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Physiology (H), Part-II, Paper- IVA
1. (a) What is redox potential?
(b) Distinguish between oxidative phosphorylation and substrate level phosphorylation.
(c) Discuss with evidence the site of oxidative phosphorylation.
(d) Mention the sources of electrons for oxidation in the Electron Transport Chain.
OR
(a) Describe the rate-limiting steps of the glycolytic pathway.
(b)Discuss the anabolic role of TCA cycle.
2. (a) State the role of pyridoxal phosphate in transamination reactions.
(b) Discuss the role of carbamoyl synthase I in relation to urea formation.
(c) Discuss the synthesis of glycine from choline.
OR
(a) What are glucogenic amino acids? Give examples.
(b) Discuss the catabolic pathway of pyrimidine.
(c) What is Gout?
3. (a) Describe the process of cholesterol synthesis from Lanosterol.
(b) Calculate the total energetics of β-oxidation reaction of one molecule of palmitic acid.
OR
(a) What are 'Reactive Oxygen Species'? Give two examples.
(b) State the reactions catalyzed by Superoxide Dismutase and Glutathione Reductase in
combating oxidative stress
(c) Name two vitamins which can combat oxidative stress.
4. Write short notes on any two:
(a) Electrophoresis (b) TLC (c) RIA (d) ELISA
OR
(a) Write the application of radioactivity in the biological experiment
(b)Write principle and applications of SDS-PAGE.
5. (a) Discuss the role of restriction endonuclease in the formation of recombinant DNA.
(b) Write briefly the regulation of lac operon in E. coli in the presence of glucose and lactose.
OR
(a) What is gene therapy?
(b) What do you mean by codon-anticodon interaction?
(c) What is frame shift mutation?
(d) What is transgenic animal?
(e) What is oncogene? Give one example.