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Margaret Ann Pisani, M.D., M.P.H. CURRICULUM VITAE Date of Revision: 07/10/2015 Name: Margaret Pisani, M.D., M.P.H. School: Yale University School of Medicine Education: B.S. Iona College (Physics) 1985 M.S. New Jersey Institute of Technology (Biomedical Engineering) 1987 M.D. Temple University School of Medicine 1994 M.P.H. Yale University School of Public Health (Chronic Disease Epidemiology) 2001 Career/Academic Appointments: 1987-1990 Instructor/Research Engineer, Anesthesiology, University of Connecticut Health Center, Farmington, CT 1994-1995 Intern, Internal Medicine, Yale-New Haven Hospital, New Haven, CT 1995-1997 Resident, Internal Medicine, Yale-New Haven Hospital, New Haven, CT 1997-1998 Chief Resident, Internal Medicine, Yale-New Haven Hospital, New Haven, CT 1998 -2001 Postdoctoral Fellow, Pulmonary & Critical Care Medicine, Yale University School of Medicine, New Haven, CT 2001- 2002 Instructor of Medicine, Pulmonary & Critical Care Medicine Yale University School of Medicine, New Haven, CT 2002-2011 Assistant Professor of Medicine, Pulmonary & Critical Care Yale University School of Medicine, New Haven, CT 2011-Present Associate Professor of Medicine, Pulmonary & Critical Care Yale University School of Medicine, New Haven, CT Administrative Positions: 2003-2005 Associate Medical Director, Respiratory Care, Yale-New Haven Hospital, New Haven, CT 2008-Present Director, Pulmonary & Critical Care Fellowship Program, Yale Univ. School of Medicine, New Haven, CT 2011-2013 Associate Director, Winchester Chest Clinic, Yale-New Haven Hospital, New Haven, CT Board Certification: American Board of Internal Medicine 1998; Recertified 2009 American Board of Internal Medicine, Pulmonary Medicine 2000, Recertified 2010 American Board of Internal Medicine, Critical Care Medicine 2001, Recertified 2011 Professional Honors & Recognition: International/National/Regional 2003-2009: NIH Loan Repayment Program 2006: William B. Abrams Award in Geriatric Clinical Pharmacology 1 Margaret Ann Pisani, M.D., M.P.H. 2001: 1994: 1993: CHEST Foundation Young Investigator Award The Emanuel M. Weinberger Award for Achievement in Rheumatology John Creswell Memorial Award for Outstanding Performance in Medicine University 1997-1998: Chief Medical Resident, Yale-New Haven Hospital, New Haven CT Grants/Clinical Trials History: Current Grants Agency: CTSA/YCCI Yale Center for Clinical Investigation ID# UL1 TR000142 KL2 TR000140 NIH (Sherwin) Title: Using noninvasive electroencephalography and cerebral oximetry monitoring to understand brain physiology in critically ill patients with sepsis PI: Emily Gilmore, MD Role: Mentor for YCCI Career Development Award Project Period: 10/1/14-9/30/16 Agency: ID# Title: Yale Claude D. Pepper Older Americans Independence Center P30AG021342 NIH/NIA Characterization of sleep and brain dysfunction markers on EEG in older adults admitted to the MICU PI: Melissa Knauert, MD, PhD Role: Mentor for Research Career Development Award Project Period: July 1, 2014-June 30, 2016 Agency: ID# Title: NIH/NIA R01 AG035117-01A1 The MIND USA Project. RCT comparing haloperidol, ziprasadone and placebo for ICU delirium. PI: E. Wesley Ely, MD Role: Site PI Percent Effort: 5% Project Period: 7/1/11-11/30/15 Agency: NINR ID# 120NR014126-0 Title: Yale Center for Sleep Disturbance in Acute and Chronic Conditions PI: Nancy Redeker PhD, Klar Yaggi MD, MPH Role: Mentor for Pilot Project Project Period: 9/27/2012 – 6/30/2017 Past Grants Agency: NIH / NHLBI / ARRA Stimulus Funds I.D.# 5RC1HL100347-02 (Crothers) Title: “Risk, Severity, and Outcome of Bacterial Pneumonia in an HIV +/- Veteran Cohort” PI: Kristina Crothers, MD Role: Co-PI Percent Effort: 1.2 calendar months 2 Margaret Ann Pisani, M.D., M.P.H. Project period: 9/30/09-7/31/12 Agency: NIH/NINR I.D.# R21 NR011066-01A1 (Pisani) Title: Feasibility of measuring sleep in an ICU setting using portable polysomnography Role: PI Project Period: 9/1/09-8/31/11 Agency: The Chest Foundation I.D.# BI Clinical Research Award in Women’s Pulmonary Health Title: Gender differences as they relate to outcome in an older ICU cohort PI: Margaret Pisani, M.D., M.P.H. Percent effort: 5% Direct costs per year: $10,000 Total costs for project period: $10,000 Project period: 10/1/08-9/30/09 Agency: NIH/NIA I.D.# K23 AG 23023-01A1 Title: Impact of psychoactive medications on outcomes in older ICU patients PI: Margaret Pisani, M.D., M.P.H. Percent effort: 75% Direct costs per year: $146,750 Total costs for project period: $763,830 Project period: 9/30/2004-6/30/2009 Agency: Yale Mentored Clinical Scholar Program (K12 Award) Title: Impact of psychoactive medications on outcomes in older ICU patients PI: Margaret Pisani, M.D., M.P.H. Percent Effort: 90% Total amount of grant ($120,000/year) Project Period: 7/1/2004-9/30/2004 * (*This grant was terminated due to concurrent receipt of the K23) Agency: NIH/NIA I.D.# Yale Pepper Center Early Research Career Development Award Title: Contribution of multiple risk factors to ICU outcomes in older patients PI: Mary Tinetti Role: Investigator Percent Effort: 25% Total cost for project period: $150,000 Project Period: 9/1/2002-8/31/2005 Agency: Merck/American Federation Aging Research I.D.# Junior Investigator Award in Geriatric Clinical Pharmacology Title: Impact of sedative use on outcomes in older intensive care unit patients PI: Margaret Pisani Percent Effort: 20% Total cost for project period: $120,000 Project Period: 7/1/2002- 6/30/2004 3 Margaret Ann Pisani, M.D., M.P.H. Agency: I.D.# Title: American Lung Association Clinical Research Grant Prevalence of preexisting cognitive impairment and its impact on use of interventions and outcomes in older ICU patients PI: Margaret Pisani Percent Effort: 20% Total cost for project period: $70,000 Project Period: 7/1/2002-6/30/2004 Agency: The Chest Foundation I.D.# T. Franklin Williams Scholar Award Title: The contribution to psychoactive drug use to poor outcomes in older ICU patients PI: Margaret Pisani Percent Effort: 25% Total cost for project period: $150,000 Project Period:7/1/2002-6/30/2004 Agency: The Hartford Foundation/NIA I.D.# Internal Medicine Subspecialty Fellowship in Aging Title: Cognitive Impairment in Elderly Medical Intensive Care Unit Patients PI: Mary Tinetti Role: Investigator Percent effort: 50% Total cost for project period: $70,000 Project Period: 7/1/2000-6/30/2002 Invited Speaking Engagements, Presentations, Symposia & Workshops Not Affiliated with Yale: International/National 2014: American College of Chest Physicians, Austin, TX, Invited Speaker: Women’s Health Network Featured Lecture, “Women, lung disease and personalized medicine: Ready for prime time?” 2013: American Thoracic Society, Philadelphia, PA, Session Moderator: Thematic Poster Session, “Taking it to the house: great cases in critical care” 2012: American College of Chest Physicians, Atlanta, GA, Session Moderator: Poster Discussion Session “Non-pulmonary critical care” American Thoracic Society, San Francisco, CA. Session Moderator: Poster Discussion Session, “Pulmonary Infections and Tuberculosis: Case Reports of Note” Society for Critical Care Medicine; Current Concepts in Critical Care, Houston, TX, Invited Speaker, “Delirium Assessment Tools” 2011: French Intensive Care Society Annual Meeting, Versailles, France, Invited Speaker, “Environmental treatments for delirium” 4 Margaret Ann Pisani, M.D., M.P.H. American Thoracic Society, Denver, CO, Session Moderator: Poster Discussion Session, “Non-pulmonary critical care” 2010: Advancing Delirium Science Department of Veterans Affairs, Baltimore, MD Invited Speaker: “Delirium in the ICU” American Thoracic Society, New Orleans, LA, Session Moderator: Poster Discussion Session, “Non-pulmonary critical care” 2008: German Society of Anesthesiology and Intensive Care Medicine, Berlin, Germany, Invited Speaker: “Delirium and the role of sedative medications” German Society of Anesthesiology and Intensive Care Medicine, Berlin, Germany, Invited Speaker, “Implementation of delirium screening in the ICU” American Thoracic Society, Toronto, CN, Session Chair, Poster Discussion: “Non-pulmonary Critical Care” 2007: NIA Seminar on Critical Illness in Older Patients, Washington, DC, Invited Speaker, “Delirium in the ICU” 2006: American College of Chest Physicians, Salt Lake City, UT, Invited Speaker, “Does age impact on outcomes from critical care” American College of Chest Physicians, Salt Lake City, UT, Session Chair, “Caring for the critically ill geriatric patient” American Thoracic Society National Meeting, San Diego, CA, Session Chair, “Critical care of the geriatric patient” American Thoracic Society National Meeting, San Diego, CA, Invited Speaker, “Monitoring sedation and delirium in the ICU” Gerontological Society of America, Chicago, IL, Invited Speaker, “How I started a clinical research career” 2005: American College of Chest Physicians Academic Leadership Conference, Montreal CN, Invited Speaker, “Tips for Succeeding in Academic Medicine” 2004: Pennsylvania Thoracic Society Annual Meeting, Pittsburgh, PA, Invited Speaker, “Delirium in Older ICU Patients” 2003: American College of Chest Physicians, Orlando, FL, Invited Speaker, Panel on Sedation in the ICU, “Cognitive Impairment in the ICU, how do I recognize It?” American Thoracic Society, Seattle WA, Session Chair: “Sedation in the ICU” 2003-2007: American College of Chest Physicians Academic Leadership Conference, Invited Speaker, “Keys to Starting a Clinical Research Career” 5 Margaret Ann Pisani, M.D., M.P.H. Regional 2015 Invited Speaker: “Sleep and circadian rhythm alterations in aging and illness” Hebrew Senior Life, Harvard University. Cedartree Visiting Professor. Invited Speaker: “Addressing challenging clinical research questions in critically ill patients with novel analytical techniques.” Beth Israel-Deaconness Hospital, Department of Medicine Visiting Professor, Harvard University. Invited Speaker: Clinical research questions in older, critically ill patients.” Brigham & Women’s Hospital, Department of Pulmonary & Critical Care, Harvard University. Invited Speaker: “Delirium and sleep in the ICU” Tufts University, Division of Pulmonary & Critical Care Medicine 2014 Invited Speaker: “Sleep in the ICU: Absent, Impact, Improvement” Connecticut Pulmonary Society Annual Meeting 2012 Invited Speaker: “Confusion, drugs and decline: Challenges for caring for the older patient in the ICU”. Rhode ICU Collaborative Outcomes Congress, Warwick RI 2010 Iona College, New Rochelle, NY, Invited Speaker, “Career Development” Tufts University, Boston, MA, Invited Speaker: “Delirium and a Research Career” St. Mary’s Hospital Grand Rounds, Waterbury, CT, Invited Speaker, “Delirium in the ICU” 2009 T. Franklin Williams Scholars Program Annual Alumni Meeting, Austin, TX, Session Moderator, “Foundation Funding” T. Franklin Williams Scholars Program Annual Alumni Meeting, Austin, TX, Session Moderator, “Top secrets of writing a successful aging related research grant” T. Franklin Williams Scholars Program Annual Alumni Meeting, Austin, TX, Invited Speaker, “Research Update” Norwalk Hospital, Norwalk, CT, Invited Speaker, “Clinical Research” 2008 Norwalk Hospital, Norwalk, CT, Invited Speaker, “Delirium in the ICU” 2007 Brown University School of Medicine, Providence, RI, Invited Speaker, “Delirium in the ICU: A long way to go” Peer-Reviewed Presentations & Symposia Given at Meetings Not Affiliated With Yale: International/National 6 Margaret Ann Pisani, M.D., M.P.H. 2015: American College of Chest Physicians, Montreal, BC, Session Moderator, American College of Chest Physicians, Montreal, BC, Invited Speaker, 2014: American College of Chest Physicians, Austin, TX, Session Moderator, “ICU Infections” American College of Chest Physicians, Austin, TX, Session Moderator, “Advances in COPD Treatments” 2013: American College of Chest Physicians, Chicago, IL, Invited Speaker, “Delirium: Best practices to identify and prevent” American College of Chest Physicians, Chicago, IL, Invited Speaker, “Sleep in critically ill patients: Where are we now?” American College of Chest Physicians, Chicago, IL, Session Chair, “A new frontier: Sleep in the ICU exploration beyond the sleep laboratory” American College of Chest Physicians, Chicago, IL, Session Moderator, “Nonpulmonary critical care” American College of Chest Physicians, Chicago, IL. Session Moderator, “Quality improvement in the ICU” American College of Chest Physicians, Chicago, IL, Session Moderator, “End of Life” American Thoracic Society, Philadelphia PA, Invited Speaker, “Delirium and the hazards of medication use in older ICU patients” 2009 American College of Chest Physicians, San Diego, CA, Invited Speaker, “Gender differences as they relate to outcome in an older ICU cohort” 2007 American Thoracic Society, San Francisco, CA, Invited Speaker, “Psychoactive medications and the duration of delirium in an ICU population” 2006 American Thoracic Society, San Diego, CA, Invited Speaker, “Under recognition of preexisting cognitive impairment by physicians in older patients and its effect on ICU outcomes” 2004 American Geriatric Society, Las Vegas, NV, New Frontiers in Geriatrics: The Jahnigen and Williams Awardees Report on Research Leading to Improved Care by Surgical and Medical Sub-specialists, Invited Speaker, “Risk factors for poor outcomes in older ICU patients” 2003 American College of Chest Physicians, Women’s Health Network, Annual Meeting, San Diego, CA, Invited Speaker, “Risk factors for poor outcomes in older ICU patients: the contribution of psychoactive drug Use” 7 Margaret Ann Pisani, M.D., M.P.H. American College of Chest Physicians, San Diego, CA, Invited Speaker, “Cognitive impairment in the ICU, why is it important and how do I recognize it?” 2001 American College of Chest Physicians, Philadelphia, PA, Invited Speaker, “Cognitive impairment in older medical intensive care unit patients: Physician recognition, intensity of care and outcomes” Gerontological Society of America, Chicago, IL, Invited Speaker, “Preexisting cognitive impairment in older patients admitted to the intensive care unit” Regional 2004 Connecticut Thoracic Society Research Meeting, New Britain, CT, Invited Speaker, “Risk Factors for Poor Outcomes in Older ICU Patients” Yale Affiliated Talks: 2015 PCCSM Fellows Research Retreat, “What to expect, what to request: The mentor-mentee relationship” Waterbury Hospital Medical Grand Rounds, 2014 PCCSM Summer Lecture Series, “Altered mental status in the intensive care unit” Resident Reflection Rounds, Faculty Moderator Danbury Hospital, Resident Lecture, “Mechanical Ventilation” Greenwich Hospital, Resident Lecture, “Sleep and altered mental status in critically ill patients” PCCSM Fellows Research Retreat, “What to expect, what to request: The mentor-mentee relationship” Program on Aging Research Seminar, “Dementia, delirium and sleep: critically important to older ICU patients” 2013 Winchester Chest Clinic Fellows State of the Art Conference, Steroids in COPD Exacerbations, what does the evidence show?” Aging Brown Bag Lunch, “Career Paths-Struggles and Accomplishments” Greenwich Hospital, Resident Lecture, “Sleep and delirium in the ICU” Intern Reflection Rounds, Faculty Moderator Yale Physician’s Assistant Program Lecture, “Delirium, sedation and pain in the ICU” 8 Margaret Ann Pisani, M.D., M.P.H. 2012 Winchester Chest Clinic Fellows State of the Art Conference, “Tiotropium in Asthma” Griffen Hospital ICU Teaching Rounds, “Management of Acute Liver Failure”, “Acid-Base Disorders”, Assessment and Treatment of Delirium”, “Mechanical Ventilation” PCCM Fellowship Summer Lecture Series, “Delirium in the ICU” Student-Faculty Rounds Ambulatory Component of the Internal Medicine Clerkship, Pulmonary Moderator PCCM Fellows Clinic Conference, “Vitamin D and COPD” Geriatrics Brown-Bag Lunch Series, Invited Speaker, “Research Career Development” Surgical ICU Nursing Inservice, “Delirium assessment in the ICU” Intern Reflection Rounds, Faculty Moderator 2011: PCCM Fellows Clinic Conference, “Evaluation of ILD-Case Based Conference”, PCCM Fellows Clinic Conference, “Bariatric Surgery-Pre-operative Evaluation”, October 2011 PCCM Fellowship Summer Lecture Series, “Introduction to Clinical Research” PCCM Fellows Clinic Conference, “Lung volume reduction surgery” PCCM Fellows Clinic Conference, “How to make sense of the patient with isolated restriction” 2010: PCCM Fellows Clinic Conference, “Inhaled Anti-cholinergic Risk” PCCM Fellowship Summer Lecture Series, “Delirium and Sedation in the ICU” Greenwich Hospital, Greenwich CT, “Sarcoidosis” 2009 PCCM Research Conference, “Clinical Research in the ICU” PCCM Fellowship Summer Lecture Series, “Delirium and Sedation in the Elderly ICU Patient” Pulmonary Research in Progress, “Clinical research in the ICU” 2008 Yale Internal Medicine Resident Noon Conference, “Monitoring delirium and sedation in the ICU” 9 Margaret Ann Pisani, M.D., M.P.H. 2007 PCCM Fellowship Summer Lecture Series, “Study Design, Meta-analysis, RCT's & Medical Decision Making” PCCM Fellowship Summer Lecture Series, “Monitoring Pain, Agitation and Delirium in the ICU” PCCM Fellowship Summer Lecture Series, “How to Present in State Chest & Journal Club” Biomedical Research Seminar, “Delirium and the challenges of clinical research in the ICU” Pulmonary Research in Progress, “Delirium in the ICU: A long way to go” Aging Research Seminar, “Delirium and the challenges of clinical research in the ICU” Nursing Education Conference, “Delirium in the ICU: What is all the confusion about?” 2005 Yale Medical Grand Rounds, “Delirium in the ICU” 2006 Pulmonary State Chest Conference, “Challenges for caring for the geriatric patient in the ICU” Pulmonary Research in Progress, “Delirium in the ICU” Yale Claude D. Pepper Center Retreat, “T. Franklin Williams Scholar Program” Medical ICU Nursing Inservice, “Delirium in the ICU” 2004 Pulmonary State Chest Conference, “Cognitive impairment in the ICU” Pulmonary Research in Progress, “Dementia, delirium and psychoactive drugs: challenges of clinical research in the ICU” Aging Biomedical Research Conference, “Risk factors for poor outcomes in older ICU patients” 2003 Medical ICU Nursing Inservice, “Cognitive impairment in the ICU, Why is it important and how do I recognize it?” Griffen Hospital Geriatric Grand Rounds, “Cognitive impairment in the ICU” PCCM Fellowship Summer Lecture Series, “Endocrine disorders in the ICU” PROFESSIONAL SERVICE Peer Review Groups/Grant Study Sections/Advisory Boards 2006-2007 UpToDate-Integrating Geriatrics into Subspecialties 10 Margaret Ann Pisani, M.D., M.P.H. 2003-2004 2006-2010 2006-present 2011-present 2011-present 2011-present 2012 2012-present 2013-present 2013-present 2014-present 2015-present American Board of Internal Medicine Subspecialty Recertification Project. Infusing Geriatrics into the Subspecialties of Medicine Grant Reviewer, CHEST Foundation Geriatric Development Research Awards Abstract Reviewer, American College of Chest Physicians Annual Meeting Advisory Board, Center of Excellence for Delirium in Aging: Research, Training, and Educational Enhancement. (CEDARTREE) American College of Chest Physicians Scientific Presentations and Awards Committee Member, Safety Advisory Board, SAGES Delirium Program Project Grant Grant Reviewer, NIH Clinical and Translational Science Award, (CTSA), Albert Einstein College of Medicine Sleep in the ICU Task Force. Co-Chair Member, Scientific Programming Committee, Connecticut Thoracic Society Member Executive Committee, Center of Excellence for Delirium in Aging: Research, Training and Educational Enhancement (CEDARTREE) Member, Pain, Agitation, Delirium (PAD) Guidelines committee member Member, American Board of Internal Medicine, Critical Care Medicine board review committee Journal Service 2007 Guest Editor, Respiratory Disease in Older Patients, Clinics in Chest Medicine 2007-2012 Editor, Pulmonary & Critical Care & Sleep Updates (PCCSU), American College of Chest Physicians 2001-present Reviewer for JAMA, Archives of Internal Medicine, BMJ, Critical Care Medicine, Intensive Care Medicine, Critical Care, Journal of the American Geriatrics Society 2013-present Editorial Board, Heart & Lung: The Journal of Acute and Critical Care Professional Service for Professional Organizations: Association of Subspecialty Professors 2008-present Member American College of Chest Physicians 2003-present Member, Women’s Health Network 2003-present Fellow 2005-present Member, Chest Foundation Community Service 2007-2012 Editor, PCCSU Online 2011-present Member, Scientific Programming Advisory Committee ACCP 2013-present Vice-Chair, Scientific Programming Advisory Committee ACCP 2013-present Steering Committee, Women’s Health Network ACCP 2014-present Member, Critical Care Network American Thoracic Society 2001-present Member, Clinical Problems Assembly 2001-present Member, Critical Care Assembly 2014-present Member, Sleep and Neurobiology Assembly 2015-present Member, Education Assembly Society for Critical Care Medicine 11 Margaret Ann Pisani, M.D., M.P.H. 2001-present Member, Internal Medicine 2014-present Member, Pain, agitation, delirium (PAD) Guidelines Revision Committee Yale University Service: Medical School Committees 2014 Medical Student Thesis Reader 2008-2011 Graduate Medical Education Committee Departmental Committees 2009 Geriatric Section Chief Search Committee 2001-2004 Internship Selection Committee 2007-2012 Internal Medicine Research Advisory Panel 2012-present Physician Scientist Recruitment Committee Section Committees 2003 Program on Aging Research Career Development Core Planning Committee 2006-2009 Pulmonary Faculty Recruitment Selection Committee 2006-present PCCSM Faculty Schedule 2009-2012 Fellowship Curriculum Committee, Chair 2009-present Fellowship Curriculum Committee, Member 2009-present 4th Year of Fellowship Committee, Chair 2009-present Fellowship Research Advisory Committee 2012-present Fellowship Milestone Committee, Chair 2012-present MICU Committee Hospital Boards & Committees 2007 Alcohol Withdrawal Treatment Protocol Committee, YNHH 2006, 2012 Delirium Treatment Protocol Committee, YNHH 2011-present Sedation Protocol Committee, YNHH 2014-present MICU Alarm Committee, YNHH Public Service 2007-2009 LHUMC Children’s Center Board Member 2006-2013 The Chest Foundation Community Outreach Program 2006-2011 Angel Tree Coordinator, LHUMC 2005-2006 Tashua School, Junior Achievement Course Leader 2004-2005 Cub Scout Leader, Tashua Elementary School 2011-present Tashua School, Junior Achievement Course Leader 2013 Tashua School Brownie Troop No Smoking Education Bibliography: Peer Reviewed Original Research 1. Moslehi F, Ligas JR, Pisani M, Epstein MAF. The Unsteady Form of the Bernoulli Equation for Estimating Pressure Drop in the Airways. Respiration Physiology. 1989; 76: 319-326. PMID:2749031 12 Margaret Ann Pisani, M.D., M.P.H. 2. Pisani MA, Redlich CA, McNicoll L, Ely W, Inouye SK. Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients. Chest 2003;124:2267-74. PMID:14665510 3. McNicoll L, Pisani MA, Zhang Y, Ely EW, Siegel M, Inouye SK. Delirium in the intensive care unit: Occurrence and clinical course in older patients. J Amer Geriatr Soc. 2003;51:591-8. PMID:12752832 4. Pisani MA, Inouye SK, McNicoll L, Redlich CA. Screening for preexisting cognitive impairment in older intensive care unit patients: Use of proxy assessment. J Amer Geriatr Soc. 2003;51:689-93. PMID:12752846 5. McNicoll L, Pisani MA, Ely EW, Gifford D, Inouye SK. Detection of delirium in the ICU: Comparison of CAM-ICU with CAM ratings. J Amer Geriatr Soc 2005;53:495-500. PMID:15743296 6. Pisani MA, Redlich CA, McNicoll L, Ely EW, Friedkin R, Inouye SK. Short-term outcomes in older intensive care unit patients with dementia. Crit Care Med 2005; 33:1371-76. PMID:15942358 7. D’Ambrosio C, Stachenfeld NS, Pisani MA, Mohsenin V. Sleep, breathing, and menopause: The effect of fluctuating estrogen and progesterone on sleep and breathing in women. Gender Medicine 2005; 2(4):238-245. PMID: 16464735 8. Friedman LN, Nash ER, Byrant J, Henry S, Shi J, D’Amato, J, Khaled GH, Russi MB, Pisani MA, Edberg SC, O’Conner PG, Cain H, Tanoue L, Weissman, DN. High rate of negative tuberculin and QuantiFERON® tests in individuals with histories of past-positive skin tests. Infect Control Hosp Epidemiol 2006; 27:436-41. PMID:16671022 9. Pisani MA, Araujo KLB, Van Ness PH, Zhang Y, Ely EW, Inouye SK. A research algorithm to improve detection of delirium in the intensive care unit. Crit Care. 2006 Aug 18;10(4):R121. PMID:16919169 10. Cosgriff JA, Pisani MA, Bradley EH, O’Leary JR, Fried TR. The association between treatment preferences and trajectories of care at the end-of-life. J. Gen. Intern. Med. 2007; 22(11):1566-71. PMID:17874168 11. Pisani MA, Murphy TE, Van Ness PH, Araujo KLB, Inouye SK. Admission characteristics associated with delirium in older patients in a medical intensive care unit. Arch Intern Med 2007; 167 (15):1629-1634. PMID:17698685 12. Van Ness PH, Murphy TE, Araujo KLB, Pisani MA, Allore HG. The use of missingness screens in clinical epidemiologic research has implications for regression modeling. J Clin Epi 2007 60(12):1239-45. PMID:17998078 13. Pisani MA, Murphy TE, Araujo KA, Slattum P, Van Ness PH, Inouye SK. Benzodiazepine and opioid use and the duration of ICU delirium in an older population. Crit Care Med, 2009 37(1):177-183. PMID:19050611 14. Pisani MA, Kong SY, Kasl SV, Murphy TE, Araujo KL, Van Ness PH. Days of Delirium are Associated with 1-year Mortality in an Older Intensive Care Unit Population. Am J Respir Crit Care Med 2010 180 (11): 1092-1097. PMID:19745202 15. Pisani MA, Murphy TE, Araujo KA, Van Ness PH. Factors associated with persistent delirium after intensive care unit admission in an older medical patient population. J Crit Care 2010 Sep:25(3): 540 e1-7. PMID:20413252 16. Akgun KM, Murphy TE, Araujo KLB, Van Ness PH, Pisani MA. Equivalent Treatment of Older Medical Intensive Care Unit Patients Based on Gender. Crit Care Res Prac 2010:404608. Epub 2010 Oct 20. PMID:20981259 17. Vest MT, Murphy TE, Araujo KL, Pisani MA. Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health Qual Life Outcomes 2011; Feb 5; 9:9. PMID:21294911 13 Margaret Ann Pisani, M.D., M.P.H. 18. Murphy TE, Van Ness PH, Araujo, KLB, Pisani MA. Bayesian Time Series Analysis of a Repeated Measures Poisson Outcome with Excess Zeroes. Am J Epidemiology, 2011 Dec 1; 174(11):1230-7. PMID:22025357 19. McGinnis K, Brandt C, Skanderson M, Justice A, Shahrir S, Butt AA, Brown S, Freiberg M, Gibert G, Goetz M, Kim JW, Pisani MA, Rimland D, Rodriquez-Barradas M, Sico J, Tindle H, Crothers K. Validating Smoking Data from the Veteran’s Affair Health Factor Dataset, an Electronic Data Source. Nicotine & Tobacco Research Sept 12, 2011. PMID:21911825 20. Van Ness PH, Murphy TE, Araujo KLB, Pisani MA. Multivariate Graphical Methods Provide an Insightful way to Formulate Explanatory Hypotheses from Limited Categorical Data. J Clinical Epi. 2012 Feb; 65(2):179-88. PMID:21889310 21. Pisani MA, Ferrante L. Among patients admitted to ICU, delirium is most common in those with neurological diagnoses, and is associated with adverse health outcomes. Evid Based Nurs. 2012 Nov 21. [Epub ahead of print]. PMID:23171569 22. Akgun KA, Gordon K, Pisani MA, Fried T, McGinnis KA, Tate JP, Butt AA, Gilbert CL, Huang L, Rodriquez-Barradas MC, Rimland D, Justice AC, Crothers K. Risk factors for hospitalization and medical intensive care unit admissions among HIV infected veterans. J Acquir Immune Defic Syndr. 2012 Oct 29. [Epub ahead of print]. PMID:23111572 23. Puchalski JT, Argento AC, Murphy TE, Araujo KLB, Olivia I, Rubinowtiz A, Pisani MA. Etiologies of bilateral pleural effusions. Respir Med. 2013 Feb;107(2):284-91. PMID: 23219348 24. Akgun KA, Tate JP, Pisani MA, Fried T, Butt AA, Gilbert CL, Huang L, Rodriquez-Barradas MC, Rimland D, Justice AC, Crothers K. Medical intensive care unit (MICU) admission diagnoses and outcomes in HIV-infected and uninfected Veterans in the combination antiretroviral era. Crit Care Med. 2013 Mar 15. PMID:23507717 25. Pisani MA, Bramley K, Vest MT, Araujo KLB, Murphy TE. Patterns of benzodiazepine, opiate and antipsychotic drug administration in a medical intensive care unit. Am J Crit Care. 2013 Sep;22(5):e62-e69. PMID:23996429 26. Puchalski JT, Argento AC, Murphy TE, Araujo KLB, Pisani MA. The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013 Aug;10(4):336-41. PMID: 23952852 27. Mannam P, Shinn A, Srivastava A, Neamu R, Walker W, Bohanon M, Merkel J, Kang M, Dela Cruz C, Ahasic A, Pisani M, Trentalange M, West AP, Shadel G, Shen J, Elias J, Lee P. MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1;306(7):L604-19. PMID:24487387 28. Kookoolis A, Puchalski JT, Araujo KL, Murphy TE, Pisani MA. Mortality of hospitalized patients with pleural effusions. J Pulm Respir Med. 2014 Jun;4(3):184. PMID:25977841 29. Knauert MP, Yaggi HK, Redeker NS, Murphy TE, Araujo KL, Pisani MA. Feasibility study of unattended polysomnography in medical intensive care unit patients. Heart Lung. 2014 Sep-Oct;43(5):445-52. Epub 2014 Jul 12. PMID:25023504 30. Goyal G, Pisani MA, Murphy TE, Araujo KL, Puchalski JT. Advanced diagnostic bronchoscopy using conscious sedation and the laryngeal nerve block: tolerability, thoroughness and diagnostic yield. Lung. 2014 Dec;192(6):905-13. Epub 2014 Jun 28. PMID:24972639 31. Hoang, Q, Pisani MA, Inzucchi S, Buqu H, Honiden S. The prevalence of undiagnosed diabetes mellitus and the association of baseline glycemic control on mortality in the intensive care unit: A prospective observational study. J Crit Care. 2014 Dec;29(6):1052-6 Epub 2014 Jun 12. PMID:25092614 32. Ahasic A, Van Ness P, Murphy TE, Araujo KL, Pisani MA. Functional status after critical illness: Agreement between patient and proxy assessments. Age Ageing. 2014 Oct 16. [Epub ahead of print] PMID:25324334 14 Margaret Ann Pisani, M.D., M.P.H. 33. Pisani MA, Araujo KL, Murphy TE. Association of Cumulative Dose of Haloperidol with Delirium in Older Medical Intensive Care Unit Patients. Crit Care Med. 2015 [Epub ahead of print] PMID:25746748 34. Hopper K, Fried T, Pisani MA. Healthcare worker attitudes and identified barriers to patient sleep in the medical intensive care unit. Heart Lung. 2015 Mar-Apr;44(2):95-9. [Epub 2015 Feb 14]. PMID:25686516 35. Ferrante L, Pisani MA, Murphy TE, Gabbauer EA, Leo-Summers L, Gill TM. Functional trajectories among older persons before and after critical illness. JAMA Intern Med. 2015 Feb 9. [Epub ahead of print] PMID:25665067 36. Debiasi EM, Pisani, MA, Murphy TE, Katy KL, Kookoolis A, Argento AC, Puchalski JT. Pleural effusions and mortality at 30-days and 1-year. Eur Respir J. 2015 Apr 2. pii: ERJ02171-2014. [Epub ahead of print] PMID:25837039 37. Barakat L, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgun KM, Goetz MB, Butt AA, Rodriquez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes of HIV-infected and uninfected older men hospitalized with community-acquired pneumonia. HIV Medicine. 2015 May 11 [Epub ahead of print] PMID:25959543 38. Chima-Okereke C, Murphy TE, Araujo KL, Pisani MA. The impact of race on intensity of care provided to older adults in the medical intensive care unit. J Racial Ethnic Health Disparities. In Press 39. Attia EF, McGinnis KA, Feemster LC, Akgun KA, Butt AA, Graber CJ, Fine MJ, Goetz MB, Rodriguez-Barradas M, Pisani MA, Tindle HA, Brown ST, Hoo, GW, Rimland D, Gilbert CL, Huang L, Freiberg MS, Hough CL, Crothers K. Association of COPD with risk for pulmonary infections requiring hospitalization in HIV-infected Veterans. JAIDS. In Press Abstracts (*Oral Presentations) 1. Moslehi F, Ligas JR, Pisani M, Epstein MAF. Wave Mechanics Applications in Respiratory Mechanics. 38th Annual Fall Meeting of the American Physiological Society, 1987. 2. Moslehi F, Ligas JR, Pisani M, Epstein MAF. An Application of Wave Mechanics: Effects of Viscosity and Geometry. FASEB 1988. 3. Epstein MAF, Moslehi F, Pisani M, Ligas JR. One and Two Dimensional Wave Mechanics for Oscillating Flows in Respiration. 6th International Conference on Mechanics in Medicine and Biology, 1988. 4. Moslehi F, Epstein MAF, Ligas JR, Pisani M, Epstein RA. Physiological Flow Impedance as a Fluid Mechanical Field Variable. 10th Annual Conference of the IEEE Engineering in Medicine and Biology Society, 1988. 5. Epstein MAF, Moslehi F, Ligas JR, Pisani M, Epstein RA. Airway Impedance Analysis with Wave Mechanic Models: Effects of Airway Geometry. FASEB. 1989. 6. Epstein MAF, Pisani M, Conard PL, Epstein RA. Airway Acoustic Resonance in Dogs. FASEB Journal. 1990. 7. *Pisani M, Inouye SK. Cognitive impairment in older medical intensive care unit patients: Physician recognition, intensity of care and outcomes. American College of Chest Physicians; Philadelphia, PA. November 2001. 8. *Pisani M, Inouye SK. Preexisting cognitive impairment in older patients admitted to the intensive care unit. Gerontological Society of America; Chicago, IL, November 2001. 9. Pisani MA, Redlich CA, Inouye SK. Detection of preexisting cognitive in a medical ICU using two proxy scales. American Thoracic Society. Am. J. Respir. Crit. Care Med. 2002. 10. *McNicoll L, Pisani M, Zhang Y, Inouye SK. Adverse Hospital Outcomes in Critically Ill Older Patients: The Effect of Delirium. Gerontological Society of America; November 2002. 15 Margaret Ann Pisani, M.D., M.P.H. 11. Pisani M, Ely EW, Redlich CA, McNicoll L, Inouye SK. Favorable outcomes of elderly patients with critical illness and preexisting cognitive impairment. American Geriatrics Society, May 2003. 12. Weissman DN, Khaled G, Nash E, Bryant J, Henry S, Shi J, D'Amato J, Pisani MA, Janotka E, Edberg S, O'Connor P, Russi M , Cain H , Tanoue L and Friedman LN. Does Tuberculin Skin Testing (TST) Boost In Vitro Measures of TB-Specific Cell Mediated Immunity? Am. J. Respir. Crit. Care Med. 2003; 167(7):A866. 13. Pisani MA, Redlich CA, Ely W, McNicoll L, Inouye SK. Favorable ICU outcomes in older patients with preexisting cognitive impairment. Am. J. Respir. Crit. Care Med. 2003; 167(7):A252. 14. *Friedman LN, Khaled G, Nash E, Bryant J, Henry S, Shi J, D’Amato J, Janotka E, Edberg S. O’Connor P, Russi M, Cain H, Pisani M, Tanoue L, Weissman DN. High rate of Tuberculosis Skin Test (TST) reversion in screening programs and its association with the Quantiferon-TB (QFN) assay. Am. J. Respir. Crit. Care Med. 2004; 169(7):A259. 15. *McNicoll L, Pisani MA, Inouye SK. One-year outcomes following delirium in older ICU patients. JAGS 52(4), April 2004, A4. 16. Pisani MA, Araujo K, Zhang Y, Lee P, Redlich CA, Inouye SK. Risk Factors for New-Onset Delirium in Older ICU Patients. American Geriatric Society, May 2004. 17. *Pisani MA, Murphy TE, Araujo KLD, Van Ness PH. Psychoactive medications and the duration of delirium in an ICU population. American Thoracic Society Am. J. Respir. Crit. Care Med. 2007; 175:A21. 18. Pisani MA, Murphy TE, Van Ness PH, Araujo KLB, Inouye SK. Characteristics associated with delirium in patients in a medical intensive care unit. American Thoracic Society Am. J. Respir. Crit. Care Med. 2007; 175:A786. 19. Pisani MA, Van Ness PH, Araujo KLB, Murphy TE. Risk factors for delirium persistence after ICU discharge in an older medical population. Am. J. Respir. Crit. Care Med. 2008; 177:A987. 20. Akgun KM, Araujo KLB, Siner JM, Pisani MA. Association between ICU Delirium and Serum IL-6 Levels. Am. J. Respir. Crit. Care Med. 2008 177:A987. 21. Akgun KM, Araujo KLB, Murphy TE, Pisani MA. Gender Differences in Medical Intensive Care Unit Patients. Am. J. Respir. Crit. Care Med. 2008; 177: A634. 22. Akgun KM, Pisani MA, Butt AA, Gibert CL, Rodriguez-Barradas, MC, Justice AC, Rimland D, Crothers K. Incidence and Mortality of MICU Admission in HIV Infected (HIV+) and NonInfected (HIV-) Veterans. Am. J. Respir. Crit. Care Med. 2010; 181: A5200. 23. Akgun KM, Pisani MA, Fried TR, Butt AA, Gibert CL, Rimland D, Justice AC, RodriguezBarradas, MC, Crothers K. Risk Factors for MICU Admission among HIV+ Patients. Am. J. Respir. Crit. Care Med. 2010; 181: A5199. 24. *Vest M. Araujo KLB, Murphy TE, Pisani MA. Disabilities in activities of daily living and quality of life among older medical ICU survivors. Am. J. Respir. Crit. Care Med. 2010; 181: A5358. 25. Bramley K, Vest M, Araujo KLB, Murphy TE, Pisani MA. Sedative, narcotic and haloperidol drug dosing by nursing shift in a medical ICU. Am. J. Respir. Crit. Care Med. 2010; 181: A4549. 26. Mathur A, Pisani MA, Araujo KLB, Trow T. Risk factors for MICU admission in patients with pulmonary hypertension. Chest 2010; 138: 296A. 27. Argento AC, Pisani MA, Johnson K, Qin L, Puchalski J. Thoracentesis are safe in patients with bleeding tendencies. Am. J. Respir. Crit. Care Med. 2011; 183: A4630. 28. Panico M, Jenq G, Honiden S, Araujo KLB, Pisani MA. Outcomes following a rapid response and the impact on transfer to the intensive care unit. Am. J. Respir. Crit. Care Med. 2011; 183: A4725. 16 Margaret Ann Pisani, M.D., M.P.H. 29. *Heavner J, Pisani MA. Carpal tunnel syndrome and hypoxemia: A case of the antisynthetase syndrome. Am. J. Respir. Crit. Care Med. 2011; 183: A5656. 30. Akgun KM, Pisani M, Fried T, Butt AA, Gibert C, Rimland D, Huang L, Justice AC, Rodriguez-Barradas M, Crothers KA. Impact of age on medical intensive care unit admissions in HIV-infected patients. Am. J. Respir. Crit. Care Med. 2011; 183: A6270. 31. Akgun KM, Tate JP, Pisani M, Butt AA, Gilbert C, Rimland D, Huang L, Justice AC, Rodriquez-Barradas MC, Crothers K. Is the VACS index responsive to acute critical illness? 16th Annual Instructional Workshop on HIV Observational Databases (IWHOD) March 2012 Athens, Greece, Abstract #16_173 32. *Akgun KM, Tate JP, Pisani M. Butt AA, Gibert CL, Rimland D, Huang L, Justice AC, Rodriquez-Barradas MC, Crothers K. Prediction of 30-day mortality after MICU admission among HIV-infected patients. Am. J. Respir. Crit. Care Med. 2012; 185: A2549. 33. Erb CT, Pisani MA, Murphy TE, Araujo KLB, Puchalski JT. The safety, tolerability and outcomes of performing endobronchial ultrasound (EBUS) in obese patients. Am. J. Respir. Crit. Care Med. 2012; 185: A3000. 34. Knauert-Brown MP, Yaggi HK, Redeker NS, Murphy TE, Araujo KLB, Donlon T, Pisani MA. Feasibility of conducting 24-hour polysomnography studies in the medical intensive care unit. Am. J. Respir. Crit. Care Med. 2012; 185: A1617. 35. Knauert-Brown MP, Xu X, Shan P, Qin L, Araujo KLB, Allore HG, Pisani MA, Lee PJ. Alterations in toll-like receptor 4 function secondary to smoking and age. Am. J. Respir. Crit. Care Med. 2012; 185: A1314. 36. Mathews KS, Jenq GY, Siner JM, Long EF, Pisani MA. Short-Stay patients in the intensive care unit: Characterizing patient acuity, throughput and critical care resource utilization. Am. J. Respir. Crit. Care Med. 2012; 185: A6731 37. *Argento AC, Pisani MA, Murphy TE, Araujo KLB, Kookoolis A, Johnson K, Puchalski JT. Impact of thoracentesis on dyspnea and quality of life. Chest 2012; 142:488A 38. Knauert-Brown MP, Yaggi HK, Redeker NS, Murphy TE, Arajuo KLB, Pisani MA. Feasibility of providing medical ICU patients with a four hour nocturnal naptime. Chest 2012; 142:547A. 39. Mathews K, Pisani MA, Jenq GY, Long E. Characterizing the flow of short-stay patients in the intensive care unit. Society for Medical Decision Making October 2012. 40. Mathews K, Jenq GY, Long E, Pisani MA. ICU utilization by “subacute” patients: reasons for admission and opportunities for improvement. Society for Critical Care Medicine January 2013. 41. Ahasic A, Murphy TE, Araujo KLB, Pisani MA. Association between body mass index (BMI) and occurrence of delirium in a cohort of older medical ICU patients. Am. J. Respir. Crit. Care Med. 2013: A40028. 42. Hoang QN, Pisani MA, Inzucchi S, Hu B, Honiden S. The prevalence of previously undiagnosed diabetes and the impact of baseline glycemic control upon outcomes in the medical ICU. Am. J. Respir. Crit. Care Med. 2013: A43818. 43. *Hu X, Puchalski JT, Pisani MA, Carbone C, Michaud GC, Herzog E. Intrathoracic and circulating fibrocytes are elevated in patients with malignant pleural effusions. Am. J. Respir. Crit. Care Med. 2013: A44060. 44. Chima-Okereke C, Murphy TE, Araujo KLB, Pisani MA. Impact of race on the intensity of care provided to older adults in the medical intensive care unit. Am. J. Respir. Crit. Care Med. 2013: A37967. 45. Knauert M, Yaggi HK, Redeker NS, Pisani MA. Medical ICU sleep deprivation: frequent nocturnal room activity. Annual Meeting of the Associated Professional Sleep Societies. June 2013: A0815 17 Margaret Ann Pisani, M.D., M.P.H. 46. Murphy E, Pisani MA, Murphy TE, Araujo KL, Kookoolis A, Argento AC, Puchalski JT. Pleural effusions and 30-day mortality. Chest 2013. 47. *Ahasic A, Murphy TE, Araujo KL, Pisani MA. Functional assessment after critical illness. Agreement between patient and proxy assessments. Chest 2013. 48. *Erb C, Pisani MA, Puchalski JT. The Utility of a Silicone Y-Stent in the Secondary Carina for a Life-Altering Bronchoesophageal Fistula. Chest 2013. 49. *Bramley K, Pisani MA, Puchalski JT. Electrocautery knife incisions during EBUS-guided miniforceps biopsies. Chest October 2013. 50. *Ryu C, Bramley, K, Boffa D, Pisani MA, Puchalski JT. Endobronchial treatment of pulsatile hemoptysis complicating Y-stent management of tracheobronchomalcia. Case Report. Chest 2013. 51. Akgun KM, Tate JP, Pisani M, Butt AA, Gibert C, Fried T, Rimland D, Huang L, Justice AC, Rodriquez-Barradas MC, Crothers K. Hospital readmission and incident skilled nursing facility placement in MICU survivors from a nationally representative cohort of HIV-infected and uninfected veterans: 1996-2010. Am. J. Respir. Crit. Care Med. 2014: A4518. 52. *Ferrante L, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers L, Gill TM. The course of disability in the year immediately before and after an ICU admission in older persons. Am. J. Respir. Crit. Care Med. 2014: 3931. 53. *Ferrante L, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers L, Gill TM. The association between pre-ICU functional trajectory and mortality after ICU admissions in older persons. Am. J. Respir. Crit. Care Med. 2014: 3934. 54. *McGinniss JE, Wong Y, Shinn AA, Bohanon M, Merkel J, Ahasic AA, Pisani MA, Lee PJ, Mannam P. MAP Kinase Kinase 3 (MKK3) Regulates Mitochondrial Turnover And Susceptibility to Sepsis. Am. J. Respir. Crit. Care Med. 2014: A3939. 55. Knauert MP, Jeon S, Pisani MA, Yaggi HK, Redeker NA. Noise as a source of medical intensive care unit sleep disruption. Sleep 2014 56. Rowe T, Araujo KL, Van Ness PH, Pisani MA, Juthani-Mehta M. Outcomes of Older Adults with Sepsis at Admission to an Intensive Care Unit. Infectious Disease Society of America Oct 10, 2014, A46058. 57. Ramaswamy A, Homer R, Killam J, Pisani MA, Murphy TE, Araujo K, Puchalski JT. Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Lung Disease. Am. J. Respir. Crit. Care Med. 2015; 191:A3727 58. Ramaswamy A, Jin L, Zhang B, Hu B, Bramley K, Boffa D, Pisani, MA, Puchalski JT, Takyar S. MiR-1 Levels in Lung Tumor Samples Correlate with Tumor Progression in Human Non-Small Cell Lung Cancer Patients Am. J. Respir. Crit. Care Med. 2015; 191:A5095 59. Ferrante L, Pisani MA, Murphy TE, Gill T. Factors Associated With Functional Recovery After Critical Illness in Older Persons. Am. J. Respir. Crit. Care Med. 2015; 191:A2282 60. Ahasic AM, Murphy TE, Araujo KL, Pisani MA. Obesity and Persistent Delirium: Is There an Association? Am. J. Respir. Crit. Care Med. 2015;191:A4016 61. Ahasic AM, Murphy TE, Araujo KL, Pisani MA. Predictors of Change in Functional Status of Older Patients Before and After Intensive Care Unit Admission. Am. J. Respir. Crit. Care Med. 2015; 191:A2283 62. Pinto S, Pisani MA, Araujo KL, Argento C, Kookoolis, A, Puchalski JT. Impact of Endobronchial Ablation Therapy and Airway Stenting on Dyspnea and Activities of Daily Living in Patients with Central Airway Obstruction. Am. J. Respir. Crit. Care Med. 2015; 191: A3721 63. Akgun KA, Cheung K, Crothers K, Pisani MA, Justice AC, Gilbert CL, Friedberg M, Brandt C, Fried T. Identifying Medical Intensive Care Unit (MICU) Palliative Care Domains with Chart Review. Am. J. Respir. Crit. Care Med. 2015; 191:A4552 18 Margaret Ann Pisani, M.D., M.P.H. 64. Erb C, Fares WH, Araujo KA, Murphy TE, McDade KE, Pisani MA, Puchalski JT. A modified approach to the use of ultrasound for subclavian vein catheterization. Am. J. Resp. Crit. Care Med. 2015; 191:A5681 65. *Han L, Allore HG, Araujo KL, Pisani MA. Anticholinergic drug burden and severity of delirium symptoms among older medical patients receiving intensive care. Gerontological Society of America 2015 Accepted Chapters, Book and Reviews Chapters 1. Levy CR, Pisani MA, Ely EW. Pulmonary and Critical Care Among Elderly Patients Admitted to the Intensive Care Unit. In: Chest Medicine, eds. George RB, Light RW, Matthay MA, Matthay RA. May 2005 Publisher: Williams & Wilkins. 2. Pisani MA, Ely EW. Monitoring and Treatment of Pain, Anxiety and Delirium in the ICU. In: Clinical Critical Care Medicine, eds. Albert RK, Slutsky A, Ranieri M, Takala J, Torres A. 2006 Publisher: Elsevier, Philadelphia, PA. 3. Pisani MA, Ely EW. Respiratory Diseases and Disorders. In: Pacala JT, Sullivan GM, eds. Geriatric Review Syllabus: A core Curriculum in Geriatric Medicine, 7th ed. New York, NY: American Geriatrics Society; 2010 4. Pisani MA, Ely EW. Respiratory Diseases and Disorders. In: Flaherty E, Resnick B, eds. Geriatric Nursing Review Syllabus: A Core Curriculum in Advanced Practice Geriatric Nursing. 3rd ed. NY: American Geriatrics Society; 2011 5. Mathur A, Sauler M, Pisani MA. Pulmonary Embolism in Older Patients. In: Aging and Lung Disease, ed. Pisani MA. 2012 Publisher: Springer, Humana Press, New York, NY. 6. Pisani MA. Delirium Assessment Tools. In: Current Concepts in Adult Critical Care, eds. Cheng EY, Park PK. February 2012, Society for Critical Care Medicine. 7. Akgun KA, Pisani MA. Respiratory Diseases and Disorders. In: Durso SC, Sullivan GM, eds. Geriatric Review Syllabus: A Core Curriculum in Geriatric Medicine, 8th ed. New York, NY: American Geriatrics Society; 2013 8. Pisani MA. Delirium and Dementia: Unraveling the Complex Relationship. In: Brain Dysfunction in Critical Illness, eds. Stevens R, Sharshar T, Ely EW. Publisher: Cambridge University Press; 2013 9. Farshidpanah S, Pisani MA, Ely EW, Watson PL. Sleep in the critically ill patient. In: Principles and Practice of Sleep Medicine 6th edition, eds. Meir Kryger. Publisher Elsevier; 2015 10. Knauert M, Haspell J, Pisani MA. Sleep loss and circadian disruption in the ICU. In: Advances and challenges in critical care, eds. Shyoko Honiden, Jonathan Siner. Publisher Elsevier; In Press 11. Akgun KA, Pisani MA. Respiratory Diseases and Disorders. In: Durso SC, Sullivan GM, eds. Geriatric Review Syllabus: A Core Curriculum in Geriatric Medicine, 9th ed. New York, NY: American Geriatrics Society; In Press 12. Oldham M, Pisani MA. Sedation in critically ill patients. In: Sleep and circadian rhythms in the ICU, Critical Care Clinics, eds. Vipin Malik, Teofilo Chung. Publisher Elsevier; In Press 13. Pisani MA, Ferrante L. Intensive care unit outcomes in older adults. In: Lung and aging monograph. PMID:26118921 In Press 14. Debiasi E, Akgun KA, Pisani MA. Awake or sedated; Trends in the evaluation and management of agitation in the intensive care unit. In: Seminars in Respiratory and Critical Care Medicine, eds. Mark Siegel, Wassim Fares. Publisher Thieme; In Press 19 Margaret Ann Pisani, M.D., M.P.H. Books 15. Pisani MA. Guest Editor: Respiratory Disease in Older Patients. Clinics in Chest Medicine. 2007, 28 (4). Publisher: Elsevier, Philadelphia, PA. 16. Pisani MA. Editor: Aging and Lung Disease: A Clinical Guide. Respiratory Medicine Series. 2012, Publisher: Springer, Humana Press, New York, NY. Reviews 17. Pisani M, McNicoll L, Inouye SK. Cognitive impairment in the intensive care unit. Clinics in Chest Medicine 2003; 24(4): 727-738. PMID:14710700 18. Pisani MA. Recognition of preexisting cognitive impairment in older intensive care unit patients. Research and Practice in Alzheimer’s Disease 2004; 9: 33-38. 19. Siner J, Pisani MA. Mechanical Ventilation and Acute Respiratory Distress Syndrome in Older Patients. Clinics in Chest Medicine, 2007 Dec;28(4):783-91. PMID:17967294 20. Pisani MA. Delirium in the ICU: An Overview. Pulmonary and Critical Care Updates. Volume 22, Lesson 17 2008. 21. Pisani MA. Considerations in Caring for the Critically Ill Older Patient. J Intensive Care Med, 2009, 24(2):83-95. PMID:19114416 22. Pisani MA. Intensive and Critical Care Medicine. JAMA 2010; 304: 1497. 23. Akgun KM, Pisani MA, Crothers K. The changing epidemiology of HIV-infected patients in the intensive care unit. J Intensive Care Med. 2011 May-Jun;26(3):151-64. PMID:21436170 24. Akgun KM, Huang L, Morris A, Justice AC, Pisani MA, Crothers K. Critical illness in HIVinfected patients in the era of combination antiretroviral therapy. Proc. Am. Thorac. Soc 2011 Jun;8(3):301-7. PMID:21653532 25. Akgun KM, Crothers K, Pisani MA. Epidemiology and management of common pulmonary diseases in older persons. J Gerontol A Biol Sci Med Sci. 2012 Mar;67(3):276-91. PMID:22337938 26. Jones S, Pisani MA. Intensive Care Unit Delirium: An Update. Curr Opin Crit Care. 2012 Apr;18(2):146-51. PMID:22322260 27. Pisani MA, Friese RS, Gehlbach BK, Schwab RJ, Weinhouse GL, Jones SF. Sleep in the ICU: A concise clinical review. Am J Resp Crit Care Med. 2015 Apr 1;191(7):731-38. [Epub ahead of print] PMID:25594808 Peer-Reviewed Educational Materials 28. Pisani MA. American College of Chest Physicians Pulmonary and Critical Care Updates. “Delirium in the ICU: An Overview”. Volume 22, Lesson 17. September 2008 29. Pisani MA. British Medical Journal. “Delirium Monograph”. 2013, 2014 Invited Editorials and Commentaries 30. Pisani MA. Delirium assessment in the intensive care unit: patient population matters. Crit Care. 2008 Apr 7; 12(2):131. PMID:18423059 31. Pisani MA. Sleep in the Intensive Care Unit: An Oft-Neglected Key to Health Restoration. Heart Lung. 2015 Mar-Apr;44(2):87. Epub 2015 Feb 10. PMID:25680805 Scholarship in Progress 1. Ahasic A, Murphy TE, Araujo KL, Pisani MA. Association between body mass index (BMI) and occurrence of delirium in a cohort of older medical ICU patients. In preparation. 2. Matthews KS, Jenq GY, Long EF, Pisani MA. 24 Hours or Less: Clinical Characteristics of Short Stay Patients in the Intensive Care Unit. Submitted. 3. Rowe T, Araujo KL, Van Ness PH, Pisani MA, Juthani-Mehta, M. Outcomes of older adults with sepsis at admission to an intensive care unit. Submitted. 20 Margaret Ann Pisani, M.D., M.P.H. 4. Bramley K, Pisani, MA, Murphy TE, Katy KL, Homer R, Puchalski JT. EBUS-guided cautery-assisted forceps biopsies: improved yield, expanded applications. Under Revision. 5. Farrokh S, Heavner M, Pisani MA. Characterization of atypical antipsychotic prescribing practices in the treatment of intensive care unit delirium. Submitted. 6. Ding Q, Redeker NS, Pisani MA, Yaggi HK, Knauert M. Environmental stressors impacting patient’s sleep in the intensive care unit: patient, family and clinical staff perceptions. Submitted. 21