Download Professor J R Parratt

Professor J R Parratt
Publications
PUBLISHED PAPERS
Parratt JR, West GB 5-hydroxytryptamine and tissue mast cells J Physiol (1957), 137, 169178
Parratt JR, West GB Release of 5-hydroxytryptamine and histamine from tissues of the rat
J Physiol (1957), 137, 179-192
Parratt JR, West GB 5-hydroxytryptamine and the anaphylactoid reaction in the rat
Physiol (1957), 139, 27-41
J
West GB, Parratt JR 5-hydroxytryptamine and the skin Arch Dermatol (1957), 76, 336-342
Parratt JR, West GB Histamine liberation in the hamster Arch int Pharmacodyn
113, 209-216
(1957),
Parratt JR, West GB The relationship of 5-hydroxytryptamine to capillary permeability in
the skin of the rat J Physiol (1958), 140, 105-112
Parratt JR, West GB Inhibition by various substances of oedema formation in the hind-paw
of the rat induced by 5-hydroxytryptamine, histamine, dextran, egg white and compound
48/80 Br J Pharmacol (1958), 13, 65-70
Parratt JR, West GB Hypersensitivity and the thyroid gland Int Archiv Allergy (1960), 16,
288-302
Foy JM, Parratt JR A note on the presence of noradrenaline and 5-hydroxytryptamine in
plantain (Musa sapientum, var paradisiaca) J Pharm Pharmacol (1960) 12, 360-364
Foy JM, Parratt JR 5-hydroxytryptamine in pineapples J Pharm Pharmacol (1961), 13, 382383
Foy JM, Parratt JR Urinary excretion of 5-hydroxyindoleacetic acid in West Africans Lancet
(1962), 1, 942-943
Grayson J, Parratt JR The effect of bradykinin on blood flow and heat production in the
myocardium Experientia (1963), 19, 161-162
Parratt JR A comparison of the effects of the plasma kinins, bradykinin and kallidin, on
myocardial blood flow and metabolism Brit J Pharmacol (1964), 22, 34-46
Parratt JR Vasopressor responses to kallidin, bradykinin and eledoisin in hypotensive rats J
Pharm Pharmacol (1964), 16, 132-133
Grayson J, Parratt JR Observations of blood flow in the myocardium Acta Anatomica
(1965), 7, 416-424
Parratt JR Blockade of sympathetic beta-receptors in the myocardial circulation Brit J
Pharmacol (1965), 24, 601-611
Lochner W, Parratt JR A comparison of the effects of locally and systemically administered
kinins on coronary blood flow and myocardial metabolism Brit J Pharmacol, (1966), 26, 1726
Ojo GO, Parratt JR Urinary excretion of 5-hydroxyindoleacetic acid in Nigerians with
endomyocardial fibrosis Lancet, (1966), i, 854-856
Grayson J, Parratt JR A species comparison of the effects of changing perfusion pressure on
blood flow and metabolic heat production in the myocardium J Physiol (1966), 187, 465-489
Grayson J, Parratt JR A pharmacological study of the sympathetic innervation of the
myocardial vascular bed Biblio Anatomica (1966), 9, 363-367
Grayson J, Irvine M, Parratt JR The effects of amyl nitrite inhalation on myocardial blood
flow and metabolic heat production Brit J Pharmacol (1967), 30, 488-496
Parratt JR Propranolol Lancet, ii, (1967) 947-948
Parratt JR Adrenergic receptors in the coronary circulation American Heart Journal (1967)
73, 137-140
Parratt JR The effect of adrenergic neurone blockade on the myocardial circulation Brit J
Pharmacol (1967), 31, 513-522
Grayson J, Irvine M, Parratt JR, Cunningham J Vasospastic elements in myocardial
infarction following coronary occlusion in the dog Cardiovasc Res (1968), 2, 54-62
Parratt J R The effect of adrenaline, noradrenaline and propranolol on myocardial blood
flow and metabolic heat production in monkeys and baboons Cardiovasc Res (1969), 3, 306314
McInnes L, Parratt JR Studies on the mode of action of hexobendine, a prospective antianginal drug Brit J Pharmac (1969), 37, 272-282
Parratt JR The effects of histamine on the myocardial circulation Eur J Pharmacol (1969), 6,
203-208
Parratt JR, Wadsworth, RM Myocardial and haemodynamic effects of the beta-receptor
blocking drug alprenolol (H56/28 in anaesthetised cats Brit J Pharmac (1969) 37, 357-366
Ledingham IMcA, McBride TI, Parratt JR, Vance, JP Changes in myocardial blood flow and
oxygen consumption during exposure to hyperbaric oxygen and hypercarbia in the normal
and ischaemic myocardium In:- Proceedings of the 4th International Congress on Hyperbaric
Medicine Ed J Wada & T Iwa, Igaku Shoin Ltd, Tokyo (1970) p239-241
Parratt JR, Wadsworth R M The effect of catecholamine infusions on myocardial blood flow,
heat production and on general haemodynamics, before and after alprenolol (H56/28) in
anaesthetised cats Brit J Pharmac (1970), 38, 554-571
Parratt JR, Wadsworth RM The effect of 'selective' beta-adrenoreceptor blocking drugs on
the myocardial circulation Brit J Pharmac (1970) 39, 296-308
Ledingham IMcA, McBride TI, Parratt JR, Vance JP The effect of hypercapnia on
myocardial blood flow and metabolism J Physiol Lond (1970), 210, 87-105
Ledingham I McA, Parratt JR, Vance JP Myocardial vascular effects of hyperbaric oxygen in
dogs subjected to haemorrhage In:- 6th Europ Conf Microcirculation, Aalborg 1970, Karger
Basel (1971) p282-285
Grayson J, Irvine M, Parratt JR Effects of carbochromen and dipyridamole on blood flow and
heat production in the dog myocardium before and after acute coronary ligation Cardiovasc
Res (1971) 5, 41-47
Das PK, Parratt JR Myocardial and haemodynamic effects of phentolamine Brit J Pharmac
(1971) 41, 437-444
Parratt JR, Winslow E The cardiovascular pharmacology of quazodine (MJ-1988), with
especial reference to effects of myocardial blood flow and metabolic heat production Brit J
Pharmac (1971) 42, 193-204
Ledingham IMcA, Parratt JR, Vance JP Haemodynamic and myocardial effects of hyperbaric
oxygen in dogs subjected to haemorrhage Cardiovasc Res (1971), 5, 277-285
Vance JP, Parratt JR, Ledingham I McA The effects of hypoxia on myocardial blood flow
and oxygen consumption: Negative role of beta adrenoreceptors Clin Sci (1971) 41, 257-273
Parratt JR, Winslow E Actions of quazodine (MJ1988) on smooth muscle Brit J Pharmac
(1971), 43, 612-623
Parratt JR, Ledingham I McA Experimental infarction in the dog: Changes in blood flow
and in oxygen extraction induced by oxyfedrine in areas of developing myocardial ischaemia
J Pharm Pharmac, (1971) 23, 201-207
Parratt JR, Winslow E Haemodynamic and coronary effects of quazodine in cats with
developing myocardial infarcts J Pharm Pharmac (1972) 24, 673-680
Parratt JR, Wadsworth RM The effects of dipyridamole on the myocardial vasodilator
actions of noradrenaline, isoprenaline and adenosine Br J Pharmac (1972) 46, 585-593
Parratt JR, Wadsworth R M The effects of dipyridamole on coronary post-occlusion
hyperaemia and on myocardial vasodilatation induced by systemic hypoxia Br J Pharmac
(1972) 46, 594-601
Parratt J R Myocardial and circulatory effects of E coli endotoxin; modification of responses
to catecholamines Br J Pharmac (1973) 47, 12-25
Hutton L, Parratt JR, Lawrie TDV Cardiovascular effects of prostaglandin E in experimental
myocardial infarction Cardiovasc Res (1973) 7, 149-155
Mackenzie JE, Parratt JR Effects of oxyfedrine on isolated portal vein and other smooth
muscles Br J Pharmac (1973) 47, 827
Parratt JR, Ledingham IMcA, McArdle CS Effect of a coronary vasodilator drug
(carbochromen) on blood flow and oxygen extraction in acute myocardial infarction
Cardiovasc Res (1973) 7, 401-407
Moore G, Parratt JR Effect of noradrenaline and isoprenaline on blood flow in the acutely
ischaemic myocardium Cardiovasc Res (1973) 7, 446-457
Marshall RJ, Parratt JR The effect of noradrenaline on blood flow and oxygen consumption
in normal and ischaemic areas of myocardium Amer Heart J (1973) 86, 653-662
Marshall RJ, Parratt JR The effect of dipyridamole on blood flow and oxygen handling in the
acutely ischaemic and normal canine myocardium Br J Pharmacol (1973) 49, 391-399
Marshall RJ, Parratt JR, Ledingham IMcA The effect of hyperbaric oxygen (2ATA) on
myocardial blood flow and oxygen consumption in normal and ischaemic areas of the
myocardium after acute coronary artery ligation in the dog In Proceedings of the 5th
International Hyperbaric Congress Edited by WG Trapp, EW Banister, AJ Davison and PA
Trapp Vancouver, Simon Frazer University (1974) 2, 699-711
Marshall RJ, Parratt JR The effect of dilazep on blood flow and oxygen handling in the early
stages of canine myocardial infarction: simultaneous comparison with changes in the normal
myocardium Naunyn-Schmiedeberg's Archiv Pharmacol (1974), 281, 427-436
Marshall RJ, Parratt JR Reduction in ventricular arrhythmias following acute coronary artery
ligation in the dog after the administration of creatine phosphate Naunyn-Schmiedeberg's
Archiv Pharmacol (1974) 281, 437-441
Parratt JR, Winslow E The haemodynamic effects of quazodine, a cardiac stimulant, in
experimental E coli endotoxin shock in the cat Clinical and Experimental Pharm Physiol
(1974) 1, 31-42
Parratt JR, Sturgess R The effect of indomethacin on the cardiovascular and metabolic
responses to E coli endotoxin in the cat Br J Pharmacol (1974) 50, 177-184
Marshall RJ, Parratt JR Changes in blood flow and oxygen consumption in normal and
ischaemic regions of the myocardium following acute coronary artery ligation Cardiovasc
Res (1974), 8, 204-215
Parratt JR, Marshall RJ The response of isolated cardiac muscle to acute anoxia: protective
effect of adenosine triphosphate and creatine phosphate J Pharm Pharmacol (1974) 26, 427433
Marshall RJ, Parratt JR Drug-induced changes in blood flow in the acutely ischaemic canine
myocardium: relationship to subendocardial driving pressure Clin Exper Pharmacol
Physiol (1974) 1, 99-112
Parratt JR The haemodynamic effects of prolonged oral administration of oxyfedrine, a
partial agonist at beta-adrenoceptors: comparison with propranolol Br J Pharmacol (1974)
51, 5-13
Parratt JR, Marshall RJ, Ledingham IMcA Zur Beeinflussung von Stromungeschwindigkeit
und Sauerstoffextraction im ischamischen Myokard Die Medizinische Welt, (1974), 25,
1152-1155
Parratt JR, Sturgess RM E coli endotoxin shock in the cat; treatment with indomethacin Br J
Pharmac (1975), 53, 485-488
Marshall RJ, Parratt JR Antiarrhythmic, haemodynamic and metabolic effects of 3a-amino5a-androstan-2b-ol-17-one hydrochloride in greyhounds following acute coronary artery
ligation Br J Pharmac (1975), 55, 359-368
Parratt JR, Sturgess RM
The effects of the repeated administration of sodium
meclofenamate, an inhibitor of prostaglandin synthetase, in feline endotoxin shock
Circulatory Shock (1975), 2, 301-310
Abaitey AK, Parratt JR Cardiovascular effects of diethylcarbamazine citrate Br J Pharmac
(1976) 56, 219-228
Marshall RJ, Parratt JR Comparative effects of propranolol and practolol in the early stages
of experimental canine myocardial infarction Br J Pharmac (1976) 57, 295-303
Parratt JR, Sturgess RM The effect of a new anti-inflammatory drug, flurbiprofen, on the
respiratory, haemodynamic and metabolic responses to E. coli endotoxin shock in the cat.
Br. J. Pharmac (1976) 58, 547-551
Marshall RJ, Parratt JR The haemodynamic and metabolic effects of MG 8926, a prospective
antidysrhythmic and antianginal agent. Br J Pharmac (1977) 59, 311-322.
Mackenzie, JE & Parratt, JR Comparative effects of glyceryl trinitrate on venous and arterial
smooth muscle Br J Pharmac (1977) 60, 155-160
Parratt, JR & Sturgess, RM The possible roles of histamine, 5-hydroxytryptamine and
prostaglandin PGF2a as mediators of the acute pulmonary effects of endotoxin Br J Pharmac
(1977) 60, 209-219
Abaitey, AK & Parratt, JR The effects of diethylcarbamazine citrate on smooth muscle J
Pharm Pharmacol (1977) 29, 428-432
Moore, GE & Parratt, J R The effects of distension of the small intestine on myocardial
blood flow in anesthetised cats: possible relevance to coronary vasospasm Basic Res Cardiol
(1977) 72, 437-443
Al-Kaisi, N, Parratt, JR, Siddiqui, HH & Zeitlin, I J Feline endotoxin shock: Effects of
methylprednisolone on kininogen-depletion on the pulmonary circulation and on survival
BrJ Pharmac (1977) 60, 471-476
Marshall, RJ & Parratt, JR The antidysrhythmic aminosteroid, ORG 6001, reduces the STsegment elevation produced by coronary occlusion in the dog Br J Pharmac (1977) 61, 315317
Marshall, RJ & Parratt, JR A comparative study of beta-adrenoceptor blocking agents on
blood flow and metabolism in the acutely ischaemic myocardium Proc Royal Soc Med
(1977), 70, Suppl 11, 62-68
Parratt JR & Marshall RJ Are prostaglandins involved in the regulation of coronary blood
flow? A review of the evidence Acta biol med Germ (1978) 37, 747-754
Marshall RJ & Parratt JR The effects of disopyramide phosphate on early post-coronary
artery ligation dysrhythmias, and on epicardial ST-segment elevation, in anaesthetised dogs
Br J Pharmac (1979) 66, 241-250
McCaig DJ, Kane KA, Bailey G, Millington PF & Parratt JR Myocardial function in feline
endotoxin shock: a correlation between myocardial contractility, electrophysiology and
ultrastructure Circulat Shock (1979) 6, 201-211
Kane KA, McDonald FM & Parratt JR The effect of the aminosteroid, Org 6001, on
hypothermia-induced ventricular fibrillation in the cat Br J Pharmac (1979) 66, 609-618
McCaig, D & Parratt, JR The cardiovascular pharmacology of 7-propyltheophyllinedopamine (D4975); comparison with dopamine and dobutamine Br J Pharmac (1979) 67,
239-245
McCaig DJ & Parratt JR Haemodynamic effects of the carboxylic ionophore monensin when
administered before and during shock induced by E coli endotoxin J Pharmac Pharmacol
(1979) 31, 583-587
McCaig DJ & Parratt JR Failure of exogenous ATP and creatine phosphate to modify the
course of E coli endotoxin shock in the cat Circulat Shock (1979) 6, 235-244
Al-Jibouri, Layla, M, Furman, B & Parratt, JR
Blockade of adrenaline-induced
hyperglycaemia in the anesthetized cat by continuous infusion of phentolamine and
propranolol Br J Phamac (1980) 68, 461-466
McCaig, D & Parratt, JR A comparison of the cardiovascular effects of dobutamine and a
new dopamine derivative (D4975) during shock induced by E coli endotoxin Br J Pharmac
(1980) 69, 651-656
McCaig, D & Parratt, JR Reduced myocardial response to calcium during endotoxin shock in
the cat Circulatory Shock (1980) 7, 23-30
Clark, C, Foreman, MI, Kane, KA, McDonald, FM & Parratt, JR Coronary artery ligation in
anaesthetized rats as a method for the production of experimental dysrhythmias and for the
determination of infarct size J Pharmacol Methods (1980) 3, 357-368
Marshall, RJ & Parratt, JR Prophylactic lignocaine and early post-coronary artery occlusion
dysrhythmias in anaesthetised greyhounds Br J Pharmac (1980) 71, 597-600
Kane, KA, Lepran, I, McDonald, FM, Parratt, JR & Szekeres, L The effects of prolonged oral
administration of a new antidysrhythmic drug (Org 6001) on coronary artery ligation
dysrhythmias in conscious and anaesthetised rats J Cardiovasc Pharmacol (1980) 2, 411423
Marshall, RJ & Parratt, JR The early consequences of myocardial ischaemia and their
modification J Physiologie (Paris) (1980) 76, 699-715
Parratt, JR, Marshall, RJ & Ledingham I McA Interventions for improving blood flow,
oxygen availability and the balance between oxygen supply and demand in the acutely
ischaemic myocardium J Physiologie (Paris) (1980) 76, 791-803
Adeleye GA, Al-Jibouri L, Furman BL, Parratt JR Endotoxin-induced metabolic changes in
the conscious, unrestrained rat: hypoglycaemia and elevated blood lactate concentrations
without hyperinsulinaemia Circulat Shock (1981) 8, 543-550
Parratt JR Oxyfedrine as an antianginal drug Lancet (1981) i, 441
Coker, SJ, Marshall, RJ, Parratt, JR & Zeitlin, IJ Does the local myocardial release of
prostaglandins E2 and F2a contribute to the early consequences of acute myocardial
ischaemia? J Mol Cell Cardiol (1981) 13, 425-434
Coker SJ, Parratt JR Prostacyclin-induced changes in coronary blood flow and oxygen
handling in the normal and acutely ischaemic canine myocardium Basic Res Cardiology
(1981) 76, 457-462
Coker, SJ, Ledingham, IM, Parratt, JR & Zeitlin, IJ Aspirin inhibits the early myocardial
release of thromboxane B2 and ventricular ectopic activity following acute coronary artery
occlusion in dogs Br J Pharmac (1981) 72, 593-595
Coker, SJ, Parratt, JR , Ledingham IMcA & Zeitlin, IJ Thromboxane and prostacyclin release
from ischaemic myocardium in relation to arrhythmias Nature (1981), 291, 323-324
Parratt, JR & MacKenzie, JE Possible mechanisms of action of oxyfedrine as an antianginal
drug Br J Clin Pharmacol (1981) 11, 307-308
Campbell C, Parratt JR Which properties of beta-adrenoceptor blocking drugs are important
in the prevention of early post-infraction dysrhythmias? Br J Pharmac (1981) 74, 195-196
Coker, SJ & Parratt, JR The effects of prostaglandins PGE2, PGF2a, prostacyclin,
flurbiprofen and aspirin on arrhythmias resulting from coronary artery ligation in
anaesthetised rats Br J Pharmac (1981) 74, 155-159
Fagbemi, O & Parratt, JR Suppression by orally-administered nifedipine, nisoldipine and
niludipine of early life-threatening ventricular arrhythmias resulting from acute myocardial
ischaemia Br J Pharmac (1981) 74, 12-14
Fagbemi, O & Parratt, JR Calcium antagonists prevent early post-infarction ventricular
fibrillation Eur J Pharmac (1981) 75, 179-186
Hughes B, Madan BR, Parratt JR, Polymyxin B sulphate protects cats against the
haemodynamic and metabolic effects of E coli endotoxin Br J Pharmac (1981) 74, 701-708
Fagbemi, O, Kane, KA & Parratt, JR Creatine phosphate suppresses ventricular arrhythmias
resulting from coronary artery ligation J Cardiovasc Pharmacol (1982) 4, 53-58
Kane, KA, McDonald, FM, Parratt, JR, Timmer, C & Vink, J Antiarrhythmic effects of Org
6001 in rats; correlation with plasma and tissue drug concentrations Br J Pharmac (1982) 75,
319-323
Fagbemi, O, Lepran, I, Parratt, JR & Szekeres, L Naloxone inhibits early arrhythmias
resulting from acute coronary ligation Br J Pharmac (1982) 76, 504-506
Coker, SJ, Fagbemi, O & Parratt, JR Lidoflazine in the early stages of acute myocardial
ischaemia Br J Pharmac (1982) 76, 347-354
Coker, SJ, Parratt, JR, Ledingham, IMcA & Zeitlin, IJ Evidence that thromboxane
contributes to ventricular fibrillation induced by reperfusion of the ischaemic myocardium J
Mol Cell Cardiol (1982) 14, 483-485
Coker, SJ & Parratt, JR Effects of dazoxiben on arrhythmias and ventricular fibrillation
inducd by coronary artery occlusion and reperfusion in anaesthetized greyhounds Br J Clin
Pharmac (1983) 15, 87-96S
Ball, HA, Parratt, JR & Zeitlin, IJ Effect of dazoxiben, a specific thromboxane synthetase
inhibitor, on the pulmonary response to Ecoli endotoxin in anaesthetized cats Br J Clin
Pharmac (1983) 15, Suppl 1, 127-132S
Coker, SJ, Hughes, B, Parratt, JR, Rodger, IW & Zeitlin, IJ The release of prostanoids during
the acute pulmonary response to Escherichia coli endotoxin in anaesthetized cats Br J
Pharmac (1983) 78, 561-570
Fagbemi, O, Kane, KA, Lepran, I, Parratt, JR & Szekeres, L Antiarrhythmic actions of
meptazinol, a partial agonist at opiate receptors, in acute myocardial ischaemia Br J Pharmac
(1983) 78, 455-460
Coker, SJ & Parratt, JR Nifedipine reduces arrhythmias but does not alter prostanoid release
during coronary artery occlusion and reperfusion in anaesthetized greyhounds J Cardiovasc
Pharmac (1983) 3, 406-417
Parratt, JR & Coker, SJ Cardioprotection with calcium antagonists by suppression of early
ischaemic and reperfusion-induced arrhythmias Eur Heart J (1983) 4, (Suppl C) 49-54
Coker, SJ & Parratt, JR Prostacyclin-antiarrhythmic or arrhythmogenic? Comparison of the
effects of intravenous and intracoronary prostacyclin and ZK 36374 during coronary artery
occlusion and reperfusion in anaesthetised greyhounds J Cardiovasc Pharmacol 1983) 5, 557567
Parratt, JR Pharmacological agents to aid the clinician in combating myocardial ischaemia
Eur Heart J (1983) 4, (Supl D), 91-99
Campbell, CA, & Parratt, JR The effect of beta-adrenoceptor blocking agents, with differing
ancillary properties, on the arrhythmias resulting from acute coronary artery ligation in
anaesthetised rats Br J Pharmac (1983) 79, 939-946
Parratt JR, Udvary E The effect of exaprolol (MG 8823) on epicardial ST-segment changes in
a feline model for acute myocardial ischaemia Br J Pharmac (1983) 80, 95-105
Ball HA, Parratt JR, Rodger IW The effect of a selective 5-HT2 antagonist, ketanserin, on the
pulmonary responses to Escherichia coli endotoxin Br J Pharmac (1983) 80, 296-301
Fagbemi O, Kane KA, McDonald FM, Parratt JR, Rothaul AL The effects of verapamil,
prenylamine, flunarizine, and cinnarizine on coronary artery occlusion-induced arrhythmias
in anaesthetised rats Br J Pharmacol (1984), 83, 299-304
Coker SJ, Parratt JR The effects of nafazatrom on arrhythmias and prostanoid release during
coronary artery occlusion and reperfusion in anaesthetised greyhounds J Mol Cell Cardiol
(1984) 16, 43-52
Parratt JR, Sharma N, Zeitlin IJ Prostaglandins and thromboxane in the delayed phase of
shock induced by Serratia marcescens endotoxin Br J Pharmac (1984) 82, 281-288
Campbell CA, Parratt JR, Kane KA, Bullock G Effects of prolonged administration of
oxprenolol on severity of ischaemic arrhythmias, enzyme leakage, infarct size and
intracellular cardiac muscle action potentials J Cardiovasc Pharmac (1984), 6, 369-377
Coker SJ, Parratt JR The effects of timolol on arrhythmias and prostanoid release during
canine myocardial ischaemia and reperfusion Br J Pharmac (1984), 81, 675-684
Furman BL, McKechnie K, Parratt JR Failure of drugs which selectively inhibit
thromboxane synthesis to modify endotoxin shock in conscious rats Br J Pharmac (1984),
82, 289-294
Hughes B, Kane KA, McDonald FM, Parratt JR Aspects of the cardiovascular pharmacology
of exaprolol J Pharm Pharmacol (1984), 36, 597-601
Fagbemi O, Parratt JR Antiarrhythmic actions of adenosine in the early stages of
experimental myocardial ischaemia Eur J Pharmacol (1984), 100, 243-244
Kane KA, Parratt JR, Williams FM An investigation into the characteristics of reperfusioninduced arrhythmias in the anaesthetised rat and their susceptibility to drugs Br J Pharmac
(1984), 82, 349-357
Coker SJ, Parratt JR Relationships between the severity of myocardial ischaemia, reperfusion
induced ventricular fibrillation and the late administration of dazmegrel or nifedipine J
Cardiovasc Pharmacol (1985), 7, 327-334
Coker SJ, Parratt JR Arachidonic acid cascade and the generation of ischaemia and
reperfusion-induced ventricular arrhythmias, J Cardiovasc Pharmacol (1985), 7, 565-570
McKechnie K, Dean HG, Furman BL, Parratt JR Plasma catecholamines during endotoxin
infusion in conscious unrestrained rats: effects of adrenal demedullation and/or guanethidine
treatment Circulatory Shock (1985), 17, 85-94
Kane KA, Morcillo-Sanchez EJ, Parratt JR, Rodger IW, Shahid M The relationship between
coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the
anaesthetised rat Br J Pharmacol (1985), 84, 139-145
Wainwright CL, Parratt JR The effect of beta-adrenoceptor blockade and of thromboxane
synthetase inhibition, alone and in combination, on arrhythmias resulting from myocardial
ischaemia Advances in Myocardiology (1985), 6, 573-584
Bullock GR, Lepran L, Parratt JR, Szekeres L, Wainwright CL The effects of metroprolol
and dazmegrel, alone and in combination, on arrhythmias induced by coronary artery
occlusion in conscious rats Br J Pharmacol (1985), 86, 229-234
Bullock GR, Lepran I, Parratt JR, Szekeres L, Wainwright CL Effects of a combination of
metoprolol and dazmegrel on myocardial infarct size in rats Br J Pharmacol (1985), 86, 235240
Hughes B, Parratt JR The effects of the protease inhibitor, aprotinin, on shock induced by
endotoxin in cats Br J Pharmacol (1985), 86, 399-403
Coker SJ, Parratt JR AH23848, a thromboxane antagonist, suppresses ischaemia and
reperfusion - induced arrhythmias in anaesthetised greyhounds Br J Pharmacol (1985), 86,
259-264
McKechnie K, Furman BL, Parratt JR Metabolic and cardiovascular effects of endotoxin
infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C
Circulatory Shock, (1985), 15, 205-215
Evis MJ, Kane KA, Moore MJ, Parratt JR The effects of chronic low level lead treatment and
hypertension both alone, and in combination, on the severity of cardiac arrhythmias induced
by coronary artery ligation in anaesthetised rats Toxicology & Applied Pharmacology
(1985), 80, 235-242
Williams FM, Rothaul AL, Kane KA, Parratt JR Antiarrhythmic and electrophysiological
effects of ICS 205-930, an antagonist of 5-hydroxytryptamine at peripheral receptors J
Cardiovasc Pharmacol (1985), 7, 550-555
Parratt JR, Sitsapesan R Stereospecific antiarrhythmic effect of opioid receptor antagonists in
myocardial ischaemia Br J Pharmac (1986), 87, 621-622
Williams FM, Coker SJ, Dean HG, Kane KA, Parratt JR Do alterations in prostanoid or
catecholamine release influence the antiarrhythmic activity of nicergoline? J Cardiovasc
Pharmac (1986) 8, 286-293
Evis MJ, Kane KA, Moore MR, Parratt J R The effects of ethanol and lead, alone and in
combination, on the severity of arrhythmias induced by coronary artery occlusion, and by
noradrenaline, in anaesthetised rats Arch Toxicol (1986) 59, 56-60
McKenzie JE, Marshall RJ, Parratt JR The haemodynamic and metabolic effects of
tolmesoxide with special reference to impaired myocardial function Br J Pharmac (1986) 89,
313-319
Parratt JR, Saleh S, Waton NG Feline endotoxin shock: effects on tissue histamine and
histidine decarboxylase activity Br J Pharmac (1986) 89, 635-640
Coker SJ, Dean HG, Kane KA, Parratt JR The effects of ICS 205-930, a 5-HT antagonist, on
arrhythmias and catecholamine release during canine myocardial ischaemia and reperfusion
Eur J Pharmacol (1986), 127, 211-218
McKechnie K, Furman BL, Parratt JR Modification by oxygen free radical scavangers of the
metabolic and cardiovascular effects of endotoxin infusion in conscious rats Circulat Shock
(1986), 19, 429-439
Pacitti N, Bryson SE, McKechnie K, Rodger IW, Parratt JR Leukotriene antagonist FPL
57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats Circulatory
Shock (1987) 21, 115-168
Evis M, Dhaliwal K, Kane KA, Moore MR, Parratt JR The effects of chronic lead treatment
and hypertension on the severity of cardiac arrhythmias induced by coronary artery occlusion
or by noradrenaline in anaesthetised rats Arch Toxicol (1987) 59, 336-340
Parratt JR, Wainwright CL Failure of allopurinol and a spin trapping agent N-t-butyl-phenyl
nitrone to modify significantly ischaemia and reperfusion-induced arrhythmias Br J
Pharmac (1987) 91, 49-59
Wainwright CL, Parratt JR Antiarrhythmic effects of the thromboxane antagonist BM 13177
Eur J Pharmac (1987) 133, 257-264
Williams FM, Rochette L, Kane KA, Parratt JR Effects of alterations in sympathetic nervous
activity on the severity of reperfusion-induced arrhythmias in anaesthetised rats J Cardiovasc
Pharmacol (1987) 10, 555-561
Wainwright CL, Parratt JR An antiarrhythmic effect of adenosine during myocardial
ischaemia and reperfusion Eur J Pharmac (1988) 145, 183-194
Wainwright CL, Parratt JR Alifedrine, a positive inotropic agent that moderately reduces the
severity of ischaemia and reperfusion-induced ventricular arrhythmias Eur J Pharmac
(1988) 147, 373-380
Wainwright CL, Parratt JR The effects of L655,240, a selective thromboxane and
prostaglandin endoperoxide antagonist, on ischaemia and reperfusion-induced cardiac
arrhythmias J Cardiovasc Pharmacol (1988), 12, 264-271
Parratt JR, Wainwright CL, Fagbemi O Effect of dopexamine hydrochloride in the early
stages of experimental myocardial infarction Amer J Cardiol (1988), 62, pp 18-23
Walker MJA, Curtis MJ, Hearse DJ, Parratt JR et al The Lambeth Conventions: guidelines
for the study of arrhythmias in ischaemia, infarction and reperfusion Cardiovascular Res
(1988), 22, 447-459
Wainwright CL, Parratt JR, Coker SJ, Zeitlin IJ
Biomed Biochim Acta (1988) 47, S13-S18
Eicosanoids and cardiac arrhythmias
Wainwright CL, Parratt JR, Bigaud M The effects of PAF antagonists on ischaemia and
reperfusion arrhythmias and ischaemia-induced platelet aggregation Biomed Biochim Acta
(1988) 47, S224-S227
Zeitlin IJ, Fagbemi O, Parratt JR Enzymes in normally perfused and ischaemic dog hearts
which release a substrate with kinin like activity Cardiovasc Res (1989) 23, 91-97
Zeitlin IJ, Fagbemi O, Parratt JR Coronary vessels contain enzymes that liberate kinin-like
vasodilator substances Eur Heart J (1989) 10, (Supplement F), 73-77
Boachie-Ansah G, Kane KA, Parratt JR Cardiac electrophysiological effects of isoprenaline,
phenylephrine and noradrenaline in normal and mildly "ischaemic" sheep Purkinje fibres J
Cardiovasc Pharmac (1989) 13, 291-298
Sitsapesan R, Parratt JR The effects of drugs interacting with opioid receptors on the early
ventricular arrhythmias arising from myocardial ischaemia Br J Pharmac (1989) 97, 795-800
Boachie-Ansah G, Sitsapesan R, Kane KA, Parratt J R The antiarrhythmic and cardiac
electrophysiological effects of buprenorphine Br J Pharmac (1989) 97, 801-808
Boachie-Ansah G, Kane KA, Parratt JR Electrophysiological effects of adenosine and
adenosine triphosphate on mildly 'ischaemic' sheep Purkinje fibres Br J Pharmacol (1989)
97, 240-246
Wainwright CL, Parratt JR, Bigaud M The effects of PAF antagonists on arrhythmias and
platelets during acute myocardial ischaemia and reperfusion Eur Heart J (1989), 10, 235-243
Williams PE, Leaver HA, Smith G, Parratt JR, Pacitti N, Ramsay G, Ledingham IM, Yap PL
The endotoxin receptor on mononuclear phagocytes FEMS Microbiol Immunol (1990) 64,
11-12
Bigaud M, Julou-Schaeffer G, Parratt JR, Stoclet J-C Endotoxin-induced impairment of
vascular smooth muscle contractions elicited by different mechanisms Eur J Pharmacol
(1990) 190, 185-192
Guc MO, Furman BL, Parratt JR Endotoxin induced impairment of vasopressor and
vasodepressor responses in the pithed rat Br J Pharmacol (1990) 101, 913-919
Gray GA, Julou-Schaeffer G, Oury K, Fleming I, Parratt JR, Stoclet J-C An L-argininederived factor mediates endotoxin-induced vascular hyposensitivity to calcium Eur J
Pharmacol (1990) 191, 89-92
Fleming I, Gray GA, Julou-Schaeffer G, Parratt JR, Stoclet J-C Incubation with endotoxin
activates the L-arginine pathway in vascular tissue Biochem & Biophysic Res Comms
(1990) 171, 562-568
Julou-Schaeffer G, Gray GA, Fleming I, Schott C, Parratt JR, Stoclet J-C Loss of vascular
responsiveness induced by endotoxin involves the L-arginine pathway Am J Physiol (1990)
259 (Heart Circ Physiol, 28): H1038-H1043
Vegh A, Szekeres L, Parratt JR Protective effects of preconditioning of the ischaemic
myocardium involve cyclo-oxygenase products Cardiovasc Res (1990) 24, 1020-1022
Gray GA, Furman BL, Parratt JR Endotoxin-induced impairment of vascular reactivity in the
pithed rat: Role of arachidonic acid metabolites Circ Shock (1990) 31, 395-406
Parratt JR, Komori S and others Ischemic preconditioning Jpn J Electrocardiology (1990)
10, 774-782
Wainwright CL, Parratt JR Failure of cyclo-oxygenase inhibition to protect against
arrhythmias induced by ischaemia and reperfusion: implications for the role of prostaglandins
as endogenous myocardial protective substances Cardiovasc Res (1991) 25, 93-101
Fleming I, Julou-Schaeffer G, Gray GA, Parratt JR, Stoclet J-C Evidence that an Larginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in
depression of vascular reactivity by endotoxin Br J Pharmacol (1991) 103, 1047-1052
Julou-Schaeffer G, Gray GA, Fleming I, Schott C, Parratt JR, Stoclet J-C Activation of the
L-arginine-nitric oxide pathway is involved in vascular hyporeactivity induced by endotoxin
J Cardiovasc Pharmacol (1991) 17, S207-S212
Gray GA, Schott C, Julou-Schaeffer G, Fleming I, Parratt JR, Stoclet J-C The effect of
inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular
responsiveness in anaesthetised rats Br J Pharmacol (1991) 103, 1218-1224
Vegh A, Szekeres L, Parratt, JR Local intracoronary infusions of bradykinin profoundly
reduce the severity of ischaemia-induced arrhythmias in anaesthetised dogs Br J Pharmacol
(1991) 104, 294-295
Vegh A, Szekeres L, Parratt JR Transient ischaemia induced by rapid cardiac pacing results
in myocardial preconditioning Cardiovasc Res (1991) 25, 1051-1053
Guc MO, Furman BL, Parratt JR Endotoxin impairs the response of rat anococcygeus muscle
to electrical field stimulation Eur J Pharmacol (1991) 202, 397-401
Guc MO, Gray GA, Furman BL, Parratt JR Endotoxin-induced impairment of vasodepressor
responses in the pithed rat Eur J Pharmacol (1991) 204, 63-70
Parratt JR, Stoclet J-C Possible role of nitric oxide in refractory hypotension associated with
sepsis and endotoxaemia with multiple organ failure App Cardiopulmonary Pathophysiol
(1991) 4, 143-149
McIntosh M, Kane K, Parratt JR Effects of selective opioid receptor agonists and antagonists
during myocardial ischaemia Eur J Pharmacol (1992) 210, 37-44
McIntosh M, Kane K, Parratt JR The electrophysiological effects of opioid receptor-selective
antagonists on sheep Purkinje fibres Eur J Pharmacol (1992) 210, 45-51
Vegh A, Komori S, Szekeres L, Parratt JR Antiarrhythmic effects of preconditioning in
anaesthetised dogs and rats. Cardiovasc Res (1992) 26, 487-495.
Moshi MJ, Zeitlin IJ, Wainwright CL. Parratt JR. Acid optimum kininogenases in canine
myocardium and aorta. Cardiovasc Res (1992) 26, 367-370.
Vegh A, Szekeres L, Parratt JR. Preconditioning of the ischaemic myocardium; involvement
of the L-arginine nitric oxide pathway. Br J Pharmacol (1992) 107, 648-652.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. The local intracoronary administration of
methylene blue prevents the pronounced antiarrhythmic effects of ischaemic preconditioning.
Br J Pharmacol (1992) 107, 901-911.
Vegh A, Szekeres L, Parratt JR, Papp J Gy. The role of nitric oxide in myocardial
preconditioning. Pharmacol Res. Communications (1992) 25, Suppl 2, 181-182.
Guc MO, Furman BL, Parratt JR. Modification of a-adrenoceptor-mediated pressor responses
by NG-L-arginine methyle ester and vasopressin in endotoxin-treated pithed rats. Eur J
Pharmacol (1992) 224, 63-69.
Komori S, Osada M, Sano S, Ishihara T, Sato H, Sawanobori T, Ijiri H, Watanabe Y, Tamura
K, Parratt JR. Ischemic preconditioning reduces the severity of ventricular arrhythmias
induced by coronary artery occlusion in rats. Yamanashi Med J (1992) 7(2), 43-52.
Boachie-Ansah G, Kane KA, Parratt JR. Is adenosine an endogenous myocardial protective
(antiarrhythmic) substance under conditions of ischaemia. Cardiovasc Res (1993) 27, 77-83.
Wainwright CL, Parratt JR, van Belle, H. The antiarrhythmic effects of the nucleoside
transport inhibitor R75231 in anaesthetised pigs. Br J Pharmacol (1993).109, 592-599
Stoclet J-C, Fleming I, Gray GA, Julou-Schaeffer G, Schneider F, Schott C, Schott C, Parratt
JR. Nitric oxide and endotoxaemia. Circulation (1993) 87, V77-V80.
Piacentini L, Wainwright CL, Parratt JR. The antiarrhythmic effect of ischaemic
preconditioning in isolated rat heart involves a pertussis toxin sensitive mechanism.
Cardiovasc Res (1993) 27, 674-680.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. Are ATP sensitive potassium channels involved
in the pronounced antiarrhythmic effects of preconditioning? Cardiovasc Res (1993) 27, 638643.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. Prevention by an inhibitor of the L-arginine nitric
oxide pathway of the anitarrhythmic effects of bradykinin in anaesthetised dogs. Br J
Pharmacol (1993) 110, 18-19.
Laycock SK, McMurray J, Kane KA, Parratt JR. Effects of xanthine oxidase system on
cardiac function in anaesthetised rats. Free Radical Biology and Medicine (1993) 15, 249255.
Wainwright CL, Parratt JR. The effects of R-PIA, a selective A1-adenosine agonist on
haemodynamics and ischaemia-induced arrhythmias in pigs. Cardiovasc Res 1993, 27, 8489.
Bouvier C, Guc OM, Furman BL, Parratt JR. Platelet activating factor inpairs pressor
responses to noradrenaline in the anaesthetised rat but does not mediate endotoxin-induced
hyporeactivity. Circ Shock 1994, 42, 114-19.
Komori S, Sawanobori T, Tamura K, Kane KA, Parratt JR. Effects of NS-2, a new class I
antiarrhythmic agent, and AFD-19, its active metabolite, on ventricular arrhythmias induced
by coronary artery occlusion and reperfusion in anesthetised rats: Comparison with
disopyramide and mexiletine. Jpn J Pharmacol 1994, 65, 193-200.
Parratt JR, Vegh A. Pronounced antiarrhythmic effects of ischemic preconditioning.
Cardioscience 1994,5:9-18.
Vegh A, Papp J Gy, Parratt JR. Prevention by dexamethasone of the marked antiarrhythmic
effects of preconditioning induced 20 h after rapid cardiac pacing. Br J Pharmacol 1994,
113:1081-1082.
Vegh A, Papp J Gy, Parratt JR. Attenuation of the antiarrhythmic effects of ischaemic
preconditioning by blockade of bradykinin B2 receptors. Br J Pharmacol 1994, 113:11671172.
Wu Song, Furman BL, Parratt JR (1994) Attenuation by dexamethason of endotoxin
protection against ischaemia-induced ventricular arrhythmias. Br J Pharmacol 1994,
113:1083-1084.
Fatehi-Hassanabad Z, Furman BL, Parratt JR (1995) The effect of endotoxin on sympathetic
responses in the rat isolated perfused mesenteric bed; involvement of nitric oxide and cyclooxygenase products. Br J Pharmacol 116,3316-3322.
Laycock SK, McMurray J, Kane KA, Parratt J R (1995) Effects of chronic norepinephrine
administration on cardiac function in rats. J Cardiovasc Pharmacol 26, 584-589.
McIntosh M, Kane KA, Parratt JR. The effects of opioid peptides on cardiovascular function
and sympathetic neurotransmission in rats. J Pharm Pharmacol 1995, 47:52-58.
Parratt J, Vegh A, Papp J Gy (1995) Pronounced antiarrhythmic effects of ischaemia
preconditioning - are there possibilities for pharmacological exploitation? Pharmacol Res 31,
225-234.
Ravingerova T, Pyne NJ, Parratt JR (1995) Ischaemic preconditioning in the rat heart: The
role of G-proteins and adrenergic stimulation. Molec Cell Biochem 147, 123-128.
Vegh A, Papp J Gy, Parratt JR (1995) Pronounced antiarrhythmic effects of preconditioning
in anaesthetised dogs: is adenosine involved. J Mol Cell Cardiol 27, 349-356.
Parratt JR (1995)
Possibilities for the pharmacological exploitation of ischaemic
preconditioning. J Mol Cell Cardiol 27, 991-1000.
Parratt JR, Vegh A, Papp J Gy (1995) Bradykinin as an endogenous myocardial protective
substance with particular reference to ischemic preconditioning - a brief review of the
evidence. Canad J Physiol Pharmacol 73, 837-884.
Moshi MJ, Zeitlin IJ, Parratt JR (1995)
myocardium. J Cardiovasc Risk 2, 331-337.
An acidic kininogenase in rat ventricular
AHMAD M, ZEITLIN IJ and PARRATT JR (1996) The release of kininase from rat isolated
hearts during myocardial ischaemia. Immunopharmacology 33, 299-300.
AHMAD M, ZEITLIN IJ, PARRATT JR and KOLAR K (1996) Kinin release from normally
perfused and ischaemic isolated rat hearts: effect of strain. Immunopharmacology 33,
FATEHI-HASSANABAD Z, BURNS H, AUGHEY E A, PAUL A, PLEVIN R , PARRATT
J R and FURMAN B L (1996). Effects of L-canavanine, an inhibitor of inducible nitric oxide
synthase, on endotoxin-mediated shock in the rat. Shock 6: 194-200.
FATEHI-HASSANABAD Z, MULLER B, ANDRIANTSITOHAINA R, FURMAN BL,
PARRATT JR and STOCLET JC (1996). Influence of indomethacin on the haemodynamic
effects of lipopolysaccharide. Fundam Clin Pharmacol 10, 258-263.
FATEHI-HASSANABAD Z, PARRATT JR and FURMAN BL (1996) Endotoxin-induced
inhibition of mesenteric vasodilator responses to acetylcholine, bradykinin, and postocclusion hyperemia in anesthetised rats. Shock 6, 371-376.
FORSTER W and PARRATT JR (1996) The case for low-dose aspirin for the prevention of
myocardial infarction: But how low is low? Cardiovasc Drugs & Ther 10, 727-734.
KASZAKI J, WOLFARD A, BARI F, BOROS M, PARRATT JR and NAGY S (1996)
Effect of nitric oxide synthase inhibition on myocardial contractility in anesthetized normal
and endotoxemic dogs. Shock 6, 279-285.
KASZALA K, VEGH A, PAPP J GY and PARRATT JR (1996) Time course of the
protection against ischaemia and reperfusion-induced ventricular arrhythmias resulting from
brief periods of cardiac pacing. J Mol Cell Cardiol 28, 2085-2095.
LAYCOCK SK, KANE KA, McMURRAY J, and PARRATT JR (1996) Captopril and
norepinephrine-induced hypertrophy and haemodynamics in rats. J Cardiovasc Pharmacol
27, 667-672.
PARRATT JR and VEGH A (1996) Endothelial cells, nitric oxide and ischaemic
preconditioning. Basic Res Cardiol 91, 27-30.
PARRATT JR, VEGH A, KASZALA K and PAPP J GY (1996) Protection by
preconditioning and cardiac pacing against ventricular arrhythmias resulting from ischemia
and reperfusion. Annal of the New York Acad of Sciences 793, 98-107.
SONG W, FURMAN BL and PARRATT JR (1996). Delayed protection against ischaemiainduced ventricular arrhythmias and infarct size limitation by the prior administration of
Escherichia coli endotoxin. Br J Pharmacol 118, 2157-2163.
VEGH A, GYORGYI K, PAPP J GY, SAKAI K and PARRATT JR (1996) Nicorandil
suppressed ventricular arrhythmias in a canine model of myocardial ischaemia. Eur J
Pharmacol 305, 163-168.
WILSON S, SONG W, KAROLY K, RAVINGEROVA T, VEGH A, PAPP J, TOMISAWA
S, PARRATT JR and PYNE NJ (1996) Delayed cardioprotection is associated with the subcellular relocalisation of ventricular protein kinase C, but not p42/44 MAPK. Molec Cell
Biochem 160/161, 225-230.
KASZALA K, VEGH A, PAPP J GY and PARRATT JR (1997) Modification by bradykinin
B2 receptor blockade of protection by pacing against ischaemia-induced arrhtyhmias. Eur J
Pharmacol 328, 51-60.
FATEHI-HASSANABAD Z and PARRATT JR (1997) Genistein, an inhibitor of tyrosine
kinase, prevents the antiarrhythmic effects of preconditioning. Eur J Pharmacol 338, 67-70.
FORSTER W and PARRATT JR (1997) The case for low-dose aspirin for the prevention of
myocardial infarction: but how low is low? Cardiovasc Drugs Ther, 10, 727-734.
PARRATT, JR and VEGH, A (1997) Delayed protection against ventricular arrhythmias by
cardiac pacing. Heart 78, 423-425.
PARRATT JR, VEGH A, ZEITLIN IJ, AHMAD M, OLDROYD K, KASZALA K, and
PAPP J Gy (1997) Bradykinin and endothelial-cardiac myocyte interactions in ischemic
preconditioning. Am J Cardiol 80, 124A-131A.
RAVINGEROVA T, SONG W, PANCZA D, DZURBA A, ZIEGELHOEFFER A, and
PARRATT JR (1997) Pretreatment with catecholamines can suppress severe ventricular
arrhythmias in rats: Relevance to ischemic preconditioning. Exp Clin Cardiol 2, 19-24.
VEGH A, PAPP J Gy, GYORGY K, KASZALA K and PARRATT JR (1997) Does the
opening of ATP-sensitive K+ channels modify ischaemia-induced ventricular arrhythmias in
anaesthetised dogs? Eur J Pharmacol 333, 33-38.
KOLAR F, PARRATT JR (1997) Antiarrhythmic effect of ischemic preconditioning in
hearts of spontaneously hypertensive rats. Experimental Cardiology 2, 124-127.
WILSON S, LUGNIER C, STOCLET J-C, VEGH A, PYNE N and PARRATT JR (1997)
Phosphoidesterase isozymes from the hearts of dogs subjected to cardiac pacing.
Experimental Cardiology 2, 103-106.
KIS A, VEGH A, PAPP J GY and PARRATT JR (1997) Simultaneous blockade of the
cyclooxygnease and L-arginine nitric oxide pathways prevents the antiarrhythmic effects of
classical preconditioning. Experimental Cardiology 2, 112-118.
Parratt JR Nitric oxide. A key mediator in sepsis and endotoxaemia? J Phyiol Pharmacol
48, 493-509.
Parratt JR Nitric oxide in sepsis and endotoxaemia. J Antimicrobial Chemotherapy (1998)
41, 31-39.
Humphreys RA, Kane KA and Parratt JR (1998) Lack of involvement of mast cell
degranulation in the antiarrhythmic effect of preconditioning in rats. J Cardiovasc Pharm 31,
418-423.
Valen G, Takeshima S, Ahmad M, Zeitlin I, Parratt JR, Vaage J (1997) Bradykinin in open
heart surgery: Metabolism of bradykinin in the coronary circulation during reperfusion. Clin
Cardiol 2, 223-227.
Végh Á., Papp J.Gy., Semeraro C., Fatehi-Hasanabad Z., Parratt J.R. The dopamine receptor
agonist Z1046 reduces ischaemia severity in a canine model of coronary artery occlusion.
Eur. J. Pharmacol. 344: 203-213, 1998.
Kis A., Végh Á., Papp J.Gy., Parratt J.R. Repeated cardiac pacing extends the time during
which canine hearts are protected against ischaemia-induced arrhythmias: role of nitric oxide.
J. Mol. Cell. Cardiol. 31: 1229-1241, 1999.
Kis A., Végh Á., Papp J.Gy., Parratt J.R. Pacing induced delayed protection against
arrhythmias is attenuated by aminoguanidine, an inhibitor of nitric oxide synthase. Brit. J.
Pharmacol. 127: 1545-155, 1999.
Parratt J.R.: Végh Á. Coronary vascular endothelium – myocyte interactions in protection of
the heart by ischaemic preconditioning. J. Physiol. Pharmacol. 50: 509-524, 1999.
Végh Á., György K., Rastegar M. A., Papp J.Gy., Parratt J.R. Delayed protection against
ventricular arrhythmias by monophosphoryl lipid-A in a canine model of ischaemia and
reperfusion. Eur. J. Pharmacol. 382(2): 81-90, 1999.
György K., Végh Á., Rastegar M.A., Papp J.Gy., Parratt J.R. Isosorbide-2-mononitrate
reduces the consequences of myocardial ischaemia,
including arrhythmia severity:
implications of preconditioning. Cardivasc. Drugs Ther. 14: 481-488, 2000.
Kis A., Végh Á., Papp J.Gy., Parratt J.R. Cardiac pacing-induced delayed protection against
ventricular arrhyhmias: Evidence for the role of nitric oxide. Exp. Clin. Cardiol. 5: 17-23,
2000.
Rastegar M.A., Marchini F., Morazzoni G., Végh Á., Papp J.Gy., Parratt J.R. The effects of
Z13752A, a combined ACE/NEP inhibitor, on responses to coronary artery occlusion; a
primary protective role for bradykinin. Brit. J. Pharmacol. 129: 671-680, 2000.
Rastegar M.A., Végh Á., Papp J.Gy., Parratt J.R. Atrial natriuretic peptide reduces the severe
consequences of coronary artery occlusion in anaesthetised dogs. Cardiovasc. Drugs Ther. 14:
471-478, 2000.
Babai L., Papp J.Gy., Parratt J.R., Végh Á. The antiarrhythmic effects of ischaemic
preconditioning in anaesthetized dogs are prevented by atropine; role of changes in
baroreceptor reflex sensitivity. Br. J. Pharmacol. 135: 55-64, 2002.
Babai L., Szigeti Zs., Parratt J.R., Végh Á. Delayed cardioprotective effects of exercise in
dogs are aminoguanidine sensitive: possible involvement of nitric oxide. Clin. Science 102:
435-445, 2002.
Végh Á., Parratt J.R. Noradrenaline, infused locally, reduces arrhythmia severity during
coronary artery occlusion in anaesthetised dogs. Cardiovasc. Res. 55: 53-63, 2002.
Végh Á., Parratt J.R. The role of mitochondrial KATP channels in the antiarrhythmic effects of
ischaemic preconditioning in dogs. Br. J. Pharmacol. 137: 1107-1115, 2002.
Szigeti Zs., Simon K., Parratt J.R., Végh Á. Effects of delayed preconditioning on myocardial
regional contractility during repeated episodes of low-flow ischaemia in anaesthetized dogs:
possible role of nitric oxide. Clin. Science 106: 201-213, 2004.
Nagy O., Hajnal Á., Parratt J.R.,Végh Á. Sildenafil (Viagra) reduces arrhythmia severity
during ischaemia 24h after oral administration in dogs. Br. J. Pharmacol. 141: 549-551, 2004.
REVIEWS
Parratt JR Pharmacologically active substances in plants J Pharm Soc Nig (1961), 1, 49-53
Parratt JR Pharmacological aspects of the coronary circulation
Chemistry, Ed GP Ellis and GB West, (1969), 6, 11-66
Progress in Medical
Parratt JR Some aspects of the pharmacology of anti-anginal drugs Acta Cardiologia (1969)
Suppl 13, 191-209
Parratt JR Effets cliniques et circulatoires des vaso-dilatateurs: le concept de 'vol coronarien'
La Revue de Medecine (1975), 16, 25-34
Parratt JR Recent advances in the pathophysiology and pharmacology of angina Comp Gen
Pharmac (1975), 6, 247-251
Parratt JR The search for prophylactic antidysrhythmic drugs - the place of aminosteroids
Progress in Pharmacology (1979) 2, 85-94
Parratt JR Nitroglycerin - the first hundred years: new facts about an old drug J Pharmac &
Pharmacol (1979) 31, 801-809
Parratt JR Editorial: Nitroglycerin - the first one hundred years Lancet (1979) ii, 1340-1341
Parratt JR Advances in the pathophysiology and drug treatment of angina pectoris
Pharmaceutical Journal (1980) 224, 263-265
Parratt JR In praise of nitroglycerin - a celebrated centenary Trends in Pharmacological
Sciences (1980) 428-430
Parratt JR Marshall RJ Pharmacological attempts to improve blood flow and the balance
between oxygen supply and demand in the early stages of experimental myocardial infarction
Progr Pharmacol (1981) 4, 55-63
*Parratt JR The evidence for a-adrenoceptors in the coronary circulation and their possible
relevance to the physiological regulation of myocardial blood flow Basic Res Cardiology
(1981) 76, 485-493
Parratt JR, Coker SJ, Ledingham IMcA Prostaglandins, thromboxanes and the early events of
myocardial ischaemia Health Bull (1983) 41, 42-50
Parratt JR, Coker SJ, William F, Kane KA The pharmacology of reperfusion arrhythmias
Clin Res Rev (1984), 4, (1), 50-54
Parratt JR Arrhythmias and the ischaemic myocardium Cardiovascular Focus (1983) 9, 1-5
Parratt JR Beta-adrenoceptor blocking drugs in experimental models relating to angina
pectoris Progress in Pharmacology (1985), 4, 25-34
Parratt JR The pharmacological protection of the ischaemic myocardium Problems and
possibilities Proc 4th Cong Hung Pharmacol Soc Budapest (1985), Vol 1, 89-98
Parratt JR Opioid receptors in the cardiovascular system Progress in Pharmacology (1986)
Vol 6, Gustav Fischer Verlag, 97-110
Parratt JR Critical appraisal of secondary prevention after myocardial infarction What have
beta-blockers to offer in the experimental situation? Eur Heart J (1986) 7, (Supp B) 19-25
Parratt JR Pathophysiology of myocardial ischemia: importance of platelet-vessel wall
interactions Cardiovascular drugs and Therapy (1988) 2, 35-40
Parratt JR
The pharmacology of positive inotropic agents in acute heart failure
Cardiopulmonary Pathophysiology (1989) 3, 85-93
Parratt JR. Vascular reactivity in sepsis and endotoxaemia - a pivotal role for endotoxin.
Intensivmedizin (1992) 81, 94-103.
Parratt JR. Endogenous myocardial protective (antiarrhythmic) substances. Cardiovasc Res
(1993) 27, 693-702.
Parratt JR, Kane KA. KATP channels in ischaemic preconditioning. Cardiovasc Res 1994,
28, 783-787.
Parratt JR. Cardioprotection by angiotensin converting enzyme inhibitors - the experimental
evidence. Cardiovasc Res (1994) 28, 183-189.
Parratt JR. Protection of the heart by ischaemic preconditioning: mechanisms and
possibilities for pharmacological exploitation. TIPS (1994) 5, 19-25.
Ravingerova T, Pyne NJ, Parratt JR. Adrenergic stimulation protects rat hearts against severe
arrhythmias: relevance to ischaemic preconditioning. Proceedings International Society for
Heart Research, Copenhagen (1994) Eds S Haunso & K Kjeldsen.
Parratt JR, Vegh A. Pronounced antiarrhythmic effects of ischaemic preconditioning.
Cardioscience (1994) 5, 9-18..
Parratt JR, Szekeres L (1995) Delayed protection of the heart against ischaemia. TIPS 6,
351-355.
BOOKS
Parratt JR (ed) Early arrhythmias resulting from myocardial ischaemia: mechanisms and
prevention by drugs London:Macmillan and New York:Oxford University Press (1982) 381
pages
Parratt JR (ed) Control and Manipulation of Calcium Movement Raven Press, New York
(1985), 394 pages
Parratt JR (ed) Myocardial Response to Acute Injury London:Macmillan (1992) 251 pages
Wainwright CL and Parratt JR , Myocardial Preconditionining (eds) Springer, Berlin (1996)
BOOK CHAPTERS
Parratt JR The effect of catecholamines on myocardial metabolic heat production In:- Drugs
and metabolism of myocardium and striated muscle Ed M Lamarche & R Roger, University
of Nancy (1969) p217-222
Parratt JR Changes in myocardial metabolic heat production induced by anti-anginal drugs
In:- Drugs and metabolism of myocardium and striated muscle Ed M Lamarche & R Roger,
University of Nancy (1969) p265-272
Moore G, Parratt JR Effects of oxyfedrine on local myocardial blood flow, myocardial
metabolic heat production, contractility and wall tension In: Action of oxyfedrine Ed E
Gerlach & K Moser Schattauer-Verlag, Stuttgart (1972) p181-191
Ledingham IMcA, Parratt JR, Vance JP Myocardial blood flow and metabolism in shock In:
Conference on shock Ed I McA Ledingham & TA McAllister, Henry Kimpton, London
(1972) p13-19
Parratt JR Effect of anti-anginal drugs on the coronary circulation and the metabolic heat
production of the heart In Symposium on drugs and heart metabolism First Congress of the
Hungarian Pharmacological Society, Budapest, l97l Edited by J Knoll, L Szekeres and J Gy
Papp, Budapest, Akademiai Kiado, (1973) 2, 79-87
Parratt JR Pharmacological approaches to the therapy of angina In: Advances in Drug
Research Edited by NJ Harper and AB Simmonds, New York, Academic press, (1974) 9,
103-134
Ledingham IMcA, Parratt JR Pathophysiology of shock In: Shock Clinical and experimental
aspects, Ed I McA Ledingham, p1-20 Excerpta Med Amsterdam (1976)
Parratt JR Recent aspects of the determinants of blood flow in the acutely ischaemic
myocardium In: New aspects in the therapy of ischaemic disease Ed AL Myasnikov p16-30
Homburg Degussa: Frankfurt (1977) (in Russian)
Parratt JR, Marshall RJ Drug-induced changes in blood flow and oxygen consumption in the
acutely ischaemic myocardium In: Der Herzinfarkt Ed G Schettler, A Horsch, H Morl, H
Orth & A Weizel p282-301 Schattauer: Stuttgart (1977)
Parratt JR Effects of adrenergic activators and inhibitors on the coronary circulation In:
Handbook of Experimental Pharmacology, 54, (1) 735-822 (1980)
Parratt JR Arrhythmias in the ischaemic heart In: Cardiac arrhythmias and the slow Ca++
current Ed RG Richardson p47-57 Abbott: Queensborough (1980)
Parratt JR Beta-adrenoceptor blockade and early post-infarction dysrhythmias In: The
clinical impact of beta-adrenoceptor blockade ed Burley, DM and Birdwood, GFB (1980)
p29-50 Horsham: Ciba Laboratories
Parratt JR, Coker SJ The significance of prostaglandin and thromboxane release in acute
myocardial ischaemia In: Prostaglandins and Thromboxanes in the Cardiovascular System
and in Gynaecology and Obstetrics Ed W Forster p21-25 Fischer: Jena (1981)
Parratt JR Alpha-adrenoceptors in the coronary circulation: A review of the evidence In:
Les alpha-bloquants; pharmacologie experimentale et clinique, an international symposium
Masson: Paris (1981), pages 158-168
Campbell C, Fagbemi O, Parratt JR Catecholamines and early post-infarction arrhythmias:
the effects of alpha and beta-adrenoceptor blockade In: Catecholamines and the Heart Ed W
Delius, E Gerlach, H Grobecker & W Kubler (1981) p269-284 Berlin: Springer
Kane KA, McDonald FM, Parratt JR The anaesthetised rat as a model for investigating early
post-ligation dysrhythmias In: The rat electrocardiogram in pharmacology and toxicology
ed R Buden, RK Detweiler and G Binden, (1981), p235-238 Oxford; Pergamon
Parratt JR Myocardial metabolic activity as a determinant of coronary vessel tone In: The
coronary artery, ed S Kalsner (1981) p309-339 London; Croom Helm
Parratt JR, Coker SJ, Macdonald A, Ledingham IMcA, Rodger IW, Zeitlin IJ The possible
role of prostaglandins and thromboxanes in the pulmonary consequences of experimental
endotoxin shock and clinical sepsis
In: The role of chemical mediators in the
pathophysiology of acute illness and injury Ed Rita McConn (1982), p195-218 New York:
Raven
Parratt JR Inhibitors of the slow calcium current and early ventricular arrhythmias In: Early
arrhythmias resulting from myocardial ischaemia: mechanisms and prevention by drugs ed
JR Parratt (1982) p329-346, MacMillan: London
Parratt JR Drug-induced changes in myocardial blood flow following acute coronary artery
ligation In: Microcirculation of the Heart: theoretical and clinical problems ed H Tillmanns,
W Kubler, H Zebe, (1982), p313-324, Heidelberg: Springer
Parratt JR Calcium slow channel blocking drugs and early ventricular arrhythmias resulting
from myocardial ischaemia and subsequent reperfusion In: Calcium Modulators ed T
Godfraind, A, Albertini, R Paoletti, (1982), p87-98, Elsevier: Amsterdam
Parratt JR The role of beta-adrenoceptors in the heart and circulation in health and disease
In: Biologie et pathologie du coeur et des vaisseaux ed J de Leiris, A Rossi, P Kircher, A
Roy, (1982), p39-52, University of Grenoble Press
Parratt JR Neurohumoral agents and their release in shock In: Handbook of Shock and
Trauma, Volume 1 (Basic Science), Ed BM Altura, AM Lefer & W Schumer (1983), pp311336, New York: Raven Press
Parratt JR The pharmacological modification of coronary blood flow in the acutely
ischaemic myocardium In: Myocardial ischaemia and protection ed H Refsum, P Jynge &
OD Mjos, (1983) pp 133-147, Edinburgh: Churchill Livingstone (with RJ Marshall)
Parratt JR Pulmonary function in experimental endotoxin shock - an examination of the role
of chemical mediators In: Shock Research, ed DH Lewis and U Haglund (1983) pp129-145,
Elsevier: Amsterdam
Parratt JR Myocardial and coronary vascular alpha-adrenoceptors with special reference to
acute myocardial ischaemia In: Symposium International Alpha-bloquants
Medicales
Specia, Paris, (1984) pp45-49
Parratt JR Aspirin in the early stages of myocardial infarction In: Royal Society of Medicine
International Congress and Symposium (1984), Series 71, 71-75
Parratt JR Coronary vascular endothelium, spasm and reperfusion arrhythmias; experimental
approaches In: Unstable Angina, ed PG Hugenholtz & BS Goldman, Schattauer, Stuttgart
(1985), 19-28
Parratt JR a-adrenoceptors in the coronary circulation: physiological importance and clinical
implications In: Alpha-adrenoceptor blockers in Cardiovascular Disease, ed H Refsum & OD
Mjos, L Churchill-Livingstone, Edinburgh (1985), 229-248
Parratt JR The role of arachidonic acid metabolites in endotoxin shock I Role of lipoxygenase
products In: Handbook of Endotoxin, Vol 2, ed LB Hinshaw, Elsevier, North Holland
(1985), 203-236
Parratt JR Blockade of calcium channels: effects on ventricular arrhythmias arising as a
result of myocardial ischaemia and reperfusion In: Control and Manipulation of Calcium
Movement, ed JR Parratt, Raven Press, New York (1985), 367-385
Parratt JR, Coker SJ Thromboxane, prostacyclin and the severity of early ischaemic and
reperfusion arrhythmias: a review of the evidence In: Prostaglandins and other Eicosanoids
in the Cardiovascular System, ed K Schror, Karger (1985), 172-182
Parratt JR Cardioprotective effects of iloprost Prostacyclin and its stable analogue iloprost
Eds RJ Gryglewski, G Stock, Berlin: Springer-Verlag, (1987) pp 301-304
Parratt JR Modification of the thromboxane/prostacyclin balance as an approach to
antiarrhythmic therapy during myocardial ischaemia and reperfusion; the concept of
endogenous antiarrhythmic substances In: Myocardial Ischaemia, ed NS Dhalla, IR Innes &
RE Beamish Martinus Nijhoff: Boston (1987), pp21-35
Parratt JR, Pacitti N The possible role of lipoxygenase products of arachidonic acid
metabolism and of platelet activating factor in shock In: Update in intensive care and
emergency medicine No 4 Septic Shock, European view ed JLVincent and LG Thijs
Springer, Heidelberg (1987) p74-88
Parratt JR, Wainwright CL, Coker SJ Eicosanoids and cardiac arrhythmias In: Pharmacology
Proceedings of the Xth International Congress of Pharmacology (IUPHAR) Sydney, 1987 ed
MJ Rand and C Raper Excerpta Medica, Amsterdam pp 501-506
Parratt JR Reperfusion arrhythmias, platelet-vessel wall interactions and endogenous
antiarrhythmic substances In: Cardiovascular Pharmacology '87, ed J Gy Papp, Akademiai
Kiado: Budapest, pp3-16
Parratt JR Calcium antagonists in tissue low-perfusion states ("shock")
antagonists, IBC Technical Services, London (1987) pp 127-135
In: Calcium
Parratt JR, Wainwright CL Reperfusion arrhythmias - an update In: Update in Intensive care
and emergency Medicine No 5 (1988) 293-302, ed JL Vincent
Parratt JR, Boachie-Ansah G, Kane KA, Wainwright CL Is adenosine an endogenous antiarrhythmic agent under conditions of myocardial ischaemia? In: Adenosine and adenine
nucleotides, physiology and pharmacology ed DM Paton London: Taylor and Francis
(1988) 157-166
Parratt JR, Fagbemi O, Kane KA Antiarrhythmic action and cardiac electrophysiological
effects of acute and chronic administration of prenylamine In: Prenylamine: A novel
approach to myocardial protection ed AS Manning & GL Szendey New York: Raven (1988)
pp43-56
Parratt JR Eicosanoids and arrhythmogenesis In: Handbook of Experimental Pharmacology,
Vol 89 'Antiarrhythmic Drugs' (1988), Ed E M Vaughan-Williams, pp 569-589, Springer
Verlag
Parratt JR Opioid peptides and the cardiovascular system with especial reference to low
perfusion states In: Heart & Brain (1988) Ed H Refsum, Springer Verlag, pp 20-36
Parratt JR Agents effective in the limitation of myocardial ischaemic damage: present
concepts and future possibilities In: Limitations of Infarct Size ed H M Schmutzler, W
Rutsch and F C Dougherty Springer-Berlin (1989) pp 235-245 (also edited discussion on
pages 39-41)
Parratt JR Alterations in vascular reactivity in sepsis and endotoxemia In: Update in
Intensive Care and Emergency Medicine, volume 8 ed J L Vincent Springer-Berlin pp 299308 (1989)
Parratt JR, Pacitti N, Rodger IW Mediators on acute lung injury in endotoxaemia In: Second
Vienna Shock Forum, Progress in Clinical and Biological Research Vol 308, Alan Liss Inc,
New York, 1989, pp357-369
Parratt JR Calcium antagonists in shock - a minireview of the evidence In: Second Shock
Forum, Progress in Clinical and Biological Research (1989) 308, 1065-1074 Alan Liss Inc,
New York
Wainwright CL, Parratt JR Effect of BN 52021 on platelet behaviour and arrhythmias during
myocardial ischaemia and reperfusion In: Ginkolides; chemistry, biology, pharmacology and
clinical perspectives Ed: P Braquet Prons Science Publishers, Barcelona, pp 391-404 (1990)
Fleming I, Furman BL, Gray G, Guc MO, Julou-Schaeffer G, Bigaud M, Stoclet J-C, Parratt
JR Mechanisms of vascular impairment during endotoxaemia with special reference to the
role of the L-arginine pathway In: Shock, sepsis & organ failure. The Second BernardWiggers Conference, ed H Reidl and G Schlag, Springer, Berlin, pp 399-420 (1991).
Vegh A, Szekeres L, Parratt JR Preconditioning: an early protective response to myocardial
ischaemia In: Myocardial response to acute injury Ed J R Parratt, London; Macmillan,
1992, pp110-127
Wainwright CL, Parratt JR Platelet derived substances in acute myocardial injury In:
Myocardial response to acute injury Ed J R Parratt, London:Macmillan, 1992, pp 128-140
Parratt JR, Stoclet JC Nitric oxide as a mediator of the vascular derangements of sepsis and
endotoxaemia. In: Mediators of Sepsis Eds M Lamy, L G Thijs, Springer, Berlin, 1992, pp
174-189.
Parratt JR, Harvey AL. The Strathclyde Institute for Drug Research: a model for
collaboration between universities and industry. In: The Pharmaceutical Industry in an
Extended Europe. Eds. F Ornskov and G Dukes. IBC, London, 1992, pp 93-98.
Parratt JR, Stoclet J-C, Fleming I. The role of L-arginine nitric oxide pathway in sepsis and
endotoxaemia with especial reference to vascular impairment. In: Pathophysiology of Shock,
Sepsis and Organ Failure. Eds. G Schlag, E Redl. Springer Verlag, Berlin 1993, pp575-592.
Parratt JR, Stoclet J-C, Furman BL. Substances mainly derived from vascular endothelium
(endothelium-derived relaxing factor, or nitric oxide, and endothelin) as chemical mediators
in sepsis and endotoxaemia. In: Handbook of Mediators of Septic Shock. Eds. E Neugebauer
and J W Holloday, CRC Press 1993, pp 381-393
Furman BL, Parratt JR. 5-Hydroxytryptamine as a chemical mediator of shock. In:
Handbook of Mediators in Septic Shock. Eds. E Neugebauer and J W Holloday, CRC Press
1993, pp 127-139
Parratt JR. Ischemic Preconditioning - A pronounced and endogenous form of protection
against tissue injury. In: 1994 Yearbook of Intensive Care and Emergency Medicine, ed. J C
Vincent, Berlin Springer, 1994, 279-289.
Parratt JR, Vegh A, Papp J Gy, Szekeres L. Nitric oxide generation, following activation of
bradykinin (B2) receptors, mediatrs the pronounced antiarrhythmic effects of ischaemic
preconditioning in anaesthetised dogs. In: Biology of Nitric Oxide, Volume 3, Physiological
and Clinical Aspects. Ed S Moncada, London Portland, 1994, pp 69-74.
Parratt JR (1995) Nitric oxide and cardiovascular dysfunction in sepsis and endotoxaemia:
An introduction and an Overview. In: Shock, Sepsis and Organ Failure - Nitric oxide (eds)
Schlag G, Redl H, Springer, 1-29.
Parratt JR, Stoclet JC (1995). Vascular smooth muscle function under conditions of sepsis
and endotoxaemia. In: Role of Nitric Oxide in Sepsis and ARDS, eds. M P Fink, D Payen,
Berlin: Springer, pp 44-61.
PARRATT JR (1996) The role of nitric oxide in the vascular derangements associated with
sepsis and endotoxaemia. In: Shock; From Molecular and Cellular Level to Whole Body
(eds) K Okada et al.,. Elsevier, Tokyo.pp 53-61.
PARRATT JR, VEGH A, KASZALA K and PAPP JGY (1996) Suppression of lifethreatening ventricular arrhythmias by brief periods of ischaemia and by cardiac pacing with
particular reference to delayed myocardial protection. In: Ischaemic preconditioning and
adaptation. (eds) MS Marber, DM Yellon. Bio Scientific Publishers, Oxford pp 85-111.
VEGH A and PARRATT JR (1996) Ischemic preconditioning markedly reduces the severity
of ischaemia and reperfusion-induced arrhythmias: role of endogenous myocardial protective
substances. In: Myocardial Preconditionining (eds) CL Wainwright and JR Parratt, Springer,
Berlin pp 35-60.
VEGH A and PARRATT JR (1996) Delayed ischemic preconditioning induced by drugs and
by cardiac pacing. In: Myocardial Preconditionining (eds) CL Wainwright and JR Parratt,
Springer, Berlin pp 251-260.
PARRATT JR (1997) Myocardial contractility and cardioprotection; importance of
endothelium-derived nitric oxide. In: Coronary microcirculation during ischaemia and
reperfusion. Eds. S Haunso, J Aldershvile, JH Svendsen, Monksgaard, pp 151-167.
FURMAN BL and PARRATT JR (1997) Eicosanoids, platelet activating factor and nitric
oxide as mediators of shock. In: Scientific Foundations of Trauma. Eds. GJ Cooper, HAF
Dudley, DS Gann, RA Little, RL Maynard. Butterworth, Heinemann pp 494-507.
PARRATT JR and VEGH A (1997) Coronary vascular endothelium, preconditioning and
arrhythmogenesis. In: Endothelial modulation of cardiac function (eds MJ Lewis, AM
Shah). Harwood Academic Publishers. pp 237-254.
ABSTRACTS
Parratt JR, West GB Tissue histamine and 5-hydroxytryptamine J Physiol (1956), 132, 4041P
Parratt JR, West GB Influence of age on tissue histamine and 5-hydroxytryptamine J Physiol
(1956), 133, 71-72P
Parratt JR, West GB The location and possible function of 5-hydroxytryptamine in the rat J
Physiol (1956), 134, 11-12P
Parratt JR, West GB Action of polymyxin B on tissue mast cells of the rat J Physiol (1956),
135, 24P
Parratt JR, West GB Inhibition of oedema production in the rat J Physiol (1956), 135, 24-25P
Parratt JR, West GB Oedema-producing substances in the rat J Physiol (1956), 135, 10-11P
Parratt JR Thyroxine and histamine release in the rat Journal of Physiology (1957), 138,
51-52P
Grayson J, Parratt JR The effect of bradykinin on blood flow and heat production in the rabbit
heart XXII International Congress of Physiological Sciences (1962), Abstract 81
Grayson J, Parratt JR The effect of haemorrhage on myocardial blood flow in monkeys, dogs
and rabbits J Physiol (1963), 169, 30-31P
Grayson J, Parratt JR Observations on blood flow in the myocardium Israel Journal of
Experimental Medicine, (1964), 11, 142
Parratt JR, Scholtholt J, Bussmann WD, Hirche Hj, Lochner W Die Wirkung von
Adeninnucleotiden und Plasmakininen auf die Coronarduchblutung und ihre Bedeutung bei
der physiologischen Regulation Pflugers Archiv (1965), 283, R54
Grayson J, Irvine M, Mendel D, Parratt JR A comparison of the effects of haemorrhage and
amyl nitrite inhalation on myocardial metabolic heat production J Physiol (1965), 181, 6869P
Grayson J, Parratt JR Myocardial vascular reactivity after beta-adrenergic blockade Lancet,
(1966), i, 338-340
Grayson J, Parratt JR Myocardial vascular reactivity Lancet, (1966) 1, 819
Ledingham IMcA, McBride TI, Parratt JR, Vance JP The effect of hypercapnia on
myocardial blood flow and oxygen consumption Journal of Physiology (1969), 200, 47-48P
Grayson T, Irvine M, Parratt JR The effects of carbochromen on myocardial blood flow and
metabolic heat production before and after acute coronary ligation Brit J Pharmac (1969),
37, 523-524P
Parratt JR, Wadsworth RM Myocardial and vascular effects of H56/28: Possible role as antianginal agent 4th International Congress on Pharmacology Abstracts of Communication
(1969) 277
Parratt JR, Wadsworth RM The effect of "selective" beta-receptor blocking drugs on the
myocardial circulation (1969) Br J Pharmac (1969) 37, 524P
Grayson J, Parratt JR Effects of coronary ligation on myocardial blood flow using a heated
thermocouple technique Biorheology 1970, 6, 344-345
Das PK, Parratt JR Myocardial effects of phentolamine Brit J Pharmac (1970) 40, 150-151P
Vance JP, Parratt JR, McBride TI, Ledingham I McA The effect of hypoxia on myocardial
blood flow and oxygen consumption Br J Anaes (1970), 42, 558
Ledingham IMcA, Parratt JR, Vance JP Effect of propranolol on hypoxia induced myocardial
vasodilation Brit J Pharmac (1971) 41, 389P
Moore G, Parratt JR The effect of catecholamines on myocardial blood flow after acute
coronary ligation J de Pharmacologie (1971), 2, 188-189
Parratt JR, Winslow E The effects of quazodine on myocardial blood flow in developing
myocardial infarcts J Pharm Pharmacol (1971) 23, Suppl, 224-225S
Ledingham IMcA, McArdle CS, Parratt JR Comparison of a coronary vasodilator drug
(carbochromen) and a cardiac stimulant (oxyfedrin) on blood flow and oxygen extraction in
experimental myocardial infarcts Brit J Pharmac (1972) 44, 323-324P
Fisher W, Heimbach D, Ledingham IMcA, Marshall RJ, Parratt JR Blood flow and oxygen
extraction in ischaemic and normal regions of the myocardium following acute coronary
artery ligation J Physiol (1973) 230, 15-17P
Ledingham IMcA, Marshall RJ, Parratt JR Drug-induced changes in blood flow in normal
and ischaemic regions of the canine myocardium Br J Pharmac (1973) 47, 626-627P
Ledingham IMcA, Marshall RJ, Parratt JR The effect of hyperbaric oxygen on myocardial
blood flow and oxygen consumption following acute coronary artery ligation J Physiol
Lond (1973) 231, 100-101P
Parratt JR Haemodynamic effects of prolonged oral administration of oxyfedrine NaunynSchmiedeberg's Archives of Pharmacology (1973) 229, Suppl R13
Parratt JR, Sturgess R The effect of indomethacin on the cardiovascular responses of cats to
E. coli endotoxin Brit J Pharmac (1973) 49, 163-164P
Marshall RJ, Parratt JR The effects of practolol in the early stages of experimental
myocardial infarction Br J Pharmac (1974), 52, 124P
Parratt JR, Sturgess RM Evidence that prostaglandin release mediates pulmonary
vasoconstriction induced by E coli endotoxin J Physiol (1975) 246, 79-80P
Parratt JR, Sturgess RM The protective effect of sodium meclofenamate in experimental
endotoxin shock Br J Pharmac (1975) 53, 466P
Al-Kaisi N, Parratt JR, Siddiqui HH, Zeitlin IJ The effect of E coli endotoxin on cat plasma
kininogen; modification by methylprednisolone J Physiol (1976) 256, 24-25P
Marshall RJ, Parratt JR The effects of dobutamine in the early stages of acute experimental
myocardial infarction in the dog Br J Pharmac (1976) 58, 407-408P
Ledingham IMcA, Marshall RJ, Parratt JR The effects of hyperbaric oxygen (2ATA) on the
haemodynamic, metabolic and electrocardiographic consequences of acute myocardial
ischaemia in anaesthetised greyhounds J Physiol (1977) 268, 16-17P
Parratt JR, Marshall RJ Antidysrhythmic and haemodynamic effects of disopyramide
phosphate (DP) in the early stages of canine myocardial infarction J Molec Cell Cardiol
(1978) 10, Suppl 1, 56
Kane KA, McDonald F, Parratt JR Coronary artery ligation in anaesthetised rats as a model
for the assessment of antidysrhythmic activity; the effects of lignocaine, propranolol and Org
6001 Br J Pharmac (1979) 66, 463-464P
Coker SJ, Marshall RJ, Parratt JR, Siddiqui HH, Zeitlin IJ Do prostaglandins or kinins play
any role in the genesis of post-coronary artery occlusion arrhythmias? J Molec Cell
Cardiology (1979) 11, Suppl 2,8
Parratt JR, Saleh S, Waton NG The effect of endotoxin shock on histamine and histidine
decarboxylase enzyme activities in various tissues of cats Br J Pharmac (1980) 69, 308P
Parratt JR, Udvary E The effect of MG 8823, a new beta-adrenoceptor blocking agent, on
epicardial ST-segment changes in a feline model of acute myocardial ischaemia Br J
Pharmac (1980), 70, 65-66P
Hughes B, Madan BR, Parratt JR Polymyxin B sulphate markedly reduces the effects of E
coli endotoxin in anaesthetized cats Br J Pharmac (1980) 70, 100-101P
Coker SJ, Parratt JR The effects of prostacyclin on infarct flow and epicardial ST-segment
elevation in anaesthetized dogs Br J Pharmac (1980) 70, 86-87P
Kane KA, McDonald FM, Parratt JR What pharmacological properties are necessary for the
prevention of early post-infarction ventricular dysrhythmias? Br J Pharmac (1981) 72, 512513P
Coker, SJ, Ledingham IMcA, Parratt, JR, Zeitlin, IJ Aspirin inhibits both the early
myocardial release of thromboxane B2 and ventricular ectopic activity following acute
coronary artery occlusion in dogs Scot Med J (1981) 26, 169-170
Fagbemi O, Parratt JR Marked suppression by nifedipine, niludipine and nisoldipine of
ventricular fibrillation resulting from acute myocardial ischaemia Br J Pharmac (1981) 74,
830-831P
Coker SJ, Hughes B, Parratt JR, Rodger IW, Zeitlin IJ Prostaglandin F2a, thromboxane and
the acute response to E coli endotoxin in anaesthetized cats Br J Pharmac (1981) 74, 792793P
Coker SJ, Ledingham IMcA, Parratt JR, Zeitlin IJ Thromboxane B2 and 6-keto PGF1a
release into coronary venous effluent: effect of coronary artery occlusion J Physiol (1981)
316, 12P
Coker SJ, Ledingham IMcA, Parratt JR, Zeitlin IJ Ventricular fibrillation resulting from
reperfusion of the acutely ischaemic canine myocardium is prevented by the thromboxane
synthetase inhibitor UK 37, 248 Scot Med J (1982) 27, 193
Adeleye GA, Furman BL, Parratt JR Possible involvement of opiate receptors in the response
of conscious rats to Escherichia coli endotoxin; protective effect of naloxone J Physiol
(1982) 329, 31P
Fagbemi O, Lepran I, Parratt JR, Szekeres L Naloxone inhibits early post-infarction
arrhythmias; possible detrimental role of beta-endorphin? Br J Pharmac (1982) 76, 178P
Coker SJ, Ledingham IMcA, Parratt JR, Zeitlin IJ Inhibition of thromboxane synthesis with
UK 37,248 prevents fibrillation following reperfusion of the ischaemic myocardium Br J
Pharmac (1982) 76, 221P
Ball H, Parratt JR, Zeitlin IJ Thromboxane and the pulmonary hypertensive response to
endotoxin Br J Pharmac (1982) 76, 285P
Adeleye GA, Furman BL, Parratt JR Role of kinins in the metabolic effects of endotoxin Br
J Pharmac (1982) 76, 286P
Harris N, Kane KA, Parratt JR Autonomic and hormonal influences on the severity of
coronary artery ligation-induced arrhythmias in anaesthetized rats Br J Pharmac (1982) 77,
388P
Kane KA, Parratt JR, Williams FM Reperfusion-induced cardiac arrhythmias in the
anaesthetized rat and their susceptibility to drugs Br J Pharmac (1983) 78, 122P
Coker SJ, Parratt JR Different effects of intravenous and intracoronary prostacyclin and ZK
36374 on cardiac arrhythmias in anaesthetized dogs Br J Pharmac (1983) 78, 31P
Fagbemi O, Kane KA, Lepran I, Parratt JR, Szekeres L
Antiarrhythmic and
electrophysiological effects of meptazinol Br J Pharmac (1983) 78, 121P
Ball H, Parratt JR, Rodger,IW Effects of dazoxiben, a thromboxane synthetase inhibitor, on
the airways and pulmonary vascular response to E coli endotoxin Br J Pharmac (1983) 79,
346P
Parratt JR, Wainwright, CL Antiarrhythmic effects of metoprolol related to the time of
administration Br J Pharmac (1983) 79, 362P
Coker SJ, Parratt JR Nafazatrom, prostacyclin and ZK 36374 suppress reperfusion-induced
ventricular fibrillation in anaesthetized greyhounds Br J Pharmac (1983) 79, 237P
Kane KA, Parratt JR, Rochette L, Williams FM Nicergoline reduces ventricular arrhythmias
induced by myocardial ischaemia and reperfusion Naunyn-Schiedeberg's Arch Pharmacol
(1983) 324, R39
Evis MJ, Kane KA, Moore MR, Parratt JR The effects of chronic low level lead preteatment
on the severity of cardiac arrhythmias following coronary artery ligation in the anaesthetised
rat J Mol Cell Cardiol (1983) 15, Suppl 1, 178
Fagbemi O, Kane KA, McDonald FM, Parratt JR, Rothaul A The effects of flunarizine,
prenylamine and verapamil on coronary artery ligation induced arrhythmias in the
anaesthetised rat J Mol Cell Cardiol (1983) 15, Suppl 1, 179
Parratt JR, Wainwright CL Beta-adrenoceptor blockade, with or without a thromboxane
synthetase inhibitor, or ischaemic arrhythmias J Mol Cell Cardiol (1983) 15, Suppl 1, 346
Kane KA, Parratt JR, Williams FM A model for reperfusion-induced cardiac arrhythmias in
the anaesthetised rat J Mol Cell Cardiol (1983) 15, Suppl 1, 415
Coker SJ, Parratt JR The effects of timolol on arrhythmias and prostanoid release during
acute myocardial ischaemia and reperfusion in anaesthetised greyhounds J Mol Cell Cardiol
(1983) 15, Suppl 1, 416
Kane KA, Parratt JR, Rothaul AL Effects of prazosin and nicergoline on normal and mildly
depressed sheep Purkinje fibre action potentials Br J Pharmac (1984), 82, 331P
Coker SJ, Parratt JR Antiarrhythmic activity of the thromboxane antagonist AH 23848
during canine myocardial ischaemia and reperfusion Br J Pharmac (1984), 83, 380P
Evis M, Kane KA, Moore MR, Parratt JR The effects of high blood pressure and chronic low
level lead pre-treatment, alone and in combination, on the severity of ischaemia induced
arrhythmias in anaesthetised rats J Mol Cell Cardiol (1984), 16, Suppl 2, Abstract 56
Wainwright CL, Parratt JR, Lepran I, Szekeres L, Bullock GR Protective effects of a
metropolol thromboxane synthetase inhibitor combination on myocardial damage during
acute myocardial ischaemia J Mol Cell Cardiol (1984), 16, Suppl 2, Abstract 110
Williams FM, Kane KA, Parratt JR The antiarrhythmic activity of ICS 205-930, an
antagonist at peripheral neuronal 5-hydroxytryptamine (5-HT) receptors J Mol Cell Cardiol
(1984), 16, Suppl 2, Abstract 116
Coker SJ, Parratt JR Late administration of nifedipine fails to prevent reperfusion-induced
ventricular fibrillation in anaesthetised greyhounds Br J Pharmac (1984), 82, 214P
Lepran I, Parratt JR, Szekeres L, Wainwright CL Antiarrhythmic effects of a metroprolol
thromboxane synthesis inhibitor combination in conscious rats Br J Pharmac (1984) 82,
225P
Ball HA, Parratt JR Effects of a new thromboxane receptor antagonist, AH23848, on the
acute cardiopulmonary responses to E coli endotoxin in cats Br J Pharmac (1984), 83, 379P
Parratt JR Eicosanoids and cardiac arrhythmias resulting from myocardial ischaemia and
reperfusion J Mol Cell Cardiol (1985), 17, Suppl 3, 178
Coker SJ, Parratt JR
Does inhibition of thromboxane synthesis account for the
antiarrhythmic activity of aspirin in canine myocardial ischaemia and reperfusion J Mol
Cell Cardiol (1985), 17, Suppl 3, Abs 109
Furman BL, McKechnie J, Parratt JR Effect of antioxidants on endotoxin shock in conscious
unrestrained rats Br J Pharmac (1985), 84, 119P
Evis MJ, Kane KA, Moore MJ, Parratt JR Effects of chronic low level lead treatment and
hypertension on the severity of coronary artery ligation induced arrhythmias Br J Pharmac
(1985), 84, 32P
Coker SJ, Kane KA, Parratt JR, Williams FM The effects of nicergoline, an alphaadrenoceptor blocking drug, on ischaemia and
reperfusion-induced arrhythmias in
anaesthetised dogs Br J Pharmac (1985), 84, 30P
Parratt JR, Wainwright CL The effects of adenosine on arrhythmias induced by myocardial
ischaemia and reperfusion in dogs Br J Pharmac (1985), 85, 228P
Parratt JR Eicosanoids and susceptibility to ventricular arrhythmias during myocardial
ischaemia & reperfusion J Mol Cell Cardiol (1986), 18, Suppl 1, Abstract 79
Bryson SE, McKechnie K, Pacitti N, Parratt JR, Rodger, IW Effect of leukotriene antagonist
FPL57231 on the acute phase of endotoxin shock in cats Br J Pharmac (1986), 88, 230P
Parratt JR, Wainwright CL Ventricular arrhythmias induced by local injections of
vasoconstrictors following coronary occlusion Br J Pharmac (1986), 88, 397P
Parratt JR, Wainwright CL The effects of the thromboxane antagonist BM13177 on
ischaemia and reperfusion induced arrhythmias in dogs Br J Pharmac (1986), 88, 291P
Boachie-Ansah G, Kane KA, Parratt JR Effects of adenosine, ATP and noradrenaline on
normal and mildly 'ischaemic' sheep cardiac purkinje action potentials Br J Pharmac (1986)
88, 309P
Parratt JR, Wainwright CL, Coker SJ Modifications of the thromboxane/prostacyclin balance
an approach for antiarrhythmic therapy during myocardial ischaemia and reperfusion J Mol
Cell Cardiol (1986) 18, Suppl3, 54
MacKenzie JE, Parratt JR, Sitsapesan R The antiarrhythmic properties of naloxone and
Mr2593 (naloxone methobromide) in vivo and in vitro Br J Pharmac (1986), 89, 613P
MacKenzie JE, Parratt JR, Sitsapesan R The effects of drugs interacting with opioid
receptors on ischaemic arrhythmias in anaesthetised rats Br J Pharmac (1986), 89, 614P
McHarg AD, Parratt JR, Wadsworth RM The effect of amlodipine, nifedipine and diltiazem
on Ca++ contractions of canine coronary artery rings Br J Pharmac (1986) 89, 539P
Dashwood MR, Parratt JR, Spyer KM, Wainwright CL Autoradiographic demonstration of
changes in alpha-adrenoceptor and muscarinic receptor density in ischaemic rat heart Br J
Pharmac (1987) 91, 510P
Parratt JR, Coker SJ, Wainwright CL Eicosanoids and susceptibility to ventricular
arrhythmias during myocardial ischaemia and reperfusion J Mol Cell Cardiol (1987) 19,
Suppl 5, 55-66
Dashwood MR, Millo J, Parratt JR, Spyer KM, Wainwright, CL An autoradiographic
investigation of beta-adrenoceptor distribution in normal and ischaemic rat myocardium J
Physiol (1987) 392, 76P
Fagbemi O, Parratt JR, Wainwright CL, Zeitlin IJ Enzymic release of hypotensive and
spasmogenic activity in dog hearts J Physiol (1987) 392, 93P
Fagbemi O, Parratt JR, Wainwright CL The effects of dopexamine and dopamine in
myocardial ischaemia Br J Pharmac (1987) 91, 352P
Gray GA, Furman BL, Parratt, JR Endotoxin-induced impairment of vascular reactivity in he
pithed rat Br J Pharmac (1987) 92, 644P
Bigaud M, Wainwright CL, Parratt JR, Stoclet JC Studies on the behaviour of platelets
during acute myocardial ischaemia and reperfusion Br J Pharmac (1988) 93, 257P
Gray GA, Furman BL, Parratt JR Impairment of vascular reactivity in the rat by endotoxin in
vivo but not ex vivo Circulat Shock (1988) 24, Abstract 18 (page 199)
Pacitti N, Parratt JR. The prostacyclin analogue iloprost abolishes the early pulmonary
effects of endotoxin Circulat Shock (1988) 24, Abstract 33 (pages 204-205)
Wainwright CL, Parratt JR, Bigaud M, Stoclet JC Effects of PAF antagonists on platelet
behaviour and arrhythmias during myocardial ischaemia Prostaglandins (1988) 35, 809
Parratt JR, Wainwright CL Inhibition of cyclooxygenase during acute myocardial ischaemia
and reperfusion Eur Heart J (1988), 9, abstract Suppl 1, P206
Wainwright CL, Parratt JR, Bigaud M PAF, arrhythmias and platelet aggregation during
myocardial ischaemia Eur Heart J (1988) 9, Suppl 1, P161
Parratt JR, Wainwright CL Studies on PAF antagonists during acute myocardial ischaemia
and reperfusion J Molec Cell Cardiol (1988) 20, Suppl 2, S27
Bigaud M, Stoclet JC, Parratt JR Implications of calcium in endotoxin-induced impairment
of rat aortic constriction ex vivo Br J Pharmac (1989) 96, 150P
Boachie-Ansah G, Kane KA, Parratt JR The cardiac electrophysiological effects of
dopexamine under normal and simulated ischaemic conditions J Molec Cell Cardiol (1989)
21, Suppl II, S23
Wainwright CL, Parratt, JR Cyclooxygenase inhibition fails to protect against ischaemia and
reperfusion-induced arrhythmias J Molec Cell Cardiol (1989) Suppl II S148
Wainwright CL, Parratt JR, Bigaud M, Tweddel A, Martin W Platelet, blood flow and
electrocardiographic changes during acute myocardial ischaemia J Molec Cell Cardiol
(1989) Suppl II, S113
Julou-Schaeffer G, Parratt JR, Schott C, Stoclet JC Influence of in vivo endotoxin treatment
on endothelin-induced contractions of the rat isolated aorta J Physiol Lond (1989) 417, 66P
Moshi MJ, Parratt JR, Wainwright CL, Zeitlin IJ Acid optimum kinin-forming enzymes in
dog cardiovascular tissues J Physiol (1989) 418, 177P
Gray GA, Furman BL, Parratt JR Platelet activating factor and endotoxin-induced depression
of vascular reactivity Br J Pharmac (1989) 97, 526P
Guc MO, Furman BL, Gray GA, Parratt JR Endotoxin depresses vascular reactivity to
phenylephrine, clonidine and BAY K8644 but not to endothelin Br J Pharmac (1989) Suppl
98, 628P
Parratt JR Arrhythmogenesis during ischaemia and reperfusion - a pharmacologists
viewpoint J Molec Cell Cardiol (1989), 21, Suppl IV, L20
Komori S, Parratt JR, Szekeres L, Vegh A Preconditioning reduces the severity of ischaemia
and reperfusion-induced arrhythmias in both anaesthetised rats and dogs J Physiol London
(1990) 423, 16P
Fleming I, Gray GA, Julou-Schaeffer G, Parratt JR, Schott C, Stoclet JC Impaired vascular
reactivity in the rat following endotoxin treatment can be endothelium-independent, yet
involves the L-arginine pathway J Physiol London (1990), 423, 18P
Gray GA, Fleming I, Julou-Schaeffer G, Parratt JR, Stoclet J-C Endothelial function is
impaired in aortae from lipopolysaccharide (LPS)- treated rats J Mol Cell Cardiol (1990) 22,
(Suppl III) S8
Fleming I, Gray GA, Julou-Schaeffer G, Parratt JR, Stoclet J-C Incubation with endotoxin
(ETX) induces vascular hyporeactivity which is reversed by NGmonomethyl-L-arginine (LNMMA) J Mol Cell Cardiol (1990) 22, (Suppl III) S10
McIntosh MA, Kane KA, Parratt JR The effects of opioid receptor selective antagonists and
agonists following coronary artery occlusion in anaesthetised rats J Mol Cell Cardiol (1990)
22, (Suppl III) S72
Komori S, Tamura K, Parratt JR Protective effect of preconditioning of myocardial
ischaemia in coronary ligation induced arrhythmias of rats J Mol Cell Cardiol (1990) 22,
(Suppl III) S76
Vegh A, Szekeres L, Parratt JR Role of time in the protective effect of preconditioning J
Mol Cell Cardiol (1990) 22, (Suppl III) S77
Wainwright CL, Parratt JR Electrocardiographic and haemodynamic effects of myocardial
preconditioning in pigs J Mol Cell Cardiol (1990) 22, (Suppl III) S77
Wainwright CL, Parratt JR, van Belle H The antifibrillatory effects of R75231, a specific
nucleoside transport inhibitor J Mol Cell Cardiol (1990) 22, (Suppl III) S77
Robertson E, Parratt JR The effects of inotropic stimulation on the occurrence of arrhythmias
in experimental myocardial infarction J Mol Cell Cardiol (1990) 22, (Suppl III) S78
Robertson E, Parratt JR A comparison of the effects of two positive inotropic agents, DP1
201-106 and isoprenaline, on early ischaemic arrhythmias J Mol Cell Cardiol (1990) 22,
Suppl III) S78
McIntosh M, Kane KA, Parratt JR The cardiac electrophysiological effects of opioid receptor
selective antagonists J Mol Cell Cardiol (1990) 22, (Suppl III) S81
Furman BL, Guc MO, Parratt JR Similarities between endotoxin and nicardipine in
impairing vascular reactivity Circulatory Shock (1990) 31, 224P
Gray GA, Julou-Schaeffer G, Oury K, Fleming I, Parratt JR, Stoclet J-C Endotoxin-induced
impairment of vascular smooth muscle sensitivity to calcium is restored by NG-monomethylL-arginine (L-NMMA) Circulatory Shock, (1990) 31, 225P
Guc MO, Furman BL, Parratt JR Anti-tumour necrosis factor antibody prevents endotoxininduced impairment of vasodepressor responsiveness to 5-hydroxytryptamine Circulatory
Shock (1990) 31, 232
Gray GA, Fleming I, Julou-Schaeffer G, Parratt JR, Stoclet JC NG monomethyl-L-arginine
restores pressor responses to noradrenaline in endotoxin-treated rats Br J Pharmacol (1990)
99, 107P
Guc MO, Furman BL, Gray GA, Parratt JR Endotoxin depresses vascular reactivity to
vasodilators in the pithed rat Br J Pharmacol (1990) 99, 47P
Moshi MJ, Zeitlin IJ, Parratt JR Acid optimum (ACOP) kinin-forming enzyme in rat
ventricular myocardium Proc IUPHAR Conference, Amsterdam, July 3rd Eur J Pharmacol
(1990) 183, 702
Vegh A, Szekeres L, Parratt JR Preconditioning of the ischaemic myocardium: role of the
cyclooxygenase pathway Br J Pharmacol (1990) 99, 19P
Wainwright CL, Parratt JR, van Belle H The effects of nucleoside transport inhibitor,
R75231, on ischaemic arrhythmias in anaesthetised pigs Br J Pharmacol (1990) 99, 19P
Fleming I, Gray GA, Parratt JR, Stoclet J-C LPS-induced activation of the L-arginine/NO
pathway in endothelium denuded arterial tissue is time dependent and requires de novo
protein syntheses Br J Pharmacol (1991) 102, 123P
Vegh A, Szekeres L, Parratt JR Preconditioning of the ischaemic myocardium effect of Nw
nitro-L-arginine methyl ester (L-NAME) Br J Pharmacol (1991) 102, 124P
Gray GA, Fleming I, Parratt JR, Stoclet J-C L-arginine dependent accummulation of cyclic
GMP in rat aortic medial smooth muscle layer incubated with lipopolysaccharide Br J
Pharmacol (1991) 102, 122P
Guc O, Furman BL, Parratt JR Reversal of endotoxin-induced impairment of responsiveness
to sympathetic stimulated by L-nitroarginine methyl ester and vasopressin in pithed rats Br J
Pharmacol (1991) 102, 320P
Parratt JR, Szekeres L, Vegh A Preconditioning and arrhythmogenesis J Mol Cell Cardiol
(1991) 23 (Suppl V) S34
Vegh A, Szekeres L, Parratt JR Does nitric oxide play a role in ischaemic preconditioning? J
Mol Cell Cardiol (1991) S72
Parratt JR, Furman BL, Bouvier C Endotoxin induced loss of vascular responsiveness; role
of platelet activating factor Circulatory Shock (1991) 34, Abstract 375
Tweddel AC, Martin W, Wainwright C, Parratt J, Cobbe SM Platelet and white cells in early
infarction Eur Heart J (1991) 12, Abstract 1562
Wainwright CL, Parratt JR Preconditioning of the ischaemic myocardium in pigs - an
antiarrhythmic phenomenon? Eur Heart J (1991) 12, Abstract 1565
Wainwright CL, Parratt JR The effects of R-PIA, and A1-adenosine receptor agonist, on
ischaemic arrhythmias in pigs Eur Heart J (1991) 12, Abstract 1776
Wainwright CL, Parratt JR The effects of CV1808, an A2-adenosine receptor agonist, on
ischaemic arrhythmias in anaesthetised pigs Br J Pharmacol (1991) 104, 20P
McIntosh MA, Kane KA, Parratt JR The effects of opioid peptides on cardiovascular and
sympathetic neurotransmission in rats Br J Pharmacol (1991) 104, 186P
Guc MO, Furman BL, Parratt JR Differences between endotoxin and sodium nitroprusside in
impairing vascular reactivity Circulatory Shock (1991) 34, Abstract 129
Vegh A, Szekeres L, Parratt JR Nitric oxide involvement in preconditioning of the ischaemic
myocardium in anaesthetized dogs. J Physiol (1992) 446, 541P
Vegh A, Szekeres L, Szilvassy Z, Parratt JR Myocardial preconditioning in anaesthetised
dogs can be induced by rapid cardiac pacing. J Physiol (1992) 446, 218P
Parratt JR, Vegh A, Szekeres L, Papp Gy. Profound antiarrhyhtmic effects of ischaemic
preconditioning - a role for endogenous myocardial protective substances. J Mol Cell Cardiol
(1992) 24 (Suppl II), S.6.
Vegh A, Szekeres L, Parratt JR. Inhibition of nitric oxide production in anaesthetised dogs
fails to modify work-induced increases in coronary blood flow. J Physiol (1992) 452, 16P.
Wainwright CL, ParrattJR, Tweddel AC, Martin W, Cobbe S. Adenosine and an A2 agonist,
CGS21680, reduce arrhythmias and suppress white cell accumulation in the porcine
ischaemic myocardium. Br J Pharmacol (1992) 107, 97P.
Piacentini L, Wainwright CL, Parratt JR. The antiarrhythmic effects of preconditioning, in
rat isolated hearts, does not involve A1 adenosine receptors. Br J Pharmacol (1992) 107,
137P.
Sun W, Wainwright CL, Parratt JR. The BK2 antagonist, HOE 140, does not attenuate the
antiarrhythmic effect of ischaemic preconditioning in anaesthetised rats. Br J Pharmacol
(1992) 107, 138P.
Vegh A, Parratt JR, Szekeres L, Papp J Gy. Does nitric oxide play a role in compensatory
vasodilatation? J Mol Cell Cardiol (1992) 24; (Suppl V) S51.
Piacentini L, Wainwright C, Parratt J. Prevention of the antiarrhythmic effects of ischaemic
preconditioning by pertussis toxin pretreatment. J Mol Cell Cardiol (1992) 24 (Suppl V);
S92.
Vegh A, Szekeres L, Papp J Gy, Parratt JR. Preconditioning of the ischaemic myocardium is
reversed by methylene blue; further evidence for the role of cGMP? J Mol Cell Cardiol
(1992) 24 (Suppl V), S88.
Vegh A, Szekeres L, Papp J Gy, Parratt JR. Are KATP channels involved in the profound
antiarrhythmic effects of preconditioning in anaesthetised dogs. Br J Pharmacol (1992)
274P.
Laycock SK, Kane KA, McMurray J, Parratt JR. The purine-xanthine oxidase system does
not depress myocardial function through a free radical mechanism. Br J Pharmacol (1992)
107, 131P.
Wainwright CL, Parratt JR. The antiarrhythmic effects of the A1-adenosine agonist R-PIA
are mediated by bradycardia. Br J Pharmacol (1992) 105, 117P.
Wainwright CL, Parratt JR, Tweddel AC, Martin W, Cobbe SM. Adenosine and an A2
agonist suppress arrhythmias and white cell accumulation in the porcine myocardium. Br J
Pharmacol (1992) 107, 97P.
Vegh A, Szekeres L, Parratt JR. Compensatory metabolic vasodilation in the coronary
vascular bed; effect of L-NAME. J. Physiol (in press).
Koide A, Zeitlin IJ, Parratt JR. Kinin formation in ischaemic heart and aorta of rats. J
Physiol Lond, (1993) 467, 125P.
Vegh A, Parratt JR. The possible role of plasma kinins and nitric oxide in myocardial
protection under conditions of ischaemia and preconditioning. J Mol Cell Cardiol (1993) 25,
S113.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. The pronounced antiarrhythmic effects of
bradykinin are abolished by an inhibitor of the L-arginine nitric oxide pathway. J Mol Cell
Cardiol (1993) 25, S76.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. Is there a role for bradykinin in ischaemic
preconditioning? J Mol Cell Cardiol (1993) 25, S34.
Parratt JR, Stoclet J-C. Mechanisms of the loss of vascular responsiveness in sepsis and
endotoxaemia. Circulatory Shock (1993) Suppl 1, 8.1.
Fatehi-Hassanabad Z, Furman BL, Parratt JR. Impairment of endothelium-dependent
vasodilator responses in perfused mesenteric beds isolated from endotoxin treated rats.
Circulatory Shock (1993) Suppl 1, 8.5
Burns HO, Furman BL, Parratt JR. Comparison of methylene blue and L-canavanine on
endotoxin-induced impairment of vascular reactivity. Circulatory Shock (1993) Suppl 1, 8.6
Parratt J, Vegh A, Papp J Gy, Szekeres L. Bradykinin triggered nitric oxide release accounts
for the pronounced antiarrhythmic effects of ischaemic preconditioning in anaesthetised dogs.
J Endothelial Cell Res (1993) 12, Suppl . abs 246.
Burns HO, Furman BL, Parratt JR. Effects of L-canavanine on E. colo endotoxininducedshock in the anaesthetised rat. Br J Pharmacol (1993) 130P.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. Evidence that bradykinin contributes to the
pronounced antiarrhythmic effects of ischaemic preconditioning. Br J Pharmacol (1994) 111,
193P.
Piacentini L, Wainwright CL, Parratt JR. The antiarrhythmic effect of preconditioning, in
anaesthetised rats, does not depend on pertussis toxin-sensitive G1 proteins. Br J Pharmacol
(1994) 111, 29P.
Boachie-Ansah G, Kane KA, Parratt JR. Cicletanine-induced abbreviation of cardiac action
potential: a role for KATP channels. Br J Pharmacol (1994) 111, 115P.
Ravingerova T, Pyne NJ, Parratt JR. Adrenergic stimulation protects rat hearts against severe
arrhythmias: relevance to ischaemic preconditioning. J Molec Cell Cardiol (1994) 26, 467P.
Vegh A, Papp J Gy, Parratt JR. Intracoronary noradrenaline suppresses ischaemia-induced
arrhythmias in anaesthetised dogs. J Mol Cell Cardiol (1994) 26, 343P.
Vegh A, Papp J Gy, Szekeres L, Kasala K, Parratt JR. Antiarrhythmic effects of ischaemic
preconditioning during the 'second window of protection'. J Mol Cell Cardiol (1994) 26,
346P.
Kolar F, Parratt JR. Antiarrhythmic effect of ischaemic preconditioning in hearts of
spontaneously hypertensive rats. J Mol Cell Cardiol (1994) 26, 519P.
Vegh A, Papp J Gy, Kasala K, Parratt JR. Cardiac pacing in anaesthetized dogs preconditions
the heart against arrhythmias when ischaemic is induced 24 h later. J Physiol (1994) 480,
89P.
Wu Song, Furman BL, Parratt JR. Lipopolysaccharide (endotoxin) administration results in a
delayed protection against ischaemia-induced arrhythmias in rat isolated hearts. J Physiol
(1994) 480, 89P.
Fatehi-Hassanabad Z, Furman BL, Parratt JR. Endotoxin impairs the respone to nerve
stimulation of the rat isolated perfused mesenteric bed. Br J Pharmacol 1994, 112:206P.
Fatehi-Hassanabad Z, Furman BL, Parratt JR. Effects of endotoxin on reactive hyperaemia in
the rat mesenteric bed. Shock (1994) 2 (Suppl):26.
Fatehi-Hassanabd Z, Furman BL, Parratt JR. Effects of endotoxin on rat mesenteric blood
flow and responses to acetylcholine and noradrenaline. Shock (1994) 2(Suppl):33.
Laycock SK, Kane KA, McMurray J, Parratt JR. The differential effect of captopril on the
cardiac hypertrophic and inotrophic effects of chronic noradrenaline treatment in rats. Br J
Pharmacol (1994) 112:36P
Nagy S, Kaszaki J, Wolfard A, Parratt JR. Effect of inhibition of nitric oxide synthase on
myocardial contractility and cardiac output in hyperdynamic endotoxemia. Shock 2 (1994)
Suppl: 21.
Ravingerova T, Pyne NJ, Parratt JR. Adrenergic stimulation protects the rat heart against
severe ventricular arrhythmias: relevance to the mechanisms of ischaemic preconditioning.
Int. Con on Cellular Interactions in Cardiac Pathophysiology, Bratislava, (1994) P78-79.
Ravingerova T, Pyne NJ, Parratt JR. Ischaemic preconditioning in the rat heart: the role of Gproteins. Int. Con on Cellular Interactions in Cardiac Pathophysiology, (1994) P77.
Ravingerova T, Pyne NJ, Parratt JR. Ischaemic preconditioning (PC) in the rat heart: the role
of cell signalling. Physiological Research.
Sun W, Wainwright CL, Parratt JR. The antiarrhythmic effect of ischaemic preconditioning
is not prevented by inhibition of endothelium-derived nitric oxide in anaesthetised rats. Br J
Pharmacol (1994) 112: 380P.
Vegh A, Papp J Gy, Szekeres L, Parratt JR. Blocking adenosine receptors fails to modify the
pronounced antiarrhythmic effect of ischaemic preconditioning in the canine myocardium. Br
J Pharmacol (1994) 112: 399P
Wu Song, Furman BL, Parratt JR. Lipopolysaccharide (endotoxin) administration results in a
delayed protection against ischaemia-induced arrhythmias in rat isolated hearts. J Physiol
(1994) 480:89P.
Wu Song, Furman BL, Parratt JR. Endotoxin protects against ischaemia-induced arrhythmias
in the ex-vivo perfused rat hearts. Shock (1994) 2 (Suppl):20.
Ahmad M, Zeitlin IJ, Parratt JR. The effect of ischaemia on kinin release by isolated hearts
from normotensive (WKY) and spontaneously hypertensive (SHR) rats. J Physiol (1995)
483:21P.
Fatehi-Hassanabad Z, Furman BL, Parratt JR (1995). Endotoxin-induced impairment of
responses to sympathetic nerve stimulation. Shock 3, 126.
Fatehi-Hassanabad Z, Parratt JR, Furman BL (1995) Effects of endotoxin on the reactive
hyperaemia in the rat mesenteric bed. Shock 46
Fatehi-Hassanabad Z, Furman BL, Parratt JR (1995) Effects of endotoxin on the rat
mesenteric blood flow and responses to acetylcholine and noradrenaline. Shock (1995) 76
Humphreys RA, Kane KA, Parratt JR (1995) The influence of age and hormonal status on
myocardial ischaemic preconditioning. J Moll Cell Cardiol A147.
Humphreys RA, Kane KA, Parratt JR (1995) The effect of lodoxamide, a cardiac mast cell
stabiliser, on myocardial ischaemic preconditioning in the rat. Br J Pharmacol, 287P.
Kaszaki J, Wolfard A, Balogh Z, Parratt JR, Nagy S (1995) The role of nitric oxide in the
early hemodynamic changes in hyperdynamic endotoxemia. Shock 3 (Suppl) 26.
Kaszaki J, Boros M, Baranyi L, Wolfard A, Webb Z, Parratt JR, Nagy S (1995) The role of
nitric oxide and endothelins in the early hemodynamic changes in hyperdynamic
endotoxemia. Shock 4 (Suppl) 48-49.
Kaszala K, Vegh A, Papp J Gy, Gyorgy K, Parratt JR (1995) Local administration of
potassium channel openers and ischaemia-induced ventricular arrhythmias. Br J Pharmacol
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Kaszala K, Vegh A, Parratt JR. Time course of pacing-induced preconditioning in dogs. J
Molec Cell Cardiol 1995, A145.
Kis A, Vegh A, Papp J Gy, Parratt JR. Dual blockade of the cyclo-oxygenase and L-argininenitric oxide pathways prevents the antiarrhythmic effect of preconditioning. J Molec Cell
Cardiol 1995, A159.
Ostadalova I, Kolar F, Ostadal B, Parratt JR. (1995) Ischaemic preconditioning in neonatal
rat hearts.
Parratt JR, Vegh A, Semeraro C, Papp J Gy (1995) Beneficial effects of Z1046, a selec tive
dopamine receptor agonist, during myocardial ischaemia. Br J Pharmacol, 286P.
Parratt JR (1995) Mechanisms of vascular failure resulting from sepsis and endotoxaemia.
Shock 3, 112.
Parratt JR (1995) Nitric oxide and cardiovascular derangements in sepsis and endotoxaemia.
J Mol Cell Cardiol 27, A324.
Parratt JR (1995) Nitric oxide and cardiovascular derangements in sepsis and in
endotoxaemia. J Shock 4, Suppl, 5-1.
Ravingerova T, Ziegelhoffer A, Parratt JR. Antiarrhythmic effect of acute stimulation of rat
heart with exogenous norepinephrine (NE): The role of Na/K ATPase. J Molec Cell Cardiol
(1995) A162.
Ravingerova T, Wu Song, Ziegelhoffer A, Parratt JR, Pancza D, Vrbjar N, Dzurba A (1995)
Pretreatment with catecholamines can suppress severe ventricular arrhythmias in rats:
relevance to ischaemic preconditioning.
Ravingerova T, Wu Song, Ziegelhoffer A, Parratt JR (1995) Delayed antiarrhythmic effects
of pretreatment with norepinephrine in rats: The role of Na/K ATPase. J Mol Cell Cardiol,
A162.
Vegh A, Papp J Gy, Parratt JR (1995) Suppression of ischaemia-induced ventricular
arrhythmias by the local intracoronary administration of noradrenaline. Br J Pharmacol,
250P.
Vegh A, Kaszala K, Papp J Gy, Parratt JR (1995) Delayed myocardial protection by pacinginduced preconditioning: a possible role for bradykinin. Br J Pharmacol, 288P.
Vegh A, Kaszala K, Papp J Gy, Parratt JR (1995) Bradykinin, A trigger for delayed pacinginduced preconditioning. J Mol Cell Cardiol 27, A279.
Wilson S, Ravingerova T, Sakai K, Vegh A, Pyne N, Parratt JR. Protein kinase C-e is
downregulated by ischaemic preconditioning in the canine myocardium. J Molec Cell
Cardiol (1995) A157.
Wu Song, Furman BL, Parratt JR (1995) Effects of endotoxin on ischaemia-induced
arrhythmias and myocardial injury in rats. Shock 3, 100.
Wu Song, Furman BL, Parratt JR (1995) Mechanisms of reduction of ischaemia-induced
arrhythmias by endotoxin in the ex vivo perfused rat heart. Br J Pharmacol 114, 254P.
AHMAD M, ZEITLIN IJ, PARRATT JR, VALEN G, TAKESHIMA S and VAAGE J.
(1996) Changes in bradykinin levels in the blood of patients undergoing cardiopulmonary
bypass (CPB). J Physiol 494, 116P.
Fatehi-Hassanabad Z, Aughey E A, Parratt JR and Furman B L (1996). L - canavanine
reduces endotoxin - induced tissue damage in the rat. Shock 5: (Suppl) 1.
Fatehi-Hassanabad Z, Furman B L and Parratt JR (1996). Endothelium and ischaemic
preconditioning in rat isolated perfused heart J. Physiol. 494 112P.
KASZALA K, VEGH A, PAPP J Gy and PARRATT JR (1996) The role of bradykinin in
pacing-induced preconditioning. J Mol Cell Cardiol 28, A90.
KIS A, VEGH A, PAPP Gjy and PARRATT JR (1996) Repeated pacing widens the time
window of delayed protection against ventricular arrhythmias in dogs. J Mol Cell Cardiol 28,
A229.
NAGY S, KASZAKI J, WOLFORD A and PARRATT JR (1996) Effect of inhibition of
nitric oxide synthase on myocardial contractility and cardiac output in hyperdyanamic
endotoxaemia. Shock P28.
OSTADAL B, OSTADALOVA I, KOLAR F and PARRATT JR (1996) Tolerance to
ischaemia and ischemic preconditioning in neonatal rat hearts. J Mol Cell Cardiol 28, A126.
OSTADAL B, OSTADALOVA I, KOLAR F and PARRATT JR (1996) Ischaemic
preconditioning and myocardial contractile function in neonatal rat heart. J Mol Cell Cardiol
28, A302.
OSTADALOVA I, KOLAR F, OSTADAL B and PARRATT JR (1996)
preconditioning in neonatal rat hearts. J Physiol 491, 6P.
Ischaemic
PARRATT JR (1996) Myocardial contractility and cardioprotection: importance of
endothelium-derived nitric oxide. Alfred Benzon Symposium.
PARRATT JR (1996) Nitric oxide in the cardiovascular derangements of sepsis and
endotoxaemia. Shock 4, S-1.
PARRATT JR, VEGH A, PAPP J GY (1996) Aspects of the mechanisms of the
antiarrhythmic effects of ischaemic preconditioning. J Mol Cell Cardiol 28, A344.
Ravingerova T, Wu S, Pancza D, Ziegelhoffer A and Parratt JR (1996). Pre-conditioning
with catecholamines can suppress severe ventricular arrhythmias in the rat heart in vitro and
in vivo. Eur Heart J, 17 (suppl) abstract 609.
TAKESHIMA S, VALEN G, AHMAD M, ZIETLIN J, PARRATT JR and VAAGE J (1996)
Bradykinin is not released from the cardioplegic reperfused human heart. J Mol Cell Cardiol
28, A178.
VEGH A, PAPP Jgy, ELLIOT GT and PARRATT JR (1996) Pretreatment with
monophosphoryl lipid C (MPL-C) reduces ischaemia-reperfusion-induced arrhythmias in
dogs. J Mol Cell Cardiol 28, A217.
VEGH A, PAPP J GY and PARRATT JR (1996) Preconditioning against arrhythmias early
and delayed protection. J Mol Cell Cardiol 28, A344.
OSTADAL B, KOLAR K, OSTADALOVA I, PELOUCH V and PARRATT JR (1997)
Protection of the developing heart. J Mol Cell Cardiol 29, A9 (S29)
PARRATT JR, VEGH A, PAPP J GY and FATEHI-HASSANABAD Z (1997) Endothelial
myocyte interactions in cardioprotection. J Mol Cell Cardiol 29, A9 (S31)
RAVINGEROVA T, BARANCIK M, SONG W, PANCZA D, ZBYNOVCOVA M and
PARRATT JR (1997) Preconditioning with norepinephrine can induce acute and delayed
protection against arrhythmias in isolated rat heart. J Mol Cell Cardiol 29, A11 (S37).
VEGH A, KIS A, PAPP J GY and PARRATT JR (1997) Early and delayed protection
against arrhythmias. J Mol Cell Cardiol 29, A13 (S45).
RASTIGAR AM, VEGH A, PAPP J GY and PARRATT JR (1997) Can the already
preconditioned myocardium be additionally protected by preconditioning ‘At a distance’. J
Mol Cell Cardiol 29, A121 (Sa59)
KIS A, VEGH A, PAPP J GY and PARRATT JR (1997) Repeated pacing markedly prolongs
the delayed antiarrhythmic protection in anaesthetised dogs. J Mol Cell Cardiol 29, A122,
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VEGH A, SILELY M, PAPP J GY, SEMERARO C, POCCHIARI F, MORAZZONI G,
MARCHINI F and PARRATT JR (1997) The dopamine agonist Z1046 suppresses
ischaemia-induced ventricular arrhythmias in anaesthetised dogs. J Mol Cell Cardiol 29,
A122 (Sa63).
VEGH A, FATEHI-HASSANABAD Z, PAPP J GY, SEMERARO C, MARCHINI F and
PARRATT JR (1997) The antiarrhythmic effects of Z1046 are attenuated by domperidone:
evidence for the involvement of dopamine DA2 receptors. J Mol Cell Cardiol 29, A123
(Sa64).
VEGH A, PAPP J GY and PARRATT JR (1997) Preconditioning following manipulation of
the heart during coronary sinus catheterisation? J Mol Cell Cardiol 29, A123 (Sa65).
PARRATT JR, VEGH A and PAPP J GY (1997) Delayed cardiorprotection. Journal fur
Kardiologie 2, P29
GYORGY K, VEGH A, PAPP J GY and PARRATT JR (1997) Opening of KATP channel
with L-cromakalim before an ischaemic episode does not modify the severity of ischaemia
reperfusion-induced ventricular arrhythmias. Journal fur Kardiologie 2, P83
KIS A, VEGH A, PAPP G JY and PARRATT JR (1997) Repeated pacing widens the time
window of delayed antiarrhythmic protection in canine. Journal fur Kardiologie 2, P83
PARRATT JR, VEGH A, GYORGYI K and PAPP J Gy (1997) Cardioprotection by
bacterial endotoxin and by a monophosphoryl derivative of lipid A. Shock 8, Suppl abstract
149.