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LTE 199H1S, L0422 - Genes, Genomes and Us Not offered in 2015-16 Lecturers: Prof. A. Bruce [email protected] Since the completion of the human genome sequence, we now have access to more information than ever before about our genetic make-up. The human genome contains 3 billion base pairs of DNA, encoding an estimated 25,000 genes, which are the basic units of heredity. This course addresses questions such as what are genes, how are they identified and how does knowledge about genes impact society at large. Students will explore the basic concepts that explain the genetic foundations of complex traits, with a major focus on how this information is used to understand, treat and potentially prevent human diseases. Topics include gene therapy, personalized medicine, cloning and stem cells. The significance of genomic research for understanding human biology, and the social consequences that may result from it, are discussed and debated. Evaluation is based on class discussions, oral presentations and written assignments.