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Drug: Disease Everolimus Renal Cell Breast Cancer Carcinoma 2nd line treatment of metastatic renal Indication cell carcinoma where patient is intolerant of NICE approved axitinib Status In development Publication date 12 month cost impact 2nd line treatment of hormone receptor positive, HER2 negative advanced breast cancer, in combination with exemestane, in post menopausal women without symptomatic visceral disease after recurrence or progression following a non steroidal aromatase inhibitor who have not received previous exemestane Published Feb-17 (<£1m p/a for England) Dec-16 £8.9m (based on list price).