Download Yi-Ming A. Chen MD, MS, Sc.D.

Professor Yi-Ming Arthur Chen
Yi-Ming A. Chen M.D., M.S., Sc.D.
Distinguished Professor, Institute of Microbiology and Immunology
National Yang-Ming University （NYMU）
Taiwan
Email: [email protected]
Current Positions
Dean
Director
Director
Director
Joint appointment
Professor
Research member
Office of Research and Development, NYMU
Incubation Cener, NYMU
AIDS Prevention and Research Center, NYMU
International Health Program, NYMU
Institute of Brain Research, NYMU
Institute of Clinical Medicine, NYMU
Vaccine Research and Development Center
National Health Research Institute
Taiwan
Committees services in the campus:
Member: Biosafety Level 3 lab committee (2004 till mow)
Member: Sonogram committee (2009-2011)
1
Chairman: Ethical committee (2009-2011)
Education
1975-82 M.D., Department of Medicine, National Yang-Ming Medical College,
Taiwan
1982-84 M.S., Institute of Microbiology and Immunology, NYMU, Taiwan
1986-90 Sc.D., Department of Cancer Biology (Infectious Disease and Immunity),
Harvard School of Public Health, Boston, MA, USA
Working experiences
1982-1984
Teaching Assistant, Department of Microbiology and Immunology,
1984-1986
1986
NYMU, Taiwan
Aviation Doctor, Air-force General Hospital, (Military services), Taiwan
Lecturer, Department of Microbiology and Immunology, NYMU
1990-1992
Visiting Scientist, Lab of Molecular Oncology, National Cancer Institute,
USA
1992-1998
1992-1994
1998-2007
Associate Professor, Institute of Public Health, NYMU, Taiwan
Associate Research Member, Institute of Biomedical Sciences, Academia
Sinica, Taiwan
Professor, Institute of Public Health, NYMU, Taiwan
2002-2003
Visiting Scientist, HIV Drug Resistance Program, NCI, USA
2007-2009
Professor, Department of Microbiology and Immunology, NYMU
2009-2014
Distinguished Professor, Department of Microbiology and Immunology,
NYMU
2007-2010
Dean, Office of International Affairs
Advisory/steering committee and society
1992-2004 Member, AIDS Advisory Committee, Centers of Disease Control, Ministry
2004-2009
1994-2009
1993-2009
1996-2006
1996-2009
of Health, Taiwan
Member, Committee for AIDS Prevention and HIV-infected People’s
Rights Protection, Executive Yuan, Taiwan
Founder and Coordinator, Living with Hope Organization
Board Member, Taiwan Society of Preventive Medicine (has been elected
as secretary general in 1993-1996, as chairman in 1997-2003)
Advisory Board on Health Issues, Consumer Foundation, Taiwan
Board member, Taiwan AIDS Hope Association (Founder)
2
1998-2006
Council of Representative, Asia Pacific AIDS Services Organization
2001-2009
2001-2003
2002-2005
2008-2010
2001
2005-2007
2006-2009
Member, AIDS Education Advisory Committee, Ministry of Health,
Taiwan
Member, Steering committee, Therapeutic Research, Education and AIDS
Training in Asia (TREAT Asia) (has been elected as the chair since 2008)
Regional Task Force on HIV/AIDS Care and support in Asia
Vice Chairman, Global Chinese AIDS Network (co-founder)
Vice Chairman, Global Chinese AIDS Network
Medical Advisory Board, OmniViral Therapeutics LLC
Chairman, Taiwan AIDS Quilt Association (Founder)
Board member, Harmony Home Association （co-founder）
2003-2009
2007-2010
2006-2009
Board member, Taiwan Society of Epidemiology
Chairman, Taiwan Harm Reduction Association （台灣減害協會）
Consultant, Centers for Disease Control, Taiwan
2004-2009
2007-2009
2007-2009
2008-2009
2008-2010
2008-2009
depression)
2008-2009
2009
Consultant, Anti-drug Usage association, Tao-Yuan Prefecture, Taiwan
（桃園縣毒品危害防制委員會）
Consultant, Taipei City Government
Board Member, Taiwan Society of Microbiology
Managing Supervisor, Taiwan Society of Preventive Medicine
Board Member, Taiwan Can Love Association (for patients suffering
（Co-founder）
TREAT Asia Steering Committee Chair
Committee Member, Global Vaccine Access Council (University of
Western Ontario, Canada)
Member of the following societies: International Liver Cancer Association (member
#100708), American Association for Cancer Research (AACR) (member #52595),
American Society of Microbiology and Immunology, American Society of Human
Genetics, International AIDS Society (ID number 32042), Taiwan Society of
Epidemiology, Taiwan Society of Preventive Medicine, Taiwan Society of Microbiology,
Society of Public Health of ROC, Society of Cancer of ROC, Chinese Medical
Association.
Honors and awards
1. Scholarship from Society of Microbiology of ROC, Yen Shi-Chung Award, 1983.
3
2. Scholarship from the Ministry of Education to study abroad, Taiwan, R.O.C.,
3.
4.
5.
6.
7.
1986-89.
Scholarship from the Fogarty International Center, National Institutes of Health,
Program of International Training Grants 1989-92.
Education and Culture Award, Significant Contribution to the Scientific Education
for the Public, from the Ministry of Education, Taiwan, 1993.
Research award, from the National Science Council, Taiwan, 1993, 1994, 1995, 1997,
1999 and 2000.
Secretary General, the First, Second and Third Taipei International AIDS
Conferences, 1990, 1992 and 1994.
Candidate for the International Prince Mahidol Award from Thailand, nominated by
the Department of Health, Executive Yuan, R.O.C., 1994.
8. Young Investigator Award, First Joint Annual Conference of the Society of Oncology,
Taiwan, 1996.
Who’s Who in the World, 2001- 18th edition.
Who’s Who in Medicine and Healthcare, 2002 edition.
Who’s Who among Executives and Professionals, 2010 edition.
Scholarships from the National Science of Council of ROC for short-term training
(2003).
13. Outstanding Research Award from National Science Council, 2008.
14. Outstanding alumnus, Fu-Xin Primary school, 2004.
9.
10.
11.
12.
15. Invited as a reviewer for the following grant applications: National Science Council
(committee members on the Public Health and Environmental Sciences), University
Grants of Hong Kong, Specific Region of China and Pfizer AIDS foundation.
16. Best Paper Award from the Urbani Foundation 2005 and 2007.
17. Award to Special contribution to harm reduction program, 2007 from Ministry of
Health.
18. The Second Best Research Paper Award of the Chinese Medical Association Annual
meeting, 2007.
19. The Best Research Paper Award of the Taipei City Hospital grants, 2007.
20. Outstanding alumnus (Academic achievement), National Yang-Ming University,
2009.
21. Associate Editor, BMJ-Infectious Disease (since 2008); BMJ-Research Note (since
2008).
18. Editorial board member: Chinese Journal of Medicine, The OpenHepatologyJournal
(since 2008), Newsletter for Research on Applied Ethics (since 2000, in Chinese),
Liver Cancer Review Letters (since 2009), World Journal Hepatology (2009-2013).
19. Ad hoc referee for the following journals, institutions and conference organizers:
4
Hepatology,
Lancet
AIDS Research and Human Retroviruses,
Blood
Journal of Hepatology
Journal of infectious Disease
American Journal of Pathology
Experimental Biology and Medicine
Taiwan J. Public Health
Jouranl of Chinese Society of Physiology
Acta Pharmacol Sin
Infection Genetic and Evolution
Retrovirology
International Journal of Drug Policy
Environmental Health Perspectives
the XIII, XIV, XV and XVI International AIDS Conferences;
the 6th and 7th International Conference on AIDS in Asia and Pacific (ICAAP);
the 4th IAS meeting
National Medical Research Council of Singapore
Hong Kong Department of Health
Welcome Trust
Chief Scientist Office, UK
5
Publication List
Referred papers: (*corresponding author)
1. Chen YM, Hu CP, Wong FH, et al. Circulating immune complexes in the sera and
ascites of hepatocellular carcinoma patients. Chinese J. Micro. Immunol. 19:34-45,
1986.
2. Chen YM, Hu C, Chen P, et al. Nuclear antigens reacted with sera and ascites of
hepatocellular carcinoma patients. Hepatology 8:547-552, 1988.
3. Matsuda Z, Chou MJ, Matsuda M, Huang JH, Chen YM, Redfield R, Mayer K, Essex
M and Lee TH. Human immunodeficiency virus type 1 has an additional coding
sequence in the central region of the genome. Proc. Natl. Acad. Sci., USA 85:
4.
5.
6.
7.
6968-6972, 1988.
Chen YM, Lee TH, Samuel KP, Okayama A, Tachibana N, Miyoshi I, Papas TS, and
Essex M. Antibody reactivity to different regions of human T-cell leukemia virus
type-I (HTLV-I) gp61 in infected people. J Virol 63: 4952-4957, 1989.
Chen YM, Lee TH, Wiktor SZ, Shaw GM, Murphy EL, Blattner WA and Essex M.
Type-specific antigens for serological discrimination of HTLV-I and II infection.
Lancet 336: 1153-1155, 1990.
Chen YM, Gomez-Lucia E, Okayama A, Tachibana N, Lee TH, Mueller N and Essex
M. The antibody profile of early HTLV-I infection. Lancet 336: 1214-1216, 1990.
Okayama A, Chen YM, Tachibana N, Shioiri S, Lee TH, Tsuda K and Essex M.
High incidence of antibodies to HTLV-I tax in blood relatives of adult T-cell
leukemia patients. J. Infect. Dis. 163: 47-52, 1991.
8. Chen YM, Okayama A, Lee TH, Tachibana N, Mueller N and Essex M. Sexual
transmission of HTLV-I associated with the presence of the anti-tax antibody. Proc.
Natl. Acad. Sci. USA 88: 1182-1186, 1991.
9. Chen YM and Essex M. Identification of a recombinant HTLV-II envelope protein
with distinguishing reactivities to sera from HTLV-II carriers. AIDS Res. Hum.
Retroviruses 7: 453-457,1991.
10. Chen YM, Zhang X-q, Dahl C, Samuel KP, Schooley RT, Essex M and Papas TS.
Delineation of type-specific regions on human T-cell leukemia virus envelope
glycoproteins. J. Immunol. 147: 2368-2376, 1991.
11. Chen YM*. Serological discrimination of HTLV-I and HTLV-II infection by
recombinant protein-western blot assays. Biomed. Pharmacotheraphy 45:274, 1991.
12. Okayama A, Kober B, Chen YM, Allan J, Lee TH, Shioiri S, Tachibana N, Tsuda K,
Mueller N, Mclane MF, Maayan S, Markink R, Orgad S and Essex M. Unusual
pattern of antibodies to HTLV-I in family members of adult T-cell leukemia patients.
Blood 78: 3323-3329, 1991.
6
13. Samuel KP, Hodge DR, Chen YM and Papas TS. Nef protein of the human
immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus
(SIV) are structurally similar to leucine zipper transcriptional activation factors.
AIDS Res. Hum. Retroviruses 7: 697-706, 1991.
14. Zhang X-q, Yang L, Ho DD, Kuritzkes D, Chen I, Chen YM and Schooley RT.
HTLV-I and HTLV-II Specific antibody dependent cellular cytotoxicity: strain
specificity and epitope mapping. J. Infect. Dis. 165: 805-812, 1992.
15. Maayan S, Dan M, Marlink R and Chen YM*. Exposure to Human Retroviruses
HTLV-I, HTLV-II and HIV among Israeli IV drug abusers. Int. J. Epidemio.
21:995-997, 1992.
16. Whang-Peng J, Chen YM, Knutsen T, Zhao W-P and Tsai S. Chromosome studies in
HTLV-I, II, and HIV-1, 2 cell lines infected in vivo and in vitro. JAIDS J. Acqui.
Immun. Defic. Syndr. 6: 930-940, 1993.
17. Chen YM*, Jang Y-J, Kanki PJ, Wang J-J, Montali RJ, Samuel KP and Papas TS.
Isolation and characterization of simian T-cell leukemia virus type II from New
World monkeys. J. Virol. 68: 1149-1157, 1994.
18. Hodge DR, Chen YM and Samuel KP. Oligomeraization of the HIV-2 Nef Protein:
mutational analysis of the heptad leucine repeat motif and cysteine residues. AIDS
Res. Hum. Retroviruses 11: 65-79, 1995.
19. Chen YM. Taiwan's sex-workers have less than 1% infection. AIDS Analysis Asia 1:
2 1995.
20. Chang L-J, Chen YM, Chen, M-Y, Chou C-C, Twu SJ, Huang L-M. HIV 10 years
later-where do we stand now? J Biomed Sci 2: 1-11, 1995.
21. Yao C, Wang W-W, Chung Y-M, Su Y-L, Liu C-Y and Chen YM*.
Transfusion-acquired AIDS in Taiwan. J. Formos. Med. Assoc. 95: 51-55, 1996.
22. Chen YM*, Lin H-C and Chou P. A population-based epidemiological study of
human T-cell leukemia virus type I infection in Kin-Hu, Kinmen. Int. J. Cancer 59:
569-573, 1996.
23. Yao C, Kao S-S, and Chen YM*. Cost-benefit analyses of the HIV-1 and
HIV-1/HIV-2 screening program in blood donation centers in Taiwan. Chin. J. Public
Health (Taipei), 15: 483-496, 1996.
24. Chang P, Liau M-Y, Yang C-M, Ho M-S, Lee C-H, Chen YM and Horng C-B. Cost
analysis of establishing the capability of producing MMR, DTaP, HBV, and OPV
vaccines in Taiwan. Chin. J. Public Health (Taipei), 15: 517-524, 1996.
25. Chen YM*, Chang L-Y, Fu C-Y and Chou P. A survey of knowledge, attitudes and
practices (KAP) concerning AIDS among female sex workers from massage parlors
in Taiwan. Chin. J. Public Health (Taipei), 16: 439-454, 1997.
7
26. Shieh B, Lee C-M, Su I-J, Chen YM and Li C. Molecular subtyping of the V3 loop
sequences detected in HIV-1-positive patients at the National Cheng Kung University
Hospital. Chinese J. Micro. Immunol. 30: 46-54, 1997.
27. Li C, Yan Y-P, Shieh B, Lee C-M, Lin R-Y, and Chen YM*. Analysis of the CKR5
allele in AIDS patients and female sex workers in Taiwan. J. Formos. Med. Assoc. 96:
979-984, 1997.
28. Chen YM*, Chen S-H, Chen J-Y and Osame M. Antibody reactivities to
tumor-suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected
people with differing clinical status. Int. J. Cancer 71:196-202, 1997.
29. Chen Y-J, Shih L-S, Chang J-G, Whang-Peng J, and Chen YM*. Frequent detection
of aberrant RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma.
Int. J. Cancer 71: 350-354, 1997.
30. Chen YM*, Yu PS, Lin C-C and Jen I. Surveys of HIV-1 HTLV-I and other sexually
transmitted diseases among female sex workers in Taipei city and prefectures, Taiwan
from 1993 to 1996. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 18:
299-303, 1998.
31. Chen YM*, Lee C-M, Lin R-Y, Chang H-J. Molecular epidemiology and Trends of
HIV-1 Subtypes in Taiwan. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol.
19: 393-402, 1998.
32. Chen YM*, Shiu J-Y, Tzeng SJ, Li-Sun Shih, Yi-Jen Chen and Lui W-Y.
Characterization of the glycine-N-methyltransferase-gene expression in human
hepatocellular carcinoma. Int. J. Cancer 75: 787-793, 1998.
33. Chen Y-J, Shih L-S and Chen YM*. Quantitative analysis of CDKN2, p53 and
retinoblastoma mRNA in human gastric carcinoma. Int J Oncol 13: 249-254, 1998.
34. Chen YM*, Lin R-H, Lee C-M, Fu C-Y, Chen S-C and Syu W-J. Decreasing levels
of anti-Nef antibody correlate with increasing viral loads and AIDS disease
progression. AIDS Res. Human Retroviruses 15: 43-50, 1999.
35. Chen YM*, Ting S-T, Lee C-M, W-T Liu, Pan W-H, TA Chang, Chou P.
Community-based molecular epidemiology of human T-cell leukemia virus type I
infection in Taiwan and Kinmen: Implication of the origin of the cosmopolitan
subtype in North East Asia. AIDS Res Human Retroviruses 15: 229-237, 1999.
36. Liou YM, Chou P, Chen YM*. Genotypic Analysis of HCV infection in Kinmen. J.
Microbiol. Immunol. Infect. 33: 63-68, 2000.
37. Chen YM*, Chen LY, Wong FH, Lee CM, Chang TJ, Yang-Feng TL. Genomic
structure, expression and chromosomal localization of the human glycine
N-methyltransferase gene. Genomics 66: 43-47, 2000.
38. Chen YM*, Huang KL, Jen I, Chen SC, Liu YC, Chuang YC, Wong JC, Tsai JJ.
Temporal trends and molecular epidemiology of HIV-1 Subtypes in Taiwan from
8
1988 to 1998. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 26: 274-282,
39.
40.
41.
42.
2001.
Chen YM*, Rey WY, Lan YC, Lai SF, Huang YC, Wu SI, Liu TT, Hsiao KJ.
Antibody reactivity to HIV-1 Vpu in HIV-1/AIDS patients on highly active
antiretroviral therapy. J. Biomed. Sci. 10: 266-275, 2003.
Yang MH, Chen YM, Kuo BI, Wang KY. Quality of life and related factors for
people living with HIV/AIDS in Northern Taiwan. J. Nurs. Res. 11: 217-26, 2003.
Liu HH, Chen KH, Shih YP, Lui WY, Wong FH, Chen YM*. Characterization of
reduced expression of glycine N-methyltransferase in the cancerous hepatic tissues
using two newly developed monoclonal antibodies. J. Biomed. Sci. 10: 87-97, 2003.
Tseng TL, Shih YP, Huang YC, Wang CK, Chen PH, Chang JG, Yeh KT, Chen
YM*, Buetow K. Genotypic and phenotypic characterization of a putative tumor
susceptibility gene, GNMT, in liver cancer. Cancer Res. 63: 647-654, 2003.
43. Chen SY, Lin JR, Darbha R, Liu TY, Lin CH, Chen YM*. Glycine
N-Methyltransferase tumor susceptibility gene in the Benzo(a)pyrene-detoxification
pathway. Cancer Res. 64: 3617-3623, 2004.
44. Lan YC, Liu HF, Shih YP, Yang JY, Chen HY, Chen YM*. Phylogenetic analysis
and sequence comparisons of structural and non-structural SARS coronavirus
proteins in Taiwan. Infect. Genetic. Evolu. 5: 261-269, 2005.
45. Lan YC, Liu TT, Yang JY, Chen YJ, Lu JJ, Chan YJ, Liu HF, Chen HY, Suing CA,
Hsiao KJ, Ho MS, Chen YM*. Molecular epidemiology of SARS coronavirus
infection in Taiwan. J. Infect. Dis. 191: 1478-1489, 2005.
46. Huang CY, Sun CT, Hsieh JL, Chen YM, Lin H. A novel small-world model: using
social mirror identities for epidemic simulations. Simulation 81: 671-699, 2005.
47. Zhou J, Kumarasamy N, Zhang F, Zhao H, Han N, Li P, Lee MP, Chen YM, Wong
WW, Wang DCC, Anand S, Cecelia JA, Pujari S, Joshi K, Lee CKC, Kaur S,
Kamarulzaman A, Ditangco R, Capistrano R, Paton NI, Yap M, Phanuphak P,
Siangphe U, Khongphattanayothing M, Vibhagool A, Kiertiburanakul S, Kiatatchasai
W, Chuah J, Fankhauser W, Dickson B, Frost K, Wong S, Cooper DA, Law MG,
Petoumenos K. Predicting short-term disease progression among HIV-infected
patients in Asia and the Pacific region: Preliminary results from the TREAT Asia
HIV Observational Database (TAHOD)HIV Med 6: 216-223, 2005.
48. Chen WJ, Yang JY, Lin JH, Fann CSJ, Osyetrov V, King CC. Chen YM, H. L.
Chang HL, Kuo HW, F. Liao F, Ho MS. Nasopharyngeal shedding of severe acute
respiratory syndrome-associated coronavirus is associated with genetic
polymorphisms.Clin. Infect. Dis.42: 1561-1569, 2006.
49. Chen, YM*, Liang SY, Chu DC, Lee YM, Chang L, Jung SY, Chen HY, Chjan YJ,
Ho MS, Liang KY, Jang Y-J, Chu T-C. Epidemiological and genetic correlates of
9
SARS coronavirus infection in a hospital with the highest nosocomial infection rate
50.
51.
52.
53.
in Taiwan in 2003. J. Clinc. Microbio. 44: 359-365, 2006.
Hsieh YH, Lee SM, Chen CW-S, Chen YM, Wu S-I, Lai SF. Estimating the
HIV-1-infected population size within hard-to-count MSM groups: the case of gay
saunas patrons in Taipei area. Physica A 362: 495-503, 2006.
Chen YM*, Lan YC, Lai SF, Yang JY, Tsai SF, Kuo HS. HIV-1 CRF07_BC
infections, injecting drug users, Taiwan. Emerg. Infect. Dis. 12: 703-705, 2006.
Lee CM, Chen SY, Lee YCG, Huang CYF, Chen YM*. Benzo[a]pyrene and glycine
N-methyltransferse interactions: Gene expression profiles of the liver detoxification
pathway. Toxicol. Appl. Pharmacol. 214: 126-135, 2006.
Chiu HC, Wang FD, Chen YM, Wang CT. Effects of human immunodeficiency virus
type 1 transframe protein p6* mutations on viral protease-mediated Gag processing. J.
Gen. Virol. 87: 2041-2046, 2006.
54. Qiu JT, Chang TC, Lin CT, Chen YM, Li F, Soong YK, Lai CH. Novel
codon-optimized GM-CSF gene as an adjuvant to enhance the immunity of a DNA
vaccine against HIV-1 Gag. Vaccine Vaccine. 2006 Aug 4; [Epub ahead of print].
55. Shih YP, Chen CY, Liu SJ, Chen KH, Lee YM, Chao YC, Chen YM.* Identification
of the Epitopes Responsible for Neutralizing Antibody and DC-SIGN Binding on the
Spike Glycoprotein of the Severe Acute Respiratory Syndrome Coronavirus. J. Virol.
80: 10315-10324, 2006.
56. Hsu CH, Hwang KC, Chao CL, Chang SGN, Ker CC, Chien LC, Ho MS, Lin JG,
Chen YM, Chou P. The lesson of supplementary treatment with Chinese medicine on
severe laboratory-confirmed SARS patients. Am. J. Chin. Med. 34: 6927-6935, 2006.
57. Zhou J, Paton NI, Ditangco R, Chen YM, A Kamarulzaman, N Kumarasamy, CKC
Lee, PCK Li, TP Merati, P Phanuphak, S Pujari, A Vibhagool, F Zhang, J Chuah, KR
Frost, DA Cooper and MG Law. Experience with the use of a first-line regimen of
stavudine, lamivudine and nevirapine in patients in the TREAT Asia HIV
Observational Database. HIV Med. 8: 8-16, 2007.
58. Coulibaly S, Yen PMN, Fu LA, Chen YM*. Needs assessment of people living with
HIV/AIDS in Taiwan. Taiwan J. Public Health 26: 38-48, 2007.
59. Huang YC, Lee CM, Shih YP, Chung MY, Chang YH, Huang JSW, Ho MTD, Pan
CC, Wu TL, Hsu JM, Yang S, Lin MW, Chen YM.* Characterization of the
haplotypes, loss of heterozygosity and expression levels of glycine
N-methyltransferase gene in prostate cancer. Clin. Cancer Res. 13: 1412-1420, 2007.
60. Chen YM* and Kuo HS. HIV-1 in Taiwan. Lancet 369: 623-625, 2007. (has been
chosen as the Article of the Month, April 2007 by the International Harm Reduction
Association).
10
61. Lin YT, Lan YC, Chen YJ, Liu TT, Yang JY, Wong WW, Wang CT, Chen YM.*
Molecular epidemiology and full-length genomic analysis of HIV-1 circulating
recombinant form 07_BC strains from injecting drug users in Taiwan. J. Infect. Dis.
195: 1283-1293, 2007.
62. Huang YC, Chung MY, Chang YH, Huang JSW, Wu TL, Hsu JM, Yang S, Lin MW,
Chen YM.* The CYP19 tri-nucleotide Del/Del genotype is a susceptibility marker for
prostate cancer in a Chinese population. Urology 69: 996-1000, 2007.
63. Lien SP, Shih YP, Lien S, Tsai JP, Leng CH, Chen HW, Lin MH, Liu SY, Chen YM,
Chong P, Liu SJ. Identification of synthetic vaccine candidates against SARS CoV
infection. Biochem. Biophys. Res. Commun. 358: 716-721, 2007.
64. Chen CY, Ping YH, Lee HC, Chen KH, Lee YM, Lian DC, Jap TS, Lin CH, Kao LS,
Chen YM.* ORF8a of the severe acute respiratory syndrome coronavirus not only
promotes viral replication but also induces apoptosis. J Inf Dis, 2007; 196: 405-415.
65. Zhou J, Dore GJ, Zhang F, Lim PL, Chen YM*. Hepatitis B and C virus coinfection
in the TREAT Asia HIV Observational Database. J Gastroent Hepatol, 2007; 22:
1510-1518.
66. Medah I, Lai SF, Chuang SY, Chang CL, Yen PMN, Chen YM*. Knowledge,
attitude, and practices towards human immunodeficiency virus type 1 infection
among new entrant university students in Taiwan. Taiwan J Public Health 2007; 26:
324-337.
67. Liu SP, Li YS, Chen YJ, Chiang EP, Li AFY, Lee YH, Tsai TF, Hsiao M, Huang CF,
Chen YM.* Glycine N-methyltransferase-/- mice develop chronic hepatitis and
glycogen storage disease in liver. Hepatology 2007; 46: 1413-1425.
68. Goka EAC, Yen PMN, Chiou JQ, Lin CL, Wu CM, Fan HH, Chen YM*. Knowledge
attitudes and practice of antenatal mothers on HIV/AIDS and their satisfaction with
PMTCT program in Taiwan. Int. J. Coop. 2007; 2: 65-88.
69. Lan YC, Elbeik T, Dileanis J, Ng V, Chen YJ, Leu HS, Cheng SH, Wong JC, Wong
WW, Chen YM*. Molecular epidemiology of HIV-1 subtypes and drug resistant
strains in Taiwan. J. Med. Virol. 2008; 80: 183-191.
70. Huang YC, Chen M, Li AFY, Su CH, Shyr YM, Ho DMT, Chen YM*. Glycine
N-methyltransferase is a favorable marker for human cholangiocarcinoma. J.
Gastroenterol. Hepatol. 2008; 23:1384-1389. Epub 2008 Jul 8.
71. Wang SF, Huang JC, Lee YM, Liu SJ, Chan YJ, Chau YP, Chuang P, Chen YM*.
DC-SIGN mediates avian H5N1 influenza virus infection in cis and in trans. Biochem.
Biophys. Res. Commun. 2008 373: 561-566. Epub 2008 Jun 30.
72. Chuang PC, Liu H, Sola C, Chen YM, Jou R. Spoligotypes of mycobacterium
tuberculosis isolates of a high tuberculosis burden aboriginal township in Taiwan.
Infect. Genet. Evol. 2008; 8: 553-557.
11
73. Liao, YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY; Tsai TF; Huang SF,
Lee-Wu Yan-Hwa, Chen YM*. Characterization of a glycine N-methyltransferase
gene knockout mouse model for hepatocellular carcinoma. Int. J. Cancer, 2009; 124:
816-826. (epublication Sep 2008).
74. Yen CH, Hung JH, Liu SP, Chen SY, Chou TY, Tsai TF, Darbha R, Hsieh LL, Chen
YM*. Glycine N-Methyltransferase Interacts with Aflatoxin B1 and Blocks its
Carcinogenic Effect. Toxicol. Appl. Pharmacol. 2009; 235: 296-304 (epublication
December 2008).
75. Wang SF, Chen KH, Thitithanyanont A, Yao L, Lee YM, Chan YJ, Liu SJ, Chong P,
Liu WT, Huang JC, Chen YM.* Generating and Characterizing Monoclonal and
Polyclonal Antibodies against Avian H5N1 Hemagglutinin Protein. Biochem.
Biophys. Res. Commun. 2009; 15: 382: 691-696.
76. Lee CM, Shih YP, Chen YM*. Characterization of the 5' Regulatory Region of the
Human Glycine N-methyltransferase Gene. Gene, 2009 15; 443: 151-157.
77. Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang W J-S, Yi-Ming Arthur Chen
YM*. The rs1447295 at 8q24 is a risk variant for prostate cancer in Taiwanese men.
Urology 2009 May 8. [Epub ahead of print]
78. Wang SF, Huang JC, Lee YM, Liu SJ, Chan YJ, Chau YP, Chuang P, Chen YM*.
Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics
of the hemagglutinin gene. J. Med. Virol. 2009; 81: 1457-1470.
79. Zhou J, Elliott J, Li PCK, Lim PL, Kiertiburanakul S, Kumarasamy N, Merati TP,
PUjari S, Chen YM, Phanuphak P, Vonthanak S, Sirisanthana T, Sungkanuparph S,
Lee CKC, Kamarulzaman A, Oka S, Zhang F, Tau G Ditangco R. Risk and
prognostic significance of tuberculosis in patients from The TREAT Asia HIV
Observational Database. BMC Infect Dis 2009; 9: 46-55.
80. Srasuebkul P, Lim PL, Lee MP, Kumarasamy N , Zhou J, Saphonn V, Zhang FJ, Li
PCK, Pujari S, Merati TP, Oka S, Choi JY, Lee C KC, Kamarulzaman A, Tau G,
Ditangco R, Chen YM, Phanuphak P, Sungkanuparph S, Sirianthana T, Smith J and
Law M G. Short-term clinical disease progression in HIV-1-positive patients taking
combination antiretroviral therapy: TAHOD results. Clin. Inf. Dis. 2009; 48:
940-950.
81. Peng EYC, Lee MB, Morisky DE, Yeh CY, Farabee D, Lan YC, Chen YM, Lyu SY*.
Psychiatric morbidity in HIV-infected male prisoners. J Formos Med Asso, in press,
2009.
82. Tsai MC, Chen YM, H Cheng. Enhanced Expression of Glycine N-Methyltransferase
by Adenovirus-Mediated Gene Transfer in Mixed Neuronal Culture is
Neuroprotective. Annals of the New York Academy of Sciences. in press, 2009.
12
83. Land S, Cunningham P, Frost K, Katzenstein D, Kantor R, Chen YM, Oka S,
84.
85.
86.
87.
DeLong A, Sayer D, Smith J, Dax EM, Law M. The TREAT Asia quality assessment
scheme to standardize the outcome of HIV genotypic resistance testing in a group of
Asian laboratories. J Virol Meths 2009; 159: 185-193.
Chen YM*, Liao YJ, Liu SP, Tsai TF. Phenotypic difference of two GNMT-/- mouse
model for hepatocellular carcinoma. Hepatology, 2009; 49: 2130-2131.
Lee YM, Wang SF, Chan YJ, Chen YM*. 2006-2007 Outbreak of reassortant
influenza B virus in north Taiwan. BMJ Res Note, 2009; 2: 85-96.
Chen YM*, Yen CH, Liu SP, Liao YJ. Response to the letter to the editor from Dr.
Conrad Wagner. Toxicol. Appl. Pharmacol. 2009, in press.
Huang JC, Chang YF, Chen KH, Lee CW, Su LC, Chen CC, Chen YM*, Chou C*.
Detection of Severe Acute Respiratory Syndrome (SARS) Coronavirus Nucleocapsid
Protein in Human Serum using a Localized Surface Plasmon Coupled Fluorescence
Fiber-optic Biosensor. Biosensors and Bioelectronics, 2009, 25: 320-325.
88. Tsai PC, Fu TW, Chen YM, Ko TL, Chen TH, Shih YH, Hung SC, Fu YS. The
therapeutic potential of human umbilical mesenchymal stem cells from Wharton;s
jelly in the treatment of rat liver fibrosis. Liver Transplant, 2009; 15: 484-495.
89. Pujari S , Srasuebkul P, Sungkanuparph S, Lim PL, Kumarasamy N, Chuah J, Kumar
RN, Chen YM, Oka S, Choi JY, Lee MP, Phanuphak P, Kamarulzaman A, Lee C,
Fujie Z, Ditangco R, Saphonn V, Sirisanthana T, Parwati T, Merati, Smith J, Law
MG. Patient characteristics and treatment outcome associated with Protease Inhibitor
(PI) use in the Asia-Pacific region. J Antimicrobiol Chemother, 1: 28-35, 2009.
90. Lee YM, Lin HJ, Lee CM, Chen YJ, Chen YM* Molecular Epidemiology of HCV
Genotypes among Injection Drug Users in Taiwan: Full-length sequences of two new
subtype 6w strains and a recombinant form_2b6w. J Med Virol, 82: 57-68, 2010.
91. Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang W J-S, Yi-Ming Arthur Chen
YM*. Common variants at 8q24 are associated with prostate cancer risk in Taiwanese
men. Prostate, 70: 502-507, 2010. [2009 Nov 11. Epub ahead of print]
92. Chan YJ, Lee CL, Hwang SJ, Fung CP, Wang FD, Yen DHT, Tsai CH, Chen YMA,
Lee SD. Seroprevalence of antibodies to pandemic (H1N1) 2009 influenza virus
among hospital staff in a medical center in Taiwan. J Chin Med Assoc, 73: 62-66,
2010.
93. Liao YJ, Liu SP, Chen GT, Chen YM.* Deficiency of glycine N-methyltransferase
results in deterioration of cellular defense to stress in mouse liver. Proteomics-Clin
Applic, 4: 1-13, 2010. (Being selected as the feature story of the April issue, 2010)
94. Chen YJ, Huang YH, Kao DYT, Lan YC, Yang JY, Chen YM*. Molecular
epidemiology of subtype B, CRF01_AE and CRF07_BC Infection among Injection
Drug Users in Taiwan. J AIDS, 53: 425-439, 2010.
13
95. Oyomopito R, Lee MP, Phanuphak P, Lim PL, Citangco R, Zhou J, Sirianthana T,
Chen YM, Pujar S, Kumarasamy N, Sungkanuparph S, Lee CKC, Kumarulzaman A,
Oka S, Zhang FJ, Mean CV, Merati TP, Tau G, Li PCK. Measures of country and site
resourcing predict virologic suppression, immunologic response and HIV disease
progression following HAART in the TREAT Asia HIV Observational Database
(TAHOD). HIV Medicine, in press, 2010.
96. Liu SP, Li YS, Lee CM, Yen CH, Huang SF, Chien CH, Chen YM*. Susceptibility to
aflatoxin B1-related hepatocellular carcinoma in glycine N-Methyltransferase
knockout mice. Int J Cancer, in press, 2010. (epublication, April 2010)
97. Zhou J Pujari S , Srasuebkul P, Sungkanuparph S, Lim PL, Kumarasamy N, Chuah J,
Kumar RN, Chen YM, Oka S, Choi JY, Lee MP, Phanuphak P, Kamarulzaman A,
Lee C, Fujie Z, Ditangco R, Saphonn V, Sirisanthana T, Parwati T, Merati, Smith J,
Law MG. Deferred modification of antiretroviral regimen following documented
treatment failure in Asia: results from The TREAT Asia HIV Observational Database
(TAHOD) HIV Medicine, 2009, submitted.
98. Peng EY, Yeh CY, Lyu SY*, Morisky DE, Chen YM, Lee MB, Farabee D, Malow R.
Prevalence and correlates of lifetime suicidal ideation among HIV-infected male
inmates in Taiwan. AIDS Care, in press, 2010.
99. Chuang PC, Chen HY, Chen YM, Jou R. Single nucleotide polymorphisms of cell
wall biosynthesis associated genes and a phylogeny of principal genetic group 1
Mycobacterium tuberculosis complex. Infect Genet Evol, in press, 2010.
100. Lee CM, Huang YZ, Chang TY, Chen YM*. The androgen response element of
glycine N-methyltransferase gene is located in the first intron. Biochem J, in revision,
2010.
101. Cheng SH, Peng ETC, Yeh CY, Morisky DE, Lan YC, Chen YM, Lyu SY. A
case-control study of HIV infection among incarcerated female drug users: impact of
sharing needles and having drug-using sexual partners. BMC Infec Dis, submitted,
2009.
102. Tsai TI, Chen IJ, Morisky D, Chen YM*. Service modalities and attitudes as keys in
needle exchange programmes-a survey of service providers. J AIDS Pre Care, in
press, 2010.
103. Chiang SC, Chu FY, Cheng SH, Chen YM, Chen CK. Psychiatric comorbidity and
prevalence of HIV and hepatitis C virus among illicit drug abusers in Taiwan: a
cross-sectional study. BMC Res Note, submitted, 2009.
104. Chang YJ, Chen HC, Lee BH, You SL, Lin CY, Pan MH, Chou YC, Hsieh CY, Chen
YM, Cheng YJ, Chen CJ. Intratypic Variants of Human Papillomavirus Types 16, 18,
52 and 58 in Taiwan. Int J Cancer Submitted, 2009.
14
105. Fan APC, Kuo HCC, Kao DYT, Morisky DE, Chen YM*. Quality of Life and Needs
Assessment on People Living with HIV and AIDS in Malawi. 2010, AIDS Care, in
press.
106. Chen CC, Kruger J, Sramala I, Hsu HJ, Henklein P, Chen YM, Fischer WB. Open
Reading Frame 8a of SARS-CoV forms an ion channel: experiments and molecular
dynamics simulations. Submitted, Am J Chem, 2010.
107. Yang YC, Yeh CC, Wang RY, Ling MP, Lai JS, Chen KH, Lu CK, Lyu SY, Chen
YM, Lan YC. A predictive model for male injecting drug users at risk of contracting
HIV-1. BMC Public Health, submitted, 2010.
108. Fan A, Chen YM, Lee CC. Ethnic Minority Students Increase Diversity at no Cost to
Academic Competency. Med Edu, 2010, submitted.
109. Oyomopito R, Phanuphak P, Sungkanuparph S, Kumarasamy N, Sirisanthana T, Li P,
Kantipong P, Lee C, Kamarulzaman A, Chen YM. Cohort Profile: The TREAT Asia
Studies to Evaluate Resistance Monitoring Study (TASER-M) - HIV Drug Resistance
in the Asia-Pacific. Int J Epi, submitted, 2010.
110. Liao CF, Wang SF, Lin YT, Chen YM*. Identification of the DC-SIGN-interactive
domains on the envelop glycoprotein of HIV-1 CRF07_BC. J Virol, 2010, submitted.
111. Wang SF, Yao L, Liu SJ,, Chong P, Chen YM*, Huang JC*.. Identifying
DR1501-restricted CD4+ T cell Epitopes in Hemagglutinin Proteins after H5N1
Vaccine Inoculation. Viral Immuno, revision, 2010.
112. Wang SF, Su MW, Yao L, Liu WT, Chu WC, Chen YM*, Huang JC*... Genetic
Characteristics and Receptor Binding Specificity of Hemagglutinin Proteins in the
Swine-Origin Influenza A (H1N1) Virus. Infec Gene Evolution, submitted, 2010.
113. Lin YT, Huang SW, Oka S, Kuritzkes DR, Hu Z, Giguel F, Liao CF, Chen YM*.
Biological characterization and drug susceptibilities of CRF07_BC strains from
treatment-naïve patients in Taiwan. In preparation, 2010.
114. Yang CP, Su NY, Tsai TH, Chen CJ, Hong CJ, Chen YM*. Behavioral
characterization of the glycine N-mehyltransferase knockout mice: potential roles of
GNMT in schizophrenia. In preparation, 2010.
115. Chen M, Ho CW, Huang YC, Pan CH, Wu KY, Chen CJ, Shih TS, Chen YM*.
Glycine N-methyltransferase may confer protection against environmental polycyclic
aromatic hydrocarbons in coke-oven workers. Cancer Prev Biomark, submitted, 2010.
116. Yen CH, Lu YC, Lee CM, Chen CY, Huang CH, Kao FJ, Chou TY, Wu Lee YH,
Chen YM*. DEPDC6 is a GNMT-binding protein frequently overexpressed in
hepatocellular carcinoma and associated with tumorigenesis. In preparation, 2010.
15
Patents
1.
2.
3.
4.
5.
United States Patent: Detection and Correction of Abnormalities of Cells having
Decreased Levels of Glycine N-methyltransferase. Patent number: 5994093
(Duration: Nov. 30, 1999-Nov. 30, 2019).
ROC Patent: Detection and Correction of Abnormalities of Cells having Decreased
Levels of Glycine N-methyltransferase. Patent number: 086114505 (Duration:
Oct. 4, 1997-Oct. 4, 2017).
United States Patent: Glycine N-methyltransferase monoclonal antibodies and
methods of use therefore. Patent number: 7176291 (Duration: February 13,
2007-2027).
United States Patent: Glycine N- methyltransferase (GNMT) animal model and use
thereof. Patent number: to be determined (Duration: Aug. 1, 2007-2027).
A mouse model for depression, schizophrenia and Alzheimer’s disease. Under
review ((Patent application in five regions including US, Europe, mainland China,
Taiwan and Japan).
Book Chapters
1.
2.
3.
4.
5.
6.
Jeng KS, Hu CP, Lo SJ, Chen YM, Su TS, Ting LP, Chou C H, Hana SH, Salfeld J,
Pfaff E, Schaller H, Chang C. Production of hepatitis B virus by transfection of
cloned hepatitis B virus DNA in a hepatoma cell line. In: Viral Hepatitis and Liver
Disease. Alan R. Liss, Inc., 1988, pp. 355-359.
Chen YM, Essex M. Antibody responses to different regions of HTLV-1 gp61 in
asymptomatic carriers, ATL patients and individuals with TSP. In: Human
Retrovirology: HTLV (W. Blattner, Ed.). Raven Press, 1990, pp. 447-460.
Chen YM, Essex M. Immunogenicity of human retrovirus-specific proteins. In: Gene
Regulation and AIDS (T. S. Papas, Ed.). Gulf Publishing Co., Houston, 1990, pp.
239-245.
Chen YM, Sankale J-L. Chapter 4: Other human retroviruses. In Essex, M., Mboup,
S., Kanki, P. J. and Kalengayi, M. R. (eds.): AIDS in Africa. Raven Press, New York,
1994, pp. 67-95.
Horng C-B, Chen YM, Chang PL. Vaccine development in Taiwan. Proceedings of
the Asia-Pacific Conference on Health Care in the 21st Century. Taipei, Taiwan.
1994.
Chen YJ, Lee MD, Liu MH, Chen PH, Chen YM. The study of p16 (MTS1) gene
expression in gastric cancer cell lines and uncultured gastric cancers. In Nishi M,
Sugano H, and Takahashi T, (eds): Proceedings of the 1st International Gastric
Cancer Congress, Monduzzi Editore, Italy, pp. 713-717, 1995
16
7.
Chen YM. Preventive Medicine. (Writer and Editor). Chinese Society of Preventive
Medicine Press, 1996.
8. Chen YM, Lin R-H, Fu C-Y, Lin R-Y, Syu W-J. Decreasing levels of anti-Nef
antibody correlate with increasing viral loads in HIV-1 infected people with differing
clinical status. Proceedings of the 12th World AIDS Conference. Monduzzi Editore,
Italy, volumn 2, pp. 627-634, 1998.
9. Chen YM, Lee C-M. Molecular epidemiology of HIV-1 in Taiwan: heterosexual
males with HIV-1 E had significantly higher rate of transmission than those with
HIV-1 B. Proceedings of the 12th World AIDS Conference. Monduzzi Editore, Italy,
volumn 3, pp. 29-35, 1998.
10. Chen YM. HIV/AIDS in Taiwan. In AIDS in Asia, Lu YC and Essex M (ed.), p.p.
135-144, Kluwer Academic Publisher. 2004.
11. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic
polymorphism of glycine N-methyltransferase gene in hepatocellular carcinoma. In
Hormonal Carcinogenesis IV, Li JJ, Li SA and Llombart-Bosch A (ed.), p.p.
293-299, 2004.
12. Hsieh JL, Huang CY, Sun CT and Chen YM. Using the CAMIM Small-World
Epidemic Model to Analyze Public Health Policies. In Proceedings of Western
Multiconference, New Orleans, LA, pp. 63-69, 2005.
13. Sumodhee C., Hsieh J.L., Sun C.T., Huang C.Y., and Chen Y.M. Impact of Social
Behaviors on HIV Epidemic: A Computer Simulation View. In Proceedings of IEEE
Computational Intelligence for Modelling Control and Automation (CIMCA’05),
Vienna, Austria, pp. 130-134. (IEEE), 2005.
14. Chen YM. The 2003 SARS outbreaks in Taiwan. Growing infections in Asia. Lu YC,
Essex M and Robert B (eds.), Springer, pp. 119-134, 2008.
15. Wang SF and Chen YM. Chapter 5, The Interactions between Avian H5N1 Influenza
Virus and Dendritic Cell-Specific ICAM-3 Grabbing Non-Integrin (DC-SIGN).
Global View at Fight against Influenza. (Nova Science Publishers), In press, 2009.
16. Wang SF and Chen YM. The Emergence of HIV-1 Circulating Recombinant Form
07_BC Strains in Taiwan. Emerging Infectious Diseases: Global Trends,
Surveillance and Eradication. (Nova Science Publishers). In press, 2009.
17. Li P and Chen YM. Introduction. Is it HIV? A handbook for health care providers. Ed.
Menon A., Kamarulzaman A. Australian Society for HIV Medicine. P.p. 6-8, 2009.
Chinese articles:
17
1.
2.
3.
4.
5.
6.
[愛滋世界]。陳宜民。翻譯自 Jonathann Mann AIDS in the World. 2nd edtion. 1999.
（全書共 632 頁）。預防醫學出版社出版。
[預防醫學]。陳宜民。巨流出版社。
[愛之新生]。陳宜民主編。第六版。2008.
[第三章：愛滋病病毒之分子流行病學] 。藍郁青，陳宜民。[愛滋病學]第二
版，。pp. 24-34, 2006.
[第二十六章：愛滋病疫苗研發現況及未來展望]。林郁婷，陳宜民。[愛滋病
學]第二版。pp. 332-344, 2006.
[諾貝爾生醫獎─人類乳突病毒與愛滋病病毒]。陳宜民。[科學月刊]。2008, 12
月號。468 期，924-931 頁。
Television or DVD Interviews
CDC, 愛在擁抱， 2008
國科會，認識病毒， 2008
Asian Harm Reduction Association, 台灣愛滋減害成效報導 （在 2009 International
Harm Reduction Conference 播出）
公共電視 有話好說 新型流感病毒專輯 2009-4-27
公共電視 有話好說 新型流感病毒專輯 2009-4-29
公共電視 有話好說 新型流感病毒專輯 2009-4-30
民視 新聞最前線 2009-5-2
18
Conference Abstracts
1.
2.
3.
4.
5.
6.
7.
Chen YM, Lee TH, Samuel KP et al. Antibody response to different regions of
HTLV-1 gp61 in asymptomatic carriers. ATL patients and individuals with TSP. The
Second International HTLV Meeting, Trinidad. Feb. 1989.
Chen YM, Lee TH, Samuel KP et al. Antibody reactivity to different regions of
HTLV-1 gp61 in infected people. RNA tumor virus meeting. Cold Spring Harbor,
USA. May 1989.
Chen YM, Lee TH, Samuel KP et al. Antibody reactivity to different regions of
HTLV-1 gp61 in infected people Annual meeting of American Society of
Microbiology, West Ontario, Canada. Sep. 1989.
Chen YM, Okayama A, Lee TH et al. Antibody reactivity of different high-risk
groups to HTLV-1 ENV and Tax recombinant protein. Annual Meeting of Lab of
Tumor Immunology, NIH, MD, USA. Sep. 1989.
Chen YM, Okayama A, Lee TH et al. Sexual transmission of HTLV-1 associated
with the presence of the anti-Tax antibody. The Third International HTLV meeting,
Hawaii. April 1990.
Chen YM, Gomez-Lucia, E., Okayama, A. et al. The antiobdy profile of early
HTLV-1 infection. The Third International HTLV meeting, Hawaii. April 1990.
Chen YM, Lee TH, Wiktor SZ et al. Mapping the type-specific epitopes on the
HTLV-1 and -II envelope glycoprotein. RNA tumor virus meeting. Cold Spring
Harbor, USA. May 1990.
8. Gomez-Lucia E, Chen YM, Yu Q-C, Essex M. Experimental infeciton of monocytes
by HTLV. RNA tumor virus meeting. Cold Spring Harbor, USA. May 1990.
9. Chen YM, Lee TH, Essex M. HTLV-1 Envelope glycoprotein:the biological and
epidemiological significance. International Human Retro virology: HIV & HTLV
Conference, Taipei, R.O.C. Sep. 1990.
10. Chen YM, Wiktor SZ, Shaw GM. et al. Type-specific antigens for serological
discrimination of HTLV-I and HTLV-II infection. The fourth International HTLV
meeting. Jamaica, Feb. 1991.
11. Chen YM, Samuel KP, Blattner W et al. Mapping the type-specific regions on
HTLV-I and HTLV-II envelope glycoprotein. International AIDS Conference.
Florance Italy, June 1991.
12. Chen YM, Zhang X-g, Dahl C. et al. Delineation of type-specific regions on HTLV
envelope glycoproteins and its serological application. The Sixth International AIDS
in Africa Conference. Dakar, Senegal. Dec. 1991.
13. Chen YM. Delineation of type-specific regions on HTLV envelope glycoproteins by
19
Recombinant protein-Western blot assay and ADCC. The NIH HTLV
vaccine-perspective workshop. Bethesda, USA. Jan. 1992.
14. Chen YM. Delineation of the HTLV type-specific regions by recombinant Env
proteins and ADCC assays. The Second International Taipei AIDS Conference.
Taipei, ROC. May.
15. Chen YM, Kanki PJ, Jang YJ, et al. Isolation of simian T-lymphotropic virus type II
(STLV-II) from new world monkeys. The IXth International Conference of AIDS,
Berlin. 1993.
16. Jen I, Lan JF, Lin HT, Chen YM. A modified aids risk reduction model (ARRM) for
female sex workers in Taiwan. The IXth International Conference of AIDS, Berlin,
1993.
17. Chen YM, Kanki PJ, Jang YJ, et al. Isolation of simian T-lymphotropic virus type II
(STLV-II) from new world monkeys. Retroviruses meeting. Cold Spring Harbor,
USA. May 1993.
18. Lee MS, Chen YM, Chen SH, King CC, Wu YC, Horng CB, Chou P. Evaluation of
two hepatitis B virus immunization programs in an isolated islet-Kinmen, Fukien,
Republic of China, 1993. The third International Conference on Viral Disease,
Kunming, China, 1993.
19. Chen YM, Sheu T-T, Lee CM, Jang Y-J. The V3 region of HIV-1 isolates prevalent
in Taiwan contains a unique signature and E subtype sequence. The Xth International
Conference on AIDS, Yokohama, Japan, August 1994.
20. Jen I, Chen YM. The seropositive rates of HIV-1, HTLV-I, syphilis, and HBV
infections among illegal sex workers and servants in Taipei city. The Third Taipei
International AIDS Conference. Taiwan, ROC. August 1994.
21. Chin W-Y, Chang L-Y, Chou P, Chen YM. An evaluation of the impact of an AIDS
education program offered to beauty parlor personnel in the Song-San District of
Taipei, Taiwan. The Third Taipei International AIDS Conference, Taiwan, ROC.
August 1994.
22. Yao C, Kuo H-S, Chen YM. Economic analyses of the blood screening programs for
HIV-1 and HIV-2 in the blood donation centers in Taiwan. The Third Taipei
International AIDS Conference. Taiwan, ROC. August 1994.
23. Chen YM, Lin H-C, Whang-Peng J. Molecular epidemiology of human
immunodeficiency virus infection in Taiwan. First APSN International Symposium
and Workshop, Singapore, August 1994.
24. Chen YJ, Jang YJ, Lee MD, Liu MH, Chen PH, Whang-Peng J, Chen YM. A novel
mitochondrial ADP/ATP translocase gene identified from human gastric carcinoma
tissue by mRNA differential display. The World Congress of Gastroenterology. Los
Angeles, CA, USA, October 1994.
20
25. Chen YM, Lin H-C, Whang-Peng J. Molecular epidemiology and phylogenetic tree
analysis of HIV-1 infection in Taiwan. 7th Asian-Pacific Congress of Clinical
Biochemistry, Bangkok, Thailand, September 1995.
26. Chen YJ, Lee MD, Liu MH, Chen PH, Chen YM. The study of p16 (MTS1) gene
expression in gastric cancer cell lines and uncultured gastric cancers. The Society of
Surgical Oncology's 48th Annual Cancer Symposium, Boston, USA. March 1995.
27. Chen YM. Differential diagnosis of HIV-1 vs. HIV-2, HTLV-I vs. HTLV-II and
HIV-1 subtyping. International Symposium on Diagnosis of Viral and Chlamydial
Infection. Tainan, ROC. March 1996.
28. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. Retroviruses meeting, Cold Spring
Harbor, USA. May 1996.
29. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. Annual meeting for Chinese Society of
Oncology, Taipei, Taiwan. May 1996.
30. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. The XIth International Conference on
AIDS, Vancuver, Canada. August 1996.
31. Chen YM. Current situation of HIV-1 infection in Taiwan, a community report.
Global response to HIV/AIDS from Chinese communities. An official satellite
symposium of the XIth International Conference on AIDS, Vancouver, Canada,
August 1996.
32. Chen YM, Chen S-H, Fu C-Y, Chen J-Y, and Osame M. Antibody reactivities to p53
and HTLV-I regulatory proteins- tax, rex and tof in HTLV-I infected people. The 4th
International AIDS Conference, Taipei, Taiwan. December 1996.
33. Yao C, Wang W-W, Chung Y-M, Su Y-L, Liu C-Y, and Chen YM.
Transfusion-acquired AIDS In Taiwan. The 4th International AIDS Conference,
Taipei, Taiwan. December 1996.
34. Chen YM, Ting S-T, Liu W-T, Pan W-H, Chou P. Community-based molecular
epidemiology of human T-cell leukemia virus type I infection in Kin-hu, Kinmen and
three townships in Taiwan. The 4th International AIDS Conference, Taipei, ROC.
December 1996.
35. Jen I, Chang L-Y, Lin R-Y, Chen YM. Survey of knowledge, attitudes and practices
concerning AIDS among female sex workers in Taipei, Taiwan. The 4th
International AIDS Conference, Taipei, ROC. December 1996.
21
36. Chen YM, Lin C-C, Lin R-Y. Surveys of HIV-1, HTLV-I and other sexually
transmitted infections (STI) among female sex workers in Taipei, Taiwan. The 4th
International AIDS Conference, Taipei, ROC. December 1996.
37. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. Retroviruses meeting, Cold Spring
Harbor, USA. May 1996.
38. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. Annual meeting for Chinese Society of
Oncology, Taipei, Taiwan. May 1996.
39. Shiu J-YA, Tzeng S-J, Chen Y-J, Lui W-Y, Chen YM. cDNA cloning and sequencing
of human glycine N-methyl transferase whose expression is diminished in human
hepatocellular carcinoma. Annual meeting of Chinese Society of Oncology, Taiepi,
Taiwan. May 1996. (*The first award of the poster competition).
40. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I
infected people with different clinical status. The XIth International Conference on
AIDS, Vancuver, Canada. August 1996.
41. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing
clinical status. VIII International Conference on Human Retrovirology: HTLV. Rio
de Janeiro, Brazil. June 1997.
42. Chen YM, Ting S-T, Lee C-M, Pan W-H, Saitou N, Chou P. Population-based
molecular epidemiology of human T-cell leukemia virus type I in Taiwan and
Kinmen islands. VIII International Conference on Human Retrovirology: HTLV. Rio
de Janeiro, Brazil. June 1997.
43. Yu PS, Jen I, Lin C-C, Lin R-Y, Chen YM. Surveys of HIV-1 HTLV-I and other
sexually transmitted diseases among female sex workers in Taipei city and
prefectures, Taiwan from 1993 to 1996. 4th International Congress of the AIDS in
the Asia and Pacific. Manila, Philippine. Oct. 1997.
44. Chen YM. Current situation of HIV-1 infection in Taiwan, a community report.
Global response to HIV/AIDS from Chinese communities. 4th International
Congress of the AIDS in the Asia and Pacific. Manila, Philippine. Oct. 1997.
45. Chen YM, Shiu J-Y, Tzeng SJ, Lui W-Y. Characterization of glycine
N-methyltransferase gene expression in human hepatocellular carcinoma. Regulation
of Liver Gene Expression in Health & Disease. Cold Spring Harbor Laboratory, New
York, USA. April 1997.
22
46. Chen Y-J, Shih L-S, Chang J-G, Whang-Peng J, Chen YM. Frequent detection of
aberrant RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. The
2nd Annual Taiwan Joint Cancer Conference. Taiepi, ROC. May 1997.
47. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor
protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing
clinical status. VIII International Conference on Human Retrovirology: HTLV. Rio
de Janeiro, Brazil. June 1997.
48. Chen YM. Comparison of a modified HIV-1 Monitor test and a branched DNA assay
for the quantitation of HIV-1 RNA in triple therapy. 1998 Bangkok Symposium on
HIV Medicine, Bangkok, Thailand. January 1998.
49. Chen YM. Comparison of a modified HIV-1 Monitor test and a branched DNA assay
for the quantitation of HIV-1 RNA in triple therapy. 1998 Taipei Symposium on
Current Treatment and Vaccine Development for HIV Infection. Taipei, ROC. April
1998.
50. Chen YM, Lin R-H, Fu C-Y, Lin R-Y, Syu W-J. Decreasing levels of anti-Nef
antibody correlate with increasing viral loads in HIV-1 infected people with differing
clinical status. The 12th World AIDS Conference. Geneva. June 1998.
51. Chen YM, Lee C-M, Lin R-Y. Molecular Epidemiology of HIV-1 in Taiwan:
Heterosexual Males with HIV-1 E Had Significantly Higher Rate of Transmission
than Those with HIV-1 B. The 12th World AIDS Conference. Geneva. June 1998.
52. Chen YM. The strategies of advocating AIDS prevention and treatment in Taiwan.
Global response to HIV/AIDS from Chinese communities. An official satellite
symposium of the 12th World AIDS Conference. Geneva. June 1998.
53. Chen YM and Lee C-M. Molecular epidemiology of HIV-1 infection in Taiwan.
Annual Spring Meeting of the Taiwan Medical Assocation. May 1998.
54. Chen YM. The present situation of HIV epidemics and treatment in Taiwan.
International Conference on the Treatment of AIDS, Beijing, Oct. 1998
55. Chen YM. Decreasing levels of anti-Nef antibody correlate with increasing HIV-1
viral loads and AIDS disease progression. The 7th Annual Meeting of Chinese
Society of Immunology, Taipei, Nov. 1998.
56. Lee C-M, Lin R-H, Syu W-J, Chen S-C, Chen YM. A Study of the Anti-Nef
Antibody as a Serological Marker for AIDS Disease Progression. The 30th Annual
Meeting of Chinese Society of Microbiology, Taipei, Nov. 1998.
57. Hsu Y, Chen Y-J, Chen S-T, Chen YM. Characterization of Rb and CDKN2
(p16INK4A/MTS1) tumore suppressor genes in human esophageal carcinoma. The
3rd Taiwan Joint Cancer Conference. Taipei, April 1998. (*Among 59 posters
participated in the competition, it has won the top 8 award).Lin J-R V, Lee C-M,
Hsieh
23
58. L-L, Liu T-Y, Chen YM. The Interaction of Glycine N-methyltransferase and
Carcinogens- (Benzo[a]pyrene and Aflatoxin B1) in Liver Cancer Cells. The 30th
Annual Meeting of Chinese Society of Microbiology, Taipei, Nov. 1998.
59. Chen YM. Current situation of HIV infection and prevention strategy in gay
community in Taiwan. (Invited speaker) UNAIDS and ASAP Workshop on MSM.
Singapore, Feb. 1999.
60. Chen YM, Lee C-M, Lin R-H, Syu W-J, Chen S-C. Antibody Responses to HIV-1
Nef and Gag Proteins Correlate with Viral Loads and AIDS Disease Progression. 5th
International AIDS Conference in Taipei. Feb. 1999.
61. Chen YM, Lee C-M, Lin R-Y, Chen S-C. Molecular Epidemiology and Trends of
HIV Subtypes in Taiwan. 5th International AIDS Conference in Taipei. Feb. 1999.
62. Chen YM, Lin R-H, Lee C-M, and Syu W-J. Evaluation of the anti-HIV-1-Gag and
Nef Antibody Reactivities as Clinical Markers for AIDS Disease Progression and
Response to Triple Therapy. (Invited speaker). 3rd International Symposium on
Clinical Virology, Tai-Nan, Taiwan, march 1999.
63. Chen YM, Huang K-L, Chen S-C, Chang H-J. Molecular epidemiology of HIV-1
Infection in Taiwan. Fifth International Congress on AIDS in Asia and Pacific. Kuala
Lumpur. (Oral) Oct. 1999.
64. Chen YM. The present situation of human right issues of HIV/AIDS patients in
Taiwan. (Invited speaker). Fifth International Congress on AIDS in Asia and Pacific.
Kuala Lumpur. Oct. 1999.
65. Chen YM, Lin J-R V, Lee C-M, Lin C-H, Hsieh L-L, Yang S-C, Liu T-Y, Wong F-H.
The Interaction of Glycine N-methyltransferase and Carcinogens- (Benzo[a]pyrene
and Aflatoxin B1) in Liver Cancer Cells. Annual Meeting of Chinese Society of
Oncology, Taipei, April 1999.
66. Chen YM, Lee C-M, Lin J-R V, Chen L-Y, Lin C-H, Hsieh L-L, Yang S-C, Liu T-Y,
Wong F-H. Glycine-N-methyltransferase-gene expression and the
hepatocarcinogenesis. (Invited speaker) 2nd International Symposium on liver
Cirrhosis and Liver Cancer. Kyoto, Japan, June 1999.
67. Chen YM. Molecular epidemiology of HIV-1 and HTLV-I in Taiwan. Invited speaker
at the Branch of Cancer Epidemiology and Genetics, National Cancer Institute, NIH,
Bethesda, Maryland, USA, Feb. 2000.
68. Chen YM. Decreasing levels of anti-Nef antibody correlate with increasing viral
loads and AIDS disease progression. Invited speaker at the Symposium on Recent
Advancement of HIV Therapy. Taipei, Feb. 2000.
69. Chen YM. Molecular epidemiology and Trends of HIV-1 infection in Taiwan. Invited
speaker at the Year 2000 Taipei Symposium on the Clinical Management and
Laboratory Diagnosis of AIDS. Taiepi, April 2000.
24
70. Chen YM. Anti-Tat antibody and subtype E have synergistic effect on the sexual
transmission of HIV-1. XIII International AIDS Conference. (Oral) Durban, South
Africa, July 2000.
71. Chen YM. The AIDS Epidemics and the Human Right Issues in Taiwan. Invited
speaker at the Satellite Symposium on “HIV/AIDS in Chinese Community-Threats
and Opportunities in the New Millennium” XIII International AIDS Conference.
July 2000.
72. Chen YM. Virologic markers associated with AIDS disease progression. Invited
speaker at the National Annual AIDS Meeting of Philippine. Manila, Oct. 2000.
73. Chen YM. Molecular Epidemiology of HIV-1 Subtypes: Methodology and
Application. Invited speaker at the National Annual AIDS Meeting of Philippine.
Manila, Oct. 2000.
74. Chen YM. GNMT and liver cancer. Invited speaker at the Laboratory of Population
Genetics, National Cancer Institute, NIH, Bethesda, Feb., 2000.
75. Chen YM, Chen LY, Lin JR, Liu TY, Yang-Feng TL. Genomic Structure,
Chromosomal Localization and Functional Study of the Human Glycine
N-methyltransferase Gene. The 50th Annual Meeting of American Society of Human
Genetics. Philadelphia, USA, Oct. 2000.
76. Tseng TL, Chen YM, Struewing JP, Buetow K. Identification and characterization of
novel polymorphisms/mutation in the glycine N-methyltransferase gene in liver
cancer. The 50th Annual Meeting of American Society of Human Genetics. Oct.
Philadelphia, USA, 2000.
77. Chen YM. Functional study and characterization of novel polymorphisms of GNMT
gene in liver cancer patients. In the “Recent advanced diagnosis and treatment in
HCC meeting” held by the Chinese Society of Clinical Oncology, Dec. 2000.
78. Chen YM, Chung CL, Jen I, Lan YC, Wu SI, Hsu H. Molecular Epidemiology and
temporal trends of HIV-1 subtypes in Taiwan and a survey on the HIV-1, syphilis
and sexual behavior among men attending gay saunas in Taipei City. International
AIDS Conference in Taiwan. (Invited speaker) March 2001.
79. Chen YM, Chung CL, Wu SI, Hsu H. A Survey on the HIV-1, syphilis and sexual
Behavior Among Men Attending Gay Saunas in Taipei City. 2001 Hong Kong AIDS
Meeting. August 2001.
80. Chen YM, Chung CL, Wu SI, Hsu H. An HIV and STD Prevention Program for Men
Attending Gay Saunas in Taipei City. 2001 Hong Kong AIDS Meeting. August
2001.
81. Chen YM, Chung CL, Jen I, Lan YC, Wu SI, Hsu H. Surveys on the HIV-1, syphilis
and sexual behavior among men attending gay saunas in Taipei City. The 6th ICAAP
in Melbourne, Australia, Oct. 2001.
25
82. Chen YM, Lei WY, Huang YC, Wu SI. The seroconversion of anti-Vpu antibody is
associated with the recovery of humeral immunity in patients on highly active
antiretroviral therapy. The 6th ICAAP in Melbourne, Australia, Oct. 2001.
83. Chen YM. Molecular epidemiology of HIV-1 and surveys of STDs in gay saunas in
Taiwan. (invited seminar) The 15th Annual Meeting of Japanese AIDS Society, Nov
2001.
84. Chen YM. Clinical Implications of anti-Nef and anti-Vpu antibodies in patients on
HAART. (invited seminar) The 15th Annual Meeting of Japanese AIDS Society, Nov
2001.
85. Tseng TL, Chen YM, Shih YP, Buetow KH. Genotypic and phenotypic
characterization of a putative tumor suppressor gene, GNMT, in liver cancer. The 51st
Annual Meeting of American Society of Human Genetics. San Diego, USA, Oct
2001.
86. Chen YM, Lee CM, Shih YP, Tseng TL, Buetow K. Delineation of mechanism of
glycine N-methyltransferase gene control in liver cancer. The 51st Annual Meeting of
American Society of Human Genetics. San Diego, USA, Oct 2001.
87. Chen YM. Delineation of the mechanism of glycine N-methyltransferase gene control
in hepatocellular carcinoma. The 4th France-Taiwan Conference on Virus and Cancer.
Kenting, Taiwan, Nov. 2001.
88. Shih YP, Huang YC, Tseng TL, Chen YM. A Study of the Glycine
N-methyltransferase Genotypic and Phenotypic Characterization in Human Heptoma
Cell Lines. The 35th Annual Meeting of Chinese Society of Microbiology, Taipei,
Dec. 2001.
89. Chen SY, Wong FH, Liu TY, Chen YM. A Study of the Interaction between
4S-PAH-binding Protein (GNMT) and Benzo[a]pyrene. The 35th Annual Meeting of
Chinese Society of Microbiology, Taipei, Dec. 2001.
90. Lee CM, Chen YM. A Study of the Mechanism of the Human GNMT Gene Control
in Hepatocellular Carcinoma. The 35th Annual Meeting of Chinese Society of
Microbiology, Taipei, Dec. 2001.
91. Elbeik E, Lan YC, Dileanis JA, Marlowe N, Ng V, Chen YM. Prevalence of HIV-1
genotypic mutations in the protease and reverse transcriptase genes from infected
individuals in Taiwan: Treatment challenges. The XIV International AIDS
Conference, Barcelona, Spain, July, 2002.
92. Jen I, Chen YM. Advocating a new health policy for mandatory condom distribution
and nationwide behavior surveillance system establishment in Taiwan. The XIV
International AIDS Conference, Barcelona, Spain, July, 2002.
93. Hung CP, Wang WC, Jen I, Chen YM. Two-year consecutive survey of the
prevalence rates of HIV and syphilis infection among men who have sex with men
26
attending saunas in Taipei. The XIV International AIDS Conference, Barcelona,
94.
95.
96.
97.
Spain, July, 2002.
Chen YM, Elbeik E, Lan YC. Molecular epidemiology of HIV-1 subtypes and
drug-resistant strains in Taiwan. The Third Annual HDR meeting. Virginia, 2002.
Chen YM. SARS Prevention in Taiwan. International Conference on SARS Control.
Beijing. April 2003.
Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of Genetic
Polymorphism of Glycine N-Methyltransferase Gene in Hepatocellular Carcinoma.
4th volume of Hormonal Carcinogenesis. The 4th International Symposium on
Hormonal Carcinogenesis, Spain, Jun. 2003.
Chen YM. Molecular epidemiology of HIV-1 subtypes and SARS coronavirus
infection in Taiwan. UCLA School of Public Health. Invited seminar. August 11,
2003.
98. Chen YM, Liang CY, Shih YP, et al. Establishment of a confirmatory test for SARS
infection. International Conference on SARS. Beijing. August 2003.
99. Chen YM. The establishment and operation of the PWA’s Rights’ Advocacy
Association in Taiwan. International Seminars on HIV/AIDS: Social Behavior,
Stigma and Discrimination. Beijing, China, July 2004.
100. Lan YC, Elbeik T, Lai SF, Chen KT, Leu HS, Cheng S H, Wong W W, Wong J C,
Chen YM. Molecular Epidemiology of HIV-1 Subtypes and Drug Resistant Strains
in Taiwan: The resurgence of HIV-1 subtype B in Taiwan during 1999 to 2000
survey. The XV International AIDS Conference, Bangkok Thailand, July 2004.
101. Lin YT, Hsieh SL, Chen YJ, Lai SF, Chen YM. The serum level of the decoy
receptor 3 (DcR3) is associated with HIV-1 subtype and AIDS disease progression.
(oral presentation) The XV International AIDS Conference, Bangkok Thailand, July
2004.
102. Lai SF, Hong CP, Lan YC, Chen KT, Wong WW, Hu BS, Chen YM. Molecular
epidemiology of HIV-1 in men who have sex with men from gay saunas in Taiwan
from 2000 to 2003. The XV International AIDS Conference, Bangkok Thailand, July
2004.
103. Chen YM, Lan YC, Yang JY et al., Molecular epidemiology of SARS coronavirus
infections in Taiwan. 2004 International Symposium on the Prevention and Control
of SARS and Avian Flu. Beijing, China, August 22 to 24, 2004.
104. Chen YM. Molecular epidemiology of HIV-1 and SARS infections in Taiwan.
(Keynote speech) The 6th Guangdong, Hong Kong, Macau and Taiwan Conference
on Preventive Medicine. Macau, Oct. 30, 2004.
105. Lin YT, Hsieh SL, Chen YJ, Lai SF, Chen YM. The serum level of the decoy
receptor 3 (DcR3) is associated with HIV-1 subtype and AIDS disease progression.
27
The 6th Guangdong, Hong Kong, Macau and Taiwan Conference on Preventive
Medicine. Macau, Oct. 30, 2004.
106. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic
polymorphism of Glycine N-Methyltransferase gene in prostate cancer. The 6th
Guangdong, Hong Kong, Macau and Taiwan Conference on Preventive Medicine.
Macau, Oct. 30, 2004.
107. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic
polymorphism of Glycine N-Methyltransferase gene in prostate cancer. The 54th
Annual Meeting of American Society of Human Genetics. Toronto, Canada, Oct.
2004.
108. Hsieh JL, Huang CY, Sun CT, Chen YM. Using the CAMIM small-world epidemic
model to analyze public health policies. Western Multiconference 2005.
109. Tsai TT Tsai, Chuang PH, Lin IF, Chen YM, Wu WH, Chang HJ, Chuang JH. Using
Claims Data for Establishing a Syndromic Surveillance System in Taipei City. In
International Association for Computer Information Systems Conference. 2005.
110. Chen SY, Lee CM, Liu HH, Darbha R, Hsieh LL and Chen YM. Glycine
N-methyltransferase is a novel cytosolic receptor for aflatoxin B1 and it can prevent
AFB1-DNA adducts formation. The Twentieth National Biomedical Combined
Conference. Taipei, Taiwan, March 26-27, 2005.
111. Huang YC, Chung MY, Chang YH, Huang JSW, Ho MTD, Pan CC Wu TL, Chen
YM. Genetic polymorphism and expression of glycine N-methyltransferase (GNMT)
gene in prostate cancer. The Twentieth National Biomedical Combined Conference.
Taipei, Taiwan, March 26-27, 2005.
112. Chen YM. Molecular epidemiology and serological diagnosis of SARS infection in
Taiwan. Invited speaker at the Tartu University, Tartu, Estonia, April 6, 2005.
113. Chen YM. Evolving HIV epidemic in Taiwan: context, current situation and response.
Invited speaker at the Estonia National Medical days. Tallinnas, Estonia, April 7-8,
2005.
114. Sumodhee C., Hsieh J.L., Sun C.T., Huang C.Y., and Chen YM. Impact of Social
Behaviors on HIV Epidemic: A Computer Simulation View. In Proceedings of IEEE
Computational Intelligence for Modelling Control and Automation (CIMCA’2005),
Vienna, Austria.
115. Medah Isaie, Lai SF, Chang YU, Li CC, Kang HF, and Chen YM. Knowledge,
attitude, and practices towards HIV/AIDS among first-year university students in
Taiwan-A National Survey. 7th International Congress on AIDS in Asia and the
Pacific, Kobe, Japan, July. 2005.
116. Chen YM, Lai SF, Lan YC, Chen KH, Chen YJ. Molecular epidemiology of HIV-1
infection among injecting drug users in Taiwan-Report of an emergent situation. 7th
28
International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
117. Wang CC, Wong WW, Chen YM. The effect of HAART on the disease progression
of HIV/AIDS patients co-infected with HBV or HCV. 7th International Congress on
AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
118. LinYT, Chen YJ, Lai SF, Hsieh SL, Chen YM. Serum decoy receptor 3 (DcR3) level
is associated with HIV-1 subtype B and slower AIDS disease progression. 7th
International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
119. Tsui JJ , Lai SF, Chen YM, Wong WW, Yang SY. A Study of the Holistic Care
Model for HIV/AIDS patients. 7th International Congress on AIDS in Asia and the
Pacific, Kobe, Japan, July. 2005.
120. Chang YR, Medah Isaie, Lai SF, Kang FH, and Chen YM. Advocacy for
establishment of a guideline for the management of Students Living with HIV/AIDS
at schools in Taiwan. 7th International Congress on AIDS in Asia and the Pacific,
Kobe, Japan, July. 2005.
121. Chang JL, Chen YM, Ko NY. Help PLWHAs Being Familiar to Medical Care
Systems: The HAART Partnership of Living with Hope Organization in Taiwan.
7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
122. Lee YM, Lai SF, Chen KD, Wong WW, Chen YM. Molecular Epidemiology of
Hepatitis C Virus Subtypes in HIV/AIDS Patients in Taiwan. 7th International
Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
123. Lai SF, Lan YC, Lin YH, Chen KT,Wong WW,Chen YM. Molecular epidemiology of
HIV-1 infection in men who have sex with men (MSM) from gay saunas in Taiwan
from 2003 to 2004. 7th International Congress on AIDS in Asia and the Pacific,
Kobe, Japan, July. 2005.
124. Lan YC, Elbeik Tarek, Lai SF, Chen KD, Leu HS, Cheng SH, Wong WW, Wong JC,
Chen YM. Molecular Epidemiology of HIV-1 Subtypes and Prevalence of HIV-1
Genotypic Drug Resistant Strains in Taiwan. 7th International Congress on AIDS in
Asia and the Pacific, Kobe, Japan, July. 2005.
125. Hsu SC, Lin SR, Haung HC, Wang CC, Chen YM. Display of AIDS memorial quilts
and at-risk babies crib quilts to advocate MTCT program in Taiwan. 7th International
Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
126. Chang CJ, Wang CC, Chen YM. Use CD4 Counts, HBV and HCV Tests to Enhance
the Participation and Effects of AIDS Education among PLWHAs in Prisons. 7th
International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005.
127. Chen YM. Molecular epidemiology of HIV-1 infection among injecting drug users in
Taiwan. 2005 Taipei International Conference on Drug Control and Addition
Treatment. Taipei, Taiwan, November 22-24, 2005.
128. Lee CM, Chen SY, Huang CYF, Lee YCG, Chen YM. Benzo[a]pyrene and Glycine
29
N-Methyltransferse Interactions: Gene Expression Profiles of the Liver
Detoxification Pathway. The 9th Asian-Pacific Conference on Transcription,
ACT-IX. December. December 15-17, 2005.
129. Chen YM. Establishment of a transgenic mouse model to study the interaction
between GNMT and aflatoxin B1. 5th NHRI Conference on Viral Hepatitis and
Hepatocellular Carcinoma. Chu-nan, Taiwan. March 24-25, 2006.
130. Chen YM. HIV-1 drug resistance surveillance of treatment naïve persons in a clinical
network. Antiretroviral Resistance Prevention, Surveillance and Monitoring in Asia
World Health Organization, Global AIDS Program – Vietnam and Asia Regional
Global AIDS Program. Hanoi, Vietnam March 27-31, 2006.
131. Chen YM. Molecular epidemiology, phylogenetic and genomic analysis of HIV-1
circulating recombinant form 07_BC among injecting drug users in Taiwan. First
Taiwan-Netherlands Workshop on Pathogenomics. Amsterdam, Netherlands, April
9-11, 2006.
132. Chen YM. Trade Related Infections, Traveling and the Spread of Emerging Infectious
Diseases. 2006 International Workshop on “WTO Agreement and Public Health”.
May 3-4. Taipei, Taiwan.
133. Hsieh JL, Huang CY, Sun CT, Chen YM, Chu D. Using the Agent-based Epidemic
Simulation CAMIM to Assess Public Health Policies. 2006 Mexican International
Conference on Artificial Intelligence. Mexico.
134. Lan YC, Lin YT, Chen JJ, Liu TT, Chen YM. Phylogenetic and genomic analyses of
six full-length CRF07_BC variants isolated from injecting drug users in Taiwan.
XVI International AIDS Conference, Toronto, Canada. (abstract No. CDA0118)
135. Jang YR, Jiang YH, Chuang SY, Zhou J, Lan YC, Wong WW, Chen YM. Taiwan
HIV observational database: baseline and retrospective data. XVI International AIDS
Conference, Toronto, Canada. (abstract No. CDC0013)
136. Chen YJ, Huang YH, Lan SF, Chen YM. Phylogenetic analysis of Taiwanese HIV-1
CRF08_BC strains: tracing the origin and dissemination of this CRF in Taiwan. XVI
International AIDS Conference, Toronto, Canada. (abstract No. CDC0365)
137. Hung KC, Chen YM. AIDS education combined with a display of AIDS memorial
quilts to raise awareness among teenagers in Taiwan. XVI International AIDS
Conference, Toronto, Canada. (abstract No. CDC1565).
138. Zhou J, Dore G, Chen YM, Law M. Hepatitis B and C virus coinfection among
patients with HIV in Asia HIV observational database. XVI International AIDS
Conference, Toronto, Canada. (abstract No. TUAB0302, oral presentation)
139. Chang KC, Chang CC, Mai CK, Jung KC, Chen YM. Development and
implementation of a harm reduction and AIDS education program in the detention
centers and prisons in Taiwan. XVI International AIDS Conference, Toronto, Canada.
30
(abstract No. THPE0732, poster presentation).
140. Chen YM, Huang YH, Chen CJ, Lai SF, Yang JY, Kuo HS. Molecular epidemiology
of HIV-1 in Taiwan: emergence of CRF07_BC among injecting drug users in
Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No.
MOPE0359. poster presenation)
141. Chen YM. Molecular epidemiology of HIV-1 Subtypes and Circulating Recombinant
Forms in Taiwan. Taiwan-Japan Conference on Infectious Disease Control, Taipei,
2006.
142. Chen YM. Molecular epidemiology of HIV-1 Subtypes in Taiwan. 8th International
Taipei AIDS conference. Taipei, 2006.
143. Chen YM. Molecular epidemiology of HIV-1 Subtypes in Taiwan. Taiwan Medical
Week. Invited speaker. Taipei, Nov. 13, 2006.
144. Liu SP and Chen YM. Characterization of a GNMT gene knockout mouse model. 8th
Meeting of Liver Cancer Study Group of Taiwan. Kaohsiung, Taiwan, Dec. 9, 2006.
145. Tsai TI, Chen YM, Yang SY, Huang YF, Kuo HS. Evaluating preliminary harm
reduction programs in Taiwan. 18th International Conference on the HR. Warsaw,
Poland, May13-17 2007.
146. Chen YM, Lin YT, Lan YC, Chen YJ, Huang YH, Lee CM, Liu TT, Wang CT.
Molecular epidemiology of HIV-1 infection and full-length genomic analysis of
circulating recombinant form 07_BC strains from injecting drug users in Taiwan.
Conference on HIV Pathogenesis, Treatment and Prevention. 4th IAS Conference on
HIV Pathogenesis and Treatment, Sydney, Australia, 22-25 July 2007. (Poster)
147. Jang YR, Zhou J, Chung SY, Wong WW, Chen YM. Prognostic markers related to
AIDS diagnoses and deaths among HIV-1/AIDS patients in Taiwan. Conference on
HIV Pathogenesis, Treatment and Prevention. 4th IAS Conference on HIV
Pathogenesis and Treatment, Sydney, Australia, 22-25 July 2007. (Poster)
148. Chang KC, Chang ZX, Huang CK, Chen JW and Chen YM. Development and
implement of an outreach and Peer education program in NSP station in Taiwan. 8th
International Congress on AIDS in Asia and the Pacific, Sri Lanka, August 19-23,
2007.
149. Chen YM, Lin YT, Lan YC, Chen YJ, Huang YH, Lee CM, Liu TT, Wang CT.
Molecular epidemiology of HIV-1 infection and full-length genomic analysis of
circulating recombinant form 07_BC strains from injecting drug users in Taiwan. 8th
International Congress on AIDS in Asia and the Pacific, Sri Lanka, 2007. (oral
presentation).
150. Chen YM. Molecular epidemiology of HIV-1 and HCV infections in Taiwan.
International Conference on AIDS and TB. Taipei, 2007. (Invited speaker).
151. Liu SP, Li YS, Chen YJ, Chiang EP, Li FY, Lee YH, Tsai TF, Hsiao M, Chen YM.
31
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage
disease in liver. The 57th ASHG, San Diego, California. Oct. 23, 2007.
152. Chen YM. Aim for Excellence: The experiences of international collaboration at
Yang-Ming University. UK-Taiwan Higher Education Conference, Taipei, Taiwan.
November 5, 2007. (Invited speaker).
153. Chen YM. Molecular epidemiology of HIV-1 and HCV infection in Taiwan. 2007
Annual Meeting of Taiwan Society of Biochemistry and Molecular Biology. Oct.
19-20, 2007. (Invited speaker).
154. Chen YM. Molecular epidemiology of HIV-1 and HCV infection in Taiwan.
International Conference on Control of Tropical Infectious Diseases and Cancer in
Taiwan and South Pacific. Nov. 10-11, 2007. (Invited speaker).
155. Chen YM. Review the history: epidemiology of SARS coronavirus infection in
Taiwan. 2007 International Symposium on Humanity Care in the Post-SARS Era.
Nov. 21-22, 2007. (Invited speaker).
156. Chen YM. Serological and genetic correlates of SARS coronavirus infection. 2007
International Symposium on Humanity Care in the Post-SARS Era. Nov. 21-22,
2007. (Invited speaker).
157. Chen YM. HIV-1 infection and harm reduction program in Taiwan. 21st Japanese
Society for AIDS Research Annual Meeting, Hiroshima, Nov30, 2007. (Invited
speaker).
158. Chen YM. Molecular epidemiology of HIV and HCV infection in Taiwan. 1st
UK-Taiwan International Networking for Young Scientists Symposium on Infection
and Immunity. (invited speaker) Taipei, March, 2008.
159. Chen YM. Characterization of a GNMT-/- mouse model for hepatocellular carcinoma.
Joint Symposium between National Yang-Ming University , Taiwan and University
of California San Diego. (invited speaker), San Diego, April 2008.
160. Chen YM. Searching for kinases and phosphatases associated with interaction
between GNMT and DEPDC6 using RNAi screen. Taiwan –Broad Institute Joint
Mini-symposium on RNAi Screen. (invited speaker), Taipei, May, 2008.
161. Lan YC, Lu CL, KH, Chen YM. Impact of a Harm Reduction Program on the
th
Prevention of HIV-1 Infection among Injecting Drug Users in Taiwan. (poster) 19
International Harm Reduction Association Conference, Spain, May, 2008.
162. Chen YM. Proteomic and epigenomic analyses of a GNMT-/- mouse model. Taiwan
Proteomics Society Eastern International Conference, Tzu Chi Medical Center,
(invited speaker), June, 2008.
163. Lan YC and Chen YM. Evaluation of the harm reduction program in Taiwan. XVII
International AIDS Conference, Mexico Coty, 3-8 August 2008 (oral presentation).
164. Liao YJ and Chen YM. Glycine N-methyltransferase is associated with gender
32
disparity in liver cancer susceptibility. 2008 Meeting on Mechanisms & Models of
Cancer. Cold Spring Harbor Laboratory, NY, August 13-17, 2008. (Poster)
165. Lee YM, Lee CM and Chen YM. Molecular epidemiology of HIV and HCV infection
among injection drug users in Taiwan. XVII International AIDS Conference, Mexico
Coty, 3-8 August 2008 (Poster).
166. YR Chang, WW Wang and Chen YM. Clinical epidemiology of HIV-1 infection in
Taiwan. XVII International AIDS Conference, Mexico Coty, 3-8 August 2008
(Poster).
167. Chen YM. Characterization of a glycine N-methyltransferase gene knockout mouse
model for hepatocellular carcinoma. International Symposium in Regeneration
Medicine. August 22, 2008, Taipei, Taiwan (invited speaker).
168. Chen YM, YJ Liao, SP Liu, TF Tsai. Glycine N-methyltransferase is associated with
gender disparity in liver cancer susceptibility. 2nd International Liver Cancer
Association Annual Conference. Chicago, September 5-7, 2008 (Poster).
169. Lyu SY, Peng EY, Chen YM, Morisky DE, Cheng SH. Potential causes of rapid
increase of HIV infection among injection drug users after SARS outbreak in Taiwan.
(Poster) presented at the 9th Taipei international conference on HIV/AIDS, Taipei,
Taiwan, 2008 (Poster).
170. Chen YM. How we promote human right protection issues for HIV-1/AIDS patients
in Taiwan. Presentation in Observatory of HIV and sexuality, in the Facultés
Universitaires Saint Louis, au Salon des Professeurs, rue du Marais 109, 5ème étage,
Belgium, 2008 (invited special seminar).
171. Chen YM. HIV-1 infection in Asia: How Harm Reduction Program Turn the Tide of
HIV-1 Epidemic in Taiwan. Presentation in Chu St. Pierre Forum. Department of
Infectious Diseases, Chu St. Pierre, The European AIDS Clinical Society (EACS).
Belgium. September 9, 2008 (invited special seminar).
172. Chen YM. Emerging Infectious Disease. 2008 Global Forum for Health Leaders.
November 3-4, Taipei, Taiwan. (invited speaker).
173. Chen YM. Molecular epidemiology of HIV-1 infection and evaluation of the harm
reduction program in Taiwan. Biostatistics Day Symposium. November 26, 2008,
Taichung, Taiwan (invited speaker).
174. Lee YM, Lin HJ, Chen YJ, Lee CM, Wang SF, Chang KY, Chen TL, Liu HF, Chen
YM. Molecular Epidemiology of HCV Genotypes among Injection Drug Users in
Taiwan: Identification of a new subtype 6v and unique recombinant form_2b6v. 11th
Western Pacific Congress on Chemotherapy and Infectious Diseases. (WPCCID),
November 29-December 3, Taipei, Taiwan (Poster).
175. Liao CF, Wang SF, Chen YM. Analysis of the DC-SIGN-interactive domains on the
envelop glycoprotein of HIV-1 CRF07_BC. 11th Western Pacific Congress on
33
Chemotherapy and Infectious Diseases. (WPCCID), November 29-December 3,
Taipei, Taiwan (Poster).
176. Chen YM. Evaluation of the harm reduction program in Taiwan. 2008 Healthy City
Symposium in Taipei. December 6-7, 2008. Taipei, Taiwan (invited speaker).
177. Chen YM. Epidemiology of HIV-1 infection and evaluation of harm reduction
program in Taiwan. The Asian Administrative Meeting on HIV/AIDS, Kunming,
Yunnan, China. Organized by Ministry of Health, Labor and Welfare of Japan,
March 18-19, 2009 (invited speaker).
178. Yen CH and Chen YM. Glycine N-methyltransferase affects the metabolism of
aflatoxin B1 and blocks its carcinogenic effect. 100th AACR meeting, April 18-22,
Denver, 2009. (poster).
179. Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang W J-S, Yi-Ming Arthur Chen
YMA. Association study of rs1447295 at 8q24 with prostate cancer in Taiwanese
men. World Chinese Urological Society Meeting. Chicago, April 2009. (oral
presentation).
180. Jan YR, Zhou J, Chuang SY, Wong WW, Chen YM. Impact of HBV and HCV
coinfection on the Outcomes of antiretroviral treatment (ART) and disease
progression in HIV-infected Patients in Taiwan. IAS (International AIDS Society
Meeting), July 19-22, 2009.
181. Chen YM, Chu YT, Kao DYT, Chiang SC, Wu SC. Risk of Cancer among People
Living with HIV/AIDS (PLWHA) in Taiwan 1997-2007. 9th ICAAP, August 8-13,
Bali, Indonesia.
182. Chen YM. Network of collaborating universities in health care and its education.
EAIE (European Association for International Education, oral presentation and
section organizer, Madrid, Spain, September 14-20, 2009.
183. Chen YM. Molecular epidemiology of HCV infection among HIV-1-infected IDU in
Taiwan. U.S. Japan Joint AIDS-Hepatitis Meeting. Portland, Oregon, September
19-21, 2009 (invited speaker).
184. Chen YM. Hepatitis B and C virus coninfection in the TREAT Asia HIV
Observational Database. U.S. Japan Joint AIDS-Hepatitis Meeting. Portland, Oregon,
September 19-21, 2009 (invited speaker).
185. Peng EY, Lyu SY, Morisky DE, Lan YC, Chen YM. Comparison of drug-using
experiences among female inmates by age groups in Taiwan. 137 APHA (American
Public Health Association) meeting, Philadelphia, USA, November 7-11, 2009.
186. Yang YC, Chen YM, Yeh CC, Ling MP, Wang RY, Lu CL, Chen KH, Lai JS, Lan
YC. Creating a HIV-1 infection risk model as a prevention tool for Injecting drug
users. Comparison of drug-using experiences among female inmates by age groups
in Taiwan. 137 APHA (American Public Health Association) meeting, Philadelphia,
34
USA, November 7-11, 2009.
187. Chen YM, Lan YC, Lyu SY. Evaluating the impact of harm-reduction program in
Taiwan from 2005-2008. 137 APHA (American Public Health Association) meeting,
Philadelphia, USA, November 7-11, 2009.
188. Chen YM. Molecular epidemiology of HCV infection among HIV-1-infected IDU
in Taiwan: identification of a new subtype 6w. The 2nd Taiwan NSC-Japan JST Joint
Meeting. Kyoto, Japan, November 16-17, 2009 (invited speaker).
189. Chen YM. Characterization of a glycine N-methyltransferase gene knockout mouse
model for hepatocellular carcinoma. Yamaguchi University, November 20, 2009
(invited speaker).
190. Lee YM, Chen YJ, Chen YM. Molecular epidemiology of HCV infection among
HIV-1-infected IDU in Taiwan: identification of a new subtype 6w. (poster) 17th
Conference of Retrovirology and Opportunistic Infection (CROI), February 16-19,
2010.
191. Oyomopito R, Phanuphak P, Sungkanuparph S, Kumarasamy N, Sirisanthana T, Li P,
Chen YM. Cohort Profile: The TREAT Asia Studies to Evaluate Resistance
Monitoring Study (TASER-M) - HIV Drug Resistance in the Asia-Pacific. IAS
Meeting, Vienna, Austria, July, 2010.
192. Chen YM, Chu YT, Kao DYT, Chiang SC, Law M, Sharp G, Wu SC. Risk of Cancer
among People Living with HIV/AIDS (PLWHA) in Taiwan 1997-2007. IAS
Meeting, Vienna, Austria, July, 2010.
193. Lan YC, Chen YM. Transmission origin of HIV-1 CRF01_AE and B subtype among
injecting drug user in Taiwan. 138th APHA Annual Meeting, Denver, CO. Nov. 6-10,
2010.
35