis [letter]. Archives of Neurology 1988;45:604. Ref ID: 239 180. Kohler PC,.Goldblatt D. Guillain-Barre syndrome following Campylobacter jejuni enteritis [letter]. Archives of Neurology 1987;44:1219. Ref ID: 242 181. De Bont B, Matthews N, Abbott K, Davidson GP. Guillain-Barre syndrome associated with Campylobacter enteritis in a child. Journal of Pediatrics 1986;109:660-2. Ref ID: 244 182. Speed BR,.Kaldor J. Guillain-Barre syndrome associated with Campylobacter infection [letter]. Australian & New Zealand Journal of Medicine 1985;15:269. Ref ID: 246 183. Pryor WM, Freiman JS, Gillies MA, Tuck RR. Guillain-Barre syndrome associated with Campylobacter infection [letter]. Australian & New Zealand Journal of Medicine 1984;14 :687-8. Ref ID: 247 184. Speed B, Kaldor J, Cavanagh P. Guillain-Barre syndrome associated with Campylobacter jejuni enteritis [letter]. Journal of Infection 1984;8:85-6. Ref ID: 249 185. Constant OC, Bentley CC, Denman AM, Lehane JR, Larson HE. The Guillain-Barre syndrome following Campylobacter enteritis with recovery after plasmapheresis. Journal of Infection 1983;6:89-91. Ref ID: 250 186. Molnar GK, Mertsola J, Erkko M. Guillain-Barre syndrome associated with campylobacter infection [letter]. British Medical Journal Clinical Research Ed 1982;. 285:652. Ref ID: 251 187. Lang DR, Allos BM, Blaser MJ. Workshop summary and recommendations regarding the development of Guillain-Barre syndrome following Campylobacter infection. Journal of Infectious Diseases 1997;176 Suppl 2:S198-S200. Ref ID: 115 265 188. Development of Guillain-Barre Syndrome following Campylobacter Infection. Proceedings of a workshop. Bethesda, Maryland, 26-27 August 1996. Journal of Infectious Diseases 1997;176 Suppl 2:S91-200. Ref ID: 116 Campylobacter and Guillain-Barre Syndrome - science citation index search 1 Altekruse SF, Stern NJ, Fields PI, Swerdlow DL. Campylobacter jejuni - An emerging foodborne pathogen. Emerging Infectious Diseases 1999;5:28-35. 2 Bourke B,.Sherman PM. Gastrointestinal infections in children. Current Opinion In Gastroenterology 1999; 15:79-84. 3 Caccavale A,.Mignemi L. Acute onset of a bilateral areflexical mydriasis in MillerFisher syndrome: A rare neuro-ophthalmologic disease. Journal Of Neuro-Ophthalmology 2000;20:61-2. 4 Corcia P, Beaume A, Guennoc AM, de Toffol B, Preud'homme JL, Autret A. Acute demyelinizing motor neuropathy secondary to gastroenteritis: an atypical form of GuillainBarre syndrome? Revue Neurologique 1999;155:596-7. 5 D'Alessandro R, Casmiro M, Guarino M. Risk factors for Guillain-Barre syndrome: a population-based case-control study. Journal Of Neurology 1999;246:1004-9. 6 Fields PI,.Swerdlow DL. Campylobacter jejuni. Clinics In Laboratory Medicine 1999;19:489-+. 7 Gold R, Reiners K, Toyka KV. Pathogenesis and therapy of Guillain-Barre syndrome. Nervenheilkunde 1999; 18:34-9. 8 Ho T,.Griffin J. Guillain-Barre syndrome. Current Opinion In Neurology 1999;12:389-94. 9 Jiang GX, Cheng Q, Link H, dePedroCuesta J. Epidemiological features of GuillainBarre syndrome in Sweden, 1978-93. Journal Of Neurology Neurosurgery And Psychiatry 1997;62:447-53. 10 Li HF, Yuan JM, Shen BQ, Sun XT, Hao HJ. Relationship between pathogenesis of Guillain-Barre syndrome and Penner's serotypes of Campylobacter jejuni. Chinese Medical Journal 1999;112:794-6. 11 Nachamkin I. Microbiologic approaches for studying Campylobacter species in patients with Guillain-Barre syndrome. Journal Of Infectious Diseases 1997;176:S106-S114. 12 Ravasio A, Pasquinelli M, Dossi BC, Neri W, Guidi C, Gessaroli M et al. Campylobacter jejuni infection and Guillain-Barre syndrome: A case-control study. Neuroepidemiology 1998;17:296-302. 13 Ropper AH, Cros DP, Palmer-Toy DE. A 74-year-old woman with acute, progressive paralysis after diarrhea for one week - Guillain-Barre syndrome. Campylobacter jejuni enteritis. New England Journal Of Medicine 1999;341:1996-2003. 14 Shoenfeld Y, George J, Peter JB. Guillain-Barre as an autoimmune disease. International Archives Of Allergy And Immunology 1996;109:318-26. 266 15 ter Laak MP, Lankhorst A, Schrama LH, Gispen WH. Neuropathies. Neuroscience Research Communications 2000;26:227-39. 16 Van Koningsveld R, van Doorn PA, Schmitz PIM, Ang CW, van der Meche FGA. Mild forms of Guillain-Barre syndrome in an epidemiologic survey in the Netherlands. Neurology 2000;54:620-5. 17 Visser LH, vanderMeche FGA, Meulstee J, Rothbarth PP, Jacobs BC, Schmitz PIM et al. Cytomegalovirus infection and Guillain-Barre syndrome: The clinical, electrophysiologic, and prognostic features. Neurology 1996;47:668-73. 18 Wassenaar TM,.Blaser MJ. Pathophysiology of Campylobacter jejuni infections of humans. Microbes and Infection 1999;1:1023-33. 19 Yuki N,.Miyatake T. Guillain-Barre syndrome and Fisher's syndrome following Campylobacter jejuni infection. Sphingolipids As Signaling Modulators In The Nervous System 1998;845:330-40. 20 Yuki N, Koga M, Hirata K. Is Campylobacter lipopolysaccharide bearing a GD3 epitope essential for the pathogenesis of Guillain-Barre syndrome? Acta Neurologica Scandinavica 2000;102:132-4. 21 Yuki N. Current cases in which epitope mimicry is considered a component cause of autoimmune disease: Guillain-Barre syndrome. Cellular And Molecular Life Sciences 2000;57 :527-33. SHISTOSOMES OCCUPATIONAL RELEVANCE 1. Ayad N. A short review of the epidemiology of schistosomiasis in Africa. [Review] [18 refs]. Egyptian Journal of Bilharziasis 1974;1:9-27. Ref ID: 1788 2. Badawi AF,.Michael MS. Risk factors for hepatocellular carcinoma in Egypt: The role of hepatitis-B viral infection and schistosomiasis. Anticancer Research 1999;19:4565-9. Ref ID: 4374 3. Barbosa FS,.Pereira DCD. Incapacitating effects of schistosomiasis mansoni on the productivity of sugar-cane cutters in northeastern Brazil. American Journal of Epidemiology 1981;114. Ref ID: 3672 4. Bedwani R, Renganathan E, El Kwhsky F, Braga C, Abu SH, Azm TA et al. Schistosomiasis and the risk of bladder cancer in Alexandria, Egypt. British Journal of Cancer 1998;77:1186-9. Ref ID: 2490 5. Blas BL. Agro-engineering and sanitation improvement in the control of schistosomiasis japonica in the Philippines: a review. Southeast Asian Journal of Tropical Medicine & Public Health 1976;7:341-5. Ref ID: 1781 267 6. Bukenya GB, Nsungwa JL, Makanga B, Salvator A. Schistosomiasis mansoni and paddy-rice growing in Uganda: An emerging new problem. Annals of Tropical Medicine & Parasitology 1994;88:379-84. Ref ID: 2831 7. Chandiwana SK, Taylor P, Chimbari M, Ndhlovu P, Makura, O et al. Control of schistosomiasis transmission in newly established smallholder irrigation schemes. Transactions of the Royal Society of Tropical Medicine & Hygiene 1988;82:874-80. Ref ID: 4669 8. Chapman PJ, Wilkinson PR, Davidson RN. Acute schistosomiasis (Katayama fever) among British air crew. BMJ 1988;297:1101. Ref ID: 4671 9. de L, Rocha RS, Almeida Magalhaes MH, Katz N. A clinico-epidemiological survey of schistosomiasis mansoni in a hyperendemic area in Minas Gerais State (Comercinho, Brazil). I. Differences in the manifestations of schistosomiasis in the town centre and in the environs. Transactions of the Royal Society of Tropical Medicine & Hygiene 1985;79:539-45. Ref ID: 1773 10. Hammam HM, Allam FA, Hassanein F. Relationship between pure Schistosoma haematobium infection in Upper Egypt and irrigation systems. Part III: Host characteristics. The prevalence of S. haematobium in relation to religon, occupation, and habits. Gazette of the Egyptian Paediatric Association 1975;23:227-41. Ref ID: 4730 11. Kazura JW, Neill M, Peters PAS, Dennis E. Swamp rice farming: Possible effects on endemicity of Schistosomiasis mansoni and haematobia in a population in Liberia. American Journal of Tropical Medicine & Hygiene 1985;34. Ref ID: 3657 12. Klumpp RK,.Webbe G. Focal, seasonal and behavioural patterns of infection and transmission of Schistosoma haematobium in a farming village at the Volta Lake, Ghana. Journal of Tropical Medicine & Hygiene 1987;90:265-81. Ref ID: 4775 13. Li YS,.Yu DB. Schistosoma japonicum infection among migrant fishermen in the Dongting Lake region of China. Transactions of the Royal Society of Tropical Medicine & Hygiene 1991;85:623-5. Ref ID: 4788 14. Mohamed AM, el Sharkawi FM, el Fiki SA. Prevalence of schistosomiasis among fishermen of Lake Maryut. Egyptian Journal of Bilharziasis 1978;5:85-90. Ref ID: 4816 15. Narain K, Rajguru SK, Mahanta J. Incrimination of Schistosoma spindale as a causative agent of farmer's dermatitis in Assam with a note on liver pathology in mice. Journal of Communicable Diseases 1998;30:1-6. Ref ID: 4824 16. Ndamba J, Makaza N, Kaondera KC, Gomo E. A cross-sectional study on the prevalence and intensity of schistosomiasis among sugar cane cutters in Zimbabwe. Central African Journal of Medicine 1991;37:171-5. Ref ID: 4826 268 17. Ndamba J, Makaza N, Kaondera KC, Munjoma M. Morbidity due to Schistosoma mansoni among sugar-cane cutters in Zimbabwe. International Journal of Epidemiology 1991;20 :787-95. Ref ID: 4825 18. Ross AG, Yuesheng L, Sleigh AS, Yi L, WilliaMS GM, Wu WZ et al. Epidemiologic features of Schistosoma japonicum among fishermen and other occupational groups in the Dongting Lake region (Hunan Province) of China. American Journal of Tropical Medicine & Hygiene 1997;57:302-8. Ref ID: 4864 19. Satti MZ, Sulaiman SM, Homeida MM, Younis SA, Ghalib HW. Clinical, parasitological and immunological features of canal cleaners hyper-exposed to Schistosoma mansoni in the Sudan. Clinical & Experimental Immunology 1996;104:426-31. Ref ID: 4876 20. Satti MZ, Lind P, Vennervald BJ, Sulaiman SM, Daffalla AA, Ghalib HW. Specific immunoglobulin measurements related to exposure and resistance to Schistosoma mansoni infection in Sudanese canal cleaners. Clinical & Experimental Immunology 1996;106:45-54. Ref ID: 3000 21. Tameim O, Abdu KM, El Gaddal AA, Jobin WR. Protection of Sudanese irrigation workers from schistosome infections by a shift to earlier working hours. Journal of Tropical Medicine & Hygiene 1985;88. Ref ID: 3654 22. Van Gompel A, Van den EE, Van den EJ, Geerts S. Laboratory infection with Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine & Hygiene 87:554-Oct. Ref ID: 4913 23. Watts S,.El Katsha S. Irrigation, farming and schistosomiasis: A case study in the Nile delta. International Journal of Environmental Health Research 1997;7:101-13. Ref ID: 2996 269 APPENDIX 1 OCCUPATIONAL TRANSMISION SEARCH STRATEGY 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. exp Occupations exp agriculture/ or exp animal husbandry exp child care/ or exp infant care exp occupational diseases exp health personnel/ or exp military personnel/ or exp occupational groups/ or exp police/ or exp research personnel exp nurseries/ or exp nurseries, hospital/ exp forestry employee.mp. forest.mp. abbatoir.mp. (land adj2 management).mp. (zoo adj2 keeper).mp. “pet adj2 shop”.mp. “workers”.mp. joiner$3.mp. “wood dust”.mp. “occupation”.mp. exp air pollution/ or exp air pollution,indoor/ or/1-18 BACTERIA SEARCH TERMS 20. 21. 22. exp Bacteria bacteri:.mp. 20 or 21 VIRUS SEARCH TERMS 23. 24. 25. exp Viruses/ “virus$2”.mp. 23 or 24 PARASITE SEARCH TERMS 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. exp Parasites exp Helminths exp Trematoda exp Toxoplasma exp Schistosoma parasites.mp. helminths.mp. “flukes”.mp. (toxoplasma or schistosoma).mp. or/26-35 270 FUNGUS SEARCH TERMS 36. 37. 38. 39. 40. 41. exp Allergens exp fungi “fung:”.mp. “yeast”.mp. “toxin”.mp. or/36-41 GENERAL INFECTION TERMS 42. 43. 44. infect:.mp. (“micro-organism” or microb:).mp. 42 or 43 SYSTEMATIC REVIEW FILTER 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. meta-analysis.pt, sh. (meta-anal: or metaanal).tw. (quantiv: review: or quantiv: overview:).tw. (systematic: review: or systematic: overview:).tw. (methodologic: review: or methodologic: overveiw:).tw. (integrative research review: or research integration:).tw. (review.pt,sh. or review:.tw. or overview:.tw. quantitativ: synthes:.tw. 43 or 44 or 45 or 46 or 47 or 48 or 50 (medline or medlars).tw,sh. or embase.tw. (scisearch or psychinfo or psycinfo).tw. (psychlit or psyclit).tw. (hand search: or manual search:).tw. (pooling or pooled analys: or mantel haenszel).tw. (electronic database: or bibliographic database:).tw. (peto or der simonian or dersimonian or fixed effect:).tw. 52 or 53 or 54 or 55 or 56 or 57 or 58 59 and 49 51 or 60 RANDOMISED CONTROLLED TRIAL FILTER 62. random:.tw,sh,pt. or placebo:.tw,sh. 63. (clinical trial or controlled clinical trial).pt. 64. double-blind:.tw,sh. 65. or/62-64 OTHER STUDIES FILTER 66. exp case-control studies/ or exp cohort studies/ or exp cross-sectional studies/ or exp epidemiologic studies/ or exp seroeoidemiologic studies 67. exp epidemiologic study characteristics/ or exp intervention studies/ 68. exp disease outbreaks/ or exp disease reservoirs/ or exp disease transmission/ or exp “environment and public health”/ or exp environmental microbiology/ or exp public health/ 69. Serprevalence.mp. 70. surveillance.mp. 71. survey.mp. 72. or/63-69 271 SEARCH STRATEGIES [numbers is square brackets refer to search terms listed above] (numbers in parenthesis are total papers identified prior to and after applying exclusions) Occupational terms [19] + bacterial terms [22] + systematic review terms [61] (3)(1) Occupational terms [19] + bacterial terms [22] + randomised controlled trials [65] (210)(43) Occupational terms [19] + bacterial terms [22] + other epidemiological studies [72] (3337)(591) Occupational terms [19] + bacterial terms [22] [not the above] (1674)(287) Occupational terms [19] + virus terms [25] + systematic review terms [61] (10)(3) Occupational terms [19] + virus terms [25] + randomised controlled trials [65] (217) (27) Occupational terms[19] + virus terms [25] + other epidemiological studies [72] (2925) (687) Occupational terms [19] + virus terms [25] (3804) not included Occupational terms [19] + parasite terms[35] + systematic review terms[61] (1)(0) Occupational terms[19] + parasite terms [35] + randomised controlled trials [65] (36)(10) Occupational terms [19] + parasite terms [35] + other epidemiological studies [72] (390) (121) Occupational terms [19] + parasite terms [35] [not the above] (159) (36) Occupational terms [19] + fungus terms [41] + systematic review terms [61] (6) (5) Occupational terms [19] + fungus terms [41] + randomised controlled trials [65] (171) (35) Occupational terms [19] + fungus terms [41] (3591) not included Occupational terms [19] + general infection terms [44] + systematic review terms [61] (14) (7) Occupational terms [19] + general infection terms [44] + randomised controlled trials [65] (368) (156) Occupational terms [19] + general infection terms [44] (7943) not inluded 272 CHRONIC HEALTH EFFECTS SEARCHES ADENOVIRUS SEARCH TERMS 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. exp adenoviridae/ adenovirus.mp 1 or 2 exp chronic disease/ chronic infection.mp. persistent infection.mp. latent infection.mp. or/2-5 exp Asthma exp Lung diseases, obstructive/ exp Obesity exp Myocardial disease exp Celiac disease exp NeoplasMS/et [Etiology] Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [3] and [3] and [3] and [3] and [3] and [3] and [3] and [8] [9] [ 10] [ 11] [ 12] [ 13] [14] (81) (26) (84) (3) (36) (22) (198) (5) (3) (2) (4) (2) Cytomegalovirus search terms 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. exp cytomegalovirus/ or exp cytomegalovirus infections/ cytomegalovirus.mp exp chronic disease p ersistent infection.mp. persistent disease.mp. latent infection.mp. chronic disease.mp. exp aids-related opportunistic infections/ or exp immunocompromised host/or exp immunologic deficiency syndromes/ exp postoperative complications/ or exp transplants exp bone marrow transplantation/ or exp graft rejection/ or exp heart transplantation/ or exp kidney transplantation/ or exp transplantation immunology/ or exp transplantation, homologous/ exp angioplasty/ or angioplasty, balloon/ or exp angioplasty , balloon, laser-assisted/ or exp angioplasty, laser/ or exp angioplasty, transluminal, percutaneous coronary/ exp Coronary disease exp Artherosclerosis 273 14. 15. 16 17. 18. 19. exp arterial occlusive diseases/ or exp carotid artery diseases/ or exp coronary arteriosclerosis/ or mitral valve stenosis 1 or 2 or/3-7 or/ 8-10 or/12-14 exp Guillain-barre syndrome/ Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [15] and [16] not [17] (199) [15] and [18] not [11] (225) (30) [15] and [19] (94) (6) Herpes viruses search terms 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. exp simplexvirus/ exp herpesviridae/ or exp herpesviridae infections/ or exp herpesvirus 6, human exp chickenpox/ or exp herpes zoster/ or exp herpesvirus 3, human/ (Herpes adj3 virus).mp. exp Multiple sclerosis/ multiple sclerosis.mp. exp Alzheimer disease/ alzheimer.mp. exp Fatigue syndrome, chronic/ exp Coronary disease exp Artherosclerosis exp arterial occlusive diseases/ or exp carotid artery diseases/ or exp coronary arteriosclerosis/ or mitral valve stenosis or/1-4 5 or 6 7 or 8 or/10-12 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [13] [13] [13] and and and [14] [15] [9] (389) (67) (140) (27) (5) (13) [13] and [16] (164) 274 Measles search terms 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. exp measles virus/ measles.mp. exp Crohn disease/ Crohn's disease.mp crohn.mp. exp multiple sclerosis multiple sclerosis.mp 1 or 2 or/3-5 6 or 7 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [8] [8] and and [9] [10] (74) (14) (643) – [8] and [10] Reviews (medline filter) (39) too numerous to review all abstracts therefore applied epidemiological study filters which proved unsuccessful. Parvovirus search terms 1. 2. 3. 4. 5. 6. exp parvovirus/ or exp parvovirus b19, human/ parvovirus.mp exp anaemia/ or exp chronic disease/ chronic anaemia.mp. 1 or 2 3 or 4 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [5] and [6] (547) (11) Chlamydia search terms 1. 2. 3. 4. 5. 6. exp chlamydia/ or exp chlamydia infections/ chlamydia.mp. exp coronary disease/ coronary.mp. exp Artherosclerosis artherosclerosis.mp. 275 7. 8 9. 10. 11. 12. 13. 14. 15. 16. 17. exp asthma/ exp chronic disease asthma.mp. chronic.mp. exp Guillain-barre syndrome/ Guillain-Barre.mp. exp Cerebellar ataxia 1 or 2 or/3-6 or/7-10 or/11-13 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [14] and [15] (408) - too numerous to review all abstracts therefore applied epidemiological study filters – see table in main text for results (48) [14] and [16] (617) - too numerous to review all abstracts therefore applied epidemiological study filters – see table in main text for results [14] and [17] (4) Coxiella search terms 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. exp coxiella/ or exp Coxiella burnetii coxiella.mp. exp heart valves/ heart valves.mp. exp endocarditis/ or exp endocarditis, bacterial/ or exp endocarditis, subacute bacterial/ endocarditis.mp. exp brain diseases/ or exp mental disorders/ or exp nervous system diseases/ or exp psychotic disorders/ neuropsychiatric.mp. 1 or 2 or/3-8 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [9] and [10] (154) (7) 276 Bartonella search terms 1. 2. 3. 4. 5. 6. 7. 8. exp Bartonella bartonella.mp. exp endocarditis/ or exp endocarditis, bacterial/ or exp endocarditis, subacute bacterial/ endocarditis.mp. exp diabetic retinopathy/ or exp endothelium/ or exp fundus oculi/ or exp hemangioma/ or exp hemangioma, capillary/ or exp neovascularization, pathologic/ or exp retina/ or exp retinal diseases/ or exp retinal neoplasMS/ or exp retinal neovascularization vasoproliferative.mp. 1 or 2 or/ 3-6 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [7] and [8] (100) (19) Borrelia search terms 1. 2. 3. 4. 5. 6. exp borrelia/ or exp borrelia infections Borrelia.mp. exp chronic disease chronic.mp. 1 or 2 3 or 4 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [5] and [6] (511) - too numerous to review all abstracts therefore applied epidemiological study filters which proved unsuccessful. [5] and [6] Reviews (medline filter) (122) (69) Campylobacter search terms 1. 2. 3. 4. 5. 6. 7. 8. exp Campylobacter/ campylobacter.mp. exp Guillain-barre syndrome/ Guillain-Barre .mp exp arthritis, reactive/ or exp reiter’s disease/ Reiter's.mp. 1 or 2 or/3-6 277 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [7] and [8] (211) - not specific enough and to numerous to review all abstracts therefore applied epidemiological study filters which proved unsuccessful. [5] and [6] Reviews (medline filter) (77) (48) Helicobacter pylori search terms 1. 2. 3. 4. 5. 6. 7. 8. exp Helicobacter pylori/ Helicobacter pylori.mp. exp coronary disease coronary.mp. exp Crohn disease crohn.mp. 1 or 2 or/3-6 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) (numbers in bold are papers identified by ISI search prior to duplicates being removed) [7] and [8] (137) (17) Salmonella typhi search terms 1. 2. 3. 4. exp Salmonella typhi Salmonella typhi.mp exp biliary tract/ or exp biliary tract diseases/ or exp biliary tract neoplasMS/ 1 or 2 Search strategies [numbers is square brackets refer to search terMS listed above] (numbers in parenthesis are total papers identified prior to reading abstracts and excluding papers) [3] and [4] (44) (6) 278 APPENDIX 2 CHRONIC HEALTH EFFECTS OF EXPOSURE TO BIOLOGICAL AGENTS DATA EXTRACTION SHEET REFERENCE MANAGER ID ……………. TITLE ………………………………………………………………………………… AUTHOR(S) …………………………………………………………………………. JOURNAL, DATE ETC ……………………………………………………………… Paper identified by 1. Medline search; 2. Embase serach; 3. Cochrane search; 4. ISI search; 5. Hand search; 6. Other Country where the study was conducted ……………………………………………. Description of the evidence Exposure or intervention ……………………………………………………………. Outcome ……………………………………………………………………………. Study design ………………………………………………………………………… Study population ……………………………………………………………………. Main result …………………………………………………………………………. Potential sources of bias (see check list) Potential confounding (see check list) Potential chance variation (see check list) Conclusions of authors: accepted not accepted as appropriate) Comments: Hierarchy of evidence level ………………………………………………………. 279 (circle To asses the extent to which bias, confounding and chance could have led to the conclusions of the papers reviewed the following checklists were used: Check-list for meta-analysis/systematic literature reviews 1. 2. Is the research question/hypothesis clearly stated? Are the methods clearly stated including data sources and inclusion/exclusion criteria and are there any obvious omissions? Was publication bias considered? Are excluded studies described? Did the authors assess the quality of the studies, are their assessments free from bias (blind) and reproducible? Was variation in the findings of studies analysed in terMS of different study designs, populations, exposures or outcomes? Did the meta-analysis (if any) include only papers with uniform exposures (clinical severity) and outcomes? Does the interpretation include reference to sample size, statistical difference vs clinical importance, outliers, subgroup analysis and fail safe n. 3. 4. 5. 6. Check-list for randomised control trials 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Is the research question/hypothesis clearly stated? Is the sample representative of the study population (case definition practical and reproducible/exclusion criteria, disease spectrum)? Was an a priori estimate made of sample size and what was the power of the study? What was the method of allocation to intervention/control group and were the groups comparable and treated equally? Was a placebo/double-blinding/cross-over used? Is the intervention clearly stated and reproducible (co-interventions)? Are the base-line and follow-up measurements reproducible and were methods validated? Is the duration of follow-up stated and appropriate? What proportion of subjects dropped out and was the analysis based on intention to treat? Are the statistical tests appropriate and used to control for potential confounding factors? Check-list for case control studies 1. 2. 3. 4. 5. 6. 7. Is the research question/hypothesis clearly stated? Was an a priori estimate made of sample size and what was the power of the study? Is the case definition clearly stated and do the cases represent the whole case population (diagnosis, severity)? Are the controls from a similar population, are multiple control groups/ matching used? Are response rates for cases and controls given and are low rates likely to have affected the findings of the study? Were the same techniques/researchers/tools/observation techniques used for cases and controls? Was data validated by multiple sources (written records etc.)? 280 Check-list for cohort and cross-sectional studies (including seroprevalence studies) 1. Is the research question/hypothesis clearly stated? 2. Was an a priori estimate made of sample size and what was the power of the study? 3. Is the case definition clearly stated and do the cases represent the whole case population (diagnosis, severity)? 4. Are exposures clearly defined and measured? 5. A re measurements reliable and validated (standardised, calibrated devices, independent trained personnel, multiple observers/data sources)? 6. Were other differences between the exposed and unexposed groups measured and considered in the analysis? 7. What were the response rates, are non-participants characterised and are low rates likely to have affected the findings of the study? 8. Was the length of follow-up appropriate? 9. Are the cohorts periodically re-examined to determine exposure status? 10. Are time-order relationships clear? 11. What were the drop out rates and are they likely to have affected the findings of the study? 12. Are both groups observed equally using identical methods and tools? 13. Are the statistical techniques appropriate? 281 GLOSSARY OF ABBREVIATIONS USED AD CFS CHD CMV CNS CRD DNA EBV EID HHV6 HSV HTLV (I,II,III) IARC IBD MRSA MS PBMC PCF PCR PHLS RNA TAQ UGI UWCM VTEC O157 VZV WHO Alzheimer’s Disease Chronic Fatigue Syndrome Coronary Heart Disease Cytomegalovirus Central Nervous System Centre for Reviews and Dissemination Deoxyribonucleic acid Epstein-Barr Virus Emerging Infectious Diseases Human Herpesvirus 6 Herpes simplex virus Human T cell lymphotropic virus (types I, II or III) International Agency for Research on Cancer Inflammatory Bowel Disease Methicillin resistant Staphylococcus aureus Multiple Sclerosis Peripheral blood mononuclear cells Pharyngoconjuctival fever Polymerase chain reaction Public Health Laboratory Service Ribonucleic acid Thermos aquaticus Upper gastrointestinal University of Wales College of Medicine Verotoxin producing Escherichia coli serotype O157 Varicella zoster virus World Health Organisation Printed and published by the Health and Safety Executive C1.25 8/02 ISBN 0-7176-2542-7 RR 006 £25.00 9 780717 625420