Download Successful Treatment of Stevens Johnson Syndrome

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Case Report: Successful Treatment of Stevens Johnson Syndrome-Toxic
Epidermal Necrolysis with Intravenous Immunoglobulin<br>
Author :
Bony Pramono, Ariyanto Harsono
Abstract :
Steven Johnson Syndrome is a serious disease of the skin characterized by triad of erythema
exudativum multiforme lesions affecting skin, orifices and eyes. Immunological basis of this
disease is hypersensitivity type III and IV. The differential diagnosis are Staphylococcal Scalded
Skin Syndrome and Toxic Epidermal Necrolysis. The mainstay of treatment is discontinuation of
previously given drugs. Supportive treatment consisting fluid therapy, skincare, symptomatic
and antibiotic for existing skin infection. Intravenous Immunoglobulins is used in severe skin
involvement and severe complications including eyes. The prognosis is generally good, fatal
outcome is usually due to delayed therapy and severe complication.