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TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5). Chen XL, Serrano D, Ghobadi F, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S. PLoS One. 2016 Mar 29;11(3):e0151837. doi: 10.1371/journal.pone.0151837. eCollection 2016. PMID: 27023180 Editorial: Cytokines in inflammation, aging, cancer and obesity. Ilangumaran S, Ferbeyre G. Cytokine. 2016 Mar 17. pii: S1043-4666(16)30050-3. doi: 10.1016/j.cyto.2016.03.011. [Epub ahead of print] No abstract available. PMID:26997465 Interleukin-15 deficiency promotes the development of T-cell acute lymphoblastic leukemia in non-obese diabetes mice with severe combined immunodeficiency. Bobbala D, Kandhi R, Chen X, Mayhue M, Bouchard E, Yan J, Knecht H, Barabé F, Ramanathan S, Ilangumaran S. Leukemia. 2016 Feb 15. doi: 10.1038/leu.2016.28. [Epub ahead of print] No abstract available. PMID:26876593 Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease. Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, Chen YG, Rola-Pleszczynski M, Menendez A, Ilangumaran S, Ramanathan S. Cytokine. 2016 Feb 8. pii: S1043-4666(16)30020-5. doi: 10.1016/j.cyto.2016.01.020. [Epub ahead of print] PMID:26868085 Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes. Bobbala D, Mayhue M, Menendez A, Ilangumaran S, Ramanathan S. Cell Mol Immunol. 2016 Feb 8. doi: 10.1038/cmi.2015.102. [Epub ahead of print] PMID:26853723 The hepatocyte growth factor (HGF)-MET receptor tyrosine kinase signaling pathway: Diverse roles in modulating immune cell functions. Ilangumaran S, Villalobos-Hernandez A, Bobbala D, Ramanathan S. Cytokine. 2016 Jan 25. pii: S1043-4666(15)30126-5. doi: 10.1016/j.cyto.2015.12.013. [Epub ahead of print] PMID:26822708 Negative regulation of the hepatic fibrogenic response by suppressor of cytokine signaling 1. Kandhi R, Bobbala D, Yeganeh M, Mayhue M, Menendez A, Ilangumaran S. Cytokine. 2015 Dec 31. pii: S1043-4666(15)30120-4. doi: 10.1016/j.cyto.2015.12.007. [Epub ahead of print] PMID:26748724 Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of CIP1/WAF1 p21 in the liver. Yeganeh M, Gui Y, Kandhi R, Bobbala D, Tobelaim WS, Saucier C, Yoshimura A, Ferbeyre G, Ramanathan S, Ilangumaran S. Oncogene. 2016 Jan 4. doi: 10.1038/onc.2015.485. [Epub ahead of print] PMID:26725321 The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis. Gharagozloo M, Mahvelati TM, Imbeault E, Gris P, Zerif E, Bobbala D, Ilangumaran S, Amrani A, Gris D. J Neuroinflammation. 2015 Oct 31;12:198. doi: 10.1186/s12974-015-0414-5. PMID:26521018 GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes. Chen XL, Serrano D, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S. PLoS One. 2015 Oct 6;10(10):e0139019. doi: 10.1371/journal.pone.0139019. eCollection 2015. PMID:26440416 Tumour-promoting role of SOCS1 in colorectal cancer cells. Tobelaim WS, Beaurivage C, Champagne A, Pomerleau V, Simoneau A, Chababi W, Yeganeh M, Thibault P, Klinck R, Carrier JC, Ferbeyre G, Ilangumaran S, Saucier C. Sci Rep. 2015 Sep 22;5:14301. doi: 10.1038/srep14301. PMID:26391193 Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma. Gui Y, Yeganeh M, Donates YC, Tobelaim WS, Chababi W, Mayhue M, Yoshimura A, Ramanathan S, Saucier C, Ilangumaran S. Oncogene. 2015 Nov 12;34(46):5718-28. doi: 10.1038/onc.2015.20. Epub 2015 Mar 2. PMID:25728680 Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease. Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, Chen YG, Rola-Pleszczynski M, Menendez A, Ilangumaran S, Ramanathan S. Cytokine. 2016 Feb 8. pii: S1043-4666(16)30020-5. doi: 10.1016/j.cyto.2016.01.020. [Epub ahead of print] PMID:26868085 Platelet-Derived Growth Factor Receptor Activation Promotes the Prodestructive Invadosome-Forming Phenotype of Synoviocytes from Patients with Rheumatoid Arthritis. Charbonneau M, Lavoie RR, Lauzier A, Harper K, McDonald PP, Dubois CM. J Immunol. 2016 Apr 15;196(8):3264-75. doi: 10.4049/jimmunol.1500502. Epub 2016 Mar 14. PMID:26976956 Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses. Sylvain-Prévost S, Ear T, Simard FA, Fortin CF, Dubois CM, Flamand N, McDonald PP. J Immunol. 2015 Dec 1;195(11):5393-403. doi: 10.4049/jimmunol.1402752. Epub 2015 Oct 21. PMID:26491199 Cellular signalling of cysteinyl leukotriene type 1 receptor variants CysLT1-G300S and CysLT1-I206S. Yaddaden L, Véronneau S, Thompson MD, Rola-Pleszczynski M, Stankova J. Prostaglandins Leukot Essent Fatty Acids. 2016 Feb;105:1-8. doi: 10.1016/j.plefa.2015.12.004. Epub 2015 Dec 21. PMID:26869085 Differential Contribution of BLT1 and BLT2 to Leukotriene B4-Induced Human NK Cell Cytotoxicity and Migration. Wang M, Mostafa El-Maghraby N, Turcotte S, Rola-Pleszczynski M, Stankova J. Mediators Inflamm. 2015;2015:389849. doi: 10.1155/2015/389849. Epub 2015 Dec 1. PMID:26696753 Fülöp T, Dupuis G, Witkowski JM, Larbi A. The role of imunosenescence in the development of age-related diseases. Rev Invest Clin. 2016 68(2):84-91. PMID: 27103044 Baëhl S, Garneau H, Lorrain D, Viens I, Svotelis A, Lord JM, Cabana F, Larbi A, Dupuis G, Fülöp T. Alterations in monocyte phenotypes and functions after a hip fracture in elderly individuals: A 6-month longitudinal study. Gerontology. 2016 Jan 27. [Epub ahead of print] PMID: 26812523 Interactions between bone cells and biomaterials: An update. Beauvais S, Drevelle O, Jann J, Lauzon MA, Foruzanmehr M, Grenier G, Roux S, Faucheux N. Front Biosci (Schol Ed). 2016 Jun 1;8:227-63. PMID: 27100704 Autophagy and Phospho-Inositide Dependent Kinase 1 (PDK1) -Related Kinome in Pagetic Osteoclasts. McManus S, Bisson M, Chamberland R, Roy M, Nazari S, Roux S. J Bone Miner Res. 2016 Feb 5. doi: 10.1002/jbmr.2806. [Epub ahead of print] PMID: 26848537